Biophysical reviews最新文献_第4页

An attempt of Seibutsu-Butsuri in Kyoto IUPAB Congress 2024. 2024年京都IUPAB大会上Seibutsu-Butsuri的尝试。

IF 4.9

Biophysical reviews Pub Date : 2024-10-18 eCollection Date: 2024-10-01 DOI: 10.1007/s12551-024-01241-2

Tamiki Komatsuzaki

引用次数: 0

Biophysical Reviews special issue for the 21st IUPAB congress and 62nd meeting of the Biophysical Society of Japan, Kyoto, Japan, 2024. 《生物物理评论》第21届IUPAB大会特刊和第62届日本生物物理学会会议，日本京都，2024年。

IF 4.9

Biophysical reviews Pub Date : 2024-10-17 eCollection Date: 2024-10-01 DOI: 10.1007/s12551-024-01247-w

Damien Hall, Wilma K Olson

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Novel imaging and biophysical approaches to study tissue hydraulics in mammalian folliculogenesis. 研究哺乳动物卵泡发育组织水力学的新成像和生物物理方法。

IF 4.9

Biophysical reviews Pub Date : 2024-10-07 eCollection Date: 2024-10-01 DOI: 10.1007/s12551-024-01231-4

Jake Turley, Kim Whye Leong, Chii Jou Chan

引用次数: 0

Advances in mechanotransduction and sonobiology: effects of audible acoustic waves and low-vibration stimulations on mammalian cells. 机械转导和声生物学研究进展：可听声波和低振动刺激对哺乳动物细胞的影响。

IF 4.9

Biophysical reviews Pub Date : 2024-10-07 eCollection Date: 2024-12-01 DOI: 10.1007/s12551-024-01242-1

D Del Rosario-Gilabert, A Valenzuela-Miralles, G Esquiva

{"title":"Advances in mechanotransduction and sonobiology: effects of audible acoustic waves and low-vibration stimulations on mammalian cells.","authors":"D Del Rosario-Gilabert, A Valenzuela-Miralles, G Esquiva","doi":"10.1007/s12551-024-01242-1","DOIUrl":"10.1007/s12551-024-01242-1","url":null,"abstract":"In recent decades, research on mechanotransduction has advanced considerably, focusing on the effects of audible acoustic waves (AAWs) and low-vibration stimulation (LVS), which has propelled the field of sonobiology forward. Taken together, the current evidence demonstrates the influence of these biosignals on key cellular processes, such as growth, differentiation and migration in mammalian cells, emphasizing the determining role of specific physical parameters during stimulation, such as frequency, sound pressure level/amplitude and exposure time. These mechanical waves interact with various cellular elements, including ion channels, primary cilia, cell-cell adhesion receptors, cell-matrix and extracellular matrix proteins, and focal adhesion complexes. These components connect with the cytoskeletal fibre network, enabling the transmission of mechanical stimuli towards the nucleus. The nucleus, in turn, linked to the cytoskeleton via the linkers of the nucleoskeleton and cytoskeleton complex, acts as a mechanosensitive centre, not only responding to changes in cytoskeletal stiffness and nuclear tension but also regulating gene expression through the transcriptional co-activator YAP/TAZ and interactions between chromatin and the nuclear envelope. This intricate chain of mechanisms highlights the potential of sonobiology in various fields, including dentistry, regenerative medicine, tissue engineering and cancer research. However, progress in these fields requires the establishment of standardized measurement methodologies and biocompatible experimental setups to ensure the reproducibility of results.","PeriodicalId":9094,"journal":{"name":"Biophysical reviews","volume":"16 6","pages":"783-812"},"PeriodicalIF":4.9,"publicationDate":"2024-10-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11735818/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143000007","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Biological sensing of fluid flow-lessons from PIEZO1. 流体流动的生物传感-来自PIEZO1的教训。

IF 4.9

Biophysical reviews Pub Date : 2024-10-04 eCollection Date: 2024-12-01 DOI: 10.1007/s12551-024-01246-x

David J Beech, Charline Fagnen, Antreas C Kalli

引用次数: 0

Nonthermal fluctuations accelerate biomolecular motors. 非热波动加速生物分子马达。

IF 4.9

Biophysical reviews Pub Date : 2024-10-02 eCollection Date: 2024-10-01 DOI: 10.1007/s12551-024-01238-x

Takayuki Ariga

{"title":"Nonthermal fluctuations accelerate biomolecular motors.","authors":"Takayuki Ariga","doi":"10.1007/s12551-024-01238-x","DOIUrl":"https://doi.org/10.1007/s12551-024-01238-x","url":null,"abstract":"Intracellular transport is essential for maintaining cellular function. This process is driven by different mechanisms in prokaryotic and eukaryotic cells. In small prokaryotic cells, diffusion is the primary means of transport, while larger eukaryotic cells also rely on active transport by molecular motors such as kinesin and dynein. Recently, it has become evident that, in addition to diffusion based on thermal fluctuations (Brownian motion), which was conventionally considered a diffusion mechanism within living cells, nonthermal fluctuations generated by metabolic activities play a crucial role in intracellular diffusion. Similarly, while molecular motors have been proposed to exploit thermal fluctuations in the environment following the direct observation and manipulation of single molecules, they have also been reported to utilize nonthermal fluctuations in recent years. This review begins with a brief overview of the historical knowledge of diffusive intracellular transport, which has been extended from the thermal fluctuations to the nonthermal fluctuations generated by metabolic activity. It then introduces recent findings on how nonthermal fluctuations accelerate the motion of molecular motors and discusses future perspectives on the general effects of these fluctuations on molecules in living cells.","PeriodicalId":9094,"journal":{"name":"Biophysical reviews","volume":"16 5","pages":"605-612"},"PeriodicalIF":4.9,"publicationDate":"2024-10-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11604964/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142766071","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Extreme-value analysis in nano-biological systems: applications and implications. 纳米生物系统中的极值分析：应用和意义。

IF 4.9

Biophysical reviews Pub Date : 2024-10-02 eCollection Date: 2024-10-01 DOI: 10.1007/s12551-024-01239-w

Kumiko Hayashi, Nobumichi Takamatsu, Shunki Takaramoto

{"title":"Extreme-value analysis in nano-biological systems: applications and implications.","authors":"Kumiko Hayashi, Nobumichi Takamatsu, Shunki Takaramoto","doi":"10.1007/s12551-024-01239-w","DOIUrl":"https://doi.org/10.1007/s12551-024-01239-w","url":null,"abstract":"Extreme value analysis (EVA) is a statistical method that studies the properties of extreme values of datasets, crucial for fields like engineering, meteorology, finance, insurance, and environmental science. EVA models extreme events using distributions such as Fréchet, Weibull, or Gumbel, aiding in risk prediction and management. This review explores EVA's application to nanoscale biological systems. Traditionally, biological research focuses on average values from repeated experiments. However, EVA offers insights into molecular mechanisms by examining extreme data points. We introduce EVA's concepts with simulations and review its use in studying motor protein movements within cells, highlighting the importance of in vivo analysis due to the complex intracellular environment. We suggest EVA as a tool for extracting motor proteins' physical properties in vivo and discuss its potential in other biological systems. While there have been only a few applications of EVA to biological systems, it holds promise for uncovering hidden properties in extreme data, promoting its broader application in life sciences.","PeriodicalId":9094,"journal":{"name":"Biophysical reviews","volume":"16 5","pages":"571-579"},"PeriodicalIF":4.9,"publicationDate":"2024-10-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11604884/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142765911","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Dimensional reduction and adaptation-development-evolution relation in evolved biological systems. 进化生物系统的降维与适应-发展-进化关系。

IF 4.9

Biophysical reviews Pub Date : 2024-09-30 eCollection Date: 2024-10-01 DOI: 10.1007/s12551-024-01233-2

Kunihiko Kaneko

{"title":"Dimensional reduction and adaptation-development-evolution relation in evolved biological systems.","authors":"Kunihiko Kaneko","doi":"10.1007/s12551-024-01233-2","DOIUrl":"10.1007/s12551-024-01233-2","url":null,"abstract":"Living systems are complex and hierarchical, with diverse components at different scales, yet they sustain themselves, grow, and evolve over time. How can a theory of such complex biological states be developed? Here we note that for a hierarchical biological system to be robust, it must achieve consistency between micro-scale (e.g., molecular) and macro-scale (e.g., cellular) phenomena. This allows for a universal theory of adaptive change in cells based on biological robustness and consistency between cellular growth and molecular replication. Here, we show how adaptive changes in high-dimensional phenotypes (biological states) are constrained to low-dimensional space, leading to the derivation of a macroscopic law for cellular states. The theory is then extended to evolution, leading to proportionality between evolutionary and environmental responses, as well as proportionality between phenotypic variances due to noise and due to genetic changes. The universality of the results across several models and experiments is demonstrated. Then, by further extending the theory of evolutionary dimensional reduction to multicellular systems, the relationship between multicellular development and evolution, in particular, the developmental hourglass, is demonstrated. Finally, the possibility of collapse of dimensional reduction under nutrient limitation is discussed.","PeriodicalId":9094,"journal":{"name":"Biophysical reviews","volume":"16 5","pages":"639-649"},"PeriodicalIF":4.9,"publicationDate":"2024-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11604870/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142766202","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Microtubule choreography: spindle self-organization during cell division. 微管编排：细胞分裂过程中的纺锤体自组织。

IF 4.9

Biophysical reviews Pub Date : 2024-09-30 eCollection Date: 2024-10-01 DOI: 10.1007/s12551-024-01236-z

Amruta Sridhara, Yuta Shimamoto

引用次数: 0

Unveiling the multifaceted potential of amyloid fibrils: from pathogenic myths to biotechnological marvels. 揭示淀粉样蛋白原纤维的多方面潜力：从致病神话到生物技术奇迹。

IF 4.9

Biophysical reviews Pub Date : 2024-09-30 eCollection Date: 2024-12-01 DOI: 10.1007/s12551-024-01232-3

Gauri Tyagi, Shinjinee Sengupta

{"title":"Unveiling the multifaceted potential of amyloid fibrils: from pathogenic myths to biotechnological marvels.","authors":"Gauri Tyagi, Shinjinee Sengupta","doi":"10.1007/s12551-024-01232-3","DOIUrl":"10.1007/s12551-024-01232-3","url":null,"abstract":"Amyloid fibrils, historically stigmatized due to their association with diseases like Alzheimer's and Parkinson's, are now recognized as a distinct class of functional proteins with extraordinary potential. These highly ordered, cross-β-sheet protein aggregates are found across all domains of life, playing crucial physiological roles. In bacteria, functional amyloids like curli fibers are essential for surface adhesion, biofilm formation, and viral DNA packaging. Fungal prions exploit amyloid conformations to regulate translation, metabolism, and virulence, while mammalian amyloids are integral to melanin synthesis, hormone storage, and antimicrobial defense. The stability and hydrophobic nature of amyloid scaffolds underpin these diverse biological functions. Beyond their natural roles, amyloid fibrils offer unique capabilities in biomedicine, nanotechnology, and materials science. Their exceptional mechanical strength and biocompatibility make them ideal for controlled drug delivery, tissue engineering scaffolds, and enzyme immobilization. The intrinsic fluorescence and optical properties of certain amyloids open up innovative applications in biosensors, molecular probes, and optoelectronic devices. Furthermore, amyloid fibrils can template metal nanowires, enhance conducting materials, and form nanocomposites by integrating with polymers. This newfound appreciation for the functional diversity of amyloids has ignited intense research efforts to elucidate their molecular mechanisms, stability, and tunable properties. By unraveling the structural intricacies of functional amyloids, researchers aim to harness their remarkable attributes for groundbreaking biomedical therapies, advanced nanomaterials, and sustainable biotechnological innovations. This review explores the transformative journey of amyloids from pathological entities to biotechnological marvels, highlighting their vast potential across agriculture, environmental remediation, and industrial processes.","PeriodicalId":9094,"journal":{"name":"Biophysical reviews","volume":"16 6","pages":"737-751"},"PeriodicalIF":4.9,"publicationDate":"2024-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11735760/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143000012","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0