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Vibrational spectroscopy and multiphoton microscopy for label-free visualization of nervous system degeneration and regeneration 振动光谱学和多光子显微镜用于神经系统退化和再生的无标记可视化
Biophysical reviews Pub Date : 2023-10-05 DOI: 10.1007/s12551-023-01158-2
Roberta Galli, Ortrud Uckermann
{"title":"Vibrational spectroscopy and multiphoton microscopy for label-free visualization of nervous system degeneration and regeneration","authors":"Roberta Galli, Ortrud Uckermann","doi":"10.1007/s12551-023-01158-2","DOIUrl":"https://doi.org/10.1007/s12551-023-01158-2","url":null,"abstract":"Abstract Neurological disorders, including spinal cord injury, peripheral nerve injury, traumatic brain injury, and neurodegenerative diseases, pose significant challenges in terms of diagnosis, treatment, and understanding the underlying pathophysiological processes. Label-free multiphoton microscopy techniques, such as coherent Raman scattering, two-photon excited autofluorescence, and second and third harmonic generation microscopy, have emerged as powerful tools for visualizing nervous tissue with high resolution and without the need for exogenous labels. Coherent Raman scattering processes as well as third harmonic generation enable label-free visualization of myelin sheaths, while their combination with two-photon excited autofluorescence and second harmonic generation allows for a more comprehensive tissue visualization. They have shown promise in assessing the efficacy of therapeutic interventions and may have future applications in clinical diagnostics. In addition to multiphoton microscopy, vibrational spectroscopy methods such as infrared and Raman spectroscopy offer insights into the molecular signatures of injured nervous tissues and hold potential as diagnostic markers. This review summarizes the application of these label-free optical techniques in preclinical models and illustrates their potential in the diagnosis and treatment of neurological disorders with a special focus on injury, degeneration, and regeneration. Furthermore, it addresses current advancements and challenges for bridging the gap between research findings and their practical applications in a clinical setting.","PeriodicalId":9094,"journal":{"name":"Biophysical reviews","volume":"36 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135481232","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The 7th Congress of Biophysicists of Russia - conference proceedings 第七届俄罗斯生物物理学家大会论文集
Biophysical reviews Pub Date : 2023-10-01 DOI: 10.1007/s12551-023-01150-w
{"title":"The 7th Congress of Biophysicists of Russia - conference proceedings","authors":"","doi":"10.1007/s12551-023-01150-w","DOIUrl":"https://doi.org/10.1007/s12551-023-01150-w","url":null,"abstract":"","PeriodicalId":9094,"journal":{"name":"Biophysical reviews","volume":"17 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135661822","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Adam, amigo, brain, and K channel 亚当,朋友,大脑和K频道
Biophysical reviews Pub Date : 2023-10-01 DOI: 10.1007/s12551-023-01163-5
Sodikdjon A. Kodirov
{"title":"Adam, amigo, brain, and K channel","authors":"Sodikdjon A. Kodirov","doi":"10.1007/s12551-023-01163-5","DOIUrl":"https://doi.org/10.1007/s12551-023-01163-5","url":null,"abstract":"","PeriodicalId":9094,"journal":{"name":"Biophysical reviews","volume":"22 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136199112","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Novel biocatalysts based on enzymes in complexes with nano- and micromaterials 基于酶与纳米和微材料配合物的新型生物催化剂
Biophysical reviews Pub Date : 2023-10-01 DOI: 10.1007/s12551-023-01146-6
M. G. Holyavka, S. S. Goncharova, Y. A. Redko, M. S. Lavlinskaya, A. V. Sorokin, V. G. Artyukhov
{"title":"Novel biocatalysts based on enzymes in complexes with nano- and micromaterials","authors":"M. G. Holyavka, S. S. Goncharova, Y. A. Redko, M. S. Lavlinskaya, A. V. Sorokin, V. G. Artyukhov","doi":"10.1007/s12551-023-01146-6","DOIUrl":"https://doi.org/10.1007/s12551-023-01146-6","url":null,"abstract":"","PeriodicalId":9094,"journal":{"name":"Biophysical reviews","volume":"279 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136117790","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Microorganisms for the oxidation of nitrated cellulose in its effluents (review) 硝化纤维素废水中的微生物氧化(综述)
Biophysical reviews Pub Date : 2023-10-01 DOI: 10.1007/s12551-023-01159-1
Yana V. Ryzhmanova, Lidia V. Avdeeva, Elena A. Saratovskikh, Viktoria A. Shcherbakova, Evgeniy V. Golosov, Rashit N. Yarullin
{"title":"Microorganisms for the oxidation of nitrated cellulose in its effluents (review)","authors":"Yana V. Ryzhmanova, Lidia V. Avdeeva, Elena A. Saratovskikh, Viktoria A. Shcherbakova, Evgeniy V. Golosov, Rashit N. Yarullin","doi":"10.1007/s12551-023-01159-1","DOIUrl":"https://doi.org/10.1007/s12551-023-01159-1","url":null,"abstract":"","PeriodicalId":9094,"journal":{"name":"Biophysical reviews","volume":"159 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135760266","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Hemodynamics of vascular shunts: trends, challenges, and prospects 血管分流的血流动力学:趋势、挑战和前景
Biophysical reviews Pub Date : 2023-10-01 DOI: 10.1007/s12551-023-01149-3
Julia Kuyanova, Andrei Dubovoi, Aleksei Fomichev, Dmitrii Khelimskii, Daniil Parshin
{"title":"Hemodynamics of vascular shunts: trends, challenges, and prospects","authors":"Julia Kuyanova, Andrei Dubovoi, Aleksei Fomichev, Dmitrii Khelimskii, Daniil Parshin","doi":"10.1007/s12551-023-01149-3","DOIUrl":"https://doi.org/10.1007/s12551-023-01149-3","url":null,"abstract":"","PeriodicalId":9094,"journal":{"name":"Biophysical reviews","volume":"198 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135849894","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Problems of human spermatozoa cryopreservation: research methods, solutions 人类精子冷冻保存的问题:研究方法、解决方案
Biophysical reviews Pub Date : 2023-10-01 DOI: 10.1007/s12551-023-01133-x
Anna Ivanova, Ekaterina Simonenko, Sergey Yakovenko, Vasiliy Spiridonov
{"title":"Problems of human spermatozoa cryopreservation: research methods, solutions","authors":"Anna Ivanova, Ekaterina Simonenko, Sergey Yakovenko, Vasiliy Spiridonov","doi":"10.1007/s12551-023-01133-x","DOIUrl":"https://doi.org/10.1007/s12551-023-01133-x","url":null,"abstract":"","PeriodicalId":9094,"journal":{"name":"Biophysical reviews","volume":"31 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136117650","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Experimental detection of conformational transitions between forms of DNA: problems and prospects DNA形态之间构象转换的实验检测:问题和前景
Biophysical reviews Pub Date : 2023-10-01 DOI: 10.1007/s12551-023-01143-9
Elena A. Zubova, Ivan A. Strelnikov
{"title":"Experimental detection of conformational transitions between forms of DNA: problems and prospects","authors":"Elena A. Zubova, Ivan A. Strelnikov","doi":"10.1007/s12551-023-01143-9","DOIUrl":"https://doi.org/10.1007/s12551-023-01143-9","url":null,"abstract":"","PeriodicalId":9094,"journal":{"name":"Biophysical reviews","volume":"2 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136117416","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
The use of a chemiluminescence in the assessment of the nanomaterials antioxidant activity 利用化学发光法评价纳米材料的抗氧化活性
Biophysical reviews Pub Date : 2023-10-01 DOI: 10.1007/s12551-023-01148-4
Marina V. Zvereva, Anna V. Zhmurova
{"title":"The use of a chemiluminescence in the assessment of the nanomaterials antioxidant activity","authors":"Marina V. Zvereva, Anna V. Zhmurova","doi":"10.1007/s12551-023-01148-4","DOIUrl":"https://doi.org/10.1007/s12551-023-01148-4","url":null,"abstract":"","PeriodicalId":9094,"journal":{"name":"Biophysical reviews","volume":"54 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136117804","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
The 7th Congress of Biophysicists of Russia - conference proceedings 第七届俄罗斯生物物理学家大会论文集
Biophysical reviews Pub Date : 2023-10-01 DOI: 10.1007/s12551-023-01151-9
{"title":"The 7th Congress of Biophysicists of Russia - conference proceedings","authors":"","doi":"10.1007/s12551-023-01151-9","DOIUrl":"https://doi.org/10.1007/s12551-023-01151-9","url":null,"abstract":"","PeriodicalId":9094,"journal":{"name":"Biophysical reviews","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135763050","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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