BioinformationPub Date : 2025-06-30eCollection Date: 2025-01-01DOI: 10.6026/973206300211693
Gadigeppa H Chittaragi, Dileep Khubya, Veluri Ganesh
{"title":"Linking serum malondialdehyde with dyslipidemia in patients with metabolic syndrome.","authors":"Gadigeppa H Chittaragi, Dileep Khubya, Veluri Ganesh","doi":"10.6026/973206300211693","DOIUrl":"10.6026/973206300211693","url":null,"abstract":"<p><p>Dyslipidemia and obesity is becoming an increasingly serious public health issue. Therefore, it is of interest to determine the serum levels of malondialdehyde (MDA) with dyslipidemia in patients with metabolic syndrome. The routine demographic, anthropometric and the biochemical parameters analyzed. Additionally, the degree of lipid peroxidation was measured by serum levels of malondialdehyde (MDA). The body mass index, systolic and diastolic blood pressure, fasting blood sugars, lipid profile significantly elevated in metabolic syndrome patients when compared to healthy controls. The serum MDA levels significantly elevated and correlated positively with abdominal hyperglycemia, hypertension, obesity and negatively with HDL (p=0.0001**). Thus, the early detection of people at risk for getting metabolic syndrome can be improved by measuring the MDA biomarker.</p>","PeriodicalId":8962,"journal":{"name":"Bioinformation","volume":"21 6","pages":"1693-1698"},"PeriodicalIF":1.9,"publicationDate":"2025-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12449504/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145111847","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Comparative evaluation of resiliency of mono-poly coated two different acrylic based tissue conditioners - An <i>in vitro</i> study.","authors":"Apurva Kurhade, Vidushi Jayaswal, Mukesh Sisodiya, Harsh Chansoria, Alka Gupta, Shivani Gupta","doi":"10.6026/973206300211775","DOIUrl":"10.6026/973206300211775","url":null,"abstract":"<p><p>The resiliency of two monomer-coated acrylic-based tissue conditioners over 28 days is compared using an <i>in vitro</i> study. Sixty resin specimens were prepared and tested at five intervals using a durometer to measure viscoelastic properties. Initially, Orthoplast Acryton exhibited higher resiliency, but Maarc Soft Liner showed better performance from Day 7 onwards. Both materials demonstrated comparable resiliency after two weeks, suggesting stabilization over time. Mono-poly coating effectively preserved the softness and elasticity, supporting clinical use for short- to medium-term denture conditioning.</p>","PeriodicalId":8962,"journal":{"name":"Bioinformation","volume":"21 6","pages":"1775-1778"},"PeriodicalIF":1.9,"publicationDate":"2025-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12449524/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145111861","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
BioinformationPub Date : 2025-06-30eCollection Date: 2025-01-01DOI: 10.6026/973206300211454
Rohit Divya Gunvanthbhai, Siva Subramanian N, Mahalakshmi B
{"title":"Effect of music and yoga on stress among Indian women during pregnancy.","authors":"Rohit Divya Gunvanthbhai, Siva Subramanian N, Mahalakshmi B","doi":"10.6026/973206300211454","DOIUrl":"10.6026/973206300211454","url":null,"abstract":"<p><p>Effect of yoga and music on stress among antenatal Indian women Gujarat is of interest. Hence, a quasi-experimental design was used among 180 women divided equally into Yoga and Music groups. Interventions were delivered over two weeks (Yoga) and one week (Music), with stress measured using the Perceived Stress Scale. Both therapies significantly reduced stress. However, yoga showed a greater improvement (mean difference: 1.889 vs. 1.111). Correlation analysis revealed a stronger relationship in the music group, though overall effect was higher in the yoga group. These findings support integrating complementary therapies into prenatal care.</p>","PeriodicalId":8962,"journal":{"name":"Bioinformation","volume":"21 6","pages":"1454-1457"},"PeriodicalIF":1.9,"publicationDate":"2025-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12449522/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145111870","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Effect of ropivacaine with and without intrathecal fentanyl for spinal anesthesia among patients with scorpion bite history: A case control study.","authors":"Sonali Tripathi, Vineet Mandrah, Ritesh Upadhyay, Ashwini Kumar Patel","doi":"10.6026/973206300211577","DOIUrl":"10.6026/973206300211577","url":null,"abstract":"<p><p>Effect of ropivacaine with and without intrathecal fentanyl for spinal anesthesia among patients with scorpion bite is of interest. Patients in the fentanyl-ropivacaine combination group had faster onset of sensory blockade (5.2±1.1 versus 7.8±1.3 minutes, p<0.001) and significantly longer analgesia duration (290±15 versus 180±12 minutes, p<0.001) than patients in the ropivacaine-alone group. Hemodynamic stability and the incidence of adverse effects were similar between the two groups. These results indicate that intrathecal fentanyl enhances the efficacy of ropivacaine in this distinct patient population without compromising safety.</p>","PeriodicalId":8962,"journal":{"name":"Bioinformation","volume":"21 6","pages":"1577-1580"},"PeriodicalIF":1.9,"publicationDate":"2025-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12449530/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145111892","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
BioinformationPub Date : 2025-06-30eCollection Date: 2025-01-01DOI: 10.6026/973206300211362
Ramachandra Himateja C, Rashmi G
{"title":"Linking changes in macular thickness post cataract surgery with post-operative visual acuity.","authors":"Ramachandra Himateja C, Rashmi G","doi":"10.6026/973206300211362","DOIUrl":"10.6026/973206300211362","url":null,"abstract":"<p><p>Cataract surgery is the most commonly performed surgery, with a 90% success rate in restoring vision; however, Cystoid Macular Edema (CME) is a frequent cause of reduced vision post-operatively. This study evaluated changes in macular thickness and its correlation with post-operative visual acuity following Small Incision Cataract Surgery in 100 patients who underwent pre and post-operative macular OCT. Mean macular thickness increased from 205.14 ± 35.65 µm pre-operatively to 254.28 ± 26.68 µm at one week post-operatively, then decreased to 224.53 ± 26.73 µm by the fourth week. Visual acuity improved in 70% of patients to better than 6/9 at one week and in 96% by the fourth week post-surgery. Post-operative visual decline is often due to transient macular edema, which typically resolves without significant long-term impact on vision.</p>","PeriodicalId":8962,"journal":{"name":"Bioinformation","volume":"21 6","pages":"1362-1366"},"PeriodicalIF":1.9,"publicationDate":"2025-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12449485/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145111913","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"<i>in vitro</i> evaluation of mutagenic potential in common oral hygiene products.","authors":"Shweta Hegde, Prashanth Shetty, Mridula Nair, Arindam Dalal, Pankaj Bajaj, Sandhya James","doi":"10.6026/973206300211510","DOIUrl":"10.6026/973206300211510","url":null,"abstract":"<p><p>The mutagenic potential of five commonly used oral hygiene products using the Ames test is of interest. Fluoridated and herbal toothpastes showed no mutagenicity. Alcohol-based and chlorhexidine mouthwashes demonstrated moderate mutagenic effects, especially with metabolic activation. Hydrogen peroxide mouth rinse exhibited the highest mutagenicity without S9 activation. Thus, the need for further <i>in vivo</i> investigation to validate safety profiles is relevant.</p>","PeriodicalId":8962,"journal":{"name":"Bioinformation","volume":"21 6","pages":"1510-1513"},"PeriodicalIF":1.9,"publicationDate":"2025-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12449565/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145111830","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Awareness and knowledge among dental teaching faculty of graphene in dentistry: Application.","authors":"Swapna Basimi, Swathi Devi Enaganti, Lakshmana Rao Bathala, Narayana Chava, Vaishnavi Devi Majeti, Venkata Vaibhav Puvvada","doi":"10.6026/973206300211589","DOIUrl":"10.6026/973206300211589","url":null,"abstract":"<p><p>Graphene is a novel nanomaterial which garnered interest for its promising applications in dentistry due to its superior mechanical and antimicrobial properties. Therefore, it is of interest to the knowledge and awareness of graphene among dental faculty across India through a cross-sectional survey using a 14-item questionnaire. Among 407 respondents, most were Associate Professors, with a notable awareness of graphene's potential despite no current clinical use in their institutions. The findings highlight a knowledge base that supports future integration of graphene into dental curricula and practice. Expanding educational initiatives may facilitate its eventual clinical adoption.</p>","PeriodicalId":8962,"journal":{"name":"Bioinformation","volume":"21 6","pages":"1589-1592"},"PeriodicalIF":1.9,"publicationDate":"2025-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12449553/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145111887","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
BioinformationPub Date : 2025-06-30eCollection Date: 2025-01-01DOI: 10.6026/973206300211672
Geetha S, Vinutha Shankar M S
{"title":"Enrichment-induced behavioural changes in MPTP mice.","authors":"Geetha S, Vinutha Shankar M S","doi":"10.6026/973206300211672","DOIUrl":"10.6026/973206300211672","url":null,"abstract":"<p><p>Parkinson's disease (PD) is a progressive neurodegenerative disorder characterized by motor and non-motor deficits due to dopaminergic neuron loss. Neuro-protective effects of enriched environment have been well established. Therefore, it is of interest to examine the effects of enriched housing in a 1-methyl-4- phenyl 1, 2, 3, 6-tetrahydropyridine (MPTP)-induced mouse model of PD. Thirty-two male C57BL/6 mice were divided into standard and enriched housing groups, with MPTP or saline treatment. MPTP mice in standard housing showed impaired motor function, whereas MPTP mice in enriched housing did not show decline in motor function, demonstrating the beneficial effects of environmental enrichment in MPTP mice.</p>","PeriodicalId":8962,"journal":{"name":"Bioinformation","volume":"21 6","pages":"1672-1676"},"PeriodicalIF":1.9,"publicationDate":"2025-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12449499/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145111905","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Behavioral outcome prediction among children using machine learning.","authors":"Samir P V, Aruna Kumari G, Nandini Biradar, Kodali Srija, Debasmita Das, Sukabhogi Anusha","doi":"10.6026/973206300211555","DOIUrl":"10.6026/973206300211555","url":null,"abstract":"<p><p>Behavioural management in paediatric dentistry is essential for treatment success, yet predicting a child's behavior remains a challenge. This study used machine learning models on data from 120 children aged 4-10 years, incorporating clinical and historical variables such as age, dental history and parental anxiety. Among the models tested, Random Forest achieved the highest accuracy (87.5%) in predicting behavior based on the Frankl scale. Key predictors of negative behavior included younger age, high parental anxiety and prior negative dental experiences. These findings highlight the potential of machine learning to support behavior guidance planning and improve clinical outcomes.</p>","PeriodicalId":8962,"journal":{"name":"Bioinformation","volume":"21 6","pages":"1555-1558"},"PeriodicalIF":1.9,"publicationDate":"2025-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12449484/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145111921","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
BioinformationPub Date : 2025-06-30eCollection Date: 2025-01-01DOI: 10.6026/973206300211543
Jekee Patel, Parin Patel, Himarshi Upadhyay, Falak Saiyed, Huma Saiyad, Swarnim Rathod
{"title":"Prediction of post-operative complications among diabetic patients undergoing major surgery using biomarkers.","authors":"Jekee Patel, Parin Patel, Himarshi Upadhyay, Falak Saiyed, Huma Saiyad, Swarnim Rathod","doi":"10.6026/973206300211543","DOIUrl":"10.6026/973206300211543","url":null,"abstract":"<p><p>Evaluation of pre-operative HbA1c, CRP, IL-6, and procalcitonin levels among 150 diabetic patients undergoing major surgery is of interest. Elevated HbA1c (>8%) and CRP were strongly associated with postoperative complications such as wound infections and prolonged ICU stay. IL-6 and procalcitonin show moderates predictive accuracy for systemic inflammation. Biomarker profiling proved useful for identifying high-risk patients. Incorporating these tests can improve surgical planning and postoperative care.</p>","PeriodicalId":8962,"journal":{"name":"Bioinformation","volume":"21 6","pages":"1543-1546"},"PeriodicalIF":1.9,"publicationDate":"2025-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12449550/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145111938","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}