{"title":"Knowledge, attitudes and perceptions of AI in medicine among Indian doctors.","authors":"Chidurala Rahul, Shriraam Karunakaran, Venkatesh Karthikeyan, Suresh Varadharajan, Swetha Chandru","doi":"10.6026/973206300211061","DOIUrl":"10.6026/973206300211061","url":null,"abstract":"<p><p>Artificial Intelligence (AI) is revolutionizing healthcare. However, there is a significant lack of understanding among medical practitioners on AI. Therefore, it is of interest to evaluate the knowledge, awareness, experience and perceptions regarding AI among 250 medical students, doctors and members of the Indian Medical Association (IMA). The questionnaire based survey revealed that though the participants were well aware of the general AI concepts, not even half felt that it would be helpful for diagnosis and treatment purposes. Also, 82.9% (n=207) reported not taking any formal courses on AI, which again emphasizes a learning gap. Results suggest better training of AI within the medical education framework to prepare healthcare professionals to face imminent trends.</p>","PeriodicalId":8962,"journal":{"name":"Bioinformation","volume":"21 5","pages":"1061-1068"},"PeriodicalIF":1.9,"publicationDate":"2025-05-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12357720/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144871226","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
BioinformationPub Date : 2025-05-31eCollection Date: 2025-01-01DOI: 10.6026/973206300211103
Randhir Kumar, Amit Goel, Ruchi Pandey, Arshad Jamal Sayed, Surya Dahiya, Jeethu John Jerry, Sukriti Mukherjee
{"title":"Laser assisted versus photodynamic decontamination of peri-implant mucositis: A split mouth RCT.","authors":"Randhir Kumar, Amit Goel, Ruchi Pandey, Arshad Jamal Sayed, Surya Dahiya, Jeethu John Jerry, Sukriti Mukherjee","doi":"10.6026/973206300211103","DOIUrl":"10.6026/973206300211103","url":null,"abstract":"<p><p>The clinical efficacy of diode-laser assisted decontamination (DLAD) and Photodynamic Therapy (PDT) in managing peri-implant mucositis around platform-switch implants is of interest. A split-mouth randomized controlled trial (RCT) was conducted with 50 participants (100 sites), each receiving both DLAD and PDT on different sides of the mouth. Clinical parameters were measured before and after treatment at baseline, 1 month, 3 months and 6 months. Both DLAD and PDT are effective in treating peri-implant mucositis around platform-switch implants, with no significant difference in clinical outcomes.</p>","PeriodicalId":8962,"journal":{"name":"Bioinformation","volume":"21 5","pages":"1103-1107"},"PeriodicalIF":1.9,"publicationDate":"2025-05-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12357736/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144871227","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A framework for biosafety assessment of microbial strains in Biotechnology applications.","authors":"Swati Shrivastava, Abhishek Sharma, Nidhi Sharma, Alishan Fehmina","doi":"10.6026/973206300211158","DOIUrl":"10.6026/973206300211158","url":null,"abstract":"<p><p>Biosafety refers to the principles and practices that prevent unintentional exposure to biological agents and limit their potential harm to humans and the environment. Therefore, we developed a comprehensive biosafety assessment framework for 40 microbial strains used in biotechnology, evaluating five key parameters: pathogenicity, immunogenicity, environmental persistence, genetic stability, and taxonomy. Principal component analysis showed that 84% of the risk variation was unrelated to taxonomy, emphasizing the need for strain-specific evaluations. Among the strains assessed, 76% of fungi triggered high levels of TNF-α and IL-6 in immune cell assays, and 68% persisted beyond 30 days in simulated environmental conditions. Meanwhile, 71% of gram-negative bacteria carried virulence genes (<i>et al.</i>, hlyA, invA) and exhibited significant cytotoxicity in human cell cultures. These findings support a data-driven, parameter-based approach for advancing biosafety standards in modern biotechnology.</p>","PeriodicalId":8962,"journal":{"name":"Bioinformation","volume":"21 5","pages":"1158-1162"},"PeriodicalIF":1.9,"publicationDate":"2025-05-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12357737/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144871269","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
BioinformationPub Date : 2025-05-31eCollection Date: 2025-01-01DOI: 10.6026/973206300211279
Madiha Khan, Satish Maran, Ruba Khan, Ami Rawal, Palak Jain, Ali Khan
{"title":"Microleakage between conventional GIC, RMGIC and glass hybrid bulkfill restorative system to restore class I cavities in primary molars: An <i>in vitro</i> study.","authors":"Madiha Khan, Satish Maran, Ruba Khan, Ami Rawal, Palak Jain, Ali Khan","doi":"10.6026/973206300211279","DOIUrl":"10.6026/973206300211279","url":null,"abstract":"<p><p>The microleakage of conventional GIC to that of resin modified GIC and bulk filled hybrid restorative system (GIC) to restore class I cavities in primary molars is of interest. Hence, a total of 60 extracted human primary molar teeth collected were divided into three main groups. Class I cavity was prepared in all teeth and restore with conventional GIC, resin modified GIC and bulk filled hybrid restorative system (GIC). Sections were viewed under stereomicroscope and the degree of microleakage was evaluated using specific scoring criteria. Among the three restorative materials, Glass hybrid Bulkfil restorative system GIC can be considered as the best material in the terms of microleakage.</p>","PeriodicalId":8962,"journal":{"name":"Bioinformation","volume":"21 5","pages":"1279-1285"},"PeriodicalIF":1.9,"publicationDate":"2025-05-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12357691/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144871299","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Periapical healing in endodontic retreatment: A comparative study of nano-hydroxyapatite with and without PRF.","authors":"Shelly Singh, Jnana Ranjan Swain, Megha Gugnani, Ashtha Arya, Ranjita Singh Baghel, Samra Shafique","doi":"10.6026/973206300211195","DOIUrl":"10.6026/973206300211195","url":null,"abstract":"<p><p>The efficacy of nano-hydroxyapatite (nHA) alone and in combination with platelet-rich fibrin (PRF) in enhancing periapical bone healing following endodontic retreatment is of interest. Thirty-two patients with failed endodontic treatment in anterior teeth were divided into two groups. After retreatment, apicoectomy and root-end filling with mineral trioxide aggregate (MTA) were performed. Group 1 received nHA alone, while Group 2 received a combination of nHA and PRF in the periapical cavity. Follow-ups at 1, 3, and 6 months showed significant lesion size reduction in both groups, with faster healing in the nHA+PRF group at 1 month, but no long-term differences.</p>","PeriodicalId":8962,"journal":{"name":"Bioinformation","volume":"21 5","pages":"1195-1200"},"PeriodicalIF":1.9,"publicationDate":"2025-05-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12357677/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144871310","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
BioinformationPub Date : 2025-05-31eCollection Date: 2025-01-01DOI: 10.6026/973206300210978
Altaf H Malik, Irshad A Misgar
{"title":"Two versus single needle arthrocentesis of TMJ for internal derangement.","authors":"Altaf H Malik, Irshad A Misgar","doi":"10.6026/973206300210978","DOIUrl":"10.6026/973206300210978","url":null,"abstract":"<p><p>The efficacy of arthrocentesis with two needles compared with one needle for the treatment of internal derangement of temporomandibular joint (TMJ) is of interest. Fifty patients aged between 17 to 39 years comprised the study material in the department of Oral & Maxillofacial surgery at Govt Dental College Srinagar (India). Clinical evaluation of the patients was done before the procedure and 1 week and 6 months after postoperatively. Intensity of TMJ pain and maximal mouth opening were recorded at each follow-up visit. Arthrocentesis improves the symptoms of the patients with internal derangement with closed lock but addition of other needle didn't improve the results.</p>","PeriodicalId":8962,"journal":{"name":"Bioinformation","volume":"21 5","pages":"978-981"},"PeriodicalIF":1.9,"publicationDate":"2025-05-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12357673/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144871313","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Taboos among general population about dental extraction in Sangli region: A prospective study.","authors":"Sanjay Byakodi, Mushtak Khan, Jyoti Biradar, Kishan Dudhat, Nidhhi Bihani, Swati Priya","doi":"10.6026/973206300211714","DOIUrl":"10.6026/973206300211714","url":null,"abstract":"<p><p>Indians reside in rural areas. Ancient Indian taboos and ideologies have a negative correlation with preventative dental health behaviours; the goal of this study was to identify the current frequency of these beliefs and cultural taboos around dentistry. The taboos and myths related to dental extraction were considered. 33% believe that eye sight will be affected while 53% believed that extracted teeth should be buried. 66% considered that extraction should be done only when tooth is shaking and around 59% considered placement of medicaments like zandu balm or vicks to relieve dental pain.</p>","PeriodicalId":8962,"journal":{"name":"Bioinformation","volume":"21 5","pages":"1714-1718"},"PeriodicalIF":1.9,"publicationDate":"2025-05-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12357656/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144871338","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Evaluation of surface topography of two different heat treated NiTi file systems used with sodium hypochlorite: A stereomicroscope and SEM study.","authors":"Anisha Parmar, Niraj Kinariwala, Nirav Parekh, Vishwesh Joshi, Riya Modi, Urooj Desai","doi":"10.6026/973206300211257","DOIUrl":"10.6026/973206300211257","url":null,"abstract":"<p><p>The surface grooves on endodontic files act as stress concentration and it lowers their susceptibility to fatigue fracture. Hence, 80 first mandibular molars were prepared with 40 rotary instruments, 20 One Curve (OC; Micro-Mega) and 20 TruNatomy (TN; Dentsply Sirona,) rotary files. The files were rotated in mesial curved canals with irrigation with 5.25% sodium hypochlorite (Normal temperature and preheated) and inspected under SEM for surface roughness. Stereomicroscope analysis was done for Unwinding and Distortion. One Curve files showed signs of deformation and distortion earlier as compared to TruNatomy in curved canals. Sodium hypochlorite (Preheated form) affects the surface topography and fatigue resistance of the files.</p>","PeriodicalId":8962,"journal":{"name":"Bioinformation","volume":"21 5","pages":"1257-1265"},"PeriodicalIF":1.9,"publicationDate":"2025-05-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12357726/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144871216","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
BioinformationPub Date : 2025-05-31eCollection Date: 2025-01-01DOI: 10.6026/973206300211011
Ramachandra Himateja C, Sangeetha T, Inchara N
{"title":"Is glycaemic control essential for cataract surgery among patients with diabetes mellitus?","authors":"Ramachandra Himateja C, Sangeetha T, Inchara N","doi":"10.6026/973206300211011","DOIUrl":"10.6026/973206300211011","url":null,"abstract":"<p><p>Diabetic patients are at increased risk of cataracts, with higher risks of intraoperative and postoperative complications. Therefore, it is of interest to explore the challenges in performing cataract surgery on diabetic patients. Hence, a prospective study of 300 Type II diabetes patients undergoing cataract surgery found that 69.3% achieved post-operative visual acuity of 6/18 or better. Common complications included iritis (9.7%) and striate keratopathy (7.7%). The severity of diabetic retinopathy, diabetic macular edema, and poor preoperative visual acuity were linked to worse postoperative outcomes. Intravitreal steroids may improve outcomes in patients with diabetic macular edema.</p>","PeriodicalId":8962,"journal":{"name":"Bioinformation","volume":"21 5","pages":"1011-1015"},"PeriodicalIF":1.9,"publicationDate":"2025-05-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12357705/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144871223","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Knowledge and practice on oral hygiene maintenance among medical students in India.","authors":"Bharat Jayant Sumbh, Shweta Gangotri, Rishi Thukral, Heeralal Chokotiya, Ashtha Arya, Ajay Kumar","doi":"10.6026/973206300211226","DOIUrl":"10.6026/973206300211226","url":null,"abstract":"<p><p>Oral hygiene is vital in preventing dental caries, periodontal diseases and systemic conditions like stroke and heart disease. Therefore, it is of interest to evaluate oral health awareness among MBBS students and interns using a pretested, structured questionnaire. Data analysis was performed using the Chi-square test with a significance threshold of 0.05. A significant gender difference was observed in brushing frequency (P = 0.005) and only 36.9% of students reported brushing twice daily. Hence, there is a need to enhance oral health education in medical curricula for effective preventive healthcare.</p>","PeriodicalId":8962,"journal":{"name":"Bioinformation","volume":"21 5","pages":"1226-1230"},"PeriodicalIF":1.9,"publicationDate":"2025-05-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12357667/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144871224","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}