Bioinformation最新文献_第10页

Age dependent vestibulo-ocular reflex gain in video head impulse test among normal Indians. 正常印度人在视频头脉冲测试中的前庭眼反射增益与年龄有关。

IF 1.9

Bioinformation Pub Date : 2024-05-31 eCollection Date: 2024-01-01 DOI: 10.6026/973206300200520

Saraswathi Avula, Saran Kumar, Senthi Vadivu, Mohan Kameswaran

{"title":"Age dependent vestibulo-ocular reflex gain in video head impulse test among normal Indians.","authors":"Saraswathi Avula, Saran Kumar, Senthi Vadivu, Mohan Kameswaran","doi":"10.6026/973206300200520","DOIUrl":"10.6026/973206300200520","url":null,"abstract":"Determination of the normative data of Vestibulo-Ocular Reflex gain using VHIT of all three semicircular canals (anterior, posterior, horizontal) on both sides in different age groups is of interest. This is an observational study comprised of 10 healthy individuals in each decade from less than 10 years to 80 years of both sexes making a total of 80. The study was done using the equipment SYNAPSYS VHIT ULMER with Software EVOLUTION 3.0. Mean VOR gain of each decade for all the semicircular canals is calculated and they are compared using ANOVA (Analysis of variance). In our study, percentage of patients with overt saccades is nil. Hence, in our study, the occurrence of covert saccades was insignificant as compared to the above studies. Age dependent VOR gain in normal individuals did not have any significance in our study of 80 patients performed by video head impulse test. VOR gain in our study is not affected by age. Normative data for different age groups obtained compared among different age groups showing no significant difference in Mean VOR gain. The normative values of VOR gain can be compared to patients with dizziness thus helping in determining any vestibular loss.","PeriodicalId":8962,"journal":{"name":"Bioinformation","volume":"20 5","pages":"520-527"},"PeriodicalIF":1.9,"publicationDate":"2024-05-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11309093/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141916024","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Benefits and risks of complete denture therapy in fully edentulous Indian patients. 全口无牙的印度患者接受全口义齿治疗的好处和风险。

IF 1.9

Bioinformation Pub Date : 2024-05-31 eCollection Date: 2024-01-01 DOI: 10.6026/973206300200551

Diptesh S Rami, Bhagyashree S Sutaria, Vishal B Parmar, Kishan Detroja, Rajesh Sethuraman, Trupti Makwana

{"title":"Benefits and risks of complete denture therapy in fully edentulous Indian patients.","authors":"Diptesh S Rami, Bhagyashree S Sutaria, Vishal B Parmar, Kishan Detroja, Rajesh Sethuraman, Trupti Makwana","doi":"10.6026/973206300200551","DOIUrl":"10.6026/973206300200551","url":null,"abstract":"The perceptions of the patients regarding the benefits and risk of complete denture treatment in completely edentulous patients are of interest. The study composed of 79 participants who presented themselves for complete denture therapy. The perception of the participants towards the complete denture therapy was recorded using a validated questionnaire. The answers of the questionnaire were evaluated in three domains: (1) Benefits (positive perception) of the complete denture therapy' (2) Risks (Negative perception) of the complete denture therapy and (3) Consequences of no treatment. The data were tabulated for descriptive analysis. The average age of the total population was 62.22 ranging from 58 to 80 years. Total population included in the study shows positive perception regarding the complete denture therapy. The benefits of the complete denture therapy show highest score (1817) by all the participants while the risks of the complete denture therapy show lowest score (237). The gender, denture experience and the socioeconomic status had no influence on the perception towards the complete denture therapy. Participants showed positive perception towards the complete denture therapy with highest score in benefits and lowest score for the risks of the complete denture therapy. The perception of the complete denture therapy was not influenced by the gender, denture experience and the socioeconomic status.","PeriodicalId":8962,"journal":{"name":"Bioinformation","volume":"20 5","pages":"551-556"},"PeriodicalIF":1.9,"publicationDate":"2024-05-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11309117/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141916026","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Application of CAD-CAM in Dentistry. CAD-CAM 在牙科中的应用。

IF 1.9

Bioinformation Pub Date : 2024-05-31 eCollection Date: 2024-01-01 DOI: 10.6026/973206300200547

Niladri Maiti, Niva Mahapatra, Dhruvi Patel, Jeel Chanchad, Anushka Saurabhbhai Shah, S K Mahboob Rahaman, Pratik Surana

引用次数: 0

Centella asiatica ameliorates AlCl3 and D-galactose induced nephrotoxicity in rats via modulation of oxidative stress. 积雪草通过调节氧化应激改善氯化铝和 D-半乳糖诱导的大鼠肾毒性

IF 1.9

Bioinformation Pub Date : 2024-05-31 eCollection Date: 2024-01-01 DOI: 10.6026/973206300200508

Thirupathirao Vishnumukkala, Prarthana Kalerammana Gopalakrishna, Barani Karikalan, Warren Thomas, Saravanan Jagadeesan, Samaila Musa Chiroma, Nurul Huda Mohd Nor, Mohamad Aris Mohd Moklas

{"title":"Centella asiatica ameliorates AlCl3 and D-galactose induced nephrotoxicity in rats via modulation of oxidative stress.","authors":"Thirupathirao Vishnumukkala, Prarthana Kalerammana Gopalakrishna, Barani Karikalan, Warren Thomas, Saravanan Jagadeesan, Samaila Musa Chiroma, Nurul Huda Mohd Nor, Mohamad Aris Mohd Moklas","doi":"10.6026/973206300200508","DOIUrl":"10.6026/973206300200508","url":null,"abstract":"Nephrotoxicity is a condition caused by toxic effects of medications and poisons resulting in the rapid decline of kidney function. Centella asiatica is a medicinal herb with antioxidative and anti-inflammatory characteristics that is used to treat a variety of ailments. The present study intends to explore the ability of Centella asiatica in preventing AlCl3 and D-Galactose-induced nephrotoxicity in rats. In this study 30 male albino Wistar rats were induced with nephrotoxicity using AlCl3 and D-galactose, and oral administration of Centella asiatica extract (100, 200, and 300mg/kg/day) was administered for 70 days. The kidneys were extracted after treatment and levels of oxidative and antioxidative enzymes, serum creatinine, and serum albumin were measured. The kidney's histopathological changes were studied. Administration of Centella asiatica extract significantly increased serum albumin, superoxide dismutase (SOD), and catalase levels in kidney homogenates while suppressing serum creatinine and malondialdehyde (MDA) levels and attenuating histopathological changes associated with nephrotoxicity. Centella asiatica extract lowered serum creatinine and oxidative stress levels in a drug-induced nephrotoxicity rat model, while simultaneously increasing serum albumin levels, as evidenced by mitigation of histological changes and normalisation of biomarkers of oxidative stress in the kidney.","PeriodicalId":8962,"journal":{"name":"Bioinformation","volume":"20 5","pages":"508-514"},"PeriodicalIF":1.9,"publicationDate":"2024-05-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11309103/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141916058","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Congenital ocular and its adnexal anomalies among Indian pediatric age groups. 印度儿童先天性眼部及其附件异常。

IF 1.9

Bioinformation Pub Date : 2024-04-30 eCollection Date: 2024-01-01 DOI: 10.6026/973206300200323

Preethi Chava, Chaitra Mc, Raveena J, Amulya Padmini

{"title":"Congenital ocular and its adnexal anomalies among Indian pediatric age groups.","authors":"Preethi Chava, Chaitra Mc, Raveena J, Amulya Padmini","doi":"10.6026/973206300200323","DOIUrl":"10.6026/973206300200323","url":null,"abstract":"An analysis of the congenital etiologies of ocular morbidity in children of age 0-12 years is of interest. Hence, this study was conducted over a period of 2 years from Jan 2021- Dec 2023 at RL Jalappa Hospital and Research center that is attached to Sri Devaraj Urs Medical College, Tamaka, Kolar, Karnataka, India. Out of 56 patients, 57% were male and 43% were female children. 31 (55%) of mothers belonged to age group between 20-30 years and 24 (43%) between 31-40 years and 1(2%) between 41-50 years. Out of 56 patients, 14 (25%) of them had positive family history. 34 (61%) of them had consanguious marriage. 14 parents (41%) out of 34 are married to second degree consanguinity (brother/sister/grandparent/grandchild) and 20 (59%) belonged to third degree consanguinity (aunt/uncle/niece/nephew/great-grandparent/great-grandchild). Bilateral involvement was seen in 31 (55%). Nasolacrimal duct anomalies were found to be the most common (32%) followed by congenital esotropia (14%). Education, awareness, counseling about risks of consanguinity and other risk factors such as maternal age, infections, medications during pregnancy, vaccination must be a routine practice in healthcare set up. This can significantly reduce morbidity and prevent blindness.","PeriodicalId":8962,"journal":{"name":"Bioinformation","volume":"20 4","pages":"323-326"},"PeriodicalIF":1.9,"publicationDate":"2024-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11161881/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141295459","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Linking IL-6 and hsCRP among Indian patients with myocardial infarction. 印度心肌梗死患者中 IL-6 和 hsCRP 的联系。

IF 1.9

Bioinformation Pub Date : 2024-04-30 eCollection Date: 2024-01-01 DOI: 10.6026/973206300200378

Virendra Verma, Pavan Kumar Sharma, Shashi Prabha Singh, Devajit Sarmah, Rajni Patel, Poonam Verma, Shiv Shanker Tripathi, Deepa Arya, Manish Kumar Verma

{"title":"Linking IL-6 and hsCRP among Indian patients with myocardial infarction.","authors":"Virendra Verma, Pavan Kumar Sharma, Shashi Prabha Singh, Devajit Sarmah, Rajni Patel, Poonam Verma, Shiv Shanker Tripathi, Deepa Arya, Manish Kumar Verma","doi":"10.6026/973206300200378","DOIUrl":"10.6026/973206300200378","url":null,"abstract":"The association between serum interleukin-6 (IL-6) and highly sensitive C - reactive protein (hsCRP) as predictors of the risk factors for Myocardial Infarction. The study included a total of 50 patients with Myocardial Infarction, aged between 25 to 74 years. The levels of hsCRP were measured using the immunoturbidimetry method, while Interleukin 6 was estimated using the sandwich ELISA method. Statistical analysis was conducted using SPSS version 21.0, with p values calculated using Quartile ratio, ANOVA unpaired t-test, and Kaplan-Meier Curve Method. A p-value of less than 0.05 was considered statistically significant. All participants underwent a questionnaire, physical examination, medical history assessment, and laboratory tests. The results of the study showed that there was a significant correlation between IL-6 and hsCRP levels in the Quartile groups, as well as with lipid profiles. The Kaplan-Meier method also demonstrated a significant association between IL-6 and hsCRP levels in participants. The comparison of biomarkers further supported these findings. Thus, data shows that elevated levels of hsCRP and IL-6 could serve as valuable diagnostic markers for predicting Acute Myocardial Infarction. Our study strongly suggests that IL-6 could be a powerful marker in evaluating the Myocardial Infarction.","PeriodicalId":8962,"journal":{"name":"Bioinformation","volume":"20 4","pages":"378-385"},"PeriodicalIF":1.9,"publicationDate":"2024-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11161886/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141295517","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Screening, awareness and challenges for colorectal cancer treatment in Saudi Arabia: an update. 沙特阿拉伯结直肠癌治疗的筛查、认识和挑战：最新情况。

IF 1.9

Bioinformation Pub Date : 2024-04-30 eCollection Date: 2024-01-01 DOI: 10.6026/973206300200397

Samer Mohammed Hassan Alqarni, Mohammed Saad Alamri, Peter Natesan Pushparaj, Irfan Rather, Zafar Iqbal, Muhammad Asif, Mahmood Rasool

{"title":"Screening, awareness and challenges for colorectal cancer treatment in Saudi Arabia: an update.","authors":"Samer Mohammed Hassan Alqarni, Mohammed Saad Alamri, Peter Natesan Pushparaj, Irfan Rather, Zafar Iqbal, Muhammad Asif, Mahmood Rasool","doi":"10.6026/973206300200397","DOIUrl":"10.6026/973206300200397","url":null,"abstract":"Colorectal cancer (CRC) is the second most common cancer in the world. In Saudi Arabia, CRC is the most common cancer in males and the third most common in females, and its incidence rate is rising as the country continues to develop. However, the country does not have a national CRC screening program for CRC. This review aims to review recent studies that have attempted to address and rectify this issue and discern the most notable and prevalent barriers. Despite these efforts, guidelines are still lacking. Two prospective studies have been conducted in recent years, one of which was a national pilot screening program conducted by the Ministry of Health (MOH). While both had a similar number of participants, the colonoscopy rate for patients with a positive fecal immunochemical test (FIT) in the MOH program was only 20% compared to 75.8% in the Al-Kharj program. Awareness of the Saudi population regarding CRC and its screening appears to be insufficient. The most common barriers to patients' willingness to undergo screening were embarrassment, fear, and pain. Barriers to physicians are mostly related to factors outside their hands, such as lack of equipment and time. We conclude that efforts should be made to establish a national screening program and improve awareness of the population and physicians.","PeriodicalId":8962,"journal":{"name":"Bioinformation","volume":"20 4","pages":"397-403"},"PeriodicalIF":1.9,"publicationDate":"2024-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11161890/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141295521","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

From network pharmacology to molecular docking analysis of sterubin targets for Alzheimer. 从网络药理学到针对阿尔茨海默氏症的固醇蛋白靶点的分子对接分析。

IF 1.9

Bioinformation Pub Date : 2024-04-30 eCollection Date: 2024-01-01 DOI: 10.6026/973206300200327

Sittarthan Viswanathan, Thennavan Arumugam, Rengaraj Sivaraj, Srihari Subhashri Rajendran, Vimalavathini Ramesh, Kavimani Subramanian, A Hannah Rachel Vasanthi

引用次数: 0

Measurement of mandibular incisive canal diameter using cone beam computed tomography. 使用锥形束计算机断层扫描测量下颌切管直径。

IF 1.9

Bioinformation Pub Date : 2024-04-30 eCollection Date: 2024-01-01 DOI: 10.6026/973206300200394

Prachi Anand, Dhaval N Mehta, Dewanshu Kumar, Richa Thakur, Rohit Malviya, Rohit Kumar

{"title":"Measurement of mandibular incisive canal diameter using cone beam computed tomography.","authors":"Prachi Anand, Dhaval N Mehta, Dewanshu Kumar, Richa Thakur, Rohit Malviya, Rohit Kumar","doi":"10.6026/973206300200394","DOIUrl":"10.6026/973206300200394","url":null,"abstract":"Cone beam computed tomography was used for measuring the diameter of a Mandibular incisive canal. The dental practice can now visualize small bone structures with low dose and high spatial resolution due to the introduction of CBCT (Cone Beam Computed Tomography). Therefore, it is of interest to measure the diameter of the MIC (Mandibular Incisive Canal) using the CBCT. Fifty CBCT scans obtained for implant placement preoperative planning were included in the study material. Observers carefully examined the CBCT data to determine the MIC's presence & position. The inner diameter of the MIC was measured by taking the longest distance between the inner cortical borders of the canal which was further analyzed using software CS3D software. The collected data were further subjected to statistical analysis. The average mean of the population was 1.7130±.5178. The average diameter of MIC in males was 1.735±.5406 and in females was 1.6800±.4934. Complications from implant surgery in the anterior mandible may be prevented by utilizing CBCT scans to analyze the smallest diameter of the MIC.","PeriodicalId":8962,"journal":{"name":"Bioinformation","volume":"20 4","pages":"394-396"},"PeriodicalIF":1.9,"publicationDate":"2024-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11161880/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141295519","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Dimensional stability and surface hardness of inter-occlusal recording materials. 记录材料的尺寸稳定性和表面硬度。

IF 1.9

Bioinformation Pub Date : 2024-04-30 eCollection Date: 2024-01-01 DOI: 10.6026/973206300200344

Khyati N Gosai, Ina B Patel, Pooja Poonia, Bhagyashree Sutaria, Mahima Trivedi, Sarita Mori

引用次数: 0