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Clinical evaluation of facial soft-tissue profile using OCTA criteria in patients: A cross-sectional study. 使用OCTA标准对患者面部软组织轮廓的临床评价：一项横断面研究。
IF 1.9
Bioinformation Pub Date : 2026-06-30 eCollection Date: 2026-01-01 DOI: 10.6026/973206300223614
Sameer Chauhan, Sunil Kumar Gulia, Gaurav Ahuja, J Dhanuja Rani, Adrika De, Parth Suthar, Rahul Tiwari, Anil Managutti
{"title":"Clinical evaluation of facial soft-tissue profile using OCTA criteria in patients: A cross-sectional study.","authors":"Sameer Chauhan, Sunil Kumar Gulia, Gaurav Ahuja, J Dhanuja Rani, Adrika De, Parth Suthar, Rahul Tiwari, Anil Managutti","doi":"10.6026/973206300223614","DOIUrl":"10.6026/973206300223614","url":null,"abstract":"<p><p>Facial soft-tissue profile plays a crucial role in determining facial esthetics and treatment outcomes in orthodontic patients. Therefore, it is of interest to evaluate the facial soft-tissue profile characteristics using the OCTA criteria among orthodontic patients. A cross- sectional observational study was conducted among 120 patients undergoing orthodontic assessment. Most patients demonstrated balanced facial soft-tissue profiles. Significant variations in lip prominence and nasolabial angle were observed among different malocclusion groups. Thus, data shows that OCTA criteria provide a practical and reliable approach for clinical soft-tissue profile assessment.</p>","PeriodicalId":8962,"journal":{"name":"Bioinformation","volume":"22 6","pages":"3614-3618"},"PeriodicalIF":1.9,"publicationDate":"2026-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13545945/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148896384","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Impact of NSAIDs on post-operative bleeding in minor dental and oral surgery: A clinical study. 非甾体抗炎药对口腔小手术术后出血的影响：一项临床研究。
IF 1.9
Bioinformation Pub Date : 2026-06-30 eCollection Date: 2026-01-01 DOI: 10.6026/973206300223604
Harshawardhan Ravindra Kadam, Akshit Vermani, Vivek Vivek, Aishwarya Mahajan, Giri K Y, Vaishnavi Thota, Rahul Tiwari
{"title":"Impact of NSAIDs on post-operative bleeding in minor dental and oral surgery: A clinical study.","authors":"Harshawardhan Ravindra Kadam, Akshit Vermani, Vivek Vivek, Aishwarya Mahajan, Giri K Y, Vaishnavi Thota, Rahul Tiwari","doi":"10.6026/973206300223604","DOIUrl":"10.6026/973206300223604","url":null,"abstract":"<p><p>Post-operative bleeding is a common concern after minor dental and oral surgical procedures. NSAID use after surgery remains controversial because of its potential effect on platelet aggregation and bleeding time. A prospective observational study was conducted on 100 patients undergoing routine dental extractions, third molar surgery, alveoloplasty, or minor soft tissue procedures. All patients received NSAID-based analgesic regimens following surgery. Statistical analysis demonstrated no significant association between NSAID administration and clinically significant post-operative bleeding. Thus, we show that NSAIDs can be safely prescribed following minor oral surgical procedures when appropriate surgical technique and local hemostatic measures are employed.</p>","PeriodicalId":8962,"journal":{"name":"Bioinformation","volume":"22 6","pages":"3604-3608"},"PeriodicalIF":1.9,"publicationDate":"2026-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13545941/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148896431","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Comparative evaluation of fluoride varnish, pit and fissure sealants in preventing dental caries among children. 氟化物清漆、牙窝和牙缝密封剂预防儿童龋齿的比较评价。
IF 1.9
Bioinformation Pub Date : 2026-06-30 eCollection Date: 2026-01-01 DOI: 10.6026/973206300223314
Riddhi Jadeja, Debadrita Ghosh, Devashree Shukla, Nandini Sanjaykumar Bhatt, Dhanuja Rani J, Srinivas Murthy S T
{"title":"Comparative evaluation of fluoride varnish, pit and fissure sealants in preventing dental caries among children.","authors":"Riddhi Jadeja, Debadrita Ghosh, Devashree Shukla, Nandini Sanjaykumar Bhatt, Dhanuja Rani J, Srinivas Murthy S T","doi":"10.6026/973206300223314","DOIUrl":"10.6026/973206300223314","url":null,"abstract":"<p><p>Dental caries remains a highly prevalent chronic disease among children, particularly affecting occlusal surfaces of molars. Therefore, it is of interest to compare effectiveness of fluoride varnish and pit and fissure sealants in preventing dental caries among 120 children. Participants were randomly allocated to two groups, with caries assessment performed at baseline and follow-up using Decayed, Missing and Filled Teeth (DMFT/dmft) index. Both interventions showed reduction in caries, with differences observed in long-term effectiveness and application practicality. Thus, we show comparative evidence on preventive strategies, supporting selection of appropriate interventions in pediatric dentistry.</p>","PeriodicalId":8962,"journal":{"name":"Bioinformation","volume":"22 6","pages":"3314-3318"},"PeriodicalIF":1.9,"publicationDate":"2026-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13545922/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148896432","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Cone beam imaging and audiometric evaluation of the eustachian tube in OSMF: A case-control study. 锥形束成像和耳咽管听力评估在OSMF：一项病例对照研究。
IF 1.9
Bioinformation Pub Date : 2026-06-30 eCollection Date: 2026-01-01 DOI: 10.6026/973206300223556
Reema Manoj, Mandavi Waghmare, Boddu Tejvanti, Richa Kamble, Iqra Malgundkar, Gargie Gharat
{"title":"Cone beam imaging and audiometric evaluation of the eustachian tube in OSMF: A case-control study.","authors":"Reema Manoj, Mandavi Waghmare, Boddu Tejvanti, Richa Kamble, Iqra Malgundkar, Gargie Gharat","doi":"10.6026/973206300223556","DOIUrl":"10.6026/973206300223556","url":null,"abstract":"<p><p>The rising incidence of oral submucous fibrosis (OSMF) among younger Indians and its potentially aggressive progression necessitate investigation of deeper structural changes, including those affecting the eustachian tube (ET). Hence, this 2-year departmental study evaluated morphometric and volumetric alterations in 77 participants (48 OSMF patients and 29 healthy controls) using clinical examination, CBCT and audiometric assessment, with OSMF cases classified by functional stage. Half of the OSMF patients showed an interincisal opening of 25-35 mm (M2) and significant reductions in ET length and volume were observed in the study group compared with controls (p<0.05). ET dimensions and audiometric findings also differed significantly across OSMF stages (M1-M4), indicating progressive structural compromise associated with worsening auditory function (p<0.05). Thus, we report CBCT-based evidence that OSMF is associated with stage-related ET morphometric and volumetric reduction, contributing to auditory impairment and broadening understanding of its deeper oropharyngeal effects.</p>","PeriodicalId":8962,"journal":{"name":"Bioinformation","volume":"22 6","pages":"3556-3561"},"PeriodicalIF":1.9,"publicationDate":"2026-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13545935/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148896457","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Correlation of serum vitamin D, calcium-phosphorus metabolism and functional outcome in osteoporotic fractures. 骨质疏松性骨折患者血清维生素D、钙磷代谢与功能结局的相关性。
IF 1.9
Bioinformation Pub Date : 2026-06-30 eCollection Date: 2026-01-01 DOI: 10.6026/973206300223375
Sonendra Kumar Sharma, Sandeep Kumar Jain, Niket Raj Garg, Vishnu Kumar Gupta, Rajesh Ahirwar, Parul Nema
{"title":"Correlation of serum vitamin D, calcium-phosphorus metabolism and functional outcome in osteoporotic fractures.","authors":"Sonendra Kumar Sharma, Sandeep Kumar Jain, Niket Raj Garg, Vishnu Kumar Gupta, Rajesh Ahirwar, Parul Nema","doi":"10.6026/973206300223375","DOIUrl":"10.6026/973206300223375","url":null,"abstract":"<p><p>Osteoporotic fractures are associated with poor functional recovery in older adults. Therefore, it is of interest to evaluate serum 25-OH-D, calcium, phosphorus, and PTH in 120 fragility fracture patients. Hence, Vitamin D deficiency was observed in 65% of patients and showed significant positive correlation with 6-month functional recovery scores. Elevated PTH levels were negatively associated with recovery outcomes, while calcium and phosphorus were not significant predictors. Thus, we report serum vitamin D as an independent predictor of long-term functional recovery after osteoporotic fractures.</p>","PeriodicalId":8962,"journal":{"name":"Bioinformation","volume":"22 6","pages":"3375-3379"},"PeriodicalIF":1.9,"publicationDate":"2026-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13545971/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148896511","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Serum albumin, NLR and PLR in pre-treatment assessment of bronchiectasis exacerbations. 血清白蛋白、NLR和PLR在支气管扩张加重治疗前评估中的应用。
IF 1.9
Bioinformation Pub Date : 2026-06-30 eCollection Date: 2026-01-01 DOI: 10.6026/973206300223236
Reetu G, Vinod Kumar Viswanathan
{"title":"Serum albumin, NLR and PLR in pre-treatment assessment of bronchiectasis exacerbations.","authors":"Reetu G, Vinod Kumar Viswanathan","doi":"10.6026/973206300223236","DOIUrl":"10.6026/973206300223236","url":null,"abstract":"<p><p>Bronchiectasis severity scores, through useful in disease progression, are inadequate for monitoring exacerbation treatment. Therefore, it is of interest to investigate the correlation between serum albumin, Platelet Lymphocyte Ratio (PLR) and Neutrophil Lymphocyte Ratio (NLR) with disease severity in exacerbated bronchiectasis patients. Serum albumin and NLR demonstrated significant correlation with disease severity, while PLR did not. Post-treatment, both markers showed improvement, indicating their role in treatment monitoring. Thus, we show NLR and serum albumin as reliable biomarkers for assessing severity and monitoring treatment response in bronchiectasis.</p>","PeriodicalId":8962,"journal":{"name":"Bioinformation","volume":"22 6","pages":"3236-3239"},"PeriodicalIF":1.9,"publicationDate":"2026-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13545904/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148896513","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effect of amlodipine and telmisartan on bone metabolism markers in newly diagnosed hypertensive patients. 氨氯地平和替米沙坦对新诊断高血压患者骨代谢指标的影响。
IF 1.9
Bioinformation Pub Date : 2026-06-30 eCollection Date: 2026-01-01 DOI: 10.6026/973206300223768
Kamlesh Garg, Perumal Raveendranath, Sameer Gulati, Sufian Zaheer, Amita Yadav, Ruchika Nandha
{"title":"Effect of amlodipine and telmisartan on bone metabolism markers in newly diagnosed hypertensive patients.","authors":"Kamlesh Garg, Perumal Raveendranath, Sameer Gulati, Sufian Zaheer, Amita Yadav, Ruchika Nandha","doi":"10.6026/973206300223768","DOIUrl":"10.6026/973206300223768","url":null,"abstract":"<p><p>Hypertension may adversely affect bone health, but the skeletal effects of commonly prescribed antihypertensive drugs remain inadequately u nderstood. In this 24-week prospective study, 96 newly diagnosed Stage I hypertensive patients received either Amlodipine (5-10 mg) or Telmisartan (40-80 mg), with serial assessment of bone metabolism markers. Both drugs achieved comparable blood pressure control throughout the study period. Telmisartan significantly reduced PTH and IL-6 levels while enhancing BS-ALP and transiently increasing osteocalcin, whereas Amlodipine demonstrated only a temporary rise in BS-ALP. Thus, data shows the telmisartan may provide additional benefits on bone remodeling and skeletal health in hypertensive patients at risk of fragility.</p>","PeriodicalId":8962,"journal":{"name":"Bioinformation","volume":"22 6","pages":"3768-3772"},"PeriodicalIF":1.9,"publicationDate":"2026-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13545871/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148896516","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Therapeutic effect of Siddhar yogam on varicose veins - A pilot clinical trial. 悉达瑜伽治疗静脉曲张的临床试验。
IF 1.9
Bioinformation Pub Date : 2026-06-30 eCollection Date: 2026-01-01 DOI: 10.6026/973206300223343
Manobala V R, Mahalakshmi V, Sugasini P, Manivannan P, SivaNandini T K, Naveena E, Senthilvel G
{"title":"Therapeutic effect of <i>Siddhar yogam</i> on varicose veins - A pilot clinical trial.","authors":"Manobala V R, Mahalakshmi V, Sugasini P, Manivannan P, SivaNandini T K, Naveena E, Senthilvel G","doi":"10.6026/973206300223343","DOIUrl":"10.6026/973206300223343","url":null,"abstract":"<p><p>Varicose veins are dilated and twisted subcutaneous veins of the lower limbs and represent one of the most commonly reported conditions. The lack of standardized, non-invasive therapeutic interventions for the management of varicose veins often leads to persistent physical discomfort and reduced quality of life for patients. Therefore, it is of interest to evaluate the effect of <i>Siddhar yogam</i> on varicose veins among patients reporting at Ayothidoss Pandithar Hospital, National Institute of Siddha, using Aberdeen Varicose Vein Questionnaire (AVVQ). A single-arm open-label pilot clinical trial was conducted in 30 patients who practiced the prescribed <i>Siddhar yogam</i> protocol for 90 days and outcomes were assessed before and after intervention. Thus, we show a significant reduction in symptoms, indicating the potential effectiveness of <i>Siddhar yogam</i> in managing varicose veins.</p>","PeriodicalId":8962,"journal":{"name":"Bioinformation","volume":"22 6","pages":"3343-3347"},"PeriodicalIF":1.9,"publicationDate":"2026-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13545873/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148896640","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Human trachea and bronchi: Structural adaptations in respiratory health. 人类气管和支气管：呼吸健康的结构适应。
IF 1.9
Bioinformation Pub Date : 2026-06-30 eCollection Date: 2026-01-01 DOI: 10.6026/973206300223264
Ravishankar Kumar, Shravan Kumar, Soni Soni, Dhananjay Kumar, Radhika Raman
{"title":"Human trachea and bronchi: Structural adaptations in respiratory health.","authors":"Ravishankar Kumar, Shravan Kumar, Soni Soni, Dhananjay Kumar, Radhika Raman","doi":"10.6026/973206300223264","DOIUrl":"10.6026/973206300223264","url":null,"abstract":"<p><p>The structural and functional interplay between the human trachea and bronchi remains incompletely characterized, limiting precision in airway diagnosis and therapy. Hence, fifty specimens were comparatively evaluated for gross anatomical, histological and airflow-related parameters, with correlation analysis between structural and functional indices. The trachea showed greater diameter (18.6 ± 2.1 mm), uniform C-shaped cartilage and higher goblet cell density, while the bronchi exhibited cartilage plates, greater smooth muscle thickness (78.6 ± 8.4 μm) and higher air distribution efficiency (p <0.0001). Airway diameter correlated negatively with resistance (r = -0.82) and smooth muscle thickness correlated positively with flexibility (r = 0.79), confirming the trachea as a low-resistance conduit and the bronchi as dynamic airflow modulators. Thus, an integrated structural histological functional profile of the trachea and bronchi with quantitative morphology-airflow correlation, offer an anatomical reference framework for imaging interpretation, airway-device design and management of obstructive airway diseases.</p>","PeriodicalId":8962,"journal":{"name":"Bioinformation","volume":"22 6","pages":"3264-3267"},"PeriodicalIF":1.9,"publicationDate":"2026-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13545929/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148896641","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Artificial intelligence in endodontics: A comprehensive review of applications and advancement. 人工智能在牙髓学中的应用与进展综述。
IF 1.9
Bioinformation Pub Date : 2026-06-30 eCollection Date: 2026-01-01 DOI: 10.6026/973206300223658
Ameer Akhil Ahmed Shaik, Puspita Guha, Dhruvi Patel, Madhura Jadhav, Arindam Banik, Nirav Parmar, Mrunal Dave
{"title":"Artificial intelligence in endodontics: A comprehensive review of applications and advancement.","authors":"Ameer Akhil Ahmed Shaik, Puspita Guha, Dhruvi Patel, Madhura Jadhav, Arindam Banik, Nirav Parmar, Mrunal Dave","doi":"10.6026/973206300223658","DOIUrl":"10.6026/973206300223658","url":null,"abstract":"<p><p>The transformative impact of artificial intelligence (AI) on endodontics is gaining momentum. It highlights advancements in diagnostic accuracy, treatment planning and patient management. By integrating machine learning algorithms and imaging techniques, AI enhances clinical decision-making, reduces procedural errors and improves patient outcomes. Thus, data shows the current applications, challenges and future directions, proposing that AI will shape the future of endodontic practice and enhance the quality of dental care.</p>","PeriodicalId":8962,"journal":{"name":"Bioinformation","volume":"22 6","pages":"3658-3662"},"PeriodicalIF":1.9,"publicationDate":"2026-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13545932/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148896701","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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