{"title":"Periapical healing in endodontic retreatment: A comparative study of nano-hydroxyapatite with and without PRF.","authors":"Shelly Singh, Jnana Ranjan Swain, Megha Gugnani, Ashtha Arya, Ranjita Singh Baghel, Samra Shafique","doi":"10.6026/973206300211195","DOIUrl":null,"url":null,"abstract":"<p><p>The efficacy of nano-hydroxyapatite (nHA) alone and in combination with platelet-rich fibrin (PRF) in enhancing periapical bone healing following endodontic retreatment is of interest. Thirty-two patients with failed endodontic treatment in anterior teeth were divided into two groups. After retreatment, apicoectomy and root-end filling with mineral trioxide aggregate (MTA) were performed. Group 1 received nHA alone, while Group 2 received a combination of nHA and PRF in the periapical cavity. Follow-ups at 1, 3, and 6 months showed significant lesion size reduction in both groups, with faster healing in the nHA+PRF group at 1 month, but no long-term differences.</p>","PeriodicalId":8962,"journal":{"name":"Bioinformation","volume":"21 5","pages":"1195-1200"},"PeriodicalIF":1.9000,"publicationDate":"2025-05-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12357677/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Bioinformation","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.6026/973206300211195","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/1/1 0:00:00","PubModel":"eCollection","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
The efficacy of nano-hydroxyapatite (nHA) alone and in combination with platelet-rich fibrin (PRF) in enhancing periapical bone healing following endodontic retreatment is of interest. Thirty-two patients with failed endodontic treatment in anterior teeth were divided into two groups. After retreatment, apicoectomy and root-end filling with mineral trioxide aggregate (MTA) were performed. Group 1 received nHA alone, while Group 2 received a combination of nHA and PRF in the periapical cavity. Follow-ups at 1, 3, and 6 months showed significant lesion size reduction in both groups, with faster healing in the nHA+PRF group at 1 month, but no long-term differences.
求助内容：
应助结果提醒方式：
京公网安备 11010802042870号
