{"title":"A review on periodontal care: Challenges among geriatric and pediatric patients.","authors":"Pragya G, Anitha Logaranjani K, Prashanthi P, Vijayalakshmi R, Jaideep Mahendra","doi":"10.6026/9732063002001532","DOIUrl":"10.6026/9732063002001532","url":null,"abstract":"<p><p>Periodontal care for geriatric and pediatric patients poses distinct challenges due to age-specific factors. In elderly patients, systemic conditions, medications and reduced dexterity complicate treatment. Pediatric patients face unique issues related to developing dentition and behaviour management. This review reports these challenges and offers strategies for effective, tailored periodontal care. Emphasizing patient-centered approaches improves outcomes for both populations.</p>","PeriodicalId":8962,"journal":{"name":"Bioinformation","volume":"20 11","pages":"1532-1536"},"PeriodicalIF":1.9,"publicationDate":"2024-11-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11953549/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143750912","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
BioinformationPub Date : 2024-11-30eCollection Date: 2024-01-01DOI: 10.6026/9732063002001549
Varun Malhotra, Danish Javed, Tanusha Pathak
{"title":"Effect of <i>Bhastrika Pranayama</i> on neuro- cardiovascular-respiratory function among yoga practitioners.","authors":"Varun Malhotra, Danish Javed, Tanusha Pathak","doi":"10.6026/9732063002001549","DOIUrl":"10.6026/9732063002001549","url":null,"abstract":"<p><p><i>Bhastrika Pranayama</i>, a vigorous yoga breathing technique, impacts both the autonomic nervous system and brain function. This prospective interventional study examined the acute effects of <i>Bhastrika</i> on heart rate variability (HRV) and electroencephalogram (EEG) patterns in 20 regular yoga practitioners. Significant increases in heart rate and sympathetic activity, as well as alterations in brain wave spectra, were observed during and after the practice indicated by a rise in low-frequency (LF) power and the LF/HF ratio, along with a decrease in high-frequency (HF) power and a substantial decrease in beta, theta, alpha and gamma waves while delta waves increased. The findings suggest <i>Bhastrika</i> enhances sympathetic activity and modifies cognitive states. Further research is necessary to understand its long-term benefits and therapeutic potential.</p>","PeriodicalId":8962,"journal":{"name":"Bioinformation","volume":"20 11","pages":"1549-1554"},"PeriodicalIF":1.9,"publicationDate":"2024-11-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11953524/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143750988","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Innovations in denture marking: Forensic applications and clinical implications: A review.","authors":"Ajimol Theresa Jose, Tejaspreet Kaur, Sibani Sarangi, Sania Khan, Shubham Tripathi, Sooriaprakas Chandrasekaran, Ritik Kashwani","doi":"10.6026/9732063002001452","DOIUrl":"10.6026/9732063002001452","url":null,"abstract":"<p><p>Denture marking is a vital tool in forensic odontology and clinical practice, aiding in the identification of dental prostheses, especially in disaster victim identification and cases where traditional methods fail. Techniques are categorized into surface methods like engraving and laser etching and inclusion methods such as embedding RFID tags or barcodes. These markers provide reliable identification, assist in recovering lost prostheses and can be implemented at low cost in routine dental practice. Advancements like RFID technology have made denture marking more efficient and reliable. Overall, denture marking enhances patient safety, reduces redundancy and holds significant medico-legal value.</p>","PeriodicalId":8962,"journal":{"name":"Bioinformation","volume":"20 11","pages":"1542-1548"},"PeriodicalIF":1.9,"publicationDate":"2024-11-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11953542/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143750509","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
BioinformationPub Date : 2024-11-30eCollection Date: 2024-01-01DOI: 10.6026/9732063002001629
Nishath Sayed Abdul, Moaath Ahmad Alsayegh, Eida Ahmed Shahin, Ra'ed Ghaleb Salma, Kholoud Abdullah Alamri
{"title":"Review on oral mucosal lesions in HIV patients with and without highly HAART.","authors":"Nishath Sayed Abdul, Moaath Ahmad Alsayegh, Eida Ahmed Shahin, Ra'ed Ghaleb Salma, Kholoud Abdullah Alamri","doi":"10.6026/9732063002001629","DOIUrl":"10.6026/9732063002001629","url":null,"abstract":"<p><p>This review was hence conducted to understand the prevalence and types of OMLs in individuals with HIV and the influence of highly active antiretroviral therapy (HAART) on these manifestations. A comprehensive search was conducted across multiple databases, namely PubMed, Web of Science, Scopus, EMBASE, CINAHL, Cochrane Library, ProQuest and Google Scholar. Two reviewers independently extracted the data variables. Studies included had a lower risk of bias as per the NOS assessment. The findings revealed a significant prevalence of OMLs among individuals with HIV, with variations in the occurrence and type of these OMLs between individuals on HAART and those not on HART. Overall, it was noted that the occurrence of OMLs was lessened with HAART treatment as compared to those without.</p>","PeriodicalId":8962,"journal":{"name":"Bioinformation","volume":"20 11","pages":"1629-1634"},"PeriodicalIF":1.9,"publicationDate":"2024-11-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11953523/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143750928","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Evaluation of rapid detection methods for H5N1 virus using biosensors: An AI-based study.","authors":"Roberto Eggenhöffner, Paola Ghisellini, Cristina Rando, Simonetta Papa, Allen Khakshooy, Luca Giacomelli","doi":"10.6026/9732063002001516","DOIUrl":"10.6026/9732063002001516","url":null,"abstract":"<p><p>High mortality and zoonotic potential predispose the H5N1 avian influenza virus as a critical threat. knowing that an epidemic could be occurring, quick and precise diagnostic techniques are essential for managing and containing possible epidemics. To detect H5N1 in saliva samples, this study investigates the theoretical design, simulation and evaluation of three kind of biosensors based on different technologies with potential as rapid identifications tools to diagnose quickly H5N1: Lateral Flow Tests (LFT), Field Effect transistors (FET) based electrochemical sensors and Quartz Crystal Microbalance (QCM) sensors. Through detailed AI-based simulations, we show the capabilities, sensitivities and specificities of these biosensors, highlighting their potential for applications in general biology as well as their suitability both for routine home practice and for applications by control entities in public settings. We therefore wish to pave the way to a framework for the quick creation of detection tools that can be swiftly implemented for rapid deployment in case of an outbreak of disease.</p>","PeriodicalId":8962,"journal":{"name":"Bioinformation","volume":"20 11","pages":"1516-1523"},"PeriodicalIF":1.9,"publicationDate":"2024-11-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11953552/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143750992","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
BioinformationPub Date : 2024-11-30eCollection Date: 2024-01-01DOI: 10.6026/9732063002001560
Mohammed Minhaj Ahmed Amer, Amit Kumar Sharma, Mahendra Azad, Nisha Sharma
{"title":"Enhancing osseointegration in dental implants with topical platelet - rich fibrin.","authors":"Mohammed Minhaj Ahmed Amer, Amit Kumar Sharma, Mahendra Azad, Nisha Sharma","doi":"10.6026/9732063002001560","DOIUrl":"10.6026/9732063002001560","url":null,"abstract":"<p><p>The impact of platelet-rich fibrin as a topical application on osseointegration in dental implants is of interest. Hence, a medical questionnaire was used to gather information during the initial interview, including details about past and current medical conditions, temporary and chronic medications, smoking habits and any special dietary restrictions. To assess primary stability, RFA values were recorded on the day of implant placement using the Ostell instrument. A highly significant difference was observed between RFA1 and RFA2 in the buccolingual direction (p ≤ 0.05). The topical application of PRF on implants led to a significant improvement in osseointegration around dental implants compared to conventionally placed implants.</p>","PeriodicalId":8962,"journal":{"name":"Bioinformation","volume":"20 11","pages":"1560-1563"},"PeriodicalIF":1.9,"publicationDate":"2024-11-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11953531/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143751026","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
BioinformationPub Date : 2024-11-30eCollection Date: 2024-01-01DOI: 10.6026/9732063002001654
Lakshay Singla
{"title":"Current trends on clinical audit on surgical record keeping.","authors":"Lakshay Singla","doi":"10.6026/9732063002001654","DOIUrl":"10.6026/9732063002001654","url":null,"abstract":"<p><p>The aim of this audit was to evaluate compliance with the local surgical record-keeping policy, identify areas of non-compliance and recommend improvements. A retrospective review was conducted using 30 randomly selected inpatient records from the surgical department, audited over two quarters (Q1 and Q2 of 2023). Data were extracted via the Electronic Data Management System (EDMS) and analyzed using the trust's record-keeping audit tool. The audit assessed compliance with 30 standards, with 10 standards targeting 100% compliance and 20 standards targeting 75% compliance. The audit highlighted significant deficits in surgical record keeping, with major issues being illegible entries, missing clinician designations and inconsistent use of approved abbreviations. Although improvements were observed in certain areas, such as proper documentation of date and time, further efforts are needed to enhance compliance across all standards. Recommendations include improved induction training, standardized documentation layouts and prompt recording of clinical events.</p>","PeriodicalId":8962,"journal":{"name":"Bioinformation","volume":"20 11","pages":"1654-1657"},"PeriodicalIF":1.9,"publicationDate":"2024-11-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11953533/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143750985","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"<i>In vitro</i> anti-cancer activity of siddha metallo-mineral formulation from Thanga uram with Hela cell lines.","authors":"Sathya Rathish Mohana Jeevanath, Manjari Venkatraman, Kalaivanan Karuppan, Abarna Balasubramani, Natarajan Mohan, Siva Annamalai","doi":"10.6026/9732063002001603","DOIUrl":"10.6026/9732063002001603","url":null,"abstract":"<p><p>The second most common malignant tumour in women worldwide, cervical cancer seriously jeopardizes their health. It has been established that a high-risk Human papillomavirus (HPV) infection is the cause of cervical cancer. Cervical cancer is associated with several risk factors, including reproductive, behavioural and sexual characteristics. Many Siddha practitioners often prescribe Thanga uram (TU), a Siddha metallo-mineral formulation, for genito-urinary diseases, infertility, varicose veins and leucorrhoea. This study aims to evaluate the anti-cancer activity of \"Thanga uram\" against HeLa cell lines. Hela cell lines were used to assess the antiproliferative activity TU using the MTT assay and apoptosis by Annexin V flow cytometry. Thanga uram produced dose-dependent cytotoxic effects against HeLa cell lines with an LC50 value of 145.891µg/mL. Further investigation, using Annexin V flow cytometry, equivalently revealed the late apoptotic effect, with a percentage value of 28.15. Thus, the current study evaluates the effectiveness of Thanga Uram against cervical cancer.</p>","PeriodicalId":8962,"journal":{"name":"Bioinformation","volume":"20 11","pages":"1603-1607"},"PeriodicalIF":1.9,"publicationDate":"2024-11-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11953548/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143750894","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Tumor biomarkers HE4 and CA125 alongside enhanced computed tomography imaging in assessing lymph node metastasis in endometrial cancer.","authors":"Vandana Maurya, Shruti Singh, Shubham Singh, Shashi Prabha Singh, Manish Kumar Verma","doi":"10.6026/9732063002001453","DOIUrl":"10.6026/9732063002001453","url":null,"abstract":"<p><p>The impact of HE4 and CA125 on lymph node metastasis in endometrial cancer and evaluate the diagnostic effectiveness of these biomarkers when combined with enhanced CT imaging to predict lymph node metastasis. The objective is to examine how HE4 and CA125 influence lymph node metastasis and to assess their diagnostic utility when paired with enhanced CT imaging to predict lymph node involvement in endometrial cancer. The study included 326 patients who underwent surgery for endometrial cancer (experimental group), alongside 98 individuals without cancer (control group). A retrospective analysis was carried out to assess the diagnostic efficacy of HE4 and CA125, in combination with enhanced CT, for predicting lymph node metastasis. Levels of HE4 and CA125 were measured and compared between the experimental and control groups, as well as within the lymph node-positive and -negative groups. Significant variations in HE4 and CA125 levels were found between the endometrial cancer and control groups, and between lymph node-positive and -negative subgroups within the endometrial cancer cohort (p < 0.001). The AUC for HE4 was 0.73 (p < 0.001) in premenopausal and 0.578 (p = 0.164) in postmenopausal groups. For CA125, the AUC was 0.81 (p < 0.001) in premenopausal and 0.671 (p = 0.002) in postmenopausal groups. Cut-off concentrations to predict lymph node metastasis: Premenopausal - HE4 = 52.95 pmol/l, CA125 = 69.45 U/ml; Postmenopausal - HE4 = 69.15pmol/l, CA125 = 21.45 U/ml. Combining enhanced CT imaging with HE4 and CA125 improved diagnostic accuracy compared to individual tests. In conclusion, the study offers valuable insights into the potential usefulness of HE4 and CA125, in conjunction with enhanced CT imaging, for diagnosing and predicting lymph node metastasis in patients with endometrial cancer.</p>","PeriodicalId":8962,"journal":{"name":"Bioinformation","volume":"20 11","pages":"1453-1460"},"PeriodicalIF":1.9,"publicationDate":"2024-11-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11953557/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143750935","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
BioinformationPub Date : 2024-11-30eCollection Date: 2024-01-01DOI: 10.6026/9732063002001608
Ruchi Singh, Jyotsana Rai, Akash Pathak, Nirendra Kumar Rai
{"title":"A study on the effect of fibromyalgia severity on sleep quality using inflammatory markers.","authors":"Ruchi Singh, Jyotsana Rai, Akash Pathak, Nirendra Kumar Rai","doi":"10.6026/9732063002001608","DOIUrl":"10.6026/9732063002001608","url":null,"abstract":"<p><p>Fibromyalgia syndrome (FMS) is a widespread musculoskeletal pain, often accompanied by fatigue and sleep disturbances. Poor sleep exacerbates inflammation and pain, potentially increasing levels of inflammatory markers. This study explored the effect of FMS severity on CRP levels, sleep quality and pain intensity. 89 FMS individuals were explored for FMS severity, pain and sleep quality. CRP levels in blood and erythrocyte sedimentation rate (ESR) were measured to assess inflammation. An increase in FMS severity was associated with an increase in CRP and ESR levels, pain intensity and sleep disturbances. However, a positive correlation between CRP levels and sleep quality indicates that Poor sleep quality in FMS may contribute to elevated CRP levels. Addressing sleep quality may mitigate the severity of FMS and its associated symptoms.</p>","PeriodicalId":8962,"journal":{"name":"Bioinformation","volume":"20 11","pages":"1608-1612"},"PeriodicalIF":1.9,"publicationDate":"2024-11-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11953530/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143750914","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}