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Antibiotic prophylaxis among Indian women undergoing cesarean sections. 印度剖宫产妇女的抗生素预防。
IF 1.9
Bioinformation Pub Date : 2025-04-30 eCollection Date: 2025-01-01 DOI: 10.6026/973206300210594
Bhavani Kaveti, Gadiparthi Anusha, Priyadarshini Ramesh, Madhurika Jalakam, Prashannalakshmi A, Reema Reji, Yagvalkya Sharma
{"title":"Antibiotic prophylaxis among Indian women undergoing cesarean sections.","authors":"Bhavani Kaveti, Gadiparthi Anusha, Priyadarshini Ramesh, Madhurika Jalakam, Prashannalakshmi A, Reema Reji, Yagvalkya Sharma","doi":"10.6026/973206300210594","DOIUrl":"10.6026/973206300210594","url":null,"abstract":"<p><p>Cesarean sections are associated with a high risk of postoperative infections, making timely and appropriate antibiotic prophylaxis essential. Hence, a six-month study of 100 patients found 85% compliance with recommended guidelines, with SSIs (Surgical site infections) occurring in 3% of timely cases versus 9% in delayed cases. Deviations, such as delayed administration or inappropriate antibiotic use, modestly increased infection risk. Key factors in reducing SSIs were timely antibiotic delivery and appropriate selection. Improved training, surveillance and audits are recommended to enhance compliance so as to ensure safe obstetric surgical practices.</p>","PeriodicalId":8962,"journal":{"name":"Bioinformation","volume":"21 4","pages":"594-598"},"PeriodicalIF":1.9,"publicationDate":"2025-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12236538/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144599257","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Current trends in telemedicine for chronic disease management. 慢性病管理远程医疗的当前趋势。
IF 1.9
Bioinformation Pub Date : 2025-04-30 eCollection Date: 2025-01-01 DOI: 10.6026/973206300210587
Navaneeth Ranjith, Sree Nithish Kanna Baskaran, Saranya R, Aswin Ganesan, Ranjani Kanakaraj, Gajalakshmi S, Siraj Muhammad Shafy, Akshay Sureshkumar Nair
{"title":"Current trends in telemedicine for chronic disease management.","authors":"Navaneeth Ranjith, Sree Nithish Kanna Baskaran, Saranya R, Aswin Ganesan, Ranjani Kanakaraj, Gajalakshmi S, Siraj Muhammad Shafy, Akshay Sureshkumar Nair","doi":"10.6026/973206300210587","DOIUrl":"10.6026/973206300210587","url":null,"abstract":"<p><p>Telemedicine is becoming a transformative tool for managing chronic diseases. Known literature data emphasizes the effectiveness and accessibility of telemedicine and its impact on patient outcomes. Thus, the foundation for advancing the role of telemedicine in chronic disease management for improving healthcare accessibility and quality of life is imperative.</p>","PeriodicalId":8962,"journal":{"name":"Bioinformation","volume":"21 4","pages":"587-593"},"PeriodicalIF":1.9,"publicationDate":"2025-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12236584/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144599265","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Molecular modelling and docking analysis of a modelled trmB protein from Pseudomonas aeruginosa with selected chemical compounds. 铜绿假单胞菌trmB蛋白模型的分子建模及与选定化合物的对接分析。
IF 1.9
Bioinformation Pub Date : 2025-04-30 eCollection Date: 2025-01-01 DOI: 10.6026/973206300210657
Sakshi Bhati, Imteyaz Qamar, Nagendra Singh
{"title":"Molecular modelling and docking analysis of a modelled <i>trmB</i> protein from <i>Pseudomonas aeruginosa</i> with selected chemical compounds.","authors":"Sakshi Bhati, Imteyaz Qamar, Nagendra Singh","doi":"10.6026/973206300210657","DOIUrl":"10.6026/973206300210657","url":null,"abstract":"<p><p>Antimicrobial resistance (AMR) threatens global health with rising antibiotic-resistant infections, requiring novel antimicrobial targets. Therefore, it is of interest to report the molecular modeling and docking analysis <i>trmB</i> from <i>Pseudomonas aeruginosa</i> with suitable compounds. We show two compounds (5136 and 9865603) from the chemical library have optimal binding with the modelled <i>trmB</i> from <i>Pseudomonas aeruginosa</i> for further consideration.</p>","PeriodicalId":8962,"journal":{"name":"Bioinformation","volume":"21 4","pages":"657-664"},"PeriodicalIF":1.9,"publicationDate":"2025-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12236524/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144599281","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Cytotoxic and apoptotic effects of novel phytochemical extracts on oral squamous cell carcinoma cells. 新型植物化学提取物对口腔鳞状细胞癌细胞的细胞毒性和凋亡作用。
IF 1.9
Bioinformation Pub Date : 2025-04-30 eCollection Date: 2025-01-01 DOI: 10.6026/973206300210801
Sweta Singh, Nishita Anthwal, Ankur Joshi, Rajni Saini, Vipin Arora, Abhishek Moharana
{"title":"Cytotoxic and apoptotic effects of novel phytochemical extracts on oral squamous cell carcinoma cells.","authors":"Sweta Singh, Nishita Anthwal, Ankur Joshi, Rajni Saini, Vipin Arora, Abhishek Moharana","doi":"10.6026/973206300210801","DOIUrl":"10.6026/973206300210801","url":null,"abstract":"<p><p>The oral squamous cell carcinoma has inadequate treatment methods. Therefore, it is of interest to investigate the effect of new phytochemical extracts on both cell death and programmed cell death of OSCC cells. The phytochemical extracts tested at different concentrations produced a decrease in cell survival which dropped from 85% to 40% (p < 0.05) and led to increased apoptotic death from 15% to 60%. Caspase-3 activation tests showed both apoptotic changes and morphological developments at the cellular level for further consideration through <i>in vivo</i> analysis.</p>","PeriodicalId":8962,"journal":{"name":"Bioinformation","volume":"21 4","pages":"801-804"},"PeriodicalIF":1.9,"publicationDate":"2025-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12236559/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144599266","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effect of bioceramic sealers in enhancing root canal healing. 生物陶瓷封闭剂促进根管愈合的效果。
IF 1.9
Bioinformation Pub Date : 2025-04-30 eCollection Date: 2025-01-01 DOI: 10.6026/973206300210866
Shankar S, Rajul Vivek, Nitu Chaubey, Vinay Rao, Sagar Hiwale, Nandhita S K
{"title":"Effect of bioceramic sealers in enhancing root canal healing.","authors":"Shankar S, Rajul Vivek, Nitu Chaubey, Vinay Rao, Sagar Hiwale, Nandhita S K","doi":"10.6026/973206300210866","DOIUrl":"10.6026/973206300210866","url":null,"abstract":"<p><p>Root canal treatment requires optimal sealing to stop infection from recurring while aiding the healing processes. Therefore, it is of interest to examine the analysis of bioceramic and conventional dental sealants using 100 patient samples within a period of six months. Bioceramic sealers achieved better results since 90% of patients experienced periapical healing compared to 75% in the conventional group. The bioceramic group excelled in both reducing pain and attaining superior radiographic sealing quality. Thus, healing progresses better when dentists use bioceramic sealers which enhance root canal therapy according to expert recommendations.</p>","PeriodicalId":8962,"journal":{"name":"Bioinformation","volume":"21 4","pages":"866-869"},"PeriodicalIF":1.9,"publicationDate":"2025-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12236570/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144599272","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Penetration depth of different irrigants in simulated lateral canalsPenetration depth of different irrigants in simulated lateral canals. 不同灌溉水在模拟侧管中的渗透深度不同灌溉水在模拟侧管中的渗透深度。
IF 1.9
Bioinformation Pub Date : 2025-04-30 eCollection Date: 2025-01-01 DOI: 10.6026/973206300210797
Sonali Bansal, Niladri Maiti, Tejal Gowda, Ravi Ranjan Sinha, Sidhartha S P Behera, Rajshekhar Chatterjee
{"title":"Penetration depth of different irrigants in simulated lateral canalsPenetration depth of different irrigants in simulated lateral canals.","authors":"Sonali Bansal, Niladri Maiti, Tejal Gowda, Ravi Ranjan Sinha, Sidhartha S P Behera, Rajshekhar Chatterjee","doi":"10.6026/973206300210797","DOIUrl":"10.6026/973206300210797","url":null,"abstract":"<p><p>Proper root canal disinfection needs lateral canals to receive irrigant penetration so that microbial biofilms can be eliminated. Therefore, it is of interest to investigate using confocal laser scanning microscopy how deep NaOCl (5.25%) and CHX (2%) and EDTA (17%) solution penetrated into 60 extracted teeth. NaOCl demonstrated the longest penetration depth at 750 ± 50 µm and trialed EDTA at 620 ± 40 µm and CHX with 480 ± 35 µm penetration depths. Better diffusion is seen in the coronal section (p < 0.05). Thus, NaOCl is the best irrigating agent for disinfecting lateral canals.</p>","PeriodicalId":8962,"journal":{"name":"Bioinformation","volume":"21 4","pages":"797-800"},"PeriodicalIF":1.9,"publicationDate":"2025-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12236557/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144599285","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effectiveness of a self-instructional module on home care management of diabetes mellitus among adults. 成人糖尿病家庭护理管理自学模块的有效性。
IF 1.9
Bioinformation Pub Date : 2025-04-30 eCollection Date: 2025-01-01 DOI: 10.6026/973206300210578
Beula S S, Siva Subramanian N, Mahalakshmi B, Patel Princekumar Satishkumar, Patel Pransi Baldevbhai, Patel Mihir Jigarkumar, Karan Vikrambhai Chaudhary, Roshankumar Dineshbhai Patel, Patel Sakshi Maheshkumar, Patel Meshva Rajeshkumar
{"title":"Effectiveness of a self-instructional module on home care management of diabetes mellitus among adults.","authors":"Beula S S, Siva Subramanian N, Mahalakshmi B, Patel Princekumar Satishkumar, Patel Pransi Baldevbhai, Patel Mihir Jigarkumar, Karan Vikrambhai Chaudhary, Roshankumar Dineshbhai Patel, Patel Sakshi Maheshkumar, Patel Meshva Rajeshkumar","doi":"10.6026/973206300210578","DOIUrl":"10.6026/973206300210578","url":null,"abstract":"<p><p>The effectiveness of a self-instructional module (SIM) on knowledge regarding home care management of diabetes mellitus among adults in Visnagar is of interest. A pre-experimental one-group pre-test and post-test design was used, with 50 diabetic patients selected through non-probability convenience sampling. A structured questionnaire assessed knowledge before and after the intervention. The results showed a significant improvement in post-test scores, demonstrating the effectiveness of SIM in enhancing diabetes-related knowledge. The mean pre-test score was 12.5 ± 3.2, which increased to 20.8 ± 2.8 post-intervention (p < 0.05). Thus, SIM is an effective tool for diabetes education, especially in low-resource settings and can significantly improve self-care practices and disease management among diabetic patients.</p>","PeriodicalId":8962,"journal":{"name":"Bioinformation","volume":"21 4","pages":"578-582"},"PeriodicalIF":1.9,"publicationDate":"2025-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12236539/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144599301","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Fourier transform in Bioinformatics and Biomedicine. 傅里叶变换在生物信息学和生物医学中的应用。
IF 1.9
Bioinformation Pub Date : 2025-04-30 eCollection Date: 2025-01-01 DOI: 10.6026/973206300210575
Paul Shapshak
{"title":"Fourier transform in Bioinformatics and Biomedicine.","authors":"Paul Shapshak","doi":"10.6026/973206300210575","DOIUrl":"10.6026/973206300210575","url":null,"abstract":"<p><p>This brief paper provides an overview of the application of Fourier Transforms to bioinformatics and biomedicine. Fourier analysis and transforms have been applied extensively to fields including for example, cosmology, engineering and physics. In the fields of Bioinformatics and Biomedicine less has been accomplished. The application of Fourier analysis will amplify the accuracy and insights of these fields. Fourier analysis will also widen their scopes. This will improve understanding of basic fundamental biochemical and molecular processes and will assist in improving the accuracy and speed of medical and clinical diagnosis and treatments.</p>","PeriodicalId":8962,"journal":{"name":"Bioinformation","volume":"21 4","pages":"575-577"},"PeriodicalIF":1.9,"publicationDate":"2025-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12236583/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144599309","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Analysis of soft and hard tissue changes following anterior segmental bi-jaw orthognathic surgery. 前节段双颌正颌手术后软硬组织变化分析。
IF 1.9
Bioinformation Pub Date : 2025-04-30 eCollection Date: 2025-01-01 DOI: 10.6026/973206300210695
Kuldeep Pal, Swati Tiwari, Sumit Patidar, Rashmi Rai, Anurag Tripathi
{"title":"Analysis of soft and hard tissue changes following anterior segmental bi-jaw orthognathic surgery.","authors":"Kuldeep Pal, Swati Tiwari, Sumit Patidar, Rashmi Rai, Anurag Tripathi","doi":"10.6026/973206300210695","DOIUrl":"10.6026/973206300210695","url":null,"abstract":"<p><p>Medical experts often carry out anterior segmental bi-jaw orthognathic surgery to address dentofacial abnormalities affecting both the maxilla and mandible. Therefore, it is of interest to study tissue alterations from both quantitative and qualitative viewpoints after the use of this specific approach. Prospective clinical evaluations on 20 surgical patients aged 18 to 30 years who had undergone anterior segmental bi-jaw orthognathic surgery. A lateral cephalometric examination was carried out on the same individuals before to treatment, with further imaging performed during the six-month postoperative follow-up. Orthognathic surgery, encompassing anterior segmental bi-jaw treatment, delivers major improvements in facial aesthetics by inducing desirable adjustments in both hard and soft tissues.</p>","PeriodicalId":8962,"journal":{"name":"Bioinformation","volume":"21 4","pages":"695-698"},"PeriodicalIF":1.9,"publicationDate":"2025-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12236579/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144599256","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Assessment of intestinal obstruction: Clinical presentation, pathological findings and management. 肠梗阻的评估：临床表现、病理表现和处理。
IF 1.9
Bioinformation Pub Date : 2025-04-30 eCollection Date: 2025-01-01 DOI: 10.6026/973206300210892
Bhupesh Kushram, Archana Kori, Dinesh Kumar Thakur, Abhay Kumar, Mahendra Singh
{"title":"Assessment of intestinal obstruction: Clinical presentation, pathological findings and management.","authors":"Bhupesh Kushram, Archana Kori, Dinesh Kumar Thakur, Abhay Kumar, Mahendra Singh","doi":"10.6026/973206300210892","DOIUrl":"10.6026/973206300210892","url":null,"abstract":"<p><p>Evaluating the clinical presentation of intestinal obstruction along with its pathological findings is crucial for accurate diagnosis and timely intervention. A total of 100 patients presenting with signs and symptoms of acute or subacute intestinal obstruction were included, and their detailed clinical histories, physical examinations, laboratory investigations, and radiological assessments were recorded. Intraoperative findings and histopathological results were correlated to identify the most common etiologies and to assess clinical outcomes. Follow-ups were done for at least six weeks post-discharge. A combined clinico-pathological approach is instrumental in effectively diagnosing and managing intestinal obstruction. Early detection, prompt surgical intervention when indicated, and appropriate postoperative care is essential to reduce morbidity and mortality.</p>","PeriodicalId":8962,"journal":{"name":"Bioinformation","volume":"21 4","pages":"892-896"},"PeriodicalIF":1.9,"publicationDate":"2025-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12236547/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144599259","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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