睡眠呼吸暂停严重程度对左心室重构的影响。

IF 1.9
Bioinformation Pub Date : 2025-06-30 eCollection Date: 2025-01-01 DOI:10.6026/973206300211593
Vutukuri Kiranmai, Amoolya Rao Amaravadhi, Vaishnavi Jamched, Kosmita Karki, Navneeth Jayaprakash, Angel Pratapsingh Chavan, James Joseph Rajan
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引用次数: 0

摘要

睡眠呼吸暂停是一种常见但常被忽视的疾病,与心血管功能障碍密切相关,尤其是左心室重构。这项纵向研究评估了由呼吸暂停低通气指数(AHI)定义的睡眠呼吸暂停严重程度组的左室结构和功能随时间的变化。连续超声心动图评价显示,中度至重度睡眠呼吸暂停与左室质量指数升高、收缩和舒张功能障碍显著相关。更高的AHI严重程度和缺乏治疗与更严重的左室损害有关。这些结果强调早期诊断和管理睡眠呼吸暂停的必要性,以减少其对心脏的长期影响。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Impact of sleep apnea severity on left ventricular remodelling.

Sleep apnea is a common but often overlooked condition strongly associated with cardiovascular dysfunction, particularly left ventricular (LV) remodeling. This longitudinal study assessed changes in LV structure and function over time across sleep apnea severity groups defined by the apnea-hypopnea index (AHI). Serial echocardiographic evaluations revealed that moderate-to-severe sleep apnea was significantly correlated with increased LV mass index, systolic and diastolic dysfunction. Greater AHI severity and lack of treatment were linked to more progressive LV impairment. These results emphasize the need for early diagnosis and management of sleep apnea to reduce its long-term cardiac impact.

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Bioinformation
Bioinformation MATHEMATICAL & COMPUTATIONAL BIOLOGY-
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