Bioinformation最新文献_第2页

Effect of ionic tooth brushes on gingivitis among Indian patients undergoing orthodontic treatment. 离子牙刷对印度正畸患者牙龈炎的影响。

IF 1.9

Bioinformation Pub Date : 2024-11-30 eCollection Date: 2024-01-01 DOI: 10.6026/9732063002001645

Simran Saluja, Rupali Kalsi, Kumar Saurav, Gunjan Gupta, Sachit Anand Arora, Vandana K L, Shivesh Kumar Mishra

引用次数: 0

Effect of novel IL-8 gene mutation on its protein structure and stability among ovarian cancer patients in Saudi Arabia. 沙特阿拉伯卵巢癌患者IL-8基因突变对其蛋白结构和稳定性的影响

IF 1.9

Bioinformation Pub Date : 2024-11-30 eCollection Date: 2024-01-01 DOI: 10.6026/9732063002001671

Absarul Haque, Ghazanfar Ali Baig, Abdulelah Saleh Alshawli, Khalid Hussain Wali Sait, Hani S H Mohammed Ali, Hesham Khalid Hussain Sait, Fehmida Bibi, Peter Natesan Pushparaj, Mahmood Rasool, Muhammad Imran Naseer

{"title":"Effect of novel IL-8 gene mutation on its protein structure and stability among ovarian cancer patients in Saudi Arabia.","authors":"Absarul Haque, Ghazanfar Ali Baig, Abdulelah Saleh Alshawli, Khalid Hussain Wali Sait, Hani S H Mohammed Ali, Hesham Khalid Hussain Sait, Fehmida Bibi, Peter Natesan Pushparaj, Mahmood Rasool, Muhammad Imran Naseer","doi":"10.6026/9732063002001671","DOIUrl":"10.6026/9732063002001671","url":null,"abstract":"Despite advancements in therapeutics, early diagnosis of ovarian cancer (OC) remains a challenge due to its asymptomatic progression and it is often diagnosed at an advanced stage. Interleukin-8 (IL-8), a pro-inflammatory chemokine with angiogenic activity, plays a pivotal role in inflammation and carcinogenesis. Therefore, it is of interest to investigate the association between IL-8 polymorphisms and OC risk. A novel non-synonymous SNP (nsSNP, c.193G>A; p.Glu65Leu) was identified in exon 2 of the IL-8 gene in 5 patients, 3 with stage III and 2 with stage II tumor. Structural analysis suggested that the p.Glu65Leu mutation alters the IL-8 protein conformation showing functional impairment. Thus, data shows that IL-8 c.193 G >A (Glu65Leu) polymorphism may contribute to tumor susceptibility. However, further studies are warranted to understand the role of IL-8 polymorphism in OC.","PeriodicalId":8962,"journal":{"name":"Bioinformation","volume":"20 11","pages":"1671-1677"},"PeriodicalIF":1.9,"publicationDate":"2024-11-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11953556/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143751005","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Knowledge and perception of cancer screening tests among Indian community. 印度社区对癌症筛查测试的认识和认知。

IF 1.9

Bioinformation Pub Date : 2024-11-30 eCollection Date: 2024-01-01 DOI: 10.6026/9732063002001635

Sadaf Kibria, Soofia Firdaus, Mahima Srivastava, Sushant Kumar Sharma, Md Khalid Tanweer, Tushar Saini, Tauseef Kibria

{"title":"Knowledge and perception of cancer screening tests among Indian community.","authors":"Sadaf Kibria, Soofia Firdaus, Mahima Srivastava, Sushant Kumar Sharma, Md Khalid Tanweer, Tushar Saini, Tauseef Kibria","doi":"10.6026/9732063002001635","DOIUrl":"10.6026/9732063002001635","url":null,"abstract":"Health authorities can enhance the success of health screening programs and promotional campaigns by measuring the level of community awareness about cancer screening. Therefore, the primary purpose of this research was to evaluate the general population's understanding of cancer and its prevention in India. From January to June of 2023, a large-scale cross-sectional survey was conducted in India to gauge the general population's opinion on cancer screening. Researchers used a computerised, pre-structured questionnaire to collect data after reviewing the primary sources extensively. Digital surveying was used to disseminate the questionnaire, protecting the confidentiality and anonymity of all respondents. The Pearson chi-square test and the exact probability test were used to analyse the data in this study to uncover any underlying links in the study's sparse frequency distributions. The study's findings underscore the urgent need for increased education on cancer, cancer screening and risk reduction initiatives. Participants with chronic diseases and a cancer history in their families showed significantly higher levels of awareness, highlighting the potential for targeted education and screening programs to improve public health.","PeriodicalId":8962,"journal":{"name":"Bioinformation","volume":"20 11","pages":"1635-1640"},"PeriodicalIF":1.9,"publicationDate":"2024-11-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11953554/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143750831","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Awareness, perception and attitude towards nano-dentistry among post-graduates from Rajasthan, India. 印度拉贾斯坦邦研究生对纳米牙科的认识、感知和态度。

IF 1.9

Bioinformation Pub Date : 2024-11-30 eCollection Date: 2024-01-01 DOI: 10.6026/9732063002001537

Saloni Kanodia, Abhishek Khairwa, Soumyaranjan Nanda, Shubhangi Pareek, Marium Mishra, Shreeyam Mohapatra, Pratik Surana

引用次数: 0

Effect of strip type denture adhesives on Candida species colonization in complete denture wearing patients. 条带型义齿粘接剂对全口义齿患者念珠菌定植的影响。

IF 1.9

Bioinformation Pub Date : 2024-11-30 eCollection Date: 2024-01-01 DOI: 10.6026/9732063002001613

Sameer Chauhan, Paranjay Prajapati, Pritha Negi

{"title":"Effect of strip type denture adhesives on Candida species colonization in complete denture wearing patients.","authors":"Sameer Chauhan, Paranjay Prajapati, Pritha Negi","doi":"10.6026/9732063002001613","DOIUrl":"10.6026/9732063002001613","url":null,"abstract":"The present study was planned to evaluate the influence of strip of denture adhesive on oral microflora, mainly Candida species in the participants who were instructed to use Super Polygrip Comfort Seal Strips denture adhesive for 14 days of trial period. 24 completely edentulous patients treated with complete denture were randomly divided into following - Control and Test group (12 each group). Test group was prescribed a strip denture adhesive and instructed to use it for 14 days. Samples of saliva were collected from all participants (both control and test groups) on 0 day, 7th and 14th day. Collected samples were diluted with standard protocol and coated on culture media of Sabouraud dextrose agar and incubated for 48 hours at 37°C. The CFU/ml was analyzed from both groups. Collected data then analyzed statistically with Mann - Whitney U - Test where α kept at ≤ 5%. No significant statistical difference was found between the control and the test group after the testing duration of 14 days. Thus, results suggested that strip denture adhesive did not have any influence on the colonization of Candida species during 14 days of test period and it is safe for the use in complete denture wearing patients.","PeriodicalId":8962,"journal":{"name":"Bioinformation","volume":"20 11","pages":"1613-1618"},"PeriodicalIF":1.9,"publicationDate":"2024-11-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11953544/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143751008","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Unraveling the amygdala: A review of its anatomy and functions. 解开杏仁核：对其解剖和功能的回顾。

IF 1.9

Bioinformation Pub Date : 2024-11-30 eCollection Date: 2024-01-01 DOI: 10.6026/9732063002001588

K S V Angu Bala Ganesh, Payal Panda, Amit H Makwana, Prarthana Kalerammana Gopalakrishna, Kandula Prameela Rani, Thirupathirao Vishnumukkala

引用次数: 0

Prescribing trends and rational drug use patterns in cardiovascular patients: A cross-sectional observational study. 心血管患者的处方趋势和合理用药模式：一项横断面观察性研究。

IF 1.9

Bioinformation Pub Date : 2024-11-30 eCollection Date: 2024-01-01 DOI: 10.6026/9732063002001582

Radhika Chikatipalli, Anitha Kuttiappan, Sanjeev Kumar, Vishali R, Priyanka Kujur, Afsal N A, Poojitha N R, Santenna Chenchula

{"title":"Prescribing trends and rational drug use patterns in cardiovascular patients: A cross-sectional observational study.","authors":"Radhika Chikatipalli, Anitha Kuttiappan, Sanjeev Kumar, Vishali R, Priyanka Kujur, Afsal N A, Poojitha N R, Santenna Chenchula","doi":"10.6026/9732063002001582","DOIUrl":"10.6026/9732063002001582","url":null,"abstract":"Cardiovascular diseases (CVDs), encompassing conditions like coronary artery disease, hypertension and ischemic heart disease, are highly prevalent worldwide. This study analyzed prescribing trends and treatment appropriateness in CVD patients, focusing on adherence to guidelines, essential medicine use and generic drug prescriptions. A cross-sectional observational study was conducted on CVD-diagnosed patients. Data on prescribed medications-including drug classes, generic prescriptions and adherence to the Essential Drug List (EDL)-were collected and analyzed using IBM SPSS version 26.0. The most frequently prescribed drug classes included antiplatelets, diuretics and hypolipidemics. Aspirin was the most commonly prescribed medication (58.1%), followed by furosemide (36.5%), amlodipine (32.4%) and rosuvastatin (24.3%). Statins and calcium channel blockers were prescribed more often than angiotensin II receptor blockers and beta-blockers. On average, 13.2 drugs were prescribed per patient, with only 28.8% prescribed generically. Furthermore, 47.3% of medications were on the EDL. This study highlights the high prevalence of CVDs and the common drug classes prescribed to manage them. These findings provide important insights into current prescribing trends, particularly the frequent use of anti-hypertensive, antiplatelets, diuretics and hypolipidemics and suggest areas for optimizing medication management in this population. Additionally, there is a need to better manage polypharmacy in CVD patients.","PeriodicalId":8962,"journal":{"name":"Bioinformation","volume":"20 11","pages":"1582-1587"},"PeriodicalIF":1.9,"publicationDate":"2024-11-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11953553/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143750925","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Care and support for women during labour: A review. 对分娩期间妇女的照顾和支助：综述。

IF 1.9

Bioinformation Pub Date : 2024-11-30 eCollection Date: 2024-01-01 DOI: 10.6026/9732063002001598

Shankar Shanmugam Rajendran, Desigamani K, Bama Ramu

引用次数: 0

Carl Gustav Jung: Paradigms and extra-terrestrial intelligence. 卡尔·古斯塔夫·荣格：范式和外星智慧。

IF 1.9

Bioinformation Pub Date : 2024-11-30 eCollection Date: 2024-01-01 DOI: 10.6026/9732063002001524

Paul Shapshak

引用次数: 0

Effect of hypochlorous acid in open wound healing. 次氯酸对开放性伤口愈合的影响。

IF 1.9

Bioinformation Pub Date : 2024-11-30 eCollection Date: 2024-01-01 DOI: 10.6026/9732063002001619

Spurgeon Raj Jalem, Purimitla Usharani

{"title":"Effect of hypochlorous acid in open wound healing.","authors":"Spurgeon Raj Jalem, Purimitla Usharani","doi":"10.6026/9732063002001619","DOIUrl":"10.6026/9732063002001619","url":null,"abstract":"Wound healing is a complex process involving multiple stages to restore the integrity and function of damaged tissues. Researchers are exploring the therapeutic potential of HOCl in treating infections and inflammatory conditions, given its efficacy in killing pathogens and modulating immune responses. The present study is a prospective study aimed to know the wound healing nature of HOCl on open wounds in patients attending out-patient department. The study was conducted for a period of one year Jan 2023 to Jan 2024 at Bliss Hospital, Hyderabad, Telangana district, India. Hypochlorous acid (Vida solutions, Pvt. Ltd) was used to irrigate the open wound. Among the 10 reported cases, three were females and seven were males. Most of the cases were reported from middle-age and old-age persons except one paediatric case of age 3 years a female girl. A male patient of age 72 years with co-morbidities diabetes and hypertension suffering with chronic wound on left leg for a period of 35 years because of thorn prick injury. The complete wound healing took nearly 15 weeks in this patient. The wound healing takes place 8 to 15 weeks maximum in all the 10 cases and the above findings concluded that, these features lead to a stabilized HOCl solution as an ideal wound care agent.","PeriodicalId":8962,"journal":{"name":"Bioinformation","volume":"20 11","pages":"1619-1622"},"PeriodicalIF":1.9,"publicationDate":"2024-11-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11953545/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143751000","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0