唾液MMP-9在OSCC检测和诊断中的作用:一项综合临床评估。

IF 1.9
Bioinformation Pub Date : 2025-06-30 eCollection Date: 2025-01-01 DOI:10.6026/973206300211680
Pranav Manek, Vijayta Singh, Gajendra Singh Sisodia, Indu Tomar, Dax Abraham, Parul Agarwal
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引用次数: 0

摘要

采用酶联免疫吸附试验(ELISA)检测鳞状细胞癌患者唾液基质金属蛋白酶-9 (MMP-9)水平。60名研究参与者中有30人确诊为口腔鳞状细胞癌,其余20人为健康对照。离心提取唾液MMP-9水平,ELISA检测。将口腔鳞状细胞癌患者与对照组的结果进行比较。口腔鳞状细胞癌患者的平均唾液MMP-9水平明显高于健康受试者(p
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Role of salivary MMP-9 in OSCC detection and diagnosis: A comprehensive clinical assessment.

An Enzyme-Linked Immunosorbent Assay (ELISA) to measure the salivary Matrix metalloproteinase-9 (MMP-9) levels among squamous cell carcinoma patients was used. Thirty of the sixty participants in the research had a verified diagnosis of oral SCC, whereas the remaining twenty were healthy controls. Salivary MMP-9 levels were extracted by centrifugation and measured using ELISA. The results were compared between oral SCC patients and controls. Participants with oral squamous cell carcinoma had considerably greater mean salivary MMP-9 levels than healthy subjects (p<0.05). Thus, individuals with oral squamous cell carcinoma have average salivary MMP-9 levels, and those with poorly differentiated oral squamous cell carcinoma have even higher levels.

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来源期刊
Bioinformation
Bioinformation MATHEMATICAL & COMPUTATIONAL BIOLOGY-
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