Neonatal umbilical cord blood bilirubin as a biomarker for hyperbilirubinemia required phototherapy.

IF 1.9
Bioinformation Pub Date : 2025-06-30 eCollection Date: 2025-01-01 DOI:10.6026/973206300211677
Madhav Shridharrao Kadam, Mohit Garg, Seema Sutay, Sandeep Singh Matreja, Priyadarshini Rangari, Amit Rangari
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Abstract

Jaundice is clinical condition characterized by transient deficiency of bilirubin conjugation, leading to neonatal hyperbilirubinemia. Therefore, it is of interest to assess cord blood bilirubin as a predictor for neonatal hyper-bilirubinemia (HB) needing phototherapy in full-term neonates. In 220 neonates with HB were assigned as cases and without HB as controls. The mean cord blood bilirubin level was 2.64±0.63 and total serum bilirubin estimated on 3rd day of life was 16.14±1.4. Umbilical cord blood bilirubin estimation is a non-invasive, economical and simple method of predicting subsequent neonatal hyper-bilirubinemia that can help clinicians for early discharge of normal neonates and follow-up in high-risk infants.

新生儿脐带血胆红素作为高胆红素血症的生物标志物需要光疗。
黄疸是一种以胆红素偶联性短暂缺乏为特征的临床疾病,可导致新生儿高胆红素血症。因此,评估脐带血胆红素作为需要光疗的足月新生儿高胆红素血症(HB)的预测因子是有意义的。220名患有HB的新生儿被指定为病例,而没有HB的新生儿被指定为对照组。出生第3天脐带血平均胆红素水平为2.64±0.63,血清总胆红素水平为16.14±1.4。脐带血胆红素测定是一种无创、经济、简便的预测新生儿高胆红素血症的方法,可以帮助临床医生对正常新生儿的早期出院和高危儿的随访。
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来源期刊
Bioinformation
Bioinformation MATHEMATICAL & COMPUTATIONAL BIOLOGY-
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