{"title":"Neonatal umbilical cord blood bilirubin as a biomarker for hyperbilirubinemia required phototherapy.","authors":"Madhav Shridharrao Kadam, Mohit Garg, Seema Sutay, Sandeep Singh Matreja, Priyadarshini Rangari, Amit Rangari","doi":"10.6026/973206300211677","DOIUrl":null,"url":null,"abstract":"<p><p>Jaundice is clinical condition characterized by transient deficiency of bilirubin conjugation, leading to neonatal hyperbilirubinemia. Therefore, it is of interest to assess cord blood bilirubin as a predictor for neonatal hyper-bilirubinemia (HB) needing phototherapy in full-term neonates. In 220 neonates with HB were assigned as cases and without HB as controls. The mean cord blood bilirubin level was 2.64±0.63 and total serum bilirubin estimated on 3rd day of life was 16.14±1.4. Umbilical cord blood bilirubin estimation is a non-invasive, economical and simple method of predicting subsequent neonatal hyper-bilirubinemia that can help clinicians for early discharge of normal neonates and follow-up in high-risk infants.</p>","PeriodicalId":8962,"journal":{"name":"Bioinformation","volume":"21 6","pages":"1677-1679"},"PeriodicalIF":1.9000,"publicationDate":"2025-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12449559/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Bioinformation","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.6026/973206300211677","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/1/1 0:00:00","PubModel":"eCollection","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
Jaundice is clinical condition characterized by transient deficiency of bilirubin conjugation, leading to neonatal hyperbilirubinemia. Therefore, it is of interest to assess cord blood bilirubin as a predictor for neonatal hyper-bilirubinemia (HB) needing phototherapy in full-term neonates. In 220 neonates with HB were assigned as cases and without HB as controls. The mean cord blood bilirubin level was 2.64±0.63 and total serum bilirubin estimated on 3rd day of life was 16.14±1.4. Umbilical cord blood bilirubin estimation is a non-invasive, economical and simple method of predicting subsequent neonatal hyper-bilirubinemia that can help clinicians for early discharge of normal neonates and follow-up in high-risk infants.