Bioinformation最新文献_第9页

Effect of genetic factors on root resorption after orthodontic treatment: A systematic review. 遗传因素对正畸治疗后牙根吸收影响的系统综述。

IF 1.9

Bioinformation Pub Date : 2024-10-31 eCollection Date: 2024-01-01 DOI: 10.6026/9732063002001321

Hesham Alsaigh, Abdulmajeed Mohammed Al Shujaa, Nuha Hussein Aliuwayed, Rawan Abdullah Alqahtani, Mariya Ibrahim Alibrahim, Areej Mohammad Wadaan, Rema Yousef Alomran

{"title":"Effect of genetic factors on root resorption after orthodontic treatment: A systematic review.","authors":"Hesham Alsaigh, Abdulmajeed Mohammed Al Shujaa, Nuha Hussein Aliuwayed, Rawan Abdullah Alqahtani, Mariya Ibrahim Alibrahim, Areej Mohammad Wadaan, Rema Yousef Alomran","doi":"10.6026/9732063002001321","DOIUrl":"https://doi.org/10.6026/9732063002001321","url":null,"abstract":"Orthodontic treatment is a widely used dental procedure aimed at correcting mal-alignments for improving oral aesthetics. However, a significant proportion of patient's undergoing orthodontic treatment experience root resorption. This is a complex phenomenon characterized by the loss of tooth root structure. Further, the etiology of root resorption is multifaceted with various factors contributing to its development. Moreover, genetic factors play a crucial role in predisposing individuals to root resorption. Therefore, it is of interest to review the effect of genetic factors on root resorption after orthodontic treatment. The link between certain genetic variants with an increased risk of root resorption in orthodontic patients is of interest to dentists. Known data shows that genetic variants in IL1B, IL-6, and P2RX7 genes contribute to the development of root resorption. Thus, hereditary variables have a substantial impact on the occurrence of root resorption in orthodontic patients. Hence, the need for genetic screening to detect individuals who are susceptible to root resorption is highly relevant. Furthermore, knowledge on genetic risk factors can provide valuable insights for creating customised treatment programmes and preventive measures to reduce the likelihood of root resorption.","PeriodicalId":8962,"journal":{"name":"Bioinformation","volume":"20 10","pages":"1321-1328"},"PeriodicalIF":1.9,"publicationDate":"2024-10-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11904145/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143646942","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Linking hearing loss with noise exposure at road traffics in India. 听力损失与印度道路交通噪音暴露之间的关系。

IF 1.9

Bioinformation Pub Date : 2024-10-31 eCollection Date: 2024-01-01 DOI: 10.6026/9732063002001211

Barkha Yadav, Abhay D Havle

引用次数: 0

Longitudinal assessment of cardio-respiratory fitness among Indian patients with type 2 diabetes mellitus. 印度2型糖尿病患者心肺健康的纵向评估。

IF 1.9

Bioinformation Pub Date : 2024-10-31 eCollection Date: 2024-01-01 DOI: 10.6026/9732063002001261

Sushmita Palia, Mounish Reddy, Shreya Seira Honarius, Madhurika Jalakam, Ruchi Kothari, Mayur Wanjari, Labdhi Sangoi, Ravi Sangoi

{"title":"Longitudinal assessment of cardio-respiratory fitness among Indian patients with type 2 diabetes mellitus.","authors":"Sushmita Palia, Mounish Reddy, Shreya Seira Honarius, Madhurika Jalakam, Ruchi Kothari, Mayur Wanjari, Labdhi Sangoi, Ravi Sangoi","doi":"10.6026/9732063002001261","DOIUrl":"https://doi.org/10.6026/9732063002001261","url":null,"abstract":"Type 2 Diabetes Mellitus (T2DM) is associated with many complications, including cardiovascular and autonomic dysfunctions. Cardiorespiratory fitness as estimated by maximal oxygen uptake (VO2 max) is a very powerful predictor of cardiovascular health. Therefore, it is of interest to measure the cardiorespiratory parameters in T2DM patients for diagnosing autonomic dysfunction and to follow the changes over time. Baseline and follow-up cardiorespiratory fitness parameters among patients of Central India suffering from T2DM and its effectiveness to lifestyle modifications for these parameters are done. This hospital-based longitudinal study was conducted on 600 patients between the age group of 30 and 65 years diagnosed with T2DM. Patients were recruited from the Sports Physiology Laboratory, Department of Physiology, Mahatma Gandhi Institute of Medical Sciences, Sevagram, Maharashtra. Baseline measurements of VO2 max, HRV, and other cardiorespiratory variables were taken with a motorized treadmill using Lab Chart. Then, lifestyle counselling was undertaken for the participants and the same parameters were reassessed one year later. Statistical package SPSS version 23 was used during data analysis. After one year of interventions, the improvements at the end of one year include those of VO2 max and HRV. The mean VO2 max improved from 25.4 ± 5.2 to 30.1 ± 4.8 ml/kg/min while the probability was less than 0.001. The main indices of HRV showed improved autonomic balance along with enhanced parasympathetic activity. Combining lifestyle interventions with regular monitoring of cardiorespiratory fitness and HRV can, indeed significantly improve cardiovascular health in T2DM patients. This study calls for the inclusion of fitness assessments in everyday clinical care for diabetes.","PeriodicalId":8962,"journal":{"name":"Bioinformation","volume":"20 10","pages":"1261-1265"},"PeriodicalIF":1.9,"publicationDate":"2024-10-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11904149/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143647147","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Side effects of oxytocin and carbetocin for mangement at third trimester. 妊娠晚期处理催产素和卡霉素的副作用。

IF 1.9

Bioinformation Pub Date : 2024-10-31 eCollection Date: 2024-01-01 DOI: 10.6026/9732063002001405

Akshay Anup Bahekar, Rajkumar P Patange, Yamini Patil

引用次数: 0

Aloe vera vs chlorhexidine in preventing alveolar osteitis. 芦荟与氯己定预防牙槽骨炎的比较。

IF 1.9

Bioinformation Pub Date : 2024-09-30 eCollection Date: 2024-01-01 DOI: 10.6026/973206300200993

Shruti Ajmera, Sunil Sharma, Amit Kumar Sharma, Vikram Sharma, S Meera Petchiammal, Shraddha Sinha

{"title":"Aloe vera vs chlorhexidine in preventing alveolar osteitis.","authors":"Shruti Ajmera, Sunil Sharma, Amit Kumar Sharma, Vikram Sharma, S Meera Petchiammal, Shraddha Sinha","doi":"10.6026/973206300200993","DOIUrl":"10.6026/973206300200993","url":null,"abstract":"Alveolar Osteitis (AO) is a common and painful complication following tooth extraction or surgical excision, necessitating early treatment to minimize costs, morbidity, and frequent dental visits. Chlorhexidine (CHX) is the most widely used antiseptic, while Aloe Vera, a natural herbal plant, is gaining popularity in dentistry due to its minimal side effects. This study aimed to evaluate the efficacy of normal saline, Aloe Vera, and chlorhexidine mouthwashes in reducing the incidence of AO after lower third molar surgery. In a randomized controlled trial, 150 patients were divided into three groups: Group 1 (Chlorhexidine Mouthwash), Group 2 (Aloe Vera Mouthwash), and Group 3 (Normal Saline, placebo). Postoperative assessments on the 2nd and 7th days measured Trismus Grading, VAS, Wound Dehiscence, and AO. The results showed no significant difference in the occurrence of AO and Trismus grading between groups (p = 0.031 and 0.78, respectively), but wound dehiscence significantly differed (p = 0.013). While the VAS score on the 2nd day showed no significant difference, by the 7th day, chlorhexidine demonstrated better pain reduction than Aloe Vera. Although both mouthwashes were effective in reducing AO, chlorhexidine was more effective in reducing wound dehiscence and pain by the 7th day post-surgery.","PeriodicalId":8962,"journal":{"name":"Bioinformation","volume":"20 9","pages":"993-997"},"PeriodicalIF":1.9,"publicationDate":"2024-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11795504/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143363584","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Artificial intelligence in the radiological diagnosis of cancer. 人工智能在癌症放射诊断中的应用。

IF 1.9

Bioinformation Pub Date : 2024-09-30 eCollection Date: 2024-01-01 DOI: 10.6026/9732063002001512

Bassam Alkhalifah

引用次数: 0

Clinical characterization, molecular and genomic sequencing analysis of SARS-Cov-2 during second wave at Raigarh, Chhattisgarh, India. 印度恰蒂斯加尔邦赖加尔第二波SARS-Cov-2的临床特征、分子和基因组测序分析

IF 1.9

Bioinformation Pub Date : 2024-09-30 eCollection Date: 2024-01-01 DOI: 10.6026/9732063002001059

Anubha Patel, Anuniti Mathias, Ashish Baghel, Ankita Kumari, Swati Kujur

{"title":"Clinical characterization, molecular and genomic sequencing analysis of SARS-Cov-2 during second wave at Raigarh, Chhattisgarh, India.","authors":"Anubha Patel, Anuniti Mathias, Ashish Baghel, Ankita Kumari, Swati Kujur","doi":"10.6026/9732063002001059","DOIUrl":"10.6026/9732063002001059","url":null,"abstract":"The severe acute respiratory syndrome coronavirus-2 (SARS-Cov-2) has been changing continuously. This study was conducted to evaluate clinical characteristics, Molecular analysis & Genomic sequencing of SARS-Cov-2 during second wave in Raigarh district, Chhattisgarh, India. This study evaluated 13402 breakthrough cases of COVID -19. The laboratory obtained the nasopharyngeal/oropharyngeal swabs (NPS/OPS) of SARS-CoV-2 patients who tested positive by real-time RT-PCR, together with clinical and demographic information. Next generation sequencing (NGS) was used to sequence these clinical specimens in order to identify nucleotide changes in the SARS-CoV-2 genome from these strains. In the study population, variants of concern (VOCs) and other variations were looked for. Clinical severity was mild in 47.05% patients with mutational variants; while 52.94% patient's clinical severity was moderate. Delta (B.1.617.2) was the most common VOC detected. Among non VOC variants, AY.4 and AY.12 variants were most commonly detected. Envelope (E) gene and RNA-dependent RNA polymerase (RdRp) mutation were most commonly observed.","PeriodicalId":8962,"journal":{"name":"Bioinformation","volume":"20 9","pages":"1059-1064"},"PeriodicalIF":1.9,"publicationDate":"2024-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11795479/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143363242","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Early diagnosis of oral submucous fibrosis using salivary 8-OHDG and 8-Isoprostane. 唾液8-OHDG和8-异前列腺素对口腔黏膜下纤维化的早期诊断。

IF 1.9

Bioinformation Pub Date : 2024-09-30 eCollection Date: 2024-01-01 DOI: 10.6026/9732063002001042

Bireswar Roy, Shaili Ghosh, Ss Mohamed Abdulcader Riyaz, Madhvika Patidar, Urmi Mehta, Priya Agarwal, Pushkar Gupta

{"title":"Early diagnosis of oral submucous fibrosis using salivary 8-OHDG and 8-Isoprostane.","authors":"Bireswar Roy, Shaili Ghosh, Ss Mohamed Abdulcader Riyaz, Madhvika Patidar, Urmi Mehta, Priya Agarwal, Pushkar Gupta","doi":"10.6026/9732063002001042","DOIUrl":"10.6026/9732063002001042","url":null,"abstract":"Oral submucous fibrosis (OSMF) is a condition that may be cancerous. The prognosis of OSMF is determined by a number of biomarkers, including 8-hydroxy 2' de-oxy-guanosine and 8-isoprostane. It is possible to assess the levels of 8-OHdG and 8-isoprostane in blood and saliva. Therefore, it is of interest to estimate salivary 8-OHdG and 8-isoprostane levels in order to diagnose oral submucous fibrosis. A sample size of 40 was divided into two groups with 20 samples in each, i.e., Group I - Healthy group (gutka consumers without any lesion) and Group II -Test (gutka consumers with OSMF). Samples of serum and saliva were taken from each group. Then samples were centrifuged for 15-20 minutes at 1000 RPM and 2-8°C. The resulting supernatant was pipetted out into labelled Eppendorf tubes in a volume of 1.5 ml, and it was then kept at 80°C. 8-OHdG and 8-isoprostane concentrations in various samples were determined using the ELISA technique. Serum's 8-OHdG content was considerably lower than saliva sample (P-value <0.05). The test group exhibited increased concentrations of 8-OHdG and 8-isoprostane in both saliva and serum samples when compared to the control group. 8-OHdG and 8-isoprostane can be utilised to diagnoses of OSMF.","PeriodicalId":8962,"journal":{"name":"Bioinformation","volume":"20 9","pages":"1042-1045"},"PeriodicalIF":1.9,"publicationDate":"2024-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11795467/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143363328","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Mental health characteristics of re-entering dropout Indian students. 印度辍学生再入学的心理健康特征。

IF 1.9

Bioinformation Pub Date : 2024-09-30 eCollection Date: 2024-01-01 DOI: 10.6026/9732063002001034

Baskaran M

{"title":"Mental health characteristics of re-entering dropout Indian students.","authors":"Baskaran M","doi":"10.6026/9732063002001034","DOIUrl":"10.6026/9732063002001034","url":null,"abstract":"Education plays a pivotal role in shaping individual development and societal progress, yet dropout rates remain a significant challenge, particularly in developing countries like India. Dropout decisions often stem from complex social, economic and psychological factors, impacting students' mental health. This comparative descriptive study assessed and compared the mental health characteristics of 30 re-entering dropout students and 30 regular students from Integral Coach Factory (ICF) Hr. Sec. School, Ayanavaram, Chennai. Data collection utilized a structured questionnaire capturing demographic variables and the modified Abraham and Prasanna Mental Health Characteristics Scale. Re-entering dropout students exhibited lower mental health scores across physical, intellectual, familial, social, and psychological dimensions compared to regular students (p < 0.001). Significant associations were observed between mental health and father's education level among re-entering dropouts (p < 0.001), emphasizing its influence on well-being The study underscores disparities in mental health between re-entering dropout students and their peers, highlighting the need for targeted interventions and supportive environments in educational settings. Addressing these disparities can enhance overall well-being and academic success among re-entering dropout students.","PeriodicalId":8962,"journal":{"name":"Bioinformation","volume":"20 9","pages":"1034-1037"},"PeriodicalIF":1.9,"publicationDate":"2024-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11795483/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143363427","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Optimization and characterisation of water based keratin nanoparticles with Nigella sativa seed extract. 黑穗槐种子提取物水基角蛋白纳米颗粒的优化与表征。

IF 1.9

Bioinformation Pub Date : 2024-09-30 eCollection Date: 2024-01-01 DOI: 10.6026/973206300200957

Lawrance Antonysamy, Leema Rose Mary Devasahayam, Saradhadevi Muthukrishnan, Senthamizhselvan Anbazhagan, Marie Arockianathan Pushpam

{"title":"Optimization and characterisation of water based keratin nanoparticles with Nigella sativa seed extract.","authors":"Lawrance Antonysamy, Leema Rose Mary Devasahayam, Saradhadevi Muthukrishnan, Senthamizhselvan Anbazhagan, Marie Arockianathan Pushpam","doi":"10.6026/973206300200957","DOIUrl":"10.6026/973206300200957","url":null,"abstract":"Drug delivery technologies have been proven to improve treatment outcomes in many ways by enriching curative efficacy, reducing toxicity, increasing patient compliance and enabling entirely new type of medical treatments. In this study, keratin nanoparticles (KNPs) were prepared from chicken feathers and loaded with Nigella sativa seed extract (NSSE-KNPs) by adsorption method using doubled distilled water without using cross linkers, organic solvents and surfactants. The prepared KNPs and NSSE-KNPs were characterized by Dynamic light scattering (DLS), X-ray diffraction study (XRD), Fourier transform infrared spectroscopy (FT-IR) and scanning electron microscopy (SEM). The Encapsulation efficiency (EE) and loading capacity (LC) of NSSE-KNPs was found to be 82% and 70 % respectively. The drug release profile showed that KNPs exhibited slight difference in both acidic (pH 4.4) and basic (pH 7.4) environment. The prepared water-based KNPs and NSSE-KNPs also exhibited narrow PDI value and good negative zeta potential. The morphology of the keratin nanoparticles and Nigella sativa loaded keratin nanoparticles showed solid spheres, spherical and smooth shape distribution. The FTIR spectra revealed the possible hydrogen bonding formation after addition Nigella sativa seed extract to the keratin nanoparticles. In XRD analysis, both KNPs and NSSE-KNPs retained its chemical structure and crystallinity. The antibacterial effect was also observed for NSSE-KNPs against Staphylococcus aureus and Escherichia coli. Thus, the keratin nanoparticles loaded NSSE extract emerged as a potential candidate for future cancer treatment.","PeriodicalId":8962,"journal":{"name":"Bioinformation","volume":"20 9","pages":"957-965"},"PeriodicalIF":1.9,"publicationDate":"2024-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11795461/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143363438","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0