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Quantitative assessment of temporomandibular joint space in bruxers before and after occlusal splint therapy: A CBCT and MRI-based study. 牙合夹板治疗前后磨牙患者颞下颌关节间隙的定量评估：一项基于CBCT和mri的研究。
IF 1.9
Bioinformation Pub Date : 2025-06-30 eCollection Date: 2025-01-01 DOI: 10.6026/973206300211760
Chirag R Vaniya, Suvansh Gupta, Sourav Sen, Neha Bhadoria, Sadananda Hota, Sneha Sinha
{"title":"Quantitative assessment of temporomandibular joint space in bruxers before and after occlusal splint therapy: A CBCT and MRI-based study.","authors":"Chirag R Vaniya, Suvansh Gupta, Sourav Sen, Neha Bhadoria, Sadananda Hota, Sneha Sinha","doi":"10.6026/973206300211760","DOIUrl":"10.6026/973206300211760","url":null,"abstract":"<p><p>Occlusal splint therapy is a widely utilized conservative intervention for managing bruxism-associated myofascial pain and temporomandibular joint (TMJ) dysfunction. A prospective observational study evaluated 112 patients using Cone Beam Computed Tomography (CBCT) and Magnetic Resonance Imaging (MRI) at baseline and after six months of nocturnal splint therapy to assess osseous and soft tissue TMJ changes. Thus, occlusal splint therapy effectively promotes joint space normalization and soft tissue recovery in bruxism patients with TMJ myofascial pain, irrespective of age and gender differences.</p>","PeriodicalId":8962,"journal":{"name":"Bioinformation","volume":"21 6","pages":"1760-1765"},"PeriodicalIF":1.9,"publicationDate":"2025-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12449482/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145111934","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Prospective cohort study on recovery outcomes in elderly hip fracture patients using minimally invasive techniques. 应用微创技术对老年髋部骨折患者康复效果的前瞻性队列研究。
IF 1.9
Bioinformation Pub Date : 2025-06-30 eCollection Date: 2025-01-01 DOI: 10.6026/973206300211616
Priyanka Perumal, Harsh C Shingala, Shreyas Madagundanahalli Srinivasa, Rakshana Munusamy, Ajeet Saoji, Naman Dimpal Shah, Goutham Murugesan, Shoraf P
{"title":"Prospective cohort study on recovery outcomes in elderly hip fracture patients using minimally invasive techniques.","authors":"Priyanka Perumal, Harsh C Shingala, Shreyas Madagundanahalli Srinivasa, Rakshana Munusamy, Ajeet Saoji, Naman Dimpal Shah, Goutham Murugesan, Shoraf P","doi":"10.6026/973206300211616","DOIUrl":"10.6026/973206300211616","url":null,"abstract":"<p><p>Hip fractures in elderly patients are most often associated with a high degree of morbidity and mortality. The effectiveness of early intervention cannot be overemphasized. A prospective cohort study on elderly patients treated with minimally invasive surgical techniques to recover discusses issues on functional recovery, complications and length of hospital stay. Data were collected from 120 patients aged 65 years and above for a period of 12 months. The findings of the study indicated that minimally invasive techniques were associated with improved functional recovery and fewer complications than traditional methods, making them valuable in the care of elderly patients. Such results support the wider use of minimally invasive techniques in managing hip fractures among older populations.</p>","PeriodicalId":8962,"journal":{"name":"Bioinformation","volume":"21 6","pages":"1616-1619"},"PeriodicalIF":1.9,"publicationDate":"2025-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12449568/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145111936","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Survey on awareness of artificial intelligence in pediatric dentistry. 儿童牙科人工智能认知情况调查。
IF 1.9
Bioinformation Pub Date : 2025-06-30 eCollection Date: 2025-01-01 DOI: 10.6026/973206300211647
Shilpa S Naik, Jasmin Winner, Ishani Ratnaparkhi, Shirin Chavan, Mayuri Gorule, Ruchi Chaudhary
{"title":"Survey on awareness of artificial intelligence in pediatric dentistry.","authors":"Shilpa S Naik, Jasmin Winner, Ishani Ratnaparkhi, Shirin Chavan, Mayuri Gorule, Ruchi Chaudhary","doi":"10.6026/973206300211647","DOIUrl":"10.6026/973206300211647","url":null,"abstract":"<p><p>Artificial intelligence (AI) is transforming pediatric dentistry by improving diagnostic accuracy, treatment planning and patient care. Therefore, it is of interest to assess the knowledge, awareness and attitudes of pediatric dental professionals in India toward AI integration. While the majority recognized the benefits of AI, significant knowledge gaps and barriers such as cost, ethical concerns and lack of training were identified. A statistically significant association was found between awareness levels and years of experience as well as practice settings. These findings underscore the need for structured educational programs to support AI adoption in pediatric dentistry.</p>","PeriodicalId":8962,"journal":{"name":"Bioinformation","volume":"21 6","pages":"1647-1650"},"PeriodicalIF":1.9,"publicationDate":"2025-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12449532/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145111957","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Retrospective study on MRI accuracy in assessing liver fibrosis among patients with chronic liver disease. MRI评估慢性肝病患者肝纤维化准确性的回顾性研究。
IF 1.9
Bioinformation Pub Date : 2025-06-30 eCollection Date: 2025-01-01 DOI: 10.6026/973206300211643
Subha Santhoshi Vanka, Nikita Rao Nalla, Shaheed Shaik, Navneeth Jayaprakash, Mohammed Zakiullah Shareef, Sneha Mahalpure
{"title":"Retrospective study on MRI accuracy in assessing liver fibrosis among patients with chronic liver disease.","authors":"Subha Santhoshi Vanka, Nikita Rao Nalla, Shaheed Shaik, Navneeth Jayaprakash, Mohammed Zakiullah Shareef, Sneha Mahalpure","doi":"10.6026/973206300211643","DOIUrl":"10.6026/973206300211643","url":null,"abstract":"<p><p>Magnetic resonance imaging (MRI) is increasingly being utilized for the non-invasive liver fibrosis evaluation among chronic liver disease (CLD) patients. Therefore, it is of interest to assess the staging and diagnostic accuracy of MRI for liver fibrosis compared to histopathological outcome in 150 patients with CLD. MRI data were analyzed with advanced techniques such as elastography and T1/T2 mapping and these results were matched against fibrosis stages ascertained through biopsy. The sensitivity and specificity of MRI in detecting extensive fibrosis ≥F2 were 88% and 91%, respectively. Fibrosis scores determined by MRI were correlated with histopathological stage with r = 0.87, p < 0.01. The findings revealed MRI as an effective non-invasive modality for liver fibrosis that, complementarily, decreases the position of invasive biopsy in patients with CLD.</p>","PeriodicalId":8962,"journal":{"name":"Bioinformation","volume":"21 6","pages":"1643-1646"},"PeriodicalIF":1.9,"publicationDate":"2025-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12449564/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145111961","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Susceptibility and severity of Covid-19 in different blood groups. 不同血型对Covid-19的易感性和严重程度。
IF 1.9
Bioinformation Pub Date : 2025-06-30 eCollection Date: 2025-01-01 DOI: 10.6026/973206300211581
Ritesh Upadhyay, Ravikant Mahale, Pawan Nandurkar, Sonali Tripathi
{"title":"Susceptibility and severity of Covid-19 in different blood groups.","authors":"Ritesh Upadhyay, Ravikant Mahale, Pawan Nandurkar, Sonali Tripathi","doi":"10.6026/973206300211581","DOIUrl":"10.6026/973206300211581","url":null,"abstract":"<p><p>The relation of ABO and Rh blood groups with susceptibility and severity of COVID-19 among 120 patients is it of interest. Blood group A showed the highest infection rate of 37.5%, while the lowest was that of blood group O, at 20%. Susceptibility was a little higher in Rh-positive patients and the highest prevalence of severe disease was found among patients with blood group AB, at 30%. Results show that groups A and AB are associated with increased susceptibility and severity, which may help identify at-risk populations to target public health interventions. Further studies can help refine such associations and inform preventive strategies.</p>","PeriodicalId":8962,"journal":{"name":"Bioinformation","volume":"21 6","pages":"1581-1584"},"PeriodicalIF":1.9,"publicationDate":"2025-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12449514/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145112024","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A review on mTOR inhibitor use and outcomes of COVID-19 among patients with kidney transplantation. 肾移植患者使用mTOR抑制剂及COVID-19预后的研究进展
IF 1.9
Bioinformation Pub Date : 2025-06-30 eCollection Date: 2025-01-01 DOI: 10.6026/973206300211447
Sawai Singh Rathore, Vanessa Vidaurre Corrales, Ashwin Hassan Gopala, Hamam Aneis, Ibrahim Marouf Yasin Al Shyyab, Mutaz AlBeetar, Samah Mohamed Kannas, Omar Jihad Saleh Almistarihi, Mohamed Hamed Daoud
{"title":"A review on mTOR inhibitor use and outcomes of COVID-19 among patients with kidney transplantation.","authors":"Sawai Singh Rathore, Vanessa Vidaurre Corrales, Ashwin Hassan Gopala, Hamam Aneis, Ibrahim Marouf Yasin Al Shyyab, Mutaz AlBeetar, Samah Mohamed Kannas, Omar Jihad Saleh Almistarihi, Mohamed Hamed Daoud","doi":"10.6026/973206300211447","DOIUrl":"10.6026/973206300211447","url":null,"abstract":"<p><p>Kidney transplant recipients are at increased risk of severe COVID-19 due to immunosuppression and the impact of mTOR inhibitors on outcomes remains unclear. Hence, we evaluated 24 observational studies with 5,882 kidney transplant patients to assess the association of mTOR inhibitors with COVID-19 severity and mortality. Random-effects models showed that mTOR inhibitors were significantly associated with reduced mortality (OR=0.63, 95% CI 0.48-0.83, P=0.001) but not with COVID-19 severity (OR=0.70, 95% CI 0.41-1.20, P=0.865). Thus, mTOR inhibitors may provide a survival benefit in kidney transplant patients with COVID-19, highlighting the need for further research.</p>","PeriodicalId":8962,"journal":{"name":"Bioinformation","volume":"21 6","pages":"1447-1453"},"PeriodicalIF":1.9,"publicationDate":"2025-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12449486/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145111812","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Impact of surgical margins on local recurrence rates in breast-conserving surgery. 保乳手术切缘对局部复发率的影响。
IF 1.9
Bioinformation Pub Date : 2025-06-30 eCollection Date: 2025-01-01 DOI: 10.6026/973206300211631
Rakshana Munusamy, Mohammed Mohsen Abdel Raouf, Shakthiyan Gopal, J Naveen Bose, Manisha Mohammed Shaan, Kaushik J
{"title":"Impact of surgical margins on local recurrence rates in breast-conserving surgery.","authors":"Rakshana Munusamy, Mohammed Mohsen Abdel Raouf, Shakthiyan Gopal, J Naveen Bose, Manisha Mohammed Shaan, Kaushik J","doi":"10.6026/973206300211631","DOIUrl":"10.6026/973206300211631","url":null,"abstract":"<p><p>A conservative surgical breast intervention is broadly acceptable as an appropriate treatment option in preliminary stages of breast cancer and is recommended in order to establish oncologic safety while achieving aesthetics of the breast. Therefore, it is of interest to follow-up for five years among 150 patients who received breast-conserving surgery with an understanding of surgical margin status which might be reported positive, close, or negative; the mean incidence of overall local recurrence is estimated at 8%. Higher values, however, were recorded in positive margin patients of 25%. Close and negative margins were significantly at 10% and 5%, respectively. Tumour size and grade, with the margin, are significant indicators of recurrence of p <0.05. In such findings lies the critical relevance of achieving the surgical margins clean in order to minimize the percentage of local recurrences and have better long term results in a patient with carcinoma breast.</p>","PeriodicalId":8962,"journal":{"name":"Bioinformation","volume":"21 6","pages":"1631-1634"},"PeriodicalIF":1.9,"publicationDate":"2025-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12449512/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145111828","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Linking oral health with other health domains among edentulous patients. 将无牙患者的口腔健康与其他健康领域联系起来。
IF 1.9
Bioinformation Pub Date : 2025-06-30 eCollection Date: 2025-01-01 DOI: 10.6026/973206300211391
Mayur Mishra, Mandeepsinh Gohil, Gautam Rai, Jemin Borda, Sahil Khokhar, Rohan Shambhuwani
{"title":"Linking oral health with other health domains among edentulous patients.","authors":"Mayur Mishra, Mandeepsinh Gohil, Gautam Rai, Jemin Borda, Sahil Khokhar, Rohan Shambhuwani","doi":"10.6026/973206300211391","DOIUrl":"10.6026/973206300211391","url":null,"abstract":"<p><p>Nutritional, emotional dimensions and oral health related quality of life among edentulous patient using Oral health impact profile-edentulous (OHIP-EDENT), Mini nutritional Assessment (Nestle 2009) and Beck's Depression Inventory (BDI) is of interest. The response showed there are 44.8% of participants at risk of malnutrition. And 23.6% diagnosed with malnutrition. Beck's depression inventory found out that around 23.6% to 12.4% had symptoms of mild to moderate depression. Gender wise Comparison of Variables done to find out association between them, it showed only OHIEDENT score were found to be significant. Based on the findings of this study, it was concluded that the self-reported quality of life can be influenced by the tooth loss.</p>","PeriodicalId":8962,"journal":{"name":"Bioinformation","volume":"21 6","pages":"1391-1396"},"PeriodicalIF":1.9,"publicationDate":"2025-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12449548/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145111856","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effect of Reiki therapy on quality of life among adolescents. 灵气疗法对青少年生活质量的影响。
IF 1.9
Bioinformation Pub Date : 2025-06-30 eCollection Date: 2025-01-01 DOI: 10.6026/973206300211375
Gurav Priyankaben Rajeshbhai, Mahalakshmi B, Siva Subramanian N
{"title":"Effect of Reiki therapy on quality of life among adolescents.","authors":"Gurav Priyankaben Rajeshbhai, Mahalakshmi B, Siva Subramanian N","doi":"10.6026/973206300211375","DOIUrl":"10.6026/973206300211375","url":null,"abstract":"<p><p>Adolescents with cancer face numerous challenges that impair their quality of life (QoL), including physical discomfort, emotional stress and disruptions to normal development. Therefore, it is of interest to study the impact of Reiki therapy on QoL among adolescents aged 13-17 years with cancer in Gujarat, India. A quasi-experimental pre-test and post-test control group design was employed with 92 participants, equally divided into experimental and control groups. Quality of life was assessed using the WHOQOL-100 tool. Post-intervention results demonstrated a significant improvement in the experimental group's QoL (Mean difference = 13.9, p < 0.001), while the control group showed minimal change. Thus, the potential of Reiki therapy as an effective intervention to enhance the QoL of adolescents undergoing cancer treatment is highlighted.</p>","PeriodicalId":8962,"journal":{"name":"Bioinformation","volume":"21 6","pages":"1375-1379"},"PeriodicalIF":1.9,"publicationDate":"2025-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12449561/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145111875","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Molecular docking analysis of N-myristoyl-transferase with small molecules from the ZINC database for screening potential anti-malarial drugs. n -肉豆浆酰基转移酶与锌数据库小分子的分子对接分析用于筛选潜在的抗疟疾药物。
IF 1.9
Bioinformation Pub Date : 2025-06-30 eCollection Date: 2025-01-01 DOI: 10.6026/973206300211397
Anbuselvam Mohan, Katherine C Ji, Balasubramanian Chitra, Anbuselvam Jeeva, Hai-Feng Ji
{"title":"Molecular docking analysis of N-myristoyl-transferase with small molecules from the ZINC database for screening potential anti-malarial drugs.","authors":"Anbuselvam Mohan, Katherine C Ji, Balasubramanian Chitra, Anbuselvam Jeeva, Hai-Feng Ji","doi":"10.6026/973206300211397","DOIUrl":"10.6026/973206300211397","url":null,"abstract":"<p><p>Malaria is one of the major global public health problems, is primarily caused by protozoan parasites of the genus <i>Plasmodium</i> and transmitted through the bites of infected female <i>Anopheles</i> mosquitoes. N-Myristoyltransferase (NMT) is an important drug target, particularly for <i>Plasmodium vivax</i>. Therefore, it is of interest to describe the molecular docking analysis of N-myristoyl-transferase with small molecules from the ZINC database for screening potential anti-malarial drugs. Hence, we report four potential compounds namely ZINC37555319, ZINC41016284, ZINC41016205, and ZINC47160805 with acceptable ADME properties for further consideration.</p>","PeriodicalId":8962,"journal":{"name":"Bioinformation","volume":"21 6","pages":"1397-1403"},"PeriodicalIF":1.9,"publicationDate":"2025-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12449506/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145111931","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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