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Epidemiology, molecular prevalence and prevention on canine parvovirus in India: A review. 印度犬细小病毒的流行病学、分子流行率和预防:综述。
IF 1.9
Bioinformation Pub Date : 2024-05-31 eCollection Date: 2024-01-01 DOI: 10.6026/973206300200536
Vanjavaka Pavana Jyothi, Mohana Subramanian Bhaskaran, Vijay A K B Gundi
{"title":"Epidemiology, molecular prevalence and prevention on canine parvovirus in India: A review.","authors":"Vanjavaka Pavana Jyothi, Mohana Subramanian Bhaskaran, Vijay A K B Gundi","doi":"10.6026/973206300200536","DOIUrl":"10.6026/973206300200536","url":null,"abstract":"<p><p>Canine parvovirus (CPV) is a highly contagious and lethal virus that causes severe gastroenteritis and myocarditis in young dogs. In 1978, CPV has rapidly spread worldwide, resulting in outbreaks and high morbidity rates among dog populations. Over a decade, CPV has undergone genetic changes, leading to the emergence of different genotypes (CPV-2a, CPV-2b, and CPV-2c), which have expanded its host range to include cats and tissue culture cells. This review focuses on CPV-2 outbreaks in India from 2010 to 2023, analyzing gene lengths covering 274-438 amino acids in the VP2 gene which are collected from the NCBI database to investigate CPV epidemiology and diversity. The study highlighted substantial differences in seroprevalence over the period for CPV-2 (7%), CPV-2a (45%), CPV-2b (12%), and CPV-2c (36%). Our study found significant seroprevalence differences among CPV variants, with CPV-2a being the most prevalent, underscoring the need for effective diagnostic and preventive strategies.</p>","PeriodicalId":8962,"journal":{"name":"Bioinformation","volume":"20 5","pages":"536-546"},"PeriodicalIF":1.9,"publicationDate":"2024-05-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11309098/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141916034","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Insights from assessment for arrhythmia after CoViD-19 vaccination among Indians. 印度人接种 CoViD-19 疫苗后心律失常评估的启示。
IF 1.9
Bioinformation Pub Date : 2024-05-31 eCollection Date: 2024-01-01 DOI: 10.6026/973206300200430
S Sunita, Madhu Bala Negi, Moti Lal, Chandan Kumar, Manish Kumar
{"title":"Insights from assessment for arrhythmia after CoViD-19 vaccination among Indians.","authors":"S Sunita, Madhu Bala Negi, Moti Lal, Chandan Kumar, Manish Kumar","doi":"10.6026/973206300200430","DOIUrl":"10.6026/973206300200430","url":null,"abstract":"<p><p>Post-vaccination myocarditis is usually moderate and transient, recovering quickly with conservative treatment. Therefore, it is of interest to assess for arrhythmia after CoViD-19 vaccination among Indians. We looked for ECG abnormalities in a small cohort of 50 participants after 52 weeks after receiving the Oxford/AstraZeneca CoViD-19 vaccination. Data shows that post-vaccination myocarditis is typically mild and transient, with most cases resolving swiftly through conservative management. Thus, it is unlikely that this vaccine will induce severe arrhythmias or life-threatening cardiac events in the general population.</p>","PeriodicalId":8962,"journal":{"name":"Bioinformation","volume":"20 5","pages":"430-433"},"PeriodicalIF":1.9,"publicationDate":"2024-05-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11309109/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141916061","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Linking periodontal pathogens with endoperio lesions. 将牙周病原体与术中病变联系起来。
IF 1.9
Bioinformation Pub Date : 2024-05-31 eCollection Date: 2024-01-01 DOI: 10.6026/973206300200583
Sakshi Malik, K Sai Priyanka, Rinkee Mohanty, Anas Abdul Khader, Shekhar Prasad, Souradeep Dey, Jeethu John Jerry
{"title":"Linking periodontal pathogens with endoperio lesions.","authors":"Sakshi Malik, K Sai Priyanka, Rinkee Mohanty, Anas Abdul Khader, Shekhar Prasad, Souradeep Dey, Jeethu John Jerry","doi":"10.6026/973206300200583","DOIUrl":"10.6026/973206300200583","url":null,"abstract":"<p><p>Endodontic-periodontal diseases pose difficulties for the practitioner in diagnosing and predicting the success of the affected teeth. Therefore, it is of interest to correlate between periodontal infections and endodontic periodontal disorders. 50 patients of both sexes were included in this study. 28 of the 50 patients were men and 22 were women. Participants with a history of endodontic and periodontal lesions on the same tooth were chosen. A polymerase chain reaction experiment was carried out and relationships were formed. Data shows that isolates of <i>Porphyromonas gingivalis</i>, <i>Aggregatibacter actinomycetemcomitans</i> and <i>Tannerella forsythia</i> were identified in 91% of the periodontium, 12% of the endodontium, and 51% of the endodontium, respectively. Targeted bacterial species were associated with periodontal and endodontic disorders that occurred concurrently. Therefore, it is plausible to speculate that dentinal tubules serve as a channel for the dissemination of microorganisms.</p>","PeriodicalId":8962,"journal":{"name":"Bioinformation","volume":"20 5","pages":"583-586"},"PeriodicalIF":1.9,"publicationDate":"2024-05-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11309118/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141916063","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Management of oral aphthous ulcer: A review. 口腔阿弗他溃疡的治疗:综述。
IF 1.9
Bioinformation Pub Date : 2024-05-31 eCollection Date: 2024-01-01 DOI: 10.6026/973206300200434
Bhart Vashishat, Shruti Sinha, Tanmay Srivastava, Anuj Mishra, Kavleen Kaur Sethi, Sparsh Srivastava, Pratik Surana
{"title":"Management of oral aphthous ulcer: A review.","authors":"Bhart Vashishat, Shruti Sinha, Tanmay Srivastava, Anuj Mishra, Kavleen Kaur Sethi, Sparsh Srivastava, Pratik Surana","doi":"10.6026/973206300200434","DOIUrl":"10.6026/973206300200434","url":null,"abstract":"<p><p>Aphthous ulcers, also known as canker sores, are a common oral condition characterized by recurrent, painful, small ulcers that typically arise on the non-keratinized mucous membranes within the mouth. Although the pathogenesis of aphthous ulcers is not completely understood; it is believed to be involved in a combination of genetic predisposition, local trauma, stress, hormonal changes, and certain environmental factors. Thus, management of aphthous ulcer revolves around reducing pain, promoting healing and preventing recurrence.</p>","PeriodicalId":8962,"journal":{"name":"Bioinformation","volume":"20 5","pages":"434-438"},"PeriodicalIF":1.9,"publicationDate":"2024-05-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11309097/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141916064","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A review on guided bone regeneration using titanium mesh. 使用钛网引导骨再生综述。
IF 1.9
Bioinformation Pub Date : 2024-05-31 eCollection Date: 2024-01-01 DOI: 10.6026/973206300200562
Saad Obaid Alazmi
{"title":"A review on guided bone regeneration using titanium mesh.","authors":"Saad Obaid Alazmi","doi":"10.6026/973206300200562","DOIUrl":"10.6026/973206300200562","url":null,"abstract":"<p><p>The gold standard for bone regeneration in atrophic ridge patients is guided bone regeneration (GBR). This makes it possible to get enough bone volume for an appropriate implant-prosthetic rehabilitation. The barrier membranes must meet the primary GBR design requirements, which include adequate integration with the surrounding tissue, spaciousness and clinical manageability. Titanium mesh's superior mechanical qualities and biocompatibility have broadened the indications of GBR technology, enabling it to be used to restore alveolar ridges with more significant bone defects. GBR with titanium mesh is being used in many clinical settings and for a range of clinical procedures. Furthermore, several advancements in digitalization and material modification have resulted from the study of GBR using titanium mesh. Hence, we report a review on the various characteristics of titanium mesh and its current use in clinical settings for bone augmentation.</p>","PeriodicalId":8962,"journal":{"name":"Bioinformation","volume":"20 5","pages":"562-565"},"PeriodicalIF":1.9,"publicationDate":"2024-05-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11309112/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141916023","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Psychological and socio-cultural factors affecting latrine ownership and usage in rural South India. 南印度农村地区影响厕所所有权和使用率的心理和社会文化因素。
IF 1.9
Bioinformation Pub Date : 2024-05-31 eCollection Date: 2024-01-01 DOI: 10.6026/973206300200502
Sebastian Nancy, Kamal Batcha Mujibur Rahman, Selvaraju Sathish Kumar, Kasinathan Murugesan, Uthirapathy Udhayakumar
{"title":"Psychological and socio-cultural factors affecting latrine ownership and usage in rural South India.","authors":"Sebastian Nancy, Kamal Batcha Mujibur Rahman, Selvaraju Sathish Kumar, Kasinathan Murugesan, Uthirapathy Udhayakumar","doi":"10.6026/973206300200502","DOIUrl":"10.6026/973206300200502","url":null,"abstract":"<p><p>The levels of latrine utilization were lower than the levels of latrine ownership in rural areas owing to certain psycho-social barriers hindering latrine construction and consistent utilization. The study was aimed to identify the proportion of latrine construction and usage and to explore the psychological, socio-cultural and structural factors influencing latrine ownership and utilization. A community-based cross-sectional study was carried out at the four villages of Villupuram district for three months. After IEC clearance, information was collected from a representative sample of 422 households. Direct observation of the latrines was employed along with surveys. The data were entered and analysed in MS Excel. Categorical variables were expressed as frequencies and percentages. Further, the reasons were categorized into psychological, socio-cultural and structural factors. About 54.7% households owned a latrine and among them 46.8% were using it. Psycho-social factors such as convenience, habitual nature, privacy and space constraints in open defecation influenced latrine ownership. Fear of snakes and insects, safety and protection, time saving and proper functioning latrines with availability of water facilitated latrine utilization are of concern. A multi-faceted strategy employing context-specific behaviour change communication along with Government's financial support would improve both latrine construction and utilization.</p>","PeriodicalId":8962,"journal":{"name":"Bioinformation","volume":"20 5","pages":"502-507"},"PeriodicalIF":1.9,"publicationDate":"2024-05-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11309095/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141916069","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A report on the impact of CGF on hard and soft tissues around endo-perio lesion. 关于 CGF 对内痔周围软硬组织影响的报告。
IF 1.9
Bioinformation Pub Date : 2024-05-31 eCollection Date: 2024-01-01 DOI: 10.6026/973206300200483
Sai Krishna Bingi, K Sitamahalakshmi, M Jaya Nagendra Krishna, Shaik Imran, Govardhani Krishnakumar
{"title":"A report on the impact of CGF on hard and soft tissues around endo-perio lesion.","authors":"Sai Krishna Bingi, K Sitamahalakshmi, M Jaya Nagendra Krishna, Shaik Imran, Govardhani Krishnakumar","doi":"10.6026/973206300200483","DOIUrl":"10.6026/973206300200483","url":null,"abstract":"<p><p>There is an increased chance of further periodontal deterioration due to severe intrabony defect. There are s different patho physiologies for perio-endo lesions, ranging from quite basic to rather complicated but to make the right diagnosis, one must be aware of various illness processes also a careful history taking, examination, and the application of specialized tests can help achieve this. Each form of endodontic-periodontal illness has a different prognosis and course of therapy and all kinds of endo-perio lesions require endodontic and periodontal treatments are necessary for primary periodontal disease with subsequent endodontic involvement and real mixed endodontic-periodontal disorders. The severity of the periodontal disease and how well the patient responds to therapy will determine how these situations turn out. Because autologous platelet concentrates are enriched with growth factors, such as concentrated growth factor (CGF), they may enhance surgical outcomes. CGF is inserted into the appropriate intrabony defect following traditional flap debridement. Following flap surgery, the tooth in question had a root canal operation. Volumetric analysis was performed on both groups before to surgery and nine months after the procedure. It has been discovered that the defect area has a much larger bone volume due to the high levels of CGF, a regenerative and reconstructive growth factor that promotes early and high bone fill.</p>","PeriodicalId":8962,"journal":{"name":"Bioinformation","volume":"20 5","pages":"483-486"},"PeriodicalIF":1.9,"publicationDate":"2024-05-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11309119/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141916022","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Post-endodontic pain following root canal treatment in permanent teeth among Indian paediatric patients. 印度儿童恒牙根管治疗后的根管治疗后疼痛。
IF 1.9
Bioinformation Pub Date : 2024-05-31 eCollection Date: 2024-01-01 DOI: 10.6026/973206300200571
Sajid Khan, Arunendra Singh Chauhan, Khushtar Haider, Saima Ali, Parul Shakarwal, Akriti Chauhan
{"title":"Post-endodontic pain following root canal treatment in permanent teeth among Indian paediatric patients.","authors":"Sajid Khan, Arunendra Singh Chauhan, Khushtar Haider, Saima Ali, Parul Shakarwal, Akriti Chauhan","doi":"10.6026/973206300200571","DOIUrl":"10.6026/973206300200571","url":null,"abstract":"<p><p>Pulp status in permanent teeth and post endodontic pain (PEP) has not been assessed properly in pediatric patients. Therefore, it is of interest to assess the prevalence, severity of PEP in permanent teeth after root canal therapy and retreatment in paediatric patients. Hence, 127 pediatric patients who had root canal therapy (RCT) for permanent teeth with necrotic pulp, vital pulporendodonticre treatment were considered. Assessment of incidence intensity of PEP at 6 hours and 18 hours after therapy was completed. The incidence and intensity of PEP in permanent teeth in paediatric patients was greater in teeth with vital pulp. It was low in teeth with necrotic pulp. The incidence of spontaneous PEP was greater in all treatment groups as compared to stimulated PEP at 6 hours after treatment. Thus, root canal therapy of teeth with viable pulp produced a noticeably greater incidence and intensity of PEP in permanent teeth in paediatric patients.</p>","PeriodicalId":8962,"journal":{"name":"Bioinformation","volume":"20 5","pages":"571-574"},"PeriodicalIF":1.9,"publicationDate":"2024-05-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11309111/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141916067","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Predictors for diabetes and hypertension among bus drivers and conductors in South India. 南印度公交车司机和售票员患糖尿病和高血压的预测因素。
IF 1.9
Bioinformation Pub Date : 2024-05-31 eCollection Date: 2024-01-01 DOI: 10.6026/973206300200495
Kamal Batcha Mohamed Ali, Selvaraju Sathish Kumar, Perumal Kandasami Govindarajan, Kamal Batcha Mujibur Rahman, Sebastian Nancy
{"title":"Predictors for diabetes and hypertension among bus drivers and conductors in South India.","authors":"Kamal Batcha Mohamed Ali, Selvaraju Sathish Kumar, Perumal Kandasami Govindarajan, Kamal Batcha Mujibur Rahman, Sebastian Nancy","doi":"10.6026/973206300200495","DOIUrl":"10.6026/973206300200495","url":null,"abstract":"<p><p>Bus drivers and conductors are facing various health hazards due to stressful working conditions. They are exposed to various occupational hazards which lead to deterioration of their health over a period of time. Therefore, it is of interest to evaluate the prevalence of diabetes and hypertension among bus drivers and conductors and to determine the factors associated with diabetes and hypertension. This cross-sectional study was done among 293 bus drivers and 157 conductors during March 2018 to December 2018 and the data was collected using a semi structured questionnaire after obtaining informed consent. Each individual was investigated for Blood sugar and Blood Pressure. Out of 450 study participants, about 6.9% were diabetic and 50.2% were hypertensive. Transport workers with single marital status, those who belong to rural areas and drivers were significant predictors for diabetes. Overweight was significantly associated with the Diabetes in negative direction. Marital status, years of experience and anxiety were significantly associated with hypertension. Hemoglobin level, total cholesterol level and blood urea level also emerged as predictors for Hypertension. Non-communicable diseases like diabetes and hypertension have surpassed the communicable diseases in affecting the health of people with distinct occupations like bus drivers and conductors.</p>","PeriodicalId":8962,"journal":{"name":"Bioinformation","volume":"20 5","pages":"495-501"},"PeriodicalIF":1.9,"publicationDate":"2024-05-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11309115/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141916068","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Synthesis and molecular docking analysis of MBH adducts' derived amides as potential β-lactamase inhibitors. 作为潜在 β-内酰胺酶抑制剂的 MBH 加合物衍生酰胺的合成和分子对接分析。
IF 1.9
Bioinformation Pub Date : 2024-05-31 eCollection Date: 2024-01-01 DOI: 10.6026/973206300200449
Hamid Ullah, Sadia Majid, Asma Abro, Taj Ur Rahman, Abdul Majeed Khan, Mehboob Ahmed, Muhammad Asif, Asma Yousafzai, Riffat Ullh, Peter Natesan Pushparaj, Mahmood Rasool
{"title":"Synthesis and molecular docking analysis of MBH adducts' derived amides as potential <i>β-lactamase</i> inhibitors.","authors":"Hamid Ullah, Sadia Majid, Asma Abro, Taj Ur Rahman, Abdul Majeed Khan, Mehboob Ahmed, Muhammad Asif, Asma Yousafzai, Riffat Ullh, Peter Natesan Pushparaj, Mahmood Rasool","doi":"10.6026/973206300200449","DOIUrl":"10.6026/973206300200449","url":null,"abstract":"<p><p>Humans suffer from various diseases that require more specific drugs to target them. Among the different potent agents, <i>β-lactamase</i>s serve as good antibacterial agents; however, <i>β-lactamase</i>s are resistant to such antibiotics. The present study was designed to prepare efficient <i>β-lactamase</i> inhibitor amides (12-15) from inexpensive, easily accessible, and bioactive precursors; Morita Baylis Hillman (MBH) adducts (5-8). The adducts (5-8) were primarily prepared by treating their respective aldehydes with the corresponding acrylate in the presence of an organic Lewis base at ambient temperature. The compounds were characterized using mass spectrometry, FTIR and NMR spectroscopy. Furthermore, <i>in silico</i> studies (using AutoDock Tools and AutoDock Vina programs) on the adduct and corresponding amide product revealed that all MBH adducts (5-8) and their product amides (12-15) are significant inhibitors of <i>β-lactamase</i>. Additionally, among the MBH adducts, adduct 7 showed the highest binding affinity with <i>β-lactamase</i>, whereas amide 15 was identified as a highly potent antibacterial based on its docking score (-8.6). In addition, the absorption, distribution, metabolism, and excretion (ADME) test of the synthesized compounds demonstrated that all compounds showed drug-likeness properties.</p>","PeriodicalId":8962,"journal":{"name":"Bioinformation","volume":"20 5","pages":"449-459"},"PeriodicalIF":1.9,"publicationDate":"2024-05-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11309101/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141916072","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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