{"title":"A prospective clinical study to understand the factors affecting healing of intestinal primary repair and anastomosis at a tertiary care centre.","authors":"Akhilesh Ratnakar, Shikha Pandey, Luv Gupta, Aditi Kumari, Talha Saad, Sheela Jain, Deepak Shrivastava","doi":"10.6026/973206300223728","DOIUrl":"10.6026/973206300223728","url":null,"abstract":"<p><p>One of the greatest worrisome negative consequences via intestinal anastomosis is anastomotic leak (AL). Therefore, it is of interest to evaluate the risk components of intestinal resection and anastomosis. AL appears higher in older age group that is above 50 years and with higher BMI (generally obese type I). Conditions like diabetes, hypertension, benign and malignant lesions of intestine and type of procedure (routine and emergency) resulted in increased incidence of AL. Thus, data shows the clinical and surgical characteristics linked with anastomotic leak, which may improve pre-operative risk assessment, perioperative management and post-operative healing after intestinal repair and anastomosis.</p>","PeriodicalId":8962,"journal":{"name":"Bioinformation","volume":"22 6","pages":"3728-3731"},"PeriodicalIF":1.9,"publicationDate":"2026-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13545923/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148896567","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Hydrophilic versus hydrophobic implant coatings: A comparative osseointegration study.","authors":"Ravi Ranjan Sinha, Sandeep Kashyap, Gourav Kumar Sahu, Gurdeep Kaur Chauhan, Pragati Mishra, Mayadevi Mayadevi","doi":"10.6026/973206300223289","DOIUrl":"10.6026/973206300223289","url":null,"abstract":"<p><p>Achieving rapid and stable osseointegration remains a persistent challenge in dental implantology, particularly with variations in implant surface properties. Therefore, it is of interest to compare the effects of hydrophilic and hydrophobic implant surface coatings on osseointegration using clinical and radiographic parameters. Hence, a prospective comparative design involving 100 patients showed that hydrophilic implants yielded significantly higher implant stability (ISQ values) and reduced peri-implant bone loss over a 6-month follow-up period. Improved peri-implant soft tissue health, evidenced by reduced probing depth and bleeding on probing, was also observed in the hydrophilic group. Thus, we report hydrophilic surface modification as a superior strategy for enhancing early osseointegration and improving overall implant prognosis.</p>","PeriodicalId":8962,"journal":{"name":"Bioinformation","volume":"22 6","pages":"3289-3293"},"PeriodicalIF":1.9,"publicationDate":"2026-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13545868/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148896597","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
BioinformationPub Date : 2026-06-30eCollection Date: 2026-01-01DOI: 10.6026/973206300223226
Isha Akulwar-Tajane, Rajashree Naik
{"title":"Subjective dimensions of community participation following stroke: A qualitative approach.","authors":"Isha Akulwar-Tajane, Rajashree Naik","doi":"10.6026/973206300223226","DOIUrl":"10.6026/973206300223226","url":null,"abstract":"<p><p>Limited understanding of subjective dimensions of community participation remains a key gap in post-stroke rehabilitation. Therefore, it is of interest to explore lived experiences of 30 stroke survivors using cognitive interviews. Findings revealed reduced participation is mainly due to dependence, low self-efficacy and environmental barriers. Perceived social support and positive outcome expectations were identified as important facilitators of participation. Thus, we show the integration of subjective, patient-reported perspectives into rehabilitation assessment and intervention frameworks.</p>","PeriodicalId":8962,"journal":{"name":"Bioinformation","volume":"22 6","pages":"3226-3230"},"PeriodicalIF":1.9,"publicationDate":"2026-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13545860/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148896625","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A community-based screening programme to detect non-alcoholic fatty liver using FibroScan among healthy Indian adults.","authors":"Singhai Abhishek, Joshi Rajnish, Yadav Vikas, Ingle Vaibhav, Manoria Piyush","doi":"10.6026/973206300223332","DOIUrl":"10.6026/973206300223332","url":null,"abstract":"<p><p>Non-alcoholic fatty liver disease (NAFLD) remains substantially underdiagnosed in the general Indian population despite its rapidly increasing burden and close association with metabolic disorders. Therefore, it is of interest to evaluate the prevalence of NAFLD among Indian adults. Hence, 490 participants were included in the study. We identified NAFLD in 44.5% of population. NAFLD now poses a significant health challenge in India. Its strong association with obesity, diabetes, and dyslipidemia highlights the urgent need for targeted public health strategies and early intervention.</p>","PeriodicalId":8962,"journal":{"name":"Bioinformation","volume":"22 6","pages":"3332-3337"},"PeriodicalIF":1.9,"publicationDate":"2026-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13545965/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148896629","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Dissection of lymph node on longevity in breast and colorectal operation.","authors":"Deepak Premnarayan Gupta, Ritesh Yadav, Priyanshu Jain, Talha Saad, Akash Wamanrao Karale, Satyendra Mishra, Roopa Agrawal","doi":"10.6026/973206300223636","DOIUrl":"10.6026/973206300223636","url":null,"abstract":"<p><p>The dissection of the lymph nodes is customarily accomplished but argumentation pursues for the extent requisition to acquire lessen complications after the operation and diminished cancer burden. Therefore, it is of interest to appraise how lymph node excision impacts challenges after the surgery and influences the survival in respondents' encountered operation for the management of breast and colorectal cancer. The identification of metastatic nodes was substantially heightened with sufficient removal in juxtapose to those with insufficient removal (52.4% vs. 29.7%; p < 0.01), emphasizing the purpose of sufficient node harvesting. Thus, data shows a judicious and selective method of lymph node removal that guarantees precise cancer staging and survival advantages while reducing superfluous surgical morbidity.</p>","PeriodicalId":8962,"journal":{"name":"Bioinformation","volume":"22 6","pages":"3636-3639"},"PeriodicalIF":1.9,"publicationDate":"2026-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13545872/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148896479","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Comparative evaluation of salivary oxidative stress markers in oral leukoplakia and oral submucous fibrosis: A cross-sectional study.","authors":"Ashni Chatterjee, Sowjanya Gunukula, Mousami Kundu, Priya Sinha, Sameer Gupta, Gaurav Sharma","doi":"10.6026/973206300223294","DOIUrl":"10.6026/973206300223294","url":null,"abstract":"<p><p>Oral leukoplakia and oral submucous fibrosis (OSMF) are potentially malignant disorders with a significant risk of progressing to oral cancer. Oxidative stress is a key factor in their development, causing cellular damage and disease progression. Therefore, it is of interest to evaluate and compare salivary oxidative stress markers in patients with these conditions. Data shows high levels of oxidative stress and lower antioxidant levels in both conditions compared to healthy controls, with OSMF showing severe imbalance. Thus, we show salivary oxidative stress markers as potential non-invasive diagnostic tools for early detection and monitoring of oral potentially malignant disorders.</p>","PeriodicalId":8962,"journal":{"name":"Bioinformation","volume":"22 6","pages":"3294-3299"},"PeriodicalIF":1.9,"publicationDate":"2026-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13545963/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148896368","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
BioinformationPub Date : 2026-06-30eCollection Date: 2026-01-01DOI: 10.6026/973206300223449
Sushil Chand Verma, Ajita Tiwari, Irfan Ahmad Siddiqui
{"title":"Role of pre-operative anxiety on intraoperative anesthetic requirement and post-operative recovery: An observational study.","authors":"Sushil Chand Verma, Ajita Tiwari, Irfan Ahmad Siddiqui","doi":"10.6026/973206300223449","DOIUrl":"10.6026/973206300223449","url":null,"abstract":"<p><p>Pre-operative anxiety is commonly observed in patients undergoing surgical procedures and may influence perioperative outcomes. Therefore, it is of interest to evaluate the effect of pre-operative anxiety on intraoperative anesthetic requirements and post-operative recovery outcomes. A prospective observational study was conducted on 100 patients undergoing elective surgeries under general anesthesia, where pre-operative anxiety was assessed using the APAIS scale and correlated with anesthetic consumption and recovery parameters. Patients with higher anxiety levels required significantly greater doses of anesthetic agents, had higher post-operative pain scores and showed delayed recovery with increased analgesic requirements. Thus, data shows that pre-operative anxiety has a measurable impact on anesthetic management and recovery, highlighting the importance of early identification and appropriate management of pre-operative anxiety.</p>","PeriodicalId":8962,"journal":{"name":"Bioinformation","volume":"22 6","pages":"3449-3452"},"PeriodicalIF":1.9,"publicationDate":"2026-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13545901/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148896528","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
BioinformationPub Date : 2026-06-30eCollection Date: 2026-01-01DOI: 10.6026/973206300223551
Kumar Abhinav, Abhishek Chaudhary, Rajiv Rajan
{"title":"Effect of cisternostomy in managing cerebral swelling: A clinical study.","authors":"Kumar Abhinav, Abhishek Chaudhary, Rajiv Rajan","doi":"10.6026/973206300223551","DOIUrl":"10.6026/973206300223551","url":null,"abstract":"<p><p>Traumatic brain injury (TBI) often leads to cerebral edema, resulting in elevated intracranial pressure (ICP) and poor neurological outcomes. Therefore, it is of interest to evaluate the efficacy of cisternostomy in managing cerebral edema, showing a significant reduction in ICP and improved neurological outcomes, including Glasgow Coma Scale (GCS) and Glasgow Outcome Scale (GOS) scores. The procedure offers a less invasive alternative to decompressive craniectomy with fewer complications and favorable recovery. Data from 200 patients suggest its potential for improving long-term functional recovery. Thus, we report cisternostomy role as a viable intervention for ICP reduction and functional recovery in TBI patients.</p>","PeriodicalId":8962,"journal":{"name":"Bioinformation","volume":"22 6","pages":"3551-3555"},"PeriodicalIF":1.9,"publicationDate":"2026-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13545952/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148896541","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
BioinformationPub Date : 2026-06-30eCollection Date: 2026-01-01DOI: 10.6026/973206300223480
Karamvir Karamvir, Nitin Bhola
{"title":"Pectoralis major myocutaneous versus pectoralis major myofascial flap for type III and type IV tongue defects reconstruction in patients operated for squamous cell carcinoma: A protocol.","authors":"Karamvir Karamvir, Nitin Bhola","doi":"10.6026/973206300223480","DOIUrl":"10.6026/973206300223480","url":null,"abstract":"<p><p>Reconstruction following extensive resection of tongue squamous cell carcinoma remains challenging because the optimal pedicled flap for achieving superior functional recovery and aesthetic outcomes is still uncertain. Therefore, it is of interest to compare pectoralis major myocutaneous (PMMC) and pectoralis major myofascial (PMMF) flaps for reconstruction of Type III and Type IV tongue defects in patients undergoing surgical treatment for squamous cell carcinoma. Twenty-four eligible patients will be randomly allocated into two groups, and post-operative outcomes including flap-related complications, tongue shape, swallowing, speech and tongue mobility will be evaluated at 1 week, 1 month and 3 months using standardized clinical assessment scales. Functional and aesthetic outcomes between the two reconstruction techniques will be analyzed using appropriate statistical methods to determine differences in clinical performance and patient rehabilitation. Thus, data shows to generate evidence that supports selection of the most effective pedicled flap for tongue reconstruction and improves functional recovery, quality of life and clinical decision-making in resource-constrained settings.</p>","PeriodicalId":8962,"journal":{"name":"Bioinformation","volume":"22 6","pages":"3480-3485"},"PeriodicalIF":1.9,"publicationDate":"2026-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13545903/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148896424","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"0.1% octenidine versus 0.2% chlorhexidine mouthwashes for plaque-induced gingivitis: A triple-blinded randomized controlled trial.","authors":"Sharvari Pokale, Sneh Agrawal, Prajakta Rao, Pranita Dalave, Vivek Sharma, Sanpreet Singh Sachdev","doi":"10.6026/973206300223405","DOIUrl":"10.6026/973206300223405","url":null,"abstract":"<p><p>Plaque-induced gingivitis is commonly managed by mechanical plaque control, but adjunctive mouthrinses may improve outcomes. Therefore, it is of interest to compare 0.1% octenidine, 0.2% chlorhexidine and placebo in 66 patients with plaque-induced gingivitis treated with scaling and root planing. Gingival index, plaque index, stain index and colony-forming units were recorded at baseline, 7 days and 15 days. Both octenidine and chlorhexidine produced significant reductions in gingival inflammation, plaque and microbial load compared with placebo, while chlorhexidine caused significantly greater staining. Thus, 0.1% octenidine showed efficacy comparable to 0.2% chlorhexidine with better cosmetic acceptability, supporting its use as an alternative adjunct in plaque-induced gingivitis.</p>","PeriodicalId":8962,"journal":{"name":"Bioinformation","volume":"22 6","pages":"3405-3411"},"PeriodicalIF":1.9,"publicationDate":"2026-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13545944/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148896618","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}