BioinformationPub Date : 2025-06-30eCollection Date: 2025-01-01DOI: 10.6026/973206300211567
Dona Soman, Ramnath Elangovan, Dinesh C Maganti, Kamikazi Rachel, Muhoza Cedric, Igirubuntu John Peter
{"title":"Prevalence of maxillary midline diastema and its societal perception in patients at Remera health center, Rwanda.","authors":"Dona Soman, Ramnath Elangovan, Dinesh C Maganti, Kamikazi Rachel, Muhoza Cedric, Igirubuntu John Peter","doi":"10.6026/973206300211567","DOIUrl":"10.6026/973206300211567","url":null,"abstract":"<p><p>The prevalence of maxillary midline diastema and its societal perception among patients attending Remera health center, Rwanda is of interest. This descriptive cross-sectional quantitative study was done among patients attending Remera health center. The data collected on the prevalence of midline diastema and its societal perception was measured through SPSS software version 20 by applying descriptive analysis. To analyze the relationship between the variables, inferential statistics were adopted to analyze the relationship between variables. The study investigated the prevalence and perception of maxillary midline diastema, where 27.3% have maxillary midline diastema and 77.3% of all the patients attending Remera health center perceived maxillary midline diastema as a sign of beauty.</p>","PeriodicalId":8962,"journal":{"name":"Bioinformation","volume":"21 6","pages":"1567-1573"},"PeriodicalIF":1.9,"publicationDate":"2025-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12449533/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145112026","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Impact on Hydrotherapy: Contribution by Sake Dean Mahomed.","authors":"Mandala Sathwik, Satya Lakshmi Komarraju, Sathyanath D, Shrikanth Muralidharan","doi":"10.6026/973206300211574","DOIUrl":"10.6026/973206300211574","url":null,"abstract":"<p><p>Naturopathy, a healing science using the natural elements of earth, fire, water and air to treat the disorders, emphasizes the use of water in its solid, liquid and vapor form for the three-fold purpose. Steam or vapor baths, also part of some Indian traditions of Ayurveda and Unani, were introduced into England by Sake Dean Mahomed. Mahomed innovatively adopted Indian Medicated Vapour Baths and shampooing techniques adapting them for European practices, gaining recognition and getting various referrals from hospitals. Thus, his role in bringing Indian cultural and therapeutic practices to the West is significant.</p>","PeriodicalId":8962,"journal":{"name":"Bioinformation","volume":"21 6","pages":"1574-1576"},"PeriodicalIF":1.9,"publicationDate":"2025-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12449490/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145111752","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"<i>in vitro</i> evaluation of force required to luxate a newly loaded dental implant in bone.","authors":"Paulami Bagchi, Savita Hadakar, Ruchi Agrawal, Snehamoy Pradhan, Vikas Gupta, Arjun Kumar Sharma, Miral Mehta","doi":"10.6026/973206300211522","DOIUrl":"10.6026/973206300211522","url":null,"abstract":"<p><p>The mechanical force required to luxate newly loaded dental implants using synthetic bone blocks simulating D2 density is of interest. The average luxation force was 184.7 ± 12.3 N. Implants inserted with higher torque showed slightly greater resistance, though not statistically significant (p > 0.05). Results suggest moderate resistance to early implant removal. These findings may aid clinicians in planning safe implant retrieval procedures.</p>","PeriodicalId":8962,"journal":{"name":"Bioinformation","volume":"21 6","pages":"1522-1525"},"PeriodicalIF":1.9,"publicationDate":"2025-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12449541/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145111754","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"3D printing in orthodontics - Past, present and future: A systematic review and meta-analysis.","authors":"Sonia Dubey, Bhagabati Prasad Dash, Biswaroop Mohanty, Sanghamitra Jena, Nivedita Sahoo, Swati Singh","doi":"10.6026/973206300211766","DOIUrl":"10.6026/973206300211766","url":null,"abstract":"<p><p>The accuracy of orthodontic appliances made with 3D printing, such as aligners, bonding trays and surgical splints, compared to traditional methods is of interest. Fifteen studies were analyzed, focusing on fit, dimensional deviations and accuracy. Results showed 3D-printed aligners offer better accuracy and resistance than conventional ones. The fit of 3D-printed indirect bonding trays and retainers was clinically acceptable, with gypsum casts showing less volumetric change. 3D-printed NAM aligners improved accuracy, comfort and nasal symmetry. Thus, 3D printing offers better precision, accessibility and patient care in orthodontics.</p>","PeriodicalId":8962,"journal":{"name":"Bioinformation","volume":"21 6","pages":"1766-1774"},"PeriodicalIF":1.9,"publicationDate":"2025-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12449498/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145111774","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A KAP-based evaluation on the role of climate change in shaping dental practices.","authors":"Himanshu Balkumar Gupta, Sibani Sarangi, Rakesh Mutha, Suthar M B, Akash Ponnukumar, Vikram Karande, Ritik Kashwani","doi":"10.6026/973206300211416","DOIUrl":"10.6026/973206300211416","url":null,"abstract":"<p><p>Climate change poses a significant threat to oral health and the sustainability of dental care systems. Therefore, it is of interest to assess the dental students' knowledge, attitudes and practices (KAP) on climate change and sustainability. While most understood the environmental impact and felt responsible, fewer individuals adopted sustainable practices, such as maintaining digital records and segregating waste. Barriers included a lack of training and institutional support. The findings underscore the need for curriculum reforms and policy adjustments to foster sustainability in dentistry.</p>","PeriodicalId":8962,"journal":{"name":"Bioinformation","volume":"21 6","pages":"1416-1420"},"PeriodicalIF":1.9,"publicationDate":"2025-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12449487/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145111785","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"<i>In vitro</i> assessment of cytokine release from gingival fibroblasts exposed to periodontal pathogens.","authors":"Kaushal Pati Tripathi, Rohit Mishra, Varsha Choubey, Ajay Kumar, Arohi Aglawe, Anshul Gulati","doi":"10.6026/973206300211501","DOIUrl":"10.6026/973206300211501","url":null,"abstract":"<p><p>Cytokine responses of gingival fibroblasts from healthy and inflamed tissues upon exposure to <i>P. gingivalis</i> <i>lipopolysaccharide</i> (LPS) are of interest. Samples were obtained from 20 individuals undergoing periodontal procedures. Inflamed fibroblasts showed elevated secretion of IL-6, MCP-1, IL-8, and GRO. <i>P. gingivalis</i> LPS induced a stronger cytokine response than controls. Thus, inflamed fibroblasts can mount a secondary inflammatory response to periodontal pathogens.</p>","PeriodicalId":8962,"journal":{"name":"Bioinformation","volume":"21 6","pages":"1501-1505"},"PeriodicalIF":1.9,"publicationDate":"2025-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12449547/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145111804","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
BioinformationPub Date : 2025-06-30eCollection Date: 2025-01-01DOI: 10.6026/973206300211458
Rohit Divya Gunvanthbhai, Siva Subramanian N, Mahalakshmi B
{"title":"Effect of yoga and music on depression among antenatal Indian women.","authors":"Rohit Divya Gunvanthbhai, Siva Subramanian N, Mahalakshmi B","doi":"10.6026/973206300211458","DOIUrl":"10.6026/973206300211458","url":null,"abstract":"<p><p>Antenatal depression is a growing concern affecting maternal and fetal health, often left untreated due to stigma and limited resources. Therefore, it is of interest to evaluate the effectiveness of yoga and music therapy in reducing depression among pregnant women in urban Gujarat. Hence, a total of 180 antenatal women were assigned to either a yoga group (2-week intervention) or a music group (1-week intervention). Depression levels were assessed pre- and post-intervention using the Edinburgh Postnatal Depression Scale. The yoga group showed a significant reduction in depression scores (p < 0.001), while the music group showed a slight but non-significant improvement (p = 0.369). Results show that yoga is more effective than music in alleviating depressive symptoms during pregnancy.</p>","PeriodicalId":8962,"journal":{"name":"Bioinformation","volume":"21 6","pages":"1458-1462"},"PeriodicalIF":1.9,"publicationDate":"2025-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12449551/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145111880","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Effect of heavy metal exposure on human kidney cells.","authors":"Sahil Purushottambhai Patel, Charu Mishra, Versha Kumari, Sanket Patel, Kirti Nishant Vyas, Shruti Dalpatbhai Kalola","doi":"10.6026/973206300211539","DOIUrl":"10.6026/973206300211539","url":null,"abstract":"<p><p>Heavy metal cytotoxicity using lab-based cell culture of human kidney (HK-2) cells is of interest. The exposed cells contained lead (Pb), cadmium (Cd) and mercury (Hg) at dosages of 5 µM, 10 µM and 20 µM during incubation periods of 24 hours, 48 hours and 72 hours. Cadmium induced the maximum cell death through its dose-dependent pattern while exposing cells to 20 µM cadmium for 72 hours at 52.4%. Next in line was mercury which reduced cell viability to 60.8% and lead reduced it to 68.9% when cells were exposed to 20 µM for 72 hours. Under cadmium treatment at 20 µM the levels of ROS rose 2.3 times in the target cells. The cells experienced shrinkage of their size and developed membrane blisters through morphological transformations. This study reveals severe kidney damage because cadmium caused the worst impact on renal cell structure.</p>","PeriodicalId":8962,"journal":{"name":"Bioinformation","volume":"21 6","pages":"1539-1542"},"PeriodicalIF":1.9,"publicationDate":"2025-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12449519/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145111897","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Illuminating outcomes: Diode laser management of an uncommon leukoplakia of tongue - A case report.","authors":"Ramnath Elangovan, Keerthika Varadhan, Kowsalya Nallathambi, Dinesh C Maganti, Danilo Milanes Zambrano, Anitha Maganti","doi":"10.6026/973206300211490","DOIUrl":"10.6026/973206300211490","url":null,"abstract":"<p><p>Oral leukoplakia exists as a potentially cancerous tissue condition which frequently develops because of tobacco habit and various associated risks. The treatment approach with diode laser on leukoplakia was completed in a 61-year-old male who had a lateral tongue abnormality. A 940 nm diode laser applied in gated pulse mode performed the lesion removal which created minimal intraoperative bleeding and fast postoperative recovery with no sign of disease recurrence. The examination of tissue under a microscope showed hyperplastic stratified squamous epithelium together with dysplasia. Diode laser provides a powerful therapeutic option with minimal invasiveness for treating oral leukoplakia when used on medically vulnerable patients.</p>","PeriodicalId":8962,"journal":{"name":"Bioinformation","volume":"21 6","pages":"1490-1492"},"PeriodicalIF":1.9,"publicationDate":"2025-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12449481/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145111922","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
BioinformationPub Date : 2025-06-30eCollection Date: 2025-01-01DOI: 10.6026/973206300211357
Ramesh Dnyandeo Kurle, Veluri Ganesh, Dileep Khubya, Gadigeppa H Chittaragi
{"title":"Linking high-sensitivity C-reactive protein and dyslipidemia among patients with type 2 diabetes mellitus.","authors":"Ramesh Dnyandeo Kurle, Veluri Ganesh, Dileep Khubya, Gadigeppa H Chittaragi","doi":"10.6026/973206300211357","DOIUrl":"10.6026/973206300211357","url":null,"abstract":"<p><p>Type 2 diabetes is evaluated in a condition elevated hs-CRP is linked to an increased risk of myocardial infraction development. Therefore, it is of interest to evaluate the hs-CRP in patients with type 2 diabetes mellitus who were not diagnosed with hypertension. We included total 120 T2DM patients attended to general medicine department and 60 healthy controls also included in the case control study. We measured demographic, anthropometric and clinical parameters from all the subjects. The type 2 diabetes mellitus patients with hypertension who had increased hs-CRP levels had a greater incidence of myocardial infraction results death and morbidity when compared to type 2 diabetes mellitus patients without hypertension. We show that CRP is a strong predictor of hospital morbidity and mortality in patients with acute myocardial infarction who have diabetes with hypertension as well as those who do not have hypertension.</p>","PeriodicalId":8962,"journal":{"name":"Bioinformation","volume":"21 6","pages":"1357-1361"},"PeriodicalIF":1.9,"publicationDate":"2025-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12449554/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145111924","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}