{"title":"罗哌卡因加或不加鞘内芬太尼用于有蝎子咬伤史患者脊髓麻醉的效果：一项病例对照研究。","authors":"Sonali Tripathi, Vineet Mandrah, Ritesh Upadhyay, Ashwini Kumar Patel","doi":"10.6026/973206300211577","DOIUrl":null,"url":null,"abstract":"<p><p>Effect of ropivacaine with and without intrathecal fentanyl for spinal anesthesia among patients with scorpion bite is of interest. Patients in the fentanyl-ropivacaine combination group had faster onset of sensory blockade (5.2±1.1 versus 7.8±1.3 minutes, p<0.001) and significantly longer analgesia duration (290±15 versus 180±12 minutes, p<0.001) than patients in the ropivacaine-alone group. Hemodynamic stability and the incidence of adverse effects were similar between the two groups. These results indicate that intrathecal fentanyl enhances the efficacy of ropivacaine in this distinct patient population without compromising safety.</p>","PeriodicalId":8962,"journal":{"name":"Bioinformation","volume":"21 6","pages":"1577-1580"},"PeriodicalIF":1.9000,"publicationDate":"2025-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12449530/pdf/","citationCount":"0","resultStr":"{\"title\":\"Effect of ropivacaine with and without intrathecal fentanyl for spinal anesthesia among patients with scorpion bite history: A case control study.\",\"authors\":\"Sonali Tripathi, Vineet Mandrah, Ritesh Upadhyay, Ashwini Kumar Patel\",\"doi\":\"10.6026/973206300211577\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>Effect of ropivacaine with and without intrathecal fentanyl for spinal anesthesia among patients with scorpion bite is of interest. Patients in the fentanyl-ropivacaine combination group had faster onset of sensory blockade (5.2±1.1 versus 7.8±1.3 minutes, p<0.001) and significantly longer analgesia duration (290±15 versus 180±12 minutes, p<0.001) than patients in the ropivacaine-alone group. Hemodynamic stability and the incidence of adverse effects were similar between the two groups. These results indicate that intrathecal fentanyl enhances the efficacy of ropivacaine in this distinct patient population without compromising safety.</p>\",\"PeriodicalId\":8962,\"journal\":{\"name\":\"Bioinformation\",\"volume\":\"21 6\",\"pages\":\"1577-1580\"},\"PeriodicalIF\":1.9000,\"publicationDate\":\"2025-06-30\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12449530/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Bioinformation\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.6026/973206300211577\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2025/1/1 0:00:00\",\"PubModel\":\"eCollection\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Bioinformation","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.6026/973206300211577","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/1/1 0:00:00","PubModel":"eCollection","JCR":"","JCRName":"","Score":null,"Total":0}
Effect of ropivacaine with and without intrathecal fentanyl for spinal anesthesia among patients with scorpion bite history: A case control study.
Effect of ropivacaine with and without intrathecal fentanyl for spinal anesthesia among patients with scorpion bite is of interest. Patients in the fentanyl-ropivacaine combination group had faster onset of sensory blockade (5.2±1.1 versus 7.8±1.3 minutes, p<0.001) and significantly longer analgesia duration (290±15 versus 180±12 minutes, p<0.001) than patients in the ropivacaine-alone group. Hemodynamic stability and the incidence of adverse effects were similar between the two groups. These results indicate that intrathecal fentanyl enhances the efficacy of ropivacaine in this distinct patient population without compromising safety.
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