Linking serum malondialdehyde with dyslipidemia in patients with metabolic syndrome.

IF 1.9
Bioinformation Pub Date : 2025-06-30 eCollection Date: 2025-01-01 DOI:10.6026/973206300211693
Gadigeppa H Chittaragi, Dileep Khubya, Veluri Ganesh
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Abstract

Dyslipidemia and obesity is becoming an increasingly serious public health issue. Therefore, it is of interest to determine the serum levels of malondialdehyde (MDA) with dyslipidemia in patients with metabolic syndrome. The routine demographic, anthropometric and the biochemical parameters analyzed. Additionally, the degree of lipid peroxidation was measured by serum levels of malondialdehyde (MDA). The body mass index, systolic and diastolic blood pressure, fasting blood sugars, lipid profile significantly elevated in metabolic syndrome patients when compared to healthy controls. The serum MDA levels significantly elevated and correlated positively with abdominal hyperglycemia, hypertension, obesity and negatively with HDL (p=0.0001**). Thus, the early detection of people at risk for getting metabolic syndrome can be improved by measuring the MDA biomarker.

代谢综合征患者血清丙二醛与血脂异常的关系
血脂异常和肥胖正成为日益严重的公共卫生问题。因此,测定代谢综合征患者血脂异常患者血清丙二醛(MDA)水平具有重要意义。进行常规人口统计学、人体测量学及生化指标分析。此外,通过血清丙二醛(MDA)水平测定脂质过氧化程度。与健康对照组相比,代谢综合征患者的体重指数、收缩压和舒张压、空腹血糖、脂质谱显著升高。血清MDA水平显著升高,与腹部高血糖、高血压、肥胖呈正相关,与HDL呈负相关(p=0.0001**)。因此,可以通过测量MDA生物标志物来改善对代谢综合征高危人群的早期检测。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Bioinformation
Bioinformation MATHEMATICAL & COMPUTATIONAL BIOLOGY-
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