Jekee Patel, Parin Patel, Himarshi Upadhyay, Falak Saiyed, Huma Saiyad, Swarnim Rathod
{"title":"Prediction of post-operative complications among diabetic patients undergoing major surgery using biomarkers.","authors":"Jekee Patel, Parin Patel, Himarshi Upadhyay, Falak Saiyed, Huma Saiyad, Swarnim Rathod","doi":"10.6026/973206300211543","DOIUrl":null,"url":null,"abstract":"<p><p>Evaluation of pre-operative HbA1c, CRP, IL-6, and procalcitonin levels among 150 diabetic patients undergoing major surgery is of interest. Elevated HbA1c (>8%) and CRP were strongly associated with postoperative complications such as wound infections and prolonged ICU stay. IL-6 and procalcitonin show moderates predictive accuracy for systemic inflammation. Biomarker profiling proved useful for identifying high-risk patients. Incorporating these tests can improve surgical planning and postoperative care.</p>","PeriodicalId":8962,"journal":{"name":"Bioinformation","volume":"21 6","pages":"1543-1546"},"PeriodicalIF":1.9000,"publicationDate":"2025-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12449550/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Bioinformation","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.6026/973206300211543","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/1/1 0:00:00","PubModel":"eCollection","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
Evaluation of pre-operative HbA1c, CRP, IL-6, and procalcitonin levels among 150 diabetic patients undergoing major surgery is of interest. Elevated HbA1c (>8%) and CRP were strongly associated with postoperative complications such as wound infections and prolonged ICU stay. IL-6 and procalcitonin show moderates predictive accuracy for systemic inflammation. Biomarker profiling proved useful for identifying high-risk patients. Incorporating these tests can improve surgical planning and postoperative care.