American journal of infection control最新文献

{"title":"Inactivating effect of 222-nm far ultraviolet-C radiation on nontuberculous mycobacteria","authors":"Chiaki Kajiwara PhD ,&nbsp;Rena Kaigome BS ,&nbsp;Masahiro Sasaki BE ,&nbsp;Toru Koi PhD ,&nbsp;Kazuhiro Tateda MD, PhD","doi":"10.1016/j.ajic.2025.02.009","DOIUrl":"10.1016/j.ajic.2025.02.009","url":null,"abstract":"<div><div>Nontuberculous mycobacteria (NTM) are ubiquitous and can be inhaled from household water sources, posing a potential risk of pulmonary NTM disease. Exposure to 222-nm far ultraviolet-C shows comparable inactivation efficiency to 254-nm ultraviolet-C, while employing specialized optical filters to significantly enhance safety for human skin and eyes. Exposure of NTM to 222-nm far ultraviolet-C radiation demonstrated an irradiance-dependent inactivating effect, highlighting its potential as a safe and effective for water disinfection.</div></div>","PeriodicalId":7621,"journal":{"name":"American journal of infection control","volume":"53 6","pages":"Pages 729-731"},"PeriodicalIF":3.8,"publicationDate":"2025-02-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143466661","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Advanced photohydrolysis technology demonstrates rapid inactivation of aerosolized SARS-CoV-2 and efficacy against other respiratory viral pathogens","authors":"Jennifer E. Peel MPH ,&nbsp;Elizabeth Jardinella BS ,&nbsp;Yue Qu PhD ,&nbsp;Jessica A. Plante PhD ,&nbsp;Brooke M. Mitchell BS ,&nbsp;Jordyn L. Walker BA ,&nbsp;Roberto P. Garofalo MD ,&nbsp;Scott C. Weaver PhD ,&nbsp;Kenneth S. Plante PhD ,&nbsp;Trevor Brasel PhD ,&nbsp;William S. Lawrence PhD","doi":"10.1016/j.ajic.2025.02.008","DOIUrl":"10.1016/j.ajic.2025.02.008","url":null,"abstract":"<div><div>Efficient, rapid means of air decontamination are needed against widespread respiratory pathogens such as SARS-CoV-2, the virus that causes COVID-19. This study demonstrated the efficacy of advanced photohydrolysis technology in significantly reducing infectious, aerosolized SARS-CoV-2, achieving over 99% viral inactivation. Proof-of-concept assessments for respiratory syncytial virus and monkeypox virus showed similar results, suggesting broad applicability. These findings highlight the potential of the novel technology to enhance air purification and infection control strategies against multiple airborne viral pathogens.</div></div>","PeriodicalId":7621,"journal":{"name":"American journal of infection control","volume":"53 6","pages":"Pages 726-728"},"PeriodicalIF":3.8,"publicationDate":"2025-02-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143456834","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Importance of dosing: Analysis of touch-free hand hygiene dispensers for consistency","authors":"Nicole M. Smith MBA ,&nbsp;Száva Bánsághi PhD ,&nbsp;Nanshan Chen MS ,&nbsp;Travis B. Neal MPH ,&nbsp;John J. McNulty BSME ,&nbsp;Tamás P. Haidegger PhD ,&nbsp;James W. Arbogast PhD","doi":"10.1016/j.ajic.2025.02.007","DOIUrl":"10.1016/j.ajic.2025.02.007","url":null,"abstract":"<div><h3>Background</h3><div>We investigated 5 touch-free automatic foam alcohol-based handrub (ABHR) hand hygiene dispensers common in US hospitals. Output dosing was evaluated for consistency to comply with the Leapfrog 2022 guidance requirement of ≥<!--> <!-->1.0<!--> <!-->mL per ABHR dispense.</div></div><div><h3>Methods</h3><div>Fifteen dispensers and 32 distinct refills were tested, with &gt;<!--> <!-->10,000 dispenses analyzed for 5 different dispensing systems. Automated testing used computer programming and mechatronics to activate the dispensers and capture output weights at predetermined delay patterns. Low, medium, and high usage patterns per day were set with dispense delay patterns. In another laboratory, dispensers were activated manually for measurements; 50 doses were collected and weighed within an hour for each refill.</div></div><div><h3>Results</h3><div>Three of the dispenser systems had mean output &gt;<!--> <!-->1.0 mL, and 2 were &lt;<!--> <!-->1.0 mL. Two dispensers have significantly greater variability, which is driven by the foam pump design.</div></div><div><h3>Conclusions</h3><div>It was discovered that usage/testing patterns impact dosing performance. The dispenser design and engineering cause significant differences in volume dispensed and consistency across dispenses. Using sufficient ABHR to cover hands completely and keeping hands wet long enough to significantly reduce pathogens is an important requirement. Facilities should assess ABHR dispenser outputs and consider consistent dosing as an essential performance criterion for effective hand hygiene policies and practices.</div></div>","PeriodicalId":7621,"journal":{"name":"American journal of infection control","volume":"53 6","pages":"Pages 696-700"},"PeriodicalIF":3.8,"publicationDate":"2025-02-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143456836","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Understanding context to plan antimicrobial stewardship: A mixed-method study in a Brazilian urban primary care","authors":"Letícia Fernandes de Britto-Costa PhD ,&nbsp;Vítor Falcão de Oliveira PhD ,&nbsp;Maria Tereza Pepe Razzolini PhD ,&nbsp;Fátima L.S. Nunes PhD ,&nbsp;Gabriela Tonon de Oliveira Xavier MSc ,&nbsp;Erika Regina Manuli MSc ,&nbsp;Fábio Eudes Leal PhD ,&nbsp;Regina Maura Zetone Grespan BSc ,&nbsp;Cibele Cristine Remondes Sequeira BSc ,&nbsp;Meiryellen Midiã Macedo RN ,&nbsp;Ester Cerdeira Sabino PhD ,&nbsp;Alison Holmes PhD ,&nbsp;Silvia Figueiredo Costa PhD ,&nbsp;Anna S. Levin PhD ,&nbsp;Maria Clara Padoveze PhD ,&nbsp;on behalf of CAMO-Net Brazil Study Group","doi":"10.1016/j.ajic.2025.02.005","DOIUrl":"10.1016/j.ajic.2025.02.005","url":null,"abstract":"<div><h3>Background</h3><div>The Centres for Antimicrobial Optimization Network Brazil aims to implement an antimicrobial stewardship program in Brazilian municipality. This study explores barriers and enablers to its implementation, through understanding the context and beliefs regarding antimicrobial use in this environment.</div></div><div><h3>Methods</h3><div>The study occurred in 12 primary health care units, where a mixed-method study was conducted. A total of 208 out of 450 health care workers completed a Theoretical Domain Framework-based survey, and 16 patients and 12 health workers were interviewed. Survey results were compared by professional category; interviews were analyzed using Critical Discourse Analysis.</div></div><div><h3>Results</h3><div>Professionals with higher education scored higher across most domains. In the “Optimism” domain, these professionals scored ≥6.0, while others scored ≤5.0. Similar patterns were observed in the domains “Knowledge” (≥6.0 vs ≤5.5), “Social/professional role and identity” (≥6.36 vs ≤5.79), and “Intentions” (≥6.0 vs ≤5.0). Qualitative data highlighted breaks in the continuity of care and gaps in patient knowledge about antimicrobial use. Key barriers included disparities in training, physician-centered decision-making, and patient knowledge gaps. Enablers included health care workers' willingness to learn and home caregivers' understanding of patient conditions.</div></div><div><h3>Conclusions</h3><div>The implementation of the antimicrobial stewardship program depends on addressing training disparities and leveraging health care workers' willingness to learn.</div></div>","PeriodicalId":7621,"journal":{"name":"American journal of infection control","volume":"53 5","pages":"Pages 619-627"},"PeriodicalIF":3.8,"publicationDate":"2025-02-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143432024","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Isolation precautions associated with COVID-19 infections among immunocompromised populations: A multicenter study of nine National Cancer Institute--designated Comprehensive Cancer Centers","authors":"Marie H. Wilson MSN, RN, CIC, FAPIC ,&nbsp;Jennifer Harrington MA, CIC ,&nbsp;Joanna Suh MPH, CIC ,&nbsp;Candice Fearon MSGH, BSN, RN, CIC ,&nbsp;Maggie Reavis MPH, BSN, RN, CIC, CPHQ ,&nbsp;Suwannee Srisatidnarakul MSN, RN, CIC ,&nbsp;Michelle Swetky MPH, CIC, FAPIC ,&nbsp;Nancy Warren MHA, MLT(ASCP), CIC ,&nbsp;Angela Badalucco MPH, MT(ASCP) ,&nbsp;Caitlin M. Adams Barker MSN, RN, CIC, FAPIC ,&nbsp;Shobana Nandakumar MHA, M(ASCP), CQPA ,&nbsp;Steven A. Pergam MD, MPH","doi":"10.1016/j.ajic.2025.02.002","DOIUrl":"10.1016/j.ajic.2025.02.002","url":null,"abstract":"<div><h3>Background</h3><div>Nine Comprehensive Cancer Centers sought to understand COVID-19 infection management experiences to improve future immunocompromised host guidelines.</div></div><div><h3>Methods</h3><div>Volunteers from Comprehensive Cancer Center Infection Prevention and Control (C3IC) completed 2 surveys on COVID-19 practices from March 2020 to December 2023. Three reviewers independently validated qualitative analysis of findings. Virtual meetings were leveraged to discuss findings and identify themes.</div></div><div><h3>Results</h3><div>100% (9/9) of respondents changed COVID-19-associated isolation discontinuation guidance at least once. All (9/9) included patient immune status as criterion. All (9/9) required clearance testing at some point in the pandemic, 6 of 9 (66%) continued to require clearance testing at the time of the survey. Only 1 of 9 (11%) allowed antigen testing to meet criteria. Seven isolation titles were noted across 9 institutions, despite near agreement on measures employed.</div></div><div><h3>Discussion</h3><div>Variability existed in COVID-19 management among study participants, despite serving similar populations, which may stem from limited data supporting understanding of viral transmissibility in immunocompromised hosts.</div></div><div><h3>Conclusions</h3><div>Guideline development for immunocompromised hosts, potential drivers for viral evolution, can lack clarity for consistent management of the population. Engaging subject matters in specialty populations with future guideline development will improve infection prevention in health care settings.</div></div>","PeriodicalId":7621,"journal":{"name":"American journal of infection control","volume":"53 5","pages":"Pages 596-601"},"PeriodicalIF":3.8,"publicationDate":"2025-02-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143432023","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Review of state regulations related to environmental sanitation in long-term care facilities.","authors":"Ruwan Dissanayake, Emily E Johnson, Mary E Leong, Angela M Fraser","doi":"10.1016/j.ajic.2025.02.006","DOIUrl":"10.1016/j.ajic.2025.02.006","url":null,"abstract":"<p><strong>Background: </strong>We examined how state regulations for long-term care facilities address environmental sanitation.</p><p><strong>Methods: </strong>State regulations for nursing homes and assisted living facilities across all 50 US states and the District of Columbia were sourced from government Web sites. We searched using key terms about environmental sanitation and then quantified our findings to answer 4 questions.</p><p><strong>Results: </strong>More states required infection preventionists in nursing homes (29 states) than in assisted living facilities (14 states). References for environmental service workers appeared more frequently in nursing home regulations (22 states) than in assisted living regulations (6 states). Infection control training was required more often in nursing homes (32 states) than in assisted living facilities (27 states). Gloves were the most common personal protective equipment cited, addressed in 14 state nursing home regulations and 13 state-level assisted living regulations. Only 7 state nursing home regulations and 2 assisted living regulations addressed carpet, with only 6 addressing high-touch items.</p><p><strong>Conclusions: </strong>State regulations inadequately address environmental service workers, staff training, carpets, and high-touch items. These regulatory gaps could pose significant risks to long-term care residents if infection control policies and procedures rely solely on regulatory requirements.</p>","PeriodicalId":7621,"journal":{"name":"American journal of infection control","volume":" ","pages":""},"PeriodicalIF":3.8,"publicationDate":"2025-02-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143424753","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Unseen threats: Lumens 2.0 study reveals the hidden challenges of cleaning lumened surgical instruments","authors":"Cori L. Ofstead MSPH ,&nbsp;Abigail G. Smart MPH ,&nbsp;Jill E. Holdsworth MS, CIC, FAPIC, NREMT, CRCST, CHL ,&nbsp;Brandon M. Gantt MHA, CRCST, CHL, CER, LSSGBH ,&nbsp;Larry A. Lamb AGTS ,&nbsp;Kevin M. Bush Jr DHSc, EdD, FACHE, CPPS, CPHRM, CPHQ, CIC","doi":"10.1016/j.ajic.2025.02.003","DOIUrl":"10.1016/j.ajic.2025.02.003","url":null,"abstract":"<div><h3>Background</h3><div>Surgical site infections can cause significant morbidity requiring lengthy antimicrobial treatment. Infections have been linked to surgical instruments with retained tissue and foreign debris, as the presence of blood or soil interferes with sterilization effectiveness. This study aimed to determine the prevalence of visible soil or debris inside instruments and evaluate the impact of recleaning efforts.</div></div><div><h3>Methods</h3><div>Borescopes were used to inspect lumens of instruments used for orthopedic, neurologic, or ear-nose-throat procedures. Whenever visible soil or debris was observed, the instrument was recleaned up to 3 times and reinspected to assess the impact of additional cleaning.</div></div><div><h3>Results</h3><div>Researchers performed 117 inspections (40 unique instruments, 77 reinspections). All instruments had complex lumens that impede access by brushes. Debris and discoloration or residues were observed inside 100% of instruments, with rusty patches in 95%. Some soil was removed by recleaning, but visible soil remained in most lumens and fragments of lint or brush bristles were visible upon repeat inspection.</div></div><div><h3>Conclusions</h3><div>Cleaning in accordance with the manufacturer’s instructions was not effective for lumened surgical instruments. Solutions will require collaboration between infection prevention, sterile processing, and manufacturers to evaluate risk and develop strategies for improving processing outcomes.</div></div>","PeriodicalId":7621,"journal":{"name":"American journal of infection control","volume":"53 5","pages":"Pages 537-547"},"PeriodicalIF":3.8,"publicationDate":"2025-02-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143424757","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Diagnosis of coagulase-negative Staphylococcus bacteremia in patients receiving extracorporeal membrane oxygenation","authors":"Christian B. Wells MD ,&nbsp;Erika R. O’Neil MD ,&nbsp;Michal J. Sobieszczyk MD ,&nbsp;Joseph E. Marcus MD","doi":"10.1016/j.ajic.2025.02.004","DOIUrl":"10.1016/j.ajic.2025.02.004","url":null,"abstract":"<div><h3>Background</h3><div>Coagulase-negative <em>Staphylococci</em> (CoNS) are frequently cited as the most common cause of bacteremia in patients receiving extracorporeal membrane oxygenation (ECMO), yet there is significant variability in reporting rates between centers.</div></div><div><h3>Methods</h3><div>All patients who received ECMO with CoNS isolated from blood cultures between January 2022 and March 2024 were included in this retrospective cohort study. Previously reported bacteremia definitions were applied to determine the variability in rates by definition.</div></div><div><h3>Results</h3><div>In 68 patients who received ECMO during the study period, 424 blood culture sets were obtained, of which 20 (4%) yielded CoNS in 13 (19%) patients. Only 5 (38%) patients had repeat isolation. Clinical variables, such as fever and leukocytosis, did not predict repeat positivity. Rates of CoNS varied from 0 to 15 infections per 1,000 ECMO days depending on the definition utilized.</div></div><div><h3>Conclusions</h3><div>CoNS were frequently isolated in blood cultures from patients receiving ECMO. Despite the concern for biofilm formation, most CoNS were only isolated in a single culture. With the limited utility of clinical markers and frequent false positives, clinicians should order repeat blood cultures on those with CoNS isolated from blood cultures. We propose a standardized definition for CoNS bacteremia, which entails isolations of CoNS from 2 subsequent blood cultures.</div></div>","PeriodicalId":7621,"journal":{"name":"American journal of infection control","volume":"53 5","pages":"Pages 602-606"},"PeriodicalIF":3.8,"publicationDate":"2025-02-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143412763","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comment on a recent meta-analysis of influenza vaccination and COVID-19 infection.","authors":"Antonio E Pontiroli, Ivan Zanoni, Lucia La Sala, Elena Tagliabue","doi":"10.1016/j.ajic.2025.01.020","DOIUrl":"https://doi.org/10.1016/j.ajic.2025.01.020","url":null,"abstract":"","PeriodicalId":7621,"journal":{"name":"American journal of infection control","volume":" ","pages":""},"PeriodicalIF":3.8,"publicationDate":"2025-02-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143405170","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Strategies for preventing aerosol-generated microbial contamination in dental procedures: A systematic review and meta-analysis","authors":"Ravinder S. Saini PhD ,&nbsp;Rayan Ibrahim H. Binduhayyim PhD ,&nbsp;Seyed Ali Mosaddad DDS ,&nbsp;Artak Heboyan PhD","doi":"10.1016/j.ajic.2025.02.001","DOIUrl":"10.1016/j.ajic.2025.02.001","url":null,"abstract":"<div><h3>Background</h3><div>Aerosol generation in dental practice is a significant concern in infection control. This study aimed to investigate the strategies for controlling and preventing aerosol-generated microbes during dental procedures.</div></div><div><h3>Methods</h3><div>A comprehensive literature search was performed using Preferred Reporting Items for Systematic Reviews and Meta-analysis (PRISMA) guidelines through electronic databases (PubMed, ScienceDirect, Cochrane Library, Google Scholar, and Scopus) for studies reporting interventions, including mouthwash and suction devices, that were effective against pathogens generated during dental procedures. Predefined criteria identified eligible studies. Pooled efficacy was estimated using RevMan 5.4's random-effects model.Quality assessments were performed using RoB-2.0 and the Robvis web application.</div></div><div><h3>Results</h3><div>This systematic review and meta-analysis included 19 papers. Cetylpyridinium chloride, chlorhexidine, chlorine dioxide, hydrogen peroxide, botanical medicines, and suction devices are the most used dental therapies to minimise microbial contamination. Overall, these treatments showed success with a pooled effectiveness of -46.64 (95% CI: -60.89 to -32.38, I2=100%, p&lt;0.00001).</div></div><div><h3>Conclusions</h3><div>This study emphasises the need for a multifaceted approach that uses antiseptic mouthwash and suction devices to reduce cross-contamination and infection transmission during aerosol-generated dental procedures, safeguarding patients and dental workforce.</div></div>","PeriodicalId":7621,"journal":{"name":"American journal of infection control","volume":"53 5","pages":"Pages 638-647"},"PeriodicalIF":3.8,"publicationDate":"2025-02-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143381512","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}