American journal of infection control最新文献

Erratum to "Economic burden attributable to hospital-acquired infections among tumor patients from a large regional cancer center in Southern China" [Am J Infect Control. 2024;52(8):934-940]. “华南地区大型肿瘤中心肿瘤患者医院获得性感染的经济负担”[J].中华流行病学杂志，2014;52(8):934-940。

IF 2.4 3区医学

American journal of infection control Pub Date : 2025-10-06 DOI: 10.1016/j.ajic.2025.09.011

Lihua Huang, Huacheng Ning, Xin-Chen Liu, Yongjie Wang, Chuangzhong Deng, Huan Li

引用次数: 0

Healthcare Worker Experiences with a Universal Gloving Intervention to Prevent Clostridioides difficile Infection: A Qualitative Study. 卫生保健工作者普遍戴手套干预以预防艰难梭菌感染的经验：一项定性研究。

IF 2.4 3区医学

American journal of infection control Pub Date : 2025-10-03 DOI: 10.1016/j.ajic.2025.09.020

Julie A Keating, Linda McKinley, Katherine Dolan, Helene Moriarty, Cara Ray, Nasia Safdar

{"title":"Healthcare Worker Experiences with a Universal Gloving Intervention to Prevent Clostridioides difficile Infection: A Qualitative Study.","authors":"Julie A Keating, Linda McKinley, Katherine Dolan, Helene Moriarty, Cara Ray, Nasia Safdar","doi":"10.1016/j.ajic.2025.09.020","DOIUrl":"https://doi.org/10.1016/j.ajic.2025.09.020","url":null,"abstract":"Background: Universal gloving (healthcare worker gloving for all patient contact regardless of activity or patient condition) may prevent Clostridioides difficile transmission in healthcare settings. However, healthcare worker experiences with universal gloving practices are needed to understand if and how universal gloving programs may be successfully implemented for infection prevention.Methods: As part of a cluster randomized clinical trial in Veterans Affairs inpatient units to evaluate the efficacy and acceptability of a universal gloving intervention in preventing C. difficile acquisition among patients, we interviewed healthcare workers on intervention units regarding their experience with the intervention.Results: Participants reported their experience with implementing universal gloving as well as impacts to nursing workload and workflow, patient care, and hand hygiene. They also described barriers and facilitators to universal gloving.Discussion: Universal gloving is relatively straightforward to implement as an infection prevention strategy. However, barriers, including increased time for tasks, need for cross-disciplinary communication, and glove availability and accessibility, must be addressed.Conclusions: Human factors and systems engineering methods may be useful in supporting universal gloving interventions. Additional evidence demonstrating efficacy of the intervention is also needed to support future implementations.","PeriodicalId":7621,"journal":{"name":"American journal of infection control","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2025-10-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145231412","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Estimation of Risk-Adjusted Postoperative Infection Outcomes Using Interpretable Machine Learning and Electronic Health Record Data. 使用可解释的机器学习和电子健康记录数据评估风险调整后术后感染结果。

IF 2.4 3区医学

American journal of infection control Pub Date : 2025-10-01 DOI: 10.1016/j.ajic.2025.09.015

Kathryn L Colborn, Yizhou Fei, William G Henderson, Yaxu Zhuang, Adam R Dyas, Michael E Matheny, Christina M Stuart, Robert A Meguid

{"title":"Estimation of Risk-Adjusted Postoperative Infection Outcomes Using Interpretable Machine Learning and Electronic Health Record Data.","authors":"Kathryn L Colborn, Yizhou Fei, William G Henderson, Yaxu Zhuang, Adam R Dyas, Michael E Matheny, Christina M Stuart, Robert A Meguid","doi":"10.1016/j.ajic.2025.09.015","DOIUrl":"https://doi.org/10.1016/j.ajic.2025.09.015","url":null,"abstract":"Background: This study compared risk-adjusted postoperative infection outcomes estimated by statistical models applied to electronic health record (EHR) data (\"automated\") to gold-standard manual chart review outcomes estimated by the American College of Surgeons National Surgical Quality Improvement Program (ACS-NSQIP).Materials and methods: A cohort of adult patients who had operations in nine surgical specialties at five large hospitals within one healthcare system between 2013-2019 were included. 307,335 patients underwent 441,047 unique operations. Records from 30,603 patients were linked to the local ACS-NSQIP database (97% linkage). Previously published models for estimating preoperative risk and occurrence of postoperative infections were used to estimate observed to expected event ratios (O/E) for surgical site infections, urinary tract infections, sepsis/septic shock, and pneumonia.Results: Risk-adjusted infection outcomes expressed as O/E ratios were similar when comparing EHR automated methods to manual chart review across five hospitals and four infection types. The Pearson correlation coefficient of the hospital O/E ratios was 0.77, mean absolute difference was 0.13, and 100% of the confidence intervals were overlapping. The correlations and mean absolute differences for individual infection types improved as incidence rates increased.Discussion: Parsimonious statistical models applied to EHR data can be used to accurately estimate hospital risk-adjusted postoperative infection outcomes for all operations.Conclusions: These models could be used to augment postoperative infection surveillance for hospital quality monitoring.","PeriodicalId":7621,"journal":{"name":"American journal of infection control","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145224653","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Enhancing Surgical Instrument Assembly Training through Virtual Reality: A Case Study on Laparoscopic Forceps. 利用虚拟现实技术加强手术器械装配培训：以腹腔镜手术钳为例。

IF 2.4 3区医学

American journal of infection control Pub Date : 2025-09-30 DOI: 10.1016/j.ajic.2025.09.018

Manuel Rodríguez-Matesanz, Virginia González-Díez, Gema Nieto Gómez, Cristina Diaz-Agero Pérez, Diego Moreno-Blanco, Ezequiel Hidalgo-Galache, Enrique J Gómez, Jorge Vicente-Guijarro, Patricia Sánchez-González

{"title":"Enhancing Surgical Instrument Assembly Training through Virtual Reality: A Case Study on Laparoscopic Forceps.","authors":"Manuel Rodríguez-Matesanz, Virginia González-Díez, Gema Nieto Gómez, Cristina Diaz-Agero Pérez, Diego Moreno-Blanco, Ezequiel Hidalgo-Galache, Enrique J Gómez, Jorge Vicente-Guijarro, Patricia Sánchez-González","doi":"10.1016/j.ajic.2025.09.018","DOIUrl":"https://doi.org/10.1016/j.ajic.2025.09.018","url":null,"abstract":"Background: Proper reprocessing of complex surgical instruments is essential for patient safety and infection prevention. Inadequate assembly can compromise sterilization, delay procedures, and increase the risk of healthcare-associated infections. Existing training methods for sterilization staff are often informal and lack standardization.Aim: To design and validate a virtual reality (VR) training system to improve the assembly and disassembly skills of laparoscopic forceps among healthcare professionals.Methods: We co-developed a VR training tool with clinical staff at Hospital Universitario Ramón y Cajal. The system simulates the assembly of laparoscopic instruments and provides real-time performance feedback. Thirty healthcare professionals tested the tool and completed a System Usability Scale (SUS) questionnaire to evaluate its realism, usability, and training utility.Findings: Participants rated the system highly for realism (mean 4.73/5), immersion, and ease of use. Most reported improved understanding of the instrument assembly process. Performance metrics, including errors and completion time, were collected and visualized using a desktop application. Only one participant experienced mild discomfort.Conclusion: This VR-based simulation provides a safe, engaging, and effective training environment for surgical instrument reprocessing. It addresses existing gaps in education and may contribute to improved procedural accuracy and infection prevention. Future versions will expand the tool's scope and integration in hospital training programs.","PeriodicalId":7621,"journal":{"name":"American journal of infection control","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2025-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145211302","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Occupational exposure intensity trends in Healthcare Workers: Joinpoint Regression identifies COVID-19 associated inflection point (2017-2024). 医护人员职业暴露强度趋势：连接点回归确定COVID-19相关拐点（2017-2024）

IF 2.4 3区医学

American journal of infection control Pub Date : 2025-09-30 DOI: 10.1016/j.ajic.2025.09.016

Peiyun Zhou, Bingyan Zhang, Zongke Long, Jianan Shi, Siya Meng, Fang Xue, Lan Gao, Yi Li

{"title":"Occupational exposure intensity trends in Healthcare Workers: Joinpoint Regression identifies COVID-19 associated inflection point (2017-2024).","authors":"Peiyun Zhou, Bingyan Zhang, Zongke Long, Jianan Shi, Siya Meng, Fang Xue, Lan Gao, Yi Li","doi":"10.1016/j.ajic.2025.09.016","DOIUrl":"https://doi.org/10.1016/j.ajic.2025.09.016","url":null,"abstract":"Background: Healthcare workers (HCWs) globally face substantial risks from occupational blood and body fluids (BBFs) exposure, with developing countries bearing disproportionate burdens. The COVID-19 pandemic exacerbated these risks due to PPE shortages and increased clinical demands. China's healthcare system, characterized by low workforce density and chronic HCW fatigue (53.9-82%), presents a critical context for analyzing exposure dynamics. Existing studies lack longitudinal data across pandemic phases and stratified analyses by years of service (YoS).Methods: This longitudinal study (2017-2024) analyzed 860 occupational BBFs exposures from a Chinese tertiary hospital. Data included exposure timing, job roles, service duration (stratified as junior: <5 YoS, mid-career: 5-10 YoS, senior: >10 YoS), and post-exposure management. Trends were assessed via Joinpoint Regression, while risk factors for recurrent exposures were identified through logistic regression.Results: A 2021 inflection point (95% CI: 2019-2022) marked a shift from pre-pandemic exposure intensity growth (APC= 6.76, P < 0.05) to post-2021 decline (APC= -15.55, P < 0.05). junior HCWs accounted for 71.9% of exposures. Doctors and mid-career HCWs were significantly associated with recurrent exposures. Needle stick injuries are the most common type of exposure, accounting for 72.1% of all incidents.Conclusions: Systemic vulnerabilities in understaffed healthcare systems amplify exposure risks, particularly among early-career HCWs. Although pandemic-induced safety measures may have temporarily reduced exposures, workforce shortages and role-specific hazards require tenure-stratified interventions.","PeriodicalId":7621,"journal":{"name":"American journal of infection control","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2025-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145211285","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Identifying barriers and enablers to effective infection prevention and control in residential aged care: a qualitative study using the Theoretical Domains Framework. 识别障碍和使能因素，有效地预防和控制在住宅老年护理：使用理论领域框架的定性研究。

IF 2.4 3区医学

American journal of infection control Pub Date : 2025-09-30 DOI: 10.1016/j.ajic.2025.09.014

Joanne Tropea, Jacqueline Gilbert, Noleen Bennett, Lyn-Li Lim, Kirsty L Buising, Deirdre Fetherstonhaugh, Jason C Kwong, Douglas F Johnson, Caroline Marshall, Madelaine Flynn, Paul A Yates, Craig Aboltins, Wen K Lim, Sanne Peters

{"title":"Identifying barriers and enablers to effective infection prevention and control in residential aged care: a qualitative study using the Theoretical Domains Framework.","authors":"Joanne Tropea, Jacqueline Gilbert, Noleen Bennett, Lyn-Li Lim, Kirsty L Buising, Deirdre Fetherstonhaugh, Jason C Kwong, Douglas F Johnson, Caroline Marshall, Madelaine Flynn, Paul A Yates, Craig Aboltins, Wen K Lim, Sanne Peters","doi":"10.1016/j.ajic.2025.09.014","DOIUrl":"https://doi.org/10.1016/j.ajic.2025.09.014","url":null,"abstract":"Background: Infection prevention and control (IPC) practices are crucial in residential aged care homes (RACHs), yet gaps between existing evidence-based recommendations and what is done in practice (called 'evidence -practice gaps) continue. Understanding barriers and enablers to implementing evidence-based IPC is essential for improving practice. This study aims to identify barriers and enablers to RACH staff performing evidence-based IPC practices, according to the Theoretical Domains Framework (TDF), and map these domains to associated behaviour change techniques (BCTs) to inform interventions.Methods: Semi-structured interviews were conducted with 28 staff from nine RACHs in Victoria, Australia. Interviews explored seven prioritised IPC evidence-practice gaps. The TDF guided data collection and analysis. Key domains were identified and mapped to BCTs.Results: Key enablers included knowledge of IPC importance, access to equipment and resources, skills and experience, self-confidence, visual cues, and beliefs about protecting self and others. Main barriers were related to environmental context and resources, such as limited access to hand hygiene products and personal protective equipment. Social influences and competing priorities also posed challenges. The BCTs mapping suggested focusing on environmental setup, education, and infrastructure to support effective IPC.Conclusion: Residential aged care staff reported engagement with evidence-based IPC, highlighting its importance. Barriers mainly related to environmental and resource factors. Recommended strategies based on BCTs offer actionable, resource-efficient interventions to improve IPC practice in RACHs.","PeriodicalId":7621,"journal":{"name":"American journal of infection control","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2025-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145211334","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Long term impact of the SARS-CoV2 pandemic on the acquisition rate of extended-spectrum beta-lactamase-producing Enterobacteriaceae in a medical intensive care unit. SARS-CoV2大流行对重症监护病房产广谱β -内酰胺酶肠杆菌科细菌获得率的长期影响

IF 2.4 3区医学

American journal of infection control Pub Date : 2025-09-24 DOI: 10.1016/j.ajic.2025.09.013

Mathilde Taillantou-Candau, Achille Kouatchet, Helene Le Guillou-Guillemette, Vincent Dubee, Matthieu Eveillard, Frédéric Moal, Alain Mercat, Rafael Mahieu

{"title":"Long term impact of the SARS-CoV2 pandemic on the acquisition rate of extended-spectrum beta-lactamase-producing Enterobacteriaceae in a medical intensive care unit.","authors":"Mathilde Taillantou-Candau, Achille Kouatchet, Helene Le Guillou-Guillemette, Vincent Dubee, Matthieu Eveillard, Frédéric Moal, Alain Mercat, Rafael Mahieu","doi":"10.1016/j.ajic.2025.09.013","DOIUrl":"https://doi.org/10.1016/j.ajic.2025.09.013","url":null,"abstract":"Background: The COVID-19 pandemic led to major changes in patient care, with enhanced hygiene possibly reducing MDR bacteria transmission, while increased nursing workload and antibiotic use may have raised the risk of MDR acquisition.Methods: A 5-year retrospective study compared ESBL-E acquisition rates in a single ICU between the pre-COVID and COVID periods.Results: Between January 2018 and December 2022, 1736 ICU patients (mean age 64 [49-79] years) were included. Admission severity was similar across periods, but ICU stay was longer during COVID (19±19 vs. 14±13 days, p<0.001), with more patients requiring mechanical ventilation (81% vs. 73%, p<0.001) for a longer duration (17±19 vs. 10±10 days, p<0.001). ESBL-E acquisition increased by 57.3% during the COVID period (14% [CI95 11.6-16.7] vs. 8.9% [CI95 7.1-11.0], p=0.001), while admission carriage rates were similar (6% vs. 8%, p=0.57). In multivariate analysis, ICU stay duration (OR=1.01 per day), mechanical ventilation >10 days, ESBL-E prevalence, and hemodialysis were associated with acquisition; noninvasive ventilation was protective.Conclusions: In our ICU, ESBL-E acquisition increased during the COVID period. Multivariate analysis linked it to length of stay, ESBL-E prevalence, mechanical ventilation >10 days, and hemodialysis. Further studies are needed to assess post-COVID trends.","PeriodicalId":7621,"journal":{"name":"American journal of infection control","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2025-09-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145172179","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Surgical site infection after colorectal surgery in a tertiary level cancer center: risk factors, clinical characteristics, and mortality. 三级肿瘤中心结直肠癌术后手术部位感染：危险因素、临床特征和死亡率。

IF 2.4 3区医学

American journal of infection control Pub Date : 2025-09-24 DOI: 10.1016/j.ajic.2025.09.012

Marco Antonio Delaye-Martinez, Gustavo Mendez-Hirata, Javier Melchor-Ruan, Patricia Cornejo-Juarez, Bertha Garcia-Pineda, Diana Vilar-Compte

{"title":"Surgical site infection after colorectal surgery in a tertiary level cancer center: risk factors, clinical characteristics, and mortality.","authors":"Marco Antonio Delaye-Martinez, Gustavo Mendez-Hirata, Javier Melchor-Ruan, Patricia Cornejo-Juarez, Bertha Garcia-Pineda, Diana Vilar-Compte","doi":"10.1016/j.ajic.2025.09.012","DOIUrl":"https://doi.org/10.1016/j.ajic.2025.09.012","url":null,"abstract":"Background: Surgical site infections (SSIs) are a common complication in colorectal surgery. In colorectal cancer (CRC), SSIs increase recurrence and mortality. This study aimed to describe the frequency, risk factors, and mortality of patients with SSIs at a cancer center.Methods: An observational, retrospective study was conducted from 2018 to 2022, including patients with CRC who underwent elective colorectal surgery. Risk factors for SSI were assessed using multivariable logistic regression analysis. A five-year survival analysis was performed using the Kaplan-Meier curves, and hazard ratios were calculated using the Cox proportional hazards method.Results: We included 712 patients; SSI occurred in 28%. Risk factors included preoperative hemoglobin ≤8.5 g/dL (OR 3.21, p=0.04) and intraoperative mean arterial blood pressure <65 mmHg (OR 5.12, p<0.001). Adequate perioperative antimicrobial prophylaxis (PAP) reduced the SSI risk (OR 0.53, p=0.04). Increased mortality was associated with surgical diversion (HR 2.54, p<0.001), hospital-acquired pneumonia (HR 4.02, p<0.001), and septic shock (HR 14.21, p<0.001). Overall 5-year survival was lower in SSI patients (70% versus 82%; log-rank, p=0.021).Conclusions: SSIs in CRC were higher compared to other series. Preoperative anemia and intraoperative low perfusion rates were strong predictors of SSI development. An adequate PAP significantly reduced SSIs. Patients with SSIs experienced higher mortality rates.","PeriodicalId":7621,"journal":{"name":"American journal of infection control","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2025-09-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145172216","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Regional Disparities and Related Factors in Knowledge, Attitude, and Practice Toward Needlestick Injuries Among Clinical Nurses: A Propensity Score-Matched Comparative Study of Chongqing Versus National-Level Data. 临床护士对针刺伤害的知识、态度和行为的地区差异及相关因素：重庆与全国数据的倾向评分匹配比较研究

IF 2.4 3区医学

American journal of infection control Pub Date : 2025-09-19 DOI: 10.1016/j.ajic.2025.09.009

Rui He, Peiliang Wu, Wenfeng Tang, Li Tan, Xia Li, Hongjie Yi, Luman Zhang, Ying Shen

{"title":"Regional Disparities and Related Factors in Knowledge, Attitude, and Practice Toward Needlestick Injuries Among Clinical Nurses: A Propensity Score-Matched Comparative Study of Chongqing Versus National-Level Data.","authors":"Rui He, Peiliang Wu, Wenfeng Tang, Li Tan, Xia Li, Hongjie Yi, Luman Zhang, Ying Shen","doi":"10.1016/j.ajic.2025.09.009","DOIUrl":"https://doi.org/10.1016/j.ajic.2025.09.009","url":null,"abstract":"Background: Needlestick injuries (NSIs) are a major occupational hazard for healthcare workers, particularly clinical nurses. Regional disparities in NSI incidence and related knowledge, attitude, and practice (KAP) remain underexplored in China.Methods: A cross-sectional online survey collected 16,070 valid responses from 34 provincial-level regions in China between November 2022 and February 2023. Propensity score matching (PSM) was applied to control for demographic differences, followed by univariate and multivariate analyses to compare KAP levels and influencing factors of NSIs.Result: After PSM, nurses in Chongqing demonstrated higher frequencies of NSI prevention training, broader adoption of needleless connectors, and more comprehensive institutional management measures (all P<0.001) compared to national counterparts. KAP scores in Chongqing were significantly superior across all domains (P<0.001), and the self-reported NSI incidence was lower (P=0.005). Multivariable analyses identified frequent training (≥3 times/year), awareness of needleless systems, and integration of NSI prevention into hospital quality control systems as independent predictors of higher KAP scores and lower NSI risk.Conclusions: Clinical nurses in Chongqing exhibited superior KAP profiles and reduced NSI incidence compared to national averages. Systematic training and institutional integration of NSI prevention emerged as critical strategies to enhance occupational safety. These findings underscore the need for standardized policy enforcement and equitable resource distribution across regions.","PeriodicalId":7621,"journal":{"name":"American journal of infection control","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2025-09-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145111839","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Impact of Ventilator-Associated Events on Clinical Outcomes in Mechanically Ventilated Patients: A Retrospective Cohort Study from a Brazilian ICU. 呼吸机相关事件对机械通气患者临床结果的影响：来自巴西ICU的回顾性队列研究。

IF 2.4 3区医学

American journal of infection control Pub Date : 2025-09-19 DOI: 10.1016/j.ajic.2025.09.008

Milena Siciliano Nascimento, Amanda Gomes Rabelo, Cesar Augusto Madid Truyts, Adriano José Pereira, Raquel Afonso Caserta, Simone Brandi, Alexandra do Rosário Toniolo, Graziela Geanfrancisco, Paula Tuma

{"title":"Impact of Ventilator-Associated Events on Clinical Outcomes in Mechanically Ventilated Patients: A Retrospective Cohort Study from a Brazilian ICU.","authors":"Milena Siciliano Nascimento, Amanda Gomes Rabelo, Cesar Augusto Madid Truyts, Adriano José Pereira, Raquel Afonso Caserta, Simone Brandi, Alexandra do Rosário Toniolo, Graziela Geanfrancisco, Paula Tuma","doi":"10.1016/j.ajic.2025.09.008","DOIUrl":"https://doi.org/10.1016/j.ajic.2025.09.008","url":null,"abstract":"Background: Mechanical ventilation is a widely used intervention for critically ill patients in intensive care units. However, it is associated with various complications. The most up-to-date method for monitoring ventilation-related complications is through Ventilator-Associated Events.Objective: To evaluate the incidence of Ventilator-Associated Events and their impact on major clinical outcomes in patients admitted to the intensive care units.Methods: This was a single-center retrospective cohort study which all the adult patients who underwent invasive mechanical ventilation were included. The Ventilator-Associated Events identification was performed using an automated algorithm based on criteria established by the Centers for Disease Control and Prevention. Clinical, demographic, and outcome data were extracted from electronic medical records.Results: A total of 709 patients were analyzed, of whom 39(5.6%) developed Ventilator-Associated Events, resulting in a rate of 5.99 per 1,000 ventilator-days. Patients with Ventilator-Associated Events had significantly longer durations of mechanical ventilation (19.7±27.4 vs. 4.7±7.9 days; p=0.002), intensive care units stay (25.1±24.7 vs. 8.7±11.1 days; p<0.001), and hospital stay (72.7±73.5 vs. 46±98 days;p<0.001).Conclusion: The occurrence of Ventilator-Associated Events was associated with significantly worse clinical outcomes. The adoption of algorithm-based automated surveillance may enhance early Ventilator-Associated Events detection, representing the first step toward implementing targeted prevention strategies.","PeriodicalId":7621,"journal":{"name":"American journal of infection control","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2025-09-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145111808","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0