Stephanie Morgenstern, Katie Thompson, Stephanie Panton, Vivian Donnelly, Sara Pau, Kat Nelson, Lauren Booth, Taylor McIlquham, Jessica Kitlas, Christina Schumacher, Aaron M Milstone, Meghan Bernier, Anna C Sick-Samuels
{"title":"Identifying high-risk central lines in critically ill children: a novel nurse-driven screening and mitigation intervention to reduce CLABSI.","authors":"Stephanie Morgenstern, Katie Thompson, Stephanie Panton, Vivian Donnelly, Sara Pau, Kat Nelson, Lauren Booth, Taylor McIlquham, Jessica Kitlas, Christina Schumacher, Aaron M Milstone, Meghan Bernier, Anna C Sick-Samuels","doi":"10.1016/j.ajic.2024.10.029","DOIUrl":"https://doi.org/10.1016/j.ajic.2024.10.029","url":null,"abstract":"<p><strong>Background: </strong>Despite strong adherence to central line associated bloodstream infection (CLABSI) infection prevention bundles, the CLABSI rate in our academic pediatric intensive care unit (PICU) and pediatric cardiac intensive unit (PCICU) remained high.</p><p><strong>Methods: </strong>We developed a novel screening tool that stratified patients' risk for CLABSI and considered risk-mitigation strategies.</p><p><strong>Results: </strong>Of 1583 screenings, 30% were classified as high-risk, 27% as moderate-risk, and 43% as low-risk. With accurate screening, the tool was 100% sensitive to patients who developed CLABSI, with a negative predictive value of 100% for low-risk screens. The CLABSI rate declined from 1.83 per 1000 catheter-days to 0.98 and 1.02 in 2021 and 2022, respectively, with unprecedented consecutive months CLABSI free. Device utilization was stable across both units, declining by 22% in the PICU and rising in the PCICU with increased cardiac surgeries. Clinicians expressed increased awareness of patient CLABSI risk factors and mitigation strategies in surveys.</p><p><strong>Discussions: </strong>This novel screening tool effectively identified high-risk patients to target resources and promoted improvements in CLABSI-prevention processes in the PICU and PCICU.</p><p><strong>Conclusions: </strong>A novel nurse-driven CLABSI risk factor screening tool identified and focused resources on patients at high-risk for CLABSI, and increased awareness and proactive risk mitigation by clinicians.</p>","PeriodicalId":7621,"journal":{"name":"American journal of infection control","volume":null,"pages":null},"PeriodicalIF":3.8,"publicationDate":"2024-11-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142589850","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ann Gaffney, Edmond G Smyth, Zena Moore, Declan Patton, Tom O Connor, Rosemarie Derwin
{"title":"Role of admission rapid antigen testing (RATs) for COVID-19 on patients transferred from acute hospitals to a post-acute rehabilitation setting.","authors":"Ann Gaffney, Edmond G Smyth, Zena Moore, Declan Patton, Tom O Connor, Rosemarie Derwin","doi":"10.1016/j.ajic.2024.10.031","DOIUrl":"https://doi.org/10.1016/j.ajic.2024.10.031","url":null,"abstract":"<p><strong>Background: </strong>Rapid antigen tests (RATs) are suitable for point-of -care testing, require no laboratory time and give immediate results. However, are RATs useful for detecting asymptomatic COVID-19 infection when compared with polymerase chain reaction (PCR) testing in healthcare settings?</p><p><strong>Aim: </strong>The aim of this study was to implement a reliable testing system utilising RATs to promptly detect COVID-19 infection in predominantly asymptomatic patients transferred from acute hospitals to a post-acute rehabilitation unit (PARU).</p><p><strong>Methods: </strong>RAT testing was carried out on all new admissions without a history of confirmed Covid-19 infection within three months of admission. PCR testing was carried out on all patients with a positive RAT for confirmation purposes. The cycle threshold (Ct) values of COVID-19 detected results on PCR testing were examined to determine the utility of the RATs.</p><p><strong>Results: </strong>A total of 1,403 patients were transferred to the PARU from January to December 2023. The results of the study revealed an 85% accuracy of RATs with a 15% rate of false negative results at the time of admission. All patients that had a positive RAT at the time of admission also had a positive PCR test.</p><p><strong>Conclusion: </strong>This testing algorithm resulted in early detection and prompt isolation of positive cases reducing the likely spread of COVID-19 infection, hospital outbreaks and bed/ward closures.</p>","PeriodicalId":7621,"journal":{"name":"American journal of infection control","volume":null,"pages":null},"PeriodicalIF":3.8,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142567628","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Lacey Kovar, Courtney McPherson, Jennifer Ware, Lacye Hurst, Chris Gould, Amanda Martinez, Prakash Shrestha, John E Sparks
{"title":"Interventions Implemented to Remediate Mold Identified in Neonatal Intensive Care Unit (NICU) Incubators, 2022-2023.","authors":"Lacey Kovar, Courtney McPherson, Jennifer Ware, Lacye Hurst, Chris Gould, Amanda Martinez, Prakash Shrestha, John E Sparks","doi":"10.1016/j.ajic.2024.10.032","DOIUrl":"https://doi.org/10.1016/j.ajic.2024.10.032","url":null,"abstract":"<p><strong>Introduction: </strong>Neonatal Intensive Care Units (NICUs) utilize incubators to sustain core temperatures associated with transepidermial water loss. High relative humidity in incubators provide an environment for fungi to grow. In August 2022, mold was identified growing in eleven (85%) NICU incubators.</p><p><strong>Methods: </strong>A team assembled to address mold in incubators. The environment was addressed as a possible source of contamination by consulting an environmental specialist. The air handler, ducts, and environment were terminally cleaned. Specimens were collected from the contaminated incubators and the manufacturer reviewed cleaning practices. Experimental trials were conducted using the incubators to replicate mold growth after interventions.</p><p><strong>Results: </strong>The environmental consultant approved when the space could be reoccupied. Incubators introduced to the clean environment did not grow mold. Various fungi and/or yeast were identified in the contaminated incubators. Opportunities to improve cleaning and replacement of parts were identified by the manufacturer. September 2022-February 2023, seven experimental trials were completed after cleaning the incubators. Four (36%) of the eleven contaminated incubators were placed back in use due to no fungal growth. No patient illnesses occurred.</p><p><strong>Conclusion: </strong>The interventions implemented stopped ongoing contamination of incubators and use of previously contaminated incubators.</p>","PeriodicalId":7621,"journal":{"name":"American journal of infection control","volume":null,"pages":null},"PeriodicalIF":3.8,"publicationDate":"2024-10-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142563760","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Herdiantri Sufriyana, Chieh Chen, Hua-Sheng Chiu, Pavel Sumazin, Po-Yu Yang, Jiunn-Horng Kang, Emily Chia-Yu Su
{"title":"Estimating individual risk of catheter-associated urinary tract infections using explainable artificial intelligence on clinical data.","authors":"Herdiantri Sufriyana, Chieh Chen, Hua-Sheng Chiu, Pavel Sumazin, Po-Yu Yang, Jiunn-Horng Kang, Emily Chia-Yu Su","doi":"10.1016/j.ajic.2024.10.027","DOIUrl":"https://doi.org/10.1016/j.ajic.2024.10.027","url":null,"abstract":"<p><strong>Background: </strong>Catheter-associated urinary tract infections (CAUTIs) increase clinical burdens. Identifying the high-risk patients is crucial. We aimed to develop and externally validate an explainable, prognostic prediction model of CAUTIs among hospitalized individuals receiving urinary catheterization.</p><p><strong>Methods: </strong>A retrospective cohort paradigm was applied for model development and validation using data from two hospitals and used the third hospital's data for external validation. Machine learning algorithms were applied for predictive modeling. We evaluated the calibration, clinical utility, and discrimination ability to choose the best model by the validation set. The best model was assessed for the explainability.</p><p><strong>Results: </strong>We included 122,417 instances from 20-to-75-year-old subjects. Fourteen predictors were selected from 20 candidates. The best model was the RF for prediction within 6 days. It detected 97.63% (95% confidence interval [CI]: ±0.06%) CAUTI positive, and 97.36% (95% CI: ±0.07%) of individuals that were predicted to be CAUTI negative were true negatives. Among those predicted to be CAUTI positives, we expected 22.85% (95% CI: ±0.07%) of them to truly be high-risk individuals. We provide a web-based application and a paper-based nomogram for using this model.</p><p><strong>Conclusions: </strong>Our prediction model accurately detected most CAUTI positive cases, while most predicted negative individuals were correctly ruled out.</p>","PeriodicalId":7621,"journal":{"name":"American journal of infection control","volume":null,"pages":null},"PeriodicalIF":3.8,"publicationDate":"2024-10-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142556933","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Becoming Hand Hygiene Heroes: implementation of an infection prevention and control campaign for patient and family hospital safety.","authors":"Brooke Cheng, Mavis Chan, Danielle AbiFarrage, Melissa Braschel, Pamela Harrison, Jocelyn A Srigley","doi":"10.1016/j.ajic.2024.10.026","DOIUrl":"https://doi.org/10.1016/j.ajic.2024.10.026","url":null,"abstract":"<p><strong>Background: </strong>The COVID-19 pandemic highlighted that hand hygiene is key in preventing healthcare-associated infections. Patients and families are understudied targets for infection prevention and control practices. Previous campaigns to change hand hygiene behavior have been effective, but often face systemic challenges with implementation.</p><p><strong>Methods: </strong>The \"Hand Hygiene Heroes\" educational campaign was developed to improve patient and family hand hygiene at two tertiary care pediatric and obstetrics hospitals. Its multiple phases included visual materials, tailored activities for nine hospital units, and long-term evaluation during a two-year period. Hand hygiene rates among patients/families and healthcare workers were measured at baseline and throughout the campaign via direct observation.</p><p><strong>Results: </strong>Overall, hand hygiene significantly increased for both patients/families (OR 1.82, p 0.041) and healthcare workers (OR 2.15, p <0.001) after campaign initiation. However, individual units had varying degrees of sustainment on follow-up evaluations.</p><p><strong>Discussion: </strong>Duration of intervention, activity simplicity, active participation, and resource availability may affect success of campaign initiatives. Positive prognostic factors included mixed leadership support from administration and front-line workers, pre-determined sustainability plans, and tailored activities by target audience.</p><p><strong>Conclusions: </strong>Implementation of hospital educational campaigns can be resource-intensive but can positively impact patient and family hand hygiene.</p>","PeriodicalId":7621,"journal":{"name":"American journal of infection control","volume":null,"pages":null},"PeriodicalIF":3.8,"publicationDate":"2024-10-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142567619","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Occupational exposure to Blood and Body Fluids among Healthcare Professionals in a military hospital in Greece: A retrospective single-center study.","authors":"Petroula Stamataki, Angeliki Angeletopoulou, Angeliki Chandrinou, Maria Kagialari, Konstantina Gaitanou, Marigo Tseroni","doi":"10.1016/j.ajic.2024.10.017","DOIUrl":"https://doi.org/10.1016/j.ajic.2024.10.017","url":null,"abstract":"<p><strong>Background: </strong>Healthcare Professionel (HCP) worldwide are subjected to various occupational hazards, including exposure to Blood and Body Fluids (BBF). However, with systematic training and supervision, the impact of such incidents can be significantly mitigated.</p><p><strong>Objective: </strong>This study aims to assess the incidence of occupational exposure to BBF among HCPs reported to a military hospital over a five-year period. Additionally, it seeks to explore the characteristics of the affected HCP and the conditions of exposure, and to evaluate HCP' overall compliance with the hospital's guidelines.</p><p><strong>Methods: </strong>This is a retrospective, single-center study that includes all self-reported forms submitted from January 1, 2019, to December 31, 2023.</p><p><strong>Results: </strong>The overall incidence of BBF exposure was 3.05 per 100 full-time employment-years (FTEYs) or 3.01 per 100 HCP per year, whereas the incidence of needlesticks and sharps injuries (NSSIs) was 2.73 per 100 FTEYs or 2.54 per 100 HCPs per year. Overall HCP' compliance was 34.1%, with an increase from 1.6% in 2019 to 45.9% in 2023.</p><p><strong>Conclusions: </strong>There is a need for a unified process for the collection of nationwide, longitudinal data on exposure to BBF, as well as for the development of targeted training programs on occupational health and safety for HCP.</p>","PeriodicalId":7621,"journal":{"name":"American journal of infection control","volume":null,"pages":null},"PeriodicalIF":3.8,"publicationDate":"2024-10-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142567625","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Microbial Contamination in Reusable Healthcare Bath Basins: An Observational Descriptive Study.","authors":"Barbara J Quinn, Kathleen Vollman","doi":"10.1016/j.ajic.2024.10.015","DOIUrl":"https://doi.org/10.1016/j.ajic.2024.10.015","url":null,"abstract":"<p><p>The relationship between pathogens in the healthcare environment and healthcare-acquired infection has been well-documented in the literature. No study has been published since 2012 regarding the contamination of reusable bath basins. This brief report aims to determine if basin contamination remains a reservoir for bacteria that may contribute to the risk of spreading microorganisms to vulnerable patients. We address this question with data from multiple sites over ten years.</p>","PeriodicalId":7621,"journal":{"name":"American journal of infection control","volume":null,"pages":null},"PeriodicalIF":3.8,"publicationDate":"2024-10-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142567622","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jin Li, Fang Yuan, Shengfu Fan, Jie Tian, Jianzhou Yang
{"title":"The impact of COVID-19 pandemic on reported notifiable infectious diseases in China: An interrupted time series analysis.","authors":"Jin Li, Fang Yuan, Shengfu Fan, Jie Tian, Jianzhou Yang","doi":"10.1016/j.ajic.2024.10.010","DOIUrl":"10.1016/j.ajic.2024.10.010","url":null,"abstract":"<p><strong>Background: </strong>During major public health crises, the epidemiological characteristics of commonly reported infectious diseases may change. Based on routinely reported data on notifiable infectious diseases, we investigated whether the incidence and mortality of infectious diseases in China were affected by the coronavirus disease (COVID-19).</p><p><strong>Methods: </strong>We analyzed monthly reported data on nationally notifiable infectious diseases from January 2013 to March 2024. Using an interrupted time series design, we performed Poisson regression to assess changes in the incidence and mortality rates of infectious diseases before, during, and after the COVID-19 pandemic.</p><p><strong>Results: </strong>We found that during the COVID-19 outbreak, the reported incidence of nationally notifiable infectious diseases significantly and immediately decreased (relative risk [RR]= 0.6206; 95% confidence interval [CI]= 0.6201-0.6211), and so did the mortality rate (RR=0.7814; 95% CI=0.7696-0.7933). After the end of pandemic control measures, the reported incidence surged abruptly starting from January 2023, showing a sharp rise compared with the prepandemic period (RR=1.8608; 95% CI=1.8595-1.8621). The reported mortality increased, too (RR=1.081; 95% CI=1.0638-1.0984).</p><p><strong>Conclusions: </strong>The overall incidence and mortality of infectious diseases decreased immediately after the outbreak of COVID-19. After the end of pandemic control measures, their incidence rate sharply increased, and their mortality rate also rose.</p>","PeriodicalId":7621,"journal":{"name":"American journal of infection control","volume":null,"pages":null},"PeriodicalIF":3.8,"publicationDate":"2024-10-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142492965","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Elizabethkingia Meningoseptica in Dubai, United Arab Emirates: A 7-Year Multicenter Study.","authors":"Hawra Ali Hussain Alsayed, Narjes Saheb Sharif-Askari, Fatemeh Saheb Sharif-Askari, Rabih Halwani","doi":"10.1016/j.ajic.2024.10.016","DOIUrl":"https://doi.org/10.1016/j.ajic.2024.10.016","url":null,"abstract":"<p><p>Elizabethkingia meningoseptica is a gram-negative bacillus. Widely distributed in nature, it poses a significant threat as a nosocomial pathogen, particularly affecting immunocompromised neonates and the elderly. This study aims to describe the antimicrobial susceptibility and outcomes of E. meningoseptica infections over seven years in UAE. A total of 23 cases were observed during the study, 21 (91%) of which exhibited multidrug resistance. More than half of the cases required intensive care and mechanical ventilation (n=13, 57%). The observed in-hospital mortality rate was 38% (n=5) in adults and 20% (n=2) in pediatrics. Effective management of E. meningoseptica infections requires vigilant monitoring, comprehensive control, and targeted therapies.</p>","PeriodicalId":7621,"journal":{"name":"American journal of infection control","volume":null,"pages":null},"PeriodicalIF":3.8,"publicationDate":"2024-10-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142492963","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}