American journal of infection control最新文献

A multicentric outbreak of Candida auris in Mexico: 2020 to 2023. 墨西哥爆发多中心念珠菌疫情：2020-2023 年。

IF 4.3 3区医学

American journal of infection control Pub Date : 2024-12-01 Epub Date: 2024-07-24 DOI: 10.1016/j.ajic.2024.07.012

Patricia Rodríguez-de la Garza, Carlos de la Cruz-de la Cruz, José Iván Castillo Bejarano, Alicia Estela López Romo, Jorge Vera Delgado, Beatriz Aguilar Ramos, Mirna Natalia Martínez Neira, Daniel Siller Rodríguez, Héctor Mauricio Sánchez Rodríguez, Omar Alejandro Rangel Selvera

{"title":"A multicentric outbreak of Candida auris in Mexico: 2020 to 2023.","authors":"Patricia Rodríguez-de la Garza, Carlos de la Cruz-de la Cruz, José Iván Castillo Bejarano, Alicia Estela López Romo, Jorge Vera Delgado, Beatriz Aguilar Ramos, Mirna Natalia Martínez Neira, Daniel Siller Rodríguez, Héctor Mauricio Sánchez Rodríguez, Omar Alejandro Rangel Selvera","doi":"10.1016/j.ajic.2024.07.012","DOIUrl":"10.1016/j.ajic.2024.07.012","url":null,"abstract":"Background: Candida auris, an emerging multidrug-resistant yeast, has become a global concern due to its association with nosocomial outbreaks and resistance to antifungal medications. The COVID-19 pandemic has exacerbated the situation, with several outbreaks reported worldwide, including in Mexico. We describe the clinical and microbiological characteristics of a multicentric outbreak in private institutions in Mexico.Methods: A retrospective observational study was conducted across 4 Christus Muguerza Hospital Health Care System facilities in Monterrey, Mexico, where simultaneous outbreaks of C auris occurred. Patients with colonization or infection with C auris between September 2020 and December 2023 were included.Results: Analysis revealed 37 cases, predominantly male (median age, 55.8years). While most cases were initially colonization, a significant proportion progressed to infection (32.4%). Patients with documented infection had longer intensive care unit and hospital stays, often requiring mechanical ventilation. Antifungal treatment varied, with empirical fluconazole being the first drug in most cases, followed by anidulafungin and caspofungin. Resistance to fluconazole was widespread, but susceptibility to other antifungals varied. The overall mortality rates were high (40.5%), with no significant difference in median survival between colonized and infected patients.Conclusions: We reported a high rate of infection in previously colonized cases associated with longer hospital lenght stay, and a high susceptibility to echinocandins.","PeriodicalId":7621,"journal":{"name":"American journal of infection control","volume":" ","pages":"1384-1389"},"PeriodicalIF":4.3,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141764830","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A survey of infection prevention and animal-assisted activity policies in health care facilities-United States, 2023. 2023 年美国医疗保健机构感染预防和动物辅助活动政策调查》（A Survey of Infection Prevention and Animal Assisted Activity Policies in Healthcare Facilities - United States, 2023）。

IF 4.3 3区医学

American journal of infection control Pub Date : 2024-12-01 Epub Date: 2024-07-02 DOI: 10.1016/j.ajic.2024.06.024

Michael A Ben-Aderet, Souci Louis, Jonathan D Grein, Susan E Beekmann, Philip M Polgreen, Daniel Z Uslan

引用次数: 0

Building statewide IP capacity in Maryland: A pilot program for talent recruitment and retention efforts. 马里兰州全州知识产权能力建设：人才招聘和保留工作试点计划》。

IF 4.3 3区医学

American journal of infection control Pub Date : 2024-12-01 Epub Date: 2024-08-24 DOI: 10.1016/j.ajic.2024.08.016

Carol McLay, Jamie Rubin, Daryl Hawkins, Bria Graham-Glover, Deanna Barker

引用次数: 0

Post-occupancy evaluation on temporary negative pressure isolation wards with portable high-efficiency particulate air filter units used during the COVID-19 pandemic in South Korea. 对韩国 COVID-19 大流行期间使用便携式高效微粒空气过滤器的临时负压隔离病房进行入住后评估。

IF 4.3 3区医学

American journal of infection control Pub Date : 2024-12-01 Epub Date: 2024-09-06 DOI: 10.1016/j.ajic.2024.08.025

Se Jin Lee, Won Seok Lee, Joo Yeon Roh, Shin Hye Lee, Eun Seok Kim, Myoung Souk Yeo

{"title":"Post-occupancy evaluation on temporary negative pressure isolation wards with portable high-efficiency particulate air filter units used during the COVID-19 pandemic in South Korea.","authors":"Se Jin Lee, Won Seok Lee, Joo Yeon Roh, Shin Hye Lee, Eun Seok Kim, Myoung Souk Yeo","doi":"10.1016/j.ajic.2024.08.025","DOIUrl":"10.1016/j.ajic.2024.08.025","url":null,"abstract":"Background: During the COVID-19 pandemic, in South Korea, several inpatient wards were converted to temporary negative pressure isolation (TNPI) wards by using portable high-efficiency particulate air filter units (PHUs). This study proposes improvements to the TNPI ward to prepare for airborne infections.Methods: Existing air-conditioning systems were investigated during the pandemic in 4 hospitals through a document review and field investigation with staff interviews. On-site experiments and measurements were conducted under vacant conditions. Differential pressure (∆P) between spaces was measured in all 4 hospitals, while tracer gas tests were carried out in 2 hospitals.Results: The investigation revealed that thermal discomfort caused the existing systems remaining perpetually active. Additionally, the noise generated by the PHU caused an unexpected shutdown of that equipment. Furthermore, the ∆P of over -2.5 Pa was measured as a result of the operating status of equipment. These situations can cause duct backflow and gas diffusion through unsealed diffusers. Moreover, low airtightness of existing facilities can affect indoor environment, pressure difference, and gas diffusion.Conclusions: When using existing facilities as TNPI wards, the airtightness and existing systems should be considered. We concluded that it is important to increase the airtightness and seal unused diffusers in order to prevent cross-infection by unpredictable airflow.","PeriodicalId":7621,"journal":{"name":"American journal of infection control","volume":" ","pages":"1403-1411"},"PeriodicalIF":4.3,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142153045","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The impact of a novel color additive for disinfectant wipes on room cleanliness and turnover time. 用于消毒湿巾的新型颜色添加剂对房间清洁度和周转时间的影响。

IF 4.3 3区医学

American journal of infection control Pub Date : 2024-12-01 Epub Date: 2024-09-19 DOI: 10.1016/j.ajic.2024.07.009

Olayinka Oremade, Barbara Odac, Jinzy George, Frederick Browne

{"title":"The impact of a novel color additive for disinfectant wipes on room cleanliness and turnover time.","authors":"Olayinka Oremade, Barbara Odac, Jinzy George, Frederick Browne","doi":"10.1016/j.ajic.2024.07.009","DOIUrl":"10.1016/j.ajic.2024.07.009","url":null,"abstract":"Background: Contaminated environmental surfaces in the health care setting put patients at risk of acquiring health care-associated infections. Highlight (Kinnos) is a novel color-additive technology for disinfectant wipes that helps users visualize surfaces that have been cleaned by producing a transient color on wiped surfaces that fades off after effective cleaning.Methods: To quantify the impact of real-time visual feedback on room cleanliness and efficiency, a pre-post quasi-experimental study was conducted by comparing Replicate Organism Detection and Counting (RODAC) plate counts and room turnaround times with and without the use of the color additive.Results: Compared with the control group of disinfectant alone, disinfection with the color additive resulted in a 69.2% improvement in room cleanliness accompanied by a 5.9% faster room turnover time.Discussion: As far as we know, this study is the first to publish on the impact of a novel color additive on the environment of care as measured by microbial culturing and room turnaround times, finding advantages in both metrics relative to the status quo.Conclusions: The use of real-time visual feedback can improve the thoroughness of disinfection cleaning while maintaining operational efficiency.","PeriodicalId":7621,"journal":{"name":"American journal of infection control","volume":" ","pages":"1366-1370"},"PeriodicalIF":4.3,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142279014","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Efficacy of powered air-purifying respirators (PAPRs) for source control of simulated respiratory aerosols. 电动空气净化呼吸器（PAPRs）在模拟呼吸气溶胶源控制方面的功效。

IF 4.3 3区医学

American journal of infection control Pub Date : 2024-12-01 Epub Date: 2024-08-06 DOI: 10.1016/j.ajic.2024.07.019

William G Lindsley, Francoise M Blachere, Raymond C Derk, Anna Mnatsakanova, John D Noti

{"title":"Efficacy of powered air-purifying respirators (PAPRs) for source control of simulated respiratory aerosols.","authors":"William G Lindsley, Francoise M Blachere, Raymond C Derk, Anna Mnatsakanova, John D Noti","doi":"10.1016/j.ajic.2024.07.019","DOIUrl":"10.1016/j.ajic.2024.07.019","url":null,"abstract":"Background: Loose-fitting powered air-purifying respirators (PAPRs) are a popular alternative to the use of filtering facepiece respirators for health care workers. Although PAPRs protect the wearer from aerosol particles, their ability to block infectious aerosol particles exhaled by the wearer from being released into the environment (called source control) is unclear.Methods: The source control performance of 4 PAPRs with loose-fitting facepieces were tested using a manikin that exhales aerosol particles. The PAPRs were tested by themselves and in combination with a face-worn product intended to provide source control (either a surgical mask or an N95 filtering facepiece respirator).Results: Two PAPR facepieces with filtration panels significantly reduced the release of exhaled aerosols into the environment, while 3 facepieces without such panels did not. Wearing a surgical mask or respirator under the facepiece significantly improved the source control performance.Conclusions: Most PAPR facepieces do not block aerosols exhaled by the wearer. Facepieces designed to filter exhaled particles can prevent aerosols from being released into the environment. Wearing a surgical mask or a filtering facepiece respirator under the facepiece can also provide source control, but PAPRs are not typically certified for use with masks and respirators.","PeriodicalId":7621,"journal":{"name":"American journal of infection control","volume":" ","pages":"1397-1402"},"PeriodicalIF":4.3,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141905600","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

SARS-CoV-2 surveillance testing and isolation management of immunocompromised patients: Survey results from 13 health care centers in the United States. SARS-CoV-2 监控测试和免疫力低下患者的隔离管理 - 来自美国 13 家医疗保健中心的调查结果。

IF 4.3 3区医学

American journal of infection control Pub Date : 2024-12-01 Epub Date: 2024-07-23 DOI: 10.1016/j.ajic.2024.07.010

Anoshé Aslam, Mini Kamboj, Tania Bubb

引用次数: 0

Antibiotic prescription prevalence in Iranian outpatients: A focus on defined daily doses and the AWaRe classification system. 伊朗门诊患者的抗生素处方流行率：伊朗门诊病人的抗生素处方流行率：关注定义的每日剂量和 AWaRe 分类系统。

IF 4.3 3区医学

American journal of infection control Pub Date : 2024-12-01 Epub Date: 2024-07-18 DOI: 10.1016/j.ajic.2024.07.007

Mohammad Mahdi Nasehi, Mohammad Effatpanah, Mohammad Gholamnezhad, Hossein Karami, Maryam Ghamkhar, Nezam Armand, Yasmin Heydarzadeh Sohi, Reza Mehrizi, Leila Ghamkhar

{"title":"Antibiotic prescription prevalence in Iranian outpatients: A focus on defined daily doses and the AWaRe classification system.","authors":"Mohammad Mahdi Nasehi, Mohammad Effatpanah, Mohammad Gholamnezhad, Hossein Karami, Maryam Ghamkhar, Nezam Armand, Yasmin Heydarzadeh Sohi, Reza Mehrizi, Leila Ghamkhar","doi":"10.1016/j.ajic.2024.07.007","DOIUrl":"10.1016/j.ajic.2024.07.007","url":null,"abstract":"Background: The inappropriate use and overprescription of antibiotics pose a global health threat, particularly contributing to antimicrobial resistance. This study aims to evaluate antibiotic prescription prevalence in Iranian outpatients using the defined daily doses (DDD) and Access, Watch, and Reserve classification systems.Methods: This retrospective study analyzed electronic prescriptions for systemic antibiotics in Tehran, Iran, from March 2022 to March 2023. The data were obtained from the Iranian Health Insurance Organization and processed using the Cross-Industry Standard Process. Descriptive statistics and DDD per 1,000 inhabitants per day were calculated.Results: A total of 817,178 antibiotic prescriptions were analyzed, with a sex distribution of 57.43% female and a median age of 48 years. On average, each patient received 1.89 antibiotics per prescription. Over 63% of antibiotics were classified in the \"Watch\" category, with Azithromycin being the most commonly prescribed (27.56%). The total DDD per 1,000 inhabitants per day was 4.99, with general practitioners accounting for 58.02% of the prescriptions, primarily prescribing Azithromycin.Conclusions: The study emphasizes the high use of Watch group antibiotics, indicating a need for improved prescribing practices. Education on antibiotic stewardship and stricter guidelines are necessary to combat antimicrobial resistance. Continuous monitoring is crucial to optimize antibiotic use in outpatient settings in Iran.","PeriodicalId":7621,"journal":{"name":"American journal of infection control","volume":" ","pages":"1359-1365"},"PeriodicalIF":4.3,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141733310","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Retrospective, propensity score--matched study examining the relationship between frailty and Clostridioides difficile infection in a national cohort of US veterans. 在美国退伍军人全国队列中开展倾向得分匹配回顾性研究，探讨虚弱与艰难梭菌感染之间的关系。

IF 4.3 3区医学

American journal of infection control Pub Date : 2024-12-01 Epub Date: 2024-08-26 DOI: 10.1016/j.ajic.2024.08.020

Kelly R Reveles, Kelsey A Strey, Esther L Albuquerque, Damaris Jacota, Xavier Jones, Joseph J Carreno

{"title":"Retrospective, propensity score--matched study examining the relationship between frailty and Clostridioides difficile infection in a national cohort of US veterans.","authors":"Kelly R Reveles, Kelsey A Strey, Esther L Albuquerque, Damaris Jacota, Xavier Jones, Joseph J Carreno","doi":"10.1016/j.ajic.2024.08.020","DOIUrl":"10.1016/j.ajic.2024.08.020","url":null,"abstract":"Background: Frailty is often more predictive of disease and mortality compared with chronological age. This study determined the impact of frailty on Clostridioides difficile infection (CDI) risk and outcomes in a national veteran population.Methods: This was a retrospective cohort study of CDI and control veteran inpatients and outpatients from fiscal year 2003 to 2018. Baseline frailty was presented as the Veterans Affairs (VA) Frailty Index. Propensity score--matched analyses were conducted to compare CDI risk, CDI health outcomes, and 1-year new-onset frailty-associated conditions.Results: A total of 11,451 CDI and 11,451 matched control patients were included. Baseline frailty conditions were more common among CDI patients, especially involuntary weight loss (6.0% vs 3.4%, P < .001) and anemia (24.6% vs 18.7%, P < .001). VA Frailty Index was significantly higher for CDI patients (0.13 vs 0.11, P = .019). Frail CDI patients were more likely to experience 30-day mortality (11.3% vs 1.1%, P < .001) and 60-day CDI recurrence (20.4% vs 16.3%, P < .001) compared with non-/prefrail CDI patients. At 1year, CDI patients were significantly more likely to be categorized as frail (19.6% vs 17.0%, P < .001).Conclusions: This study demonstrated the potential association between frailty and CDI risk and health outcomes, as well as new-onset frailty diagnoses in patients who develop CDI.","PeriodicalId":7621,"journal":{"name":"American journal of infection control","volume":" ","pages":"1412-1418"},"PeriodicalIF":4.3,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142091397","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Clinical impact of active screening cultures for carbapenem-resistant Acinetobacter baumannii: A systematic review and meta-analysis. 积极筛选培养以减少耐碳青霉烯类鲍曼不动杆菌引起的感染：系统综述和荟萃分析。

IF 4.3 3区医学

American journal of infection control Pub Date : 2024-12-01 Epub Date: 2024-06-25 DOI: 10.1016/j.ajic.2024.06.017

Ili Margalit, Digbijay Kunwar, Chen Gadot, Marco Meroi, Rebecca Scardellato, Amber Zamir, Anastasia Koutsolioutsou, Elad Goldberg, Elda Righi, Dafna Yahav

{"title":"Clinical impact of active screening cultures for carbapenem-resistant Acinetobacter baumannii: A systematic review and meta-analysis.","authors":"Ili Margalit, Digbijay Kunwar, Chen Gadot, Marco Meroi, Rebecca Scardellato, Amber Zamir, Anastasia Koutsolioutsou, Elad Goldberg, Elda Righi, Dafna Yahav","doi":"10.1016/j.ajic.2024.06.017","DOIUrl":"10.1016/j.ajic.2024.06.017","url":null,"abstract":"Background: Carbapenem-resistant Acinetobacter baumannii (CRAB) has emerged as a significant health care-associated infection carrying substantial mortality. We assessed the clinical impact of active screening cultures for CRAB.Methods: A systematic review and meta-analysis, aiming to answer 2 questions: (1) Does screening versus no screening improve clinical outcomes? (2) Does positive screening (\"CRAB carrier\") predict CRAB infections? We searched the literature until January 2024 for comparative studies reporting clinical outcomes (mortality, invasive CRAB infections).Results: Of 5,407 screened publications, 9 studies (10,865 individuals) were included. Invasive CRAB infection rate was significantly higher among CRAB carriers (OR 11.14, 95% CI 4.95-25.05, with substantial heterogeneity stemming from size rather than direction of the effect). Negative predictive value of noncarriage for invasive infection was 97%. CRAB bloodstream infection rate was significantly higher among carriers (odds ratio 16.23, 95% confidence interval 2.9-110.08). No difference was demonstrated between the groups for CRAB ventilator-associated pneumonia, length of stay, and mortality. Only 1 study reported outcomes for study question #1.Conclusions: Data to support active CRAB screening are scarce regarding its clinical benefit for patients. Positively screened patients are at significantly higher risk for invasive CRAB infections, with high negative predictive value for noncarriage. This did not translate to reduced mortality.","PeriodicalId":7621,"journal":{"name":"American journal of infection control","volume":" ","pages":"1351-1358"},"PeriodicalIF":4.3,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141465602","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0