American journal of infection control最新文献_第10页

Challenges and trends in Gram-negative bacterial infections in critically neonates: A seven-and-a-half-year observational study 重症新生儿革兰氏阴性菌感染的挑战与趋势：一项为期七年半的观察研究。

IF 3.8 3区医学

American journal of infection control Pub Date : 2025-01-01 DOI: 10.1016/j.ajic.2024.08.004

Isadora Caixeta da Silveira Ferreira , Izabella Clara de Brito Machado , Ralciane de Paula Menezes , Thiago Alves de Jesus , Mallu Santos Mendonça Lopes , Lúcio Borges de Araújo , Daniela Marques de Lima Mota Ferreira , Denise Von Dolinger de Brito Röder

{"title":"Challenges and trends in Gram-negative bacterial infections in critically neonates: A seven-and-a-half-year observational study","authors":"Isadora Caixeta da Silveira Ferreira , Izabella Clara de Brito Machado , Ralciane de Paula Menezes , Thiago Alves de Jesus , Mallu Santos Mendonça Lopes , Lúcio Borges de Araújo , Daniela Marques de Lima Mota Ferreira , Denise Von Dolinger de Brito Röder","doi":"10.1016/j.ajic.2024.08.004","DOIUrl":"10.1016/j.ajic.2024.08.004","url":null,"abstract":"<div><h3>Background</h3><div>Analyze the incidence, risk factors, and fatality rates of bloodstream infections by Gram-negative bacteria (GNB-BSIs) in a Neonatal Intensive Care Unit.</div></div><div><h3>Methods</h3><div>This study employs a retrospective cohort design utilizing records of neonates admitted to the Neonatal Intensive Care Unit between January 2015 and June 2022.</div></div><div><h3>Results</h3><div>Among 1,495 neonates, 5.2% developed GNB-BSIs. The average incidence of infection per 1,000 patient-days was 2.9. Primary risk factors for infection that included preceeding carbapenem use were significant risk factors (odds ratio=514.4; <em>P</em> < .01) and fourth-generation cephalosporins (odds ratio=66; <em>P</em> < .01). Among the 85 GNB, 75.3% were fermenters, and 24.7% were non-fermenters. Of the isolates, 14.1% produced extended-spectrum beta-lactamase, and 2.3% carbapenem-resistant. Infection correlated with prolonged hospital stays (10-39days) and increased mortality (10%-29.9%).</div></div><div><h3>Conclusions</h3><div>The high incidence of GNB-BSIs was exacerbated by the preceeding use of broad-spectrum antimicrobials, increasing the presence of multidrug-resistant isolates and fatality rates. These findings emphasize the importance of active surveillance.</div></div>","PeriodicalId":7621,"journal":{"name":"American journal of infection control","volume":"53 1","pages":"Pages 13-21"},"PeriodicalIF":3.8,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141915850","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Long-lasting effects of control measures on trends in incidence in neonatal late-onset sepsis due to multiresistant bacteria in a Brazilian neonatal unit 巴西新生儿病房多重耐药菌引起的新生儿晚期败血症发病率趋势的长期控制措施效果。

IF 3.8 3区医学

American journal of infection control Pub Date : 2025-01-01 DOI: 10.1016/j.ajic.2024.08.007

Ivan Gilberto Macolla Bazan MD , Barbara Barros Pereira Lobo MD , Angelica Zaninelli Schreiber PhD , Roseli Calil PhD , Sergio Tadeu Martins Marba PhD , Jamil Pedro de Siqueira Caldas PhD

{"title":"Long-lasting effects of control measures on trends in incidence in neonatal late-onset sepsis due to multiresistant bacteria in a Brazilian neonatal unit","authors":"Ivan Gilberto Macolla Bazan MD , Barbara Barros Pereira Lobo MD , Angelica Zaninelli Schreiber PhD , Roseli Calil PhD , Sergio Tadeu Martins Marba PhD , Jamil Pedro de Siqueira Caldas PhD","doi":"10.1016/j.ajic.2024.08.007","DOIUrl":"10.1016/j.ajic.2024.08.007","url":null,"abstract":"<div><h3>Background</h3><div>In response to a 1995 outbreak of sepsis caused by multidrug-resistant (MR) Gram-negative bacteria (GNB), a Brazilian level III neonatal unit established a series of control and prevention measures. This study evaluated the long-term effects of these measures on late-onset neonatal sepsis (LONS) caused by MR bacteria from 2000 to 2020 and examined their impact on in-hospital mortality.</div></div><div><h3>Methods</h3><div>Newborns with LONS and positive cultures for <em>Staphylococcus aureus</em>, GNB, and <em>Enterococcus sp</em> were selected, adhering to Center for Desease Control and Prevention and local criteria. Joinpoint regression analysis was used to assess annual trends.</div></div><div><h3>Results</h3><div>Over the 21-year period, the overall LONS rate was 4.6%, showing a significant decline from 2000 to 2016 (<em>P</em> < .0001, slope -0.36). However, from 2016 to 2020, there was a non-significant increase in sepsis rates (slope +0.92, <em>P</em> = .08). MR sepsis were in 15.8% of sepsis cases and displayed a non-significant upward trend (slope +0.50, <em>P</em> = .08) with no major shifts. In-hospital mortality rates for MR and non-MR LONS showed no significant differences (<em>P</em> = .413).</div></div><div><h3>Discussion</h3><div>The study indicates a low prevalence of MR sepsis due to effective antimicrobial use and educational interventions.</div></div><div><h3>Conclusions</h3><div>MR sepsis prevalence remained low and stable, not increasing in-hospital mortality.</div></div>","PeriodicalId":7621,"journal":{"name":"American journal of infection control","volume":"53 1","pages":"Pages 22-29"},"PeriodicalIF":3.8,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141987243","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Effectiveness of sensing gloves–applied virtual reality education system on hand hygiene practice: A randomized controlled trial 感知手套应用虚拟现实教育系统对手部卫生实践的效果：随机对照试验

IF 3.8 3区医学

American journal of infection control Pub Date : 2025-01-01 DOI: 10.1016/j.ajic.2024.08.003

Mahiro Izumi , Hideharu Hagiya MD, PhD , Yuki Otsuka MD, PhD , Yoshiaki Soejima MD, PhD , Shinnosuke Fukushima MD, PhD , Mitsunobu Shibata , Satoshi Hirota , Toshihiro Koyama PhD , Fumio Otsuka MD, PhD , Akio Gofuku PhD

{"title":"Effectiveness of sensing gloves–applied virtual reality education system on hand hygiene practice: A randomized controlled trial","authors":"Mahiro Izumi , Hideharu Hagiya MD, PhD , Yuki Otsuka MD, PhD , Yoshiaki Soejima MD, PhD , Shinnosuke Fukushima MD, PhD , Mitsunobu Shibata , Satoshi Hirota , Toshihiro Koyama PhD , Fumio Otsuka MD, PhD , Akio Gofuku PhD","doi":"10.1016/j.ajic.2024.08.003","DOIUrl":"10.1016/j.ajic.2024.08.003","url":null,"abstract":"<div><h3>Background</h3><div>We developed a virtual reality (VR) education system and evaluated its clinical utility for promoting hand hygiene practices.</div></div><div><h3>Methods</h3><div>This prospective, 2-week, randomized controlled study conducted at Okayama University Hospital, Japan, from November 2023 to January 2024, involved 22 participants (18 medical students and 4 residents). A fully immersive 360° VR system (VIVE Pro Eye) using a head-mounted display and sensing gloves was used to develop 3 health care tasks in a virtual patient room—Environmental Cleaning, Gauze Exchange, and Urine Collection. After monitoring all participants' baseline usage data of portable hand-rubbing alcohol in the first week, we randomly assigned them into 1:1 groups (VR training and video lecture groups). The primary outcome was differences in hand-rubbed alcohol use before and after intervention.</div></div><div><h3>Results</h3><div>Before the intervention, alcohol use did not significantly differ between both groups. After the intervention, a significant increase in alcohol use was observed in the VR training group (median: 8.2 g vs 16.2 g; <em>P</em> = .019) but not in the video lecture group.</div></div><div><h3>Conclusions</h3><div>Our immersive 360° VR education system enhanced hand hygiene practices. Infection prevention and control practitioners and digital technology experts must collaborate to advance the development of superior educational devices and content.</div></div>","PeriodicalId":7621,"journal":{"name":"American journal of infection control","volume":"53 1","pages":"Pages 65-69"},"PeriodicalIF":3.8,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141911344","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Response to the letter to the editor regarding “The efficacy of an alcohol-based nasal antiseptic versus mupirocin or an iodophor for preventing SSIs using a meta-analysis” 回复关于“基于酒精的鼻腔杀菌剂与莫匹罗星或碘伏预防ssi的meta分析效果”的致编辑的信。

IF 3.8 3区医学

American journal of infection control Pub Date : 2025-01-01 DOI: 10.1016/j.ajic.2024.09.018

Karen K. Hoffmann MS, BSN, RN , Connie Steed MSN, RN , David Kremelberg PhD, MA , Richard Wenzel MD, MSc

引用次数: 0

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IF 3.8 3区医学

American journal of infection control Pub Date : 2025-01-01 DOI: 10.1016/S0196-6553(24)00867-8

引用次数: 0

COVID-19 vaccine uptake inequality among older adults: A multidimensional demographic analysis COVID-19 老年人疫苗接种率不平等：多维人口分析。

IF 3.8 3区医学

American journal of infection control Pub Date : 2025-01-01 DOI: 10.1016/j.ajic.2024.09.007

Seyed M. Karimi PhD , Md Yasin Ali Parh MS , Shaminul H. Shakib PhD , Hamid Zarei MS , Venetia Aranha MPH , Angela Graham MPH , Trey Allen PhD , Sirajum Munira Khan MS , Mana Moghadami MD , Demetra Antimisiaris PharmD , William Paul McKinney PhD , Bert Little PhD , YuTing Chen MPH, MS , Taylor Ingram MPH

{"title":"COVID-19 vaccine uptake inequality among older adults: A multidimensional demographic analysis","authors":"Seyed M. Karimi PhD , Md Yasin Ali Parh MS , Shaminul H. Shakib PhD , Hamid Zarei MS , Venetia Aranha MPH , Angela Graham MPH , Trey Allen PhD , Sirajum Munira Khan MS , Mana Moghadami MD , Demetra Antimisiaris PharmD , William Paul McKinney PhD , Bert Little PhD , YuTing Chen MPH, MS , Taylor Ingram MPH","doi":"10.1016/j.ajic.2024.09.007","DOIUrl":"10.1016/j.ajic.2024.09.007","url":null,"abstract":"<div><h3>Background</h3><div>Age, race, ethnicity, and sex are important determinants of coronavirus disease of 2019 (COVID-19) outcomes. Older adults (65 years and older) are at the highest risk of COVID-19 morbidity and mortality. Analyzing their vaccine uptake by subclassifying demographics is rare and can assist vaccination policies. This study investigates COVID-19 dose 1 and 2 vaccine uptakes among them by race, ethnicity, and sex.</div></div><div><h3>Methods</h3><div>Immunization registry data were used to calculate temporal changes in older adults’ COVID-19 vaccine uptake by race, ethnicity, race-sex, and ethnicity-sex in Kentucky’s most populous county, Jefferson County, during the first 6 quarters of the COVID-19 vaccination program.</div></div><div><h3>Results</h3><div>By May 2022, the county’s Asian residents had the highest dose 1 and 2 vaccination rates (97.0% and 80.4%), then White residents (90.0% and 80.2%). Black residents had one of the lowest COVID-19 vaccination rates (87.3% and 77.3%). The rate among Hispanic residents (82.0% and 66.4%) was considerably lower than non-Hispanic residents (90.2% and 80.1%). The rates were consistently lower in males.</div></div><div><h3>Conclusions</h3><div>Racial, ethnic, and sex-based COVID-19 vaccine inequalities were largely maintained during the study period. Vaccine rollout practices and promotional programs should aim to boost the uptake of the COVID-19 vaccination among racial minority and male older adults.</div></div>","PeriodicalId":7621,"journal":{"name":"American journal of infection control","volume":"53 1","pages":"Pages 115-125"},"PeriodicalIF":3.8,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142279010","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Assessing COVID-19 transmission risk: Roommate and unit mate exposures at an inpatient behavioral health facility 评估 COVID-19 传播风险：住院行为健康机构中的室友和单位配偶接触。

IF 3.8 3区医学

American journal of infection control Pub Date : 2025-01-01 DOI: 10.1016/j.ajic.2024.09.003

Jennifer Falgione MPH , Graham M. Snyder MD, SM , Catherine Cannon MSN, BSN , Janina-Marie Huss MBA, CIC, LTC-CIP

{"title":"Assessing COVID-19 transmission risk: Roommate and unit mate exposures at an inpatient behavioral health facility","authors":"Jennifer Falgione MPH , Graham M. Snyder MD, SM , Catherine Cannon MSN, BSN , Janina-Marie Huss MBA, CIC, LTC-CIP","doi":"10.1016/j.ajic.2024.09.003","DOIUrl":"10.1016/j.ajic.2024.09.003","url":null,"abstract":"<div><h3>Background</h3><div>Inpatient psychiatric facilities have an increased risk of infection transmission. This study evaluated the impact of roommate and unit mate exposures on coronavirus disease-2019 (COVID-19) transmission to inform isolation practices.</div></div><div><h3>Methods</h3><div>A single-center retrospective study was conducted among patients hospitalized in an inpatient behavioral health hospital from July 2020 through August 2023. We compared the risk of COVID-19 acquisition after exposure among patients with a contagious roommate versus those exposed to a contagious unit mate.</div></div><div><h3>Results</h3><div>During the study period, the conversion rate was 10.05% overall, 24.4% for roommates, and 9.3% for unit mates; patients exposed to a roommate were at 3.14 times higher odds (95% confidence interval, 1.42-6.92) of acquiring COVID-19 after exposure. On unit-stratified analysis, patients exposed to a roommate on the geropsychiatric unit had the highest risk of postexposure conversion compared with unit mate exposed patients (odds ratio 6.38, 95% confidence interval 1.75-23.22). Logistic regression analysis identified a nonsignificant risk associated with increased time in group therapy.</div></div><div><h3>Conclusions</h3><div>Exposure to a COVID-19-contagious roommate significantly increases the risk of COVID-19 acquisition among exposed patients receiving inpatient psychiatric care. Cohorting contagious and exposed individuals and avoiding multibedded rooms may mitigate COVID-19 transmission risk during psychiatric care.</div></div>","PeriodicalId":7621,"journal":{"name":"American journal of infection control","volume":"53 1","pages":"Pages 110-114"},"PeriodicalIF":3.8,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142279096","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Elimination of an outbreak of carbapenem-resistant Acinetobacter baumannii in a burn unit 消除烧伤科爆发的耐碳青霉烯类鲍曼不动杆菌。

IF 3.8 3区医学

American journal of infection control Pub Date : 2025-01-01 DOI: 10.1016/j.ajic.2024.10.002

Nancy L. Havill MT(ASCP), MHA, CIC , Monique Samuels BSN, RN, CIC , Anjali Poudyal RN, MPH, CIC , Vineetha Sujanan RN, MSN, CIC , Christina Murdzek M(ASCP), MHS, CIC , Michael J. Aniskiewicz M(ASCP), CIC , Meghan Maloney MPH, CIC , Jacqueline Laird BSN, RN, CNM , Alisa Savetamal MD, FACS

引用次数: 0

A multilayered infection control intervention on carbapenem-resistant Acinetobacter baumannii acquisition: An interrupted time series 针对耐碳青霉烯类鲍曼不动杆菌感染的多层次感染控制干预：间断时间序列。

IF 3.8 3区医学

American journal of infection control Pub Date : 2025-01-01 DOI: 10.1016/j.ajic.2024.08.018

Daniel Grupel MD , Abraham Borer MD , Riki Yosipovich RN , Ronit Nativ RN, MPH , Orli Sagi PhD , Lisa Saidel-Odes MD

{"title":"A multilayered infection control intervention on carbapenem-resistant Acinetobacter baumannii acquisition: An interrupted time series","authors":"Daniel Grupel MD , Abraham Borer MD , Riki Yosipovich RN , Ronit Nativ RN, MPH , Orli Sagi PhD , Lisa Saidel-Odes MD","doi":"10.1016/j.ajic.2024.08.018","DOIUrl":"10.1016/j.ajic.2024.08.018","url":null,"abstract":"<div><h3>Background</h3><div>Carbapenem-resistant <em>Acinetobacter baumannii</em> (CRAB) causes life-threating hospital-acquired. Due to a limited number of Intensive-Care-Unit (ICU) beds, these patients are often treated in high-dependency (HD) non-ICUs within internal-medicine wards (IMW) in Israel. We aimed to assess the effectiveness of a multilayered infection-control intervention on CRAB infection rate in IMWs, especially in its HD non-ICUs with ongoing CRAB transmission.</div></div><div><h3>Methods</h3><div>A quasi-experimental, before-and-after, interrupted time-series study with control outcomes. We conducted a multilayered intervention over 3.5years, which included 4 phases: (1) Pre intervention; (2) Intervention introduction: introduced enhanced environment cleaning; (3) Intervention phase 1: introduced active surveillance; (4) Intervention phase 2: introduced CRAB-positive patient cohorting, in addition to previous ongoing measures taken.</div></div><div><h3>Results</h3><div>CRAB was isolated from 204 patients aged 69.8y/o ± 15.86y, 59.8% male, 34.3% had CRAB-positive clinical samples. Mean hospital length-of-stay was 30.5days, with a 30-day postdischarge mortality rate of 55.9%. Mean CRAB clinical cases decreased from 0.89 in preintervention to 0.11 at the end of phase 2, with a change in slope and level after the intervention of <em>P</em> = .02 (CI: −0.204 to −0.040) and <em>P</em> = .004 (CI: −0.013 to −0.003), respectively.</div></div><div><h3>Conclusions</h3><div>This intervention, including enhanced environment cleaning, active surveillance, and patient cohorting, successfully reduced CRAB acquisition in IMWs and their HD non-ICUs.</div></div>","PeriodicalId":7621,"journal":{"name":"American journal of infection control","volume":"53 1","pages":"Pages 98-104"},"PeriodicalIF":3.8,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142054665","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Integrating residents’ rights and infection prevention in nursing homes: Summary of the Infection Control Advocate and Resident Education (ICARE) learning modules pilot for long-term care ombudsmen, residents, and other nursing home advocates 将居民权利与养老院感染预防相结合：针对长期护理监察员、居民和其他养老院倡导者的感染控制倡导者和居民教育（ICARE）学习模块试点总结。

IF 3.8 3区医学

American journal of infection control Pub Date : 2025-01-01 DOI: 10.1016/j.ajic.2024.09.013

Diana Cervantes MS, DrPH, CIC, LTC-IP, FAPIC , Brittany Krenek MPH , Sarah Ross DO, MS, CMD , Janice A. Knebl DO, MBA, FACP, MACOI, CPPS

引用次数: 0