American journal of infection control最新文献_第2页

A Burkholderia contaminans outbreak in an intensive care unit associated with contaminated bath solution: Control and microbiological findings. 重症监护室爆发的伯克霍尔德氏菌污染与受污染的浴液有关：控制和微生物学发现。

IF 3.8 3区医学

American journal of infection control Pub Date : 2024-10-22 DOI: 10.1016/j.ajic.2024.10.006

Daniela Kallíope de Sá Paraskevopoulos, Carlos Henrique Camargo, Priscila Koba Kodato, Amanda Yaeko Yamada, Adriana Aparecida Buzzo Almodovar, Ellen Gameiro Hilinski, Alexandre Inácio de Paula, Elaine Fernanda Irineu, Sandra Rodrigues Barrio, Cibele L Fonseca, Cristiano de Melo Gamba, Nair Hosino, Augusto Yamaguti, João S de Mendonça, Thaís Guimarães

{"title":"A Burkholderia contaminans outbreak in an intensive care unit associated with contaminated bath solution: Control and microbiological findings.","authors":"Daniela Kallíope de Sá Paraskevopoulos, Carlos Henrique Camargo, Priscila Koba Kodato, Amanda Yaeko Yamada, Adriana Aparecida Buzzo Almodovar, Ellen Gameiro Hilinski, Alexandre Inácio de Paula, Elaine Fernanda Irineu, Sandra Rodrigues Barrio, Cibele L Fonseca, Cristiano de Melo Gamba, Nair Hosino, Augusto Yamaguti, João S de Mendonça, Thaís Guimarães","doi":"10.1016/j.ajic.2024.10.006","DOIUrl":"10.1016/j.ajic.2024.10.006","url":null,"abstract":"Background: The Burkholderia cepacia complex comprises a group of bacteria with a growing threat as a contaminant of nonsterile solutions. We describe an outbreak of a Burkholderia cepacia complex involving patients at intensive care unit related to a no-rinse bathing solution (NRBS).Methods: We carried out patients, environmental and laboratory investigation performing analyses of cases, pulsed-field-gel electrophoresis and whole genome sequence (WGS) of isolates.Results: We investigated 32 cases and 16 isolates that were identified as Burkholderia contaminans, belonging to 2 different clones. One clone (new ST2175) was identified in 6 sequences (4 from patients and 2 from bath cart samples) and for the remaining 10 isolates (7 isolates from patients and 3 from NRBS) we identified the ST762. The investigation demonstrated that NRBS was the source of the outbreak caused by ST762 clone of B contaminans.Discussion: Early suspicion of a common source, rapid implementation of control measures, and laboratory support are vital in an outbreak investigation. We also highlight the role of WGS which was very important to conclude our investigation regarding environmental samples and bacterial typing.Conclusions: We highlight the need to regulate water-based products and the role of WGS for investigate environmental samples.","PeriodicalId":7621,"journal":{"name":"American journal of infection control","volume":null,"pages":null},"PeriodicalIF":3.8,"publicationDate":"2024-10-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142492962","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Infection Prevention and Control in Long-term Care Facilities in Florida: A Needs Assessment Survey. 佛罗里达州长期护理机构的感染预防与控制：需求评估调查。

IF 3.8 3区医学

American journal of infection control Pub Date : 2024-10-22 DOI: 10.1016/j.ajic.2024.10.008

Cindy Prins, Avery E Bollinger, Cassandra L Johnson, Jamie L Pomeranz, Sally M Bethart, Kartikeya Cherabuddi, Ann L Horgas, Veena Venugopalan, Nicole M Marlow, Duzgun Agdas, Chang-Yu Wu, Antarpreet Singh Jutla, Mishal Khan, Argentina Charles, F Lee Revere

{"title":"Infection Prevention and Control in Long-term Care Facilities in Florida: A Needs Assessment Survey.","authors":"Cindy Prins, Avery E Bollinger, Cassandra L Johnson, Jamie L Pomeranz, Sally M Bethart, Kartikeya Cherabuddi, Ann L Horgas, Veena Venugopalan, Nicole M Marlow, Duzgun Agdas, Chang-Yu Wu, Antarpreet Singh Jutla, Mishal Khan, Argentina Charles, F Lee Revere","doi":"10.1016/j.ajic.2024.10.008","DOIUrl":"https://doi.org/10.1016/j.ajic.2024.10.008","url":null,"abstract":"Background: Although several surveys of infection prevention and control (IPC) practices have been conducted in the United States, none have focused on the state of Florida, which has the fourth largest number of certified nursing facilities in the country. A needs assessment survey was conducted to better understand the specific needs and practices of individuals responsible for IPC in long-term care facilities (LTCFs) in Florida.Methods: In November and December of 2022, a 90-question online survey was distributed to individuals responsible for IPC activities at 3,690 LTCFs in Florida. After omitting incomplete responses, 304 survey responses were analyzed using descriptive statistics.Results: Survey responses regarding hand hygiene, sharps safety, and staff training reflect compliance with recommended IPC practices. Staffing shortages for Registered Nurses, Licensed Practical Nurses, and Certified Nursing Assistants were high among respondents (30%), while few reported shortages of Personal Protective Equipment (5%). Only 11% of respondents state their facility requires flu vaccines despite the high-risk environment of LTCFs. Concerning the built environment, the results suggest Infection Preventionists have limited awareness of the scope of heating, ventilation, and air conditioning systems in their facilities.Conclusion: Some areas of compliance with IPC best practices were noted, but multiple opportunities for education and training on IPC best practices were identified.","PeriodicalId":7621,"journal":{"name":"American journal of infection control","volume":null,"pages":null},"PeriodicalIF":3.8,"publicationDate":"2024-10-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142492964","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

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IF 3.8 3区医学

American journal of infection control Pub Date : 2024-10-19 DOI: 10.1016/S0196-6553(24)00729-6

引用次数: 0

Targeting prolonged short-term central venous catheters to reduce hospital-wide catheter days and CLABSI rates. 针对长期短期中心静脉导管，减少全院导管使用天数和 CLABSI 感染率。

IF 3.8 3区医学

American journal of infection control Pub Date : 2024-10-19 DOI: 10.1016/j.ajic.2024.10.011

Regev Cohen, Shelly Lipman-Arens, Lamis Mahamid, Linor Ishay, Olga Feld Simon, Sharon Reisfeld, Orna Ben-Natan, Aliza Vaknin, Mohammed Ganayem, Razi Abu Hadba, Erez Karisi, Noa Melnik, Sarit Freimann, Maanit Shapira, Nina Avshovich, Ayed Darawshe, Ronit Rachmilevitch, Valery Istomin, Rena Abilevitch, Saif Abu-Mouch, Rotem Novoselsky, Marinella Beckerman, Vlada Dubinchik, Boris Kessel, Veacheslav Zilbermints, Veronika Starobinsky, Inna Furman, Konstantin Neimark, Yaakov Daskal, Mohanad Ganayem, Fanny Biton, Boris Isakovich, Elias Tannous

{"title":"Targeting prolonged short-term central venous catheters to reduce hospital-wide catheter days and CLABSI rates.","authors":"Regev Cohen, Shelly Lipman-Arens, Lamis Mahamid, Linor Ishay, Olga Feld Simon, Sharon Reisfeld, Orna Ben-Natan, Aliza Vaknin, Mohammed Ganayem, Razi Abu Hadba, Erez Karisi, Noa Melnik, Sarit Freimann, Maanit Shapira, Nina Avshovich, Ayed Darawshe, Ronit Rachmilevitch, Valery Istomin, Rena Abilevitch, Saif Abu-Mouch, Rotem Novoselsky, Marinella Beckerman, Vlada Dubinchik, Boris Kessel, Veacheslav Zilbermints, Veronika Starobinsky, Inna Furman, Konstantin Neimark, Yaakov Daskal, Mohanad Ganayem, Fanny Biton, Boris Isakovich, Elias Tannous","doi":"10.1016/j.ajic.2024.10.011","DOIUrl":"10.1016/j.ajic.2024.10.011","url":null,"abstract":"Background: The risk of central line-associated bloodstream infection (CLABSI) is associated with central venous catheter (CVC) dwelling time. We implemented a hospital-wide intervention aimed to alert physicians to CVC duration and necessity and to improve the monitoring of CLABSI prevention process measures outside the intensive care unit (ICU).Methods: A retrospective, before-after study that evaluated short-term, nonhemodialysis CVCs in and out of the ICU. The intervention included enhanced bundle-prevention measures monitoring and staff \"sensitization\" regarding prolonged (> 7 days) CVCs (pCVCs). The ICU intervention also included daily CVC-stewardship visits. We assessed CVC utilizations and CLABSI episodes 20 months before to 19 months after the intervention using Mann-Whitney tests.Results: Out of the ICU, CVC-utilization ratio (CVC-UR) and pCVC-UR reduced significantly (4.1-2.7/100 hospital days, P = .005; and 28%-21%, P = .02, respectively). Bundle-prevention measures improved, and CLABSI rates reduced postintervention (7.9-3.6/1,000 CVC days, P = .03). In the ICU, pCVC-UR reduced significantly (29%-15%, P < .0001). Baseline ICU-CLABSI rates were low and did not reduce postintervention.Conclusions: Sensitizing physicians to the existence and duration of CVCs accompanied by improved bundle-prevention measures, resulted in reduction of pCVCs, and outside the ICU, also in reduction of CVC-UR and CLABSI rates.","PeriodicalId":7621,"journal":{"name":"American journal of infection control","volume":null,"pages":null},"PeriodicalIF":3.8,"publicationDate":"2024-10-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142455937","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

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IF 3.8 3区医学

American journal of infection control Pub Date : 2024-10-19 DOI: 10.1016/S0196-6553(24)00728-4

引用次数: 0

Persistent carbapenem resistance in mechanically ventilated ICU patients: A before-and-after analysis of the COVID-19 surge. 机械通气 ICU 患者对碳青霉烯耐药性的持续存在：COVID-19 浪潮前后的分析。

IF 3.8 3区医学

American journal of infection control Pub Date : 2024-10-19 DOI: 10.1016/j.ajic.2024.10.014

Bianca B P Antunes, Leonardo S L Bastos, Pedro Kurtz, Letícia M Sant'Anna, Pedro F Del Peloso, Claudia A Espanha, Silvio Hamacher, Fernando A Bozza

{"title":"Persistent carbapenem resistance in mechanically ventilated ICU patients: A before-and-after analysis of the COVID-19 surge.","authors":"Bianca B P Antunes, Leonardo S L Bastos, Pedro Kurtz, Letícia M Sant'Anna, Pedro F Del Peloso, Claudia A Espanha, Silvio Hamacher, Fernando A Bozza","doi":"10.1016/j.ajic.2024.10.014","DOIUrl":"https://doi.org/10.1016/j.ajic.2024.10.014","url":null,"abstract":"Objective: How did the antimicrobial resistance profile of critically ill patients evolve before, during, and after COVID-19 surge periods?Methods: We retrospectively analysed all critically ill mechanically ventilated adult patients admitted to eight Brazilian hospitals from January 1st, 2018, to April 30th, 2023. We stratified the patients into three periods based on their admission date: pre-surge (Jan 01/2018-Mar 01/2020), surge (Mar 01/2020 - Oct 01/2021), and post-surge (after Oct 01/2021). We compared the proportion of positive cultures, prevalence of pathogens, and resistance rates across periods using the rate ratios (RR) and their 95% confidence intervals (95% CI).Results: We analysed 9,780 ICU patients: 3,718 were in the pre-surge, 3,815 in the surge, and 2,247 in the post-surge period. Patients in the surge period were younger (median: 70 vs. 74 pre-surge vs. 75 post-surge) and presented a higher duration of invasive mechanical ventilation (median 7 vs. 5 days). The utilisation of blood and respiratory cultures increased throughout periods (56.9 pre-surge vs. 69.4 surge vs. 70.4 patients/1,000 patient days post-surge). The isolation of carbapenem-resistant gram-negative bacteria increased during the surge (RR [95% CI]: 1.8 [1.5-2.2], compared to pre-surge), decreased in post-surge (RR [95% CI]: 0.72 [0.6-0.9], and remained higher than pre-surge (RR [95% CI]: 1.3 [1.0-1.6]). Resistance rates for Pseudomonas aeruginosa reduced from 32% in pre- to 23% post-surge, whereas Klebsiella pneumoniae doubled during the surge, 26% to 52%, and remained higher than pre-surge.Conclusion: Carbapenem resistance increased during the surge period. Although it decreased post-surge, it remained higher than the rates observed before the pandemic.","PeriodicalId":7621,"journal":{"name":"American journal of infection control","volume":null,"pages":null},"PeriodicalIF":3.8,"publicationDate":"2024-10-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142455936","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

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IF 3.8 3区医学

American journal of infection control Pub Date : 2024-10-19 DOI: 10.1016/S0196-6553(24)00727-2

引用次数: 0

Facility-Level Antibiotic Prescribing Rates and the Use of Antibiotics Among Nursing Home Residents. 养老院居民的抗生素处方率和抗生素使用情况。

IF 3.8 3区医学

American journal of infection control Pub Date : 2024-10-18 DOI: 10.1016/j.ajic.2024.10.007

Quynh T Vo, Farzad Noubary, Brandon Dionne, Shira Doron, Benjamin Koethe, Becky A Briesacher

{"title":"Facility-Level Antibiotic Prescribing Rates and the Use of Antibiotics Among Nursing Home Residents.","authors":"Quynh T Vo, Farzad Noubary, Brandon Dionne, Shira Doron, Benjamin Koethe, Becky A Briesacher","doi":"10.1016/j.ajic.2024.10.007","DOIUrl":"https://doi.org/10.1016/j.ajic.2024.10.007","url":null,"abstract":"Background: The high frequency of antibiotic use in U.S. nursing homes is a public health concern and target of antimicrobial stewardship efforts. Facility-level prescribing patterns may provide a measure for antibiotic stewardship targeting.Methods: An analysis of 2018 and 2019 data from four linked files from the Centers for Medicaid and Medicare was conducted. Multilevel generalized linear models were used to calculate odds ratios for antibiotic receipt for calendar year 2019 using the 2018 facility prescribing rate, controlling for facility and individual-level factors.Results: In 2019, 186,274 (19%) study residents were prescribed an antibiotic. The most frequently prescribed class of antibiotics were cephalosporins (26%) and the average duration of antibiotic use was 9 days. Residents who were dually eligible for Medicare and Medicaid had 37% increased odds of antibiotic receipt (All aOR: 1.37, 95%CI: 1.35,1.39). The 2018 facility prescribing rate was associated with 14% increased odds of antibiotic receipt in 2019 in nursing homes in the medium (11.9-20.2%) prescribing category (All aOR: 1.14, 95%CI: 1.11,1.17) and 36% increased odds of antibiotic receipt in nursing homes in the high (>20.3%) prescribing category (All aOR: 1.36, 95%CI: 1.32,1.40) when compared to the lowest (0-11.8%) prescribing category.Conclusions: Antibiotic stewardship strategies should target nursing homes with high antibiotic prescribing rates and high populations of dually eligible patients to improve care in this population.","PeriodicalId":7621,"journal":{"name":"American journal of infection control","volume":null,"pages":null},"PeriodicalIF":3.8,"publicationDate":"2024-10-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142455933","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Comparative analysis of hospital-acquired and community-acquired infections at a tertiary hospital in China before and during COVID-19: A 7-year longitudinal study (2017-2023). COVID-19之前和期间中国一家三甲医院医院获得性感染和社区获得性感染的对比分析：为期7年的纵向研究（2017-2023年）。

IF 3.8 3区医学

American journal of infection control Pub Date : 2024-10-18 DOI: 10.1016/j.ajic.2024.10.009

Xiang Su, Jianing Niu, Fang Wang, Ling Sun

{"title":"Comparative analysis of hospital-acquired and community-acquired infections at a tertiary hospital in China before and during COVID-19: A 7-year longitudinal study (2017-2023).","authors":"Xiang Su, Jianing Niu, Fang Wang, Ling Sun","doi":"10.1016/j.ajic.2024.10.009","DOIUrl":"10.1016/j.ajic.2024.10.009","url":null,"abstract":"Background: This 7-year longitudinal survey (2017-2023) assessed the point prevalence of hospital-acquired infections (HAIs) and community-acquired infections (CAIs) at a first-class tertiary hospital in China, both prior to and during the Corona Virus Disease 2019 (COVID-19) pandemic.Methods: Patients were stratified into prepandemic and pandemic periods, as well as into stringent and relaxed infection prevention and control (IPC) phases, to compare the point prevalence of HAIs and CAIs.Results: The overall point prevalence of HAIs was 1.50% (95% confidence interval [CI], 1.32%-1.71%), showing a significant downward trend (P = .021). Among patients receiving pathogen testing, the point prevalence of HAIs significantly declined during the pandemic (6.26% vs 9.89%, P < .001). The point prevalence of CAIs demonstrated a notable increase in 2023 compared with 2020 to 2022 among pathogen-tested patients (81.37% vs 74.18%, P = .001). Multivariate analysis identified hospitalization during the pandemic as a protective factor against HAIs (adjusted odds ratio 0.49, 95% CI, 0.36-0.67).Conclusions: The comprehensive IPC strategy implemented during the COVID-19 pandemic at this tertiary hospital significantly reduced the point prevalence of HAIs. However, CAIs exhibited a rising trend following the relaxation of COVID-19 IPC measures.","PeriodicalId":7621,"journal":{"name":"American journal of infection control","volume":null,"pages":null},"PeriodicalIF":3.8,"publicationDate":"2024-10-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142456030","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The patterns of antifungal use and risk factors associated with mortality in patients with invasive candidiasis and aspergillosis infections among patients who were received infectious disease specialist consultation prior to and during the COVID-19 pandemic in a resource-limited setting: A retrospective cohort study. 在资源有限的环境中，COVID-19 大流行之前和期间接受传染病专家会诊的侵袭性念珠菌病和曲霉菌病患者的抗真菌药物使用模式以及与死亡率相关的风险因素：一项回顾性队列研究。

IF 3.8 3区医学

American journal of infection control Pub Date : 2024-10-18 DOI: 10.1016/j.ajic.2024.10.013

Supavit Vaivoothpinyo, Kittiya Jantarathaneewat, David J Weber, Bernard C Camins, Piyaporn Apisarnthanarak, Sasinuch Rutjanawech, Anucha Apisarnthanarak

{"title":"The patterns of antifungal use and risk factors associated with mortality in patients with invasive candidiasis and aspergillosis infections among patients who were received infectious disease specialist consultation prior to and during the COVID-19 pandemic in a resource-limited setting: A retrospective cohort study.","authors":"Supavit Vaivoothpinyo, Kittiya Jantarathaneewat, David J Weber, Bernard C Camins, Piyaporn Apisarnthanarak, Sasinuch Rutjanawech, Anucha Apisarnthanarak","doi":"10.1016/j.ajic.2024.10.013","DOIUrl":"10.1016/j.ajic.2024.10.013","url":null,"abstract":"Background: Limited data is available concerning the patterns of antifungal use and Invasive fungal infection (IFI)-associated mortality risk factors in patients with IFI prior to and during the Coronavirus disease 2019 (COVID-19) pandemic in resource-limited settings.Methods: A single-center retrospective cohort study was conducted. All patients age >18 years diagnosed with IFIs were prospectively followed during a 3-year pre-COVID-19 pandemic period and a 3-year during COVID-19 pandemic period. Patient characteristics, the patterns of antifungal use, IFI-associated mortality risk factors, and adverse drug events were collected.Results: There was a total of 133 patients in this study: 60 (45.1%) were in period 1 and 73 (54.9%) were in period 2. Pre-emptive antifungal therapy was commonly practiced in period 2 (21.7% vs 37%, P = .05). The presence of a central venous catheter (aOR 3.19, P = .007), hematologic adverse drug events (aOR 17.9, P = .008) were preventable risks for the overall IFI mortality in both periods. Appropriate antifungal use was protective against the overall IFI mortality in period 2 (aOR 0.09, P = .009).Conclusions: Several preventable risk factors associated with mortality were identified and served as a key for improvement of infection prevention, national policy to access antifungal agents, and antifungal stewardship in resource-limited settings.","PeriodicalId":7621,"journal":{"name":"American journal of infection control","volume":null,"pages":null},"PeriodicalIF":3.8,"publicationDate":"2024-10-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142455938","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0