American journal of infection control最新文献

{"title":"The CONSIDER study: assessing the risk of catheter-associated bloodstream infections beyond the intensive care setting.","authors":"Fabio Borgonovo, Marta Colaneri, Federico Fassio, Giovanni Scaglione, Lucia Galli, Martina Offer, Camilla Genovese, Rebecca Fattore, Monica Schiavini, Giovanni De Capitani, Maria Calloni, Arianna Bartoli, Francesco Casella, Alba Taino, Antonio Gidaro, Chiara Cogliati, Valentina Breschi, Jessica Leoni, Andrea Gori, Antonella Foschi","doi":"10.1016/j.ajic.2025.05.020","DOIUrl":"https://doi.org/10.1016/j.ajic.2025.05.020","url":null,"abstract":"<p><strong>Background: </strong>Catheter-associated and related bloodstream infection (CABSI and CRBSI) are major causes of hospital- acquired infections. However, their incidence and risk factors in non-ICU patients with vascular access devices (VADs) are scarce.</p><p><strong>Methods: </strong>This retrospective study conducted at a large university Hospital of Northern Italy (2021-2024) evaluated CABSI and CRBSI incidence and risk factors in non-ICU hospitalized adults with VADs. Hazard ratios (HR) were estimated with gamma frailty models and random survival forest analysis with sensitivity tests. Key variables were identified and validated in multivariable models.</p><p><strong>Results: </strong>Among 2,326 VAD insertions (corresponding to 1,892 patients), 153 with CRBSI or CABSI were identified. The incidence was 1.80 per 1,000 catheter-days for CABSI, 1.24 per 1,000 catheter-days for CRBSI, and the overall incidence of around 2.97 per 1,000 catheter-days. Coagulase-negative staphylococci were the most isolated pathogens (43.9%). Infections were associated to factors such as parenteral nutrition (PN) (HR = 4.12) and multi-lumen catheters (HR = 2.56). Random Survival Forest models identified PN, intravenous drug use (IVDU), and in-patient regimen as top variables. Specifically, CRBSI showed stronger associations with PN (HR = 7.42), while CABSI was linked to IVDU (HR = 7.20).</p><p><strong>Conclusion: </strong>Our study showed a significantly high incidence of CABSI and CRBSI in non-ICU adult patients. By identifying the risk factors of these infections, it suggests the settings in which stringent infection prevention strategies are needed.</p>","PeriodicalId":7621,"journal":{"name":"American journal of infection control","volume":" ","pages":""},"PeriodicalIF":3.8,"publicationDate":"2025-06-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144245794","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Interventions to prevent bloodstream infections associated with central venous access devices: priorities for an adaptive platform trial.","authors":"Claire M Rickard, Andrew J Stewardson, Sally M Havers, Niccolo Buetti, Kevan R Polkinghorne, Aleece MacPhail, Zoe McQuilten, Benjamin Lazarus, Karina R Charles, Jessica A Schults","doi":"10.1016/j.ajic.2025.06.003","DOIUrl":"https://doi.org/10.1016/j.ajic.2025.06.003","url":null,"abstract":"<p><p>Healthcare-associated bloodstream infections are serious complications of central venous access devices (CVADs). Numerous preventative interventions exist, but without high-level evidence. The IVCare adaptive platform trial will provide multiple answers for infection prevention. A prioritization study with infection preventionists using the SHEA CLABSI prevention framework identified priorities for IVCare intervention testing as: vascular access teams, education/competency for CVAD insertion/post-insertion care, sutureless securement, connector type and decontamination method.</p>","PeriodicalId":7621,"journal":{"name":"American journal of infection control","volume":" ","pages":""},"PeriodicalIF":3.8,"publicationDate":"2025-06-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144245792","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Environmental Detection and Genetic Profiling of Acanthamoeba in High-Risk Medical Facilities.","authors":"Sara Sareminejad, Farnaz Kheirandish, Amirreza Javadi Mamaghani, Maryam Niyyati, Farzad Ebrahimzadeh, Mohammad Yarahmadi, Azadeh Karimi, Syedeh Fatemeh Moosavi, Nozhat Zebardast, Shirzad Fallahi","doi":"10.1016/j.ajic.2025.05.022","DOIUrl":"https://doi.org/10.1016/j.ajic.2025.05.022","url":null,"abstract":"<p><strong>Background: </strong>Acanthamoeba is one of the most common environmental protozoans with a global distribution. Acanthamoeba parasites can be isolated from contact lenses, cleaning solutions, ventilation systems, dental treatment units, dialysis units, and emergency showers. Since the genus Acanthamoeba can lead to dangerous infectious diseases in immunocompromised patients, monitoring medical centers and hospitals admitting these patients, who are more susceptible to these infections, is of great importance. This study aimed to isolate, analyze, and characterize Acanthamoeba strains obtained from high-risk medical centers in Khorramabad city, western Iran, using parasitological (culture and microscopic examination) and molecular (LAMP, PCR, and sequencing) methods.</p><p><strong>Methods: </strong>In this study, 53 dust samples were collected from four high-risk healthcare facilities in Khorramabad City, Western Iran. After being transferred to the laboratory, the samples were cultured in a non-nutritive agar culture medium, and samples with positive cultures were selected for molecular analysis. PCR and LAMP molecular methods targeting 18srRNA gene-specific primers were used to analyze the samples. For molecular confirmation and determination of Acanthamoeba genotypes, 4 randomly selected samples of PCR products were sequenced. The data was analyzed by SPSS-21 software.</p><p><strong>Results: </strong>The culture and microscopic examination showed that 31 out of 53 samples (58.5%) collected from high-risk healthcare facilities were positive for the Acanthamoeba parasite. All the positive samples by the culture method were also positive in the PCR assay. Out of 53 examined samples, 26 were positive by the LAMP technique regarding the presence of the Acanthamoeba parasite. Sequencing results of 4 sequenced samples showed T4 genotypes, Acanthamoeba sp., and Acanthamoeba culbertsoni.</p><p><strong>Conclusions: </strong>The present study showed that the environment of high-risk healthcare facilities in Khorramabad city is contaminated with Acanthamoeba, and the pathogenic T4 genotype is present among the positive samples. Given the severe health implications of Acanthamoeba infections, educating immunocompromised patients about transmission routes and effective preventive measures is crucial. This would help raise awareness and promote safety protocols in healthcare facilities to avoid contamination.</p>","PeriodicalId":7621,"journal":{"name":"American journal of infection control","volume":" ","pages":""},"PeriodicalIF":3.8,"publicationDate":"2025-06-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144245791","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Development of the SMART Toolkit: An Online Collection of Management Resources for Healthcare-Associated Infection Prevention.","authors":"Laura J Rush, Sarah R MacEwan, Courtney Hebert, Lindsey N Sova, Alice A Gaughan, Tyler Griesenbrock, Timothy R Huerta, Ann Scheck McAlearney","doi":"10.1016/j.ajic.2025.06.001","DOIUrl":"https://doi.org/10.1016/j.ajic.2025.06.001","url":null,"abstract":"<p><p>We previously reported results of an in-depth study of management practices to prevent healthcare-associated infections. Here we describe the development of an online toolkit containing resources that can be used to implement six of these key management practices. Resources include practical examples, quotations describing the importance of the practice, facilitator guides and presentation slides for conducting informational sessions, assessment tools, communication templates, and simulation activities. This paper describes the development of the online toolkit, which is available at https://smart.osu.edu/.</p>","PeriodicalId":7621,"journal":{"name":"American journal of infection control","volume":" ","pages":""},"PeriodicalIF":3.8,"publicationDate":"2025-06-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144245790","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A priority framework for the development of a healthcare-associated infection surveillance program in Australian residential aged care homes: analysis of a Delphi technique.","authors":"Eliza Watson, Leon J Worth, Karin Thursky, Lyn-Li Lim, Ann Bull, Janet K Sluggett, David Dunt, Noleen Bennett","doi":"10.1016/j.ajic.2025.05.019","DOIUrl":"https://doi.org/10.1016/j.ajic.2025.05.019","url":null,"abstract":"<p><strong>Background: </strong>There is no agreed scope for a comprehensive national residential aged care home (RACH) healthcare- associated infection (HAI) surveillance program in Australia.</p><p><strong>Methods: </strong>Three sequential surveys were anonymously and independently completed by 25-40 invited subject experts. Each participant, using Likert scales, rated the importance and feasibility of including potential program elements in a national RACH HAI surveillance program. Aggregate agreement levels were defined consensual (>90%, surveys 2 and 3), high (>75%, survey 1 or 75-89%, surveys 2 and 3), moderate (31-74%, all surveys) or low (<30%, all surveys). Program elements were classified 'priority 1' (if there was consensual agreement for importance and feasibility), 2, 3 or non-priority.</p><p><strong>Results: </strong>Of 58 potential program elements, 26 were classified as priority 1; this included program elements focused on infection surveillance (5), infection detection criteria (1), organism surveillance (8), isolate monitoring methods (1), vaccination compliance (4), vaccination compliance targets (4) and antimicrobial appropriateness measures (3). Six, 14 and 12 program elements were classified priority 2,3 and non-priority respectively.</p><p><strong>Conclusion: </strong>Our study developed a strategic framework for a national RACH HAI surveillance program by determining priorities for inclusion of program elements. This framework will be used to develop a pilot program for Australian RACHs.</p>","PeriodicalId":7621,"journal":{"name":"American journal of infection control","volume":" ","pages":""},"PeriodicalIF":3.8,"publicationDate":"2025-06-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144232983","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Investigation of Strongyloides stercoralis in an Intermediate Care Facility for Developmentally Disabled Individuals, New York, Nov. - Dec. 2023.","authors":"Kelly A Barrett, Rowena Clavines, Haillie Meek, Wallace Jenkins, Monica Quinn, Ada Huang, Bruce Reidenberg, Karyn Hirsch, Emily Lutterloh, Geetika Sood","doi":"10.1016/j.ajic.2025.05.021","DOIUrl":"https://doi.org/10.1016/j.ajic.2025.05.021","url":null,"abstract":"<p><strong>Background: </strong>Strongyloidiasis is a parasitic infection caused by the nematode Strongyloides stercoralis and can often be asymptomatic.</p><p><strong>Methods: </strong>An investigation was initiated by the local health department following notification of 3 cases of Strongyloides in a facility for individuals with developmental disabilities in November 2023. Residents and staff were tested using IgG antibody by a commercial laboratory. A site visit was conducted, and staff were interviewed.</p><p><strong>Results: </strong>Among 62 residents and 140 staff tested, 11 (17.7%) residents and 6 (4.3%) staff were positive for Strongyloides IgG antibodies. Age ranged from 29 to 68 years. Most affected residents were male (72%) and located on the 3^rd floor (82%) (odds ratio 2.88 (CI 0.49,30.23)). Almost all residents were incontinent and non-ambulatory. Infection control practices were assessed; a compliance rate of 4% was observed for staff hand hygiene opportunities and 14% for environmental cleaning in resident rooms. Positive cases were treated, and the last case was reported in December 2023.</p><p><strong>Discussion: </strong>This was a large outbreak of strongyloidiasis in a long-term care setting in which transmission was likely attributable to workers and/or environmental contamination.</p><p><strong>Conclusions: </strong>The source of Strongyloides remains unknown; however, adherence to appropriate infection control practices may help to mitigate future outbreaks.</p>","PeriodicalId":7621,"journal":{"name":"American journal of infection control","volume":" ","pages":""},"PeriodicalIF":3.8,"publicationDate":"2025-06-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144232984","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"NSQIP and NHSN: A Tale of Two Definitions","authors":"Margaret M. Gilman MAS, CIC, FAPIC,&nbsp;Kathleen Kiesel MHA, MJ, BSN, RN, CPHRM","doi":"10.1016/j.ajic.2025.03.102","DOIUrl":"10.1016/j.ajic.2025.03.102","url":null,"abstract":"","PeriodicalId":7621,"journal":{"name":"American journal of infection control","volume":"53 6","pages":"Page S38"},"PeriodicalIF":3.8,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144184297","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Protocol Modifications Significantly Reduce Blood Culture Contamination Rates in a High-Acuity Hospital","authors":"Naoko Suzuki,&nbsp;Takashi Akiyama MD, PhD,&nbsp;Takashi Miyazaki,&nbsp;Keita Hasegawa","doi":"10.1016/j.ajic.2025.03.103","DOIUrl":"10.1016/j.ajic.2025.03.103","url":null,"abstract":"","PeriodicalId":7621,"journal":{"name":"American journal of infection control","volume":"53 6","pages":"Page S38"},"PeriodicalIF":3.8,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144184298","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Ultraviolet Light Disinfection: Lack of Impact to Clostridioides difficile at a Community Teaching Hospital","authors":"Ashleigh J. Goris RN, BSN, MPH, CIC, FAPIC ,&nbsp;Kathleen McMullen MPH CIC FAPIC FSHEA ,&nbsp;Sandy L. Jastal BSN, RN, CIC ,&nbsp;Julie Warner BSN, RN, CIC ,&nbsp;Alastair Haddow MD","doi":"10.1016/j.ajic.2025.03.065","DOIUrl":"10.1016/j.ajic.2025.03.065","url":null,"abstract":"","PeriodicalId":7621,"journal":{"name":"American journal of infection control","volume":"53 6","pages":"Pages S22-S23"},"PeriodicalIF":3.8,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144184307","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Using a Risk Assessment to Transition to a 14-day Endoscope Hangtime","authors":"Margaret M. Gilman MAS, CIC, FAPIC,&nbsp;Kwame A. Gyabaah MHA, BS, CHL, CIS, CER, CRCST,&nbsp;Katlyn Burr MSM-HCA, RRT, RRT-NPS, AE-C, FAARC,&nbsp;Edna Gilliam DNP, MBA, RN, CNOR, NEA-BC","doi":"10.1016/j.ajic.2025.03.066","DOIUrl":"10.1016/j.ajic.2025.03.066","url":null,"abstract":"","PeriodicalId":7621,"journal":{"name":"American journal of infection control","volume":"53 6","pages":"Page S23"},"PeriodicalIF":3.8,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144184308","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}