{"title":"Closing the gap on infection prevention staffing recommendations: Results from the beta version of the APIC staffing calculator.","authors":"Rebecca Bartles, Sara Reese, Alexandr Gumbar","doi":"10.1016/j.ajic.2024.09.004","DOIUrl":"10.1016/j.ajic.2024.09.004","url":null,"abstract":"<p><strong>Background: </strong>Published literature suggests \"one-size-fits-all\" infection prevention and control (IPC) staffing recommendations do not sufficiently account for program complexity needs. This project's objective was to create and validate a calculator utilizing risk and complexity factors to generate individualized IPC staffing ratios.</p><p><strong>Methods: </strong>An online survey-based calculator was created that incorporated factors intended to predict staffing needs and multiple investigative questions to allow for optimization of factors in the algorithm. Hospital characteristics, staffing ratios, staffing perception, and outcomes were analyzed to determine the optimal questions and benchmarks for future releases.</p><p><strong>Results: </strong>The median infection preventionist full-time equivalent to bed ratio was 121.0 beds for 390 participating hospitals. The calculator deemed 79.2% of respondent staffing as below expected. Significant association existed between higher standard infection ratio ranges and staffing status for central line-associated bloodstream infection (P = .02), catheter-associated urinary tract infections (P = .001), Clostridioides difficile infections (P = .003), and colon surgical site infections (P = .0001).</p><p><strong>Conclusions: </strong>This novel approach allows facilities to staff their IPC program based on individual factors. Future versions of the calculator will be optimized based on the findings. Future research will clarify the impact of staffing on patient outcomes and staff retention.</p>","PeriodicalId":7621,"journal":{"name":"American journal of infection control","volume":" ","pages":"1345-1350"},"PeriodicalIF":4.3,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142456029","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Rajendra Gyawali, Sarah Gamboa, Kathleen Rolfe, Johanna I Westbrook, Magdalena Z Raban
{"title":"Consumer perspectives on antibiotic use in residential aged care: A mixed-methods systematic review.","authors":"Rajendra Gyawali, Sarah Gamboa, Kathleen Rolfe, Johanna I Westbrook, Magdalena Z Raban","doi":"10.1016/j.ajic.2024.07.008","DOIUrl":"10.1016/j.ajic.2024.07.008","url":null,"abstract":"<p><strong>Background: </strong>Aged care staff and doctors frequently highlight consumers' role in antibiotic treatment decisions. However, few studies include consumers. This study aimed to investigate consumer perspectives on antibiotic use in residential aged care.</p><p><strong>Methods: </strong>A search across 6 online databases yielded 3,373 studies, with 5 meeting inclusion criteria. Participant quotes, themes, statistical analyses, and authors' interpretive summaries in the included studies were inductively coded and refined to generate themes.</p><p><strong>Results: </strong>Three themes emerged: perception of benefits and risks of antibiotics, perceived role in antibiotic treatment decision-making, and information-communication needs. Consumers held positive attitudes toward antibiotics, did not associate antibiotics with the exclusive treatment of bacterial infections, and had limited awareness of potential risks, such as antibiotic resistance. Studies showed diverse perceptions regarding residents' and their families' involvement in antibiotic treatment decision-making with some residents actively seeking antibiotics and others trusting doctors to decide. Studies also described consumer need for effective provider-consumer communication and information sharing that was affected by contextual barriers such as motivation, preferences, available information resources, and provider attitudes.</p><p><strong>Conclusions: </strong>Limited literature is available on consumer perspectives on antibiotic use in aged care. The review highlights that consumer needs are more complex than simply wanting an antibiotic. Antimicrobial stewardship programs should target consumer awareness, beliefs, and provider-consumer communication to enhance antibiotic use in aged care.</p>","PeriodicalId":7621,"journal":{"name":"American journal of infection control","volume":" ","pages":"1452-1459"},"PeriodicalIF":4.3,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141787020","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Vamsi Yengudhati, Jennifer Gutowski, Shannon Glassman, Matthew Phillips, Stephany Frey, Melissa Bronstein, Maryrose Laguio-Vila, Emil Lesho
{"title":"The differential burden of 3 health care-associated infections on hospital costs and lengths of stay: A quasi-experimental case-control observation.","authors":"Vamsi Yengudhati, Jennifer Gutowski, Shannon Glassman, Matthew Phillips, Stephany Frey, Melissa Bronstein, Maryrose Laguio-Vila, Emil Lesho","doi":"10.1016/j.ajic.2024.07.014","DOIUrl":"10.1016/j.ajic.2024.07.014","url":null,"abstract":"<p><p>In patients with a health care-associated infection (HAI), lengths of stay and costs increased >150% from 2019 to 2023, and were 2 to 6 times greater compared to concurrent non-HAI patients with the same diagnoses. Unlike surgical HAI, no device-associated HAI occurred before hospital day 12. These findings highlight the possibly under-recognized influence of delayed discharges on device-associated HAIs.</p>","PeriodicalId":7621,"journal":{"name":"American journal of infection control","volume":" ","pages":"1466-1468"},"PeriodicalIF":4.3,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141858779","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jiaying Li, Guifang Li, Ziqing Liu, Xingyu Yang, Qiuyan Yang
{"title":"Prediction models for the risk of ventilator-associated pneumonia in patients on mechanical ventilation: A systematic review and meta-analysis.","authors":"Jiaying Li, Guifang Li, Ziqing Liu, Xingyu Yang, Qiuyan Yang","doi":"10.1016/j.ajic.2024.07.006","DOIUrl":"10.1016/j.ajic.2024.07.006","url":null,"abstract":"<p><strong>Background: </strong>Identifying patients at risk of ventilator-associated pneumonia through prediction models can facilitate medical decision-making. Our objective was to evaluate the current models for ventilator-associated pneumonia in patients with mechanical ventilation.</p><p><strong>Methods: </strong>Nine databases systematically retrieved from establishment to March 6, 2024. Two independent reviewers performed study selection, data extraction, and quality assessment, respectively. The Prediction Model Risk of Bias Assessment Tool was used to evaluate the risk of model bias and applicability. Stata 17.0 was used to conduct a meta-analysis of discrimination of model validation.</p><p><strong>Results: </strong>The total of 34 studies were included, with reported 52 prediction models. The most frequent predictors in the models were mechanical ventilation duration, length of intensive care unit stay, and age. Each study was essentially considered having a high risk of bias. A meta-analysis of 17 studies containing 33 models with validation was performed with a pooled area under the receiver-operating curve of 0.80 (95% confidence interval: 0.78-0.83).</p><p><strong>Conclusions: </strong>Despite the relatively excellent performance of the models, there is a high risk of bias of the model development process. Enhancing the methodological quality, especially the external validation, practical application, and optimization of the models need urgent attention.</p>","PeriodicalId":7621,"journal":{"name":"American journal of infection control","volume":" ","pages":"1438-1451"},"PeriodicalIF":4.3,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141722869","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Bloodstream infection: Derivation and validation of a reliable and multidimensional prognostic score based on a machine learning model (BLISCO).","authors":"Marta Camici, Benedetta Gottardelli, Tommaso Novellino, Carlotta Masciocchi, Silvia Lamonica, Rita Murri","doi":"10.1016/j.ajic.2024.07.011","DOIUrl":"10.1016/j.ajic.2024.07.011","url":null,"abstract":"<p><strong>Background: </strong>A bloodstream infection (BSI) prognostic score applicable at the time of blood culture collection is missing.</p><p><strong>Methods: </strong>In total, 4,327 patients with BSIs were included, divided into a derivation (80%) and a validation dataset (20%). Forty-two variables among host-related, demographic, epidemiological, clinical, and laboratory extracted from the electronic health records were analyzed. Logistic regression was chosen for predictive scoring.</p><p><strong>Results: </strong>The 14-day mortality model included age, body temperature, blood urea nitrogen, respiratory insufficiency, platelet count, high-sensitive C-reactive protein, and consciousness status: a score of ≥ 6 was correlated to a 14-day mortality rate of 15% with a sensitivity of 0.742, a specificity of 0.727, and an area under the curve of 0.783. The 30-day mortality model further included cardiovascular diseases: a score of ≥ 6 predicting 30-day mortality rate of 15% with a sensitivity of 0.691, a specificity of 0.699, and an area under the curve of 0.697.</p><p><strong>Conclusions: </strong>A quick mortality score could represent a valid support for prognosis assessment and resources prioritizing for patients with BSIs not admitted in the intensive care unit.</p>","PeriodicalId":7621,"journal":{"name":"American journal of infection control","volume":" ","pages":"1377-1383"},"PeriodicalIF":4.3,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141787019","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Kelly Poch, Alexandra Trannel, Nicole Wiltfang, Elizabeth Krigbaum, Oluchi Abosi, Takaaki Kobayashi, Karen Brust
{"title":"Impact of introducing external urinary devices on reducing indwelling urinary catheter days: A quality improvement initiative at a midwestern academic medical center.","authors":"Kelly Poch, Alexandra Trannel, Nicole Wiltfang, Elizabeth Krigbaum, Oluchi Abosi, Takaaki Kobayashi, Karen Brust","doi":"10.1016/j.ajic.2024.08.023","DOIUrl":"10.1016/j.ajic.2024.08.023","url":null,"abstract":"<p><p>External urinary device (EUD) use and modification of the electronic medical record system with defaulting EUD for selected indications significantly decreased the utilization of indwelling urinary catheters while there was no observed significant reduction in catheter-associated urinary tract infections. The introduction of EUD alone may not decrease catheter-associated urinary tract infections and a comprehensive approach involving various strategies from different perspectives will be necessary, particularly diagnostic stewardship.</p>","PeriodicalId":7621,"journal":{"name":"American journal of infection control","volume":" ","pages":"1469-1471"},"PeriodicalIF":4.3,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142131617","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Lori D Moore, James W Arbogast, Greg Robbins, Megan DiGiorgio, Albert E Parker
{"title":"Drastic hourly changes in hand hygiene workload and performance rates: A multicenter time series analysis.","authors":"Lori D Moore, James W Arbogast, Greg Robbins, Megan DiGiorgio, Albert E Parker","doi":"10.1016/j.ajic.2024.08.026","DOIUrl":"10.1016/j.ajic.2024.08.026","url":null,"abstract":"<p><strong>Background: </strong>High hand hygiene (HH) workload is a commonly cited barrier to optimal HH performance. The objective of this study was to assess trends of HH workload as defined by HH opportunities (HHO) and performance rates over different timescales using automated HH monitoring system data.</p><p><strong>Methods: </strong>This multiyear retrospective observational study was conducted in 58 inpatient units located in 10 North American hospitals. HHO and HH rates were analyzed by time series mixed effects general additive model.</p><p><strong>Results: </strong>Median HH rates peaked at 50.0 between 6 and 7 AM with a trough of 38.2 at 5 PM. HHO over hours in a day were the highest at 184 per hospital unit per hour at 10 AM with a trough of 49.0 between 2 and 3 AM. Median rates for day and night shifts were 40.8 and 45.5, respectively (P = .078). Weekend day shift had the lowest median rate (39.4) compared with any other 12-hour shift (P < .1018). The median rates and HHO varied little across days in a week and months.</p><p><strong>Conclusions: </strong>HH workload and performance rates were negatively correlated and changed drastically over hours in a day. Hospitals should consider HH workload in the development and timely delivery of improvement interventions.</p>","PeriodicalId":7621,"journal":{"name":"American journal of infection control","volume":" ","pages":"1371-1376"},"PeriodicalIF":4.3,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142144952","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Letter to Editor.","authors":"Karen deKay","doi":"10.1016/j.ajic.2024.08.005","DOIUrl":"10.1016/j.ajic.2024.08.005","url":null,"abstract":"","PeriodicalId":7621,"journal":{"name":"American journal of infection control","volume":" ","pages":"1475"},"PeriodicalIF":4.3,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142034934","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Marco Moretti, Robin Vanstokstraeten, Florence Crombé, Kurt Barbé, Ingrid Wybo, Sabine D Allard, Joop Jonckheer, Deborah De Geyter
{"title":"Five-year VIM-producing Pseudomonas aeruginosa outbreak in four Belgian ICUs, an investigation report (2019-2023).","authors":"Marco Moretti, Robin Vanstokstraeten, Florence Crombé, Kurt Barbé, Ingrid Wybo, Sabine D Allard, Joop Jonckheer, Deborah De Geyter","doi":"10.1016/j.ajic.2024.08.022","DOIUrl":"10.1016/j.ajic.2024.08.022","url":null,"abstract":"<p><strong>Background: </strong>Verona integron-encoded metallo-β-lactamase-producing Pseudomonas aeruginosa (VIM-PA) outbreaks are frequently linked to contaminated sink-drains in the intensive care unit (ICU). This study aims to investigate a VIM-PA outbreak occurring at 4 ICUs in a Belgian university center.</p><p><strong>Methods: </strong>Between 01/01/2019 and 30/07/2023, data were retrospectively retrieved. Whole-genome sequencing of VIM-PA was carried out for available isolates and the core genome multilocus sequencing typing (cgMLST) was used to confirm clonality. New case incidence was estimated by analyzing the weekly data of at-risk and VIM-PA-colonized patients, fitting a regression model.</p><p><strong>Results: </strong>Fifty-one patients were colonized, among them, 32 (63%) were infected by VIM-PA, which contributed to 7 deaths. The outbreak investigation showed that 19 (47%) of the examined sink-drains grew at least once a VIM-PA. Two major clusters were observed by cgMLST: ST111 (59 clones with 40 clinical isolates), and ST17 (8 clones with 6 clinical isolates). The estimated incidence rate of new cases was significantly higher in one unit.</p><p><strong>Conclusions: </strong>A 5-year prolonged outbreak at the UZ Brussel ICUs was caused by only 2 VIM-PA clones, both linked to sink-drains, with minimal mutations occurring throughout the years. Statistical modeling found different incidence rates between units. Tailored interventions were hence prioritized.</p>","PeriodicalId":7621,"journal":{"name":"American journal of infection control","volume":" ","pages":"1425-1431"},"PeriodicalIF":4.3,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142103545","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Weijia Shi, Michael Mackert, Deena Kemp, Andy J King, Yan Liu, Mike Henson-García, Jiahua Yang, Lindsay M Bouchacourt, Alison G Cahill
{"title":"\"Don't touch your face\"---Effectiveness of a health communication intervention on reducing face-touching behaviors.","authors":"Weijia Shi, Michael Mackert, Deena Kemp, Andy J King, Yan Liu, Mike Henson-García, Jiahua Yang, Lindsay M Bouchacourt, Alison G Cahill","doi":"10.1016/j.ajic.2024.08.021","DOIUrl":"10.1016/j.ajic.2024.08.021","url":null,"abstract":"<p><strong>Background: </strong>Given the risk of infection through face-touching behaviors, investigators have called for more research into the development of interventions to reduce the frequency of face-touching. The current study aims to test the effectiveness of messages on reducing face-touching behaviors.</p><p><strong>Methods: </strong>Nine different messages that highlighted the risk of face-touching were developed. Study 1, an online survey-experiment with a national sample of US adults (N = 998), examined message-, risk perceptions, and face-touching-related behavioral intentions. The most promising messages identified in study 1 were then tested in study 2, a follow-up behavioral observation study with a class of undergraduate students. Students' face-touching behaviors were observed during a 4-week period when intervention versus control messages were displayed in the classroom.</p><p><strong>Results: </strong>Four messages performed better in study 1, 2 of which were selected to test the actual message effectiveness in study 2. Study 2 results showed that on average, students touched their faces less frequently when a \"Don't touch your face\" message was present, although such decrease was not statistically significant.</p><p><strong>Conclusions: </strong>Having reminder messages of \"Don't touch your face\" in public spaces hold the potential to be a low-cost, effective strategy to reduce face-touching behaviors.</p>","PeriodicalId":7621,"journal":{"name":"American journal of infection control","volume":" ","pages":"1419-1424"},"PeriodicalIF":4.3,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142103544","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}