Victor Daniel Rosenthal, Ruijie Yin, Zhilin Jin, Mat Nor Mohd Basri, Lai Yin Hoong, Fatimah Mohamad, Amani El-Kholy, Victor Bayani, Rana Hatem, Sheila Nainan Myatra, Linda Castro Páez, Mohit Kharbanda, Bikas Nag, Ertugrul Guclu, Esra Olmez Gazioglu, Sunita Gupta, Nellie Tumu
{"title":"Multicenter, multinational, prospective cohort study of the impact of chlorhexidine impregnated versus plain central lines on central line-associated bloodstream infections.","authors":"Victor Daniel Rosenthal, Ruijie Yin, Zhilin Jin, Mat Nor Mohd Basri, Lai Yin Hoong, Fatimah Mohamad, Amani El-Kholy, Victor Bayani, Rana Hatem, Sheila Nainan Myatra, Linda Castro Páez, Mohit Kharbanda, Bikas Nag, Ertugrul Guclu, Esra Olmez Gazioglu, Sunita Gupta, Nellie Tumu","doi":"10.1016/j.ajic.2025.03.002","DOIUrl":"10.1016/j.ajic.2025.03.002","url":null,"abstract":"<p><strong>Background: </strong>We compared the efficacy of chlorhexidine-impregnated central lines (CLs) with plain CLs in preventing central line-associated bloodstream infections (CLABSIs) in critically ill patients.</p><p><strong>Methods: </strong>The study was conducted from April 2023 to August 2024 in 8 hospitals across India, Malaysia, Papua New Guinea, Colombia, Egypt, and Turkey. Data were collected prospectively using the INICC Surveillance Online System. Cases and controls were recruited simultaneously. Data were analyzed using t tests, χ² tests, and Fisher exact tests when indicated. Relative risks (RR) and their corresponding 95% confidence intervals (CI) were calculated.</p><p><strong>Results: </strong>A total of 6,672 patients were included. Patients with impregnated CLs had 4,721 CL-days, while those with plain CLs had 18,822 CL-days. The CLABSI rate in patients with impregnated CLs was 1.48 per 1,000 CL-days, compared to 4.78 per 1,000 CL-days in those with plain CLs (RR=0.31, 95%CI=0.14-0.67, P=.003). A subgroup analysis excluding patients with hemodialysis but using central venous catheters (CVCs) showed 1.72 CLABSIs per 1,000 CL-days in patients with impregnated CVCs compared to 5.84 per 1,000 CL-days in those with plain CVCs (RR=0.29, 95%CI=0.12-0.68, P=.004).</p><p><strong>Conclusions: </strong>This study highlights the significant benefits of impregnated CLs over plain CLs in reducing CLABSI rates, achieving a 69% decrease in incidence.</p>","PeriodicalId":7621,"journal":{"name":"American journal of infection control","volume":" ","pages":""},"PeriodicalIF":3.8,"publicationDate":"2025-03-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143584408","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jessica A Schults, Sally M Havers, Belinda C Henderson, Sally Healy, Naomi Runnegar, Trish Hurst, Karina Charles, Alison Smith, Julia E Clark, Robyn Birch, Joanne Campbell, Janine Carrucan, John Gamlin, Janice Geary, Christopher S Heather, Deborough A MacBeth, Kylie Maxwell, Paul Simpson, Sarah Smith, Josephine Lovegrove, Daner Ball, Lisa Hall, Claire M Rickard
{"title":"Expert consensus and recommendations for health care-associated infection surveillance in Queensland, Australia: A modified Delphi study.","authors":"Jessica A Schults, Sally M Havers, Belinda C Henderson, Sally Healy, Naomi Runnegar, Trish Hurst, Karina Charles, Alison Smith, Julia E Clark, Robyn Birch, Joanne Campbell, Janine Carrucan, John Gamlin, Janice Geary, Christopher S Heather, Deborough A MacBeth, Kylie Maxwell, Paul Simpson, Sarah Smith, Josephine Lovegrove, Daner Ball, Lisa Hall, Claire M Rickard","doi":"10.1016/j.ajic.2025.02.012","DOIUrl":"10.1016/j.ajic.2025.02.012","url":null,"abstract":"<p><strong>Background: </strong>Health care-associated infections (HAIs) continue to contribute significantly to Australia's burden of disease. In Queensland, varied surveillance protocols exist contributing to unnecessary complexity. With end-user partners, we defined a minimum dataset to support the public reporting of HAI surveillance data.</p><p><strong>Methods: </strong>A modified, 2-round Delphi study was conducted with field experts. In Round 1, infection control professionals and infectious disease physicians rated HAI measures on importance, feasibility, usefulness, and case definition acceptability using Likert scales. Measures meeting predefined thresholds progressed to Round 2, where a panel of experts achieved ≥70% consensus on the final dataset.</p><p><strong>Results: </strong>Forty-nine infection control professionals (nurses and physicians) responded in Round 1. From the originally proposed 36 HAI measures, 17 achieved consensus for importance, usefulness and feasibility. In Round 2, 14 experts (11 infection control practitioners; 3 physicians) met to review the 17 measures retained from Round 1. Final measures (n=13), meeting Round 2 consensus, included bloodstream infections, selected surgical site infections, and significant organisms.</p><p><strong>Conclusions: </strong>We developed a 13-item minimum dataset with standardized definitions to support consistent, state-wide HAI surveillance and reporting. The dataset supports efficient data aggregation and will inform targeted prevention activities.</p>","PeriodicalId":7621,"journal":{"name":"American journal of infection control","volume":" ","pages":""},"PeriodicalIF":3.8,"publicationDate":"2025-03-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143571863","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Microbial contamination in reusable health care bath basins: An observational descriptive study.","authors":"Hafsa Salim, Hafsa Rehman","doi":"10.1016/j.ajic.2025.02.014","DOIUrl":"10.1016/j.ajic.2025.02.014","url":null,"abstract":"","PeriodicalId":7621,"journal":{"name":"American journal of infection control","volume":" ","pages":""},"PeriodicalIF":3.8,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143539872","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Federico Cussotto, Costanza Vicentini, Luca Bresciano, Marta Castagnotto, Tommaso Cocchi, Dayana Indira Herr Ferrer, Carla Maria Zotti
{"title":"Ten-year-long implementation of a bundle for the prevention of surgical site infections: A cohort study of the temporal trend and factors influencing compliance.","authors":"Federico Cussotto, Costanza Vicentini, Luca Bresciano, Marta Castagnotto, Tommaso Cocchi, Dayana Indira Herr Ferrer, Carla Maria Zotti","doi":"10.1016/j.ajic.2025.02.013","DOIUrl":"10.1016/j.ajic.2025.02.013","url":null,"abstract":"<p><strong>Background: </strong>Many bundles have proven effective at preventing surgical site infections (SSIs), but little is known about factors influencing compliance to such bundles.</p><p><strong>Methods: </strong>This cohort study includes 41,400 surgeries performed in 47 hospitals throughout a decade. The outcome of interest was binary compliance with a 4-element bundle for SSI prevention. A multivariable logistic regression model was computed with 12 predictor variables: patient sex, age, American Society of Anesthesiologists score, surgical specialty, length of preoperative stay, procedure year, procedure duration, surgical technique, presence of a prosthetic implant, elective versus emergent procedure, hospital type, and hospital size.</p><p><strong>Results: </strong>Bundle compliance has increased significantly since its implementation, reaching 67.1% in the latest year. Lower odds of bundle compliance are correlated with emergent procedures (OR 0.3697), procedure duration above the first tertile (0.8597), age above the first quartile (0.7365), absence of a prosthetic implant, open surgical technique, and preoperative stay above 1 day (0.7920).</p><p><strong>Discussion: </strong>Older age, longer procedure duration, longer preoperative stay, and an open surgical technique all correlate negatively with bundle compliance and are also known risk factors for SSIs.</p><p><strong>Conclusions: </strong>Certain patient subgroups are at higher risk for bundle noncompliance, and thus show greater margins for improvement.</p>","PeriodicalId":7621,"journal":{"name":"American journal of infection control","volume":" ","pages":""},"PeriodicalIF":3.8,"publicationDate":"2025-02-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143536564","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Information for Authors","authors":"","doi":"10.1016/S0196-6553(25)00025-2","DOIUrl":"10.1016/S0196-6553(25)00025-2","url":null,"abstract":"","PeriodicalId":7621,"journal":{"name":"American journal of infection control","volume":"53 3","pages":"Pages A11-A12"},"PeriodicalIF":3.8,"publicationDate":"2025-02-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143474419","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Letter to the editor on “The impact of a novel color additive for disinfectant wipes on room cleanliness and turnover time”","authors":"Mahalakshmi Devaraji PhD , Nandhini Jayaprakash PhD","doi":"10.1016/j.ajic.2024.12.004","DOIUrl":"10.1016/j.ajic.2024.12.004","url":null,"abstract":"","PeriodicalId":7621,"journal":{"name":"American journal of infection control","volume":"53 3","pages":"Pages 413-414"},"PeriodicalIF":3.8,"publicationDate":"2025-02-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143474357","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Alberto Rizzo MS , Andrea De Vito MD , Riccardo Lucis MD , Davide Mileto MS , Andrea Giacomelli MD
{"title":"Chain of thought reasoning in enhancing infectious disease diagnosis and microbiological analysis","authors":"Alberto Rizzo MS , Andrea De Vito MD , Riccardo Lucis MD , Davide Mileto MS , Andrea Giacomelli MD","doi":"10.1016/j.ajic.2024.11.009","DOIUrl":"10.1016/j.ajic.2024.11.009","url":null,"abstract":"","PeriodicalId":7621,"journal":{"name":"American journal of infection control","volume":"53 3","pages":"Pages 411-412"},"PeriodicalIF":3.8,"publicationDate":"2025-02-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143474354","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Information for Readers","authors":"","doi":"10.1016/S0196-6553(25)00024-0","DOIUrl":"10.1016/S0196-6553(25)00024-0","url":null,"abstract":"","PeriodicalId":7621,"journal":{"name":"American journal of infection control","volume":"53 3","pages":"Page A8"},"PeriodicalIF":3.8,"publicationDate":"2025-02-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143474339","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Sari Luthfiyah M.Sc. , Triwiyanto Ph.D. , Aini Ahmad Ph.D
{"title":"The impact of a novel color additive for disinfectant wipes on room cleanliness and turnover time [Letter]","authors":"Sari Luthfiyah M.Sc. , Triwiyanto Ph.D. , Aini Ahmad Ph.D","doi":"10.1016/j.ajic.2024.11.012","DOIUrl":"10.1016/j.ajic.2024.11.012","url":null,"abstract":"","PeriodicalId":7621,"journal":{"name":"American journal of infection control","volume":"53 3","pages":"Page 413"},"PeriodicalIF":3.8,"publicationDate":"2025-02-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143474356","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}