American journal of infection control最新文献_第3页

Reply to comment on “Estimating individual risk of catheter-associated urinary tract infections using explainable artificial intelligence on clinical data” 回复“基于临床数据的可解释人工智能评估导尿管相关性尿路感染个体风险”评论

IF 3.8 3区医学

American journal of infection control Pub Date : 2025-06-13 DOI: 10.1016/j.ajic.2025.03.152

Herdiantri Sufriyana MD, PhD , Chieh Chen MD , Hua-Sheng Chiu PhD , Pavel Sumazin PhD , Po-Yu Yang MD , Jiunn-Horng Kang MD, PhD , Emily Chia-Yu Su PhD

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Reply to: “Coagulase-negative Staphylococcus bacteremia in ECMO: Examining key influencing factors” 回复：《ECMO中凝固酶阴性葡萄球菌血症：探讨关键影响因素》

IF 3.8 3区医学

American journal of infection control Pub Date : 2025-06-13 DOI: 10.1016/j.ajic.2025.03.016

Christian B. Wells MD , Joseph E. Marcus MD

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Outbreak of New Delhi metallo-β-lactamase carbapenemase-producing Pseudomonas aeruginosa infections in a Southern California hospital. 在南加州一家医院爆发的新德里产金属β-内酰胺酶碳青霉烯酶铜绿假单胞菌感染。

IF 3.8 3区医学

American journal of infection control Pub Date : 2025-06-13 DOI: 10.1016/j.ajic.2025.06.005

Jacob M Garrigues, Hannah K Gray, Ricardo P Ison, Daniel Z Uslan, Amorce Lima, Shekina Gonzalez-Ferrer, Marisol Trejo, Ran Zhuo, Colette J Matysiak Match, Erlinda R Ulloa, Sandeep Bhaurla, Vanessa Lewis, Urvashi Parti, Tessa Sandoval, Sebora Turay, Shaunté Walton, Kavitha Prabaker, Omai B Garner, Sukantha Chandrasekaran, Nicole M Green, Shangxin Yang

{"title":"Outbreak of New Delhi metallo-β-lactamase carbapenemase-producing Pseudomonas aeruginosa infections in a Southern California hospital.","authors":"Jacob M Garrigues, Hannah K Gray, Ricardo P Ison, Daniel Z Uslan, Amorce Lima, Shekina Gonzalez-Ferrer, Marisol Trejo, Ran Zhuo, Colette J Matysiak Match, Erlinda R Ulloa, Sandeep Bhaurla, Vanessa Lewis, Urvashi Parti, Tessa Sandoval, Sebora Turay, Shaunté Walton, Kavitha Prabaker, Omai B Garner, Sukantha Chandrasekaran, Nicole M Green, Shangxin Yang","doi":"10.1016/j.ajic.2025.06.005","DOIUrl":"10.1016/j.ajic.2025.06.005","url":null,"abstract":"Background: Carbapenemase-producing carbapenem-resistant Pseudomonas aeruginosa (CP-CRPA) is a major public health threat due to limited treatment options and high transmissibility. Though widespread globally, few instances of locally transmitted New Delhi metallo-β-lactamase (NDM)-producing CP-CRPA have been documented in the United States. Here, a cluster of locally transmitted NDM-1 CP-CRPA infections in Southern California is reported.Methods: Epidemiologic investigations involving both patient screening and environmental surveillance by microbiological culture, carbapenemase testing, and bacterial whole-genome sequencing were conducted.Results: Through extensive epidemiologic investigations, a sink environmental reservoir was identified. A genetically unique strain of NDM-CRPA was identified to be transmitted among seven patients in a single hospital over the course of 1.5 years. Changes in antimicrobial resistance genes harbored by a mobile genetic element were identified between the index and later cases, and the gene encoding NDM-1 resided within a mobile genetic element on the chromosome displaying evidence of widespread transmission between different species. Several interventions were implemented, including sink P-trap replacement and disinfectant against Pseudomonas biofilms. No additional cases were identified after the interventions.Conclusions: Implementation of real-time pathogen surveillance enabled effective response to an ongoing outbreak that involved environmental sampling, microbiological testing, whole-genome sequencing, facility management, and updated infection prevention policies.","PeriodicalId":7621,"journal":{"name":"American journal of infection control","volume":" ","pages":""},"PeriodicalIF":3.8,"publicationDate":"2025-06-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144301015","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

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IF 3.8 3区医学

American journal of infection control Pub Date : 2025-06-13 DOI: 10.1016/S0196-6553(25)00382-7

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APIC Masthead APIC报头

IF 3.8 3区医学

American journal of infection control Pub Date : 2025-06-13 DOI: 10.1016/S0196-6553(25)00380-3

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Hospital-acquired COVID-19 is associated with increased length and cost of stay in an Australian health care setting. 医院获得性COVID-19与澳大利亚医疗保健机构住院时间和费用增加有关。

IF 3.8 3区医学

American journal of infection control Pub Date : 2025-06-11 DOI: 10.1016/j.ajic.2025.06.004

George P Drewett, Mani Suleiman, Anthony Gust, Adam King, Saliya Hewagama, Craig Aboltins

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Provincial PPE Safety Coach Program evaluation in continuing care settings in Alberta. 艾伯塔省持续护理环境中的省级个人防护装备安全教练项目评估。

IF 3.8 3区医学

American journal of infection control Pub Date : 2025-06-06 DOI: 10.1016/j.ajic.2025.06.002

Kaethel Decker, Heather Gagnon, Abram Gutscher, Meaghan Brierley, Sara Mallinson, Jenine Leal

{"title":"Provincial PPE Safety Coach Program evaluation in continuing care settings in Alberta.","authors":"Kaethel Decker, Heather Gagnon, Abram Gutscher, Meaghan Brierley, Sara Mallinson, Jenine Leal","doi":"10.1016/j.ajic.2025.06.002","DOIUrl":"10.1016/j.ajic.2025.06.002","url":null,"abstract":"Background: Alberta Health Services (AHS) offered the Provincial Personal Protective Equipment (PPE) Safety Coach Program to continuing care homes to provide support to staff regarding the safe and appropriate use of PPE.Methods: A mixed-methods approach was used to evaluate staff experiences of training, adoption, and perceived impact of the program. Data were gathered using an online survey and semistructured qualitative interviews. The evaluation drew on implementation science frameworks to review implementation processes and contextual factors influencing program uptake and participant experiences.Results: A total of 283 surveys and 22 qualitative interviews were completed. Key findings are grouped into the following categories: program uptake, program content and delivery, skills and knowledge, the program's perceived impact, and feedback from nonadopting sites.Conclusions: Trained staff were largely satisfied with the delivery and content of the modules and other staff indicated it was beneficial to have support from trained staff. Sites that did not adopt the program indicated that the timing of the launch, ongoing staffing challenges, and the use of alternative PPE training were barriers to uptake.","PeriodicalId":7621,"journal":{"name":"American journal of infection control","volume":" ","pages":""},"PeriodicalIF":3.8,"publicationDate":"2025-06-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144245793","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

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The CONSIDER study: Assessing the risk of catheter-associated bloodstream infections beyond the intensive care setting. 考虑研究：评估重症监护环境之外导管相关血流感染的风险。

IF 3.8 3区医学

American journal of infection control Pub Date : 2025-06-06 DOI: 10.1016/j.ajic.2025.05.020

Fabio Borgonovo, Marta Colaneri, Federico Fassio, Giovanni Scaglione, Lucia Galli, Martina Offer, Camilla Genovese, Rebecca Fattore, Monica Schiavini, Giovanni De Capitani, Maria Calloni, Arianna Bartoli, Francesco Casella, Alba Taino, Antonio Gidaro, Chiara Cogliati, Valentina Breschi, Jessica Leoni, Andrea Gori, Antonella Foschi

{"title":"The CONSIDER study: Assessing the risk of catheter-associated bloodstream infections beyond the intensive care setting.","authors":"Fabio Borgonovo, Marta Colaneri, Federico Fassio, Giovanni Scaglione, Lucia Galli, Martina Offer, Camilla Genovese, Rebecca Fattore, Monica Schiavini, Giovanni De Capitani, Maria Calloni, Arianna Bartoli, Francesco Casella, Alba Taino, Antonio Gidaro, Chiara Cogliati, Valentina Breschi, Jessica Leoni, Andrea Gori, Antonella Foschi","doi":"10.1016/j.ajic.2025.05.020","DOIUrl":"10.1016/j.ajic.2025.05.020","url":null,"abstract":"Background: Catheter-associated and related bloodstream infection (CABSI and CRBSI) are major causes of hospital-acquired infections. However, their incidence and risk factors in non-intensive care unit (ICU) patients with vascular access devices (VADs) remain unclear.Methods: This retrospective study evaluated CABSI and CRBSI incidence and risk factors in non-ICU hospitalized adults with VADs. Hazard ratios (HR) were estimated with gamma frailty models and random survival forest analysis. Key variables were identified and validated in multivariable models.Results: Among 2,326 VAD insertions (1,892 patients), 153 with CRBSI or CABSI were identified. The incidence was 1.80 per 1,000 catheter-days for CABSI, 1.24 for CRBSI, and 2.97 overall. Coagulase-negative Staphylococci were the most isolated pathogens (43.9%). Infections were associated with parenteral nutrition (PN) (HR = 4.12) and multilumen catheters (HR = 2.56). Random survival forest models identified PN, intravenous drug use, and in-patient regimen as top variables. CRBSI was strongly associated with PN (HR = 7.42), while CABSI was linked to intravenous drug use (HR = 7.20).Conclusions: Our study showed a high incidence of CABSI and CRBSI in non-ICU adult patients. Identifying risk factors highlights the settings where stringent infection prevention strategies are needed.","PeriodicalId":7621,"journal":{"name":"American journal of infection control","volume":" ","pages":""},"PeriodicalIF":3.8,"publicationDate":"2025-06-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144245794","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Environmental detection and genetic profiling of Acanthamoeba in high-risk medical facilities. 高风险医疗机构棘阿米巴的环境检测与基因分析

IF 3.8 3区医学

American journal of infection control Pub Date : 2025-06-06 DOI: 10.1016/j.ajic.2025.05.022

Sara Sareminejad, Farnaz Kheirandish, Amirreza Javadi Mamaghani, Maryam Niyyati, Farzad Ebrahimzadeh, Mohammad Yarahmadi, Azadeh Karimi, Syedeh Fatemeh Moosavi, Nozhat Zebardast, Shirzad Fallahi

{"title":"Environmental detection and genetic profiling of Acanthamoeba in high-risk medical facilities.","authors":"Sara Sareminejad, Farnaz Kheirandish, Amirreza Javadi Mamaghani, Maryam Niyyati, Farzad Ebrahimzadeh, Mohammad Yarahmadi, Azadeh Karimi, Syedeh Fatemeh Moosavi, Nozhat Zebardast, Shirzad Fallahi","doi":"10.1016/j.ajic.2025.05.022","DOIUrl":"10.1016/j.ajic.2025.05.022","url":null,"abstract":"Background: Acanthamoeba parasite, one of the most common environmental protozoans, can be isolated from contact lenses, cleaning solutions, ventilation systems, dental treatment units, dialysis units, and emergency showers. Since the genus Acanthamoeba can lead to dangerous infectious diseases in immunocompromised patients, monitoring medical centers and hospitals admitting these patients, is of great importance.Methods: In this study, 53 dust samples were collected from 4 high-risk health care facilities in Khorramabad City, Western Iran. The samples were cultured in a non-nutritive agar culture medium, and samples with positive cultures were selected for molecular analysis. PCR and LAMP targeting 18srRNA gene-specific primers were used to analyze the samples.Results: The culture and microscopic examination showed that 31 out of 53 samples (58.5%) collected were positive for the Acanthamoeba parasite. All the positive samples by the culture method were also positive in the PCR assay. Out of 53 examined samples, 26 were positive by the LAMP technique regarding the presence of the Acanthamoeba parasite. Sequencing results of 4 sequenced samples showed T4 genotypes, Acanthamoeba sp, and Acanthamoeba culbertsoni.Conclusions: The present study showed that the environment of high-risk health care facilities in Khorramabad city is contaminated with Acanthamoeba, and the pathogenic T4 genotype is present among the positive samples.","PeriodicalId":7621,"journal":{"name":"American journal of infection control","volume":" ","pages":""},"PeriodicalIF":3.8,"publicationDate":"2025-06-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144245791","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

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Interventions to prevent bloodstream infections associated with central venous access devices: Priorities for an adaptive platform trial. 预防与中心静脉通路装置相关的血流感染的干预措施：适应性平台试验的优先事项。

IF 3.8 3区医学

American journal of infection control Pub Date : 2025-06-06 DOI: 10.1016/j.ajic.2025.06.003

Claire M Rickard, Andrew J Stewardson, Sally M Havers, Niccolo Buetti, Kevan R Polkinghorne, Aleece MacPhail, Zoe McQuilten, Benjamin Lazarus, Karina R Charles, Jessica A Schults

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