Theresa Murillo, Krishnendu Mangal, Gabrielle Barmada, Tracy Morris, Kady D Waggle, Marissa Griffith, Lora Lee Pless, Lee H Harrison, Rebecca Glista, Brian Wilson, Graham Snyder, David A Nace
{"title":"Transmission of Group A Streptococcus in Long-Term Care: An Outbreak Investigation.","authors":"Theresa Murillo, Krishnendu Mangal, Gabrielle Barmada, Tracy Morris, Kady D Waggle, Marissa Griffith, Lora Lee Pless, Lee H Harrison, Rebecca Glista, Brian Wilson, Graham Snyder, David A Nace","doi":"10.1016/j.ajic.2024.11.008","DOIUrl":"https://doi.org/10.1016/j.ajic.2024.11.008","url":null,"abstract":"<p><p>We report two outbreaks comprising a cluster of 18 group A streptococcal infections across two nursing facilities. Point prevalence surveillance testing identified 8 of 18 cases, and whole genome sequencing validated transmission pathways. Infection prevention interventions at the facility level comprised symptomatic and asymptomatic carriage-based case finding, transmission-based precautions, and treatment to eradicate colonization.</p>","PeriodicalId":7621,"journal":{"name":"American journal of infection control","volume":" ","pages":""},"PeriodicalIF":3.8,"publicationDate":"2024-11-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142692612","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Xin Du, Lu Tang, Huan Wang, Li Yan, Lei Wang, Wei He, Xi Zhang, Caiping Song
{"title":"Compliance with standard precautions among hematology nurses: A cross-sectional study.","authors":"Xin Du, Lu Tang, Huan Wang, Li Yan, Lei Wang, Wei He, Xi Zhang, Caiping Song","doi":"10.1016/j.ajic.2024.11.010","DOIUrl":"10.1016/j.ajic.2024.11.010","url":null,"abstract":"<p><strong>Background: </strong>Standard precautions (SP) are an important method for preventing and controlling hospital infections. However, the level of compliance with standard precautions in haematology nurses is not high. This study identified various types of hematological nurses in Chongqing and the factors that influence their compliance with SP.</p><p><strong>Methods: </strong>Hematology nurses from 33 Chongqing central hospitals were chosen as study participants for a cross-sectional survey in November 2022. Latent class, univariate and logistic regression were used to analyze nurses' SP compliance and its influencing factors.</p><p><strong>Results: </strong>With a 98% response rate, we gathered 702 valid surveys in total. The compliance with nurses' SP was classified into 2 latent classes: low (42.1%) and high (56.9%). The results of binary logistic regression analysis revealed that recruitment methods, participation in standard preventive knowledge training, organizational support, depersonalization, and personal achievement were the main factors influencing compliance with nurses' SP (P < .05).</p><p><strong>Conclusions: </strong>Hematology nurses demonstrated modest compliance with SP, with some variation. Nursing management should monitor the compliance characteristics of various nurses' SP, adopt targeted intervention strategies, and improve SP compliance.</p>","PeriodicalId":7621,"journal":{"name":"American journal of infection control","volume":" ","pages":""},"PeriodicalIF":3.8,"publicationDate":"2024-11-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142692607","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Subhadra Mandadi, Mark E Rupp, Barbara Wolford, Elizabeth Lyden, Rick Starlin
{"title":"Effect of the COVID-19 pandemic on occupational risk for bloodborne pathogen exposure among health care providers.","authors":"Subhadra Mandadi, Mark E Rupp, Barbara Wolford, Elizabeth Lyden, Rick Starlin","doi":"10.1016/j.ajic.2024.11.007","DOIUrl":"10.1016/j.ajic.2024.11.007","url":null,"abstract":"<p><strong>Background: </strong>The effect of COVID-19 (COrona VIrus Disease of 2019) pandemic on the rates and trends of needlestick and sharp injuries (NSSIs) and splash injuries (SIs) among health care providers (HCPs) is not well defined.</p><p><strong>Methods: </strong>A retrospective study analyzed the rates of injuries among HCPs during the prepandemic (38 months) and pandemic (37 months) periods. Single interrupted time-series analysis (SITSA) was employed to assess the impact of the pandemic on injury rates.</p><p><strong>Results: </strong>During the prepandemic and pandemic periods, 608 and 637 NSSIs and 137 and 120 SIs were reported, respectively. No statistically significant difference was identified in the median monthly rates of NSSIs (0.34 vs 0.37, P = .622) and SIs (0.075 vs 0.047, P = .094) per 1,000 inpatient days, nor their combined risk (0.439 vs 0.434, P = .449). The SITSA indicated a marginally significant trend during the pandemic, with a monthly 0.0028% decrease in NSSI/SI rates (P = .059). Subsequent SITSA revealed significant pandemic changes in NSSIs , with rates rising early (P = .016) and falling marginally later (P = .051).</p><p><strong>Conclusions: </strong>We report no statistically significant difference in the rates of NSSIs/SIs between the prepandemic and pandemic periods. HCPs remain at risk for occupational injuries, emphasizing targeted training and well-designed infection control policies.</p>","PeriodicalId":7621,"journal":{"name":"American journal of infection control","volume":" ","pages":""},"PeriodicalIF":3.8,"publicationDate":"2024-11-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142646688","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Axel Kramer, Mathilde Borg Dahl, Mia M Bengtsson, John M Boyce, Matthias Heckmann, Mareike Meister, Roald Papke, Didier Pittet, Anne Reinhard, Hortense Slevogt, Haitao Wang, Paula Zwicker, Tim Urich, Ulrike Seifert
{"title":"No detrimental effect on the hand microbiome of health care staff by frequent alcohol-based antisepsis.","authors":"Axel Kramer, Mathilde Borg Dahl, Mia M Bengtsson, John M Boyce, Matthias Heckmann, Mareike Meister, Roald Papke, Didier Pittet, Anne Reinhard, Hortense Slevogt, Haitao Wang, Paula Zwicker, Tim Urich, Ulrike Seifert","doi":"10.1016/j.ajic.2024.11.006","DOIUrl":"10.1016/j.ajic.2024.11.006","url":null,"abstract":"<p><strong>Background: </strong>The importance of ethanol-based hand rubs (EBHRs) to prevent health care-associated infections is undisputed. However, there is a lack of meaningful data regarding the influence of EBHRs on skin microbiome.</p><p><strong>Methods: </strong>Four nurses in a neonatal intensive care unit were included. After a leave of 14 days, samples were taken before the first hand rubbing action and at the end of shift, with continued sampling on days 1, 7, and 28. To analyze the hand microbiome, microbial cells were collected using the glove-juice technique. Pro- and eukaryotic community profiles were created using amplicon sequencing of 16S and 18S ribosomal RNA (rRNA) gene markers.</p><p><strong>Results: </strong>On average, hand antisepsis was performed 108 times per 8-hour work shift. Microbial communities were dominated by typical taxa found on human skin. In addition, a clear nurse-specific (ie, individual) microbiome signature could be observed. For Prokaryota, daily exposure led to the end-of-the-day microbiomes being more similar to each other across nurses. In contrast, longitudinal effect of 28-day application revealed more similarity of the Eukaryotic community.</p><p><strong>Conclusions: </strong>Frequent occupational use of EBHR did not adversely affect the composition of the human hand microbiome. Thus, daily hand antisepsis retains its significance as the most important procedure for infection control.</p>","PeriodicalId":7621,"journal":{"name":"American journal of infection control","volume":" ","pages":""},"PeriodicalIF":3.8,"publicationDate":"2024-11-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142646689","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Zainab Said Al-Hashimy, Mubarak Al-Yaqoobi, Amal Al Jabari, Nawal Al Kindi, Ahmed Saleh Al Kazrooni, Barbara R Conway, Feras Darwish Elhajji, Stuart E Bond, William J Lattyak, Mamoon A Aldeyab
{"title":"Threshold modeling for antibiotic stewardship in Oman.","authors":"Zainab Said Al-Hashimy, Mubarak Al-Yaqoobi, Amal Al Jabari, Nawal Al Kindi, Ahmed Saleh Al Kazrooni, Barbara R Conway, Feras Darwish Elhajji, Stuart E Bond, William J Lattyak, Mamoon A Aldeyab","doi":"10.1016/j.ajic.2024.11.005","DOIUrl":"10.1016/j.ajic.2024.11.005","url":null,"abstract":"<p><strong>Background: </strong>Antimicrobial stewardship supports rational antibiotic use. However, balancing access to antibiotic treatment while controlling resistance is challenging. This research used a threshold logistic modeling approach to identify targets for antibiotic usage associated with carbapenem-resistant Acinetobacter baumannii, carbapenem-resistant Klebsiella pneumonia, and extended-spectrum β-lactamases-producing Escherichia coli incidence in hospitals.</p><p><strong>Methods: </strong>This study utilizes an ecological population-level design. Monthly pathogen cases and antibiotic use were retrospectively determined for inpatients between January 2015 and December 2023. The hospital pharmacy and microbiology information systems were used to obtain this data. Thresholds were identified by applying nonlinear modeling and logistic regression.</p><p><strong>Results: </strong>Incidence rates of 0.199, 0.175, and 0.146 cases/100 occupied bed-days (OBD) for carbapenem-resistant A baumannii, carbapenem-resistant K pneumonia, and extended-spectrum β-lactamases-producing E coli, respectively, were determined as the cutoff values for high (critical) incidence rates. Thresholds for aminoglycosides (0.59 defined daily dose [DDD]/100 OBD), carbapenems (6.31 DDD/100 OBD), piperacillin-tazobactam (3.71 DDD/100 OBD), third-generation cephalosporins (3.71 DDD/100 OBD), and fluoroquinolones (1.91 DDD/100 OBD), were identified. Exceeding these thresholds would accelerate the gram-negative pathogens' incidence rate above the critical incidence levels.</p><p><strong>Conclusions: </strong>Threshold logistic models can help inform and implement effective antimicrobial stewardship interventions to manage resistance within hospital settings.</p>","PeriodicalId":7621,"journal":{"name":"American journal of infection control","volume":" ","pages":""},"PeriodicalIF":3.8,"publicationDate":"2024-11-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142643241","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Response to the letter to the editor regarding “The efficacy of an alcohol-based nasal antiseptic versus mupirocin or an iodophor for preventing SSIs using a meta-analysis”","authors":"Karen K. Hoffmann MS, BSN, RN, CIC, FAPIC, FSHEA","doi":"10.1016/j.ajic.2024.08.017","DOIUrl":"10.1016/j.ajic.2024.08.017","url":null,"abstract":"","PeriodicalId":7621,"journal":{"name":"American journal of infection control","volume":"52 12","pages":"Pages 1475-1476"},"PeriodicalIF":3.8,"publicationDate":"2024-11-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142638544","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Letter to the editor on National trends and disparities in herpes zoster vaccination among US older adults with chronic obstructive pulmonary disease (COPD), 2008 to 2022","authors":"Rajesh Kanna Gopal PhD, Pitchaipillai Sankar Ganesh PhD, Naji Naseef Pathoor MSc, Akshaya Viswanathan MSc","doi":"10.1016/j.ajic.2024.09.006","DOIUrl":"10.1016/j.ajic.2024.09.006","url":null,"abstract":"","PeriodicalId":7621,"journal":{"name":"American journal of infection control","volume":"52 12","pages":"Pages 1477-1478"},"PeriodicalIF":3.8,"publicationDate":"2024-11-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142638542","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Information for Authors","authors":"","doi":"10.1016/S0196-6553(24)00785-5","DOIUrl":"10.1016/S0196-6553(24)00785-5","url":null,"abstract":"","PeriodicalId":7621,"journal":{"name":"American journal of infection control","volume":"52 12","pages":"Pages A13-A14"},"PeriodicalIF":3.8,"publicationDate":"2024-11-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142723612","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Information for Readers","authors":"","doi":"10.1016/S0196-6553(24)00784-3","DOIUrl":"10.1016/S0196-6553(24)00784-3","url":null,"abstract":"","PeriodicalId":7621,"journal":{"name":"American journal of infection control","volume":"52 12","pages":"Page A10"},"PeriodicalIF":3.8,"publicationDate":"2024-11-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142723611","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Response to the letter to the editor on “National trends and disparities in herpes zoster vaccination among US older adults with chronic obstructive pulmonary disease, 2008 to 2022”","authors":"Chun-Tse Hung PharmD","doi":"10.1016/j.ajic.2024.09.005","DOIUrl":"10.1016/j.ajic.2024.09.005","url":null,"abstract":"","PeriodicalId":7621,"journal":{"name":"American journal of infection control","volume":"52 12","pages":"Page 1478"},"PeriodicalIF":3.8,"publicationDate":"2024-11-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142638543","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}