Rachel Yoken BA , Caroline A. O’Neil MA, MPH , Kate Peacock MPH , Candice Cass BS , Meghan A. Wallace BS , Kelly Alvarado BS , Mostafa Amor BS , Emily Struttmann BA , Daniel Park BS , David McDonald BA , Karl Hock BA , Hilary Babcock MD, MPH , Carey-Ann D. Burnham PhD , Christopher W. Farnsworth PhD , Jennie H. Kwon DO, MSCI
{"title":"SARS-CoV-2 PCR and antibody positivity in asymptomatic health care workers with a known SARS-CoV-2 exposure: December, 2020 to December, 2021","authors":"Rachel Yoken BA , Caroline A. O’Neil MA, MPH , Kate Peacock MPH , Candice Cass BS , Meghan A. Wallace BS , Kelly Alvarado BS , Mostafa Amor BS , Emily Struttmann BA , Daniel Park BS , David McDonald BA , Karl Hock BA , Hilary Babcock MD, MPH , Carey-Ann D. Burnham PhD , Christopher W. Farnsworth PhD , Jennie H. Kwon DO, MSCI","doi":"10.1016/j.ajic.2025.07.005","DOIUrl":null,"url":null,"abstract":"<div><div>In this prospective cohort study, 30 health care personnel with a known SARS-CoV-2 exposure provided oropharyngeal swabs for polymerase chain reaction (PCR) testing and blood specimens for serologic testing at 2 time points postexposure. At a median 7<!--> <!-->days postexposure (range, 1-13<!--> <!-->days), none had a positive PCR and 1 (3%) had a reactive antibody test. No additional participants were PCR or antibody-positive at a median 25<!--> <!-->days postexposure (range, 14-36<!--> <!-->days).</div></div>","PeriodicalId":7621,"journal":{"name":"American journal of infection control","volume":"53 10","pages":"Pages 1124-1126"},"PeriodicalIF":2.4000,"publicationDate":"2025-07-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"American journal of infection control","FirstCategoryId":"3","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0196655325004730","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"INFECTIOUS DISEASES","Score":null,"Total":0}
引用次数: 0
Abstract
In this prospective cohort study, 30 health care personnel with a known SARS-CoV-2 exposure provided oropharyngeal swabs for polymerase chain reaction (PCR) testing and blood specimens for serologic testing at 2 time points postexposure. At a median 7 days postexposure (range, 1-13 days), none had a positive PCR and 1 (3%) had a reactive antibody test. No additional participants were PCR or antibody-positive at a median 25 days postexposure (range, 14-36 days).
期刊介绍:
AJIC covers key topics and issues in infection control and epidemiology. Infection control professionals, including physicians, nurses, and epidemiologists, rely on AJIC for peer-reviewed articles covering clinical topics as well as original research. As the official publication of the Association for Professionals in Infection Control and Epidemiology (APIC)