单点采样策略与多点采样策略在医院血液培养收集：一个系统的回顾。

IF 2.4 3区医学 Q2 INFECTIOUS DISEASES

American journal of infection control Pub Date : 2025-07-30 DOI:10.1016/j.ajic.2025.07.010

Anniella Vashti MD, RN, Judy Mullan PhD, FSHPA, BS, BPharm, GAICD, Michael Nitzberg FACEM, FACEP

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引用次数: 0

摘要

背景：许多全球传染病和脓毒症指南建议采用多点采样（MSS）血液培养策略来诊断血流感染，然而，单点采样（SSS）可能是一种可行的选择。这篇系统综述的目的是确定比较SSS和MSS的文献现状。方法：检索MEDLINE、CINAHL、Pubmed、Web of Science、Scopus、谷歌Scholar等数据库，检索时间为建站至2023年8月。比较医院环境中成人患者的SSS和MSS的研究包括在内。比较的主要结果是菌血症检测、污染率和收集的样品量。结果：7项研究符合纳入标准，共纳入受试者18901人，血培养样本24955份。尽管收集方法存在差异，但七项研究中有五项强调，使用SSS技术增加血容量可以改善病原体检测并降低污染率。评估的研究质量不同，存在潜在偏倚。结论：本系统综述表明，血液培养收集的SSS技术在不增加污染的情况下提供了相似的菌血症检出率，如果不是改进的话。我们建议在未来的指南出版物中考虑上述证据。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Single-site sampling strategy versus multisite sampling strategy in blood culture collection within the hospital setting: A systematic review

Background

Many global infectious disease and sepsis guidelines suggest a multisite sampling (MSS) strategy of blood cultures to diagnose bloodstream infections, however, single-site sampling (SSS) may be a viable alternative. This systematic review aims to identify the current state of literature comparing SSS to MSS.

Methods

MEDLINE, CINAHL, Pubmed, Web of Science, Scopus, and Google Scholar were searched from inception to August 2023. Studies comparing SSS and MSS in hospital settings among adult patients were included. Key outcomes being compared were bacteremia detection, contamination rates, and volume of sample collected.

Results

Seven studies met the inclusion criteria and were selected, with a total of 18,901 participants and 24,955 blood culture samples. Despite differences in collection methods, 5 out of 7 studies highlighted that increased blood volume using the SSS technique improves pathogen detection and lowers contamination rates. The studies evaluated were of variable quality with potential bias.

Conclusions

This systematic review demonstrates that the SSS technique for blood culture collection provides similar, if not improved, rates of bacteremia detection without increased contamination. We recommend that the above evidence is considered in future guideline publications.

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来源期刊

American journal of infection control 医学-传染病学

CiteScore

7.40

自引率

4.10%

发文量

479

审稿时长

24 days

期刊介绍： AJIC covers key topics and issues in infection control and epidemiology. Infection control professionals, including physicians, nurses, and epidemiologists, rely on AJIC for peer-reviewed articles covering clinical topics as well as original research. As the official publication of the Association for Professionals in Infection Control and Epidemiology (APIC)