Mohammad Hashemi, Saeed Jafari, Hamidreza Mokarami, Amir Omidvar, Zabiholla Damiri
{"title":"Development and validation of an Operating Room Ventilation System Assessment (ORVSA) tool: A comprehensive checklist for surgical site infection prevention.","authors":"Mohammad Hashemi, Saeed Jafari, Hamidreza Mokarami, Amir Omidvar, Zabiholla Damiri","doi":"10.1016/j.ajic.2025.08.010","DOIUrl":"10.1016/j.ajic.2025.08.010","url":null,"abstract":"<p><strong>Background: </strong>Surgical site infections (SSIs) can lead to increased mortality rates, extended hospital stays, and higher health care costs. Application of an effective operating room (OR) ventilation system is a crucial prevention strategy for SSIs, but standardized assessment tools are lacking.</p><p><strong>Methods: </strong>A mixed-methods sequential exploratory design was used. The qualitative phase included literature and standards review and expert panel discussions to identify key domains and items. The quantitative phase assessed psychometric properties, including content validity and reliability. Sixty-four ORs across 7 hospitals were evaluated.</p><p><strong>Results: </strong>The ORVSA (Operating Room Ventilation System Assessment) tool comprises 7 domains and 44 items, covering ventilation type, exhaust systems, managerial factors, standard criteria, filtration, air handling units, and anesthetic gas management. The tool demonstrated excellent content validity (mean CVI = 0.959, mean CVR = 0.936) and high reliability (Cohen's Kappa coefficient = 0.963, test-retest reliability = 0.949).</p><p><strong>Discussion: </strong>Validation of the tool's items by a qualified and heterogeneous expert panel, demonstrating high relevance, simplicity, and clarity, and consistent inter-rater correlations confirm the tool's validity in accurately measuring its intended purpose.</p><p><strong>Conclusions: </strong>The ORVSA tool provides a comprehensive and user-friendly method for assessing OR ventilation systems, ensuring compliance with standards and identifying areas for improvement. Its strong psychometric properties make it a valuable resource for reducing SSIs and enhancing patient safety.</p>","PeriodicalId":7621,"journal":{"name":"American journal of infection control","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2025-08-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144938951","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Dalton Butcher, Lauren DiBiase, Melissa B Miller, Emily Sickbert-Bennett
{"title":"Trends in rhinovirus/enterovirus health care-associated infections at a large academic hospital from July 2018 to June 2024.","authors":"Dalton Butcher, Lauren DiBiase, Melissa B Miller, Emily Sickbert-Bennett","doi":"10.1016/j.ajic.2025.08.012","DOIUrl":"10.1016/j.ajic.2025.08.012","url":null,"abstract":"<p><p>This report identifies rhinovirus/enterovirus as the second most prevalent cause of health care-associated respiratory viral infections (HA-RVIs) at a large academic hospital with > 950 inpatient beds, after SARS-CoV-2 from FY 2019-2024. Here, we describe trends in rhinovirus/enterovirus HA-RVIs over time and compare rhinovirus/enterovirus HA-RVI incidence rates in pediatric and adult patients.</p>","PeriodicalId":7621,"journal":{"name":"American journal of infection control","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2025-08-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144870902","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Worldwide antibiotic prescription practices in primary care and associated factors: A systematic review and meta-analysis.","authors":"Qihua Song, Jinxi Li, Pengfei Zhou, Rui Chen, Zhen Liu, Hui Li, Xiaoxv Yin","doi":"10.1016/j.ajic.2025.08.009","DOIUrl":"10.1016/j.ajic.2025.08.009","url":null,"abstract":"<p><strong>Background: </strong>Antibiotic prescription is a major driver of antimicrobial resistance. However, evidence on antibiotic prescription practices is inadequate globally. This study aimed to assess antibiotic prescription practices and identify its associated factors in primary care worldwide.</p><p><strong>Methods: </strong>PubMed, Embase, Web of science, and Global Index Medicus by WHO were searched from studies published between January 2000 and September 2023. Quantitative studies that investigated the antibiotic prescriptions practices were included in this study. Each study was assessed by at least 2 independent reviewers. Risk of bias was assessed using a modified Hoy tool. Quantitative studies were merged using Meta-analysis with random effects modeling. This study was registered with PROSPERO, CRD42022354143.</p><p><strong>Results: </strong>A total of 174 studies were included. The pooled prevalence of antibiotic prescribing was 42.1% (95%CI [39.2%, 45.1%]). Subgroup analysis indicated that antibiotic prescribing in primary care have not changed significantly over the past 20years. The prevalence of inappropriate antibiotics prescriptions was 57.6% (95%CI [43.4%, 71.2%]). Patients with higher education levels were less likely to receive antibiotic prescriptions.</p><p><strong>Conclusions: </strong>We observed high prevalence of antibiotic prescribing in primary care, especially in low- and middle-income countries. The prevalence of antibiotic prescription has not declined significantly over the past 20years. Therefore, it is necessary to review current antimicrobial stewardship strategies.</p>","PeriodicalId":7621,"journal":{"name":"American journal of infection control","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2025-08-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144870903","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Joana Zorzal Nodari, Felipe Donateli Gatti, Thiago de Jesus Sousa, Gabriela Colombo de Mendonça, Thabata Coeli Dias Damasceno, Sarah Martins Presti da Silva, Eric Arrivabene Tavares, Suwellen Sardinha Dias de Azevedo, Jaqueline Pegoretti Goulart, Edson Delatorre, Rodrigo Ribeiro-Rodrigues
{"title":"Genomic and epidemiologic investigation of arboviral coinfections, Espírito Santo, Brazil.","authors":"Joana Zorzal Nodari, Felipe Donateli Gatti, Thiago de Jesus Sousa, Gabriela Colombo de Mendonça, Thabata Coeli Dias Damasceno, Sarah Martins Presti da Silva, Eric Arrivabene Tavares, Suwellen Sardinha Dias de Azevedo, Jaqueline Pegoretti Goulart, Edson Delatorre, Rodrigo Ribeiro-Rodrigues","doi":"10.1016/j.ajic.2025.08.008","DOIUrl":"10.1016/j.ajic.2025.08.008","url":null,"abstract":"<p><strong>Background: </strong>In Brazil, the simultaneous circulation of arboviruses is driven by anthropological factors. In places with intense arbovirus transmission, such as Espírito Santo, it is important to investigate the epidemiology of coinfections in order to provide information to improve surveillance and management strategies.</p><p><strong>Methods: </strong>We assessed their prevalence, clinical impact, and viral diversity in Espírito Santo, Brazil (2023-2024), testing 66,019 patients for dengue, chikungunya, Zika, Mayaro, and Oropouche viruses via RT-qPCR and genomic sequencing.</p><p><strong>Results: </strong>Overall, 34.45% tested positive, mainly for OROV (21.93%), DENV (19.57%), and CHIKV (6.94%), while ZIKV and MAYV were undetected. Coinfections were rare (0.2%, n = 44), mostly DENV/CHIKV (75%), with 2 novel DENV-1/DENV-2/CHIKV cases and 1 OROV/DENV-2. Sequencing yielded 12 complete viral genomes, identifying distinct DENV-1, DENV-2, CHIKV, and OROV lineages.</p><p><strong>Discussion: </strong>Genomic characterization of coinfection samples provided a comprehensive view of arboviral genetic diversity, revealing the presence of multiple cocirculating strains. Despite the hyperendemic scenario, coinfections were rare, probably due to complex interactions between viral interference, host immunity, vector behavior and diagnostic challenges.</p><p><strong>Conclusions: </strong>We report the first triple arbovirus infection documented in Espírito Santo and coinfection with OROV outside endemic areas, emphasizing the importance of molecular diagnosis and ongoing research to understand arboviral dynamics and prepare for outbreaks.</p>","PeriodicalId":7621,"journal":{"name":"American journal of infection control","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2025-08-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144870901","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Eugene W Liu, Richelle L Guerrero-Wooley, Anna Y Zhou, James M Pappas
{"title":"Modification of nursing-initiated standing order sets results in a nonsignificant decline in inappropriate urinalyses in an adult emergency department.","authors":"Eugene W Liu, Richelle L Guerrero-Wooley, Anna Y Zhou, James M Pappas","doi":"10.1016/j.ajic.2025.08.007","DOIUrl":"10.1016/j.ajic.2025.08.007","url":null,"abstract":"<p><strong>Background: </strong>Inappropriate treatment of asymptomatic bacteriuria with antimicrobials is widespread in health care facilities and promotes antibiotic resistance. We assessed the degree urinalysis is ordered in absence of urinary symptoms.</p><p><strong>Methods: </strong>We randomly sampled 97 unique patients with urinalyses (UAs) obtained in the Emergency Department in 2022 and reviewed their charts to determine if UAs were ordered according to society guideline-based indications. To identify risk factors for inappropriate ordering, we performed simple logistic regression between patients with inappropriately versus appropriately obtained urinalysis by various demographic factors. Following an intervention where nursing order sets were modified to reflect appropriate urinalysis usage, we reassessed the appropriateness of UAs in a sample of 95 unique patients within 6months postintervention.</p><p><strong>Results: </strong>Preintervention, 65% (95% CI, 54.1%-74.5%) of patients had inappropriately ordered UAs. Postintervention, we noted a nonsignificant decrease to 52% (42.0%-62.4%; χ<sup>2</sup> = 2.8, P = .095) of inappropriately ordered UAs. Postintervention, Hispanic ethnicity was negatively associated with inappropriately obtained UAs (OR 0.30; 0.12-0.71).</p><p><strong>Conclusions: </strong>Most UAs remained inappropriately ordered despite a change in nursing order sets. Our results suggest provider-patient interactions are the major driver of inappropriately obtained UAs. The negative association with inappropriately obtained UAs in Hispanics suggests acuity of disease may influence this interaction.</p>","PeriodicalId":7621,"journal":{"name":"American journal of infection control","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2025-08-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144862011","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Information for Authors","authors":"","doi":"10.1016/S0196-6553(25)00481-X","DOIUrl":"10.1016/S0196-6553(25)00481-X","url":null,"abstract":"","PeriodicalId":7621,"journal":{"name":"American journal of infection control","volume":"53 9","pages":"Pages A10-A11"},"PeriodicalIF":2.4,"publicationDate":"2025-08-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144827918","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Antonino Russotto MD, Roberta Bussolino MD, Costanza Vicentini MD, Carla Maria Zotti PhD
{"title":"Response to “Letter to the editor: Healthcare-associated infections and antimicrobial use---The third point prevalence survey on 42 acute care hospitals in Piedmont, Italy, 2022”","authors":"Antonino Russotto MD, Roberta Bussolino MD, Costanza Vicentini MD, Carla Maria Zotti PhD","doi":"10.1016/j.ajic.2025.05.017","DOIUrl":"10.1016/j.ajic.2025.05.017","url":null,"abstract":"","PeriodicalId":7621,"journal":{"name":"American journal of infection control","volume":"53 9","pages":"Page 1022"},"PeriodicalIF":2.4,"publicationDate":"2025-08-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144827920","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"“Letter to the editor: Health care associated infections and antimicrobial use: The third point prevalence survey on 42 acute care hospitals in Piedmont, Italy, 2022”","authors":"Syed Aaraiz Ul Hassan MBBS , Noor Ul Huda MBBS","doi":"10.1016/j.ajic.2025.05.008","DOIUrl":"10.1016/j.ajic.2025.05.008","url":null,"abstract":"","PeriodicalId":7621,"journal":{"name":"American journal of infection control","volume":"53 9","pages":"Page 1021"},"PeriodicalIF":2.4,"publicationDate":"2025-08-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144827919","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Information for Readers","authors":"","doi":"10.1016/S0196-6553(25)00480-8","DOIUrl":"10.1016/S0196-6553(25)00480-8","url":null,"abstract":"","PeriodicalId":7621,"journal":{"name":"American journal of infection control","volume":"53 9","pages":"Page A8"},"PeriodicalIF":2.4,"publicationDate":"2025-08-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144827917","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}