American journal of infection control最新文献_第8页

APIC's research priorities identified for 2025 and beyond.

IF 3.8 3区医学

American journal of infection control Pub Date : 2025-01-30 DOI: 10.1016/j.ajic.2025.01.019

Sara M Reese, Rebecca Crapanzano-Sigafoos

引用次数: 0

Fluoroquinolone consumption and resistance after an Antibiotic Stewardship Team intervention-An interventional study in a single hospital in Southern Poland from 2018 to 2023.

IF 3.8 3区医学

American journal of infection control Pub Date : 2025-01-30 DOI: 10.1016/j.ajic.2025.01.017

P Serwacki, D A Hareza, M Gajda, W Świątek-Kwapniewska, M Adamowska, K Serwacka, G Zawada, M Wałaszek, J Wójkowska-Mach

{"title":"Fluoroquinolone consumption and resistance after an Antibiotic Stewardship Team intervention-An interventional study in a single hospital in Southern Poland from 2018 to 2023.","authors":"P Serwacki, D A Hareza, M Gajda, W Świątek-Kwapniewska, M Adamowska, K Serwacka, G Zawada, M Wałaszek, J Wójkowska-Mach","doi":"10.1016/j.ajic.2025.01.017","DOIUrl":"10.1016/j.ajic.2025.01.017","url":null,"abstract":"Background: Fluoroquinolones (FQs) are widely used in empiric treatment with progressively rising resistance. Using in-hospital surveillance and following the recommendations of the US Food and Drug Administration and European Medicines Agency, our Antibiotic Stewardship Team(AST) decided to pursue a restrictive policy for FQ utilization. The aim of this study was to evaluate AST intervention restricting FQ use with preauthorization to determine its effectiveness in decreasing consumption and resistance.Methods: This study was conducted in a 650-bed hospital in Poland during 2018 to 2019 and 2022 (preintervention) and 2023 (postintervention). Antibiotic consumption (ABC) and antibiotic resistance were compared for both periods. ABC was expressed as a defined daily doses (DDD) per 1,000 pds, and antibiotic resistance was expressed as a resistance rate parameter to FQ in select gram-negative bacilli.Results: The ABC of all antibiotics varied significantly from 2,987.7 DDD/1,000 pds to 3,741.1 DDD/1,000 pds (2018 vs. 2023). The urology ward showed decreasing FQ consumption from 358.9 DDD/1,000 pds to 43.4 DDD/1,000 pds (from 2018 to 2023, P < .001). A 25% reduction in the resistance rate to FQ was observed, with the greatest difference between 2022 (69.9%) and 2023 (52.6%).Conclusions: This study demonstrates the effectiveness of FQ restriction and preauthorization in a hospital.","PeriodicalId":7621,"journal":{"name":"American journal of infection control","volume":" ","pages":""},"PeriodicalIF":3.8,"publicationDate":"2025-01-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143073318","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Lack of mpox transmission in a long-term care facility despite widespread exposure: Kentucky, 2023.

IF 3.8 3区医学

American journal of infection control Pub Date : 2025-01-26 DOI: 10.1016/j.ajic.2025.01.016

Alexandra Barger, Jennifer Duncan, Dalen Traore, Mattheus Smit, Douglas Thoroughman, Kathleen Winter

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Evaluation of surgical antimicrobial prophylaxis compliance: A multicenter point prevalence study.

IF 3.8 3区医学

American journal of infection control Pub Date : 2025-01-22 DOI: 10.1016/j.ajic.2025.01.014

Yasemin Çakır Kıymaz, Taliha Karakök, Merve Büyükkörük, Barış Manavlı, Cihad Baysal, Muhammed Fatih Karaşın, Merve Türker Işık, Kübra Erbay, Levent Şensoy, Eren Öztürk, Hasan Selçuk Özger, Derya Korkmaz, Sıla Akhan, Alpay Azap

{"title":"Evaluation of surgical antimicrobial prophylaxis compliance: A multicenter point prevalence study.","authors":"Yasemin Çakır Kıymaz, Taliha Karakök, Merve Büyükkörük, Barış Manavlı, Cihad Baysal, Muhammed Fatih Karaşın, Merve Türker Işık, Kübra Erbay, Levent Şensoy, Eren Öztürk, Hasan Selçuk Özger, Derya Korkmaz, Sıla Akhan, Alpay Azap","doi":"10.1016/j.ajic.2025.01.014","DOIUrl":"10.1016/j.ajic.2025.01.014","url":null,"abstract":"Background: This study aimed to determine the frequency of compliance with surgical antimicrobial prophylaxis (SAP) in Turkey and to identify the causes for noncompliance.Methods: This multicenter, prospective, point prevalence study was conducted in 8 hospitals from different regions of Turkey. Patients over 18years who underwent SAP in all hospital surgical units were included. The SAP compliance assessment was carried out under 5 headings: unnecessary prophylaxis, inappropriate drug choice, prolonged prophylaxis, inappropriate dose interval, and inappropriate dosage.Results: The study included 541 patients from 8 centers. About 52.7% (n=285) were female and the median age was 54years (min-max: 18-94). Orthopedics (23.7%) and general surgery (22.2%) were the most common specialties. SAP compliance was 14%. The specialty with the highest rate of inappropriate SAP was orthopedics (97%) and the lowest rate was in ophthalmology (25%). The most common causes of inappropriate SAP were prolonged prophylaxis (92.0%) and inappropriate dose interval (84.6%). Multivariate logistic regression analysis revealed that prolonged surgical time, American Society of Anaesthesiologists (ASA) score 3, and some specialties increased the risk of noncompliance with surgical prophylaxis.Conclusions: This study showed that SAP compliance is low in Turkey and that inappropriateness is caused mostly by prolonged and inappropriate antimicrobial use.","PeriodicalId":7621,"journal":{"name":"American journal of infection control","volume":" ","pages":""},"PeriodicalIF":3.8,"publicationDate":"2025-01-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143035667","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Robotic versus manual disinfection of global priority pathogens at COVID-19-dedicated hospitals.

IF 3.8 3区医学

American journal of infection control Pub Date : 2025-01-21 DOI: 10.1016/j.ajic.2025.01.013

Sayara Bista, Gopiram Syangtan, Kamal Darlami, Arun Bahadur Chand, Shrijana Bista, Mohammad Ataullah Siddiqui, Lok R Pokhrel, Prabin Dawadi, Dev Raj Joshi

{"title":"Robotic versus manual disinfection of global priority pathogens at COVID-19-dedicated hospitals.","authors":"Sayara Bista, Gopiram Syangtan, Kamal Darlami, Arun Bahadur Chand, Shrijana Bista, Mohammad Ataullah Siddiqui, Lok R Pokhrel, Prabin Dawadi, Dev Raj Joshi","doi":"10.1016/j.ajic.2025.01.013","DOIUrl":"10.1016/j.ajic.2025.01.013","url":null,"abstract":"Background: Twelve bacterial families identified as global priority pathogens (GPPs) pose the greatest threat to human health due to declining antibiotic efficacy. Robotics, a swift and contactless tool for disinfecting hospital surfaces, was sought to compare with manual disinfection.Methods: The disinfection efficacy of a robot was compared with manual disinfection for multiple clinical surfaces and inanimate objects at two hospitals in Nepal using bleach (NaOCl). Surfaces were swabbed pre- and post-disinfection and total heterotrophic plate count evaluated, and bacterial pathogens identified using Gram's staining and biochemical characteristics. Disinfection outcomes were reported as log reduction (log10 CFU/inch2) of heterotrophic count and presence or absence of GPPs: Staphylococcus aureus, Escherichia coli, Acinetobacter spp., and Klebsiella pneumoniae, among others.Results: Both robotic and manual disinfection significantly reduced the microbial load (log 2.3 to log 5.8) on hospital surfaces. No pathogens were detected post-disinfection using the robot. Robotic disinfection was more effective, significantly reducing the bacterial load (log 5.8) compared to manual disinfection (log 3.95).Conclusions: Our results showed better efficacy of robotic disinfection over manual disinfection of hospital surfaces, and thus contactless robotic disinfection is recommended for disinfecting surfaces in the hospital and clinical settings as it favors patient safety against GPPs.","PeriodicalId":7621,"journal":{"name":"American journal of infection control","volume":" ","pages":""},"PeriodicalIF":3.8,"publicationDate":"2025-01-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143027873","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Does routine use of sporicidal disinfectants for all postdischarge hospital rooms reduce environmental contamination with Clostridioides difficile spores?

IF 3.8 3区医学

American journal of infection control Pub Date : 2025-01-21 DOI: 10.1016/j.ajic.2025.01.010

Jennifer L Cadnum, Sarah Plumlee, Jennifer M Hailes, Martin Mathew Varghese, Rebecca Crapanzano-Sigafoos, Samir Memic, Annette L Jencson, Curtis J Donskey

引用次数: 0

Infection prevention observations and the expectations of cleaning practices in an assisted reproductive technology (ART)/in vitro fertilization (IVF) clinic: The challenges.

IF 3.8 3区医学

American journal of infection control Pub Date : 2025-01-21 DOI: 10.1016/j.ajic.2025.01.012

Helen Wood, Josephine Fox, Heather Gasama, David K Warren, Misha Foster, Kenan Omurtag, Cindy Barkman, Lydia Grimes-Jenkins

引用次数: 0

Impact of antibiotic treatment and predictors for subsequent infections in multidrug-resistant Pseudomonas aeruginosa catheter-associated asymptomatic bacteriuria.

IF 3.8 3区医学

American journal of infection control Pub Date : 2025-01-21 DOI: 10.1016/j.ajic.2025.01.015

Chisook Moon, Yu Mi Wi

{"title":"Impact of antibiotic treatment and predictors for subsequent infections in multidrug-resistant Pseudomonas aeruginosa catheter-associated asymptomatic bacteriuria.","authors":"Chisook Moon, Yu Mi Wi","doi":"10.1016/j.ajic.2025.01.015","DOIUrl":"10.1016/j.ajic.2025.01.015","url":null,"abstract":"Background: The rate of antibiotic treatment for catheter-associated asymptomatic bacteriuria (CA-ASB) remains high.Methods: We conducted a retrospective study involving hospitalized patients with multidrug-resistant Pseudomonas aeruginosa (MDRP) CA-ASB. Cox proportional hazards regression models were used to identify predictors for subsequent symptomatic infections in patients with MDRP CA-ASB. The probability of remaining free from symptomatic infection was analyzed using Kaplan-Meier curves.Results: The study cohort comprised 139 patients with MDRP CA-ASB. Subsequent symptomatic MDRP infections were observed in 37 (26.6%) patients. Multivariate analysis revealed that underlying urologic diseases (hazard ratio [HR]=2.17, 95% confidence interval [CI]=1.01-4.66, P=.047), active antibiotic treatment for MDRP (HR=2.34, 95% CI=1.02-5.38, P=.046), and recurrent bacteriuria (HR=3.57, 95% CI=1.73-7.38, P=.001) were independent predictors for subsequent symptomatic infections. The Kaplan-Meier analysis demonstrated a significantly lower cumulative proportion of symptomatic infection-free patients among those receiving active antibiotic therapy for MDRP CA-ASB than among those who did not (41.7% vs 76.4%, P=.006, log-rank test).Conclusions: These findings support the current guidelines against routine antibiotic therapy, even for MDRP CA-ASB, and emphasize the need for close monitoring and timely intervention in high-risk populations.","PeriodicalId":7621,"journal":{"name":"American journal of infection control","volume":" ","pages":""},"PeriodicalIF":3.8,"publicationDate":"2025-01-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143027856","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Staffing paradigm for infection prevention and control in the era of antimicrobial resistance: The Veterans Health Administration experience.

IF 3.8 3区医学

American journal of infection control Pub Date : 2025-01-21 DOI: 10.1016/j.ajic.2025.01.011

Linda McKinley, Natalie Hicks, Julie Keating, Carman Fritz, Illa Penavs, Nasia Safdar

引用次数: 0

A review of initial and ongoing training needs through the Alabama Regional Center for Infection Prevention and Control 通过阿拉巴马州感染预防和控制区域中心对初始和正在进行的培训需求的审查。

IF 3.8 3区医学

American journal of infection control Pub Date : 2025-01-19 DOI: 10.1016/j.ajic.2025.01.006

Matthew Fifolt PhD , Elena Kidd MPH , Lisa C. McCormick DrPH, MPH

引用次数: 0