Neuroimage. Reports最新文献

{"title":"A null findings study: graph theoretical analysis of the fetal functional connectome shows no relationships with future autistic traits","authors":"Bosi Chen ,&nbsp;Lanxin Ji ,&nbsp;Iris Menu ,&nbsp;Alexis Taylor ,&nbsp;Christopher J. Trentacosta ,&nbsp;Moriah E. Thomason","doi":"10.1016/j.ynirp.2026.100326","DOIUrl":"10.1016/j.ynirp.2026.100326","url":null,"abstract":"<div><div>Autism spectrum disorder (ASD) is a neurodevelopmental condition, with <em>ex vivo</em> studies suggesting its neurobiological origin as early as the first and second trimester of pregnancy. Functional MRI studies using graph-theoretical approaches have isolated features in the global connectome architecture that distinguish toddlers with ASD from their typically developing peers. Additionally, functional connectivity patterns in the infant brain have shown to be predictive of later ASD diagnosis. An important yet unexplored question in the literature is whether graph-theoretical differences are evident prior to infancy, in the brain of <em>fetuses</em> who will later exhibit ASD traits in early childhood. In this study, we address this question using a sample of 88 children with both quality-assured <em>fetal</em> brain resting-state functional MRI data and standardized parent assessment of ASD traits including social-emotional and social communication skills and repetitive and restricted behaviors at age 3. Multiple regression analyses revealed no significant associations between fetal global graph features (e.g., network segregation, integration, and small-world architecture) and ASD traits at age 3 (<em>p</em>'s &gt; 0.1). Therefore, our findings do not provide support for prenatal emergence of global topographical differences of brain functional organization in fetuses who later develop ASD traits. However, this does not rule out the possibility of other neural signatures in the fetal functional connectome that may predict autistic traits and future ASD diagnosis.</div></div>","PeriodicalId":74277,"journal":{"name":"Neuroimage. Reports","volume":"6 1","pages":"Article 100326"},"PeriodicalIF":0.0,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146214516","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Associations between structural brain alterations and dysfunction across cognitive domains in cerebral small vessel disease: A systematic review and meta-analysis","authors":"Zhijie Zhang ,&nbsp;Xunqi Qian ,&nbsp;Hua Zhang ,&nbsp;Zijun Zhao ,&nbsp;Wei Wang ,&nbsp;Jingpei Wei","doi":"10.1016/j.ynirp.2025.100312","DOIUrl":"10.1016/j.ynirp.2025.100312","url":null,"abstract":"<div><div>Cerebral small vessel disease (CSVD) is a primary contributor to vascular cognitive impairment. Although extensive research has examined white matter alterations in CSVD, cortical mechanisms underlying cognitive dysfunction remain incompletely characterized. To address this gap, we conducted a systematic review and meta-analysis of 26 studies investigating whether structure-cognition relationships in CSVD could be interpreted through biologically defined functional brain networks. By mapping structural features to the Yeo-7 functional atlas, we offer a network-based perspective on cognitive impairment in this population. Our integrated results demonstrate significant associations between structural alterations and all cognitive domains in CSVD patients. Notably, higher-order cognitive processes (e.g., executive function, attention and processing speed) involved more extensive functional networks than other domains. These findings help synthesize heterogeneous neuroanatomical literature on CSVD through contemporary network neuroscience frameworks, suggesting structure-cognition relationships may align with functional network architecture.</div></div>","PeriodicalId":74277,"journal":{"name":"Neuroimage. Reports","volume":"6 1","pages":"Article 100312"},"PeriodicalIF":0.0,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145926500","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Real-time phase-contrast MRI can be used to quantify cerebrovascular reserve capacity – a comparative study to neurovascular ultrasound in healthy subjects","authors":"Christian Horstmann ,&nbsp;Sabine Hofer ,&nbsp;Peter Dechent ,&nbsp;Mathias Bähr ,&nbsp;Ilko Maier","doi":"10.1016/j.ynirp.2026.100332","DOIUrl":"10.1016/j.ynirp.2026.100332","url":null,"abstract":"<div><h3>Background</h3><div>Cerebrovascular reserve capacity (CVRC) is reduced in patients with advanced large artery atherosclerosis (LAA) and represents a risk factor for ischemic stroke. Aim of this study was to compare CVRC testing derived by neurovascular ultrasound (nvUS) and real-time phase-contrast MRI (RT-PC MRI).</div></div><div><h3>Methods</h3><div>In this study 25 subjects (age 33±13 years) without any LAA were first investigated with nvUS followed by RT-PC MRI performing a standardized hyperventilation-apnea-test. CVRC was determined in the medial (MCA) and posterior cerebral artery (PCA) using transtemporal nvUS and RT-PC MRI at 25 fps temporal resolution, 0.8×0.8 mm² in plane resolution and a slice thickness of 6 mm during free breathing. For statistical analysis a paired <em>t</em>-test and a pearson correlation were used at α=0.05.</div></div><div><h3>Results</h3><div>Overall, peak-systolic velocities (PSV) and end-diastolic velocities (EDV) showed lower values for the RT-PC MRI as compared to nvUS. The PSV-decrease during hyperventilation relative to baseline was higher in RT-PC MRI measurements (22% (MCA) and 26% (PCA) for nvUS vs. 34% (MCA) and 39% (PCA) for RT-PC MRI, p&lt;0.001), while the relative PSV-increase from hyperventilation to apnea was comparable between both modalities with a mean difference of &lt;10% (62% (MCA) and 78% (PCA) for nvUS vs. 70% (MCA) and 84% (PCA) for RT-PC MRI, p=0.171 for MCA and p=0.324 for PCA).</div></div><div><h3>Conclusions</h3><div>Both nvUS and RT-PC MRI based CVRC measurements showed reliable de- and increases in PSV during the standardized breathing protocol. RT-PC MRI represents a promising technique to determine CVRC in various intracranial vessels.</div></div>","PeriodicalId":74277,"journal":{"name":"Neuroimage. Reports","volume":"6 1","pages":"Article 100332"},"PeriodicalIF":0.0,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147396377","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Corticomuscular coherence and its non-invasive modulation in stroke applications: a narrative review","authors":"Yuchen Xu ,&nbsp;Shaomin Zhang ,&nbsp;Minmin Wang ,&nbsp;Mohamad Sawan","doi":"10.1016/j.ynirp.2026.100329","DOIUrl":"10.1016/j.ynirp.2026.100329","url":null,"abstract":"<div><div>Neural activities are widely observed in the central nervous system and are essential for movement execution. Corticomuscular coherence (CMC) represents the coherence of oscillatory communication between motor cortex and peripheral muscles. Motor function impairments caused by stroke often involve abnormal CMC patterns. This review aimed to investigate CMC and how to modulate them for post-stroke functional recovery. We first introduced the origins of CMC in movement execution. We then explored how stroke affects CMC. Based on these abnormal CMC patterns, we summarized potential non-invasive neuromodulation strategies. A deeper understanding of CMC in beta band (∼15-30 Hz) could clarify the physiological mechanisms underlying movement and aid in improving stroke rehabilitation.</div></div>","PeriodicalId":74277,"journal":{"name":"Neuroimage. Reports","volume":"6 1","pages":"Article 100329"},"PeriodicalIF":0.0,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147328441","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Case report: Hemodynamic dynamics in central variant PRES via serial ASL/DTI","authors":"Xueping Lu ,&nbsp;Kai Tang ,&nbsp;Qiao Wang ,&nbsp;Wenyu Wang ,&nbsp;Xinling Xie ,&nbsp;Changqing Zhan","doi":"10.1016/j.ynirp.2026.100334","DOIUrl":"10.1016/j.ynirp.2026.100334","url":null,"abstract":"<div><h3>Background</h3><div>Central variant posterior reversible encephalopathy syndrome (PRES) is a rare subtype (4% of cases) affecting brainstem and deep structures, presenting with severe hypertension but minimal neurological deficits, creating diagnostic challenges.</div></div><div><h3>Case presentation</h3><div>A 34-year-old man presented with a two-month history of severe, refractory headache and malignant hypertension (256/150 mmHg). Brain MRI revealed diffuse T2-weighted and FLAIR hyperintensity in the pons and right middle cerebellar peduncle (MCP). Using serial arterial spin labeling (ASL) and diffusion tensor imaging (DTI), we provide the first longitudinal evidence of acute-phase biphasic hemodynamics in central variant PRES: concurrent pontine CBF of 27.1 mL/100 g/min (contralateral reference: 25.2 ± 1.8 mL/100 g/min) and right MCP CBF of 29.3 mL/100 g/min (contralateral reference: 39.1 ± 2.1 mL/100 g/min). This regional perfusion imbalance is consistent with autoregulatory failure and blood-brain barrier (BBB) compromise, leading to vasogenic edema. Critically, the coexistence of these opposing patterns reveals complementary hemodynamic phenotypes of cerebrovascular dysregulation. Post-treatment, pontine CBF was 25.3 mL/100 g/min (contralateral reference: 25.3 ± 1.8 mL/100 g/min) and right MCP CBF was 38.6 mL/100 g/min (contralateral reference: 39.2 ± 2.2 mL/100 g/min), both within the reference range of the contralateral regions, accompanied by progressive increase of fractional anisotropy (FA) on DTI at both the 6-day and 90-day follow-up imaging time points.</div></div><div><h3>Conclusion</h3><div>This case demonstrates biphasic hemodynamic changes in central variant PRES, supporting autoregulatory failure as the mechanism. Serial ASL/DTI provide valuable biomarkers for monitoring recovery in this rare phenotype.</div></div>","PeriodicalId":74277,"journal":{"name":"Neuroimage. Reports","volume":"6 1","pages":"Article 100334"},"PeriodicalIF":0.0,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147380020","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The critical role of the basal ganglia in post-stroke fatigue: A pilot study","authors":"Olga Boukrina ,&nbsp;John DeLuca ,&nbsp;Glenn R. Wylie","doi":"10.1016/j.ynirp.2025.100313","DOIUrl":"10.1016/j.ynirp.2025.100313","url":null,"abstract":"<div><div>This pilot study aimed to explore the neural mechanisms underlying cognitive fatigue (CF) in stroke survivors, with a focus on the role of basal ganglia damage. Sixteen participants were recruited, including six stroke survivors with basal ganglia lesions (BG+), four with lesions elsewhere in the brain (BG−), and six healthy controls (HC). Participants underwent neuropsychological assessments and an fMRI fatigue induction task, where CF was induced using a modified letter-comparison task under individually titrated response deadlines. CF was assessed using the Visual Analog Scale of Fatigue (VAS-F), and fMRI data were analyzed to identify task-evoked activation within the fatigue network. Stroke survivors reported higher levels of CF compared to healthy controls, with the BG+ group exhibiting the highest fatigue levels and the greatest increase in fatigue over time. The BG+ group also demonstrated the most pronounced disparity in reaction times between short and long response deadlines. Functional neuroimaging revealed that CF ratings correlated with task-evoked activation in the fatigue network, but only in the BG− group. Our findings suggest that while stroke presence generally may increase CF, damage specifically involving the basal ganglia accelerates its accrual. Moreover, the ability to engage the fatigue network may mitigate fatigue, as observed in the BG− group. These results underscore the importance of basal ganglia in understanding CF and highlight the need for future research in this area.</div></div>","PeriodicalId":74277,"journal":{"name":"Neuroimage. Reports","volume":"6 1","pages":"Article 100313"},"PeriodicalIF":0.0,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145791806","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cerebral plasticity after hypoglosso-facial anastomosis in facial palsy: a magnetoencephalography study","authors":"Rémi Hervochon ,&nbsp;Deborah Ziri ,&nbsp;Guillaume Dupuch ,&nbsp;Maximilien Chaumon ,&nbsp;Claire Foirest ,&nbsp;Denis Schwartz ,&nbsp;Christophe Gitton ,&nbsp;Nathalie George ,&nbsp;Frédéric Tankere","doi":"10.1016/j.ynirp.2025.100294","DOIUrl":"10.1016/j.ynirp.2025.100294","url":null,"abstract":"<div><h3>Background</h3><div>Hypoglosso-facial anastomosis (HFA) consists in suturing the proximal part of the hypoglossal nerve with the distal part of the facial nerve in patients with facial palsy. Axonal regrowth through the anastomosis makes it possible to restore facial motor skills, which become spontaneous after physiotherapy. This suggests cerebral plasticity.</div></div><div><h3>Objective</h3><div>We used magnetoencephalography (MEG) in a pilot study to test this hypothesis.</div></div><div><h3>Methods</h3><div>Twenty-one healthy volunteers (CTRL) and 12 patients after HFA performed 5 motor tasks with MEG and electromyographic recordings: eyelid closure, smile, tongue protraction, mastication and thumb flexion. For each task, we picked the location of the maximum source activity within the precentral gyrus. We calculated the distances between this location and the vertex for each task and a somatotopy index.</div></div><div><h3>Results</h3><div>There was an interaction between the participant’s group and the task (F(4,124) = 4.07, p = 0.0039). In CTRL, the maximum source location was statistically different between smile and tongue tasks and between eyelid and tongue tasks (p &lt; 0.001). No such difference was observed in HFA (p = 1.000). 90.5 % of CTRL and 41.7 % of HFA showed a normal somatotopy (p = 0.0046).</div></div><div><h3>Conclusions</h3><div>In CTRL, the organization of the cortical motor areas was similar to that of Penfield’s motor Homunculus. In contrast, in HFA, eyelid closure, tongue protraction and smile areas were not significantly distinct. This supports the hypothesis of cerebral plasticity after HFA.</div><div>The Ethical Committee of Paris Idf VI approved the study (CPP Ouest 6-CPP975-HPS2).</div></div>","PeriodicalId":74277,"journal":{"name":"Neuroimage. Reports","volume":"5 4","pages":"Article 100294"},"PeriodicalIF":0.0,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145226912","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Temporally parallel facilitation of same-colored objects beyond spatial selection","authors":"S. Wehle,&nbsp;C. Gundlach,&nbsp;M.M. Müller","doi":"10.1016/j.ynirp.2025.100302","DOIUrl":"10.1016/j.ynirp.2025.100302","url":null,"abstract":"<div><div>In a probabilistic spatial cueing experiment, we cued one out of four objects/arcs that were arranged in a circle to test whether the cued arc/object would result in strictly object-based processing restricting facilitation of features to the cued object, or whether we observe global feature-based spread across object boundaries. Four arcs flickered at different frequencies, respectively, to evoke steady state visual evoked potentials (SSVEPs), allowing to investigate neural temporal dynamics in the early visual cortex following the presentation of the spatial cue. Initially, all arcs had identical colors and with spatial cue onset switched to a specific color configuration. In one configuration, one uncued arc had the same color as the cued one. We found global feature-based spread to same-colored elements across object boundaries in SSVEPs and behavioral responses. Once spatial attention was shifted to the cued location/arc, SSVEP amplitudes elicited by the cued arc and the same-colored uncued arc showed a temporally overlapping increase early after the spatial cue. Importantly, color processing was not required to perform the task, indicating that global feature-based spread occurs automatically, independent of task demands.</div></div>","PeriodicalId":74277,"journal":{"name":"Neuroimage. Reports","volume":"5 4","pages":"Article 100302"},"PeriodicalIF":0.0,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145623884","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Altered white matter connection from the locus coeruleus to the thalamus in Parkinson's disease","authors":"M.G. Wanders ,&nbsp;J.F.A. Jansen ,&nbsp;A.F. Wolters ,&nbsp;M. Heijmans ,&nbsp;Y. Temel ,&nbsp;M.L. Kuijf ,&nbsp;S.M.A. Michielse","doi":"10.1016/j.ynirp.2025.100292","DOIUrl":"10.1016/j.ynirp.2025.100292","url":null,"abstract":"<div><h3>Background</h3><div>Parkinson's disease (PD) is the fastest growing neurodegenerative movement disorder. It is characterized by both motor and non-motor, including neuropsychiatric disturbances such as depression and anxiety. The locus coeruleus (LC), a small nucleus in the brainstem, plays a key role in these symptoms and has white matter connections to the thalamus. This study aims to investigate this LC-thalamic tract in PD patients using ultra-high-field diffusion-weighted imaging (DWI) and to examine its relationship with non-motor symptoms.</div></div><div><h3>Methods</h3><div>100 participants, including 69 early-stage PD and 31 healthy control (HC) participants were evaluated using several questionnaires and a 7T diffusion MRI scan. Tractography was performed to reconstruct the LC-thalamic white matter tract, and diffusion parameters (FA, MD, AD, RD) were analysed.</div></div><div><h3>Results</h3><div>PD patients showed significantly higher mean diffusivity (MD) and axial diffusivity (AD) in the white matter tissue compared to HC, indicating reduced white matter integrity.</div></div><div><h3>Discussion</h3><div>This study shows the feasibility to visualize the LC-thalamic tract with the use of 7T DWI data. The results provide evidence of the association between the integrity of the white matter tracts and early PD development, highlighting its potential as a target for therapeutic interventions. Further research is needed to elucidate the role of the LC and its white matter connections in the progression of PD and neuropsychiatric and other symptoms.</div></div>","PeriodicalId":74277,"journal":{"name":"Neuroimage. Reports","volume":"5 4","pages":"Article 100292"},"PeriodicalIF":0.0,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145159813","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Resting-state functional connectivity changes in the human brain from electrically-stimulated (2 Hz), rhythmic muscle contractions to the hand: An exploratory study","authors":"William T. Stauber ,&nbsp;Tyler McGaughey ,&nbsp;Nick Evans ,&nbsp;Sean Snyder ,&nbsp;Julie A. Brefczynski-Lewis ,&nbsp;James W. Lewis","doi":"10.1016/j.ynirp.2025.100303","DOIUrl":"10.1016/j.ynirp.2025.100303","url":null,"abstract":"<div><div>Sensory nerves from contracting skeletal muscles can alter autonomic functions mediated by connections in the medulla and hypothalamus. We hypothesized that low-frequency, non-voluntary, rhythmical electrical stimulation of small muscles of the hand, in contrast to continuous sensory stimulation of the overlying skin, will change functional connectivity in the brain revealing specific regions of the muscle afferent–pituitary axis. Using a 2x2 design, eight healthy young participants underwent resting-state functional magnetic resonance imaging (rsfMRI) immediately before and after a 45-min electrical stimulation session with 2 Hz to the left hand muscles and a counterbalanced session with continuous 100 Hz skin stimulation to the same region. Using standardized CONN toolbox software, functional connectivity data were analyzed. Rhythmic muscle stimulation led to significant differences in connectivity associated with the autonomic and limbic systems such as the hypothalamus, amygdala, periaqueductal gray, thalamus, basal ganglia, plus insulae and cingulate cortices. In addition, the muscle stimulation led to changes in several resting state networks. Importantly, using a tightly controlled 2x2 rsfMRI design, the different stimulation protocols were applied to each subject (within-subject design), which led to significant differences in patterns of functional connectivity changes after the muscle versus skin stimulation conditions with only a small number of participants. In conclusion, significant differences in brain networks involving autonomic and limbic systems were activated by using low-frequency, rhythmical stimulation of small hand muscles. In contrast to skin electrical stimulation, which primarily entailed exteroceptive input, muscle electrical stimulation significantly engaged neural networks implicated in interoception, including the insula and hypothalamus.</div></div>","PeriodicalId":74277,"journal":{"name":"Neuroimage. Reports","volume":"5 4","pages":"Article 100303"},"PeriodicalIF":0.0,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145693448","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}