Advances in Nutrition最新文献

{"title":"Riboflavin","authors":"John Thomas Pinto, Lora A Sporny","doi":"10.1016/j.advnut.2026.100649","DOIUrl":"10.1016/j.advnut.2026.100649","url":null,"abstract":"","PeriodicalId":7349,"journal":{"name":"Advances in Nutrition","volume":"17 6","pages":"Article 100649"},"PeriodicalIF":12.7,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147935920","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Dietary Supplement Bioactives: When Rigorous Frameworks Meet Regulatory Uncertainty","authors":"Kevin C Klatt","doi":"10.1016/j.advnut.2026.100635","DOIUrl":"10.1016/j.advnut.2026.100635","url":null,"abstract":"","PeriodicalId":7349,"journal":{"name":"Advances in Nutrition","volume":"17 6","pages":"Article 100635"},"PeriodicalIF":12.7,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148260665","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Vitamin D Fortification of Dairy Products in the United Kingdom: What Are the Barriers?","authors":"Cheuk Lun Wong ,&nbsp;D Ian Givens ,&nbsp;Daniele Asioli ,&nbsp;Anu M Turpeinen ,&nbsp;Jia Han ,&nbsp;L Kirsty Pourshahidi ,&nbsp;Jing Guo","doi":"10.1016/j.advnut.2026.100645","DOIUrl":"10.1016/j.advnut.2026.100645","url":null,"abstract":"<div><div>Given the inadequate vitamin D intake and status in the United Kingdom population, the Scientific Advisory Committee on Nutrition recognized the difficulty of achieving a reference nutrient intake of vitamin D (10 μg/d) simply from natural food sources. Therefore, additional food vehicles for vitamin D fortification are needed to improve vitamin D intake and status. Dairy products represent a potential vehicle for fortification, given their status as staple foods in the United Kingdom. In recent workshops (October 2024 and March 2025), barriers to vitamin D fortification of dairy products were discussed by a group of experts. The main conclusions from the workshops are presented in this review and position paper and are as follows: <em>1</em>) there is convincing evidence of the need to improve vitamin D status. <em>2</em>) Furthermore, evidence is required including modeling studies to examine a wide variety of dairy products potentially being fortified using the United Kingdom population data, especially those who are at risk of vitamin D deficiency such as children and young female populations, as well as cost evaluation studies of vitamin D fortification. <em>3</em>) More research on consumer preferences toward vitamin D-fortified dairy products is needed. <em>4</em>) Vitamin D fortification of dairy products may not be technically difficult, but it may involve additional cost for dairy food manufacturers, such as purchasing specific equipment for vitamin D addition. <em>5</em>) The retailing and promotion of vitamin D-fortified dairy products are influenced by various factors such as price and customer perceptions. This review further: <em>1</em>) highlights the barriers to the promotion and legislation of mandatory vitamin D fortification policy of dairy products, <em>2</em>) reviews current evidence of each barrier, and <em>3</em>) identifies research gaps that need to be addressed in the future.</div></div>","PeriodicalId":7349,"journal":{"name":"Advances in Nutrition","volume":"17 6","pages":"Article 100645"},"PeriodicalIF":9.2,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147846794","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Flavonoids","authors":"Alex Cheok,&nbsp;Ana Rodriguez-Mateos","doi":"10.1016/j.advnut.2026.100611","DOIUrl":"10.1016/j.advnut.2026.100611","url":null,"abstract":"","PeriodicalId":7349,"journal":{"name":"Advances in Nutrition","volume":"17 5","pages":"Article 100611"},"PeriodicalIF":9.2,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147367363","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Nutritional Needs, Dietary Knowledge, and Culinary Skills in Individuals with Diabetes Mellitus: A Scoping Review","authors":"Jorge Casaña Mohedo ,&nbsp;María Teresa Murillo-Llorente ,&nbsp;Alma Palau Ferre ,&nbsp;María Faus ,&nbsp;Barbara Gómez Taylor ,&nbsp;Francisca Esteve Claramunt ,&nbsp;Sara Morales Palomares ,&nbsp;Elena Sandri","doi":"10.1016/j.advnut.2026.100627","DOIUrl":"10.1016/j.advnut.2026.100627","url":null,"abstract":"<div><div>Dietary management is a cornerstone of diabetes mellitus (DM) care. However, a persistent disconnect remains between theoretical nutritional knowledge, what individuals are advised to eat, and the practical culinary skills required to translate these recommendations into daily practice. This gap is frequently compounded by socioeconomic constraints and cultural determinants. To map the available evidence on dietary knowledge, culinary skills, and food-related practices among people with DM, with particular attention to barriers and facilitators in daily-life settings. A scoping review was conducted following the Joanna Briggs Institute methodology and Preferred Reporting Items for Systematic Reviews and Meta-Analyses for scoping reviews guidelines. Major databases (MEDLINE/PubMed, Scopus, Web of Science, and Embase) were searched for studies published between 2014 and 2025. Extracted variables were mapped deductively to the World Health Organization International Classification of Functioning, Disability and Health, distinguishing self-care and dietary management (d5) from domestic-life competencies related to meal preparation (d6). Forty-six studies were included. The evidence base was heterogeneous and focused largely on dietary self-management, whereas comparatively few studies explicitly assessed instrumental cooking skills (<em>n</em> = 8). Across studies, structural barriers, particularly food insecurity and the cost and availability of healthier foods, frequently limited the feasibility of recommended diets. Skills-based interventions, including culinary medicine and hands-on cooking programs, were associated with improvements in culinary self-efficacy and, in some studies, clinically meaningful hemoglobin A1c reductions. Family dynamics, peer support, and culturally shaped practices (including religious observances) emerged as important determinants of adherence. Current diabetes education strategies risk achieving conceptual adequacy without practical applicability. Effective dietary management in DM requires a shift from predominantly prescriptive nutritional advice toward skills-based approaches grounded in culinary medicine. Future interventions should be culturally responsive and explicitly address environmental and social barriers to bridge the gap between clinical recommendations and real-world implementation.</div><div>This systematic review followed a protocol registered prospectively on Open Science Framework available at: <span><span>https://doi.org/10.17605/OSF.IO/J9PHQ</span><svg><path></path></svg></span>.</div></div>","PeriodicalId":7349,"journal":{"name":"Advances in Nutrition","volume":"17 5","pages":"Article 100627"},"PeriodicalIF":9.2,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147640704","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Nutrition 2026 – Join The Global Nutrition Community in Washington D.C. (USA), July 25-28","authors":"","doi":"10.1016/S2161-8313(26)00070-0","DOIUrl":"10.1016/S2161-8313(26)00070-0","url":null,"abstract":"","PeriodicalId":7349,"journal":{"name":"Advances in Nutrition","volume":"17 5","pages":"Article 100656"},"PeriodicalIF":9.2,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147950976","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Bioavailability of and US Infant Exposure to Arsenic, Cadmium, Lead, Mercury, and Per- and Polyfluoroalkyls from Human Milk and Infant Formula: Results from a Series of Systematic Reviews","authors":"Lauren E O’Connor ,&nbsp;Rachel C Thoerig ,&nbsp;Cassi N Leta ,&nbsp;Arin A Balalian ,&nbsp;Shailesh M Advani ,&nbsp;Trish Bosse ,&nbsp;Margaret J Foster ,&nbsp;Kyle M Holland ,&nbsp;Kathryn G Dewey ,&nbsp;Mandy M Fisher ,&nbsp;Aubrey L Galusha ,&nbsp;Carin A Huset ,&nbsp;Amanda J MacFarlane ,&nbsp;Maureen K Spill","doi":"10.1016/j.advnut.2026.100628","DOIUrl":"10.1016/j.advnut.2026.100628","url":null,"abstract":"<div><div>Infants may be exposed to contaminants from environmental and food sources, including human milk (HM) or infant formula (IF). The objective of this series of systematic reviews (PROSPERO: CRD42024530332, CRD42024530336, CRD42024530339, and CRD42024530344) was to <em>1</em>) assess infant exposure to contaminants from HM and/or IF in the United States and <em>2</em>) assess the bioavailability of these contaminants from HM and IF when consumed by infants. The protocol was developed with a technical expert panel (TEP). Through 2 April, 2025, CAB Abstracts, CENTRAL, CINAHL, Embase, and MEDLINE databases were searched for peer-reviewed articles published in English. Another TEP critically appraised sample collection and contaminant assessment methods for included articles. Studies needed to report contaminant concentrations of biospecimens based on infant feeding (HM only, IF only, or HM and IF). Results were narratively described. Risk of bias was assessed using ROBINS-E. From 6799 unique records, 7 articles from 4 studies were identified. The New Hampshire birth cohort reported infant urinary concentrations of arsenic (<em>n</em> = 4 articles), cadmium (<em>n</em> = 2), lead (<em>n</em> = 1), and mercury (<em>n</em> = 1) between 2009 and 2019. Three other studies reported infant blood lead concentrations between 1975 and 1994. All articles had acceptable contaminant assessment methods, and most (<em>n</em> = 6 articles) had low risk or some concerns of bias. Collectively, most evidence was from 1 cohort or published 30+ y ago and lacked demographic and geographic diversity. Therefore, conclusions could not be made about exposure to arsenic, cadmium, lead, or mercury from HM and/or IF for infants in the United States. No evidence was found that reported on per- and polyfluoroalkyl substances in infant biospecimens or bioavailability of any of the contaminants from HM or IF. These findings highlight the need for research about infant exposure to and bioavailability of arsenic, cadmium, lead, mercury, and per- and polyfluoroalkyl substances from HM or IF in the United States.</div></div>","PeriodicalId":7349,"journal":{"name":"Advances in Nutrition","volume":"17 5","pages":"Article 100628"},"PeriodicalIF":9.2,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147663253","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Leveraging Multiomic Signatures to Predict Body Composition","authors":"Sri Lakshmi S Devarakonda ,&nbsp;David A Hughes ,&nbsp;Christian Rodriguez ,&nbsp;Marcus D Goncalves ,&nbsp;Steven B Heymsfield","doi":"10.1016/j.advnut.2026.100626","DOIUrl":"10.1016/j.advnut.2026.100626","url":null,"abstract":"<div><div>Obesity, sarcopenia, malnutrition, and cachexia all include assessment of body composition in their respective clinical guidelines, although patient evaluations frequently require hardware that may not be available. Body mass index often fills this void, but its accuracy as a body composition phenotyping method is limited. Recent advances suggest a new option for assessing patient body composition: omics-derived circulating blood biomarkers applied in combination with demographic information or alone to estimate the mass or volume of clinically relevant body components. The origin of this movement has its roots, among other factors, in 2 longstanding observations: that serum concentrations of the metabolite creatinine are associated with total body skeletal muscle mass and that serum concentrations of the protein leptin are associated with total body adipose tissue mass. The first section of this review demonstrates how body composition prediction models can be developed that exploit these kinds of observations by adding serum metabolite and protein measurements to conventional equations designed to estimate components that include demographic covariates such as weight, height, sex, and body circumferences. The second section of this review then broadens the number of potential circulating blood metabolites and proteins examined by reviewing advances in omics technology that offer the potential to improve conventional body composition prediction models that include demographic data or to create models solely based on blood biomarker measurements. The final section of the review presents a perspective on this rapidly advancing area of human body composition assessment.</div></div>","PeriodicalId":7349,"journal":{"name":"Advances in Nutrition","volume":"17 5","pages":"Article 100626"},"PeriodicalIF":9.2,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147624780","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Charting a New Era to Modernize United States Infant Formula Regulation","authors":"Douglas G Burrin ,&nbsp;Amy B Hair ,&nbsp;Sharon M Donovan","doi":"10.1016/j.advnut.2026.100606","DOIUrl":"10.1016/j.advnut.2026.100606","url":null,"abstract":"","PeriodicalId":7349,"journal":{"name":"Advances in Nutrition","volume":"17 4","pages":"Article 100606"},"PeriodicalIF":9.2,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146208430","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Guiding Principles for Science-Based Food Classification Systems Focused on Processing and Formulation","authors":"Jodi T Bernstein ,&nbsp;Andrew W Brown ,&nbsp;Britt Burton-Freeman ,&nbsp;Mario Estevez ,&nbsp;Julie M Hess ,&nbsp;Patrice A Hubert ,&nbsp;Marie E Latulippe","doi":"10.1016/j.advnut.2025.100577","DOIUrl":"10.1016/j.advnut.2025.100577","url":null,"abstract":"<div><div>Food classification systems that focus on food formulation &amp; processing classification (FF&amp;PC systems) have gained traction in research and dietary policies. Yet, their utility and scientific foundations are debated. To address criticisms and identify paths forward, the Institute for the Advancement of Food and Nutrition Sciences convened a Working Group comprising government, industry, and academic scientists to conceptualize a project to meet the needs of the scientific community in addressing recurring concerns about FF&amp;PC systems in the literature. Born from this, an independent public sector Writing Team with expertise in food science, nutrition research and methodology, dietary guidance, and sensory science led the development of guiding principles for researchers to consider when developing, refining, and applying FF&amp;PC systems for public health. The principles emphasize the need for transparent documentation; distinguishable versioning; strong, and ideally causal, evidence of a putative effect of specific processing steps and formulation components with health-related endpoints; evolution over time in response to scientific advances and changes to the food supply; and consideration of current scientific consensus, validation contexts, and the probative value of research questions and new FF&amp;PC systems. These principles are intended to provide a shared foundation and standardized approach to guide researchers in this area without endorsing or advocating for the creation or use of FF&amp;PC systems. These aspirational principles can be used to identify future research priorities and areas for investment while also providing guidance on cautionary action in the absence of complete data. Adherence to these principles is also intended to limit the continued expenditure of resources critiquing or defending new FF&amp;PC systems. These principles can serve as a foundation to support impactful research on FF&amp;PC systems and, through this, public health policy.</div></div>","PeriodicalId":7349,"journal":{"name":"Advances in Nutrition","volume":"17 4","pages":"Article 100577"},"PeriodicalIF":9.2,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147710400","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}