Advances in Nutrition最新文献

{"title":"The Role of Iron in Intestinal Mucus: Perspectives from Both the Host and Gut Microbiota","authors":"Shuan Liu ,&nbsp;Jie Yin ,&nbsp;Dan Wan ,&nbsp;Yulong Yin","doi":"10.1016/j.advnut.2024.100307","DOIUrl":"10.1016/j.advnut.2024.100307","url":null,"abstract":"<div><div>Although research on the role of iron in host immunity has a history spanning decades, it is only relatively recently that attention has been directed toward the biological effects of iron on the intestinal mucus layer, prompted by an evolving understanding of the role of this material in immune defense. The mucus layer, secreted by intestinal goblet cells, covers the intestinal epithelium, and given its unique location, interactions between the host and gut microbiota, as well as among constituent microbiota, occur frequently within the mucus layer. Iron, as an essential nutrient for the vast majority of life forms, regulates immune responses from both the host and microbial perspectives. In this review, we summarize the iron metabolism of both the host and gut microbiota and describe how iron contributes to intestinal mucosal homeostasis via the intestinal mucus layer with respect to both host and constituent gut microbiota. The findings described herein offer a new perspective on iron-mediated intestinal mucosal barrier function.</div></div>","PeriodicalId":7349,"journal":{"name":"Advances in Nutrition","volume":"15 11","pages":"Article 100307"},"PeriodicalIF":8.0,"publicationDate":"2024-09-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142333479","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Narrative Review of Strategies to Optimize Nutrition, Feeding, and Growth among Preterm-Born Infants: Implications for Practice","authors":"Faith E Bala ,&nbsp;Katlyn E McGrattan ,&nbsp;Christina J Valentine ,&nbsp;Sudarshan R Jadcherla","doi":"10.1016/j.advnut.2024.100305","DOIUrl":"10.1016/j.advnut.2024.100305","url":null,"abstract":"<div><div>Preterm birth is the leading cause of neonatal and under-5 mortality globally, and healthcare-related burden and nutrition-related morbidities are unsustainable, particularly in resource-limited regions. Additionally, preterm infants are susceptible to multiple adverse outcomes including growth faltering, suboptimal neurodevelopment, and multisystemic morbidities. Maturation, healing, repair, and restoration to normalcy in preterm-born infants require optimizing nutrition; only then, prognosis, growth, neurodevelopment, and overall quality of life can improve. In this article, we discuss the various evidence-based feeding and nutritional strategies that can be applicable even in resource-limited settings, where resources and infrastructure for advanced neonatal care are limited. This article addresses nutrition, feeding strategies, and growth monitoring in the neonatal intensive care unit and at discharge to optimize nutrition, growth, and development.</div></div>","PeriodicalId":7349,"journal":{"name":"Advances in Nutrition","volume":"15 11","pages":"Article 100305"},"PeriodicalIF":8.0,"publicationDate":"2024-09-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142309225","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Carotenoids","authors":"Abdulkerim Eroglu ,&nbsp;Genan Wang ,&nbsp;Nathan Crook ,&nbsp;Torsten Bohn","doi":"10.1016/j.advnut.2024.100304","DOIUrl":"10.1016/j.advnut.2024.100304","url":null,"abstract":"","PeriodicalId":7349,"journal":{"name":"Advances in Nutrition","volume":"15 11","pages":"Article 100304"},"PeriodicalIF":8.0,"publicationDate":"2024-09-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142302209","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Addressing Infant and Young Child Feeding Recommendations From a Planetary Health Perspective","authors":"Andrea Santos-Guzmán ,&nbsp;Juan A Rivera ,&nbsp;Mishel Unar-Munguía ,&nbsp;Ivonne Ramírez-Silva","doi":"10.1016/j.advnut.2024.100303","DOIUrl":"10.1016/j.advnut.2024.100303","url":null,"abstract":"<div><div>Current international infant and young child (IYC) feeding recommendations consider nutrition and health but not environmental impacts. Only a handful of countries have dietary guidelines that provide quantitative recommendations for food groups of environmental concern. This study aimed to perform a narrative review of the environmental impacts of commercial milk formula compared with breastfeeding and to analyze the degree to which current country-specific IYC feeding recommendations are aligned with sustainable dietary targets. A mixed-methods review was conducted, including the following: <em>1</em>) a narrative review of the environmental impact of commercial milk formula compared with breastfeeding and <em>2</em>) a comparison of recommended intake of meats and dairy for children IYC based on country-specific dietary guidelines compared with the EAT–Lancet Commission dietary targets (ELCT) for children 24 mo or older and adults and if the ELCT should be adjusted for the energy needs of IYC. Formula feeding has a greater environmental impact (∼48% higher carbon footprint) than exclusive breastfeeding. Available country-specific dietary guidelines for meat and dairy products in children IYC are, in general, at or below the upper limits of the ELCT recommended ranges for older children and adults but are in most cases above the upper limit when adjusting for the energy needs of IYC. Exclusive breastfeeding should be protected and promoted not only as the healthier but also as the most sustainable alternative. Available complementary dietary feeding recommendations of nonprocessed meat and dairy fall below current ELCT for older children and adults. Given that IYC require a more nutrient-dense diet than older children and adults and considering the small quantities they consume, we recommend using the unadjusted ELCT as reference for IYC feeding while specific international consumption recommendations are developed for this age group.</div></div>","PeriodicalId":7349,"journal":{"name":"Advances in Nutrition","volume":"15 11","pages":"Article 100303"},"PeriodicalIF":8.0,"publicationDate":"2024-09-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142302208","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Carbon Isotope Ratio as an Objective Biomarker of Added Sugar Intake: A Scoping Review of Current Evidence in Human Nutrition","authors":"Gina L Tripicchio ,&nbsp;Alissa D Smethers ,&nbsp;Jessica J Johnson ,&nbsp;Jordan A Olenginski ,&nbsp;Diane M O’Brien ,&nbsp;Jennifer Orlet Fisher ,&nbsp;Vitalina A Robinson ,&nbsp;Sarah H Nash","doi":"10.1016/j.advnut.2024.100281","DOIUrl":"10.1016/j.advnut.2024.100281","url":null,"abstract":"<div><p>Objective biomarkers of dietary intake are needed to advance nutrition research. The carbon isotope ratio (C¹³/C¹²; CIR) holds promise as an objective biomarker of added sugar (AS) and sugar-sweetened beverage (SSB) intake. This systematic scoping review presents the current evidence on CIRs from human studies. Search results (through April 12, 2024) yielded 6297 studies and 24 final articles. Studies were observational (<em>n</em> = 12), controlled feeding (<em>n</em> = 10), or dietary interventions (<em>n</em> = 2). CIRs were sampled from blood (<em>n</em> = 23), hair (<em>n</em> = 5), breath (<em>n</em> = 2), and/or adipose tissue (<em>n</em> = 1). Most (<em>n</em> = 17) conducted whole tissue (that is, bulk) analysis, 8 used compound specific isotope analysis (CSIA), and/or 2 studies used methods appropriate for analyzing breath. Studies were conducted in 3 concentrated geographic regions of the United States (<em>n</em> = 7 Virginia; <em>n</em> = 5 Arizona; <em>n</em> = 4 Alaska), with only 2 studies conducted in other countries. Studies that used CSIA to examine the CIR from the amino acid alanine (CIR-Ala; <em>n</em> = 4) and CIR analyzed from breath (<em>n</em> = 2) provided the most robust evidence for CIR as an objective biomarker of AS and SSBs (<em>R</em>² range 0.36–0.91). Studies using bulk analysis of hair or blood showed positive, but modest and more variable associations with AS and SSBs (<em>R</em>² range 0.05–0.48). Few studies showed no association, particularly in non-United States populations and those with low AS and SSB intakes. Two studies provided evidence for CIR to detect changes in SSB intake in response to dietary interventions. Overall, the most compelling evidence supports CIR-Ala as an objective indicator of AS intake and breath CIR as an indicator of short-term AS intake. Considering how to adjust for underlying dietary patterns remains an important area of future work and emerging methods using breath and CSIA warrant additional investigation. More evidence is needed to refine the utility and specificity of CIRs to measure AS and SSB intake.</p></div>","PeriodicalId":7349,"journal":{"name":"Advances in Nutrition","volume":"15 9","pages":"Article 100281"},"PeriodicalIF":8.0,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2161831324001157/pdfft?md5=3ee75ff60a5fc2c1436520b795265149&pid=1-s2.0-S2161831324001157-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141879934","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Artificial Intelligence in Malnutrition: A Systematic Literature Review","authors":"","doi":"10.1016/j.advnut.2024.100264","DOIUrl":"10.1016/j.advnut.2024.100264","url":null,"abstract":"<div><p>Malnutrition among the population of the world is a frequent yet underdiagnosed problem in both children and adults. Development of malnutrition screening and diagnostic tools for early detection of malnutrition is necessary to prevent long-term complications to patients’ health and well-being. Most of these tools are based on predefined questionnaires and consensus guidelines. The use of artificial intelligence (AI) allows for automated tools to detect malnutrition in an earlier stage to prevent long-term consequences. In this study, a systematic literature review was carried out with the goal of providing detailed information on what patient groups, screening tools, machine learning algorithms, data types, and variables are being used, as well as the current limitations and implementation stage of these AI-based tools. The results showed that a staggering majority exceeding 90% of all AI models go unused in day-to-day clinical practice. Furthermore, supervised learning models seemed to be the most popular type of learning. Alongside this, disease-related malnutrition was the most common category of malnutrition found in the analysis of all primary studies. This research provides a resource for researchers to identify directions for their research on the use of AI in malnutrition.</p></div>","PeriodicalId":7349,"journal":{"name":"Advances in Nutrition","volume":"15 9","pages":"Article 100264"},"PeriodicalIF":8.0,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S216183132400098X/pdfft?md5=53a7e5b8137242198e4d8f55a968a21c&pid=1-s2.0-S216183132400098X-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141545540","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Effect of Whole-Diet Interventions on Memory and Cognitive Function in Healthy Older Adults – A Systematic Review","authors":"Lina Tingö ,&nbsp;Cecilia Bergh ,&nbsp;Julia Rode ,&nbsp;Maria Fernanda Roca Rubio ,&nbsp;Jonas Persson ,&nbsp;Linnea Brengesjö Johnson ,&nbsp;Lotte H Smit ,&nbsp;Ashley N Hutchinson","doi":"10.1016/j.advnut.2024.100291","DOIUrl":"10.1016/j.advnut.2024.100291","url":null,"abstract":"<div><p>An increasing number of cross-sectional studies suggests that diet may impact memory and cognition in healthy older adults. However, randomized controlled trials investigating the effects of whole-diet interventions on memory and cognition in healthy older adults are rather rare, and conflicting results are often reported. Therefore, a systematic review was conducted to compile the current evidence regarding the potential effects of whole-diet interventions on <em>1</em>) memory and <em>2</em>) other cognitive outcomes in older adults. Studies that reported on randomized controlled trials with dietary interventions in healthy older adults (≥60 y) were included. Studies utilizing supplements, single food items, or trials in specific patient groups (i.e., neurodegenerative diagnoses) were excluded. For the 23 included articles, the main outcomes examined fell into 1 or more of the following categories: cognitive task-based outcomes related to memory, other cognitive task-based outcomes, and additional outcomes related to cognitive function or disease risk. Three of the studies that investigated dietary interventions alone and 2 multidomain studies showed positive effects on memory function, whereas 5 multidomain interventions and 1 intervention that focused on diet alone showed positive effects on other cognitive outcomes. The effect of randomized, controlled whole-diet interventions on memory and cognitive function in healthy older adults is modest and inconclusive, highlighting the need for more well-designed, sufficiently powered studies. Furthermore, the potential mechanisms by which diet impacts cognition in healthy aging need to be elucidated.</p><p>This systematic review is registered in PROSPERO as CRD42022329759.</p></div>","PeriodicalId":7349,"journal":{"name":"Advances in Nutrition","volume":"15 9","pages":"Article 100291"},"PeriodicalIF":8.0,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S216183132400125X/pdfft?md5=667e9f14632fafea01fee319b14620b7&pid=1-s2.0-S216183132400125X-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142001465","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prevalence of and Survival with Cachexia among Patients with Cancer: A Systematic Review and Meta-Analysis","authors":"Tomoya Takaoka ,&nbsp;Akinori Yaegashi ,&nbsp;Daiki Watanabe","doi":"10.1016/j.advnut.2024.100282","DOIUrl":"10.1016/j.advnut.2024.100282","url":null,"abstract":"<div><p>Cachexia is associated with lower overall survival (OS) in patients with cancer; however, the relationship between the two is reported to differ according to the definitive criteria for diagnosing cachexia.</p><p>We aimed to investigate <em>1</em>) the difference in the prevalence of cachexia in patients with cancer and <em>2</em>) the association between cachexia and OS, depending on the definitive criteria for diagnosing cachexia in patients with cancer. We searched PubMed and Web of Science from their inception until July 31, 2023, to identify eligible studies. We conducted a systematic review of the prevalence of cachexia in patients with cancer and performed a meta-analysis to investigate its relationship with OS. A total of 125 articles comprising 137,960 patients were included in the systematic review, and 26 articles consisting of 11,118 patients underwent meta-analysis. The overall prevalence of cachexia in patients with cancer was 33.0% (95% confidence interval [CI]: 32.8, 33.3); however, it varied according to the definitive criteria for diagnosing cachexia (13.9%–56.5%). According to the Fearon 2011 criteria, the prevalence of cachexia was associated with a high hazard ratio (HR) for OS compared with that of noncachexia [HR: 1.58 (95% CI: 1.45, 1.73)]; according to the other criteria, the HR was 2.78 (95% CI: 1.88, 4.11), indicating significant subgroup differences (<em>P</em> = 0.006). The dose–response curve indicated that the HR for OS plateaued at a cachexia prevalence range of 40%–50% (<span>l</span>-shaped relationship). The prevalence of cachexia in patients with cancer may vary depending on the definitive criteria used to diagnose cachexia. The HR for OS was higher for low cachexia prevalence. The definitive criteria should be carefully considered when assessing cachexia in patients with cancer.</p><p>This trial was registered at the PROSPERO as CRD42023435474.</p></div>","PeriodicalId":7349,"journal":{"name":"Advances in Nutrition","volume":"15 9","pages":"Article 100282"},"PeriodicalIF":8.0,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2161831324001169/pdfft?md5=0b2eb374e7a7c75e8af1efcab98e8e1d&pid=1-s2.0-S2161831324001169-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141914762","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evolution of Dietary Diversity: Further Consideration of Contextual and Multidimensional Features","authors":"Kirsten A Herrick ,&nbsp;Jennifer L Lerman","doi":"10.1016/j.advnut.2024.100284","DOIUrl":"10.1016/j.advnut.2024.100284","url":null,"abstract":"","PeriodicalId":7349,"journal":{"name":"Advances in Nutrition","volume":"15 9","pages":"Article 100284"},"PeriodicalIF":8.0,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2161831324001182/pdfft?md5=05b37705c447045d78010d4c56c6acb1&pid=1-s2.0-S2161831324001182-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141984029","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Exploring Multidimensional and Within-Food Group Diversity for Diet Quality and Long-Term Health in High-Income Countries","authors":"Anaëlle Bolo ,&nbsp;Eric Verger ,&nbsp;Hélène Fouillet ,&nbsp;François Mariotti","doi":"10.1016/j.advnut.2024.100278","DOIUrl":"10.1016/j.advnut.2024.100278","url":null,"abstract":"<div><p>Dietary diversity is a crucial component of healthy eating patterns because it ensures nutritional adequacy. Yet, concerns have been raised about the potential risks of its increase, which may reflect excessive consumption of unhealthy foods and higher obesity or cardiometabolic risk, particularly in high-income countries. However, the links between dietary diversity and different health outcomes remain inconclusive because of methodological differences in assessing dietary diversity. Numerous studies, mostly cross-sectional, have assessed dietary diversity using different indicators usually based only on the number of foods or food groups consumed. In this perspective, we emphasize that dietary diversity is a multidimensional concept encompassing the number of foods in the diet (food coverage) but also their relative proportions (food evenness) and the nutritional dissimilarity of foods consumed over time (food complementarity). Consequently, a comprehensive assessment of dietary diversity reflecting all its dimensions, both between and within-food groups, is needed to determine the optimal level of complementarity between and within-food groups required to improve health and diet quality. Moreover, given the prevailing context of abundant highly processed and energy-dense foods in high-income countries, promoting dietary diversity should prioritize nutrient-dense food groups. Until recently, within-food group diversity has received limited attention in research and public health recommendations. Still, it may play a role in improving diet quality and long-term health. This perspective aims to clarify the concept of dietary diversity and suggest research avenues that should be explored to better understand its associations with nutritional adequacy and health among adults in high-income countries.</p></div>","PeriodicalId":7349,"journal":{"name":"Advances in Nutrition","volume":"15 9","pages":"Article 100278"},"PeriodicalIF":8.0,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2161831324001121/pdfft?md5=e0845369e5d5c2628dc52551db16c00c&pid=1-s2.0-S2161831324001121-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142229460","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}