{"title":"Time for Paradigm Shift in Anemia Assessment?","authors":"Melissa F Young","doi":"10.1016/j.advnut.2024.100293","DOIUrl":"10.1016/j.advnut.2024.100293","url":null,"abstract":"","PeriodicalId":7349,"journal":{"name":"Advances in Nutrition","volume":"15 10","pages":"Article 100293"},"PeriodicalIF":8.0,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142433038","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The Current Evidence for Vegetarian and Vegan Diets in the Management of Type 2 Diabetes","authors":"Sabrina Schlesinger , Lukas Schwingshackl","doi":"10.1016/j.advnut.2024.100296","DOIUrl":"10.1016/j.advnut.2024.100296","url":null,"abstract":"","PeriodicalId":7349,"journal":{"name":"Advances in Nutrition","volume":"15 10","pages":"Article 100296"},"PeriodicalIF":8.0,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142433039","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Crystal D Karakochuk , Omar Dary , Monica C Flores-Urrutia , Maria Nieves Garcia-Casal , Chika Hayashi , Maria Elena D Jefferds , Robert Johnston , Leila M Larson , Carine Mapango , Dora I Mazariegos Cordero , Denish Moorthy , Sorrel Namaste , Lisa M Rogers , Kuntal Saha , Sara Wuehler
{"title":"Emerging Evidence and Critical Issues with the Use of Single-Drop Capillary Blood for the Measurement of Hemoglobin Concentration in Population-Level Anemia Surveys","authors":"Crystal D Karakochuk , Omar Dary , Monica C Flores-Urrutia , Maria Nieves Garcia-Casal , Chika Hayashi , Maria Elena D Jefferds , Robert Johnston , Leila M Larson , Carine Mapango , Dora I Mazariegos Cordero , Denish Moorthy , Sorrel Namaste , Lisa M Rogers , Kuntal Saha , Sara Wuehler","doi":"10.1016/j.advnut.2024.100290","DOIUrl":"10.1016/j.advnut.2024.100290","url":null,"abstract":"<div><div>Accurate and precise measurement of hemoglobin concentration is critical for reliable estimations of anemia prevalence at the population level. When systematic and/or random error are introduced in hemoglobin measurement, estimates of anemia prevalence might be significantly erroneous and, hence, limit their usefulness. For decades, single-drop capillary blood has been the most common blood source used for the measurement of hemoglobin concentration in surveys, especially in low-income and middle-income countries. In this study, we highlight historical and emerging evidence that single-drop capillary blood introduces a high degree of random error (variability) to hemoglobin estimates, leading to less reliable estimates of anemia prevalence at the population level. At present, the best practice is to collect and use venous blood for measurement of hemoglobin with an automated hematology analyzer, following standard operating procedures and quality assurance measures. Where use of an automated analyzer is not possible, the analysis of venous blood in a point-of-care hemoglobinometer by trained phlebotomists or specimen collectors should be considered. A forthcoming systematic review will provide additional evidence on the accuracy and precision of single-drop capillary blood for hemoglobin assessment. In the meantime, we raise caution when using single-drop capillary blood for hemoglobin measurement as it can result in inaccurate hemoglobin estimates and less reliable anemia prevalence estimates.</div></div>","PeriodicalId":7349,"journal":{"name":"Advances in Nutrition","volume":"15 10","pages":"Article 100290"},"PeriodicalIF":8.0,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141997001","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Kendra A Tiani , Cristina M Arenaz , Maureen K Spill , Margaret J Foster , Julie S Davis , Regan L Bailey , Martha S Field , Patrick J Stover , Amanda J MacFarlane
{"title":"The Use of Ginger Bioactive Compounds in Pregnancy: An Evidence Scan and Umbrella Review of Existing Meta-Analyses","authors":"Kendra A Tiani , Cristina M Arenaz , Maureen K Spill , Margaret J Foster , Julie S Davis , Regan L Bailey , Martha S Field , Patrick J Stover , Amanda J MacFarlane","doi":"10.1016/j.advnut.2024.100308","DOIUrl":"10.1016/j.advnut.2024.100308","url":null,"abstract":"<div><div>Ginger is a commonly used nonpharmacological treatment of pregnancy-related symptoms including nausea and vomiting, inflammation, and gastrointestinal dysfunction. Determining the efficacy of ginger is particularly important during pregnancy and lactation when maternal and neonatal detrimental effects may be a concern. This evidence scan and umbrella review aimed to assess the extent and quality of the evidence regarding the effectiveness and safety of using dietary preparations of ginger during pregnancy and lactation. We searched MEDLINE, Embase, CAB Abstracts, and International Pharmaceutical Abstracts up to 20 December, 2023, to identify maternal and neonatal outcomes associated with ginger use during pregnancy or lactation compared to placebo or conventional medicines. Outcomes for which a meta-analysis (MA) of intervention studies was identified were synthesized in an umbrella review. The AMSTAR-2 (A MeaSurement Tool to Assess systematic Reviews-2) tool was used to critically appraise the reviews. The percent overlap in primary studies was calculated overall and pairwise for each included MA. Data extracted from each MA included the summary estimate of the effect of ginger, the formulation of the ginger treatment, gestational timepoint at intervention, population enrolled in the study, type of intervention, comparator intervention, and number of study participants. The evidence scan identified 90 articles relevant to ginger use during pregnancy and lactation. Seven MAs of ginger use for treating nausea and vomiting of pregnancy reported 22 independent studies with a 49% study overlap overall. The majority of the MAs found a significant positive effect of ginger on the improvement of nausea in pregnancy compared with placebo, or equivalence to conventional treatments, and no evidence of significant adverse effects. The quality of the MAs ranged from critically low to low. The evidence suggests that ginger is effective at reducing nausea in pregnancy; however, the included studies contained substantial heterogeneity and were of low quality.</div></div>","PeriodicalId":7349,"journal":{"name":"Advances in Nutrition","volume":"15 11","pages":"Article 100308"},"PeriodicalIF":8.0,"publicationDate":"2024-09-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142333480","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The Role of Iron in Intestinal Mucus: Perspectives from Both the Host and Gut Microbiota","authors":"Shuan Liu , Jie Yin , Dan Wan , Yulong Yin","doi":"10.1016/j.advnut.2024.100307","DOIUrl":"10.1016/j.advnut.2024.100307","url":null,"abstract":"<div><div>Although research on the role of iron in host immunity has a history spanning decades, it is only relatively recently that attention has been directed toward the biological effects of iron on the intestinal mucus layer, prompted by an evolving understanding of the role of this material in immune defense. The mucus layer, secreted by intestinal goblet cells, covers the intestinal epithelium, and given its unique location, interactions between the host and gut microbiota, as well as among constituent microbiota, occur frequently within the mucus layer. Iron, as an essential nutrient for the vast majority of life forms, regulates immune responses from both the host and microbial perspectives. In this review, we summarize the iron metabolism of both the host and gut microbiota and describe how iron contributes to intestinal mucosal homeostasis via the intestinal mucus layer with respect to both host and constituent gut microbiota. The findings described herein offer a new perspective on iron-mediated intestinal mucosal barrier function.</div></div>","PeriodicalId":7349,"journal":{"name":"Advances in Nutrition","volume":"15 11","pages":"Article 100307"},"PeriodicalIF":8.0,"publicationDate":"2024-09-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142333479","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Faith E Bala , Katlyn E McGrattan , Christina J Valentine , Sudarshan R Jadcherla
{"title":"A Narrative Review of Strategies to Optimize Nutrition, Feeding, and Growth among Preterm-Born Infants: Implications for Practice","authors":"Faith E Bala , Katlyn E McGrattan , Christina J Valentine , Sudarshan R Jadcherla","doi":"10.1016/j.advnut.2024.100305","DOIUrl":"10.1016/j.advnut.2024.100305","url":null,"abstract":"<div><div>Preterm birth is the leading cause of neonatal and under-5 mortality globally, and healthcare-related burden and nutrition-related morbidities are unsustainable, particularly in resource-limited regions. Additionally, preterm infants are susceptible to multiple adverse outcomes including growth faltering, suboptimal neurodevelopment, and multisystemic morbidities. Maturation, healing, repair, and restoration to normalcy in preterm-born infants require optimizing nutrition; only then, prognosis, growth, neurodevelopment, and overall quality of life can improve. In this article, we discuss the various evidence-based feeding and nutritional strategies that can be applicable even in resource-limited settings, where resources and infrastructure for advanced neonatal care are limited. This article addresses nutrition, feeding strategies, and growth monitoring in the neonatal intensive care unit and at discharge to optimize nutrition, growth, and development.</div></div>","PeriodicalId":7349,"journal":{"name":"Advances in Nutrition","volume":"15 11","pages":"Article 100305"},"PeriodicalIF":8.0,"publicationDate":"2024-09-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142309225","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Andrea Santos-Guzmán , Juan A Rivera , Mishel Unar-Munguía , Ivonne Ramírez-Silva
{"title":"Addressing Infant and Young Child Feeding Recommendations From a Planetary Health Perspective","authors":"Andrea Santos-Guzmán , Juan A Rivera , Mishel Unar-Munguía , Ivonne Ramírez-Silva","doi":"10.1016/j.advnut.2024.100303","DOIUrl":"10.1016/j.advnut.2024.100303","url":null,"abstract":"<div><div>Current international infant and young child (IYC) feeding recommendations consider nutrition and health but not environmental impacts. Only a handful of countries have dietary guidelines that provide quantitative recommendations for food groups of environmental concern. This study aimed to perform a narrative review of the environmental impacts of commercial milk formula compared with breastfeeding and to analyze the degree to which current country-specific IYC feeding recommendations are aligned with sustainable dietary targets. A mixed-methods review was conducted, including the following: <em>1</em>) a narrative review of the environmental impact of commercial milk formula compared with breastfeeding and <em>2</em>) a comparison of recommended intake of meats and dairy for children IYC based on country-specific dietary guidelines compared with the EAT–Lancet Commission dietary targets (ELCT) for children 24 mo or older and adults and if the ELCT should be adjusted for the energy needs of IYC. Formula feeding has a greater environmental impact (∼48% higher carbon footprint) than exclusive breastfeeding. Available country-specific dietary guidelines for meat and dairy products in children IYC are, in general, at or below the upper limits of the ELCT recommended ranges for older children and adults but are in most cases above the upper limit when adjusting for the energy needs of IYC. Exclusive breastfeeding should be protected and promoted not only as the healthier but also as the most sustainable alternative. Available complementary dietary feeding recommendations of nonprocessed meat and dairy fall below current ELCT for older children and adults. Given that IYC require a more nutrient-dense diet than older children and adults and considering the small quantities they consume, we recommend using the unadjusted ELCT as reference for IYC feeding while specific international consumption recommendations are developed for this age group.</div></div>","PeriodicalId":7349,"journal":{"name":"Advances in Nutrition","volume":"15 11","pages":"Article 100303"},"PeriodicalIF":8.0,"publicationDate":"2024-09-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142302208","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Gina L Tripicchio , Alissa D Smethers , Jessica J Johnson , Jordan A Olenginski , Diane M O’Brien , Jennifer Orlet Fisher , Vitalina A Robinson , Sarah H Nash
{"title":"The Carbon Isotope Ratio as an Objective Biomarker of Added Sugar Intake: A Scoping Review of Current Evidence in Human Nutrition","authors":"Gina L Tripicchio , Alissa D Smethers , Jessica J Johnson , Jordan A Olenginski , Diane M O’Brien , Jennifer Orlet Fisher , Vitalina A Robinson , Sarah H Nash","doi":"10.1016/j.advnut.2024.100281","DOIUrl":"10.1016/j.advnut.2024.100281","url":null,"abstract":"<div><p>Objective biomarkers of dietary intake are needed to advance nutrition research. The carbon isotope ratio (C<sup>13</sup>/C<sup>12</sup>; CIR) holds promise as an objective biomarker of added sugar (AS) and sugar-sweetened beverage (SSB) intake. This systematic scoping review presents the current evidence on CIRs from human studies. Search results (through April 12, 2024) yielded 6297 studies and 24 final articles. Studies were observational (<em>n</em> = 12), controlled feeding (<em>n</em> = 10), or dietary interventions (<em>n</em> = 2). CIRs were sampled from blood (<em>n</em> = 23), hair (<em>n</em> = 5), breath (<em>n</em> = 2), and/or adipose tissue (<em>n</em> = 1). Most (<em>n</em> = 17) conducted whole tissue (that is, bulk) analysis, 8 used compound specific isotope analysis (CSIA), and/or 2 studies used methods appropriate for analyzing breath. Studies were conducted in 3 concentrated geographic regions of the United States (<em>n</em> = 7 Virginia; <em>n</em> = 5 Arizona; <em>n</em> = 4 Alaska), with only 2 studies conducted in other countries. Studies that used CSIA to examine the CIR from the amino acid alanine (CIR-Ala; <em>n</em> = 4) and CIR analyzed from breath (<em>n</em> = 2) provided the most robust evidence for CIR as an objective biomarker of AS and SSBs (<em>R</em><sup>2</sup> range 0.36–0.91). Studies using bulk analysis of hair or blood showed positive, but modest and more variable associations with AS and SSBs (<em>R</em><sup>2</sup> range 0.05–0.48). Few studies showed no association, particularly in non-United States populations and those with low AS and SSB intakes. Two studies provided evidence for CIR to detect changes in SSB intake in response to dietary interventions. Overall, the most compelling evidence supports CIR-Ala as an objective indicator of AS intake and breath CIR as an indicator of short-term AS intake. Considering how to adjust for underlying dietary patterns remains an important area of future work and emerging methods using breath and CSIA warrant additional investigation. More evidence is needed to refine the utility and specificity of CIRs to measure AS and SSB intake.</p></div>","PeriodicalId":7349,"journal":{"name":"Advances in Nutrition","volume":"15 9","pages":"Article 100281"},"PeriodicalIF":8.0,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2161831324001157/pdfft?md5=3ee75ff60a5fc2c1436520b795265149&pid=1-s2.0-S2161831324001157-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141879934","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Artificial Intelligence in Malnutrition: A Systematic Literature Review","authors":"","doi":"10.1016/j.advnut.2024.100264","DOIUrl":"10.1016/j.advnut.2024.100264","url":null,"abstract":"<div><p>Malnutrition among the population of the world is a frequent yet underdiagnosed problem in both children and adults. Development of malnutrition screening and diagnostic tools for early detection of malnutrition is necessary to prevent long-term complications to patients’ health and well-being. Most of these tools are based on predefined questionnaires and consensus guidelines. The use of artificial intelligence (AI) allows for automated tools to detect malnutrition in an earlier stage to prevent long-term consequences. In this study, a systematic literature review was carried out with the goal of providing detailed information on what patient groups, screening tools, machine learning algorithms, data types, and variables are being used, as well as the current limitations and implementation stage of these AI-based tools. The results showed that a staggering majority exceeding 90% of all AI models go unused in day-to-day clinical practice. Furthermore, supervised learning models seemed to be the most popular type of learning. Alongside this, disease-related malnutrition was the most common category of malnutrition found in the analysis of all primary studies. This research provides a resource for researchers to identify directions for their research on the use of AI in malnutrition.</p></div>","PeriodicalId":7349,"journal":{"name":"Advances in Nutrition","volume":"15 9","pages":"Article 100264"},"PeriodicalIF":8.0,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S216183132400098X/pdfft?md5=53a7e5b8137242198e4d8f55a968a21c&pid=1-s2.0-S216183132400098X-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141545540","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}