Advances in Nutrition最新文献

{"title":"Conceptualization and Assessment of 24-H Timing of Eating and Energy Intake: A Methodological Systematic Review of the Chronic Disease Literature","authors":"Sydney G O'Connor ,&nbsp;Lauren E O’Connor ,&nbsp;Kelly A Higgins ,&nbsp;Brooke M Bell ,&nbsp;Emily S Krueger ,&nbsp;Rita Rawal ,&nbsp;Reiley Hartmuller ,&nbsp;Jill Reedy ,&nbsp;Marissa M Shams-White","doi":"10.1016/j.advnut.2024.100178","DOIUrl":"10.1016/j.advnut.2024.100178","url":null,"abstract":"<div><p>Timing of eating (TOE) and energy intake (TOEI) has important implications for chronic disease risk beyond diet quality. The 2020 Dietary Guidelines Advisory Committee recommended developing consistent terminology to address the lack of TOE/TOEI standardization. The primary objective of this methodological systematic review was to characterize the conceptualization and assessment of TOE/TOEI within the chronic disease literature (International Prospective Register of Systematic Reviews registration number: CRD42021236621). Literature searches in Cumulative Index to Nursing and Allied Health Literature (CINAHL) Plus, Embase, PubMed, and Scopus were limited to English language publications from 2000 to August 2022. Eligible studies reported the association between TOE/TOEI and obesity, cardiovascular disease, type 2 diabetes mellitus, cancer, or a related clinical risk factor among adults (≥19 y) in observational and intervention studies. A qualitative synthesis described and compared TOE/TOEI conceptualization, definitions, and assessment methods across studies. Of the 7579 unique publications identified, 259 studies (observational [51.4 %], intervention [47.5 %], or both [1.2 %]) were eligible for inclusion. Key findings indicated that most studies (49.6 %) were conducted in the context of obesity and body weight. TOE/TOEI variables or assigned conditions conceptualized interrelated aspects of time and eating or energy intake in varying ways. Common TOE/TOEI conceptualizations included the following: <em>1</em>) timepoint (specific time to represent when intake occurs, such as time of breakfast [74.8 %]); <em>2</em>) duration (length of time or interval when intake does/does not occur, such as “eating window” [56.5 %]); <em>3</em>) distribution (proportion of daily intake at a given time interval, such as “percentage of energy before noon” [29.8 %]); and <em>4</em>) cluster (grouping individuals based on temporal ingestive characteristics [5.0 %]). Assessment, definition, and operationalization of 24-h TOE/TOEI variables varied widely across studies. Observational studies most often used surveys or questionnaires (28.9 %), whereas interventions used virtual or in-person meetings (23.8 %) to assess TOE/TOEI adherence. Overall, the diversity of terminology and methods solidifies the need for standardization to guide future research in chrononutrition and to facilitate inter-study comparisons.</p></div>","PeriodicalId":7349,"journal":{"name":"Advances in Nutrition","volume":null,"pages":null},"PeriodicalIF":9.3,"publicationDate":"2024-01-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2161831324000127/pdfft?md5=7f7270fa9cf575440f2423d42aa6c935&pid=1-s2.0-S2161831324000127-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139503270","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Association between Dietary Inflammatory Potential and Urologic Cancers: True Association or Bias?","authors":"Yiwen Zhang,&nbsp;Edward Giovannucci","doi":"10.1016/j.advnut.2023.10.005","DOIUrl":"10.1016/j.advnut.2023.10.005","url":null,"abstract":"","PeriodicalId":7349,"journal":{"name":"Advances in Nutrition","volume":null,"pages":null},"PeriodicalIF":9.3,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2161831323013923/pdfft?md5=728090430d90852864b39b8adfbd78d8&pid=1-s2.0-S2161831323013923-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135410763","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Role of Diet in the Prevention of Hypertension and Management of Blood Pressure: An Umbrella Review of Meta-Analyses of Interventional and Observational Studies","authors":"Ghadeer S. Aljuraiban ,&nbsp;Rachel Gibson ,&nbsp;Doris SM. Chan ,&nbsp;Linda Van Horn ,&nbsp;Queenie Chan","doi":"10.1016/j.advnut.2023.09.011","DOIUrl":"10.1016/j.advnut.2023.09.011","url":null,"abstract":"<div><p>High blood pressure (BP) is a major pathological risk factor for the development of several cardiovascular diseases. Diet is a key modifier of BP, but the underlying relationships are not clearly demonstrated. This is an umbrella review of published meta-analyses to critically evaluate the wide range of dietary evidence from bioactive compounds to dietary patterns on BP and risk of hypertension. PubMed, Embase, Web of Science, and Cochrane Central Register of Controlled Trials were searched from inception until October 31, 2021, for relevant meta-analyses of randomized controlled trials or meta-analyses of observational studies. A total of 175 publications reporting 341 meta-analyses of randomized controlled trials (145 publications) and 70 meta-analyses of observational studies (30 publications) were included in the review. The methodological quality of the included publications was assessed using Assessment of Multiple Systematic Reviews 2 and the evidence quality of each selected meta-analysis was assessed using NutriGrade. This umbrella review supports recommended public health guidelines for prevention and control of hypertension. Dietary patterns including the Dietary Approaches to Stop Hypertension and the Mediterranean-type diets that further restrict sodium, and moderate alcohol intake are advised. To produce high-quality evidence and substantiate strong recommendations, future research should address areas where the low quality of evidence was observed (for example, intake of dietary fiber, fish, egg, meat, dairy products, fruit juice, and nuts) and emphasize focus on dietary factors not yet conclusively investigated.</p></div>","PeriodicalId":7349,"journal":{"name":"Advances in Nutrition","volume":null,"pages":null},"PeriodicalIF":9.3,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2161831323013844/pdfft?md5=ed22a53e21d30cbe414cc9b8844cb940&pid=1-s2.0-S2161831323013844-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41158731","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Effects of Bifidobacterium Probiotic Supplementation on Blood Glucose: A Systematic Review and Meta-Analysis of Animal Models and Clinical Evidence","authors":"Emily P. Van Syoc ,&nbsp;Janhavi Damani ,&nbsp;Zachary DiMattia ,&nbsp;Erika Ganda ,&nbsp;Connie J. Rogers","doi":"10.1016/j.advnut.2023.10.009","DOIUrl":"10.1016/j.advnut.2023.10.009","url":null,"abstract":"<div><p>Probiotic supplementation is a potential therapeutic for metabolic diseases, including obesity, metabolic syndrome (MetS), and type 2 diabetes (T2D), but most studies deliver multiple species of bacteria in addition to prebiotics or oral pharmaceuticals. This may contribute to conflicting evidence in existing meta-analyses of probiotics in these populations and warrants a systematic review of the literature to assess the contribution of a single probiotic genus to better understand the contribution of individual probiotics to modulate blood glucose. We conducted a systematic review and meta-analysis of animal studies and human randomized controlled trials (RCTs) to assess the effects of <em>Bifidobacterium</em> (<em>BF</em>) probiotic supplementation on markers of glycemia. In a meta-analysis of 6 RCTs, <em>BF</em> supplementation had no effect on fasting blood glucose {FBG; mean difference [MD] = −1.99 mg/dL [95% confidence interval (CI): −4.84, 0.86], <em>P</em> = 0.13}, and there were no subgroup differences between subjects with elevated FBG concentrations and normoglycemia. However, <em>BF</em> supplementation reduced FBG concentrations in a meta-analysis comprised of studies utilizing animal models of obesity, MetS, or T2D [<em>n =</em> 16; MD = −36.11 mg/dL (CI: −49.04, −23.18), <em>P</em> &lt; 0.0001]. Translational gaps from animal to human trials include paucity of research in female animals, <em>BF</em> supplementation in subjects that were normoglycemic, and lack of methodologic reporting regarding probiotic viability and stability. More research is necessary to assess the effects of <em>BF</em> supplementation in human subjects with elevated FBG concentrations. Overall, there was consistent evidence of the efficacy of <em>BF</em> probiotics to reduce elevated FBG concentrations in animal models but not clinical trials, suggesting that <em>BF</em> alone may have minimal effects on glycemic control, may be more effective when combined with multiple probiotic species, or may be more effective in conditions of hyperglycemia rather than elevated FBG concentrations.</p></div>","PeriodicalId":7349,"journal":{"name":"Advances in Nutrition","volume":null,"pages":null},"PeriodicalIF":9.3,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2161831323013984/pdfft?md5=864e5955206d5fa6da355e38ca2d7f27&pid=1-s2.0-S2161831323013984-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71489517","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Methods for Assessing Health Outcomes Associated with Food Insecurity in the United States College Student Population: A Narrative Review","authors":"Marcela D. Radtke ,&nbsp;Francene M. Steinberg ,&nbsp;Rachel E. Scherr","doi":"10.1016/j.advnut.2023.10.004","DOIUrl":"10.1016/j.advnut.2023.10.004","url":null,"abstract":"<div><p>In the United States, college students experience disproportionate food insecurity (FI) rates compared to the national prevalence. The experience of acute and chronic FI has been associated with negative physical and mental health outcomes in this population. This narrative review aims to summarize the current methodologies for assessing health outcomes associated with the experience of FI in college students in the United States. To date, assessing the health outcomes of FI has predominately consisted of subjective assessments, such as self-reported measures of dietary intake, perceived health status, stress, depression, anxiety, and sleep behaviors. This review, along with the emergence of FI as an international public health concern, establishes the need for novel, innovative, and objective biomarkers to evaluate the short- and long-term impacts of FI on physical and mental health outcomes in college students. The inclusion of objective biomarkers will further elucidate the relationship between FI and a multitude of health outcomes to better inform strategies for reducing the pervasiveness of FI in the United States college student population.</p></div>","PeriodicalId":7349,"journal":{"name":"Advances in Nutrition","volume":null,"pages":null},"PeriodicalIF":9.3,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2161831323013935/pdfft?md5=973293d3d75e40c595d8d78bd1c97e1f&pid=1-s2.0-S2161831323013935-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49685553","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Causes of Low Milk Supply: The Roles of Estrogens, Progesterone, and Related External Factors","authors":"Xuehua Jin ,&nbsp;Sharon L. Perrella ,&nbsp;Ching Tat Lai ,&nbsp;Nicolas L. Taylor ,&nbsp;Donna T. Geddes","doi":"10.1016/j.advnut.2023.10.002","DOIUrl":"10.1016/j.advnut.2023.10.002","url":null,"abstract":"<div><p>Low milk supply (LMS) poses a significant challenge to exclusive and continued breastfeeding, affecting ∼10% to 15% of mothers. Milk production is intricately regulated by both endocrine and autocrine control mechanisms, with estrogens and progesterone playing pivotal roles in this process. In addition to endogenously produced hormones, external substances capable of interfering with normal hormonal actions, including phytoestrogens, mycoestrogens, synthetic estrogens, and hormonal contraceptives, can influence milk production. The effects of these extrinsic hormones on milk production may vary based on maternal body mass index. This comprehensive review examines the multifaceted causes of LMS, focusing on the involvement of estrogens, progesterone, and related external factors in milk production. Furthermore, it investigates the interplay between hormonal factors and obesity, aiming to elucidate the endocrine mechanisms underlying obesity-associated LMS. Insights from this review provide valuable perspectives for developing interventions to improve milk production and address the challenges associated with LMS.</p></div>","PeriodicalId":7349,"journal":{"name":"Advances in Nutrition","volume":null,"pages":null},"PeriodicalIF":9.3,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S216183132301390X/pdfft?md5=c6fb7f23162d36a2d8cb345ae6daad61&pid=1-s2.0-S216183132301390X-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41221544","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparison of the Effect of Daily Vitamin D2 and Vitamin D3 Supplementation on Serum 25-Hydroxyvitamin D Concentration (Total 25(OH)D, 25(OH)D2, and 25(OH)D3) and Importance of Body Mass Index: A Systematic Review and Meta-Analysis","authors":"Ellen GHM. van den Heuvel ,&nbsp;Paul Lips ,&nbsp;Linda J. Schoonmade ,&nbsp;Susan A. Lanham-New ,&nbsp;Natasja M. van Schoor","doi":"10.1016/j.advnut.2023.09.016","DOIUrl":"10.1016/j.advnut.2023.09.016","url":null,"abstract":"<div><h3>Background</h3><p>Two previous meta-analyses showed smaller differences between vitamin D3 and vitamin D2 in raising serum 25-hydroxyvitamin D [25(OH)D] and a consistently high heterogeneity when only including daily dosing studies.</p></div><div><h3>Objective</h3><p>This study aimed to compare more frequently dosed vitamin D2 and vitamin D3 in improving total 25(OH)D and determine the concomitant effect of response modifiers on heterogeneity, and secondly, to compare the vitamin D2-associated change in 25(OH)D2 with the vitamin D3-associated change in 25(OH)D3.</p></div><div><h3>Methods</h3><p>PubMed, EMBASE, Cochrane, and the Web of Science Core collection were searched for randomized controlled trials of vitamin D2 compared with vitamin D3, daily or once/twice weekly dosed. After screening for eligibility, relevant data were extracted for meta-analyses to determine the standardized mean difference when different methods of 25(OH)D analyses were used. Otherwise, the weighted mean difference (WMD) was determined.</p></div><div><h3>Results</h3><p>Overall, the results based on 20 comparative studies showed vitamin D3 to be superior to vitamin D2 in raising total 25(OH)D concentrations, but vitamin D2 and vitamin D3 had a similar positive impact on their corresponding 25(OH)D hydroxylated forms. The WMD in change in total 25(OH)D based on 12 daily dosed vitamin D2-vitamin D3 comparisons, analyzed using liquid chromatography-tandem mass spectrometry, was 10.39 nmol/L (40%) lower for the vitamin D2 group compared with the vitamin D3 group (95% confidence interval: −14.62, −6.16; <em>I</em>^<em>2</em> = 64%; <em>P</em> &lt; 00001). Body mass index (BMI) appeared to be the strongest response modifier, reducing heterogeneity to 0% in both subgroups. The vitamin D2- and vitamin D3-induced change in total 25(OH)D lost significance predominantly in subjects with a BMI &gt;25 kg/m² (<em>P</em> = 0.99). However, information on BMI was only available in 13/17 daily dosed comparisons.</p></div><div><h3>Conclusions</h3><p>Vitamin D3 leads to a greater increase of 25(OH)D than vitamin D2, even if limited to daily dose studies, but vitamin D2 and vitamin D3 had similar positive impacts on their corresponding 25(OH)D hydroxylated forms. Next to baseline 25(OH)D concentration, BMI should be considered when comparing the effect of daily vitamin D2 and vitamin D3 supplementation on total 25(OH)D concentration.</p><p>This study was registered in PROSPERO as CRD42021272674.</p></div>","PeriodicalId":7349,"journal":{"name":"Advances in Nutrition","volume":null,"pages":null},"PeriodicalIF":9.3,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2161831323013947/pdfft?md5=cab5c0e9d2dfcacd6302965b4f8942c4&pid=1-s2.0-S2161831323013947-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49685552","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Human Milk Macronutrients and Child Growth and Body Composition in the First Two Years: A Systematic Review","authors":"Meredith (Merilee) Brockway ,&nbsp;Allison I. Daniel ,&nbsp;Sarah M. Reyes ,&nbsp;Matthew Granger ,&nbsp;Joann M. McDermid ,&nbsp;Deborah Chan ,&nbsp;Rebecca Refvik ,&nbsp;Karanbir K. Sidhu ,&nbsp;Suad Musse ,&nbsp;Pooja P. Patel ,&nbsp;Caroline Monnin ,&nbsp;Larisa Lotoski ,&nbsp;Donna Geddes ,&nbsp;Fyezah Jehan ,&nbsp;Patrick Kolsteren ,&nbsp;Lindsay H. Allen ,&nbsp;Daniela Hampel ,&nbsp;Kamilla G. Eriksen ,&nbsp;Natalie Rodriguez ,&nbsp;Meghan B. Azad","doi":"10.1016/j.advnut.2023.100149","DOIUrl":"10.1016/j.advnut.2023.100149","url":null,"abstract":"<div><p>Among exclusively breastfed infants, human milk (HM) provides complete nutrition in the first mo of life and remains an important energy source as long as breastfeeding continues. Consisting of digestible carbohydrates, proteins, and amino acids, as well as fats and fatty acids, macronutrients in human milk have been well studied; however, many aspects related to their relationship to growth in early life are still not well understood. We systematically searched Medline, EMBASE, the Cochrane Library, Scopus, and Web of Science to synthesize evidence published between 1980 and 2022 on HM components and anthropometry through 2 y of age among term-born healthy infants. From 9992 abstracts screened, 57 articles reporting observations from 5979 dyads were included and categorized based on their reporting of HM macronutrients and infant growth.</p><p>There was substantial heterogeneity in anthropometric outcome measurement, milk collection timelines, and HM sampling strategies; thus, meta-analysis was not possible. In general, digestible carbohydrates were positively associated with infant weight outcomes. Protein was positively associated with infant length, but no associations were reported for infant weight. Finally, HM fat was not consistently associated with any infant growth metrics, though various associations were reported in single studies. Fatty acid intakes were generally positively associated with head circumference, except for docosahexaenoic acid. Our synthesis of the literature was limited by differences in milk collection strategies, heterogeneity in anthropometric outcomes and analytical methodologies, and by insufficient reporting of results. Moving forward, HM researchers should accurately record and account for breastfeeding exclusivity, use consistent sampling protocols that account for the temporal variation in HM macronutrients, and use reliable, sensitive, and accurate techniques for HM macronutrient analysis.</p></div>","PeriodicalId":7349,"journal":{"name":"Advances in Nutrition","volume":null,"pages":null},"PeriodicalIF":9.3,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2161831323014333/pdfft?md5=584f1c4dff388e6b6e1d6db2f6269733&pid=1-s2.0-S2161831323014333-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138048957","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Human Milk Micronutrients and Child Growth and Body Composition in the First 2 years: A Systematic Review","authors":"Sarah M. Reyes ,&nbsp;Meredith (Merilee) Brockway ,&nbsp;Joann M. McDermid ,&nbsp;Deborah Chan ,&nbsp;Matthew Granger ,&nbsp;Rebecca Refvik ,&nbsp;Karanbir K. Sidhu ,&nbsp;Suad Musse ,&nbsp;Caroline Monnin ,&nbsp;Larisa Lotoski ,&nbsp;Donna T. Geddes ,&nbsp;Fyezah Jehan ,&nbsp;Patrick Kolsteren ,&nbsp;Lindsay H. Allen ,&nbsp;Daniela Hampel ,&nbsp;Kamilla G. Eriksen ,&nbsp;Natalie Rodriguez ,&nbsp;Meghan B. Azad","doi":"10.1016/j.advnut.2023.06.005","DOIUrl":"10.1016/j.advnut.2023.06.005","url":null,"abstract":"<div><p>Human milk (HM) provides a plethora of nutritional and non-nutritional compounds that support infant development. For many compounds, concentrations vary substantially among mothers and across lactation, and their impact on infant growth is poorly understood. We systematically searched MEDLINE, Embase, the Cochrane Library, Scopus, and Web of Science to synthesize evidence published between 1980 and 2022 on HM components and anthropometry through 2 y of age among term-born infants. Outcomes included weight-for-length, length-for-age, weight-for-age, body mass index (in kg/m²)–for–age, and growth velocity. From 9992 abstracts screened, 144 articles were included and categorized based on their reporting of HM micronutrients, macronutrients, or bioactive components. Micronutrients (vitamins and minerals) are reported here, based on 28 articles involving 2526 mother-infant dyads. Studies varied markedly in their designs, sampling times, geographic and socioeconomic settings, reporting practices, and the HM analytes and infant anthropometrics measured. Meta-analysis was not possible because data were sparse for most micronutrients. The most-studied minerals were zinc (15 articles, 1423 dyads) and calcium (7 articles, 714 dyads). HM iodine, manganese, calcium, and zinc concentrations were positively associated with several outcomes (each in ≥2 studies), whereas magnesium (in a single study) was negatively associated with linear growth during early lactation. However, few studies measured HM intake, adjusted for confounders, provided adequate information about complementary and formula feeding, or adequately described HM collection protocols. Only 4 studies (17%) had high overall quality scores. The biological functions of individual HM micronutrients are likely influenced by other HM components; yet, only 1 study analyzed data from multiple micronutrients simultaneously, and few addressed other HM components. Thus, available evidence on this topic is largely inconclusive and fails to address the complex composition of HM. High-quality research employing chronobiology and systems biology approaches is required to understand how HM components work independently and together to influence infant growth and to identify new avenues for future maternal, newborn, or infant nutritional interventions.</p></div>","PeriodicalId":7349,"journal":{"name":"Advances in Nutrition","volume":null,"pages":null},"PeriodicalIF":9.3,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2161831323013261/pdfft?md5=cb901f03bc73068317f404f31b05beb7&pid=1-s2.0-S2161831323013261-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9931082","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effects of Early Diet on the Prevalence of Allergic Disease in Children: A Systematic Review and Meta-Analysis","authors":"Shumin Wang ,&nbsp;Pingping Yin ,&nbsp;Leilei Yu ,&nbsp;Fengwei Tian ,&nbsp;Wei Chen ,&nbsp;Qixiao Zhai","doi":"10.1016/j.advnut.2023.10.001","DOIUrl":"10.1016/j.advnut.2023.10.001","url":null,"abstract":"<div><p>Recent evidence suggests that the timing of introduction, types, and amounts of complementary foods/allergenic foods may influence the risk of allergic disease. However, the evidence has not been updated and comprehensively synthesized. The Cochrane Library, EMBASE, Web of Science, and PubMed databases were searched from the inception of each database up to 31 May 2023 (articles prior to 2000 were excluded manually). Statistical analyses were performed using RevMan 5. The GRADE approach was followed to rate the certainty of evidence. Compared with &gt;6 mo, early introduction of eggs (≤6 mo of age) might reduce the risk of food allergies in preschoolers aged &lt;6 y (odds ratio [OR], 0.65; 95% confidence interval [CI], 0.53, 0.81), but had no effect on asthma or atopic dermatitis (AD). Consumption of fish at 6–12 mo might reduce the risk of asthma in children (aged 5–17 y) compared with late introduction after 12 mo (OR, 0.61; 95% CI: 0.52, 0.72). Introduction of allergenic foods for ≤6 mo of age, compared with &gt;6 mos, was a protective factor for the future risk (children aged ≤10 y) of AD (OR, 0.93; 95% CI: 0.89, 0.97). Probiotic intervention for infants at high risk of allergic disease significantly reduced the risk of food allergy at ages 0–3 y (OR, 0.72; 95% CI: 0.56, 0.94), asthma at 6–12 y (OR, 0.61; 95% CI: 0.41, 0.90), and AD at aged &lt;6 y (3–6 y: OR, 0.70; 95% CI: 0.52, 0.94; 0–3 y: OR, 0.73; 95% CI: 0.59, 0.91). Early introduction of complementary foods or the high-dose vitamin D supplementation in infancy was not associated with the risk of developing food allergies, asthma, or AD during childhood. Early introduction to potential allergen foods for normal infants or probiotics for infants at high risk of allergies may protect against development of allergic disease. This study was registered at PROSPERO as CRD42022379264.</p></div>","PeriodicalId":7349,"journal":{"name":"Advances in Nutrition","volume":null,"pages":null},"PeriodicalIF":9.3,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2161831323013893/pdfft?md5=67a2c281192a698f65338df6638075f3&pid=1-s2.0-S2161831323013893-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41221545","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}