Advances in integrative medicine最新文献

{"title":"Corrigendum to “Artificial intelligence versus human analysis: Interpreting data in elderly fat reduction study” [Adv. Integr. Med. 12 (1) (2025) 13–18]","authors":"Mariusz Konieczny, Piotr Sporek","doi":"10.1016/j.aimed.2025.100488","DOIUrl":"10.1016/j.aimed.2025.100488","url":null,"abstract":"","PeriodicalId":7343,"journal":{"name":"Advances in integrative medicine","volume":"12 2","pages":"Article 100488"},"PeriodicalIF":1.7,"publicationDate":"2025-04-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144147285","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Development, validation, and feasibility of integrated Yoga module for Internet Gaming Disorder among adolescents","authors":"Nagalakshmi S. Rao ,&nbsp;Raghavendra Bhat ,&nbsp;Manoj Kumar Sharma ,&nbsp;Alaka Mani T L","doi":"10.1016/j.aimed.2025.100486","DOIUrl":"10.1016/j.aimed.2025.100486","url":null,"abstract":"<div><h3>Background</h3><div>Internet gaming is a popular leisure activity among adolescents, but excessive use can lead to Internet Gaming Disorder (IGD). IGD has been associated with negative health outcomes, including increased stress, obesity, decreased academic performance, and mental health issues. To address this, we developed a Yoga module leveraging Yoga’s known health benefits as a potential intervention for IGD.</div></div><div><h3>Methods</h3><div>The study was conducted in three stages. In the first stage, the Yoga module was developed by a scientific and traditional literature review on Yoga, followed by group discussion with five Yoga experts and one psychiatrist. In the second stage, the developed module was sent to 45 Yoga experts, out of which 25 experts provided feedback. The Lawshe’s Content Validity Ratio(CVR)method was used for the content validity of the Yoga module. Stage three, feasibility study was conducted using randomized controlled trial. Thirty subjects were randomly allocated to Yoga (n = 15) and control group (n = 15). They were assessed after one month of intervention.</div></div><div><h3>Results</h3><div>Thirty Yoga practices (30 out of 34) with Lawshe’s Content Validity ratio ≥ 0.37 were retained (88 %) in the final Yoga Module.The pilot study demonstrated a significant difference by Independent sample t-test comparing the Yoga group and Control group in the variable WHO Quality of Life (QOL) – Social (P &lt; 0.05) d = 0.951, Loneliness (P &lt; 0.001), d = 2.396, Mind Wandering (P &lt; 0.05), d = 0.839 and Parental Internet Gaming Disorder(P &lt; 0.001), d = 3.014.</div></div><div><h3>Conclusion</h3><div>The present study offers a validated Yoga module for adolescents with IGD. The pilot study suggests that the module is feasible and easy to practice. To gain maximum benefits, we recommend that this module be practiced at least three times a week (40 min each session) under the supervision of a Yoga expert.</div></div>","PeriodicalId":7343,"journal":{"name":"Advances in integrative medicine","volume":"12 3","pages":"Article 100486"},"PeriodicalIF":1.7,"publicationDate":"2025-04-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144471970","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Medicinal plants use by patients at a Moroccan University Hospital: A cross-sectional study","authors":"El Mahdi Razzok ,&nbsp;Hassane Mekhfi ,&nbsp;Naima Abda ,&nbsp;Asmae Lekfif ,&nbsp;Najib Dahbi ,&nbsp;Yassamine Bentata","doi":"10.1016/j.aimed.2025.100487","DOIUrl":"10.1016/j.aimed.2025.100487","url":null,"abstract":"<div><h3>Background</h3><div>The use of medicinal plants is widespread in traditional medicines worldwide, including in Morocco, where their use depends on cultural, economic, and geographical factors. This study aims to evaluate the frequency of use of medicinal plants among patients hospitalized at the University Hospital Center of Oujda and to identify the factors associated with it, as well as to examine the impact of the COVID-19 pandemic on this use.</div></div><div><h3>Methods</h3><div>A cross-sectional study, conducted from April 2022 to February 2023, was conducted in the cardiology, nephrology, internal medicine, neurology, oncology, and visceral surgery departments of the Mohammed VI University Hospital Center in Oujda. All adult patients (&gt; 18 years old), of both genders, who consented to participate in the study were included.</div></div><div><h3>Results</h3><div>307 patients were collected. The mean age of our patients was 52 ± 16 years, 57 % were female. 75.9 % of patients had already used medicinal plants and 46.5 % reported having consumed more during the COVID-19 pandemic. Digestive diseases, respiratory diseases, and cancer were among the main pathologies treated with these plants. The three main plants consumed were oregano in 54.7 % of cases, rosemary in 26.4 % of cases, and eucalyptus in 26.38 % of cases. The majority of patients (68.7 %) reported an improvement in their health status after consuming the plants, while 8.2 % of them had side effects, mainly gastrointestinal disorders. The consumption of plants was significantly associated with gender (p = 0.001), origin (p = 0.001) hospitalization department (p = 0.008) and history of cancer (p = 0.026).</div></div><div><h3>Conclusion</h3><div>This study highlights the importance of the use of medicinal plants in Morocco, especially during the COVID-19 pandemic, and emphasizes the need to act on the associated factors and to raise awareness among the population about their potential side effects.</div></div>","PeriodicalId":7343,"journal":{"name":"Advances in integrative medicine","volume":"12 3","pages":"Article 100487"},"PeriodicalIF":1.7,"publicationDate":"2025-04-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144480657","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Efficacy of Glycyrrhiza glabra on peptic ulcer disease: A systematic review and meta-analysis","authors":"Elham Zaeif Khorasani ,&nbsp;Tahereh Amirian ,&nbsp;Ebrahim Nasiri Formi ,&nbsp;Fatemeh Mahjoub ,&nbsp;Masoumeh Sadeghi","doi":"10.1016/j.aimed.2025.100485","DOIUrl":"10.1016/j.aimed.2025.100485","url":null,"abstract":"<div><h3>Introduction</h3><div>Peptic ulcer is a common gastrointestinal disorder, marked by lesions in the mucosal lining of the stomach and duodenum. Due to the limitations of conventional treatments, herbal medicines have gained wide popularity for treating digestive conditions. The current study aims to conduct a systematic review and meta-analysis to assess the effects of licorice on peptic ulcers.</div></div><div><h3>Methods</h3><div>A comprehensive search was performed in online databases, including PubMed, Web of Science, Scopus, Cochrane, and Embase, covering publications up to 7 August 2024, using relevant keywords. Ultimately, 9 studies, comprising a total of 618 participants, had the eligibility criteria. In the statistical analysis, binary data were analyzed using odds ratios (OR) with 95 % confidence intervals (CIs). To evaluate statistical heterogeneity across studies, the I2 statistic was calculated.</div></div><div><h3>Results</h3><div>These studies reported clinical improvement in peptic ulcer symptoms (stomach and duodenal ulcers) and radiographic and endoscopic evidence of complete healing lesion or reduction in size. Some of them demonstrated licorice’s positive effects on ulcer healing, while others found no significant difference compared to placebo. The pooled odds ratio for clinical symptom improvement in pain was calculated to be 0.52 (95 % CI: 0.42–1.45), and for complete ulcer healing, it was 0.60 (95 % CI: 0.24–1.43), indicating that these findings were not statistically significant.</div></div><div><h3>Conclusions</h3><div>While the intervention demonstrated a trend toward improved clinical symptoms and healing in peptic ulcers compared to placebo, the lack of statistical significance and the observed heterogeneity highlight the need for further research to clarify these effects</div></div>","PeriodicalId":7343,"journal":{"name":"Advances in integrative medicine","volume":"12 4","pages":"Article 100485"},"PeriodicalIF":1.7,"publicationDate":"2025-04-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144516981","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The effect of Shuneez (Nigella sativa) as galactogogue on mothers complaining of insufficient breast milk: A single-blind clinical trial","authors":"Samreen Khan ,&nbsp;M. Anas ,&nbsp;Diwan Israr Khan ,&nbsp;Deeba Khanam","doi":"10.1016/j.aimed.2025.100481","DOIUrl":"10.1016/j.aimed.2025.100481","url":null,"abstract":"<div><div>Despite the fact that exclusive breastfeeding has many health advantages for both mother and baby, only a small percentage of mothers actually adhere to this ideal practise leaving majority of infants without access to it. Most mothers (roughly 30–80 %) who stop exclusive breastfeeding for the first half year of baby's life complain about insufficient milk production. Therefore, this study was conducted on 100 mothers enrolled from Obstetrics and Paediatrics OPD of dept. of Amraze-Niswan wa Atfal Ajmal Khan Tibbiya College and Maternity Ward of Jawahar Lal Nehru Medical College, AMU, Aligarh from March 2021 to September 2022 on mothers complaining of insufficient breast milk secretion having child not more than a month in the absence of any systemic disease to the mother and her baby.The effect of the test drug on maternal serum prolactin and neonatal anthropometric measures (weight, length and head circumference) was significant with P &lt; 0.0001. Furthermore, it did not exert any adverse effect on maternal Hb, ALT, AST, ALP and S. creatinine (‘P’values 0.9178, 0.3146, 0.2242, 0.3282, 0.7320 respectively) and found safe on the above parameters.Therefore, it has been concluded from the study that the test drug <em>(Nigella sativa</em>) was effective and safe in enhancing breast milk secretion.</div></div>","PeriodicalId":7343,"journal":{"name":"Advances in integrative medicine","volume":"12 2","pages":"Article 100481"},"PeriodicalIF":1.7,"publicationDate":"2025-04-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144147284","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Yoga versus transdiagnostic cognitive behavioural therapy for emotional disorders in community-dwelling adults: Study protocol for a non-inferiority randomised controlled trial","authors":"Danielle C. Mathersul ,&nbsp;Jean M. Byrne ,&nbsp;Joyce J.Y. Lau ,&nbsp;Robert M. Schütze ,&nbsp;Yvonne C. Learmonth ,&nbsp;Hakuei Fujiyama ,&nbsp;Kristin Naragon-Gainey ,&nbsp;Peter M. McEvoy ,&nbsp;Peter J. Bayley","doi":"10.1016/j.aimed.2025.100484","DOIUrl":"10.1016/j.aimed.2025.100484","url":null,"abstract":"<div><div>Cognitive behavioural therapy (CBT) is the first-line non-pharmacological intervention for the most prevalent and co-occurring mental health conditions (anxiety, major depressive, posttraumatic stress, and alcohol use disorders). However, CBT response rates are variable and access is limited by cost, availability, and up-take. Yoga demonstrates efficacy for these conditions and may be more accessible than CBT. However, to better refine personalised healthcare and ensure maximum generalisability to “real-world” presentations, we need methodologically robust randomised controlled trials (RCTs) that compare yoga to appropriate controls, monitor mental health co-occurrences, and examine biomarkers and mechanisms of action alongside outcomes. We present the study protocol for an ongoing, experimenter-masked, parallel-group, non-inferiority design RCT to evaluate the efficacy of 10-week yoga (novel intervention) versus 10-week transdiagnostic CBT (the <em>Unified Protocol</em>; evidence-based active control) for co-occurring anxiety, major depressive, posttraumatic stress, or alcohol use disorders among community-dwelling Australian adults (aged ≥18 years). The protocol is approved by Murdoch University Human Research Ethics Committee. The primary outcome measure is the Kessler Psychological Distress Scale (weeks 0, 11, 23, 35) and power analyses determined a minimum of 67 participants per group are required to assess non-inferiority. Secondary outcomes include a clinician-administered interview, self-reported symptoms, and functional outcomes. Sleep and emotion regulation self-report measures (including ecological momentary assessment) and physiological biomarkers (actigraphy, heart rate variability) will be tested as potential moderators and mediators of outcome. Experimenter-masked analyses will use both intent-to-treat and per-protocol approaches.</div></div><div><h3>Findings</h3><div>will inform evidence-based formal recommendations and policy regarding the implementation of yoga into healthcare and may advance precision medicine.</div></div>","PeriodicalId":7343,"journal":{"name":"Advances in integrative medicine","volume":"12 3","pages":"Article 100484"},"PeriodicalIF":1.7,"publicationDate":"2025-04-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144491945","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Formulation, and clinical efficacy of Zataria multiflora Boiss. capsules in mild to moderate Alzheimer disease: A double-blind randomized trial","authors":"Mehdi Ansari ,&nbsp;Kosar Sargazi-Moghadam ,&nbsp;Haleh Tajadini ,&nbsp;Mohadese Kamali ,&nbsp;Hoda Kamali ,&nbsp;Tania Dehesh ,&nbsp;Reyhane Shojaei ,&nbsp;Fariba Sharififar","doi":"10.1016/j.aimed.2025.100483","DOIUrl":"10.1016/j.aimed.2025.100483","url":null,"abstract":"<div><h3>Objective</h3><div>Alzheimer’s disease (AD), the leading cause of dementia, is a major contributor to disability among older adults, and effective treatments remain a significant challenge. Recent studies suggest that <em>Zataria multiflora</em> has antioxidant, anticholinesterase, and memory-enhancing capabilities. This study investigates the potential of edible plant capsules derived from <em>Z. multiflora</em> to reduce clinical symptoms in patients with mild to moderate AD.</div></div><div><h3>Methods</h3><div>A randomized, double-blind, placebo-controlled clinical trial was conducted in a Kerman nursing home between November 2019 and February 2020. Herbal capsules were formulated using a standardized extract of <em>Z. multiflora</em> with rigorous quality control. Seventy-two eligible participants (over 50 years old) were randomly assigned to either the intervention or placebo groups using randomized replacement blocks. The intervention group received 600 mg of the herbal capsules three times daily, while the placebo group received an identical placebo, both for 8 weeks. The primary outcomes were memory improvements, measured using Clinical Dementia Rating (CDR) and Mini-Mental State Examination (MMSE) scores at baseline, week 4, and week 8. Data was analyzed using SPSS version 23 with independent t-tests, chi-square, and Fisher’s exact tests for group comparisons. A significance level of p &lt; 0.05 was used.</div></div><div><h3>Results</h3><div>Both groups showed statistically significant changes in mean CDR and MMSE scores from baseline to week 4, week 8, and also from week 4 to week 8. However, the intervention group had significantly greater improvements than the placebo group. A significant time-group interaction was observed in both CDR and MMSE assessments.</div></div><div><h3>Conclusion</h3><div>Despite the relatively short intervention period, which warrants further longer-term studies, the observed improvements in CDR and MMSE scores suggest that <em>Z. multiflora</em> may be a promising adjunctive treatment for individuals with AD. These findings support further research into the therapeutic potential of <em>Z. multiflora</em> in this context.</div></div>","PeriodicalId":7343,"journal":{"name":"Advances in integrative medicine","volume":"12 3","pages":"Article 100483"},"PeriodicalIF":1.7,"publicationDate":"2025-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144481198","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Standardization of herbal medicine use: A global imperative for safety, efficacy, and public health","authors":"Emad M. Abdallah,&nbsp;Wael E. Abdalla,&nbsp;Alaa M.M. Sadeek","doi":"10.1016/j.aimed.2025.100482","DOIUrl":"10.1016/j.aimed.2025.100482","url":null,"abstract":"","PeriodicalId":7343,"journal":{"name":"Advances in integrative medicine","volume":"12 4","pages":"Article 100482"},"PeriodicalIF":1.7,"publicationDate":"2025-03-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144518770","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Investigating the effects of applying low acoustic frequencies on the pain from venous and arterial blood sampling: A clinical trial study","authors":"Saeed Mohammadi ,&nbsp;Ebrahim Ezzati ,&nbsp;Rooghaye Mahooti ,&nbsp;Fatemeh Kavyannejad ,&nbsp;Mohammad Sadegh Paran ,&nbsp;Rasoul Kavyannejad","doi":"10.1016/j.aimed.2025.100480","DOIUrl":"10.1016/j.aimed.2025.100480","url":null,"abstract":"<div><h3>Background</h3><div>The pain of the blood sampling process is an unpleasant and common experience in the treatment process. Stimulation the thalamus structure and corticothalamic pathways with at specific frequencies could play a role in modulating pain perception. The aim of this study was to investigate the use low acoustic frequencies in reducing pain during arterial and venous blood sampling.</div></div><div><h3>Material and Methods</h3><div>In a triple-blinded clinical trial study, 300 patients in each process were randomly divided into control and intervention groups. Patients in the intervention groups received sound frequencies of 10–200 Hz with an intensity of 50 dB during the procedures. Pain intensity, heart rate changes, number of attempts for successful sampling, and time required for each procedure were measured. Data were analyzed using Prism 10 software.</div></div><div><h3>Results</h3><div>Pain levels were significantly lower in the intervention groups with increasing sound frequencies in both procedures (P &lt; 0.05). The duration of blood sampling procedures was significantly shorter with increasing sound frequency (P &lt; 0.05), but no difference was observed in the frequency of sampling attempts (P &gt; 0.05). By increasing the sound frequency, the intensity of tachycardia significantly decreased following the blood sampling process (P &lt; 0.05), especially at higher frequencies.</div></div><div><h3>Conclusion</h3><div>Applying low sound frequencies effectively could reduce acute pain and its consequences resulting from an invasive process. Sound frequencies appear to play a role in modulating pain pathways in the central nervous system.</div></div><div><h3>Implications for Clinical Practice</h3><div>The study findings suggest that sound frequency ranges as a non-pharmacological analgesia intervention can be used to reduce pain and discomfort following a variety of blood sampling procedures, which performed by nurses.</div></div>","PeriodicalId":7343,"journal":{"name":"Advances in integrative medicine","volume":"12 4","pages":"Article 100480"},"PeriodicalIF":1.7,"publicationDate":"2025-03-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144518768","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Efficacy of nutraceuticals in migraine symptoms relief: A systematic review and network meta-analysis","authors":"Imen Ketata ,&nbsp;Emna Ellouz","doi":"10.1016/j.aimed.2025.100478","DOIUrl":"10.1016/j.aimed.2025.100478","url":null,"abstract":"<div><h3>Background</h3><div>The effectiveness of nutraceuticals in alleviating migraine symptoms remains controversial, with ongoing debate among experts. This network meta-analysis (NMA) aims to compare the efficacy of various nutraceuticals on migraine symptoms relief.</div></div><div><h3>Methods</h3><div>A frequentist NMA was performed on double-blind randomized clinical trials involving migraine patients using NS. We searched PubMed, Europe PMC, Google Scholar, Web of Science, APA PsycInfo, gray literature, and systematic review references up to April 25, 2024. This NMA is registered in PROSPERO (CRD42024504214). Data analysis was conducted using R software, estimating the mean difference (MD) and 95 % CI for NS effects on migraine relief.</div></div><div><h3>Results</h3><div>twenty-five trials were reviewed. Compared to placebo, CoQ10 + L-carnitine (MD: −4.8 [95 % CI: −8.0; −1.7]), vitamin D3 (MD: −3.5 [95 %CI: −5.3; −1.6]), curcumin (MD: −6.0 [95 % CI: −10.7; −1.3]), and cinnamon (MD: −3.5 [95 % CI: −5.5; −1.1]) were ranked as the most effective NS for reducing monthly migraine frequency, migraine days duration/month, attack duration (hours), and migraine severity, respectively. Based on GRADE approach, the certainty of evidence was respectively low, moderate, low and high. The meta-regression revealed that follow-up duration significantly affected the impact of NS on MA/mo.</div></div><div><h3>Conclusion</h3><div>NS, particularly CoQ10 +L-carnitine, vitamin D3, curcumin, and cinnamon, may help reduce migraine symptoms. However, these findings are preliminary and require confirmation with higher-quality evidence. Additional research is needed to evaluate the combined effectiveness of these NS for migraine relief.</div></div>","PeriodicalId":7343,"journal":{"name":"Advances in integrative medicine","volume":"12 4","pages":"Article 100478"},"PeriodicalIF":1.7,"publicationDate":"2025-03-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144518771","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}