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Comparing the effects of yoga and exercise on vascular function: A systematic review 比较瑜伽和运动对血管功能的影响:一项系统综述
IF 1.7
Advances in integrative medicine Pub Date : 2025-07-15 DOI: 10.1016/j.aimed.2025.100556
Poovitha Shruthi Paramashiva , Suresh Sukumar , Dilip Shettigar , Rajagopal Kadavigere , Abhimanyu Pradhan , Nitika C. Panakkal , Winniecia Dkhar , K. Vaishali , Baskaran Chandrasekaran , Hari Prakash Palaniswamy , Sneha Ravichandran , Sathya Sabina Muthu , Koustubh Kamath , Haris Jose Felix , Anam Shazli , Leena R. David
{"title":"Comparing the effects of yoga and exercise on vascular function: A systematic review","authors":"Poovitha Shruthi Paramashiva ,&nbsp;Suresh Sukumar ,&nbsp;Dilip Shettigar ,&nbsp;Rajagopal Kadavigere ,&nbsp;Abhimanyu Pradhan ,&nbsp;Nitika C. Panakkal ,&nbsp;Winniecia Dkhar ,&nbsp;K. Vaishali ,&nbsp;Baskaran Chandrasekaran ,&nbsp;Hari Prakash Palaniswamy ,&nbsp;Sneha Ravichandran ,&nbsp;Sathya Sabina Muthu ,&nbsp;Koustubh Kamath ,&nbsp;Haris Jose Felix ,&nbsp;Anam Shazli ,&nbsp;Leena R. David","doi":"10.1016/j.aimed.2025.100556","DOIUrl":"10.1016/j.aimed.2025.100556","url":null,"abstract":"<div><h3>Background</h3><div>Sedentary behaviour negatively impacts vascular function, increasing cardiovascular risk. While yoga and conventional exercise are proposed to counteract these effects, their relative efficacy remains unclear.</div></div><div><h3>Objective</h3><div>This review aims to compare the effects of yoga and conventional exercise interventions on ultrasound-measured vascular function in sedentary individuals.</div></div><div><h3>Methods</h3><div>A systematic search of PubMed, Scopus, and Web of Science was conducted (last updated February 15, 2025), including randomized controlled trials (RCTs), crossover trials, and non-randomized studies comparing yoga and exercise interventions in sedentary adults. Studies assessing vascular function using ultrasound techniques (e.g., flow-mediated dilation [FMD], pulse wave velocity [PWV]) were included. The review followed PRISMA guidelines and was registered in PROSPERO (CRD420250655130).</div></div><div><h3>Results</h3><div>Ten studies met the inclusion criteria. Yoga interventions showed mixed results, with some improvement in endothelial function in older adults but inconsistent effects on arterial stiffness. Exercise interventions consistently improved FMD and reduced arterial stiffness. However, micro-breaks during prolonged sitting yielded limited benefits. Most studies had small sample sizes and short durations, affecting generalizability.</div></div><div><h3>Conclusion</h3><div>Exercise interventions consistently improve vascular function more than yoga among sedentary individuals. Yoga may benefit older populations but lacks</div></div>","PeriodicalId":7343,"journal":{"name":"Advances in integrative medicine","volume":"12 4","pages":"Article 100556"},"PeriodicalIF":1.7,"publicationDate":"2025-07-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144655656","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effects of compound Wuwei ironing pack combined with ERAS management mode on the recovery of gastrointestinal function after primary hepatocellular carcinoma surgery 复方五味熨烫包联合ERAS管理模式对原发性肝癌术后胃肠功能恢复的影响
IF 1.7
Advances in integrative medicine Pub Date : 2025-07-11 DOI: 10.1016/j.aimed.2025.100554
Jing Zou, Rao Fu, Lixia Zhang
{"title":"Effects of compound Wuwei ironing pack combined with ERAS management mode on the recovery of gastrointestinal function after primary hepatocellular carcinoma surgery","authors":"Jing Zou,&nbsp;Rao Fu,&nbsp;Lixia Zhang","doi":"10.1016/j.aimed.2025.100554","DOIUrl":"10.1016/j.aimed.2025.100554","url":null,"abstract":"<div><h3>Objective</h3><div>To evaluate the impact of the compound Wuwei ironing pack combined with the ERAS (Enhanced Recovery After Surgery) management protocol on postoperative gastrointestinal recovery in hepatocellular carcinoma patients.</div></div><div><h3>Methods</h3><div>A convenience sampling approach was used to recruit liver cancer patients from the hepatobiliary and pancreatic surgery ward of our hospital between June 2023 and February 2024. A total of 159 patients were randomized into three groups: (1) the control group, which received standard ERAS management; (2) the fennel ironing pack group, which used an independent fennel-based physiotherapy formula; and (3) the compound Wuwei ironing pack group, which utilized a physiotherapy pack developed by the Traditional Chinese Medicine Department. This pack contained five traditional Chinese herbs: fennel, dried tangerine peel, Fructus Aurantii Immaturus, Magnoliae Officinalis Cortex, and malt. The groups were compared based on time to first defecation, length of hospital stay, incidence of infection, and nutritional indicators.</div></div><div><h3>Results</h3><div>The compound Wuwei ironing pack group demonstrated significantly shorter time to first defecation and postoperative hospital stay compared to the fennel group and the control group (both P &lt; 0.05).</div></div><div><h3>Conclusion</h3><div>The compound Wuwei traditional Chinese medicine ironing pack demonstrated better recovery outcomes compared to fennel physiotherapy and standard ERAS management. It reduced hospital stay, is simple to use, safe, and suitable for clinical application.</div></div>","PeriodicalId":7343,"journal":{"name":"Advances in integrative medicine","volume":"12 4","pages":"Article 100554"},"PeriodicalIF":1.7,"publicationDate":"2025-07-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144631276","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Exploring the health and biochemical effects of kratom (Mitragyna speciosa) consumption within the local community of Putussibau district, Borneo, Indonesia 在印度尼西亚婆罗洲Putussibau地区的当地社区,探索食用kratom (Mitragyna speciosa)对健康和生化的影响
IF 1.7
Advances in integrative medicine Pub Date : 2025-07-11 DOI: 10.1016/j.aimed.2025.100555
Mery Budiarti , Lusi Kristiana , Pramita Andarwati , Aris Yulianto , Rohmat Mujahid , Slamet Wahyono , Zulvikar Syambani Ulhaq
{"title":"Exploring the health and biochemical effects of kratom (Mitragyna speciosa) consumption within the local community of Putussibau district, Borneo, Indonesia","authors":"Mery Budiarti ,&nbsp;Lusi Kristiana ,&nbsp;Pramita Andarwati ,&nbsp;Aris Yulianto ,&nbsp;Rohmat Mujahid ,&nbsp;Slamet Wahyono ,&nbsp;Zulvikar Syambani Ulhaq","doi":"10.1016/j.aimed.2025.100555","DOIUrl":"10.1016/j.aimed.2025.100555","url":null,"abstract":"<div><h3>Background</h3><div><em>Mitragyna speciosa</em> Korth, commonly known as kratom, is a native medicinal plant of Southeast Asia, including Indonesia, known for its opioid-like effects. The traditional brewing of kratom has been a longstanding folk remedy, especially within the local community in Indonesia. Our study aims to evaluate the health and biochemical impacts of kratom consumption among regular users in the local community of Putussibau District, Kapuas Hulu Regency, Borneo, Indonesia.</div></div><div><h3>Methods</h3><div>A total of 75 participants were involved in this cross-sectional study. All surveys were carried out through face-to-face interviews to gather information on participants' sociodemographic characteristics and their history of kratom use. Clinical chemistry analysis (n = 60 participants) was then performed to assess potential alterations in the biochemical parameters of kratom users.</div></div><div><h3>Results</h3><div>The majority of participants perceived that kratom consumption positively influenced their overall health status. However, these perceived benefits may not consistently supported by corresponding biochemical findings. Kratom users showed an inclination towards elevated LDL and TG levels compared to the reference levels (73 % (44/60) and 58 % (35/60) of the total participants, respectively), as well as increased hs-CRP (62 % (36/60) of the total participants). Notably, individuals consuming higher doses of kratom tended to have a higher BUN levels.</div></div><div><h3>Conclusion</h3><div>In summary, our study suggests that, in general, individuals who regularly consume brewed kratom over an extended period did not experience undesirable effects. Nevertheless, it is crucial to highlight the potential adverse effects of kratom consumption, including alterations in lipid profile, kidney function, and inflammatory response.</div></div>","PeriodicalId":7343,"journal":{"name":"Advances in integrative medicine","volume":"12 4","pages":"Article 100555"},"PeriodicalIF":1.7,"publicationDate":"2025-07-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144662394","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The relationship between caffeine consumption and self-reported sleep quality among healthcare professionals 保健专业人员咖啡因摄入量与自我报告睡眠质量之间的关系
IF 1.7
Advances in integrative medicine Pub Date : 2025-07-11 DOI: 10.1016/j.aimed.2025.100553
Sedat Arslan , Kevser TARI Selcuk , Kübra Betül Kirbiyik , Nuh Şerbetçi̇
{"title":"The relationship between caffeine consumption and self-reported sleep quality among healthcare professionals","authors":"Sedat Arslan ,&nbsp;Kevser TARI Selcuk ,&nbsp;Kübra Betül Kirbiyik ,&nbsp;Nuh Şerbetçi̇","doi":"10.1016/j.aimed.2025.100553","DOIUrl":"10.1016/j.aimed.2025.100553","url":null,"abstract":"<div><h3>Objective</h3><div>This study aims to examine the relationship between caffeine consumption and sleep quality among healthcare professionals.</div></div><div><h3>Method</h3><div>This cross-sectional study was conducted on 98 healthcare professionals working at Balıkesir Havran State Hospital. Participants' caffeine consumption levels were assessed using the Caffeine Consumption Frequency Questionnaire, and their sleep quality was evaluated using the Pittsburgh Sleep Quality Index (PSQI). The data were analyzed using the SPSS 22.0 statistical software package. Descriptive statistics, student’s t-test, and linear regression analyses were performed, with a significance level set at p &lt; 0.05.</div></div><div><h3>Results</h3><div>The average daily caffeine consumption among participants was found to be 279.12 ± 168.50 mg. Although the mean caffeine intake was slightly higher among females, this difference was not statistically significant. 57.1 % of the participants were evaluated as having poor sleep quality. According to the regression analysis, daily caffeine consumption was positively associated with sleep duration (p &lt; 0.05), but no significant relationship was found with other components of sleep quality.</div></div><div><h3>Conclusion</h3><div>This study suggests that daily caffeine consumption among healthcare professionals may have a positive effect on sleep duration, but does not have a significant impact on overall sleep quality.</div></div>","PeriodicalId":7343,"journal":{"name":"Advances in integrative medicine","volume":"12 4","pages":"Article 100553"},"PeriodicalIF":1.7,"publicationDate":"2025-07-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144631275","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Anthropometric indices correlates of temperament (Mizaj) in traditional medicine: A cross-sectional study of Iranian males 传统医学中与气质(Mizaj)相关的人体测量指数:伊朗男性的横断面研究
IF 1.7
Advances in integrative medicine Pub Date : 2025-06-30 DOI: 10.1016/j.aimed.2025.100536
Soheil Ashouri , Mohammad Mahdi Ahmadian-Attari , Malihe Farid , Hamid Shamsi Baghbanan , Simin Mahakizadeh
{"title":"Anthropometric indices correlates of temperament (Mizaj) in traditional medicine: A cross-sectional study of Iranian males","authors":"Soheil Ashouri ,&nbsp;Mohammad Mahdi Ahmadian-Attari ,&nbsp;Malihe Farid ,&nbsp;Hamid Shamsi Baghbanan ,&nbsp;Simin Mahakizadeh","doi":"10.1016/j.aimed.2025.100536","DOIUrl":"10.1016/j.aimed.2025.100536","url":null,"abstract":"<div><div>Traditional Iranian medicine classifies individuals based on temperament (Mizaj), defined by hot-cold and dry-wet attributes, which are thought to influence health and disease susceptibility. This study investigates the relationship between temperaments and anthropometric variables, aiming to provide a quantitative, evidence-based foundation for traditional medicine. A cross-sectional study conducted with 200 healthy males aged 20–30. We recorded a number of anthropometric measurements, including height, weight, skinfold thickness, and hip (HC) and waist (WC) circumferences. Body Mass Index (BMI) and body fat index (BFI) were calculated. Participants completed a validated temperament assessment questionnaire. Participants were categorized into four groups: Warm-Dry (WD) (28 %), Warm-Wet (WW) (18 %), Cold-Dry (CD) (17.3 %), and Cold-Wet (CW) (36.7 %). Significant differences were observed in weight, BMI, BFI, waist, and hip circumferences among the groups. The CW group had the highest average weight (88.35 kg), BFI (25.1 %), BMI (27.93 kg/m²), while the WD group had the lowest weight (69.39 kg), BMI (21.13 kg/m²), BFI (14.8 %), ROC curve analysis identified pelvic circumference as the optimal predictor for cold-warm temperament classification, with a cut-off value of 99.5 cm, for dry-wet temperament, BFI was the reasonable predictor, with a cut-off of 20.10 %. The findings are consistent with traditional Iranian medicine principles, which associate warm-wet temperaments with larger body sizes and greater soft tissue mass, while cold or dry temperaments correlate with a leaner physique. These findings support the using anthropometric indices as objective measures for temperament classification, offering a scientific basis for traditional Iranian medicine and enhancing personalized health interventions.</div></div>","PeriodicalId":7343,"journal":{"name":"Advances in integrative medicine","volume":"12 4","pages":"Article 100536"},"PeriodicalIF":1.7,"publicationDate":"2025-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144631272","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Exploring the role of traditional medicine in complementary management for sexually transmitted diseases (STDs) 探讨传统医学在性传播疾病辅助管理中的作用
IF 1.7
Advances in integrative medicine Pub Date : 2025-06-26 DOI: 10.1016/j.aimed.2025.100531
Amit Anand , Santhepete Nanjundiah. Manjula , Mruthunjaya Kenganora , Subhajit Mandal , Himanshu Sharma , Rashmi Pathak
{"title":"Exploring the role of traditional medicine in complementary management for sexually transmitted diseases (STDs)","authors":"Amit Anand ,&nbsp;Santhepete Nanjundiah. Manjula ,&nbsp;Mruthunjaya Kenganora ,&nbsp;Subhajit Mandal ,&nbsp;Himanshu Sharma ,&nbsp;Rashmi Pathak","doi":"10.1016/j.aimed.2025.100531","DOIUrl":"10.1016/j.aimed.2025.100531","url":null,"abstract":"&lt;div&gt;&lt;h3&gt;Background&lt;/h3&gt;&lt;div&gt;Sexually Transmitted Disease (STDs) remain a significant global health issue, particularly affecting women due to biological and sociocultural factors. Traditional medicine has been widely used in the management of sexually transmitted disease due to its accessibility, affordability and cultural acceptance. However, it has several limitations that challenge its efficacy and reliability due to absence of rigorous scientific validation and clinical trials. The study was undertaken to explore the integration of traditional medicine with modern approaches to STD management. The purpose of the review to bridge the gap in knowledge between traditional medicinal practices and modern interventions through a comparative analysis. It also aims to address the gaps in healthcare access, particularly in underprivileged regions where economic constraints limit the availability of conventional allopathic treatments.&lt;/div&gt;&lt;/div&gt;&lt;div&gt;&lt;h3&gt;Methods&lt;/h3&gt;&lt;div&gt;The study employed systematic literature review methodology to explore the application of traditional medicine in STD management. Databases such as Pub Med, Google scholar, science direct, web of science was searched from up to January 2024. Search terms included “traditional medicine, “STDs”, “medicinal plants” and specific plant names (eg: Neem, Echinea, &lt;em&gt;Aloe vera&lt;/em&gt;). A total of 381 articles were initially retrieved and duplicates were removed. Inclusion criteria focused on studies providing &lt;em&gt;in-vitro&lt;/em&gt; and &lt;em&gt;in-vivo&lt;/em&gt; data for STD treatment, cultural applications and integration with modern medicine. Relevant were extracted using a structural database, capturing the plant species, active compounds, mechanisms of action and therapeutic outcomes. Cross referencing with WHO and national databases ensured the inclusion of the latest prevalence and management.&lt;/div&gt;&lt;/div&gt;&lt;div&gt;&lt;h3&gt;Results&lt;/h3&gt;&lt;div&gt;The findings suggest practice of traditional medicines including the use of specific plants and holistic approaches offers valuable benefits in the management of STDs and enhancing overall wellbeing. The integration of traditional medicine with modern health practices provides a comprehensive approach that addresses not only the physical aspects of health but also the emotional and social dimension. The limitations of the findings presented in the review primarily stem from the limited number of clinical trials included. Such studies primarily elucidate theoretical mechanisms of action and biological pathways. However, these results cannot be directly extrapolated to clinical outcomes or therapeutic benefits in human populations, highlighting the need for caution when interpreting the transitional potential of these findings.&lt;/div&gt;&lt;/div&gt;&lt;div&gt;&lt;h3&gt;Discussion&lt;/h3&gt;&lt;div&gt;The review highlights the importance of combine approach of traditional medicine with modern clinical practices to create an inclusive and culturally sensitive approach to STD management and female health. The signi","PeriodicalId":7343,"journal":{"name":"Advances in integrative medicine","volume":"12 4","pages":"Article 100531"},"PeriodicalIF":1.7,"publicationDate":"2025-06-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144501060","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Ethnopharmacology of Calotropis procera: Traditional knowledge and scientific insights from Dodoma Region, Tanzania 原花椒的民族药理学:来自坦桑尼亚Dodoma地区的传统知识和科学见解
IF 1.7
Advances in integrative medicine Pub Date : 2025-06-26 DOI: 10.1016/j.aimed.2025.100535
Hamisi Yunus Nchimbi
{"title":"Ethnopharmacology of Calotropis procera: Traditional knowledge and scientific insights from Dodoma Region, Tanzania","authors":"Hamisi Yunus Nchimbi","doi":"10.1016/j.aimed.2025.100535","DOIUrl":"10.1016/j.aimed.2025.100535","url":null,"abstract":"<div><h3>Introduction</h3><div>This study explored the integration of traditional knowledge and contemporary science in the ethnopharmacology of <em>Calotropis procera</em> in the Kongwa District, Dodoma region in Tanzania.</div></div><div><h3>Method</h3><div>A cross-sectional design combining qualitative interviews with 110 respondents from Lenjulu and Majawanga villages, alongside laboratory analyses, was employed. These included preliminary phytochemical screening, GC–MS complemented by LC-MS, and in vitro antimicrobial assays using the microdilution method in 96-well microtiter plates.</div></div><div><h3>Results</h3><div>Ethnobotanical data revealed that traditional knowledge of <em>C. procera</em> is predominantly held by older community members, with 41.8 % of respondents above 55 years, and is transmitted mainly through intergenerational transfer, apprenticeships, and gender-specific roles. Phytochemical screening confirmed the presence of key bioactive compounds such as phenols, flavonoids, alkaloids, tannins, saponins, terpenoids, and steroids, validating its traditional use in treating ailments. The chemical profiling of <em>C. procera</em> using LC-MS and GC-MS revealed several dominant bioactive compounds across multiple pharmacological classes. For example, LC-MS analysis identified amino acids L-Tyrosine (12.73 %) and L-Isoleucine (8.92 %) and a flavonoid Quercetin (9.65 %), indicating their abundance and potential biological significance. GC-MS results highlighted a sesquiterpene Caryophyllene (8.12 %)<strong>,</strong> a diterpene Neophytadiene (4.92 %) and a triterpenoid Squalene (3.56 %), all are known for anti-inflammatory and antimicrobial activities. These findings underscore the phytochemical richness and therapeutic potential of <em>C. procera</em>. In vitro antimicrobial assays revealed pronounced antibacterial efficacy of the <em>C. procera</em>, with B.subtilis exhibiting the highest susceptibility (MIC: 7.03 mg/L), followed by S.typhi (MIC: 14.06 mg/L), E.coli (MIC: 28.13 mg/L), and S.aureus (MIC: 56.25 mg/L). The observed activity is attributed to the presence of bioactive phytochemical constituents, underscoring the plant’s ethnopharmacological relevance as a promising source of natural antibacterial compounds.</div></div><div><h3>Conclusion</h3><div>These findings support the therapeutic potential of <em>C. procera and underscore the critical need to preserve traditional medical knowledge for future healthcare applications.</em></div></div><div><h3>Take-home message</h3><div>Preserving the traditional knowledge of <em>C. procera</em> in Kongwa District is essential for future pharmaceutical and medical breakthroughs, as scientific validation has confirmed its strong antibacterial properties.</div></div>","PeriodicalId":7343,"journal":{"name":"Advances in integrative medicine","volume":"12 4","pages":"Article 100535"},"PeriodicalIF":1.7,"publicationDate":"2025-06-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144516992","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A scoping review exploring the role of homoeopathic drugs as a host directed therapy in the management of drug-resistant tuberculosis 一篇探讨顺势疗法药物作为宿主定向治疗在耐药结核病管理中的作用的综述
IF 1.7
Advances in integrative medicine Pub Date : 2025-06-26 DOI: 10.1016/j.aimed.2025.100533
Bhargav Sarma K , Vaishali Vasant Dolas , Vijay Nema
{"title":"A scoping review exploring the role of homoeopathic drugs as a host directed therapy in the management of drug-resistant tuberculosis","authors":"Bhargav Sarma K ,&nbsp;Vaishali Vasant Dolas ,&nbsp;Vijay Nema","doi":"10.1016/j.aimed.2025.100533","DOIUrl":"10.1016/j.aimed.2025.100533","url":null,"abstract":"<div><h3>Introduction</h3><div>Host-directed therapies (HDTs) for tuberculosis are being investigated. By regulating host cell factors, especially in conditions like Drug-resistant tuberculosis, the increasing burden of Anti-Microbial Resistance (AMR) can be reduced. The role of homoeopathic drugs or CAM (complementary and alternative medicine) drugs in regulating host-directed mechanisms is largely unknown. The primary objective of this scoping review is to identify the host-directed mechanisms of homoeopathic drugs in relation to Mycobacterium tuberculosis pathophysiology. The second objective is to understand whether these host-directed mechanisms can be useful for treating sensitive and drug-resistant tuberculosis.</div></div><div><h3>Methods</h3><div>Our scoping review was drafted using the PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) extension for scoping reviews. The following databases were searched to identify potentially relevant papers: PUBMED, COCHRANE, AYUSH RESEARCH PORTAL, and Google SCHOLAR. Forty-eight papers were screened by two people independently with blinding using Rayyan.</div></div><div><h3>Results</h3><div>The number of papers identified from databases and registers was 82. Only 15 papers were included in the final selection, while others were excluded because they did not meet the criteria for homoeopathy, host-directed mechanisms, and drug-resistant tuberculosis.</div></div><div><h3>Discussion</h3><div>To be considered host-directed, a homoeopathic drug action must act through the following mechanisms: regulation of adaptive immune responses, innate immune responses, cell death targets, and metabolism regulation. If we analyse the studies taken for review, we may find that some homoeopathic drugs regulate cytokines, matrix metalloproteinases (MMPs), Phosphofructokinase and other mechanisms. These experiments demonstrate that homoeopathic drugs act through host-directed mechanisms, but there is a lack of research papers on sensitive and drug-resistant tuberculosis.</div></div><div><h3>Conclusion</h3><div>So this concludes that in this review we were able to achieve only one objective which is the action of homoeopathic drugs through the host-directed mechanism, further research with In Vitro or In Vivo models can help us to complete our second objective.</div></div>","PeriodicalId":7343,"journal":{"name":"Advances in integrative medicine","volume":"12 4","pages":"Article 100533"},"PeriodicalIF":1.7,"publicationDate":"2025-06-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144518772","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effects of art therapy interventions on satisfaction with life: A systematic review and meta-analysis 艺术治疗干预对生活满意度的影响:一项系统回顾和荟萃分析
IF 1.7
Advances in integrative medicine Pub Date : 2025-06-25 DOI: 10.1016/j.aimed.2025.100532
Javier Fernández-Sánchez , Daniel Trujillo-Colmena , Daniel Collado-Mateo , Juan Luis Leon-Llamas , Ana Myriam Lavín-Pérez , Miriam Lorenzo-González
{"title":"Effects of art therapy interventions on satisfaction with life: A systematic review and meta-analysis","authors":"Javier Fernández-Sánchez ,&nbsp;Daniel Trujillo-Colmena ,&nbsp;Daniel Collado-Mateo ,&nbsp;Juan Luis Leon-Llamas ,&nbsp;Ana Myriam Lavín-Pérez ,&nbsp;Miriam Lorenzo-González","doi":"10.1016/j.aimed.2025.100532","DOIUrl":"10.1016/j.aimed.2025.100532","url":null,"abstract":"<div><div>Art therapies have emerged as a cost-effective global resource for promoting wellbeing, and quality of life and for reducing mental health problems through mind-body connection and creative expression. The aim was to systematically review the current evidence about the benefits of dance and theater-based interventions on the life satisfaction of participants. Furthermore, this study is aimed to synthesize and meta-analyze the results of the previously published randomized controlled trials. Thus, to identify the articles, a systematic search was conducted in PubMed (Medline) and Web of Science. The inclusion criteria included: being a randomized controlled trial, evaluating the effects of dance or drama interventions and providing pre-post data showing the effects on life satisfaction. A total of 12 articles were included in the Systematic Review, with 8 of them being included in the meta-analysis. Meta-analysis results showed that dance and drama interventions are effective (p = 0.01) in increasing the satisfaction with life of participants with different ages and conditions. In conclusion, dance and theater-based interventions are two forms of art therapies that may be useful to enhance the life satisfaction of people. Furthermore, further studies are needed to make stronger evidence-based recommendations or comparisons to other types of physical activity.</div></div>","PeriodicalId":7343,"journal":{"name":"Advances in integrative medicine","volume":"12 4","pages":"Article 100532"},"PeriodicalIF":1.7,"publicationDate":"2025-06-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144516980","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Investigation of attitudes of hypertension patients toward holistic complementary and alternative medicine 高血压患者对整体补充替代医学的态度调查
IF 1.7
Advances in integrative medicine Pub Date : 2025-06-24 DOI: 10.1016/j.aimed.2025.100534
Zeliha Buyukbayram Genc , Seyhan Citlik Saritas
{"title":"Investigation of attitudes of hypertension patients toward holistic complementary and alternative medicine","authors":"Zeliha Buyukbayram Genc ,&nbsp;Seyhan Citlik Saritas","doi":"10.1016/j.aimed.2025.100534","DOIUrl":"10.1016/j.aimed.2025.100534","url":null,"abstract":"<div><h3>Background</h3><div>Hypertension is one of the most common cardiovascular diseases.</div></div><div><h3>Purpose</h3><div>This study was conducted to examine the attitudes of patients diagnosed with hypertension toward holistic complementary and alternative medicine.</div></div><div><h3>Method</h3><div>This descriptive and cross-sectional study was carried out with 230 adult patients diagnosed with hypertension who applied to the internal medicine and cardiology outpatient clinics of a Training and Research Hospital. Data were collected using the Personal Information Form and the Attitude Scale towards Holistic Complementary and Alternative Medicine. Data were analyzed with descriptive statistics, independent groups t-test, Kruskal-Wallis, and ANOVA tests. In addition, the Dunn-Bonferroni test was used to determine the difference between groups.</div></div><div><h3>Results</h3><div>The study revealed that the mean age of the patients was 54.36 ± 13.09, while 59.1 % were women, 81.3 % were married, 27.4 % were literate, and 61.3 % were unemployed. Also, it was observed that 41.3 % of the patients were diagnosed with hypertension between 1 and 5 years, 58.7 % had no other chronic illnesses, and 60.0 % had a family hypertension history. Additionally, 77.0 % of the patients used CAM, 24.9 % got information from the Internet/media via CAM, 27.1 % used CAM in addition to medical treatment, 56.5 % found CAM methods safe, 38.4 % used herbal agents, 76.3 % It has been determined that ten of them benefit from the use of CAM. The patients’ total mean score participating in the study in HCAMQ was 28.80 ± 6.73.</div></div><div><h3>Conclusion</h3><div>It was determined that the patients' attitudes toward CAM were positive and moderate. Additionally, the findings disclosed that the education level of the patients affected their use of CAM, their benefit from CAM, and their attitudes towards CAM.</div></div>","PeriodicalId":7343,"journal":{"name":"Advances in integrative medicine","volume":"12 4","pages":"Article 100534"},"PeriodicalIF":1.7,"publicationDate":"2025-06-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144518769","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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