{"title":"研究应用低频率对静脉和动脉采血疼痛的影响:一项临床试验研究","authors":"Saeed Mohammadi , Ebrahim Ezzati , Rooghaye Mahooti , Fatemeh Kavyannejad , Mohammad Sadegh Paran , Rasoul Kavyannejad","doi":"10.1016/j.aimed.2025.100480","DOIUrl":null,"url":null,"abstract":"<div><h3>Background</h3><div>The pain of the blood sampling process is an unpleasant and common experience in the treatment process. Stimulation the thalamus structure and corticothalamic pathways with at specific frequencies could play a role in modulating pain perception. The aim of this study was to investigate the use low acoustic frequencies in reducing pain during arterial and venous blood sampling.</div></div><div><h3>Material and Methods</h3><div>In a triple-blinded clinical trial study, 300 patients in each process were randomly divided into control and intervention groups. Patients in the intervention groups received sound frequencies of 10–200 Hz with an intensity of 50 dB during the procedures. Pain intensity, heart rate changes, number of attempts for successful sampling, and time required for each procedure were measured. Data were analyzed using Prism 10 software.</div></div><div><h3>Results</h3><div>Pain levels were significantly lower in the intervention groups with increasing sound frequencies in both procedures (P < 0.05). The duration of blood sampling procedures was significantly shorter with increasing sound frequency (P < 0.05), but no difference was observed in the frequency of sampling attempts (P > 0.05). By increasing the sound frequency, the intensity of tachycardia significantly decreased following the blood sampling process (P < 0.05), especially at higher frequencies.</div></div><div><h3>Conclusion</h3><div>Applying low sound frequencies effectively could reduce acute pain and its consequences resulting from an invasive process. Sound frequencies appear to play a role in modulating pain pathways in the central nervous system.</div></div><div><h3>Implications for Clinical Practice</h3><div>The study findings suggest that sound frequency ranges as a non-pharmacological analgesia intervention can be used to reduce pain and discomfort following a variety of blood sampling procedures, which performed by nurses.</div></div>","PeriodicalId":7343,"journal":{"name":"Advances in integrative medicine","volume":"12 4","pages":"Article 100480"},"PeriodicalIF":1.7000,"publicationDate":"2025-03-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Investigating the effects of applying low acoustic frequencies on the pain from venous and arterial blood sampling: A clinical trial study\",\"authors\":\"Saeed Mohammadi , Ebrahim Ezzati , Rooghaye Mahooti , Fatemeh Kavyannejad , Mohammad Sadegh Paran , Rasoul Kavyannejad\",\"doi\":\"10.1016/j.aimed.2025.100480\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><h3>Background</h3><div>The pain of the blood sampling process is an unpleasant and common experience in the treatment process. Stimulation the thalamus structure and corticothalamic pathways with at specific frequencies could play a role in modulating pain perception. The aim of this study was to investigate the use low acoustic frequencies in reducing pain during arterial and venous blood sampling.</div></div><div><h3>Material and Methods</h3><div>In a triple-blinded clinical trial study, 300 patients in each process were randomly divided into control and intervention groups. Patients in the intervention groups received sound frequencies of 10–200 Hz with an intensity of 50 dB during the procedures. Pain intensity, heart rate changes, number of attempts for successful sampling, and time required for each procedure were measured. Data were analyzed using Prism 10 software.</div></div><div><h3>Results</h3><div>Pain levels were significantly lower in the intervention groups with increasing sound frequencies in both procedures (P < 0.05). The duration of blood sampling procedures was significantly shorter with increasing sound frequency (P < 0.05), but no difference was observed in the frequency of sampling attempts (P > 0.05). By increasing the sound frequency, the intensity of tachycardia significantly decreased following the blood sampling process (P < 0.05), especially at higher frequencies.</div></div><div><h3>Conclusion</h3><div>Applying low sound frequencies effectively could reduce acute pain and its consequences resulting from an invasive process. Sound frequencies appear to play a role in modulating pain pathways in the central nervous system.</div></div><div><h3>Implications for Clinical Practice</h3><div>The study findings suggest that sound frequency ranges as a non-pharmacological analgesia intervention can be used to reduce pain and discomfort following a variety of blood sampling procedures, which performed by nurses.</div></div>\",\"PeriodicalId\":7343,\"journal\":{\"name\":\"Advances in integrative medicine\",\"volume\":\"12 4\",\"pages\":\"Article 100480\"},\"PeriodicalIF\":1.7000,\"publicationDate\":\"2025-03-28\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Advances in integrative medicine\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S2212958825000394\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q2\",\"JCRName\":\"Medicine\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Advances in integrative medicine","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S2212958825000394","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"Medicine","Score":null,"Total":0}
Investigating the effects of applying low acoustic frequencies on the pain from venous and arterial blood sampling: A clinical trial study
Background
The pain of the blood sampling process is an unpleasant and common experience in the treatment process. Stimulation the thalamus structure and corticothalamic pathways with at specific frequencies could play a role in modulating pain perception. The aim of this study was to investigate the use low acoustic frequencies in reducing pain during arterial and venous blood sampling.
Material and Methods
In a triple-blinded clinical trial study, 300 patients in each process were randomly divided into control and intervention groups. Patients in the intervention groups received sound frequencies of 10–200 Hz with an intensity of 50 dB during the procedures. Pain intensity, heart rate changes, number of attempts for successful sampling, and time required for each procedure were measured. Data were analyzed using Prism 10 software.
Results
Pain levels were significantly lower in the intervention groups with increasing sound frequencies in both procedures (P < 0.05). The duration of blood sampling procedures was significantly shorter with increasing sound frequency (P < 0.05), but no difference was observed in the frequency of sampling attempts (P > 0.05). By increasing the sound frequency, the intensity of tachycardia significantly decreased following the blood sampling process (P < 0.05), especially at higher frequencies.
Conclusion
Applying low sound frequencies effectively could reduce acute pain and its consequences resulting from an invasive process. Sound frequencies appear to play a role in modulating pain pathways in the central nervous system.
Implications for Clinical Practice
The study findings suggest that sound frequency ranges as a non-pharmacological analgesia intervention can be used to reduce pain and discomfort following a variety of blood sampling procedures, which performed by nurses.
期刊介绍:
Advances in Integrative Medicine (AIMED) is an international peer-reviewed, evidence-based research and review journal that is multi-disciplinary within the fields of Integrative and Complementary Medicine. The journal focuses on rigorous quantitative and qualitative research including systematic reviews, clinical trials and surveys, whilst also welcoming medical hypotheses and clinically-relevant articles and case studies disclosing practical learning tools for the consulting practitioner. By promoting research and practice excellence in the field, and cross collaboration between relevant practitioner groups and associations, the journal aims to advance the practice of IM, identify areas for future research, and improve patient health outcomes. International networking is encouraged through clinical innovation, the establishment of best practice and by providing opportunities for cooperation between organisations and communities.