Food frontiers最新文献

{"title":"How Flavorsome Was That Movie? Using a Bayesian Network Approach to Understand How Audiovisual Stimuli Influence Emotions and Flavor Perception","authors":"Yi Hsuan Tiffany Lin,&nbsp;Daniel Shepherd,&nbsp;Kevin Kantono,&nbsp;Yifan Dai,&nbsp;Nazimah Hamid","doi":"10.1002/fft2.70011","DOIUrl":"https://doi.org/10.1002/fft2.70011","url":null,"abstract":"<p>This study utilized the temporal check-all-that-apply (TCATA) approach to investigate the impact of viewing video clips on the perception of ice cream. The association between subjectively rated emotions and their electrophysiological correlates was further explored using Bayesian network (BN) modelling. Participants consumed chocolate ice cream under different video conditions, and sweetness, bitterness, milkiness, creaminess, cocoa flavor, and roasted flavor ratings were acquired using the TCATA approach. Additionally, electrophysiological measurements of heart rate (HR), skin conductance (SC), and blood volume pulse (BVP) amplitude were obtained. The results showed that videos that evoked pleasant emotions, such as enjoyment and relaxation, were associated with increased ratings of sweetness and creaminess. Conversely, videos that evoked negative feelings, such as stress, were linked to higher ratings of bitterness. Furthermore, changes in electrophysiological measures were consistent with the variety of affective states evoked by the videos. Arousing videos increased HR and SC, while videos that induced calmness had the opposite effect. The use of BN modelling revealed significant relationships between affective states and electrophysiological responses with flavor perception. The model demonstrated that HR and SC were positively correlated with positive emotions that contributed to the perception of sweetness and milkiness, respectively. On the other hand, BVP amplitude was negatively correlated with arousal and perceptions of cocoa. Additionally, ratings of ‘quiet’ and ‘excited’ emotions were positively correlated to creaminess, while tension was positively correlated to roasted flavor. These findings indicate that understanding the impact of emotions on food perception can facilitate the design of consumer experiences that enhance enjoyment and engagement with food products.</p>","PeriodicalId":73042,"journal":{"name":"Food frontiers","volume":"6 3","pages":"1323-1342"},"PeriodicalIF":7.4,"publicationDate":"2025-04-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/fft2.70011","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144140808","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Interplay Between Auction Conditions and Mackerel (Scomber japonicus) Quality: Insights Into the Impact of Climatic Variations on the Mackerel Attributes","authors":"Seul-Ki Park,&nbsp;Su-Jeong Lee,&nbsp;Du-Min Jo,&nbsp;Sung-Hwan Eom,&nbsp;Kyung-Tae Kim,&nbsp;Won Je Jang,&nbsp;Eun-Song Kim,&nbsp;Sung Bum Son,&nbsp;Kee-Jai Park,&nbsp;Eun-Woo Lee","doi":"10.1002/fft2.70025","DOIUrl":"https://doi.org/10.1002/fft2.70025","url":null,"abstract":"<p>Climate change significantly impacts the food industry, particularly affecting seafood quality and freshness due to temperature changes. This study aimed to track mackerel quality indicators at auction sites and assess the impact of weather changes on its quality and freshness. During the summer, acid value (AV) varied from 0.70 ± 0.19 to 3.61 ± 0.52 mg/kg, while the peroxide value (POV) in the 300-g mackerel group ranged from 4.8 to 7.09 meq/kg. This group also exhibited volatile base nitrogen (VBN) values exceeding 25 mg/100 g as the auction progressed. Total bacterial counts (TBC) increased beyond 4 log₁₀ CFU/g, indicating that microbiological contamination would reach the initial spoilage level by the end of the auction. Temperature and season significantly (<i>p</i> &lt; 0.05) affected mackerel quality, with strong correlations (<i>r</i> &gt; 0.7) between temperature and fat oxidation indicators such as POV. The findings reveal that mackerel samples from summer auctions experienced significant hygiene and quality changes. Notably, 200-g and 300-g mackerel samples showed different patterns of change. This study underscores the unique importance of season and sample weight in assessing seafood quality under climate change, providing a foundation for better distribution and supply of high-quality fresh mackerel amidst rapid climate changes.</p>","PeriodicalId":73042,"journal":{"name":"Food frontiers","volume":"6 3","pages":"1575-1587"},"PeriodicalIF":7.4,"publicationDate":"2025-04-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/fft2.70025","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144140406","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Micronutrient Density of the Global Food Supply","authors":"Nick W. Smith,&nbsp;Ty Beal","doi":"10.1002/fft2.70023","DOIUrl":"https://doi.org/10.1002/fft2.70023","url":null,"abstract":"<p>Global diets are inadequate in micronutrients, leading to deficiencies and related diseases. Addressing these micronutrient shortfalls requires increasing the nutrient density of the global food supply. Inferring micronutrient supply based on food balance sheet data is widespread practice in nutrition modelling, whereas designing food-based interventions is usually done using dietary data. Here, we provide an online interactive tool for investigating the micronutrient density of food balance sheet items, to help identify appropriate food supply interventions to increase the availability of micronutrient-dense foods globally. While the tool can be used for up to 28 food components (including macronutrients), we demonstrate its use by ranking food balance sheet items based on their combined content of 17 micronutrients per 100 g or per 100 kcal. High ranking foods varied between the mass and energy lists, but included offals, seeds, nuts, seafood, and non-starchy vegetables. The tool can be used by nutrition researchers to identify foods with the potential for supplying the specific combinations of micronutrients needed by at-risk populations.</p>","PeriodicalId":73042,"journal":{"name":"Food frontiers","volume":"6 3","pages":"1588-1592"},"PeriodicalIF":7.4,"publicationDate":"2025-04-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/fft2.70023","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144140405","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Highly Targeted Metabolomics Coupled With Gene Expression Analysis by RT–qPCR Improves Beef Separation Based on Grass, Grain, or Grape Supplemented Diet","authors":"Lucas Krusinski,&nbsp;Chloe Castanon,&nbsp;Rosalee S. Hellberg,&nbsp;Isabella C. F. Maciel,&nbsp;Muhammad Ahsin,&nbsp;Stephan van Vliet,&nbsp;Jason E. Rowntree,&nbsp;Jenifer I. Fenton","doi":"10.1002/fft2.70022","DOIUrl":"https://doi.org/10.1002/fft2.70022","url":null,"abstract":"<p>The objective of this study was to use a multi-omics (i.e., gene expression quantification, metabolomics, and fatty acid [FA] profiling) approach to separate and authenticate beef from three different dietary groups. In this 2-year study, Red Angus steers (<i>n</i> = 54) were randomly allocated to one of three treatments: (1) complex biodiverse pasture (GRASS), (2) total mixed ration (TMR) in feedlot (GRAIN), or (3) TMR in feedlot supplemented with 5% (dry matter) grapeseed extract for the last 30 days (GRAPE). FAs were measured by gas chromatography-mass spectrometry (GC–MS), secondary metabolites were identified using ultra-high-performance liquid chromatography tandem mass spectrometry (UPLC–MS/MS), and gene expression analysis was performed using quantitative reverse transcription polymerase chain reaction (RT–qPCR). All target genes were upregulated in beef from GRASS compared to the other two groups. Multivariate analyses showed that long-chain <i>n</i>-3 polyunsaturated FAs, the <i>n</i>-6:<i>n</i>-3 ratio, vitamin E, organic acids, amino acid derivatives, and the nephronectin isoform X1 (<i>NPNT-1</i>) gene were the most important compounds for group separation. These compounds, considered to be beneficial for human health, showed higher concentrations in beef from GRASS. The success of beef separation by dietary treatment was highlighted by the 90.4% prediction accuracy of the random forest model, with beef from GRASS being 100% accurately predicted and beef from GRAPE being 94.4% accurately predicted. Beef from GRAIN was 76.5% accurately predicted. In conclusion, coupling gene expression analysis to metabolomics and FA profiling allowed for the separation of beef samples from varying dietary backgrounds with a high degree of confidence.</p>","PeriodicalId":73042,"journal":{"name":"Food frontiers","volume":"6 3","pages":"1483-1497"},"PeriodicalIF":7.4,"publicationDate":"2025-04-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/fft2.70022","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144140698","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Harnessing Jasminum Bioactive Compounds: Updated Insights for Therapeutic and Food Preservation Innovations","authors":"Antonio Rescigno,&nbsp;Paolo Zucca,&nbsp;Stefania Peddio,&nbsp;Sriranjani Srikanth,&nbsp;Niharika Prakash Kaushik,&nbsp;Nanjangud Venkatesh Anil Kumar,&nbsp;Gerardo Leyva-Gómez,&nbsp;Dorota Kregiel,&nbsp;Ibrahim M. Abu-Reidah,&nbsp;Surjit Sen,&nbsp;Krishnendu Acharya,&nbsp;William N. Setzer,&nbsp;Marta Palma-Morales,&nbsp;Miquel Martorell,&nbsp;Daniela Calina,&nbsp;Celia Rodríguez-Pérez,&nbsp;Javad Sharifi-Rad,&nbsp;William C. Cho","doi":"10.1002/fft2.70024","DOIUrl":"https://doi.org/10.1002/fft2.70024","url":null,"abstract":"<p>The <i>Jasminum</i> genus, renowned for its aromatic flowers, has been used in traditional medicine across various cultures for its therapeutic properties. Recently, scientific interest has focused on the bioactive compounds present in <i>Jasminum</i> species, highlighting their potential applications in health and food preservation. This review evaluates the phytochemical composition of <i>Jasminum</i> species, emphasizing their therapeutic and preservative roles while identifying research gaps. A comprehensive literature search was conducted using major scientific databases, including PubMed, Scopus, and Web of Science, focusing on studies from the last two decades. The review includes peer-reviewed articles that provide robust methodologies and detailed results regarding the biological activities of <i>Jasminum</i> species. Findings reveal that <i>Jasminum</i> is rich in bioactive compounds such as terpenoids, flavonoids, and phenolic acids, contributing to significant antioxidant, anti-inflammatory, antimicrobial, and anticancer properties. Scientific evidence supports traditional uses, such as treating headaches and infections. Additionally, <i>Jasminum</i> extracts have shown promise as natural food preservatives due to their potent antimicrobial activity. However, the review identifies significant variability in study methodologies and a lack of clinical trials, which limit the generalizability and application of these findings. <i>Jasminum</i> species possess a diverse phytochemical profile that holds promise for advancing health and food preservation applications. Future research should prioritize standardizing methodologies and conducting clinical trials to validate their efficacy. Bridging the gap between traditional knowledge and modern science will unlock the full potential of <i>Jasminum</i> as a multifaceted resource for health and nutrition.</p>","PeriodicalId":73042,"journal":{"name":"Food frontiers","volume":"6 3","pages":"1093-1128"},"PeriodicalIF":7.4,"publicationDate":"2025-04-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/fft2.70024","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144140670","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Breast Milk Metabolomic Profile Is Associated With Maternal Overweight/Obesity Status or Adherence to Mediterranean Diet and Infant Weight Gain During the First Month of Lactation","authors":"Catalina A. Pomar,&nbsp;Petr Zouhar,&nbsp;María DeLucas,&nbsp;Tomas Cajka,&nbsp;Pilar Cobo,&nbsp;María Victoria Jiménez-Cabanillas,&nbsp;Pere Bibiloni,&nbsp;Jan Kopecky,&nbsp;Andreu Palou,&nbsp;Francisca Serra,&nbsp;Juana Sánchez,&nbsp;Catalina Picó","doi":"10.1002/fft2.70017","DOIUrl":"https://doi.org/10.1002/fft2.70017","url":null,"abstract":"<p>Breast milk provides a wide range of nutritional and bioactive components crucial for infant growth and development during lactation, ultimately influencing future health outcomes. Here, we used untargeted metabolomics to identify differences in the breast milk metabolome related to maternal overweight/obesity and diet, assessing their influence on infant weight gain in the first month of lactation. Anthropometric data from 52 lactating mother–infant pairs were collected at birth and 1 month postpartum, along with breast milk samples. Information about food consumed the day before milk sampling (24-h questionnaire) was collected, and a food frequency questionnaire was completed. Our findings reveal that mothers with overweight/obesity had greater lactose levels (<i>p</i> = 0.025) and lower levels of orotic acid (<i>p</i> = 0.002), 3-indoxyl sulfate (<i>p</i> = 0.027), heneicosanoic acid (<i>p</i> = 0.040), and N1-methylguanosine (<i>p</i> = 0.046) in milk than normal-weight mothers. Notably, reduced orotic acid levels were associated with a greater infant weight gain during this period. Furthermore, mothers with a low adherence to the Mediterranean diet showed lower levels of citric acid (<i>p</i> = 0.041), N6-succinyladenosine (<i>p</i> = 0.043), uric acid (<i>p</i> = 0.034), and eicosenoic acid (<i>p</i> = 0.035), and higher levels of acylcarnitine C6:0 (<i>p</i> = 0.041) than mothers with a medium/high adherence. Besides orotic acid, other milk metabolites were related to infant weight gain during this period, with maternal fruit and fish consumption (<i>p</i> = 0.015 and <i>p</i> = 0.017) emerging as the most influential dietary factor for an adequate early infant growth trajectory. None of the metabolites identified remained statistically significant after multiple-comparisons adjustment. Present results, showing how maternal diet and obesity can affect breast milk metabolites and infant growth, offer insights to improve lactation-feeding practices and support healthy infant development.</p>","PeriodicalId":73042,"journal":{"name":"Food frontiers","volume":"6 3","pages":"1454-1468"},"PeriodicalIF":7.4,"publicationDate":"2025-04-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/fft2.70017","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144140697","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Anthocyanin Extracts From 11 Superfruits Mitigate Oxidative Stress and Inflammatory Damage in HK-2 Cells Induced by Cadmium Exposure","authors":"Jiaojiao Liang,&nbsp;Yunyi Chen,&nbsp;Manxi Wu,&nbsp;Jiebiao Chen,&nbsp;Cui Sun,&nbsp;Jinping Cao,&nbsp;Yue Wang,&nbsp;Chongde Sun","doi":"10.1002/fft2.70019","DOIUrl":"https://doi.org/10.1002/fft2.70019","url":null,"abstract":"<p>Cadmium (Cd) pollution has emerged as an escalating threat to human health, with its induced kidney toxicity being closely linked to oxidative stress and inflammation. In this study, we extracted and analyzed primary anthocyanins from 11 superfruits using UPLC-Triple-TOF/MS and evaluated their antioxidant capacity through DPPH, ABTS, FRAP, and ORAC assays. By employing a Cd-exposed Human Kidney-2 (HK-2) cells injury model, we investigated the protective effects of superfruit anthocyanin extracts. The results demonstrated that these extracts enhanced HK-2 cell viability, increased T-SOD and GSH levels, and reduced ROS, MDA, and NO. Furthermore, they significantly regulated oxidative stress and inflammation-related genes and proteins. Moreover, we elucidated the mechanisms by which these anthocyanins mitigate Cd-induced cellular damage via classical oxidative and inflammatory pathways. These findings highlight the potential of specific anthocyanin-rich fruits in reducing Cd-related health risks and suggest practical applications for their bioactive properties in promoting human health.</p>","PeriodicalId":73042,"journal":{"name":"Food frontiers","volume":"6 3","pages":"1558-1574"},"PeriodicalIF":7.4,"publicationDate":"2025-04-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/fft2.70019","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144140681","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Exploring Proteomic and Metabolomic Interactions in a Yeast Consortium Designed to Enhance Bioactive Compounds in Wine Fermentations","authors":"Andrés Planells-Cárcel,&nbsp;Guillermo Quintas,&nbsp;Judit Pardo,&nbsp;Estefani Garcia-Rios,&nbsp;José Manuel Guillamón","doi":"10.1002/fft2.70018","DOIUrl":"https://doi.org/10.1002/fft2.70018","url":null,"abstract":"<p>There is a new trend in modern oenology to inoculate more than one yeast strain in order to increase microbial diversity and respond to some of the new demands of the wine market. The presence of bioactive molecules in wine is clearly one of these consumer demands, as it can contribute to the bioactivity, quality, and stability of the final products. As many of these bioactive molecules are a consequence of yeast metabolism, our aim in this study was to increase the concentration of tryptophan-derived indole metabolites using a consortium of two <i>Saccharomyces</i> strains, one <i>Saccharomyces cerevisiae</i> (<i>Sc</i>) and one <i>Saccharomyces uvarum (Su)</i>, and to understand the molecular and metabolic mechanisms that led to the enhanced biosynthesis of these molecules. The comparison of the proteome of these two strains growing in pure and co-inoculated fermentation, together with a metabolic study of the final wines, has revealed the main strategies of competence in both species. Both proteomic and metabolomic data indicated that the presence of a competitive strain in the same fermentation medium accelerated the growth rate of <i>Sc</i>, upregulated protein translation and ribosome formation, whereas it enhanced the production of bioactive molecules derived from tryptophan in <i>Su</i>, which showed a natural enrichment in metabolites of aromatic amino acid biosynthesis pathway. This study confirmed the idea of combining yeast strains and species as an oenological tool to produce wines of different quality and the need to study the mechanisms of interaction between strains in order to predict the final results.</p>","PeriodicalId":73042,"journal":{"name":"Food frontiers","volume":"6 3","pages":"1544-1557"},"PeriodicalIF":7.4,"publicationDate":"2025-04-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/fft2.70018","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144140268","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Microalgae: A Solution for Food Security and Multiplanetary Farming","authors":"Xiulan Xie,&nbsp;Jiasui Zhan,&nbsp;Maozhi Ren","doi":"10.1002/fft2.70020","DOIUrl":"https://doi.org/10.1002/fft2.70020","url":null,"abstract":"<p>Human civilization is threatened by food insecurity and habitat loss owing to the cumulative effects of anthropogenic and natural factors. Thus, increasing food production while using fewer resources and exploring the potential of interstellar migration is essential. Particularly, microalgae can fulfil the biological, nutritional, and efficiency requirements of industrial food production on Earth and other potential planets. Herein, we discuss the industrial production of microalgae on Earth and in outer space, along with the technological advances that will help reshape the genetic and chemical properties of microalgae for better production, nutrition, and adaptation. We propose the concept of “multiplanetary farming” to address future requirements for agricultural development. This perspective review is intended to stimulate a broad debate and research on this paramount issue for the future of mankind.</p>","PeriodicalId":73042,"journal":{"name":"Food frontiers","volume":"6 3","pages":"1242-1251"},"PeriodicalIF":7.4,"publicationDate":"2025-04-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/fft2.70020","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144140264","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Broccoli and Arthritis: A Review","authors":"Mingyuan Song,&nbsp;Xingquan Xu,&nbsp;Prachi Wele,&nbsp;Ding Wei,&nbsp;Xian Wu,&nbsp;Wenjin Yan","doi":"10.1002/fft2.70015","DOIUrl":"https://doi.org/10.1002/fft2.70015","url":null,"abstract":"<p>Arthritis is a disease characterized by joint pain, swelling, and limited mobility and is also a major cause of disability. Osteoarthritis (OA) and rheumatoid arthritis (RA) are the two most common manifestations of arthritis, and they share many common risk factors and pathogenic features. At present, there is no effective approach to prevent the disease or slow its progress. Nonetheless, many treatments can alleviate symptoms and improve the quality of life of patients. Among, antioxidant supplement therapy has become one of the most popular methods as it can inhibit the formation of reactive oxygen species (ROS) in chondrocytes, which is a key step in the pathogenesis of arthritis. Broccoli is rich in many essential nutrients, including fibers, vitamins, minerals, and various bioactive components. Thus, a dietary supplement of broccoli holds potential as a preventive measure against arthritis due to its widespread popularity, safety profile, and affordability. However, no review of the clinical and pre-clinical studies of broccoli on arthritis is available so far. Therefore, this systematic review aims to critically evaluate the efficacy and safety of broccoli and its bioactive constituents in the treatment of arthritis. Although the current evidence falls short of establishing a definitive effect of broccoli on arthritis due to a limited number of clinical studies and significant heterogeneity among the existing research, current research provides overall support for the potential benefits of broccoli and its bioactive components in preventing and managing arthritis and the use of broccoli as an adjuvant treatment for individuals with arthritis.</p>","PeriodicalId":73042,"journal":{"name":"Food frontiers","volume":"6 3","pages":"1252-1270"},"PeriodicalIF":7.4,"publicationDate":"2025-04-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/fft2.70015","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144140266","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}