Food frontiers最新文献

{"title":"Cover Image: Volume 6, Issue 2","authors":"","doi":"10.1002/fft2.70016","DOIUrl":"https://doi.org/10.1002/fft2.70016","url":null,"abstract":"<p>The cover image is based on the Review Article <i>Structural insights and biological activities of flavonoids: Implications for novel applications</i> by Sheng Tang et al., https://doi.org/10.1002/fft2.494.\u0000\u0000 <figure>\u0000 <div><picture>\u0000 <source></source></picture><p></p>\u0000 </div>\u0000 </figure></p>","PeriodicalId":73042,"journal":{"name":"Food frontiers","volume":"6 2","pages":""},"PeriodicalIF":7.4,"publicationDate":"2025-03-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/fft2.70016","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143689268","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Food for Thought: How Culture Shapes Intentions to Reduce Food Waste in South Africa","authors":"Wibke Heidig,&nbsp;Thomas Dobbelstein,&nbsp;Roger B. Mason","doi":"10.1002/fft2.544","DOIUrl":"https://doi.org/10.1002/fft2.544","url":null,"abstract":"<p>In the context of increasing food scarcity, the issue of household food waste has garnered significant attention, particularly in developing nations. Despite its critical importance, there remains a paucity of empirical research exploring the underlying behavioral and cultural factors that shape individuals’ intentions to reduce food waste within their homes. This article seeks to bridge this gap by drawing on the theory of planned behavior to examine how personal cultural values impact attitudes toward food waste reduction, subjective norms, and perceived behavioral control (PBC), which serve as key determinants of behavioral intention. To empirically test the proposed model, a comprehensive quantitative survey was conducted among 529 South African consumers. The data were analyzed using structural equation modeling, revealing that consumers who exhibit stronger adherence to cultural dimensions such as uncertainty avoidance and long-term orientation, coupled with lower scores on power distance, are likely, through the influence of attitude, subjective norms, and PBC, to possess higher intentions to actively reduce food waste. These findings offer valuable insights for marketers and policymakers, highlighting the potential to leverage cultural values in designing effective interventions aimed at encouraging more sustainable consumer behaviors and reducing household food waste.</p>","PeriodicalId":73042,"journal":{"name":"Food frontiers","volume":"6 2","pages":"956-978"},"PeriodicalIF":7.4,"publicationDate":"2025-02-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/fft2.544","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143689264","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Amination of Flavonoids Possessing a Pyrogallol Group in Cell Culture Medium at 37°C","authors":"Haolin Zhang,&nbsp;Jingjing Zhang,&nbsp;Hui Cao,&nbsp;Petra Högger,&nbsp;Randolph Arroo,&nbsp;Mohamed A. Farag,&nbsp;Avi Shpigelman,&nbsp;Jianbo Xiao,&nbsp;Chunlin Li","doi":"10.1002/fft2.70002","DOIUrl":"https://doi.org/10.1002/fft2.70002","url":null,"abstract":"<p>A class of flavonoid aminated derivatives that had been consistently overlooked in literature was shown to be formed as artefacts in cell culture medium. In this study, 34 flavonoids from different subclasses were incubated in Dulbecco's modified Eagle's Medium (DMEM) at 37°C for 2 h to identify the reaction mechanism behind aminated derivatives formation from flavonoids. Baicalein, scutellarein, dihydromyricetin, (−)-gallocatechin (GC), (−)-epigallocatechin (EGC), (−)-GC gallate, and (−)-EGC gallate were found to yield corresponding nitrogenous derivatives in both DMEM and amino acid solution. The nitrogen source of these seven flavonoid -aminated derivatives was revealed to be amino acids in DMEM. The pyrogallol group of the flavonoids was a key structural motif, being first oxidized into quinone and then further reacting with amino acids (Strecker degradation) to yield aminated flavonoids and corresponding aldehydes. A slightly alkaline environment accelerated the amination of flavonoids, possibly via the formation of flavonoid quinone. These results provide the mechanistic evidence for the in vitro generation of flavonoid -aminated derivatives, yet to be tested using in vivo assays.</p>","PeriodicalId":73042,"journal":{"name":"Food frontiers","volume":"6 2","pages":"1058-1078"},"PeriodicalIF":7.4,"publicationDate":"2025-02-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/fft2.70002","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143689045","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Recent Advances in Detection and Control Strategies for Foodborne Bacteria in Raw and Ready-to-Eat Fruits and Vegetables","authors":"Asem M. Abdelshafy,&nbsp;Hala A. Younis,&nbsp;Ahmed I. Osman,&nbsp;Saleh M. Hussein,&nbsp;Amr S. Abou El-Ela,&nbsp;Elsayed A. Mahmoud,&nbsp;Osama Elsherbiny,&nbsp;Ahmed K. Rashwan","doi":"10.1002/fft2.541","DOIUrl":"https://doi.org/10.1002/fft2.541","url":null,"abstract":"<p>The prevalence of foodborne outbreaks due to the consumption of uncooked and ready-to-eat fruits and vegetables has seen a noticeable increase, particularly in environments lacking sanitation. This article extensively explores recent advancements in the detection of foodborne pathogens in uncooked and ready-to-eat fruits and vegetables, alongside potential prevention strategies. Predominantly, pathogens like <i>Listeria monocytogenes</i>, <i>Escherichia coli</i>, and <i>Salmonella enterica</i> are the main culprits in outbreaks linked to these food items globally. Notably, contamination is more prevalent in fresh leafy greens than in fruit products. Various detection methods such as culturing, microscopy, immunological assays, polymerase chain reaction (PCR), biosensors, and hyperspectral imaging have proven effective in identifying pathogens in these foods. Nonetheless, these methods come with challenges, including time consumption, accuracy concerns, and high costs. Research is ongoing to refine these detection techniques, with efforts including combining methodologies like PCR–enzyme-linked immunosorbent assay and integrating culturing with PCR. Additionally, several interventions, including cold plasma treatment, ultraviolet irradiation, and the application of edible coatings, have shown promise in mitigating contamination risks, thereby enhancing the safety of these fresh produce items.</p>","PeriodicalId":73042,"journal":{"name":"Food frontiers","volume":"6 2","pages":"605-629"},"PeriodicalIF":7.4,"publicationDate":"2025-01-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/fft2.541","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143689836","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Dynamic Evolution of Mung Bean Protein in Alkaline Solutions: Unravelling Vicilin Function Through Molecular Simulation","authors":"Afsaneh Taheri,&nbsp;Fatin Natasha Binte Abdul Halim,&nbsp;Juan Du","doi":"10.1002/fft2.520","DOIUrl":"https://doi.org/10.1002/fft2.520","url":null,"abstract":"<p>This study explored the effects of pH-shifting over 0, 10, 20, and 30 min on the physicochemical characteristics of mung bean protein (MBP) isolates, identified as MBP₀, MBP₁₀, MBP₂₀, and MBP₃₀. The conformational features of vicilin-type (8S), the primary component of MBP, were studied using molecular dynamics simulations. Our findings revealed the time-dependent nature of pH-shifting on protein flexibility, which caused changes in surface charges of MBP from 0 to 30 min. An increase in particle size, solubility, and more uniform distribution among all pH-shifted samples were observed due to swelling. Smoother and flakier structures in pH-shifted proteins were detected by scanning electron microscope. Molecular simulations at pH 12.0 revealed enhanced stability of vicilin with greater fluctuation of hydrophilic residues and increased flexibility, which correlated to the experimental results, highlighting vicilin's pivotal role in the flexibility and solubility of MBP during pH changes.</p>","PeriodicalId":73042,"journal":{"name":"Food frontiers","volume":"6 2","pages":"909-920"},"PeriodicalIF":7.4,"publicationDate":"2025-01-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/fft2.520","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143689151","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Amauroderma rugosum Extract Improves Brain Function in d-Galactose-Induced Aging Mouse Models via the Regulatory Effects of Its Polysaccharides on Oxidation, the mTOR-Dependent Pathway, and Gut Microbiota","authors":"Panthakarn Rangsinth,&nbsp;Chengwen Zheng,&nbsp;Polly Ho-Ting Shiu,&nbsp;Wen Wang,&nbsp;Tsz Ching Kwong,&nbsp;Chi Tung Choy,&nbsp;Susan Wai-Sum Leung,&nbsp;Tewin Tencomnao,&nbsp;Siriporn Chuchawankul,&nbsp;Anchalee Prasansuklab,&nbsp;Timothy Man-Yau Cheung,&nbsp;Yiu-Wa Kwan,&nbsp;Priya Kannan,&nbsp;Jingjing Li,&nbsp;George Pak-Heng Leung","doi":"10.1002/fft2.543","DOIUrl":"https://doi.org/10.1002/fft2.543","url":null,"abstract":"<p>The pharmacological effects of <i>Amauroderma rugosum</i> (AR), an edible mushroom found mainly in Southeast Asia, are not well studied, particularly its neuroprotective properties. This study investigated the neuroprotective effects of AR aqueous extract (ARW) in a <span>d</span>-galactose-induced accelerated aging mouse model and senescent SH-SY5Y neuronal cells. Behavioral tests (open field, Morris water maze, Y-maze, and rotarod) demonstrated that <span>d</span>-galactose-induced aging mice exhibited impaired cognitive function, memory loss, anxiety, and reduced locomotor ability, all of which were alleviated by ARW treatment. Histological analysis showed that ARW reduced neuropathological lesions in the hippocampus. In SH-SY5Y neuronal cells, ARW and AR polysaccharide extract (ARP) enhanced cell viability and decreased intracellular reactive oxygen species (ROS) levels in a concentration-dependent manner. ARW and ARP also reduced cellular senescence and apoptosis in <span>d</span>-galactose-treated cells. Western blot analysis indicated that ARW and ARP upregulated the phosphorylation of mTOR and increased the expression of antioxidant enzymes, including superoxide dismutase 1 and heme-oxygenase-1. Additionally, ARW altered the gut microbiota, increasing the relative abundance of beneficial bacteria such as <i>Lactobacillus reuteri</i> and decreasing harmful bacteria like <i>Clostridium scindens</i>. These findings suggest that AR exerts neuroprotective effects primarily through its polysaccharides by modulating oxidative stress, activating the mTOR-dependent pathway, and influencing the gut microbiota. Consequently, AR could serve as a potential dietary supplement for the prevention and treatment of neurodegenerative diseases.</p>","PeriodicalId":73042,"journal":{"name":"Food frontiers","volume":"6 2","pages":"872-890"},"PeriodicalIF":7.4,"publicationDate":"2025-01-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/fft2.543","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143689032","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Correction to “The Algal Polysaccharide Ulvan Suppresses Growth of Hepatoma Cells”","authors":"","doi":"10.1002/fft2.540","DOIUrl":"https://doi.org/10.1002/fft2.540","url":null,"abstract":"<p>Zhao, C., G. Lin, D. Wu, et al. 2020. “The Algal Polysaccharide Ulvan Suppresses Growth of Hepatoma Cells.” <i>Food Frontiers</i> 1: 83–101. https://doi.org/10.1002/fft2.13.</p><p>In the version of this article initially published, there was an error in Figure 10. The p65 in Figure 10(b) is identical to TRAF2. The other elements of the figure remain the same, and the interpretation of the results remains unchanged. The corrected Figure 10 is reproduced below.</p>","PeriodicalId":73042,"journal":{"name":"Food frontiers","volume":"6 1","pages":"599-600"},"PeriodicalIF":7.4,"publicationDate":"2024-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/fft2.540","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143121328","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Preparation of Collagen Peptide Nanoliposomes From Sturgeon Fish Cartilage and Explore Their Anti-Osteoarthritis Effects in Rats","authors":"Chia-Chi Kung,&nbsp;Mei-Zhen Lin,&nbsp;Bing-Huei Chen","doi":"10.1002/fft2.539","DOIUrl":"https://doi.org/10.1002/fft2.539","url":null,"abstract":"<p>This study aims to extract pepsin soluble collagen (PSC) from sturgeon cartilage, hydrolyze to sturgeon cartilage collagen peptides (SCCP), and prepare SCCP nanoliposomes to explore the treatment effects of osteoarthritis (OA) in rats. PSC was extracted using 0.5 M acetic acid and pepsin (10%) and enzymatically hydrolyzed with 4.5% alcalase plus 4.5% flavourzyme to obtain SCCP. Amino acid analysis revealed the presence of glycine, proline, and hydroxyproline in high amounts, while SDS-PAGE showed that the PSC belonged to type II collagen with molecular weight (MW) of SCCP being &lt;2 kDa and MALDI-TOF-MS indicated the MW distribution to range from 302.594 to 683.050 Da with the peptide fragments &lt;500 Da accounting for 89.71%. SCCP nanoliposomes composed of phosphatidylcholine, fatty acid sucrose ester, glycerol, and deionized water were prepared with size at 34.58 nm, polydispersity index at 0.19, zeta potential at -54.53 mV, and encapsulation efficiency at 88.14%. Tube feeding of SCCP/SCCP nanoliposomes into OA rats alleviated pain responses by joint damage through reduction in hind limb weight-bearing difference, knee joint width difference, and levels of serum biomarkers including CTX-II, TGF-β1, PIICP, and COMP. Histopathologic images demonstrated the mitigation of joint damage symptoms in the tissue by reducing cartilage joint damage, inhibiting chondrocyte apoptosis, promoting chondrocyte regeneration, and reducing synovitis. Collectively, the high dose of SCCP nanoliposomes was the most effective in alleviating OA possessing a great potential to be developed into a health food or botanic drug for the treatment of joint-related disease.</p>","PeriodicalId":73042,"journal":{"name":"Food frontiers","volume":"6 2","pages":"727-749"},"PeriodicalIF":7.4,"publicationDate":"2024-12-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/fft2.539","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143689606","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Valorizing Agro-Food Waste for Nutraceutical Development: Sustainable Approaches for Managing Metabolic Dysfunction-Associated Steatotic Liver Disease and Related Co-Morbidities","authors":"Laura Comi,&nbsp;Claudia Giglione,&nbsp;Fationa Tolaj Klinaku,&nbsp;Federico Pialorsi,&nbsp;Valentina Tollemeto,&nbsp;Maria Zurlo,&nbsp;Antonio Seneci,&nbsp;Paolo Magni","doi":"10.1002/fft2.535","DOIUrl":"https://doi.org/10.1002/fft2.535","url":null,"abstract":"<p>This comprehensive investigation delves into the interconnectedness of different features of cardiometabolic syndrome, such as metabolic dysfunction-associated steatotic liver disease (MASLD), atherosclerotic cardiovascular disease (ASCVD), and gut dysbiosis, highlighting the crucial role of nutraceuticals in their management and prevention. Given the significant overlap in the pathophysiology of these conditions, the treatment with nutraceuticals, especially those derived from agro-food waste, offers a promising, sustainable, and innovative approach to healthcare. The 2030 Agenda for Sustainable Development and the One Health concept are key frameworks for selecting the most interesting supply chain for the production of nutraceuticals from agro-food waste, ensuring environmental sustainability, and innovative agricultural practices. In this review, the therapeutic potential of kiwifruit and apples has been explored, detailing how their bioactive compounds, like polyphenols, fiber, pectin, kaempferol, phloretin, and phlorizin, may contribute to the management of MASLD, ASCVD, and gut dysbiosis. Various extraction methods for active ingredients, including chemical, water, and enzyme extractions, are analyzed for their respective benefits and drawbacks. By integrating scientific research, sustainable agricultural practices, and innovative extraction methods, we can develop effective strategies to combat these pervasive health issues. This holistic approach not only enhances individual health outcomes but also supports broader environmental and societal goals, promoting a healthier future for all.</p>","PeriodicalId":73042,"journal":{"name":"Food frontiers","volume":"6 2","pages":"670-697"},"PeriodicalIF":7.4,"publicationDate":"2024-12-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/fft2.535","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143689605","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Identification of the Heptapeptide PR7 and Octapeptide SF8 With Potent Antioxidative and Angiotensin Converting Enzyme Inhibitory Activity From the Fermented Dairy By-Product “Buttermilk”","authors":"Osama Magouz,&nbsp;Mahmoud A. A. Ibrahim,&nbsp;Nabil Mehanna,&nbsp;Sabrina Gensberger-Reigl,&nbsp;Sevim Dalabasmaz,&nbsp;Monika Pischetsrieder","doi":"10.1002/fft2.538","DOIUrl":"https://doi.org/10.1002/fft2.538","url":null,"abstract":"<p>The present study aimed to identify antioxidative and angiotensin converting enzyme (ACE) inhibitory peptides in fermented buttermilk after simulated gastric digestion. Following isoelectric focusing fractionation, peptides of the most active fractions were identified by ultrahigh performance liquid chromatography–tandem mass spectrometry (UHPLC–MS/MS). Subsequently, 23 peptides were synthesized and tested for antioxidative and ACE inhibitory activity. The peptide PR7 (PWDQVKR, αs2-casein 108–114) exerted comparable antioxidative activity to ascorbic acid, whereas the peptide SF8 (SGPLRPFF, butyrophilin 427–434) efficiently inhibited ACE with an IC₅₀ value of 1.57 µM. The binding modes of the five most active ACE inhibitors were predicted using AlphaFold2 multimer software. Molecular mechanics (MM) minimization and molecular dynamics (MD) simulations of all complexes, followed by MM-generalized born surface area (GBSA) binding energy calculations, were predicted. Notably, these peptides manifested good binding affinities to ACE. The estimated MM-GBSA/MD binding energies correlated with the detected IC₅₀ values [correlation coefficient (<i>R</i>²) = 0.79]. Post-MD analyses over 100 ns elucidated the steadiness of the five peptides.</p>","PeriodicalId":73042,"journal":{"name":"Food frontiers","volume":"6 2","pages":"837-851"},"PeriodicalIF":7.4,"publicationDate":"2024-12-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/fft2.538","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143688947","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}