Bulletin De L Academie Nationale De Medecine最新文献

Homo Addictus : approche anthropologique des addictions Homo Addictus：成瘾的人类学方法

IF 0.3 4区医学

Bulletin De L Academie Nationale De Medecine Pub Date : 2026-07-01 Epub Date: 2026-07-07 DOI: 10.1016/j.banm.2026.05.022

Driss Moussaoui

引用次数: 0

Situation de l’usage de drogues psychoactives au Brésil 巴西使用精神药物的情况

IF 0.3 4区医学

Bulletin De L Academie Nationale De Medecine Pub Date : 2026-07-01 Epub Date: 2026-07-09 DOI: 10.1016/j.banm.2026.05.025

Bernardo Madeira Diefenthaeler, Santiago Madeira Diefenthaeler, Antonio Egidio Nardi, Flavio Kapczinski

{"title":"Situation de l’usage de drogues psychoactives au Brésil","authors":"Bernardo Madeira Diefenthaeler, Santiago Madeira Diefenthaeler, Antonio Egidio Nardi, Flavio Kapczinski","doi":"10.1016/j.banm.2026.05.025","DOIUrl":"10.1016/j.banm.2026.05.025","url":null,"abstract":"<div><div>The consumption of psychoactive drugs constitutes a significant public health problem in Brazil. This article aimed to synthesize and discuss the panorama of the use of licit and illicit substances in the country, highlighting epidemiological patterns, health consequences, and gaps in scientific knowledge. This is a narrative review based on secondary data, with the main source being the Third National Survey on Drug Use by the Brazilian Population, complemented by the existing national and international literature on the subject. The data indicate that alcohol is the most commonly consumed substance (43.1% in the past 12 months), with a prevalence similar to the global average. Cigarette consumption stands out for having shown a marked reduction over the past decades, with a current prevalence of 17.3% in the past 12 months. Among illicit drugs, cannabis was the most used (2.5% in the past year), followed by cocaine (0.9%) and crack (0.3%). Overall, men showed higher prevalence of use, except for non-prescribed medications. Despite advances in tobacco control policies, challenges remain related to alcohol, cocaine, and crack, as well as to the emergence of new substances and limited access to treatment. The periodic updating of national surveys and the expansion of harm reduction strategies are essential to improve public health responses.</div></div>","PeriodicalId":55317,"journal":{"name":"Bulletin De L Academie Nationale De Medecine","volume":"210 6","pages":"Pages S33-S41"},"PeriodicalIF":0.3,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148576006","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Drogues et substances illicites : dynamiques européennes 毒品和非法物质：欧洲的动态

IF 0.3 4区医学

Bulletin De L Academie Nationale De Medecine Pub Date : 2026-07-01 Epub Date: 2026-07-09 DOI: 10.1016/j.banm.2026.05.026

Francis Megerlin

引用次数: 0

La fin du tabac ? 烟草的终结？

IF 0.3 4区医学

Bulletin De L Academie Nationale De Medecine Pub Date : 2026-07-01 Epub Date: 2026-07-11 DOI: 10.1016/j.banm.2026.05.020

Gérard Dubois

引用次数: 0

Discussion à propos de la communication : « Épidémiologie de l’infertilité en France et dans le monde » 关于沟通的讨论：“法国和世界的不孕症流行病学”

IF 0.3 4区医学

Bulletin De L Academie Nationale De Medecine Pub Date : 2026-07-01 Epub Date: 2026-05-23 DOI: 10.1016/j.banm.2026.05.014

Jean-Marc Ayoubi

引用次数: 0

Les nouvelles drogues de synthèse et leur moyen de détection 新型合成药物及其检测方法

IF 0.3 4区医学

Bulletin De L Academie Nationale De Medecine Pub Date : 2026-07-01 Epub Date: 2026-07-08 DOI: 10.1016/j.banm.2026.05.017

Jean-Claude Alvarez

{"title":"Les nouvelles drogues de synthèse et leur moyen de détection","authors":"Jean-Claude Alvarez","doi":"10.1016/j.banm.2026.05.017","DOIUrl":"10.1016/j.banm.2026.05.017","url":null,"abstract":"<div><div>New psychoactive substances (NPS) refer to new narcotic or psychotropic substances not controlled by the United Nations drug conventions, which pose a threat to public health due to their toxicity. They comprise a large number of diverse substances, synthetic analogues of existing drugs with a slightly modified chemical formula but which mimic the pharmacological effects of the illicit products from which they are derived. They are widely available and easily sold online. There are numerous pharmacological classes, the most significant being cathinones and their derivatives, synthetic cannabinoids, synthetic opioids (fentanyl derivatives and nitazenes), synthetic benzodiazepines, as well as other classes such as ketamine derivatives. They first appeared in the early 2000s. The number of newly identified NDS each year rose, peaking in 2014 with over a hundred new drugs identified that year. Since then, this number has stabilised at around forty per year. By the end of 2024, 1003 NDS were under surveillance in Europe, including 277 cannabinoids and 178 cathinones. Their identification is difficult because they do not give positive results in standard drug tests. There are few screening methods available, and these substances are not among those tested for during road safety checks. Their definitive identification and quantification rely on chromatography coupled with mass spectrometry, or even high-resolution mass spectrometry when their structures are not yet known and have not been included in spectral libraries.</div></div>","PeriodicalId":55317,"journal":{"name":"Bulletin De L Academie Nationale De Medecine","volume":"210 6","pages":"Pages S97-S103"},"PeriodicalIF":0.3,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148576062","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Syndrome de Turner : une pathologie génétique de la croissance, au-delà d’un déficit en hormone de croissance. Du retard statural au dépistage précoce 特纳综合征：一种生长的遗传病理，除了缺乏生长激素。从延迟到早期发现

IF 0.3 4区医学

Bulletin De L Academie Nationale De Medecine Pub Date : 2026-07-01 Epub Date: 2026-06-26 DOI: 10.1016/j.banm.2026.05.005

Michel Polak, Reem Eid

{"title":"Syndrome de Turner : une pathologie génétique de la croissance, au-delà d’un déficit en hormone de croissance. Du retard statural au dépistage précoce","authors":"Michel Polak, Reem Eid","doi":"10.1016/j.banm.2026.05.005","DOIUrl":"10.1016/j.banm.2026.05.005","url":null,"abstract":"<div><div>Turner syndrome is a chromosomal disorder caused by complete or partial loss of one X chromosome and consistently associated with short stature due to gene dosage effects. Without treatment, mean adult height is approximately 142cm. Recombinant growth hormone therapy provides an average height gain of 5 to 10cm. This review analyzes the determinants of height response and the optimal use of growth hormone therapy. Efficacy mainly depends on the age at initiation, treatment duration, administered dose, karyotype, and optimal moment of pubertal induction. Early initiation, ideally before four to six years of age, is associated with greater final height gain. Recommended dosing ranges from 0.045 to 0.067mg/kg/day. Gradual introduction of low-dose estrogen therapy around 11–12 years of age optimizes residual growth. Despite proven efficacy, substantial interindividual variability remains linked to genetic and therapeutic factors. Diagnosis is still frequently delayed. Recent advances in genetics raise the possibility of earlier detection strategies, which may improve management and long-term height outcomes.</div></div>","PeriodicalId":55317,"journal":{"name":"Bulletin De L Academie Nationale De Medecine","volume":"210 6","pages":"Pages 720-724"},"PeriodicalIF":0.3,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148588959","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Discussion à propos de la communication : « Modèles dérivés de patients pour les maladies chroniques hépatiques et les cancers du foie : vers une médecine de précision » 关于交流的讨论：“慢性肝病和肝癌患者衍生模型：迈向精确医学”

IF 0.3 4区医学

Bulletin De L Academie Nationale De Medecine Pub Date : 2026-07-01 Epub Date: 2026-05-24 DOI: 10.1016/j.banm.2026.05.015

Thomas F. Baumert

引用次数: 0

Abus, mésusages et détournements des psychotropes : évolution récente et perspective 滥用、误用和滥用精神药物：最近的发展和前景

IF 0.3 4区医学

Bulletin De L Academie Nationale De Medecine Pub Date : 2026-07-01 Epub Date: 2026-07-10 DOI: 10.1016/j.banm.2026.05.016

Antoine Coquerel

{"title":"Abus, mésusages et détournements des psychotropes : évolution récente et perspective","authors":"Antoine Coquerel","doi":"10.1016/j.banm.2026.05.016","DOIUrl":"10.1016/j.banm.2026.05.016","url":null,"abstract":"<div><div>Abuse, misuse, and diversion of psychotropic medicines are highly prevalent. They affect multiple populations, including older adults with insomnia or anxiety (benzodiazepines [BZDs] and Z-drugs), patients with chronic pain (gabapentinoids and both weak and strong opioids), and a substantial proportion of individuals with illicit drug dependence, particularly opioid use disorder (buprenorphine, methadone). While some instances of misuse and diversion occur in recreational contexts (e.g., “purple drank,” nitrous oxide), others serve criminal purposes (drug-facilitated crime, prescription trafficking). In response to these growing phenomena — paralleling trends in drug trafficking and use — regulatory actions and legislation can mitigate misuse and diversion. In France, such measures are typically informed by investigations conducted by the Centres for Evaluation and Information on Pharmacodependence–Addictovigilance (CEIP-A) network. Their impact has been particularly notable for BZDs and Z-drugs, as well as for opioid substitution therapies, contributing to the absence of a major opioid crisis in France.</div></div>","PeriodicalId":55317,"journal":{"name":"Bulletin De L Academie Nationale De Medecine","volume":"210 6","pages":"Pages S67-S74"},"PeriodicalIF":0.3,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148576010","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

La variabilité du phénotype somatique en fonction du mosaïcisme chromosomique dans le syndrome de Turner 躯体表型的可变性与特纳综合征的染色体马赛克有关

IF 0.3 4区医学

Bulletin De L Academie Nationale De Medecine Pub Date : 2026-07-01 Epub Date: 2026-05-23 DOI: 10.1016/j.banm.2026.05.009

Jacques Battin

引用次数: 0