Chem Catalysis最新文献_第3页

Unimolecular synergistic precatalysts for visible-light-driven PINO catalysis 可见光驱动的单分子协同预催化剂

IF 9.4

Chem Catalysis Pub Date : 2026-09-10 DOI: 10.1016/j.checat.2026.101863

Dejing Xu,Tianyuan Pan,Ruozhou Huang,Chenjuan Yu,Zhicheng Deng,Yuping Wang

引用次数: 0

Reverse polarization degradation of nickel iron oxyhydroxide anodes in alkaline water electrolysis 碱性电解镍铁氧化阳极的反极化降解

IF 9.4

Chem Catalysis Pub Date : 2026-09-09 DOI: 10.1016/j.checat.2026.101845

Manasa Rajeev,Fernanda Brito dos Santos,Shannon W. Boettcher,Paul A. Kempler

引用次数: 0

Designing molecular catalysts for zinc-iodine batteries 锌碘电池分子催化剂设计

IF 9.4

Chem Catalysis Pub Date : 2026-09-02 DOI: 10.1016/j.checat.2026.101839

Feifei Wang,Chunpeng Yang

引用次数: 0

Copper-catalyzed enantioselective CO2-bridged hydrodimerization of 1,3-enynes to access C2-symmetric alkynylols 铜催化1,3-炔的对映选择性co2桥接加氢二聚反应以获得c2对称炔基醇

IF 9.4

Chem Catalysis Pub Date : 2026-09-02 DOI: 10.1016/j.checat.2026.101843

Yuhan Cao,Wenrui Zheng,Fen Mi,Yi Han,Chunyan Chi,Yixin Lu

引用次数: 0

Electrofuel recipes for decoupled electro-biosystems in zero-carbon biomanufacturing 零碳生物制造中解耦电生物系统的电燃料配方

IF 9.4

Chem Catalysis Pub Date : 2026-09-02 DOI: 10.1016/j.checat.2026.101840

Tingting Zheng,Yuan Ji,Mingming Guo,Xiang Gao,Chuan Xia

引用次数: 0

Bifunctional dual active center design for selective hydrogenation of unsaturated functional groups 不饱和官能团选择性氢化的双功能双活性中心设计

IF 9.4

Chem Catalysis Pub Date : 2026-08-31 DOI: 10.1016/j.checat.2026.101837

Xiaocheng Lan,Chuanyu Si,Dehuai Liu,Shusen Liu,Tiefeng Wang

引用次数: 0

Nickel-catalyzed precision deuteration of pharmaceutical for deuterated drug development 镍催化药物的精确氘化，用于氘化药物的研制

IF 9.4

Chem Catalysis Pub Date : 2026-08-31 DOI: 10.1016/j.checat.2026.101827

Chloé Tatol,Anvi Laëtitia Nguyen,Florence Castelli,Edmond Gravel,Maxime Jay,Sophie Feuillastre,Grégory Pieters

{"title":"Nickel-catalyzed precision deuteration of pharmaceutical for deuterated drug development","authors":"Chloé Tatol,Anvi Laëtitia Nguyen,Florence Castelli,Edmond Gravel,Maxime Jay,Sophie Feuillastre,Grégory Pieters","doi":"10.1016/j.checat.2026.101827","DOIUrl":"https://doi.org/10.1016/j.checat.2026.101827","url":null,"abstract":"Facilitating the access to therapeutic agents with optimized pharmacological properties remains a priority to improve human health. For azine-based active pharmaceutical ingredients, deuteration at their metabolic soft spot showed promise in improving the safety and pharmacokinetic profile of related drug candidates. In this context, the development of straightforward and efficient methods enabling the precise deuteration at these specific positions is essential to foster drug discovery and development. Herein, we describe an easy-to-implement method achieving high isotopic enrichments and regioselectivities for the precise deuteration of various azines, including pharmaceuticals. This hydrogen isotope exchange reaction relied on the in situ generation of nickel nanoparticles using deuterium gas as the isotopic source. While the broad substrate scope, excellent functional group tolerance, and ease of implementation of this method demonstrate its potential to accelerate the development of deuterated drugs, we further established that precise deuterium incorporation can serve as a strategic tool in prodrug design.","PeriodicalId":53121,"journal":{"name":"Chem Catalysis","volume":"268 1","pages":""},"PeriodicalIF":9.4,"publicationDate":"2026-08-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148877425","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Thermostable artificial nicotinamide cofactor with reduced redox potential for biocatalysis 具有生物催化氧化还原电位的耐热人工烟酰胺辅助因子

IF 9.4

Chem Catalysis Pub Date : 2026-08-28 DOI: 10.1016/j.checat.2026.101838

Yuan Ji,Binbin Chen,Xun Yu,Yajie Wang

引用次数: 0

Spin-state engineering of atomic iron-based frustrated Lewis pairs for enhanced photocatalytic nitrogen fixation to ammonia 原子铁基受挫刘易斯对的自旋态工程增强光催化固氮对氨

IF 9.4

Chem Catalysis Pub Date : 2026-08-25 DOI: 10.1016/j.checat.2026.101835

Qiuhui Zhu,Xue Xiao,Aoxiang Song,Ximing Li,Yan Zhou,Haitao Ren,Jiapeng Hu,Chuanyi Wang

{"title":"Spin-state engineering of atomic iron-based frustrated Lewis pairs for enhanced photocatalytic nitrogen fixation to ammonia","authors":"Qiuhui Zhu,Xue Xiao,Aoxiang Song,Ximing Li,Yan Zhou,Haitao Ren,Jiapeng Hu,Chuanyi Wang","doi":"10.1016/j.checat.2026.101835","DOIUrl":"https://doi.org/10.1016/j.checat.2026.101835","url":null,"abstract":"Photocatalytic nitrogen fixation offers a sustainable alternative to the energy-intensive Haber-Bosch process but remains limited by inefficient N2 adsorption and activation. Here, we construct atomic iron (Fe)-based frustrated Lewis pairs (Fe···OHSA FLPs) on defective bismuth (Bi)/bismuth oxybromide (BiOBr), where isolated Fe sites and surface hydroxyl groups function as Lewis acid and Lewis base centers, respectively. Characterizations and theoretical calculations reveal that the Fe···OH FLPs synergistically strengthen N2 adsorption, facilitate N≡N activation, and promote proton-coupled electron transfer. Consequently, the optimized catalyst achieves an ammonia (NH3) production rate of 502.64 μmol g−1 h−1 under sacrificial-agent-free conditions, representing a 13.96-fold enhancement over BiOBr. Mechanistically, oxygen-vacancy-induced tetracoordinated Fe decreases the crystal-field splitting between the t2g and eg orbitals, forming a high-spin electronic configuration. The resulting enhanced Fe 3d-N2 2p orbital coupling promotes electron transfer into antibonding orbitals and accelerates N≡N bond cleavage. This work establishes spin-state engineering as an effective strategy for activating N2 on single-atom-based FLP photocatalysts.","PeriodicalId":53121,"journal":{"name":"Chem Catalysis","volume":"11 1","pages":""},"PeriodicalIF":9.4,"publicationDate":"2026-08-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148821601","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Electrochemical atom-transfer radical addition to [1.1.1]propellane for the synthesis of bench-stable BCP–Br linchpins 电化学原子转移自由基加入[1.1.1]推进剂合成台架稳定的BCP-Br关键销

IF 9.4

Chem Catalysis Pub Date : 2026-08-24 DOI: 10.1016/j.checat.2026.101834

Haifeng Chen,Chenxi Wu,Liang Yi,Magnus Rueping

{"title":"Electrochemical atom-transfer radical addition to [1.1.1]propellane for the synthesis of bench-stable BCP–Br linchpins","authors":"Haifeng Chen,Chenxi Wu,Liang Yi,Magnus Rueping","doi":"10.1016/j.checat.2026.101834","DOIUrl":"https://doi.org/10.1016/j.checat.2026.101834","url":null,"abstract":"Selective termination of carbon-centered radicals under electrochemical conditions remains challenging, particularly in strained systems where over-reduction and unselective quenching can compete with productive atom transfer. Herein, we report an electrochemically enabled atom-transfer radical bromoalkylation of [1.1.1]propellane that converts activated alkyl bromides into isolable, bench-stable 1-alkyl-3-bromobicyclo[1.1.1]pentanes. Constant-current electrolysis with a zinc anode, nickel-foam cathode, and tetrabutylammonium bromide electrolyte initiates alkyl radical formation while favoring bromine atom transfer to the bicyclopentyl radical intermediate. The reaction accommodates primary, secondary, and tertiary activated alkyl bromides, including complex drug-like substrates, and the resulting BCP–Br products undergo C-, B-, P-, Se-, O-, and N-functionalization. Mechanistic experiments, including radical-clock and radical-trapping studies, cyclic voltammetry, and charge analysis, are consistent with an electrochemically initiated ATRA chain. This method provides a modular entry to brominated BCP linchpins and illustrates how electrochemical initiation can guide radical reactivity in strained molecular scaffolds.","PeriodicalId":53121,"journal":{"name":"Chem Catalysis","volume":"53 1","pages":""},"PeriodicalIF":9.4,"publicationDate":"2026-08-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148806380","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0