Case Reports in Pulmonology最新文献

A Subtle Presentation of Pharyngitis and Pneumonia: Lemierre Syndrome. 咽炎和肺炎的微妙表现：勒米尔综合征。

Case Reports in Pulmonology Pub Date : 2025-04-15 eCollection Date: 2025-01-01 DOI: 10.1155/crpu/6371331

Federico Bellini, Valentino Allocca, Laura Aspidistria, Marco Farinatti, Ippolito Guzzinati, Marta Maria Daniele, Serena Casanova, Francesca Gasparini, Mara Nalin, Sara Saturni, Gian Luca Casoni

{"title":"A Subtle Presentation of Pharyngitis and Pneumonia: Lemierre Syndrome.","authors":"Federico Bellini, Valentino Allocca, Laura Aspidistria, Marco Farinatti, Ippolito Guzzinati, Marta Maria Daniele, Serena Casanova, Francesca Gasparini, Mara Nalin, Sara Saturni, Gian Luca Casoni","doi":"10.1155/crpu/6371331","DOIUrl":"https://doi.org/10.1155/crpu/6371331","url":null,"abstract":"Lemierre syndrome (LS) is a rare condition with an estimated incidence of 1-10/1,000,000 per year defined as a complication of an oral and nasopharyngeal infection with secondary septicemia leading to septic emboli and internal jugular vein thrombosis. This syndrome was first described by Andre' Lemierre in 1936, before the development of antibiotics. In the preantibiotic era, it was a common condition and it was often characterized by a fatal course within 7-15 days with a mortality rate that could reach up to 80% of cases. After the development of antibiotic therapies, the incidence of LS rapidly declined, and nowadays, it is also known as \"the forgotten disease,\" but the mortality risk remains high (5%) especially in case of diagnostic delay and inappropriate therapies. We presented a case of a 23-year-old who was referred to our hospital for worsening dyspnea associated with high fever following a pharyngitis in order to raise awareness about this severe rare disease. Long-term outcomes are usually good if proper treatment is started with no delay. The mainstays of treatment for the pulmonary and vascular aspects are antibiotic treatment with or without anticoagulation and chest-tube drainage.","PeriodicalId":52364,"journal":{"name":"Case Reports in Pulmonology","volume":"2025 ","pages":"6371331"},"PeriodicalIF":0.0,"publicationDate":"2025-04-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12014257/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144055577","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Delayed-Onset Hemothorax Following Cough-Induced Rib Fracture. 咳嗽致肋骨骨折后迟发性血胸。

Case Reports in Pulmonology Pub Date : 2025-04-03 eCollection Date: 2025-01-01 DOI: 10.1155/crpu/7977884

Katrina Villegas Md, Arielle Aiken Md, Mohammed Halabiya Md, Mourad Ismail Md

{"title":"Delayed-Onset Hemothorax Following Cough-Induced Rib Fracture.","authors":"Katrina Villegas Md, Arielle Aiken Md, Mohammed Halabiya Md, Mourad Ismail Md","doi":"10.1155/crpu/7977884","DOIUrl":"https://doi.org/10.1155/crpu/7977884","url":null,"abstract":"Hemothorax, the accumulation of blood in the pleural space, is most frequently linked to chest trauma but can occasionally result from nontraumatic causes such as persistent or forceful coughing. Cough-induced rib fractures are rare, with an even less frequent association with hemothorax. We describe a case involving a 57-year-old male who presented with a worsening cough and left-sided pleuritic chest pain despite prior antibiotic and symptomatic treatment. Initial imaging revealed a minimally displaced 10th rib fracture, left-sided atelectasis, and trace pleural effusion. During his hospital stay, he developed acute respiratory distress and increased chest pain, with repeat imaging revealing a large left-sided hemothorax. Chest tube placement drained 1100 mL of blood, supporting the diagnosis of hemothorax, as evidenced by clinical presentation and imaging, despite the absence of fluid analysis. The patient's condition improved following the intervention, and he was discharged in stable condition without recurrence of hemothorax on follow-up imaging. This case highlights the rare association between cough-induced traumatic rib fractures and delayed development of hemothorax. While rib fractures typically result from blunt trauma, they can also occur from stress or repetitive coughing. Complications such as hemothorax are uncommon but potentially life-threatening. The interval development of hemothorax, as seen in this patient, underscores the importance of serial monitoring in cases of rib fractures with ongoing symptoms. Clinicians should maintain a high index of suspicion for hemothorax in patients presenting with rib fractures and persistent cough, particularly in the context of worsening respiratory symptoms or pleuritic chest pain. Early recognition and timely intervention are critical to optimizing outcomes and mitigating the risks of rapid clinical deterioration.","PeriodicalId":52364,"journal":{"name":"Case Reports in Pulmonology","volume":"2025 ","pages":"7977884"},"PeriodicalIF":0.0,"publicationDate":"2025-04-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11991826/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144007982","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The Unwelcome Guest: Strongyloides stercoralis Hyperinfection in a Patient With Steroid-Dependent Asthma-COPD Overlap Syndrome (ACOS)-A Case Report and Review of Literature. 不受欢迎的客人：类固醇依赖性哮喘-慢性阻塞性肺病重叠综合征（ACOS）患者的粪类圆线虫过度感染- 1例报告和文献复习。

Case Reports in Pulmonology Pub Date : 2025-03-19 eCollection Date: 2025-01-01 DOI: 10.1155/crpu/3204304

Rafael Miret, Jose M Acosta-Rullan, Alfredo Toll, Grayson Honeycutt, Manjot Malhi, Christian Almanzar Zorrilla, Raiko Diaz, Mauricio Danckers, Daniel Zapata

{"title":"The Unwelcome Guest: Strongyloides stercoralis Hyperinfection in a Patient With Steroid-Dependent Asthma-COPD Overlap Syndrome (ACOS)-A Case Report and Review of Literature.","authors":"Rafael Miret, Jose M Acosta-Rullan, Alfredo Toll, Grayson Honeycutt, Manjot Malhi, Christian Almanzar Zorrilla, Raiko Diaz, Mauricio Danckers, Daniel Zapata","doi":"10.1155/crpu/3204304","DOIUrl":"10.1155/crpu/3204304","url":null,"abstract":"Strongyloides stercoralis is a soil-transmitted roundworm nematode estimated to affect over 600 million people worldwide. Hyperinfection syndrome (HS) has been described in immunosuppressed patients. Our case highlights a rare manifestation of HS due to Strongyloides stercoralis causing acute respiratory failure in an asthma-COPD overlap syndrome (ACOS) patient on chronic corticosteroid therapy. A 63-year-old woman with diabetes, chronic obstructive pulmonary disorder due to chronic cigarette smoking, and severe asthma on chronic prednisone therapy presented with recurrent intractable abdominal pain and shortness of breath. The patient underwent esophagogastroduodenoscopy (EGD) showing friable mucosa returning positive for Strongyloides stercoralis infection. The patient deteriorated with progressive acute hypoxic respiratory failure and acute metabolic encephalopathy requiring invasive mechanical ventilation. Dual antiparasitic therapy with ivermectin and albendazole was initiated, and the patient was treated for septic shock. The patient was successfully extubated and was discharged from the hospital to a rehabilitation center without steroid therapy. Due to the classic transmission and life cycle of the filiform larvae, the lungs are target organs in HS. The mortality of Strongyloides HS ranges from 85% to 100% when untreated. HS due to Strongyloides stercoralis carries a high risk for disseminated infection in patients with chronic steroids. High index of suspicion, tissue sample, and prompt institution of target therapy institutions are key for a successful clinical outcome.","PeriodicalId":52364,"journal":{"name":"Case Reports in Pulmonology","volume":"2025 ","pages":"3204304"},"PeriodicalIF":0.0,"publicationDate":"2025-03-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11944777/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143721689","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Diffuse Alveolar Hemorrhage Associated With Anti-PL-7 Antisynthetase Syndrome: A Case Report. 弥漫性肺泡出血伴抗pl -7抗合成酶综合征1例报告。

Case Reports in Pulmonology Pub Date : 2025-01-17 eCollection Date: 2025-01-01 DOI: 10.1155/crpu/3715449

Paul Shiu, Shannon Iriza, Steven Templeton

{"title":"Diffuse Alveolar Hemorrhage Associated With Anti-PL-7 Antisynthetase Syndrome: A Case Report.","authors":"Paul Shiu, Shannon Iriza, Steven Templeton","doi":"10.1155/crpu/3715449","DOIUrl":"10.1155/crpu/3715449","url":null,"abstract":"Background: Diffuse alveolar hemorrhage (DAH) is a potentially life-threatening condition which can present with hemoptysis, diffuse alveolar infiltrates, anemia, and hypoxic respiratory failure. Antisynthetase syndrome (AS) is a rare autoimmune disorder most often characterized by nonerosive arthritis, proximal muscle weakness with elevated muscle enzymes, Raynaud's phenomenon, hyperkeratosis of the digits (mechanic's hands), and interstitial lung disease. According to large population studies, AS has an annual incidence of 0.56 per 100,000 persons and prevalence of 9 per 100,000. The most common autoantibody is anti-aminoacyl-transfer RNA synthetase for histidine (anti-Jo-1) with a reported prevalence of 20%-30%, whereas anti-Pl-7 (for threonine) accounts for less than 5% of all autoimmune myositis. Specific myositis autoantibodies determine clinical phenotype. PL-7 is characterized by interstitial lung disease, myositis, and arthritis. Autoimmune myositis, specifically AS, is a rare cause of DAH. Herein, we describe the first reported case of PL-7-associated AS with DAH. Case Presentation: A 41-year-old female presented with worsening shortness of breath and hemoptysis. Laboratory studies included a hemoglobin of 10.5 g/dL, mildly elevated liver enzymes, and a creatine phosphokinase (CPK) of nearly 4000 U/L. CT of the chest showed diffuse ground glass opacities bilaterally. Serial aliquots of the bronchoalveolar lavage (BAL) fluid revealed progressively hemorrhagic return and histopathologic analysis consistent with DAH. Other concurrent causes of DAH were ruled out. Conclusion: Although rare, AS should be considered a cause of DAH, particularly in patients presenting with symptoms of muscle weakness and arthritis or with evidence of mechanic's hands.","PeriodicalId":52364,"journal":{"name":"Case Reports in Pulmonology","volume":"2025 ","pages":"3715449"},"PeriodicalIF":0.0,"publicationDate":"2025-01-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11759568/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143048610","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Brown-Colored Malignant Pleural Fluid With High Bilirubin Levels: A Case Series. 高胆红素水平的棕色恶性胸腔积液：病例系列。

Case Reports in Pulmonology Pub Date : 2024-11-18 eCollection Date: 2024-01-01 DOI: 10.1155/crpu/5807681

Nai-Chien Huan, Larry Ellee Nyanti, Xin Ying Lee, Hema Yamini Ramarmuty, Daniel Theng Sheng Eng, Kunji Kannan Sivaraman Kannan, Yun Chor Gary Lee

引用次数: 0

A Rare Case of Tracheal Schwannoma Successfully Treated With Endoscopic Resection and Cryoablation Under Rigid Bronchoscopy. 在硬质支气管镜下通过内窥镜切除和冷冻消融成功治疗气管许旺瘤的罕见病例

Case Reports in Pulmonology Pub Date : 2024-10-16 eCollection Date: 2024-01-01 DOI: 10.1155/2024/2961560

Ming Chiu Chan, Cheuk Cheung Derek Leung, Yu Hong Chan, Man Ying Ho, Chun Hoi Chen, Ching Man Ngai, Hiu Ching Christy Chan, Yiu Cheong Yeung

{"title":"A Rare Case of Tracheal Schwannoma Successfully Treated With Endoscopic Resection and Cryoablation Under Rigid Bronchoscopy.","authors":"Ming Chiu Chan, Cheuk Cheung Derek Leung, Yu Hong Chan, Man Ying Ho, Chun Hoi Chen, Ching Man Ngai, Hiu Ching Christy Chan, Yiu Cheong Yeung","doi":"10.1155/2024/2961560","DOIUrl":"https://doi.org/10.1155/2024/2961560","url":null,"abstract":"We present a rare case of tracheal schwannoma, the first reported in Hong Kong, emphasizing the diagnostic challenges and treatment outcomes. A 54-year-old woman with respiratory symptoms underwent evaluations revealing a tracheal mass causing luminal narrowing. Emergency operation with rigid bronchoscopy and cryoablation successfully removed the tumor. Follow-up bronchoscopies showed a gradual reduction in residual tumor size, with no evidence of recurrence after 3.5 years postoperation. Tracheal schwannomas are exceedingly rare, often resulting in delayed diagnosis. Clinicians should maintain a high suspicion of tracheal tumors in patients with unexplained respiratory symptoms. Spirometry and flow volume loop analysis aid in identifying upper airway obstruction. Rigid bronchoscopy is preferred for diagnosis and treatment, ensuring airway stability and obtaining tissue samples. Surgical resection remains the mainstay, but observation after endoscopic resection may be considered. This case highlights the successful management of tracheal schwannoma through endoscopic resection and cryoablation, emphasizing the need for further studies and case reports on this rare entity.","PeriodicalId":52364,"journal":{"name":"Case Reports in Pulmonology","volume":"2024 ","pages":"2961560"},"PeriodicalIF":0.0,"publicationDate":"2024-10-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11498987/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142512763","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Malignant Airway Stenosis Successfully Treated Using a Combination of Interventional Pulmonology, Chemotherapy, and Radiotherapy. 采用介入肺科、化疗和放疗联合疗法成功治疗恶性气道狭窄。

Case Reports in Pulmonology Pub Date : 2024-09-12 eCollection Date: 2024-01-01 DOI: 10.1155/2024/6779155

Jose N Sancho-Chust, Anastasiya Torba, Eusebi Chiner

引用次数: 0

Acute Myocardial Infarction in the Setting of Pulmonary Hypertension due to a Patent Foramen Ovale and Paradoxical Embolism. 因卵圆孔未闭和矛盾栓塞导致肺动脉高压的急性心肌梗死。

Case Reports in Pulmonology Pub Date : 2024-07-18 eCollection Date: 2024-01-01 DOI: 10.1155/2024/6725308

Madeline Franke, Zeenat Safdar

引用次数: 0

Endobronchial Infection and Bacterial Lymphadenitis by Gemella morbillorum Leading to Airway Perforation and a Bronchopleural Fistula. 支气管内膜感染和细菌性淋巴结炎导致气道穿孔和支气管胸膜瘘。

Case Reports in Pulmonology Pub Date : 2024-07-17 eCollection Date: 2024-01-01 DOI: 10.1155/2024/8850287

Kaitlin N DePrez, John Ferguson

{"title":"Endobronchial Infection and Bacterial Lymphadenitis by Gemella morbillorum Leading to Airway Perforation and a Bronchopleural Fistula.","authors":"Kaitlin N DePrez, John Ferguson","doi":"10.1155/2024/8850287","DOIUrl":"https://doi.org/10.1155/2024/8850287","url":null,"abstract":"Introduction: Necrotizing bronchial infection with severe infectious lymphadenitis is infrequently encountered and most commonly ascribed to Aspergillus, Histoplasma, and Mycobacterium species. We present a unique cause of severe airway destruction with lymphadenitis and bronchopleural fistula formation by the bacterium Gemella morbillorum. Case: A 24-year-old man presented with acute symptoms of vomiting, fever, and shoulder pain. A CT of the chest demonstrated a large subcarinal mass encasing the central bronchi. The workup for malignant, fungal, and granulomatous etiologies was unrevealing, while blood cultures identified G. morbillorum. Fiberoptic bronchoscopy revealed a perforation of the right middle lobar bronchus and the formation of a bronchopleural fistula, resulting in a large hydropneumothorax with empyema. Despite antibiotic therapy, surgical intervention to repair the fistula, and ventilatory support, the progression of the bronchopleural fistula led to fatal respiratory failure. Conclusion: In cases of severe mediastinal adenopathy in a young patient, bacterial lymphadenitis should be considered in the differential diagnosis with lymphoma, germ cell tumor, granulomatosis with polyangiitis, sarcoidosis, histoplasmosis, and inflammatory myofibroblastic tumor.","PeriodicalId":52364,"journal":{"name":"Case Reports in Pulmonology","volume":"2024 ","pages":"8850287"},"PeriodicalIF":0.0,"publicationDate":"2024-07-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11268966/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141762568","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Rare Combined Congenital Pulmonary and Cardiovascular Malformations Revealed by Acute Hemoptysis. 急性咯血揭示的罕见先天性肺部和心血管畸形合并症

Case Reports in Pulmonology Pub Date : 2024-05-09 eCollection Date: 2024-01-01 DOI: 10.1155/2024/1428495

Dima Siblani, Ghassan Abi Chedid, Samir Challita, Sylvana El Zoghbi, Béatrice Le Bon Chami

{"title":"Rare Combined Congenital Pulmonary and Cardiovascular Malformations Revealed by Acute Hemoptysis.","authors":"Dima Siblani, Ghassan Abi Chedid, Samir Challita, Sylvana El Zoghbi, Béatrice Le Bon Chami","doi":"10.1155/2024/1428495","DOIUrl":"https://doi.org/10.1155/2024/1428495","url":null,"abstract":"Background: Lung sequestration is a subtype of congenital lung malformations; it is infrequently diagnosed in adults and is a rare cause of hemoptysis. The typical management of symptomatic lung sequestration is usually surgical, though intra-arterial embolization is becoming an acceptable alternative. Case Presentation. We report a case of a 36-year-old female patient who presented for an acute onset of hemoptysis. CT chest showed an intralobar sequestration of the right lower lobe lung segment. In addition to the sequestration, the chest imaging also revealed a number of associated abnormalities including double superior vena cava communicating through a bridge, absence of brachiocephalic venous trunk, cardiac dextroposition, and agenesis of the right middle lobe. Outcome and Discussion. The transarterial embolization was selected for being mini-invasive and effective. It successfully controlled the bleed and led to complete regression of the sequestered lung on the follow-up CT chest several months later.Conclusion: Successful management and complete regression are possible with mini-invasive intra-arterial embolization of lung sequestration. Although it is not uncommon to have associated congenital cardiopulmonary abnormalities with lung sequestration, however the exceptional abnormalities described in this case have never been reported before.","PeriodicalId":52364,"journal":{"name":"Case Reports in Pulmonology","volume":"2024 ","pages":"1428495"},"PeriodicalIF":0.0,"publicationDate":"2024-05-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11098605/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140960880","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0