Case Reports in Pulmonology最新文献

{"title":"Relatively Benign Clinical Course of Acute Pneumonitis After Pleurodesis Using <i>Viscum album</i> Extract in Very Elderly Patient.","authors":"Jaejun Jeong, Min Kyun Kang","doi":"10.1155/crpu/5682658","DOIUrl":"10.1155/crpu/5682658","url":null,"abstract":"<p><p>Secondary spontaneous pneumothorax in elderly patients is often challenging to treat surgically; hence, conservative management strategies, such as chemical pleurodesis, are frequently utilized. <i>Viscum album</i> extract is an established sclerosing agent used for pleurodesis, though some studies have reported associated complications, including acute pneumonitis. Here, we report the case of a 93-year-old male with secondary spontaneous pneumothorax who developed acute chemical pneumonitis following pleurodesis with <i>V. album</i> extract. Despite the initial radiologic severity, the patient was successfully managed and exhibited a benign clinical course.</p>","PeriodicalId":52364,"journal":{"name":"Case Reports in Pulmonology","volume":"2026 ","pages":"5682658"},"PeriodicalIF":0.0,"publicationDate":"2026-09-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13613023/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149065892","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Inflammatory Myofibroblastic Tumor of the Central Airways: Case Report and Review of Diagnostic and Therapeutic Strategies.","authors":"Ahmed Ehab, Naoufal Benabdallah, Ibrahim Yasin, Ulrich Klein, Erik Büscher, Arndt Borkhardt, Kaid Darwiche","doi":"10.1155/crpu/3123893","DOIUrl":"10.1155/crpu/3123893","url":null,"abstract":"<p><p>Inflammatory myofibroblastic tumors (IMTs) are rare mesenchymal neoplasms with intermediate malignant potential. While most commonly arising in the lung, airway involvement is exceedingly uncommon. Endobronchial IMTs typically manifest with symptoms of airway obstruction, including dyspnea, wheezing, and stridor. Diagnosis involves radiological imaging, bronchoscopic evaluation, and histopathological analysis. Additionally, assessment of anaplastic lymphoma kinase (ALK) status is particularly important in young and pediatric patients, as ALK-targeted therapies constitute a viable treatment option for tumors harboring ALK rearrangements or other actionable kinase fusions. Complete surgical resection remains the gold standard for treatment; however, bronchoscopic resection may be an effective option in selected cases. Herein, we describe two cases of IMTs involving the airways-one in an adult and one in a child-both presenting with significant airway obstruction and managed with bronchoscopic resection.</p>","PeriodicalId":52364,"journal":{"name":"Case Reports in Pulmonology","volume":"2026 ","pages":"3123893"},"PeriodicalIF":0.0,"publicationDate":"2026-09-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13535852/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148882701","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Multidisciplinary Management of Lymphangioleiomyomatosis Presenting With Severe Bilateral Pneumothorax During Pregnancy: A Case Report.","authors":"Shiva Ebrahimi, Ali Abdollahzadeh, Maryam Barghaman, Amirhossein Hajialigol","doi":"10.1155/crpu/5512688","DOIUrl":"10.1155/crpu/5512688","url":null,"abstract":"<p><strong>Introduction: </strong>Lymphangioleiomyomatosis (LAM) is a rare, progressive, multisystem disease primarily affecting women of reproductive age. It is characterized by the abnormal proliferation of smooth muscle-like LAM cells that infiltrate the lungs, lymphatics, and kidneys. This case highlights that the clinical value lies not in isolated features, but in the convergence of early gestational presentation, severe bilateral disease, diagnostic limitations, and the need for coordinated multidisciplinary decision-making in a resource-constrained setting.</p><p><strong>Case presentation: </strong>A 23-year-old pregnant woman (G3P2L1A1) at 17 weeks of gestation presented with severe shortness of breath and bilateral shoulder pain, escalating to respiratory distress (SpO2 80%) and functional class IV within hours. Imaging revealed bilateral pneumothorax, near-complete lung collapse, and multiple small cysts in the lung parenchyma, suggestive of LAM. Chest tube placement and pulmonary consultations were performed, followed by a control CT scan confirming LAM. Because of the risk of worsening LAM during pregnancy, termination of the pregnancy was carried out, and diagnostic confirmation was achieved through video-assisted thoracoscopic surgery (VATS) with lung biopsy, showing cystic and adhesive lesions. Treatment included decortication, lesion removal, and sirolimus therapy, an mTOR inhibitor. The patient was discharged in stable condition with ongoing medical follow-up.</p><p><strong>Conclusion: </strong>Management of LAM during pregnancy requires a multidisciplinary approach, emphasizing personalized care to balance maternal and fetal health. This case highlights the need for vigilance and adaptability in the care of pregnant women with rare pulmonary disorders like LAM. Early diagnosis is key to slowing the progressive decline of pulmonary function. Further research is needed to improve treatment options for LAM patients.</p>","PeriodicalId":52364,"journal":{"name":"Case Reports in Pulmonology","volume":"2026 ","pages":"5512688"},"PeriodicalIF":0.0,"publicationDate":"2026-08-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13530389/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148876497","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Solitary Fibrous Tumors of the Pleura With Extensive Intrathoracic Occupation: Report of Two Cases.","authors":"Renzo Villanueva-Villegas, Cristian Morán-Mariños, Ruth Huaman-Achahui, Claudia Melendez-Davila, Briam Benito-Condor, José Monroy-Palomino","doi":"10.1155/crpu/8899120","DOIUrl":"10.1155/crpu/8899120","url":null,"abstract":"<p><p>Solitary fibrous tumors of the pleura (SFTPs) are rare mesenchymal neoplasms that typically originate from the visceral pleura. We report two cases of giant pleural SFTs involving the left hemithorax. The first case involved a 59-year-old woman presenting with two synchronous tumors, whereas the second case concerned a 39-year-old man with a single large intrathoracic mass. The coexistence of two distinct SFTs within the same hemithorax, as observed in the first patient, is exceptionally rare and may suggest a multicentric pleural origin or intrapleural dissemination. Both patients presented with progressive respiratory symptoms and mediastinal shift on chest computed tomography. Histopathological diagnosis was confirmed by percutaneous biopsy and immunohistochemical positivity for CD34, CD99, and BCL2. Complete tumor resection was achieved through posterolateral thoracotomy in both cases. One patient developed early postoperative recurrence during follow-up. These cases highlight the clinical heterogeneity of pleural SFTs and emphasize the diagnostic and surgical challenges posed by giant intrathoracic tumors. Accurate histopathological confirmation and complete surgical resection remain essential for optimal management, whereas long-term surveillance is warranted due to the potential risk of recurrence.</p>","PeriodicalId":52364,"journal":{"name":"Case Reports in Pulmonology","volume":"2026 ","pages":"8899120"},"PeriodicalIF":0.0,"publicationDate":"2026-08-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13523727/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148851871","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Epithelioid Angiosarcoma Presenting With Bilateral Hemothorax and Hemoptysis: A Case Report.","authors":"Simon Ståhl, Christina Triantafyllidou, Petros Effraimidis, Simone Ignatova, Johan Asplund, Erica Holmberg, Jonas Agholme","doi":"10.1155/crpu/6324954","DOIUrl":"10.1155/crpu/6324954","url":null,"abstract":"<p><p>We report a case of a 77-year-old man presenting with bilateral hemothorax, hemoptysis, and multiple bilateral pulmonary nodules and lung infiltrates. Histopathological and immunohistochemical analysis of a surgically resected nodule revealed epithelioid angiosarcoma, and the overall radiological and operative findings favored pulmonary origin. No other primary sites outside the thorax could be identified. The patient was planned for palliative chemotherapy, but his condition deteriorated, and he died before treatment could be initiated. Angiosarcoma is a rare and highly aggressive endothelial malignancy, most commonly affecting the skin and subcutaneous tissue of the head and neck. Primary pulmonary angiosarcoma is extremely uncommon; pulmonary involvement more often occurs through metastatic spread. When angiosarcoma involves the lungs as a primary neoplasm, it may present with multiple nodules, hemorrhagic lesions, or diffuse infiltrative patterns, frequently leading to hemoptysis and respiratory symptoms. Clinical course can be rapid, and prognosis is poor, particularly in advanced thoracic disease.</p>","PeriodicalId":52364,"journal":{"name":"Case Reports in Pulmonology","volume":"2026 ","pages":"6324954"},"PeriodicalIF":0.0,"publicationDate":"2026-08-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13494510/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148801499","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Diagnosing Congenital Diaphragmatic Eventration Presenting With Transient Cardiac Dextroposition in an Adult: A Case Report and Literature Review.","authors":"Yeganeh Rafiei, Behnaz Movahedi, Fatemeh Bayat, Fatemeh Zohrian","doi":"10.1155/crpu/1851328","DOIUrl":"10.1155/crpu/1851328","url":null,"abstract":"<p><p>Congenital diaphragmatic eventration (CDE) is a rare developmental anomaly characterized by abnormal elevation of an intact hemidiaphragm due to deficient muscular development. Although often asymptomatic in adults, it may present with respiratory or gastrointestinal complaints. We report a 65-year-old man with congenital left hemidiaphragmatic eventration associated with gastric displacement and colonic interposition. He initially presented with chest pain and was found to have cardiac dextroposition. Multimodality imaging, including fluoroscopy, demonstrated a transient rightward cardiac displacement that became more apparent after postprandial gastric distention and regressed as gastric decompression occurred. This dynamic finding suggests that gastrointestinal distention and associated mass effect can exacerbate mediastinal displacement in patients with CDE. This case highlights the importance of considering congenital diaphragmatic anomalies in adults with atypical chest symptoms and emphasizes the value of dynamic imaging in clarifying reversible cardiac displacement.</p>","PeriodicalId":52364,"journal":{"name":"Case Reports in Pulmonology","volume":"2026 ","pages":"1851328"},"PeriodicalIF":0.0,"publicationDate":"2026-08-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13439979/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148680503","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Case Report: Endobronchial Foreign Body Retrieved via Flexible Bronchoscopy 51 Years After Initial Aspiration.","authors":"Saif-El-Din El-Akkad, Michael Brown, Renelle Myers","doi":"10.1155/crpu/9666495","DOIUrl":"10.1155/crpu/9666495","url":null,"abstract":"<p><p>Undiagnosed and retained aspirated foreign bodies are a well-recognized cause of pulmonary morbidity, yet diagnosis of this clinical entity is often delayed, particularly when the foreign body is radiolucent, or the history of aspiration cannot be recalled. We report the longest documented case of a retained airway foreign body to date: a 59-year-old woman who aspirated a plastic Barbie doll house cup at age 8, 51 years prior. She experienced recurrent right lower lobe (RLL) pneumonias, and CT imaging eventually revealed chronic RLL collapse and bronchial obstruction. Flexible bronchoscopy confirmed and enabled successful removal of the foreign body. This case underscores the importance of maintaining clinical suspicion for foreign body aspiration in adults with persistent or recurrent respiratory symptoms, even when the initial aspiration event occurred many years prior. It also highlights the diagnostic challenges associated with radiolucent foreign bodies and the potential for long-term pulmonary complications when diagnosis is delayed.</p>","PeriodicalId":52364,"journal":{"name":"Case Reports in Pulmonology","volume":"2026 ","pages":"9666495"},"PeriodicalIF":0.0,"publicationDate":"2026-08-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13430971/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148671494","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Progressive Fibrosing Lung Disease Treated With Nintedanib in a Patient With Long-Standing Autoimmune Pulmonary Alveolar Proteinosis: A Case Report.","authors":"Yoshiaki Zaizen, Yasuhiko Nikaido, Takeo Jimi, Tetsuya Kawano, Katsuyuki Ichiki, Toru Tsuda, Tomoaki Hoshino","doi":"10.1155/crpu/8073947","DOIUrl":"10.1155/crpu/8073947","url":null,"abstract":"<p><strong>Background: </strong>Autoimmune pulmonary alveolar proteinosis (APAP) is caused by impaired surfactant clearance due to neutralizing autoantibodies against granulocyte-macrophage colony-stimulating factor. Although whole-lung lavage and inhaled granulocyte-macrophage colony-stimulating factor therapy are established treatment options, pulmonary fibrosis is increasingly recognized as a clinically relevant complication in a subset of patients with APAP. However, the clinical behavior of APAP-associated fibrosing lung disease and the role of antifibrotic therapy remain unclear.</p><p><strong>Case presentation: </strong>A 54-year-old man with a 15-year history of APAP was referred to our institution. High-resolution computed tomography images obtained before referral showed slow progression of reticulation and traction bronchiectasis, suggesting fibrotic progression rather than recurrence of APAP. At presentation, forced vital capacity (FVC) was 3.31 L (80.0% predicted), and diffusion capacity for carbon monoxide (DL_CO) was preserved. During 6 months of observation, FVC declined to 3.03 L (73.5% predicted), accompanied by worsening dry cough and exertional dyspnea. Nintedanib was initiated for a progressive fibrosing phenotype in the context of APAP. Thereafter, FVC remained relatively stable for 2 years, whereas DL_CO declined during follow-up.</p><p><strong>Conclusions: </strong>APAP-associated fibrosing lung disease may present with a progressive fibrosing phenotype, but its diagnosis and management remain challenging. This case highlights the importance of distinguishing fibrotic progression from recurrence of intra-alveolar proteinosis.</p>","PeriodicalId":52364,"journal":{"name":"Case Reports in Pulmonology","volume":"2026 ","pages":"8073947"},"PeriodicalIF":0.0,"publicationDate":"2026-07-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13428075/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148655039","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Life-Threatening Acute Hypoxemic Respiratory Failure Caused by Complete Left Lung Collapse Secondary to Mucus Plug Obstruction in a Toddler: A Case Report.","authors":"Menghak Heng, Chhayhout Chheang, Sophou Chit, Bunleng Kou, Kimhun Ton, Sarin Ean, Chheang Khor, Borin Hem, Vibopha Srey, Sopheak Phy, Heng Leang, Bunpaul Chhar","doi":"10.1155/crpu/3939387","DOIUrl":"10.1155/crpu/3939387","url":null,"abstract":"<p><p>Acute hypoxemic respiratory failure in toddlers is most commonly associated with severe pneumonia, bronchiolitis, or foreign body aspiration. Complete obstruction of a main bronchus by mucus plugs is an uncommon but potentially life-threatening cause of unilateral lung collapse and severe hypoxemia. We report the case of a previously healthy 17-month-old boy who presented with severe respiratory distress after 3 days of fever and cough. Physical examination revealed marked respiratory distress with absent breath sounds over the left hemithorax. Chest radiography and computed tomography demonstrated complete left lung collapse without evidence of pleural effusion or foreign body. Due to rapidly worsening hypoxemia and suspected central airway obstruction, emergency flexible bronchoscopy was performed under general anesthesia via endotracheal intubation. Complete occlusion of the left main bronchus by thick mucus plugs was identified and successfully removed using suction and bronchoscopic forceps, resulting in immediate improvement in oxygenation and rapid radiologic lung re-expansion. The patient recovered fully and was discharged in 5 days without complications. This case highlights the importance of considering mucus plug-induced bronchial obstruction in toddlers presenting with sudden unilateral lung collapse and severe hypoxemia, particularly when foreign body aspiration remains a differential diagnosis. Early bronchoscopic intervention can be lifesaving and may prevent prolonged respiratory failure and associated complications.</p>","PeriodicalId":52364,"journal":{"name":"Case Reports in Pulmonology","volume":"2026 ","pages":"3939387"},"PeriodicalIF":0.0,"publicationDate":"2026-07-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13382151/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148609554","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Correction to \"A Rare Case of Concurrent Urinothorax and Myelomatous Pleural Effusion\".","authors":"","doi":"10.1155/crpu/9861975","DOIUrl":"https://doi.org/10.1155/crpu/9861975","url":null,"abstract":"<p><p>[This corrects the article DOI: 10.1155/crpu/6880861.].</p>","PeriodicalId":52364,"journal":{"name":"Case Reports in Pulmonology","volume":"2026 ","pages":"9861975"},"PeriodicalIF":0.0,"publicationDate":"2026-07-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13333252/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148392399","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}