以双侧网状结节浸润为表现的原发性肺腺癌1例。

Q4 Medicine
Case Reports in Pulmonology Pub Date : 2025-06-09 eCollection Date: 2025-01-01 DOI:10.1155/crpu/6678388
Geran Maule, Qusai Alqudah, Mohamed Ismail, Ryan Fox, Ajaypal Gill, Luis Javier
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引用次数: 0

摘要

52岁女性,术后有胃食管反流病(GERD)、高血压(HTN)和室上性心动过速(SVT)病史,影像学表现为进行性呼吸困难和弥漫性双侧浸润。接触养鸡场后开始出现症状,最初为干咳,尽管接受了抗生素、沙丁胺醇和甲基强的松龙治疗,但病情仍在发展。急诊科CT显示双侧线状、网状及结节性浸润。阴性感染检查提示支气管镜检查,通过免疫组化染色确认肺腺癌,尽管没有明显的吸烟史、国际旅行或其他暴露。脑MRI发现一个孤立的7毫米增强病灶,指导后续的肿瘤治疗。本病例强调了诊断非典型肺部症状的复杂性,并提倡对疑似恶性肿瘤进行早期支气管镜检查,特别是有相关家族史的患者。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

Primary Lung Adenocarcinoma Manifesting as Bilateral Reticulonodular Infiltrates: A Case Report.

Primary Lung Adenocarcinoma Manifesting as Bilateral Reticulonodular Infiltrates: A Case Report.

Primary Lung Adenocarcinoma Manifesting as Bilateral Reticulonodular Infiltrates: A Case Report.

A 52-year-old female with a history of gastroesophageal reflux disease (GERD), hypertension (HTN), and supraventricular tachycardia (SVT) status postablation presented with progressive dyspnea and diffuse bilateral infiltrates on imaging. Symptoms began following exposure to a chicken farm, initially as a dry cough, evolving despite treatment with antibiotics, albuterol, and methylprednisolone. Emergency department CT imaging demonstrated bilateral linear, reticular, and nodular infiltrates. A negative infectious workup prompted bronchoscopy, confirming lung adenocarcinoma via immunohistochemical staining despite no significant smoking history, international travel, or other exposures. Brain MRI identified a solitary 7-mm enhancing lesion, guiding subsequent oncologic management. This case underscores the complexity of diagnosing atypical pulmonary symptoms and advocates for early bronchoscopic evaluation in suspected malignancies, particularly with pertinent family history.

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来源期刊
Case Reports in Pulmonology
Case Reports in Pulmonology Medicine-Pulmonary and Respiratory Medicine
CiteScore
1.80
自引率
0.00%
发文量
23
审稿时长
13 weeks
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