Journal of Medical Devices-Transactions of the Asme最新文献

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DynaRing: A Patient-Specific Mitral Annuloplasty Ring With Selective Stiffness Segments. 动态:一种具有选择性刚度节段的患者特异性二尖瓣成形术环。
IF 0.9 4区 医学
Journal of Medical Devices-Transactions of the Asme Pub Date : 2022-09-01 DOI: 10.1115/1.4054445
Samuel Frishman, Ali Kight, Ileana Pirozzi, Sainiteesh Maddineni, Annabel M Imbrie-Moore, Zulekha Karachiwalla, Michael J Paulsen, Alexander D Kaiser, Y Joseph Woo, Mark R Cutkosky
{"title":"DynaRing: A Patient-Specific Mitral Annuloplasty Ring With Selective Stiffness Segments.","authors":"Samuel Frishman,&nbsp;Ali Kight,&nbsp;Ileana Pirozzi,&nbsp;Sainiteesh Maddineni,&nbsp;Annabel M Imbrie-Moore,&nbsp;Zulekha Karachiwalla,&nbsp;Michael J Paulsen,&nbsp;Alexander D Kaiser,&nbsp;Y Joseph Woo,&nbsp;Mark R Cutkosky","doi":"10.1115/1.4054445","DOIUrl":"https://doi.org/10.1115/1.4054445","url":null,"abstract":"<p><p>Annuloplasty ring choice and design are critical to the long-term efficacy of mitral valve (MV) repair. DynaRing is a selectively compliant annuloplasty ring composed of varying stiffness elastomer segments, a shape-set nitinol core, and a cross diameter filament. The ring provides sufficient stiffness to stabilize a diseased annulus while allowing physiological annular dynamics. Moreover, adjusting elastomer properties provides a mechanism for effectively tuning key MV metrics to specific patients. We evaluate the ring embedded in porcine valves with an ex-vivo left heart simulator and perform a 150 million cycle fatigue test via a custom oscillatory system. We present a patient-specific design approach for determining ring parameters using a finite element model optimization and patient MRI data. Ex-vivo experiment results demonstrate that motion of DynaRing closely matches literature values for healthy annuli. Findings from the patient-specific optimization establish DynaRing's ability to adjust the anterior-posterior and intercommissural diameters and saddle height by up to 8.8%, 5.6%, 19.8%, respectively, and match a wide range of patient data.</p>","PeriodicalId":49305,"journal":{"name":"Journal of Medical Devices-Transactions of the Asme","volume":null,"pages":null},"PeriodicalIF":0.9,"publicationDate":"2022-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9125864/pdf/med-21-1009_031009.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10244895","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
On the Design and Testing of an Origami Inspired Nasal Cover: Mitigating Aerosol Risks During Endoscopic Sinus Procedures 折纸启发的鼻罩的设计和测试:降低鼻窦内窥镜手术中的气溶胶风险
IF 0.9 4区 医学
Journal of Medical Devices-Transactions of the Asme Pub Date : 2022-08-16 DOI: 10.1115/1.4055251
Evan Heatherington, Xiaoyue Zhao, N. Goyal, Z. Ounaies, M. Frecker
{"title":"On the Design and Testing of an Origami Inspired Nasal Cover: Mitigating Aerosol Risks During Endoscopic Sinus Procedures","authors":"Evan Heatherington, Xiaoyue Zhao, N. Goyal, Z. Ounaies, M. Frecker","doi":"10.1115/1.4055251","DOIUrl":"https://doi.org/10.1115/1.4055251","url":null,"abstract":"\u0000 Aerosols generated during endoscopic sinus procedures present a concern to the health and safety of healthcare personnel especially with the presence of COVID-19. The purpose of this study is to describe the design and testing of a nasal cover to restrict aerosolized pathogens. The nasal cover was designed to sit overtop the nose with conformal slits for insertion of endoscopic instrumentation. Polydimethylsiloxane (PDMS) was chosen as the nasal mask material and its composition, thickness, and slit geometry were selected using a Taguchi experimental design and survey with clinical collaborators at Penn State Milton S. Hershey Medical Center. The nasal cover was designed using principles of origami engineering to be manufactured flat then folded into its operating state. Form and functionality were evaluated by surgeons, fellows, and residents in the aforementioned survey. Aerosol containment was evaluated by measuring smoke, representative of surgical aerosols, with an optical particle counter. A 25:1 composition PDMS with 3mm thickness and vertical slit geometry was chosen for the nasal cover design. Survey results demonstrated that the origami cover sat well on the nose and did not significantly impact the surgical conditions with single instrumentation. On average, this nasal cover was found to restrict more than 93% of 0.3µm aerosols, and more than 99% of all aerosols larger than 0.5µm in size. Use of a patient worn nasal cover has the potential to drastically reduce the risk to hospital personnel during endonasal surgeries by reducing aerosol generation and potential pathogen spread.","PeriodicalId":49305,"journal":{"name":"Journal of Medical Devices-Transactions of the Asme","volume":null,"pages":null},"PeriodicalIF":0.9,"publicationDate":"2022-08-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46127152","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Microbiota Sampling Capsule: Design, Prototyping and Assessment of a Sealing Solution Based on a Bistable Mechanism 微生物取样胶囊:基于双稳态机制的密封溶液的设计、原型和评估
IF 0.9 4区 医学
Journal of Medical Devices-Transactions of the Asme Pub Date : 2022-08-16 DOI: 10.1115/1.4055250
Mouna Ben Salem, Guillaume Aiche, Y. Haddab, L. Rubbert, P. Renaud
{"title":"Microbiota Sampling Capsule: Design, Prototyping and Assessment of a Sealing Solution Based on a Bistable Mechanism","authors":"Mouna Ben Salem, Guillaume Aiche, Y. Haddab, L. Rubbert, P. Renaud","doi":"10.1115/1.4055250","DOIUrl":"https://doi.org/10.1115/1.4055250","url":null,"abstract":"\u0000 The diagnosis and the treatment of gastrointestinal pathologies have experienced significant development in recent years with the invention of endoscopic capsules which facilitate the access to different sections of the gastrointestinal tract. At a research level, the concept of capsules has been used to perform several functions such as gastrointestinal tract inspection and drug delivery. Despite that, microbiota sampling still requires surgery in order to collect intestinal liquid samples. In this paper, we propose a microbiota sampling device that navigates through the gastrointestinal tract, takes a sample of the intestinal liquid and protects it from any contamination as the device navigates out of the human body. We use a bistable structure to close the capsule after sampling actuated by a foam. The device is safe for the human body and eco friendly, as it does not contain electronic components, batteries and does not require any external intervention. To manufacture the microbiota sampling capsule, we use additive manufacturing. This technology allows fast prototyping cycle at a relatively low cost. It also offers the use of biocompatible material in advanced stages of development.","PeriodicalId":49305,"journal":{"name":"Journal of Medical Devices-Transactions of the Asme","volume":null,"pages":null},"PeriodicalIF":0.9,"publicationDate":"2022-08-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46347609","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
3D Printing in Combined Cartesian and Curvilinear Coordinates 笛卡尔坐标系和曲线坐标系下的三维打印
IF 0.9 4区 医学
Journal of Medical Devices-Transactions of the Asme Pub Date : 2022-07-23 DOI: 10.1115/1.4055064
Edward Shi, Leo Lou, Linnea Warburton, B. Rubinsky
{"title":"3D Printing in Combined Cartesian and Curvilinear Coordinates","authors":"Edward Shi, Leo Lou, Linnea Warburton, B. Rubinsky","doi":"10.1115/1.4055064","DOIUrl":"https://doi.org/10.1115/1.4055064","url":null,"abstract":"\u0000 A 3D printing technology that facilitates continuous printing along a combination of cartesian and curvilinear coordinates, designed for in vivo and in situ bioprinting is introduced. The combined cartesian/curvilinear printing head motion is accomplished by attaching a biomimetic, flexible, \"tendon cable\" soft robot arm to a conventional cartesian three axis 3D printing carousel. This allows printing along a combination of cartesian and curvilinear coordinates using five independent stepper motors controlled by an Arduino Uno with each motor requiring a microstep driver powered via a 12V power supply. Three of the independent motors control the printing head motion along conventional cartesian coordinates while two of the independent motors control the length of each pair of the four \"tendon cables\" which in turn controls the radius of curvature and the angle displacement of the soft printer head along two orthogonal planes. This combination imparts motion along six independent degrees of freedom in cartesian and curvilinear coordinates. The design of the system is described together with experimental results which demonstrate that this design can print continuously along curved and inclined surfaces while avoiding the \"staircase\" effect, which is typical of conventional three axis 3D printing along curvilinear surfaces.","PeriodicalId":49305,"journal":{"name":"Journal of Medical Devices-Transactions of the Asme","volume":null,"pages":null},"PeriodicalIF":0.9,"publicationDate":"2022-07-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42704362","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
Accuracy of an Apparatus for Measuring Glenoid Baseplate Micromotion in Reverse Shoulder Arthroplasty 反向肩关节置换术中关节盂底微运动测量仪的准确性
IF 0.9 4区 医学
Journal of Medical Devices-Transactions of the Asme Pub Date : 2022-07-22 DOI: 10.1115/1.4055063
L. Torkan, J. T. Bryant, R. Bicknell, H. Ploeg
{"title":"Accuracy of an Apparatus for Measuring Glenoid Baseplate Micromotion in Reverse Shoulder Arthroplasty","authors":"L. Torkan, J. T. Bryant, R. Bicknell, H. Ploeg","doi":"10.1115/1.4055063","DOIUrl":"https://doi.org/10.1115/1.4055063","url":null,"abstract":"\u0000 Reverse shoulder arthroplasty (RSA) is used to treat patients with cuff tear arthropathy. Loosening remains one of the principal modes of implant failure and the main complication leading to revision. Excess micromotion contributes to glenoid loosening. This study assessed the predictive accuracy of an experimental system designed to assess factors contributing to RSA glenoid baseplate micromotion. A half-fractional factorial experiment was designed to assess 4 factors: central element type (screw vs. peg), central element length (13.5 vs. 23.5 mm), anterior posterior peripheral screw type (locking vs. nonlocking) and cancellous bone density (10 vs. 25 pounds per cubic foot [pcf]). Four linear variable differential transducers (LVDTs) recorded micromotion from a stainless-steel disc surrounding a modified glenosphere. The displacements were used to interpolate micromotion at each of the respective peripheral screw positions. The mean absolute percentage error (MAPE) was used to determine the predictive accuracy and error range of the system. The MAPE for each condition ranged from 6.8% to 12.9% for an overall MAPE of (9.5&#177;0.9)%. The system had an error range of 2.7 &#181;m to 20.1 &#181;m, which was lower than those reported by prior studies using optical systems. One of the eight conditions had micromotion that exceeded 150 &#181;m. These findings support the use of displacement transducers, specifically LVDTs, as an accurate system for determining RSA baseplate micromotion in rigid polyurethane foam bone surrogates.","PeriodicalId":49305,"journal":{"name":"Journal of Medical Devices-Transactions of the Asme","volume":null,"pages":null},"PeriodicalIF":0.9,"publicationDate":"2022-07-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46742864","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Performance and Sensitivity Analysis of an Automated X-Ray Based Total Knee Replacement Mass-Customization Pipeline 基于x射线的全膝关节置换术批量定制管道的性能和灵敏度分析
IF 0.9 4区 医学
Journal of Medical Devices-Transactions of the Asme Pub Date : 2022-07-15 DOI: 10.1115/1.4055000
T. A. Burge, J. Jeffers, C. Myant
{"title":"Performance and Sensitivity Analysis of an Automated X-Ray Based Total Knee Replacement Mass-Customization Pipeline","authors":"T. A. Burge, J. Jeffers, C. Myant","doi":"10.1115/1.4055000","DOIUrl":"https://doi.org/10.1115/1.4055000","url":null,"abstract":"\u0000 A proof-of-concept, fully automated, mass-customization pipeline for knee replacement surgery is outlined. The pipeline aims to address the limitations of currently available customization solutions by removing the need for 3D imaging and manual design, minimizing lead times, and reducing costs, whilst enabling improved patient outcomes.\u0000 The dataflow of the pipeline and methods for assessing performance are detailed. A digitally reconstructed radiograph method was adopted in the analysis to remove errors stemming from poor X-ray alignment and calibration, and to enable the influence of specific attributes to be evaluated. A sensitivity study was performed to quantify the impact of X-ray alignment and calibration.\u0000 The analysis found better results were achieved for the tibia over the femur in terms of clinically significant component over/under-hang (9% vs 18%). The pipeline was sensitive to subject ethnicity, but this was likely due to limited diversity in the training data. Arthritis severity was found to impact performance, suggesting further work is required to confirm suitability for use with more severe cases. X-ray alignment and dimensional calibration were shown to be paramount for accurate results. The pipeline performance was demonstrated to be superior to results reported for off-the-shelf implants, but customization solutions based on 3D imaging could afford marginally better results.\u0000 In summary, the study validated the pipeline for a broad range of subjects, highlighted its potential advantages over both off-the-shelf and other customization alternatives, and outlined the potential challenges of adopting such a tool.","PeriodicalId":49305,"journal":{"name":"Journal of Medical Devices-Transactions of the Asme","volume":null,"pages":null},"PeriodicalIF":0.9,"publicationDate":"2022-07-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48801554","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
A Novel Low-Cost 3D Printed Brace Design Method for Early Onset Scoliosis 一种治疗早期脊柱侧凸的低成本3D打印支架设计方法
IF 0.9 4区 医学
Journal of Medical Devices-Transactions of the Asme Pub Date : 2022-07-15 DOI: 10.1115/1.4054998
Hongwei Li, Zhangkai Yang, Dichen Li, F. Qiao
{"title":"A Novel Low-Cost 3D Printed Brace Design Method for Early Onset Scoliosis","authors":"Hongwei Li, Zhangkai Yang, Dichen Li, F. Qiao","doi":"10.1115/1.4054998","DOIUrl":"https://doi.org/10.1115/1.4054998","url":null,"abstract":"\u0000 Early onset scoliosis (EOS) is a type of spine deformity that presents before 10 years of age. The biomechanical properties in scoliosis have been found to be di?erent, especially in the case of the concave and convex paraverte-bral muscles. Based on this fact, a novel 3d printed patient-specific asymmetric stiffness brace design method is proposed in this paper, aiming to provide asymmetric stiffness to match \"imbalanced\" biomechanical properties of the concave and convex paravertebral muscles, respectively, and treat EOS by applying the block-structure brace.A 3d CAD draft model of the brace contour was implemented from 3D scanning. The asymmetric stiffness block-structure brace was designed in Rhinoceros and the Finite Ele-ment (FE) model was imported into ABAQUS. FE simulation was employed to study the mechanical characteristics of the brace, which provided a quan-titative index for the \"imbalanced\" property of brace stiffness. The results of the FE simulation showed that the stiffnesses of the concave and convex sides were 145.88 N/mm and 35.95 N/mm, respectively. The block-structure brace was fabricated using 3d printing. Asymmetric stiffness was evaluated by corrective force measurements, which were obtained from a thin-film pressure sensor equipped on the brace. The patient-specific asymmetric stiffness brace was applied to clinical practice in a one-year old EOS patient. A novel low-cost 3D printed brace design method for EOS was proposed in this study that could potentially be useful in patient treatment acceptance.","PeriodicalId":49305,"journal":{"name":"Journal of Medical Devices-Transactions of the Asme","volume":null,"pages":null},"PeriodicalIF":0.9,"publicationDate":"2022-07-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49221053","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Design, Improvement and Evaluation of a Novel in Situ Implanted Bionic Artificial Anal Sphincter 一种新型原位植入仿生人工肛门括约肌的设计、改进与评价
IF 0.9 4区 医学
Journal of Medical Devices-Transactions of the Asme Pub Date : 2022-07-15 DOI: 10.1115/1.4055001
Lichao Wang, G. Yan, Ding Han, Dasheng Liu, Fangfang Hua, Tong Wu
{"title":"Design, Improvement and Evaluation of a Novel in Situ Implanted Bionic Artificial Anal Sphincter","authors":"Lichao Wang, G. Yan, Ding Han, Dasheng Liu, Fangfang Hua, Tong Wu","doi":"10.1115/1.4055001","DOIUrl":"https://doi.org/10.1115/1.4055001","url":null,"abstract":"\u0000 Artificial anal sphincter has gradually become an emerging means of treating anal incontinence. However, most of the systems cannot be implanted in the human body for a long time due to insufficient reliability. Therefore, this paper has designed and improved a novel bionic artificial anal sphincter (BAAS). In order to make it work reliably for a long time, we first optimized and improved key parts to increase their strength. Given the humid working environment in the body, we optimized the design of the waterproof pressure sensor and carried out experimental research on the sealing of the circuit board and the overall sealing. When evaluating the improved system, I used simulation to analyze the structural strength and motion characteristics of the BAAS and used underwater experiments to simulate the human environment to evaluate the waterproofness of the system. The results showed that the strength of the key joint increased by 49.4%, the average clamping time and opening time of the prosthesis were 14.5s and 13.4s, respectively, and the angular velocity of the pendulum rod approaching the intestine was about 4.5°/s, which was in line with the normal defecation process of the human body. The performance is stable and reliable in the 20-day underwater body fluid simulation experiment. BAAS basically meets the application needs of long-term implantation in the treatment of fecal incontinence.","PeriodicalId":49305,"journal":{"name":"Journal of Medical Devices-Transactions of the Asme","volume":null,"pages":null},"PeriodicalIF":0.9,"publicationDate":"2022-07-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48436624","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Comparison of Temperature Equilibrium Rate and Cell Growth/Viability Under Air Circulation in Cryogenic Storage Container 低温贮藏容器空气循环条件下温度平衡率与细胞生长/活力的比较
IF 0.9 4区 医学
Journal of Medical Devices-Transactions of the Asme Pub Date : 2022-06-17 DOI: 10.1115/1.4054833
Jeong-Yeon Park, Dong-won Lee, Sunray Lee, Dong-Mok Lee, Jienny Lee, Hyun-sook Park, G. Yoon
{"title":"Comparison of Temperature Equilibrium Rate and Cell Growth/Viability Under Air Circulation in Cryogenic Storage Container","authors":"Jeong-Yeon Park, Dong-won Lee, Sunray Lee, Dong-Mok Lee, Jienny Lee, Hyun-sook Park, G. Yoon","doi":"10.1115/1.4054833","DOIUrl":"https://doi.org/10.1115/1.4054833","url":null,"abstract":"\u0000 With advances in biotechnology, the field of cryopreservation has been continuously developed and improved. Typical cryo-container was designed with minimal flow to avoid possible structural defects in LN2 tank, which has a higher thermal conductivity than vapor nitrogen tank. If cells are placed in typical cryo-container and stored in VN2 tank, cross-contamination can be prevented, but the cell viability after thawing may be reduced. The structure of typical cryo-containers are not optimized for vaporized nitrogen to flow quickly into the container and its circulation well. Therefore, we proposed new cryo-container models that can maintain mechanical strength while optimizing the fluid flow structure, and performed thermal-structural coupled field analysis on cryo-containers. We confirmed the cryo-containers by comparing the equivalent stress distributions formed around through holes and evaluating thermal equilibrium in the cryogenic steady state through flow analysis. Prototype cryo-containers and typical cryo-containers were placed in VN2 tank for a period of time to observe temperature changes. As a result, the time it takes to reach the temperature equilibrium has been reduced to 55% level compared with the typical cryo-containers. Additionally, C2C12 and hADMSC cells were checked after storage under two temperature conditions (-80 and -196°C). In both cell, viability, adhesion and relative cell proliferation were improved by up to 15-20% in new containers compared to typical products. The developed container is expected to maintain stability well by being applied to storage and transportation of advanced medicines that require cryopreservation.","PeriodicalId":49305,"journal":{"name":"Journal of Medical Devices-Transactions of the Asme","volume":null,"pages":null},"PeriodicalIF":0.9,"publicationDate":"2022-06-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48316877","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A Modular MRI-Compatible Pipette Simulator to Evaluate How Design Effects the Basilar Thumb Joint Mechanics 模块化MRI兼容移液管模拟器评估设计对拇指基底关节力学的影响
IF 0.9 4区 医学
Journal of Medical Devices-Transactions of the Asme Pub Date : 2022-06-03 DOI: 10.1115/1.4054725
Nolan M. Norton, K. Fischer
{"title":"A Modular MRI-Compatible Pipette Simulator to Evaluate How Design Effects the Basilar Thumb Joint Mechanics","authors":"Nolan M. Norton, K. Fischer","doi":"10.1115/1.4054725","DOIUrl":"https://doi.org/10.1115/1.4054725","url":null,"abstract":"\u0000 People who frequently use micropipettes experience hand and upper limb disorders. The basilar thumb joint, also known as the first carpometacarpal or trapeziometacarpal joint, is commonly affected by osteoarthritis (OA). Mechanical factors are associated with OA initiation and progression. We developed a MRI-compatible modular micropipette simulator to improve understanding of how micropipette design affects basilar thumb joint contact mechanics. The micropipette simulator also addresses limitations of current techniques for studying pipetting and basilar thumb joint mechanics. Its modularity will allow future studies to examine handle design parameters such as handle diameter, cross-sectional shape, and other features. A micropipette simulator with a cylindrical handle (length 127 mm, diameter 25 mm) was used with one subject to demonstrate the system's feasibility. Contact areas were within the range of prior data from basilar thumb joint models in power grasp and lateral pinch, and contact pressures were the same order of magnitude.","PeriodicalId":49305,"journal":{"name":"Journal of Medical Devices-Transactions of the Asme","volume":null,"pages":null},"PeriodicalIF":0.9,"publicationDate":"2022-06-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45523638","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
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