Nature Reviews Neuroscience最新文献_第6页

Safety in numbers 人多安全

IF 28.7 1区医学

Nature Reviews Neuroscience Pub Date : 2024-09-26 DOI: 10.1038/s41583-024-00868-0

Sian Lewis

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The origins of freezing 冷冻的起源

IF 28.7 1区医学

Nature Reviews Neuroscience Pub Date : 2024-09-10 DOI: 10.1038/s41583-024-00857-3

Philip Tovote

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Neural control of gut regulatory T cells 肠道调节性 T 细胞的神经控制

IF 28.7 1区医学

Nature Reviews Neuroscience Pub Date : 2024-09-03 DOI: 10.1038/s41583-024-00863-5

Darran Yates

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Astrocyte antennae 星形胶质细胞触角

IF 28.7 1区医学

Nature Reviews Neuroscience Pub Date : 2024-09-03 DOI: 10.1038/s41583-024-00864-4

Sian Lewis

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Mapping future locations 绘制未来地点图。

IF 28.7 1区医学

Nature Reviews Neuroscience Pub Date : 2024-09-02 DOI: 10.1038/s41583-024-00861-7

Katherine Whalley

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Disentangling human inference 解构人类推理

IF 28.7 1区医学

Nature Reviews Neuroscience Pub Date : 2024-09-02 DOI: 10.1038/s41583-024-00860-8

Jake Rogers

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Thyroid hormone modulates exploration circuits 甲状腺激素调节探索回路

IF 28.7 1区医学

Nature Reviews Neuroscience Pub Date : 2024-09-02 DOI: 10.1038/s41583-024-00862-6

Katherine Whalley

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Advances in the labelling and selective manipulation of synapses 突触标记和选择性操作的进展。

IF 28.7 1区医学

Nature Reviews Neuroscience Pub Date : 2024-08-22 DOI: 10.1038/s41583-024-00851-9

Binod Timalsina, Sangkyu Lee, Bong-Kiun Kaang

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引用次数: 0

Neuronal maturation and axon regeneration: unfixing circuitry to enable repair 神经元成熟与轴突再生：解除电路固定以实现修复

IF 28.7 1区医学

Nature Reviews Neuroscience Pub Date : 2024-08-20 DOI: 10.1038/s41583-024-00849-3

Brett J. Hilton, Jarred M. Griffin, James W. Fawcett, Frank Bradke

{"title":"Neuronal maturation and axon regeneration: unfixing circuitry to enable repair","authors":"Brett J. Hilton, Jarred M. Griffin, James W. Fawcett, Frank Bradke","doi":"10.1038/s41583-024-00849-3","DOIUrl":"10.1038/s41583-024-00849-3","url":null,"abstract":"Mammalian neurons lose the ability to regenerate their central nervous system axons as they mature during embryonic or early postnatal development. Neuronal maturation requires a transformation from a situation in which neuronal components grow and assemble to one in which these components are fixed and involved in the machinery for effective information transmission and computation. To regenerate after injury, neurons need to overcome this fixed state to reactivate their growth programme. A variety of intracellular processes involved in initiating or sustaining neuronal maturation, including the regulation of gene expression, cytoskeletal restructuring and shifts in intracellular trafficking, have been shown to prevent axon regeneration. Understanding these processes will contribute to the identification of targets to promote repair after injury or disease. During their maturation, mammalian neurons lose the capacity to regrow their axons after an injury. Here, Hilton et al. explore the neuron maturation processes that limit axon regeneration, including changes in gene expression, cytoskeletal dynamics, and intracellular signalling and trafficking.","PeriodicalId":49142,"journal":{"name":"Nature Reviews Neuroscience","volume":"25 10","pages":"649-667"},"PeriodicalIF":28.7,"publicationDate":"2024-08-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142007531","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

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Reply to ‘The language network is topographically diverse and driven by rapid syntactic inferences’ 回复 "语言网络具有拓扑多样性，由快速句法推断驱动"。

IF 28.7 1区医学

Nature Reviews Neuroscience Pub Date : 2024-08-09 DOI: 10.1038/s41583-024-00853-7

Evelina Fedorenko, Anna A. Ivanova, Tamar I. Regev

引用次数: 0