{"title":"Twenty-five years of covering neuroscience","authors":"","doi":"10.1038/s41583-025-00966-7","DOIUrl":"10.1038/s41583-025-00966-7","url":null,"abstract":"In this issue, we mark the 25th anniversary of Nature Reviews Neuroscience.","PeriodicalId":49142,"journal":{"name":"Nature Reviews Neuroscience","volume":"26 10","pages":"571-571"},"PeriodicalIF":26.7,"publicationDate":"2025-09-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.nature.comhttps://www.nature.com/articles/s41583-025-00966-7.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145086644","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The unexpected value of communicating science to the public","authors":"Nicole C. Rust","doi":"10.1038/s41583-025-00968-5","DOIUrl":"10.1038/s41583-025-00968-5","url":null,"abstract":"As a group, our scientific community has a responsibility to unpack the ‘what’ and ‘why’ behind our work for the public, not least because much of our research is publicly funded. Here, I argue that alongside this important service, there are less apparent and perhaps even more motivating reasons to engage in science communication. I also offer some tips on getting started.","PeriodicalId":49142,"journal":{"name":"Nature Reviews Neuroscience","volume":"26 10","pages":"572-573"},"PeriodicalIF":26.7,"publicationDate":"2025-08-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144905921","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Rethinking women’s brain health","authors":"Julia Sacher, Ingo Bechmann","doi":"10.1038/s41583-025-00969-4","DOIUrl":"10.1038/s41583-025-00969-4","url":null,"abstract":"Far from being a niche concern, women’s brain health is a global issue, affecting more than half of the world’s population. Despite this, the unique aspects of how the female brain adapts, reorganizes and ages, particularly those shaped by hormonal transitions across the lifespan, have not received proportionate attention in research agendas, funding priorities or clinical guidelines.","PeriodicalId":49142,"journal":{"name":"Nature Reviews Neuroscience","volume":"26 10","pages":"576-578"},"PeriodicalIF":26.7,"publicationDate":"2025-08-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144905927","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Working together to build strong scientific communities","authors":"Megan R. Carey","doi":"10.1038/s41583-025-00967-6","DOIUrl":"10.1038/s41583-025-00967-6","url":null,"abstract":"The scientific enterprise depends on attracting and retaining the very best talent, yet barriers persist that perpetuate inequities in the scientific workforce. Here I discuss the efforts of the ALBA Network to help anyone to work effectively to maximize scientific progress by making their communities more equitable and inclusive.","PeriodicalId":49142,"journal":{"name":"Nature Reviews Neuroscience","volume":"26 10","pages":"574-575"},"PeriodicalIF":26.7,"publicationDate":"2025-08-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144900467","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Theoretical neuroscience has room to grow","authors":"Ann Kennedy","doi":"10.1038/s41583-025-00965-8","DOIUrl":"10.1038/s41583-025-00965-8","url":null,"abstract":"The goal of theoretical neuroscience is to uncover principles of neural computation through careful design and interpretation of mathematical models. Here, I examine the use of top-down conceptual and bottom-up mechanistic models in theoretical neuroscience, exploring how they connect with experimental practice and where there is room for future growth.","PeriodicalId":49142,"journal":{"name":"Nature Reviews Neuroscience","volume":"26 10","pages":"585-586"},"PeriodicalIF":26.7,"publicationDate":"2025-08-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144900471","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Brain on standby — how torpor made ‘tauopathy’ reversible","authors":"Nina M. Rzechorzek","doi":"10.1038/s41583-025-00964-9","DOIUrl":"10.1038/s41583-025-00964-9","url":null,"abstract":"In this Journal Club, Nina Rzechorzek explores a 2003 article showing that, during hibernation, ground squirrels reversibly accumulate highly phosphorylated tau in the brain (a hallmark of Alzheimer’s disease) without developing neurofibrillary tangle pathology.","PeriodicalId":49142,"journal":{"name":"Nature Reviews Neuroscience","volume":"26 10","pages":"590-590"},"PeriodicalIF":26.7,"publicationDate":"2025-08-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144900480","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Time to let the model speak for itself with closed-loop neurophysiology","authors":"Benjamin R. Cowley","doi":"10.1038/s41583-025-00962-x","DOIUrl":"10.1038/s41583-025-00962-x","url":null,"abstract":"In this Journal Club, Benjamin Cowley discusses a 2009 tour-de-force that provided a recipe for constructing closed-loop algorithms by letting predictive models speak for themselves.","PeriodicalId":49142,"journal":{"name":"Nature Reviews Neuroscience","volume":"26 10","pages":"589-589"},"PeriodicalIF":26.7,"publicationDate":"2025-08-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144883305","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Synaptic connectomics: status and prospects","authors":"Davi D. Bock","doi":"10.1038/s41583-025-00957-8","DOIUrl":"10.1038/s41583-025-00957-8","url":null,"abstract":"High-throughput volume electron microscopy and deep learning-driven automated segmentation have revolutionized the mapping of neural circuits at the level of individual neurons and synapses, revealing new cell types and unexpected network architectures in diverse species. Although prospects for continued progress in connectomics are excellent, substantial technical and conceptual hurdles remain.","PeriodicalId":49142,"journal":{"name":"Nature Reviews Neuroscience","volume":"26 10","pages":"581-582"},"PeriodicalIF":26.7,"publicationDate":"2025-08-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144840310","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"CRISPR-TO: a versatile tool for programmable control of the spatial transcriptome","authors":"Mengting Han","doi":"10.1038/s41583-025-00958-7","DOIUrl":"10.1038/s41583-025-00958-7","url":null,"abstract":"In this Tools of the Trade article, Mengting Han discusses the development of CRISPR-TO, a programmable method for perturbing endogenous RNA localization, and its use for functional screening of the spatial transcriptome in neurons.","PeriodicalId":49142,"journal":{"name":"Nature Reviews Neuroscience","volume":"26 10","pages":"587-587"},"PeriodicalIF":26.7,"publicationDate":"2025-08-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144819147","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The emergence of NeuroAI: bridging neuroscience and artificial intelligence","authors":"Sadra Sadeh, Claudia Clopath","doi":"10.1038/s41583-025-00954-x","DOIUrl":"10.1038/s41583-025-00954-x","url":null,"abstract":"Neuroscience has inspired artificial intelligence (AI) for decades but, in recent years, AI tools have begun to revolutionize neuroscience research. The emerging field of NeuroAI has the potential to transform large-scale neural modelling and data-driven neuroscience discovery. The field must balance exploiting AI’s power while maintaining interpretability and biological insight.","PeriodicalId":49142,"journal":{"name":"Nature Reviews Neuroscience","volume":"26 10","pages":"583-584"},"PeriodicalIF":26.7,"publicationDate":"2025-08-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144796965","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}