Danielle Machado Farias, Anne Evelyn Oliveira Moura, Eduardo Eudes Nóbrega de Araújo, Amanda Almeida Leite, Mirela Godoi Nunes de Oliveira, Vinícius Belém Rodrigues, Elaine Judite de Amorim Carvalho
{"title":"Cementoblastomas: a report of 2 cases","authors":"Danielle Machado Farias, Anne Evelyn Oliveira Moura, Eduardo Eudes Nóbrega de Araújo, Amanda Almeida Leite, Mirela Godoi Nunes de Oliveira, Vinícius Belém Rodrigues, Elaine Judite de Amorim Carvalho","doi":"10.1016/j.oooo.2025.01.070","DOIUrl":"10.1016/j.oooo.2025.01.070","url":null,"abstract":"<div><div>This report describes 2 cases of cementoblastoma in patients with distinct ages, an adolescent, and elderly. A 17-year-old female presented with a painful swelling in the posterior mandible. Computed tomography revealed a hyperdense and well-delimited lesion, surrounded a hypodense halo, associated with the root of the right mandibular first molar. The second case refers to a 61-year-old female who presented with a painless lesion identified in a routine radiographic examination. The imaging features were similar to the first case. The lesion involved the root of the mandibular left first molar. Cementoblastoma was the clinic-radiographic diagnosis in both cases, which were excised with extractions of involved teeth. Macroscopically, masses of calcified tissue fused to the dental roots were observed. Microscopically, trabeculae of cementoid material adhered to the dental roots, cementoblasts, and cementocytes were noted, confirming the diagnosis of cementoblastoma. The patients remain without signs of recurrence after 8 months of treatment.</div></div>","PeriodicalId":49010,"journal":{"name":"Oral Surgery Oral Medicine Oral Pathology Oral Radiology","volume":"139 5","pages":"Page e13"},"PeriodicalIF":2.0,"publicationDate":"2025-03-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143619839","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Liova Amaru Chabot-Diaz, Fabrício Bitu Sousa, Ana Paula Negreiros Nunes Alves, Karuza Maria Alves Pereira, Farah Essguí Orellana Martinez, Alana Lima dos Santos, Mário Rógerio Lima Mota
{"title":"Lymphoepithelial carcinoma at the lingual apex: a case report","authors":"Liova Amaru Chabot-Diaz, Fabrício Bitu Sousa, Ana Paula Negreiros Nunes Alves, Karuza Maria Alves Pereira, Farah Essguí Orellana Martinez, Alana Lima dos Santos, Mário Rógerio Lima Mota","doi":"10.1016/j.oooo.2025.01.051","DOIUrl":"10.1016/j.oooo.2025.01.051","url":null,"abstract":"<div><div>Lymphoepithelial carcinoma (LEC) rarely occurs in the oral cavity, an association with Epstein-Barr virus (EBV) is commonly observed in nasopharyngeal lesions. A biopsy of a lingual apex nodule was sent from an 85-year-old female. Clinically, the lesion was described as oval, sessile, firm, and normochromic. Histopathological analysis showed a malignant neoplasm composed of epidermoid cells isolated or arranged in islands and cords, exhibiting a syncytial appearance. The cells were pleomorphic, with vesiculated nuclei containing acidophilic macronuclei. The stroma was markedly lymphoid with few eosinophils. It penetrated the tumor proliferation, making it difficult to visualize the islands and cords of epidermoid cells. Tumor cells were immunostained for anti-CKPool, anti-EMA, and anti-EBV, suggesting a diagnosis of LEC. The patient was referred to the Head and Neck Service for oncologic treatment. A combination of histopathology and immunohistochemistry is essential for the diagnosis of LEC. Oral lesions may also be associated with EBV.</div></div>","PeriodicalId":49010,"journal":{"name":"Oral Surgery Oral Medicine Oral Pathology Oral Radiology","volume":"139 5","pages":"Page e10"},"PeriodicalIF":2.0,"publicationDate":"2025-03-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143619931","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Thaís Xavier Pereira da Silva, Janete Dias Almeida, Luis Felipe das Chagas e Silva de Carvalho, Monica Ghislaine Oliveria Alves
{"title":"Secondary oral syphilis mimicking aphthous ulceration in an adolescent: a case report","authors":"Thaís Xavier Pereira da Silva, Janete Dias Almeida, Luis Felipe das Chagas e Silva de Carvalho, Monica Ghislaine Oliveria Alves","doi":"10.1016/j.oooo.2025.01.064","DOIUrl":"10.1016/j.oooo.2025.01.064","url":null,"abstract":"<div><div>A 14-year-old female patient presented with complaints of painful ulcers that first appeared on her tongue 2 months prior. The patient reported having used melaleuca, triamcinolone acetonide, and nystatin with no improvement. Clinically, multiple varying-sized well-defined plaques with ulcerated areas were observed. The lesions were primarily located on the lateral border of the tongue bilaterally and the upper and lower lips mucosa. Diagnostic considerations included syphilis, vitamin B12 deficiency, and major aphthous ulcer. Subsequent testing revealed positive results for VDRL and FTA-ABS, confirming the diagnosis of secondary syphilis. The patient was then referred to an infectious disease specialist for treatment. Syphilis poses a significant public health challenge globally, with increasing incidence rates, particularly among younger populations. The diagnosis of syphilis can be complex due to the overlapping of clinical manifestations with other conditions, in addition to the serious issue of self-medication. Careful evaluation is necessary for accurate diagnosis and treatment.</div></div>","PeriodicalId":49010,"journal":{"name":"Oral Surgery Oral Medicine Oral Pathology Oral Radiology","volume":"139 5","pages":"Page e12"},"PeriodicalIF":2.0,"publicationDate":"2025-03-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143619867","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ana Laura Sabino Coelho, Satiro Watanabe, Mário Serra Ferreira, Wilson José Mariano, Eneida Franco Vêncio, Natália Gratão de Oliveira Resende, Maria Alves Garcia Silva
{"title":"Myoepithelial carcinoma ex pleomorphic adenoma of the maxillary sinus: a case report","authors":"Ana Laura Sabino Coelho, Satiro Watanabe, Mário Serra Ferreira, Wilson José Mariano, Eneida Franco Vêncio, Natália Gratão de Oliveira Resende, Maria Alves Garcia Silva","doi":"10.1016/j.oooo.2025.01.053","DOIUrl":"10.1016/j.oooo.2025.01.053","url":null,"abstract":"<div><div>Myoepithelial carcinoma arising from a pleomorphic adenoma is a rare neoplasm of the salivary glands, accounting for 3.6% of salivary gland tumors and 12% of salivary gland malignancies. Here, we present the case of a 58-year-old male patient who presented with swelling of the palate. A prior diagnosis of a “benign tumor” had been established. Oral examination revealed a nodular lesion on the hard palate measuring 4 cm, firm on palpation and partially purplish, with a significant increase noted over the past 4 months. Radiographic imaging demonstrated involvement of the entire maxillary sinus. Histopathological examination revealed dysplastic clear cell nests and dysplastic epithelioid cell cords. Morphological and immunohistochemical analyses confirmed the diagnosis of myoepithelial carcinoma. The patient was referred for treatment with chemotherapy and radiotherapy at the cancer hospital. This case highlights the critical importance of early diagnosis in the management of malignant lesions, as timely intervention significantly impacts patient outcomes.</div></div>","PeriodicalId":49010,"journal":{"name":"Oral Surgery Oral Medicine Oral Pathology Oral Radiology","volume":"139 5","pages":"Page e10"},"PeriodicalIF":2.0,"publicationDate":"2025-03-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143619933","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Alice Souza Villar Cassimiro Fonseca, Luciana Munhoz, Plauto Christopher Aranha Watanabe, Emiko Saito Arita, Núbia Rafaelle Oliveira de Meneses, Lucila Massu Yoshizaki Akinaga Moreira, Claudio Costa
{"title":"Oral manifestations of proteus syndrome: case report","authors":"Alice Souza Villar Cassimiro Fonseca, Luciana Munhoz, Plauto Christopher Aranha Watanabe, Emiko Saito Arita, Núbia Rafaelle Oliveira de Meneses, Lucila Massu Yoshizaki Akinaga Moreira, Claudio Costa","doi":"10.1016/j.oooo.2025.01.040","DOIUrl":"10.1016/j.oooo.2025.01.040","url":null,"abstract":"<div><div>Proteus Syndrome is a rare, congenital, and nonhereditary disorder, caused by a mutation in the AKT1 gene and with a highly variable phenotype. This condition is characterized by exacerbated, heterogeneous, and progressive growth of multiple tissues, notably bone, causing alterations and asymmetries in the oral and maxillofacial region. Caucasian 32-year-old man came to the dental service complaining of painful symptoms when chewing and generalized gingival inflammation. The extraoral and intraoral clinical examination revealed significant facial asymmetry, limited mouth opening, and unilateral macroglossia. The panoramic radiograph showed bimaxillary asymmetry, bone involvement in a mosaic pattern, midline displacement, and changes in tooth eruption and maturation, and the occlusal radiograph showed images suggesting exostoses or multiple osteomas. A planigraphy of the temporomandibular joint showed a disproportionate increase in the mandibular structures on the left. According to the clinical and imaging findings, the diagnosis of Proteus Syndrome was reached, and periodic follow-up was indicated.</div></div>","PeriodicalId":49010,"journal":{"name":"Oral Surgery Oral Medicine Oral Pathology Oral Radiology","volume":"139 5","pages":"Page e7"},"PeriodicalIF":2.0,"publicationDate":"2025-03-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143619994","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Júlia Narcizo Cardoso, Melka Coêlho Sá, Antônio Carlos Marqueti, Rosany Larissa Brito de Oliveira, Sara Juliana de Abreu de Vasconcellos, Sueli Aguiar Pereira Araújo, Álvaro Bezerra Cardoso
{"title":"Ossifying fibroma involving maxillary sinus: a case report","authors":"Júlia Narcizo Cardoso, Melka Coêlho Sá, Antônio Carlos Marqueti, Rosany Larissa Brito de Oliveira, Sara Juliana de Abreu de Vasconcellos, Sueli Aguiar Pereira Araújo, Álvaro Bezerra Cardoso","doi":"10.1016/j.oooo.2025.01.045","DOIUrl":"10.1016/j.oooo.2025.01.045","url":null,"abstract":"<div><div>A 13-year-old male patient was referred to the Oral and Maxillofacial Surgery Department due to edema on the right hemiface. During clinical examination, extraorally he presented a volume increase in the paranasal region and, intraorally, bulging of the bottom of the vestibule of the maxilla, with a firm consistency, normal color, and painless on palpation. On imaging examination, a radiopaque lesion was identified in the region of the alveolar bone extending to the maxillary sinus, with limits on the orbital floor and lateral nasal wall. After incisional biopsy, the lesion was excised under general anesthesia. The specimen was submitted to a histopathological study, revealing fibrous connective tissue, trabeculated bone tissue, and fragments of respiratory mucosa, compatible with Ossifying Fibroma. In the 2-year postoperative period, bone repair was observed within normal limits, without signs of recurrence or volume increase in the operated region. The patient presented without complaints or painful symptoms.</div></div>","PeriodicalId":49010,"journal":{"name":"Oral Surgery Oral Medicine Oral Pathology Oral Radiology","volume":"139 5","pages":"Pages e8-e9"},"PeriodicalIF":2.0,"publicationDate":"2025-03-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143620008","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Beatriz Bastos Macêdo, Liciane Mariano dos Santos Menezes, Maria Eduarda Haerdy Monteiro, Edval Reginaldo Tenório Júnios, Viviane Almeida Sarmento, Patrícia Miranda Leite Ribeiro, Liliane Lins-Kusterer
{"title":"Aspergillosis in an immunocompromised patient with acute myelomonocytic leukemia","authors":"Beatriz Bastos Macêdo, Liciane Mariano dos Santos Menezes, Maria Eduarda Haerdy Monteiro, Edval Reginaldo Tenório Júnios, Viviane Almeida Sarmento, Patrícia Miranda Leite Ribeiro, Liliane Lins-Kusterer","doi":"10.1016/j.oooo.2025.01.077","DOIUrl":"10.1016/j.oooo.2025.01.077","url":null,"abstract":"<div><div>Aspergillosis is an opportunistic fungal disease that manifests in immunocompromised individuals and has a high associated mortality. A 33-year-old male patient diagnosed with acute myelomonocytic leukemia during hospitalization started chemotherapy and at D20 of the patient cycle evolved with a black lesion in the hard palate, associated with facial edema, perforation in the palate and severe dental mobility in the maxilla. Biopsy and culture of the removed fragments were performed. The histopathological report of the collected fragments included findings of hyphae suggestive of aspergillosis. The patient reported nosebleeds and rhinorrhea, in addition to hearing loss, and is being monitored with voriconazole medication and is preparing for surgery and a new cycle of chemotherapy. The case demonstrates the importance of clinical follow-up of patients undergoing cancer treatment for early diagnosis of infectious advents.</div></div>","PeriodicalId":49010,"journal":{"name":"Oral Surgery Oral Medicine Oral Pathology Oral Radiology","volume":"139 5","pages":"Page e15"},"PeriodicalIF":2.0,"publicationDate":"2025-03-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143620822","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Camille Schipper Schwartz, Karoline Ferreira Farias Catarino, Marcelo Rodrigues Camargos, Eduarda Almeida Borges de Araújo, Fabio Ramoa Pires, Caroline Lopes Paiva, Aguida Maria Menezes Aguiar Miranda
{"title":"Periosteal osteoma in the coronoid process: a case report","authors":"Camille Schipper Schwartz, Karoline Ferreira Farias Catarino, Marcelo Rodrigues Camargos, Eduarda Almeida Borges de Araújo, Fabio Ramoa Pires, Caroline Lopes Paiva, Aguida Maria Menezes Aguiar Miranda","doi":"10.1016/j.oooo.2025.01.050","DOIUrl":"10.1016/j.oooo.2025.01.050","url":null,"abstract":"<div><div>Osteomas are benign neoplasms composed of compact or cancellous bone. They are rarely diagnosed outside the craniofacial skeleton. They can arise on the surface of the bone (periosteal, peripheral, or exophytic osteoma) or in the medullary bone (endosteal or central osteoma). A 52-year-old female patient presented with an increase in hard volume in the left preauricular region and a sclerotic mass circumscribed in the region of the left coronoid process on a panoramic radiograph. Computed tomography revealed a lobulated hyperdense image, measuring approximately 3 cm in its largest diameter in the left coronoid process. Initially, osteoma was suspected and surgical excision under general anesthesia was proposed. Due to intraoperative complications, part of the lesion was not removed. With histopathological confirmation of osteoma, and without aesthetic or functional impact, clinical and radiographic monitoring was defined by the team together with the patient. She continues without signs of growth of the lesion, monitored for 9 months.</div></div>","PeriodicalId":49010,"journal":{"name":"Oral Surgery Oral Medicine Oral Pathology Oral Radiology","volume":"139 5","pages":"Page e9"},"PeriodicalIF":2.0,"publicationDate":"2025-03-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143620013","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Lara Maria Alencar Ramos Innocentini, Isabella Cristine dos Santos, Ana Carolina Fragoso Motta, Hilton Marcos Alves Hicz, Alan Grupioni Lourenço, Joel Del Bel Padua, Leandro Dorigan de Macedo
{"title":"Epithelioid hemangioendothelioma of the oral cavity: case report","authors":"Lara Maria Alencar Ramos Innocentini, Isabella Cristine dos Santos, Ana Carolina Fragoso Motta, Hilton Marcos Alves Hicz, Alan Grupioni Lourenço, Joel Del Bel Padua, Leandro Dorigan de Macedo","doi":"10.1016/j.oooo.2025.01.027","DOIUrl":"10.1016/j.oooo.2025.01.027","url":null,"abstract":"<div><div>A 49-year-old female was referred to a stomatologist due to complaints of enlargement and pain associated with a vascular lesion that had been monitored for 2 years. Her medical history revealed no systemic diseases. During the intraoral examination, a blue-purplish nodule was observed on the oral mucosa of the right lower lip and exhibited a fibrous region upon palpation with 1.0 cm in its greatest dimension. An incisional biopsy was performed, and histopathological examination revealed the presence of cords or nests of polygonal to slightly spindled epithelioid cells, with the formation of intracytoplasmic lumina, surrounding small vessels with perineural infiltration. Immunohistochemistry markers were positive for CD34, CD31, factor VIII-related antigen (FVIIIRAg), FLI1, D2-40, and ERG, confirming the diagnosis of epithelioid hemangioendothelioma (EHE). The patient was referred to a head and neck surgeon for complete removal of the EHE. She has been under observation for 2 years with no signs of recurrence.</div></div>","PeriodicalId":49010,"journal":{"name":"Oral Surgery Oral Medicine Oral Pathology Oral Radiology","volume":"139 5","pages":"Page e5"},"PeriodicalIF":2.0,"publicationDate":"2025-03-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143620128","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Fernanda Luiza Araújo de Lima Castro, Henrique Bemfica de Faria Freitas, Sérgio Antonucci Amaral, Renata Gonçalves Resende, Maria Cássia Ferreira Aguiar, Patrícia Carlos Caldeira, Júlio César Tanos Lacerda
{"title":"Surgical excision of large myoepithelioma in the palate","authors":"Fernanda Luiza Araújo de Lima Castro, Henrique Bemfica de Faria Freitas, Sérgio Antonucci Amaral, Renata Gonçalves Resende, Maria Cássia Ferreira Aguiar, Patrícia Carlos Caldeira, Júlio César Tanos Lacerda","doi":"10.1016/j.oooo.2025.01.032","DOIUrl":"10.1016/j.oooo.2025.01.032","url":null,"abstract":"<div><div>A 30-year-old female presented to the hospital with an extensive tumoral lesion on the palate, with an evolution of 20 years, causing dysphagia and difficulty in speaking. Incisional biopsy revealed a fragment of nonencapsulated neoplasm with proliferation of myoepithelial cells, forming cellular cords. The cells had large and eosinophilic cytoplasm and rounded nuclei displaced to the periphery, configuring a plasmacytoid morphology. The stroma of the lesion was composed of fibrous connective tissue, sometimes with a myxomatous appearance. The diagnosis was compatible with myoepithelioma. She was submitted to surgery under general anesthesia for conservative surgical enucleation of the lesion. To cover the raw area, a double-layer acellular dermal matrix was used, composed of bovine collagen internally and silicone externally, which was removed 3 weeks after surgery. After removal, a granulation tissue was observed, later giving way to the epithelial tissue of the palate. The patient is on regular follow-up with no abnormalities.</div></div>","PeriodicalId":49010,"journal":{"name":"Oral Surgery Oral Medicine Oral Pathology Oral Radiology","volume":"139 5","pages":"Page e6"},"PeriodicalIF":2.0,"publicationDate":"2025-03-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143620135","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}