{"title":"Deep learning for automated alveolar cleft segmentation and bone graft volume estimation in cone-beam computed tomography imaging: a multicenter study","authors":"António Vicente DDS, Msc , Kuo Feng Hung DDS, MDS, PhD , Zineng Xu Msc , Jiegang Yang DDS, PhD , Jian Li MD, PhD , Anna-Paulina Wiedel DDS, PhD , Magnus Becker MD, PhD , Susanne Brogårdh-Roth DDS, PhD , Peng Ding PhD , Kristina Hellén-Halme DDS, PhD , Xie-Qi Shi DDS, PhD","doi":"10.1016/j.oooo.2025.10.020","DOIUrl":"10.1016/j.oooo.2025.10.020","url":null,"abstract":"<div><h3>Objective</h3><div>To train and validate a deep learning-based diagnostic tool capable of accurately segmenting the alveolar cleft region and automatically estimating the required bone graft volume using cone-beam computed tomography (CBCT) imaging.</div></div><div><h3>Study Design</h3><div>Eighty-eight CBCT scans from patients with nonsyndromic unilateral clefts were divided into training (n = 45), validation (n = 10), and test (n = 33) sets. Two annotators performed manual segmentations, and the intersection of these served as the ground truth for training three-dimensional (3D) U-Net models. The dice similarity coefficient (DSC) was calculated to validate the tool by comparing manual and automated segmentations. Three observers evaluated the resulting deep learning model using 33 CBCT scans and performing subjective assessments in terms of shape and size.</div></div><div><h3>Results</h3><div>The dice similarity coefficient (DSC) between the two annotators was 0.66, and between the automated and manual segmentations, 0.78. The observers considered the automated segmentations acceptable in 82%-94% of the cases. The deep learning-based tool took approximately second seconds to perform an automated segmentation, while manual segmentation by the annotators required 14 and 6.5 minutes.</div></div><div><h3>Conclusion</h3><div>The deep learning-based tool that was developed in the present study can accurately perform automated segmentations of unilateral alveolar clefts and estimate the required bone graft volume.</div></div>","PeriodicalId":49010,"journal":{"name":"Oral Surgery Oral Medicine Oral Pathology Oral Radiology","volume":"141 3","pages":"Pages 400-408"},"PeriodicalIF":1.9,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145752292","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A surgeon with a fork, in a world of soup","authors":"Ömer Uranbey DDS, PhD","doi":"10.1016/j.oooo.2025.07.020","DOIUrl":"10.1016/j.oooo.2025.07.020","url":null,"abstract":"","PeriodicalId":49010,"journal":{"name":"Oral Surgery Oral Medicine Oral Pathology Oral Radiology","volume":"141 3","pages":"Pages 418-419"},"PeriodicalIF":1.9,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145758110","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Lauren Anderson DMD , Janice Weinberg ScD , Charles Henry DDS , Pushkar Mehra DMD, MS, FACS
{"title":"Perception of advanced practice providers in academic oral and maxillofacial surgery","authors":"Lauren Anderson DMD , Janice Weinberg ScD , Charles Henry DDS , Pushkar Mehra DMD, MS, FACS","doi":"10.1016/j.oooo.2025.07.017","DOIUrl":"10.1016/j.oooo.2025.07.017","url":null,"abstract":"<div><h3>Objective</h3><div>The objective of this study was to assess differences in the perception of the role of advanced practice providers (APPs) within an academic oral and maxillofacial surgery (OMS) department.</div></div><div><h3>Study Design</h3><div>We surveyed OMS providers including APPs, residents, and attending surgeons. The survey covered 5 areas: impact of APPs on resident training, knowledge of APP training, interaction with APPs, scope-of-practice of APPs, and role of APPs in the health care team.</div></div><div><h3>Results</h3><div>The attendings and APPs felt that the APPs had a positive impact on resident education, although the residents disagreed. Attendings and residents had limited knowledge about the APP training background. There was general agreement in the APP scope-of-practice, excepting for procedures. Attendings and the APPs felt that the role of the APP was well defined, although the residents disagreed.</div></div><div><h3>Conclusions</h3><div>As the role of APPs within academic OMS continues to evolve, it is important to address the differences in the perception of APPs among providers. (Oral Surg Oral Med Oral Pathol Oral Radiol YEAR;VOL:page range)</div></div>","PeriodicalId":49010,"journal":{"name":"Oral Surgery Oral Medicine Oral Pathology Oral Radiology","volume":"141 3","pages":"Pages 292-298"},"PeriodicalIF":1.9,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145034405","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"In Memory: Donald M. Cohen, DMD MS MBA (1947 – 2025)","authors":"","doi":"10.1016/j.oooo.2025.11.001","DOIUrl":"10.1016/j.oooo.2025.11.001","url":null,"abstract":"","PeriodicalId":49010,"journal":{"name":"Oral Surgery Oral Medicine Oral Pathology Oral Radiology","volume":"141 3","pages":"Pages 425-426"},"PeriodicalIF":1.9,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146039677","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pushkar Mehra DMD, MS, FACS , David B. Powers DMD, MD, FRCS, FACS , Deepak Kademani DMD, MD, FACS , Paul S. Tiwana DDS, MD, FACS
{"title":"Perspective on trends in oral and maxillofacial surgery residency training and recent match results","authors":"Pushkar Mehra DMD, MS, FACS , David B. Powers DMD, MD, FRCS, FACS , Deepak Kademani DMD, MD, FACS , Paul S. Tiwana DDS, MD, FACS","doi":"10.1016/j.oooo.2025.09.015","DOIUrl":"10.1016/j.oooo.2025.09.015","url":null,"abstract":"<div><div>Oral and Maxillofacial Surgery (OMS) residency programs in the United States have recently experienced a notable decline in match rates. While it may be challenging to identify the root cause of this change, similar experiences in other specialties have identified contributing factors such as the increase in the number of residency positions, changes in specialty perception and workforce needs as contributing factors. This article examines the current state of OMS residency training and provides recommendations aimed to attract more people to the field, take a deeper dive into understanding of the factors contributing to changes in the specialty, and the development of evidence-based interventions.</div></div>","PeriodicalId":49010,"journal":{"name":"Oral Surgery Oral Medicine Oral Pathology Oral Radiology","volume":"141 3","pages":"Pages 299-305"},"PeriodicalIF":1.9,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145477255","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Michael Glick DMD, Alonso Carrasco-Labra DDS, MSc, PhD
{"title":"Reply to Letter to Editor: Probabilistic diagnostic thresholds","authors":"Michael Glick DMD, Alonso Carrasco-Labra DDS, MSc, PhD","doi":"10.1016/j.oooo.2025.10.024","DOIUrl":"10.1016/j.oooo.2025.10.024","url":null,"abstract":"","PeriodicalId":49010,"journal":{"name":"Oral Surgery Oral Medicine Oral Pathology Oral Radiology","volume":"141 3","pages":"Pages 423-424"},"PeriodicalIF":1.9,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145821849","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Wenxue Huang , Menglong Hu , Ye Zhang , Yan Han , Jianxia Hou
{"title":"Tumor potential biomarker: ferritin heavy chain promotes proliferation and migration of oral squamous cell carcinoma","authors":"Wenxue Huang , Menglong Hu , Ye Zhang , Yan Han , Jianxia Hou","doi":"10.1016/j.oooo.2025.09.012","DOIUrl":"10.1016/j.oooo.2025.09.012","url":null,"abstract":"<div><h3>Objective</h3><div>Oral squamous cell carcinoma (OSCC) is one of common malignancy. Ferritin heavy chain (FTH), plays a crucial role in iron homeostasis and regulates cell proliferation. The aims of this study are to investigate the functions of FTH in the progression of OSCC.</div></div><div><h3>Study Design</h3><div>This study included twenty OSCC tissues and adjacent non-tumor tissue samples collected from patients who were pathologically diagnosed with OSCC. We detected expression of FTH gene by qRT-PCR. Meanwhile, expression of marker Ki67, cytokeratin, EGFR, P53, P63, and P40 were detected by immunohistochemistry. Cell proliferation assay, wound healing assay, qPCR and western blot were measured after knockdown of the FTH by small interfering RNAs.</div></div><div><h3>Results</h3><div>Data from the investigation showed that FTH was highly expressed in OSCC tissues. The location of the expression is proliferating epithelial cells, correlated well with the location of Ki67 and P63. Knockdown of FTH inhibited proliferation, migration and invasion of SCC15 and CAL27 cell lines. Adhesion molecules including E-Cadherin, Claudin 1, and Collagen were up-regulation after knockdown of FTH.</div></div><div><h3>Conclusion</h3><div>FTH is overexpressed in OSCC tissues and promotes tumor cell proliferation and invasion. It may be a novel biomarker and therapeutic target in prognosis and treatment of patients with OSCC.</div></div>","PeriodicalId":49010,"journal":{"name":"Oral Surgery Oral Medicine Oral Pathology Oral Radiology","volume":"141 3","pages":"Pages 357-366"},"PeriodicalIF":1.9,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145259477","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Reply to Letter to the Editor “A surgeon with a fork, in a world of soup”","authors":"Pooja Gangwani DDS, MPH, FACD","doi":"10.1016/j.oooo.2025.10.019","DOIUrl":"10.1016/j.oooo.2025.10.019","url":null,"abstract":"","PeriodicalId":49010,"journal":{"name":"Oral Surgery Oral Medicine Oral Pathology Oral Radiology","volume":"141 3","pages":"Page 420"},"PeriodicalIF":1.9,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145844252","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Sebastião Silvério Sousa-Neto DDS, MSc , Thaís Cerqueira Reis Nakamura BSc , Giovanna Calabrese dos Santos BSc , Daniela Giraldo-Roldan DDS, MSc , Moisés Willian Aparecido Gonçalves DDS, MSc , Cinthia Verónica Bardález López de Cáceres DDS, MSc, PhD , Felipe Paiva Fonseca DDS, MSc, PhD , Victor Hugo Lopes de Oliveira Moreira DDS , Elismauro Francisco Mendonça DDS, MSc, PhD , Manoela Domingues Martins DDS, MSc, PhD , Amanda De Farias Gabriel DDS , Albina Altemani MD, PhD , Fernanda Viviane Mariano DDS, MSc, PhD , Alan Roger Santos-Silva DDS, MSc, PhD , Marcio Ajudarte Lopes DDS, MSc, PhD , Luiz Paulo Kowalski MD, PhD , Anna Luíza Damaceno Araújo DDS, MSc, PhD , Matheus Cardoso Moraes BSc, MSc, PhD , Pablo Agustin Vargas DDS, MSc, PhD, FRCPath
{"title":"Comparative analysis of convolutional neural network models for the histopathological differentiation of acinic cell carcinoma and secretory carcinoma","authors":"Sebastião Silvério Sousa-Neto DDS, MSc , Thaís Cerqueira Reis Nakamura BSc , Giovanna Calabrese dos Santos BSc , Daniela Giraldo-Roldan DDS, MSc , Moisés Willian Aparecido Gonçalves DDS, MSc , Cinthia Verónica Bardález López de Cáceres DDS, MSc, PhD , Felipe Paiva Fonseca DDS, MSc, PhD , Victor Hugo Lopes de Oliveira Moreira DDS , Elismauro Francisco Mendonça DDS, MSc, PhD , Manoela Domingues Martins DDS, MSc, PhD , Amanda De Farias Gabriel DDS , Albina Altemani MD, PhD , Fernanda Viviane Mariano DDS, MSc, PhD , Alan Roger Santos-Silva DDS, MSc, PhD , Marcio Ajudarte Lopes DDS, MSc, PhD , Luiz Paulo Kowalski MD, PhD , Anna Luíza Damaceno Araújo DDS, MSc, PhD , Matheus Cardoso Moraes BSc, MSc, PhD , Pablo Agustin Vargas DDS, MSc, PhD, FRCPath","doi":"10.1016/j.oooo.2025.09.018","DOIUrl":"10.1016/j.oooo.2025.09.018","url":null,"abstract":"<div><h3>Objective</h3><div>Although artificial intelligence tools show promise for enhancing the diagnosis of head and neck lesions, few studies have tested these resources for the microscopic diagnosis of salivary gland tumors. Specifically, the microscopic differentiation between acinic cell carcinoma and secretory carcinoma has never been addressed in this context. Therefore, this exploratory study aimed to comparatively evaluate the feasibility of applying convolutional neural networks for the microscopic differentiation between acinic cell carcinomas and secretory carcinomas.</div></div><div><h3>Methods</h3><div>A cross-sectional study using whole-slide images from 46 patients with acinic cell carcinoma (n = 26) or secretory carcinoma (n = 20) was conducted. Eight CNNs (ResNet-50, InceptionV3, VGG16, Xception, MobileNet, DenseNet121, EfficientNetB0, and EfficientNetV2B0) were trained and evaluated for accuracy, sensitivity, specificity, F1-score, and AUC. Performance was measured in training, validation, and test subsets. Accuracy and loss curves were also presented.</div></div><div><h3>Results</h3><div>InceptionV3 demonstrated the best overall performance, with the lowest loss (1.39), highest accuracy (0.81), sensitivity (0.90), and F1-score (0.81). VGG16 achieved the highest AUC (0.86) and precision (0.77). DenseNet121 showed the lowest performance in terms of accuracy (0.65) and F1-Score (0.52), but the highest specificity (0.85).</div></div><div><h3>Conclusion</h3><div>This proof-of-concept study suggests that convolutional neural networks may be feasible tools to support the microscopic differentiation between acinic cell carcinoma and secretory carcinoma. The performance of these models critically depends on the size of the dataset and the quality of annotations. The findings should be interpreted cautiously given the limited dataset and potential sources of bias. Further validation with larger, multicenter datasets is needed before any clinical application can be considered.</div></div>","PeriodicalId":49010,"journal":{"name":"Oral Surgery Oral Medicine Oral Pathology Oral Radiology","volume":"141 3","pages":"Pages 387-399"},"PeriodicalIF":1.9,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146039959","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Melanie E. Miller MS , William R. Bowling MS , Tyrone F. Borders MS, PhD , Nayeon Kim MS , Ian A. Boggero PhD
{"title":"Patient-reported feasibility, acceptability, and satisfaction of psychological telehealth orofacial pain interventions: a mixed-methods study","authors":"Melanie E. Miller MS , William R. Bowling MS , Tyrone F. Borders MS, PhD , Nayeon Kim MS , Ian A. Boggero PhD","doi":"10.1016/j.oooo.2025.10.009","DOIUrl":"10.1016/j.oooo.2025.10.009","url":null,"abstract":"<div><h3>Objective</h3><div>Physical Self-Regulation (PSR) is a brief psychological intervention with demonstrated efficacy for use with orofacial pain populations, but it is unclear whether patients find PSR feasible when delivered via telehealth. Our aim was to evaluate the feasibility, acceptability, and satisfaction of PSR via telehealth among treatment-seeking adults with chronic orofacial pain.</div></div><div><h3>Study Design</h3><div>A convergent mixed-methods design was used. Twenty-eight treatment-seeking adults were recruited from a university-affiliated orofacial pain clinic and received three telehealth-delivered PSR sessions. Twenty-two completed all three sessions and eighteen also completed qualitative interviews. Measures of feasibility (Treatment Evaluation Questionnaire) and acceptability/adherence (Treatment Acceptability and Adherence Scale) were completed after sessions 1 and 2. Satisfaction (Treatment Satisfaction Questionnaire) was completed after session 3. Interviews explored participant’s experiences and were analyzed using content analysis.</div></div><div><h3>Results</h3><div>Participants reported high perceived feasibility and acceptability/adherence at all timepoints. Perceived feasibility improved from PSR session 1 to session 2 (<em>P = .0</em>22). Following session 3, participants reported high satisfaction (M=3.59/4.00). Qualitative findings identified five themes: initial skepticism followed by optimism, improved functioning, convenience, low prior awareness of PSR, and feelings of empowerment.</div></div><div><h3>Conclusions</h3><div>Telehealth-delivered PSR was perceived as feasible, acceptable, and satisfying, supporting PSR’s potential as an implementable and scalable adjuvant telehealth therapy.</div></div>","PeriodicalId":49010,"journal":{"name":"Oral Surgery Oral Medicine Oral Pathology Oral Radiology","volume":"141 3","pages":"Pages 334-342"},"PeriodicalIF":1.9,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145641754","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}