Oral Surgery Oral Medicine Oral Pathology Oral Radiology最新文献

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Metastatic adenocarcinoma: a case report of multiple primary tumors in the oral cavity 转移性腺癌:口腔多发原发肿瘤1例报告
IF 2 3区 医学
Oral Surgery Oral Medicine Oral Pathology Oral Radiology Pub Date : 2025-03-14 DOI: 10.1016/j.oooo.2025.01.058
Juliana Meneses Montalvão Costa, Liliana Wolf Braun, Thais Lins Soares Leite, Luis Afonso Tochetto, Marco Antonio Trevizani Martins, Vinicius Coelho Carrard, Manoela Domingues Martins
{"title":"Metastatic adenocarcinoma: a case report of multiple primary tumors in the oral cavity","authors":"Juliana Meneses Montalvão Costa,&nbsp;Liliana Wolf Braun,&nbsp;Thais Lins Soares Leite,&nbsp;Luis Afonso Tochetto,&nbsp;Marco Antonio Trevizani Martins,&nbsp;Vinicius Coelho Carrard,&nbsp;Manoela Domingues Martins","doi":"10.1016/j.oooo.2025.01.058","DOIUrl":"10.1016/j.oooo.2025.01.058","url":null,"abstract":"<div><div>A 59-year-old male patient was referred to the oral medicine department because of persistent sialorrhea and dysphagia resulting from squamous cell carcinoma of the esophagus that was treated with radiotherapy in 2021. The patient was taking omeprazole 20 mg daily and denied smoking or alcohol consumption regularly. During evaluation, a hard asymptomatic nodule was identified on the right lateral border of the patient's tongue. An incisional biopsy revealed adenosquamous carcinoma, and the patient underwent partial glossectomy with supraomohyoid neck dissection. Two months later, the patient developed a hard submucosal nodule on the lower lip, which was diagnosed as conventional polymorphic adenocarcinoma. Metastatic lesions of polymorphic adenocarcinoma were also detected in the right temporal region, eyebrow, and upper and lower lips. Palliative chemotherapy was recommended, consisting of 8 cycles of carboplatin AUC 5 and paclitaxel 175 mg/m<sup>2</sup> administered every 21 days, followed by the FOLFOX (leucovorin, fluorouracil, and oxaliplatin) second-line chemotherapy protocol.</div></div>","PeriodicalId":49010,"journal":{"name":"Oral Surgery Oral Medicine Oral Pathology Oral Radiology","volume":"139 5","pages":"Page e11"},"PeriodicalIF":2.0,"publicationDate":"2025-03-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143619938","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Large myofibroma in the mandible of an adult woman: a case report 成年女性下颌骨大肌纤维瘤1例
IF 2 3区 医学
Oral Surgery Oral Medicine Oral Pathology Oral Radiology Pub Date : 2025-03-14 DOI: 10.1016/j.oooo.2025.01.028
Caroline Alfaia-Silva, José Renato Brandão, Tulio Silva Rosa, Filipe Modolo Siqueira, Elena Riet Correa Rivero, Rogério de Oliveira Gondak, Ricardo Luiz Cavalcanti de Albuquerque-Júnior
{"title":"Large myofibroma in the mandible of an adult woman: a case report","authors":"Caroline Alfaia-Silva,&nbsp;José Renato Brandão,&nbsp;Tulio Silva Rosa,&nbsp;Filipe Modolo Siqueira,&nbsp;Elena Riet Correa Rivero,&nbsp;Rogério de Oliveira Gondak,&nbsp;Ricardo Luiz Cavalcanti de Albuquerque-Júnior","doi":"10.1016/j.oooo.2025.01.028","DOIUrl":"10.1016/j.oooo.2025.01.028","url":null,"abstract":"<div><div>The myofibroma is a benign mesenchymal neoplasm of perivascular myoid cells that forms a spectrum with myopericytoma. We report the case of a 39-year-old woman with a unilocular radiolucent lesion in the mandible, extending from the mesial of the left first molar to near the incisura. Computed tomography showed a well-defined hypodense lesion. Incisional biopsy revealed a biphasic proliferation of round to spindle-shaped cells, with various fascicular patterns and narrow blood vessels surrounded by tumor cells. The stroma was predominantly myxoid, with low mitotic activity. Adjacent to the lesion, densely collagenized fibrous connective tissue, peripheral nerve fibers, and fragments of mucoserous acini from salivary glands were observed. Immunohistochemistry was positive for SMA and podoplanin. The diagnosis of myofibroma was established, highlighting its histological morphology and adjacent characteristics. Intraosseous myofibroma requires meticulous clinical-histological-radiological investigation, combined with an immunohistochemical marker panel, aiding in its diagnosis. The patient is awaiting tumor removal.</div></div>","PeriodicalId":49010,"journal":{"name":"Oral Surgery Oral Medicine Oral Pathology Oral Radiology","volume":"139 5","pages":"Page e5"},"PeriodicalIF":2.0,"publicationDate":"2025-03-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143620129","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Unusual gingival reaction related to foreign body hydroxyapatite: a case report 异物羟基磷灰石所致牙龈异常反应1例
IF 2 3区 医学
Oral Surgery Oral Medicine Oral Pathology Oral Radiology Pub Date : 2025-03-14 DOI: 10.1016/j.oooo.2025.01.017
Josefina Martínez-Ramírez, Sibele Nascimento de Aquino, Hélen Kaline Farias Bezerra, Mario Fernando de Góes, Alan Roger Santos-Silva, Pablo Agustin Vargas, Márcio Ajudarte Lopes
{"title":"Unusual gingival reaction related to foreign body hydroxyapatite: a case report","authors":"Josefina Martínez-Ramírez,&nbsp;Sibele Nascimento de Aquino,&nbsp;Hélen Kaline Farias Bezerra,&nbsp;Mario Fernando de Góes,&nbsp;Alan Roger Santos-Silva,&nbsp;Pablo Agustin Vargas,&nbsp;Márcio Ajudarte Lopes","doi":"10.1016/j.oooo.2025.01.017","DOIUrl":"10.1016/j.oooo.2025.01.017","url":null,"abstract":"<div><div>A 56-year-old woman was referred for evaluation and management of 2 asymptomatic vestibular gingival lesions in the areas of both upper lateral incisors. These 2 teeth were missing, and the areas were rehabilitated with dental implants and crowns. The patient reported that was previously treated in another service with systematic antibiotics and antiseptic mouthwash without resolution. She denied tobacco and alcohol use and her medical history includes a stroke medicated with clopidogrel. Clinical examination revealed 2 nodular lesions with erythematous and whitish areas on the marginal gingiva, with approximately 1 cm each. Cone beam computed tomography revealed extraosseous hyperdense particles along the bilateral buccal cortical bone of the dental implants. Microscopic examination showed intense chronic inflammation associated with numerous birefringent structures with rectangular and triangular shapes immediately subjacent to the epithelium. Energy-dispersive X-ray analysis revealed calcium and phosphate as the main elements of the foreign body, allowing comparison with pure hydroxyapatite to confirm the similarity in composition. The case is especially unique due to the identification of an enlarged gingival reaction to hydroxyapatite.</div></div>","PeriodicalId":49010,"journal":{"name":"Oral Surgery Oral Medicine Oral Pathology Oral Radiology","volume":"139 5","pages":"Page e3"},"PeriodicalIF":2.0,"publicationDate":"2025-03-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143620133","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Amyloidosis associated with multiple myeloma: case report 淀粉样变合并多发性骨髓瘤1例
IF 2 3区 医学
Oral Surgery Oral Medicine Oral Pathology Oral Radiology Pub Date : 2025-03-14 DOI: 10.1016/j.oooo.2025.01.063
Caroline Fernandes da Costa, Caroline de Almeida Reis, Jennifer Maia Alves da Silva, Julliany Taverny Sousa, Patrícia Teixeira de Oliveira, Joabe dos Santos Pereira, Lélia Maria Guedes Queiroz
{"title":"Amyloidosis associated with multiple myeloma: case report","authors":"Caroline Fernandes da Costa,&nbsp;Caroline de Almeida Reis,&nbsp;Jennifer Maia Alves da Silva,&nbsp;Julliany Taverny Sousa,&nbsp;Patrícia Teixeira de Oliveira,&nbsp;Joabe dos Santos Pereira,&nbsp;Lélia Maria Guedes Queiroz","doi":"10.1016/j.oooo.2025.01.063","DOIUrl":"10.1016/j.oooo.2025.01.063","url":null,"abstract":"<div><div>Amyloidosis is a debilitating disease with systemic or local manifestation characterized by progressive extracellular deposition of insoluble proteins that can affect multiple organs. A 72-year-old male patient, with a history of hyperthyroidism, dysphagia, and weight loss, was referred by the physician due to edema and erythema on the tongue. Upon extraoral examination, petechiae near the eyes and hemorrhagic discharge in the right eye were observed. Intraoral examination revealed macroglossia and normochromic nodular lesions on the tongue, as well as petechiae on the palate and buccal mucosa. With clinical suspicion of amyloidosis, an incisional biopsy was performed. Histopathological examination revealed extracellular deposits of homogeneous eosinophilic amorphous material, suggestive of amyloidosis. The diagnosis was confirmed through histochemical examination with Congo red stain. The patient was referred to the medical service for investigation of multifocal organ involvement, was diagnosed with multiple myeloma, and is currently undergoing chemotherapy treatment.</div></div>","PeriodicalId":49010,"journal":{"name":"Oral Surgery Oral Medicine Oral Pathology Oral Radiology","volume":"139 5","pages":"Page e12"},"PeriodicalIF":2.0,"publicationDate":"2025-03-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143620697","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Case report: extranodal T-cell lymphoma (natural killer) mimicking a dentoalveolar abscess 病例报告:结外t细胞淋巴瘤(自然杀手)模拟牙槽脓肿
IF 2 3区 医学
Oral Surgery Oral Medicine Oral Pathology Oral Radiology Pub Date : 2025-03-14 DOI: 10.1016/j.oooo.2025.01.076
Núbia Rafaelle Oliveira de Meneses, Luciana Munhoz, Erika Antonia dos Anjos Ramos, Alice Souza Villar Cassimiro Fonseca, Lucila Massu Yoshizaki Akinaga Moreira, Daniela Miranda Richarte de Andrade Salgado, Claudio Costa
{"title":"Case report: extranodal T-cell lymphoma (natural killer) mimicking a dentoalveolar abscess","authors":"Núbia Rafaelle Oliveira de Meneses,&nbsp;Luciana Munhoz,&nbsp;Erika Antonia dos Anjos Ramos,&nbsp;Alice Souza Villar Cassimiro Fonseca,&nbsp;Lucila Massu Yoshizaki Akinaga Moreira,&nbsp;Daniela Miranda Richarte de Andrade Salgado,&nbsp;Claudio Costa","doi":"10.1016/j.oooo.2025.01.076","DOIUrl":"10.1016/j.oooo.2025.01.076","url":null,"abstract":"<div><div>T-cell lymphoma (natural killer) is a malignant neoplasm rarely developing extranodal and may mimic odontogenic alterations in the maxillofacial region. A pheoderma 41-year-old woman came to the dental service complaining of painful orofacial symptoms and fever. Clinical examination revealed intra- and extra-oral swelling on the left cheek, marked mobility, and endodontic involvement of the ipsilateral upper molars. The primary diagnostic hypothesis was an acute dentoalveolar abscess, with an initial approach of antibiotic therapy. After 2 weeks, the patients’ pain complaint was persistent, and rapid progression of the facial edema was observed. A computed tomography scan was carried out, which showed an image with soft tissue density, promoting discontinuity of the anterior and lateral walls of the left maxillary sinus. The pathological examination revealed a malignant neoplasm, whose histological type characterizes extranodal T-cell lymphoma (ENKL) in the left maxillary sinus. The proposed treatment for this condition includes radiotherapy and chemotherapy.</div></div>","PeriodicalId":49010,"journal":{"name":"Oral Surgery Oral Medicine Oral Pathology Oral Radiology","volume":"139 5","pages":"Pages e14-e15"},"PeriodicalIF":2.0,"publicationDate":"2025-03-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143620698","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Adenoid ameloblastoma with dentinoid: a case report 腺样成釉细胞瘤合并牙本质1例
IF 2 3区 医学
Oral Surgery Oral Medicine Oral Pathology Oral Radiology Pub Date : 2025-03-14 DOI: 10.1016/j.oooo.2025.01.071
Eduardo dos Santos Vidal, William Cezar da Silveira, Hélen Kaline Farias Bezerra, Camila Cerantula Moura, Leandro Eduardo Klüppel, Pablo Agustin Vargas, Heliton Gustavo de Lima
{"title":"Adenoid ameloblastoma with dentinoid: a case report","authors":"Eduardo dos Santos Vidal,&nbsp;William Cezar da Silveira,&nbsp;Hélen Kaline Farias Bezerra,&nbsp;Camila Cerantula Moura,&nbsp;Leandro Eduardo Klüppel,&nbsp;Pablo Agustin Vargas,&nbsp;Heliton Gustavo de Lima","doi":"10.1016/j.oooo.2025.01.071","DOIUrl":"10.1016/j.oooo.2025.01.071","url":null,"abstract":"<div><div>A 32-year-old Caucasian female presented with a friable, hemorrhagic intraoral nodule associated with impacted tooth 48, exhibiting a roseus coloration, soft consistency, and a sessile with a 2 cm extension, evolving over a 3-year period. Cone-beam computed tomography revealed intraosseous evidence of a hypodense region associated with tooth 48. In the axial section, bone cortex expansion and buccal/lingual fenestrations were noted. Initial diagnostic considerations included dentigerous cyst and ameloblastoma. An incisional biopsy confirmed the diagnosis as conventional ameloblastoma with an acanthomatous pattern. Following complete lesion removal, microscopic analysis revealed, in addition to the ameloblastoma component, duct-like structures, a cribriform architecture, and the presence of dentinoid material, supported by positive immunohistochemical stains (CK19, CK14, β-catenin) and low Ki-67 (&lt;5%), confirming adenoid ameloblastoma with dentinoid. While studies have documented cases of this new entity in the gnathic bones, further characterization is crucial for understanding its etiopathogenesis and biological behavior.</div></div>","PeriodicalId":49010,"journal":{"name":"Oral Surgery Oral Medicine Oral Pathology Oral Radiology","volume":"139 5","pages":"Pages e13-e14"},"PeriodicalIF":2.0,"publicationDate":"2025-03-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143620825","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Information for Readers 读者资讯
IF 2 3区 医学
Oral Surgery Oral Medicine Oral Pathology Oral Radiology Pub Date : 2025-03-14 DOI: 10.1016/S2212-4403(25)00790-4
{"title":"Information for Readers","authors":"","doi":"10.1016/S2212-4403(25)00790-4","DOIUrl":"10.1016/S2212-4403(25)00790-4","url":null,"abstract":"","PeriodicalId":49010,"journal":{"name":"Oral Surgery Oral Medicine Oral Pathology Oral Radiology","volume":"139 5","pages":"Page A6"},"PeriodicalIF":2.0,"publicationDate":"2025-03-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143619430","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Screening of erythematous petechiae and macules as indicators of systemic diseases: a case report 筛选红斑点和斑点作为全身性疾病的指标:1例报告
IF 2 3区 医学
Oral Surgery Oral Medicine Oral Pathology Oral Radiology Pub Date : 2025-03-14 DOI: 10.1016/j.oooo.2025.01.065
Nara Rúbia Pereira de Siqueira, Filipe Moreira Biokino, Vanessa Milani, Douglas Rangel Goulart, Diego Antonio Costa Arantes, Elismauro Francisco de Mendonça, Rejane Faria Ribeiro-Rotta
{"title":"Screening of erythematous petechiae and macules as indicators of systemic diseases: a case report","authors":"Nara Rúbia Pereira de Siqueira,&nbsp;Filipe Moreira Biokino,&nbsp;Vanessa Milani,&nbsp;Douglas Rangel Goulart,&nbsp;Diego Antonio Costa Arantes,&nbsp;Elismauro Francisco de Mendonça,&nbsp;Rejane Faria Ribeiro-Rotta","doi":"10.1016/j.oooo.2025.01.065","DOIUrl":"10.1016/j.oooo.2025.01.065","url":null,"abstract":"<div><div>Oral mucosa alterations can be part of screening for various diseases. A 39-year-old white woman, with lower lip erythematous macules for 5 years, worsting in 2 months with bleeding upon minimal trauma and healing delay. History of 10 years of working sun overexposure, treated anemia, no chronic medication. Current blood tests are within normal limits. Labial mucosa, gingiva, dorsum of the tongue, buccal mucosa, and fingertips presented erythematous petechiae. Lower lip incisional biopsy reported capillary hemangioma. Clinical diagnosis pointed toward hereditary hemorrhagic telangiectasia, as the patient reported recurrent spontaneous epistaxis and her 18-year-old daughter exhibited similar symptoms. Differential diagnosis was considered for CREST syndrome. She was referred to a physician to investigate possible arteriovenous malformations involving the lungs, liver, or central nervous system. Lip lesions were successfully treated with ethanolamine. The dentist can play a decisive role in the diagnosis of systemic diseases if he thoroughly explores the whole patient's history.</div></div>","PeriodicalId":49010,"journal":{"name":"Oral Surgery Oral Medicine Oral Pathology Oral Radiology","volume":"139 5","pages":"Page e12"},"PeriodicalIF":2.0,"publicationDate":"2025-03-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143619868","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Oral Kaposis sarcoma report of 4 cases 口腔Kaposis肉瘤4例报告
IF 2 3区 医学
Oral Surgery Oral Medicine Oral Pathology Oral Radiology Pub Date : 2025-03-14 DOI: 10.1016/j.oooo.2025.01.060
Yuri Kalinin, Vanessa Cristina de Branco Gonçalves, Ivan José Correia-Neto, Suellen Vieira do Nascimento, Lucas Lacerda de Souza
{"title":"Oral Kaposis sarcoma report of 4 cases","authors":"Yuri Kalinin,&nbsp;Vanessa Cristina de Branco Gonçalves,&nbsp;Ivan José Correia-Neto,&nbsp;Suellen Vieira do Nascimento,&nbsp;Lucas Lacerda de Souza","doi":"10.1016/j.oooo.2025.01.060","DOIUrl":"10.1016/j.oooo.2025.01.060","url":null,"abstract":"<div><div>Oral Kaposi's Sarcoma (KS) presents a significant diagnostic challenge and is an important indicator of HIV/AIDS. This study aims to present a case series involving 4 male patients with a mean age of 28.5 years (range 22-39). The patients exhibited reddish, ulcerated, and bleeding lesions on the hard palate and gingiva, along with disseminated lesions. Incisional biopsies revealed spindle cell proliferation and slit-like vascular spaces, with immunohistochemistry positive for CD34 and HHV-8 markers, confirming the diagnosis of KS. For 2 patients, oral KS was the initial sign of HIV infection, which was also indicated by increased viral loads and decreased CD4/T cell counts. All patients were referred for treatment and have been under follow-up for an average of 30.5 months (range 2-48). This highlights the importance of recognizing oral KS as an early indicator of HIV and advocates for a comprehensive, multidisciplinary management approach to systemic diseases.</div></div>","PeriodicalId":49010,"journal":{"name":"Oral Surgery Oral Medicine Oral Pathology Oral Radiology","volume":"139 5","pages":"Page e11"},"PeriodicalIF":2.0,"publicationDate":"2025-03-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143619940","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Central giant cell lesion in the maxilla: from differential diagnosis of brown tumor to death due to COVID-19 上颌骨中央巨细胞病变:从棕色肿瘤的鉴别诊断到COVID-19死亡
IF 2 3区 医学
Oral Surgery Oral Medicine Oral Pathology Oral Radiology Pub Date : 2025-03-14 DOI: 10.1016/j.oooo.2025.01.048
Thiago Macedo Marques, Livia Bino Marques
{"title":"Central giant cell lesion in the maxilla: from differential diagnosis of brown tumor to death due to COVID-19","authors":"Thiago Macedo Marques,&nbsp;Livia Bino Marques","doi":"10.1016/j.oooo.2025.01.048","DOIUrl":"10.1016/j.oooo.2025.01.048","url":null,"abstract":"<div><div>A 28-year-old female patient, presented with a nodule in the right maxilla for approximately 60 days, which worsened following the extraction of teeth 16 and 17 due to a suspected dental focus lesion. Intraoral examination revealed a single tumor extending from the palate to the alveolar ridge, with an intact surface on the palate and ulcerated on the ridge. No cervical lymphadenopathy was observed on extrabuccal examination. The patient reported spontaneous pain, partially alleviated by analgesics. Laboratory tests indicated elevated levels of urea and creatinine. An incisional biopsy was performed, and histological analysis suggested a Central Giant Cell Lesion. The possibility of a Brown Tumor of Hyperparathyroidism was considered due to the laboratory findings, but it was not confirmed due to the patient's death from COVID-19 during hospitalization for dialytic therapy following the exacerbation of renal disease.</div></div>","PeriodicalId":49010,"journal":{"name":"Oral Surgery Oral Medicine Oral Pathology Oral Radiology","volume":"139 5","pages":"Page e9"},"PeriodicalIF":2.0,"publicationDate":"2025-03-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143619942","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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