Oral Surgery Oral Medicine Oral Pathology Oral Radiology最新文献

Use of biological information in the diagnostic process: a glance into the future of dentistry. 在诊断过程中使用生物信息：牙科未来一瞥》。

IF 2 3区医学

Oral Surgery Oral Medicine Oral Pathology Oral Radiology Pub Date : 2025-02-01 Epub Date: 2024-10-05 DOI: 10.1016/j.oooo.2024.09.009

Katherine France, Craig S Miller

引用次数: 0

Impact of radiotherapy on peripheral T lymphocytes in hypopharyngeal squamous cell carcinoma. 放疗对下咽鳞状细胞癌患者外周 T 淋巴细胞的影响

IF 2 3区医学

Oral Surgery Oral Medicine Oral Pathology Oral Radiology Pub Date : 2025-02-01 Epub Date: 2024-10-29 DOI: 10.1016/j.oooo.2024.10.080

Hanqing Lin, Yu Heng, Xiaoke Zhu, Tian Wang, Lei Tao

{"title":"Impact of radiotherapy on peripheral T lymphocytes in hypopharyngeal squamous cell carcinoma.","authors":"Hanqing Lin, Yu Heng, Xiaoke Zhu, Tian Wang, Lei Tao","doi":"10.1016/j.oooo.2024.10.080","DOIUrl":"10.1016/j.oooo.2024.10.080","url":null,"abstract":"Background: To investigate the impact of radiotherapy (RT) on the distribution and function of peripheral CD8+ T lymphocytes in patients with hypopharyngeal squamous cell carcinoma (HPSCC).Methods: A total of 105 HPSCC patients who underwent definitive RT were enrolled. Baseline levels of peripheral immune cells were obtained, and their alteration during RT was evaluated. Flow cytometry was used to analyze T-cell distribution, cytokine secretion, and CD8+ T lymphocyte proliferation capacity.Results: Lymphocyte count significantly decreased following radiation and remained in a low level after 1 year of RT. CD3+ T lymphocyte counts decreased significantly, and the CD4+/CD8+ ratio increased in HPSCC patients following radiation. The secretion of IFN-γ from peripheral CD8+ T lymphocytes was significantly reduced after irradiation, while the secretion of TNF-α and perforin did not change significantly. Furthermore, the proliferation capacity of peripheral CD8+ T lymphocytes was decreased following RT.Conclusions: RT significantly decreased the number of peripheral T lymphocytes and impaired the secretory function and proliferation ability of CD8+ T lymphocytes in HPSCC patients. These findings provide insight into the mechanisms underlying the therapeutic effects of RT on HPSCC and have implications for optimizing treatment strategies.","PeriodicalId":49010,"journal":{"name":"Oral Surgery Oral Medicine Oral Pathology Oral Radiology","volume":" ","pages":"220-228"},"PeriodicalIF":2.0,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142630966","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Adenomatoid hyperplasia of minor salivary glands: a systematic review. 小唾液腺腺瘤样增生：系统综述。

IF 2 3区医学

Oral Surgery Oral Medicine Oral Pathology Oral Radiology Pub Date : 2025-02-01 Epub Date: 2024-10-30 DOI: 10.1016/j.oooo.2024.10.081

Gabriel Lima Braz, Ana Carolina Uchoa Vasconcelos, Ana Paula Neutzling Gomes, Camila Barcellos Calderipe, Alini Cardoso Soares

{"title":"Adenomatoid hyperplasia of minor salivary glands: a systematic review.","authors":"Gabriel Lima Braz, Ana Carolina Uchoa Vasconcelos, Ana Paula Neutzling Gomes, Camila Barcellos Calderipe, Alini Cardoso Soares","doi":"10.1016/j.oooo.2024.10.081","DOIUrl":"10.1016/j.oooo.2024.10.081","url":null,"abstract":"Objective: To systematically review available data regarding adenomatoid hyperplasia of minor salivary glands (AHMSG).Study design: Electronic searches were performed in six databases and gray literature. The risk of bias was assessed using the Joanna Briggs Institute tool.Results: Forty studies reporting 121 cases of AHMSG were included. There is a male predominance (n = 72/64.29%), with individuals in their fourth and fifth decade of life being the most affected. The palate was the main anatomical location (n = 90/74.39%), and most lesions presented as single, asymptomatic nodules. The mean size of AHMSGs was 1.48 ± 0.77 cm, and the mean evolution time was 16.84 ± 25.67 months. Immunohistochemical evaluation in three cases (2.48%) showed a low labeling index for Ki-67 (n = 2/66.67%) and proliferating cell nuclear antigen (n = 1/33.33%).Conclusions: AHMSG is an uncommon benign lesion with no tendency to recur after initial surgical removal. The main histological features include an abundant proliferation of glandular acini, occasional ductal dilation, and sometimes the presence of inflammatory infiltrate. Pathologists and clinicians should be aware of AHMSG, as it can closely resemble both benign and malignant salivary gland lesions.","PeriodicalId":49010,"journal":{"name":"Oral Surgery Oral Medicine Oral Pathology Oral Radiology","volume":" ","pages":"229-241"},"PeriodicalIF":2.0,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142689377","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

An ex vivo comparison of near-infrared Raman spectroscopy and cone beam computed tomography in the assessment of bone, dental hard tissues, and bone graft materials. 近红外拉曼光谱和锥形束计算机断层扫描在评估骨骼、牙科硬组织和植骨材料方面的体内外比较。

IF 2 3区医学

Oral Surgery Oral Medicine Oral Pathology Oral Radiology Pub Date : 2025-02-01 Epub Date: 2024-10-17 DOI: 10.1016/j.oooo.2024.10.076

Anusha Vaddi, Aditya Tadinada, Alix Deymier

{"title":"An ex vivo comparison of near-infrared Raman spectroscopy and cone beam computed tomography in the assessment of bone, dental hard tissues, and bone graft materials.","authors":"Anusha Vaddi, Aditya Tadinada, Alix Deymier","doi":"10.1016/j.oooo.2024.10.076","DOIUrl":"10.1016/j.oooo.2024.10.076","url":null,"abstract":"Objective: To evaluate the potential of near-infrared Raman spectroscopy (RS) in distinguishing between various types of bone, dental hard tissues, and bone graft materials, and to determine the correlation between pixel intensity values (PIVs) in cone beam computed tomography (CBCT) and Raman values.Study design: A thinly sliced section of mandible was utilized to evaluate cancellous and cortical bone. Extracted human teeth were used to prepare the enamel and dentin samples. Bone graft materials were tested by compacting them into edentulous tooth sockets in a dry human mandible. CBCT and RS scans of the samples were performed. The following RS outcomes were evaluated: 960 cm-1 phosphate peak location and width, carbonate:phosphate ratio, mineral:matrix ratio, and collagen coiling ratio. One-way ANOVA and primary component analysis (PCA) statistics were used to assess RS outcomes.Results: The 960 cm-1 phosphate peak location was able to effectively differentiate between various tissues and graft materials. PCA of the spectra successfully differentiated native bone from graft materials, underscoring the tissue characterization capability of RS. Varied correlations between RS outcomes and CBCT PIVs were observed.Conclusions: Various parameters of RS can differentiate between cancellous bone, cortical bone, dental hard tissues, and bone graft materials. The varied correlations between Raman parameters and CBCT PIVs warrant further research to clarify the nature of these relationships.","PeriodicalId":49010,"journal":{"name":"Oral Surgery Oral Medicine Oral Pathology Oral Radiology","volume":" ","pages":"248-259"},"PeriodicalIF":2.0,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142741066","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Oral manifestations of peripheral T cell lymphoma, not otherwise specified: case series and review of the current literature. 非特异性外周 T 细胞淋巴瘤的口腔表现：病例系列和现有文献综述。

IF 2 3区医学

Oral Surgery Oral Medicine Oral Pathology Oral Radiology Pub Date : 2025-02-01 Epub Date: 2024-08-17 DOI: 10.1016/j.oooo.2024.08.011

Eduardo Morato de Oliveira, Cinthia Veronica Bardález Lopéz de Cáceres, Carla Isabelly Fernandes-Rodrigues, Paulo Victor Mendes Penafort, Juan Manuel Arteaga Legarrea, Nathalia Rodrigues Gomes, Hélder Antônio Rebelo Pontes, Pablo Agustin Vargas, José Narciso Rosa Assunção Júnior, Ciro Dantas Soares, Felipe Paiva Fonseca

{"title":"Oral manifestations of peripheral T cell lymphoma, not otherwise specified: case series and review of the current literature.","authors":"Eduardo Morato de Oliveira, Cinthia Veronica Bardález Lopéz de Cáceres, Carla Isabelly Fernandes-Rodrigues, Paulo Victor Mendes Penafort, Juan Manuel Arteaga Legarrea, Nathalia Rodrigues Gomes, Hélder Antônio Rebelo Pontes, Pablo Agustin Vargas, José Narciso Rosa Assunção Júnior, Ciro Dantas Soares, Felipe Paiva Fonseca","doi":"10.1016/j.oooo.2024.08.011","DOIUrl":"10.1016/j.oooo.2024.08.011","url":null,"abstract":"Objective: The objective of this study was to describe a series of peripheral T-cell lymphoma, not otherwise specified (PTCL NOS) affecting the oral cavity and to review the available literature.Study design: Cases diagnosed as PTCL-NOS affecting the oral cavity were retrospectively retrieved from pathology files. Original hematoxylin and eosin-stained slides and immunohistochemical reactions were reviewed for microscopic confirmation. The presence of Epstein-Barr virus (EBV) was investigated by in situ hybridization. Clinical and follow-up data were retrieved from patients' pathology and medical files.Results: A total of 5 cases were obtained with a mean age of 51.8 years old, 3 male patients and 2 female patients. Three cases affected the palate and 2 cases affected the gingiva, whereas 1 case affected the maxillary bone. Tumors presented as destructive, infiltrative, and painful lesions causing swelling, ulceration, and tissue necrosis. All cases exhibited CD3 expression. GATA3 was expressed in 3 cases. Four patients were deceased of the disease during follow-up.Conclusions: PTCL NOS affecting the oral cavity is rare and usually present as a very aggressive disease, associated with a poor prognosis and dismal outcome. (Oral Surg Oral Med Oral Pathol Oral Radiol YEAR;VOL:page range).","PeriodicalId":49010,"journal":{"name":"Oral Surgery Oral Medicine Oral Pathology Oral Radiology","volume":" ","pages":"e37-e45"},"PeriodicalIF":2.0,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142113857","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Prescription of potentially inappropriate medications in older adults: data from a dental institution. 老年人处方可能不当的药物；来自一家牙科机构的数据。

IF 2 3区医学

Oral Surgery Oral Medicine Oral Pathology Oral Radiology Pub Date : 2025-02-01 Epub Date: 2024-09-16 DOI: 10.1016/j.oooo.2024.09.006

Arwa Farag, Matthew Finkelman, Scarlet Charmelo-Silva, Christina Sun, Madison Mondry, Mohammed Bindakhil

{"title":"Prescription of potentially inappropriate medications in older adults: data from a dental institution.","authors":"Arwa Farag, Matthew Finkelman, Scarlet Charmelo-Silva, Christina Sun, Madison Mondry, Mohammed Bindakhil","doi":"10.1016/j.oooo.2024.09.006","DOIUrl":"10.1016/j.oooo.2024.09.006","url":null,"abstract":"Objectives: The objectives of this study were to determine the types and frequency of potentially inappropriate medications (PIMs) prescribed to geriatric patients while considering the patients' age groups and their American Society of Anesthesiologists (ASA) physical status.Study design: We performed a 5-year retrospective chart review of patients aged 65 years and above who were seen in a dental institution. Patients' medical history, PIM prescriptions, and prescribers' specialty and professional status were analyzed.Results: Out of 10,675 geriatric patients identified, 6.2% (n = 662) received PIM prescriptions. Of those, 77% received one PIM whereas the others (23%) received anywhere between 2 and 6; the majority (73.7%) of these 662 patients fell within an ASA III physical status. Nonsteroidal anti-inflammatory drugs (NSAIDs) were the most prescribed PIM (provided to 60.1% of subjects) followed by opioids (provided to 32.5% of subjects). Both NSAIDs and opioids were largely provided by providers in oral and maxillofacial surgery followed by those in restorative dentistry and periodontics. Benzodiazepines were mostly prescribed by endodontics providers, whereas tricyclic antidepressants, muscle relaxants, and anticonvulsants were mostly prescribed by oral medicine providers. Residents prescribed opioids at similar rates to the faculty (P = .78) but exceeded the faculty in prescribing benzodiazepines (P < .001).Conclusion: PIMs were prescribed at low percentages to geriatric patients; however, most prescriptions were provided to patients classified with ASA III status. Further efforts are indicated, at institutional and national levels, to monitor/limit PIMs provided to geriatric population. (Oral Surg Oral Med Oral Pathol Oral Radiol YEAR;VOL:page range).","PeriodicalId":49010,"journal":{"name":"Oral Surgery Oral Medicine Oral Pathology Oral Radiology","volume":" ","pages":"188-200"},"PeriodicalIF":2.0,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142695996","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Spontaneous bacterial peritonitis and soft tissue healing after tooth extraction in liver cirrhosis patients. 肝硬化患者拔牙后的自发性细菌性腹膜炎和软组织愈合。

IF 2 3区医学

Oral Surgery Oral Medicine Oral Pathology Oral Radiology Pub Date : 2025-02-01 Epub Date: 2024-09-15 DOI: 10.1016/j.oooo.2024.09.003

Gustavo Souza Galvão, Juliana Bertoldi Franco, Maria Paula Siqueira de Melo Peres, Gabriela Bănacu Melo, Jefferson R Tenório, Janaina B Medina, Camila de Barros Gallo, Karem L Ortega

{"title":"Spontaneous bacterial peritonitis and soft tissue healing after tooth extraction in liver cirrhosis patients.","authors":"Gustavo Souza Galvão, Juliana Bertoldi Franco, Maria Paula Siqueira de Melo Peres, Gabriela Bănacu Melo, Jefferson R Tenório, Janaina B Medina, Camila de Barros Gallo, Karem L Ortega","doi":"10.1016/j.oooo.2024.09.003","DOIUrl":"10.1016/j.oooo.2024.09.003","url":null,"abstract":"Objective: The objective of this study was to identify the association between tooth extraction and occurrence of spontaneous bacterial peritonitis (SBP) and to assess delayed soft tissue healing of extraction sockets in patients with cirrhosis.Study design: One hundred nineteen participants awaiting liver transplantation who required tooth extraction were included. Seven days before the surgery, the patients underwent panoramic radiography and laboratory examinations. Soft tissue healing was evaluated 7 days after the tooth extraction and medical records were checked after 21 days for development of SBP. The relationship between predictive factors and outcomes was assessed by using multiple binomial logistic regression.Results: One hundred ninety-five teeth were extracted, resulting in 146 alveolar wounds, in which the majority (47%) consisted of alveolar sockets of multirooted teeth. One participant was diagnosed with SBP (Escherichia coli [E. coli]) and another diagnosed with bacterascites (Streptococcus viridans [S. viridans] group), occurring 11 and 6 days after tooth extraction. Poor soft tissue healing was observed in 20 (13.7%) patients, which was correlated to 2 risk factors, that is, jaundice (P = .007, adjusted odds ratio [OR] = 4.91, 95% confidence interval [CI] = 1.56-15.47) and moderate neutropenia (P = .048, adjusted OR = 13.99, 95% CI = 1.02-192.07).Conclusions: No association was found between tooth extraction and SBP in patients with cirrhosis. The delayed soft tissue healing was related to jaundice (hyperbilirubinemia) and moderate neutropenia.","PeriodicalId":49010,"journal":{"name":"Oral Surgery Oral Medicine Oral Pathology Oral Radiology","volume":" ","pages":"177-187"},"PeriodicalIF":2.0,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142367135","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Harnessing machine learning technique to authenticate differentially expressed genes in oral squamous cell carcinoma. 利用机器学习技术鉴别口腔鳞状细胞癌中的差异表达基因

IF 2 3区医学

Oral Surgery Oral Medicine Oral Pathology Oral Radiology Pub Date : 2025-02-01 Epub Date: 2024-10-17 DOI: 10.1016/j.oooo.2024.10.075

Amisha Patel, Saswati Mahapatra, Ashok Kumar Bishoyi, Abhishek Sharma, Abhijit Makwana, Tripti Swarnkar, Anubha Gupta, Prasan Kumar Sahoo, Sejal Shah

{"title":"Harnessing machine learning technique to authenticate differentially expressed genes in oral squamous cell carcinoma.","authors":"Amisha Patel, Saswati Mahapatra, Ashok Kumar Bishoyi, Abhishek Sharma, Abhijit Makwana, Tripti Swarnkar, Anubha Gupta, Prasan Kumar Sahoo, Sejal Shah","doi":"10.1016/j.oooo.2024.10.075","DOIUrl":"10.1016/j.oooo.2024.10.075","url":null,"abstract":"Objective: Advancements in early detection of the disease, prognosis and the development of therapeutic strategies necessitate tumor-specific biomarkers. Despite continuous efforts, no molecular marker has been proven to be an effective therapeutic tool for the early detection of cancer. The study aims to determine diagnostic and prognostic signature genes that may be involved in cancer pathology and hence, may serve as molecular markers.Study design: Eight candidate genes were selected based on our prior study of transcriptomic sequencing and validated in 100 matched pair samples of oral squamous cell carcinoma (OSCC). We further utilized machine learning approaches and examined the diagnostic presentation and predictive ability of the OSCC genes retrieved from publicly available The Cancer Genome Atlas (TCGA) database and compared with our results.Results: We conducted qPCR analysis to validate the expression of each gene and observed that each gene was present in the majority of OSCC samples. The predictive ability of selected genes was stable (with an average accuracy of 84%) across different classifiers. However, on validation with our dataset, it showed 75% accuracy, which might be because of the demographic variation of the samples.Conclusions: The present research outlines cancer-associated molecular biomarkers that might eventually contribute to an enhanced prognosis of cancer patient by identifying novel therapeutic targets.","PeriodicalId":49010,"journal":{"name":"Oral Surgery Oral Medicine Oral Pathology Oral Radiology","volume":" ","pages":"211-219"},"PeriodicalIF":2.0,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142591818","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Prognostic and survival factors in head and neck extra-nodal non-Hodgkin's lymphoma. 头颈部结节外非霍奇金淋巴瘤的预后和生存因素。

IF 2 3区医学

Oral Surgery Oral Medicine Oral Pathology Oral Radiology Pub Date : 2025-02-01 Epub Date: 2024-09-19 DOI: 10.1016/j.oooo.2024.09.007

Alba Bello-Castro, Adrián Mosquera-Orgueira, Francisco Gude-Smpedro, Iván Varela-Aneiros, Javier Seoane-Romero, Benjamín Martin-Biedma, Pablo Castelo-Baz

{"title":"Prognostic and survival factors in head and neck extra-nodal non-Hodgkin's lymphoma.","authors":"Alba Bello-Castro, Adrián Mosquera-Orgueira, Francisco Gude-Smpedro, Iván Varela-Aneiros, Javier Seoane-Romero, Benjamín Martin-Biedma, Pablo Castelo-Baz","doi":"10.1016/j.oooo.2024.09.007","DOIUrl":"10.1016/j.oooo.2024.09.007","url":null,"abstract":"Objective: To make a clinical-biological characterization of this pathology and assess the survival of these patients and the associated prognostic factors.Study design: A retrospective observational study was designed to identify primary extranodal non-Hodgkin lymphomas of the head and neck diagnosed between January 1, 2005, and January 1, 2016. Cases were considered if they presented with a single tumor in situ or if the extranodal component was clinically predominant.Results: A total of 145 patients were included. Localized stages (I-II) were present in 69.3%. Overall, 91.8% were B-cell phenotype, with diffuse large B-cell lymphoma being the most frequent. Overall, 78% of patients were treated with immunochemotherapy. The overall survival at 3 and 5 years was 75% and 73%, respectively. Adverse prognostic factors were: low hemoglobin, elevated ß2-microglobulin, and lactate dehydrogenase (LDH) levels, Eastern Cooperative Oncology Group (ECOG), stage III/IV, and B symptomatology at diagnosis. The progression-free survival at 3 and 5 years was 71% and 68%. Risk factors for relapse were high ß2-microglobulin, high LDH, and stage III-IV at diagnosis.Conclusions: These pathologies show a good response to treatment with immuno-polychemotherapy. Factors associated with a worse prognosis included low hemoglobin, elevated levels of ß2-microglobulin and LDH, elevated ECOG, stage III/IV, and B symptomatology at diagnosis.","PeriodicalId":49010,"journal":{"name":"Oral Surgery Oral Medicine Oral Pathology Oral Radiology","volume":" ","pages":"201-210"},"PeriodicalIF":2.0,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142394579","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Evaluation of mandibular bone structure changes in patients with phenylketonuria through fractal analysis and radiomorphometric indices. 通过分形分析和放射形态测量指数评估苯丙酮尿症患者下颌骨结构的变化。

IF 2 3区医学

Oral Surgery Oral Medicine Oral Pathology Oral Radiology Pub Date : 2025-02-01 Epub Date: 2024-10-05 DOI: 10.1016/j.oooo.2024.09.011

Hazal Duyan Yüksel, Damla Soydan Çabuk, Ali İhsan Çabuk, Burcu Evlice

{"title":"Evaluation of mandibular bone structure changes in patients with phenylketonuria through fractal analysis and radiomorphometric indices.","authors":"Hazal Duyan Yüksel, Damla Soydan Çabuk, Ali İhsan Çabuk, Burcu Evlice","doi":"10.1016/j.oooo.2024.09.011","DOIUrl":"10.1016/j.oooo.2024.09.011","url":null,"abstract":"Objectives: The aim of this study was to evaluate the effect of phenylketonuria (PKU) on mandibular bone structure by comparing the bone of PKU patients with healthy controls using fractal analysis (FA) and the radiomorphometric indices of mandibular cortical width (MCW) and mandibular cortical index (MCI).Study design: In total, 32 patients with PKU were analyzed and compared with the control participants. Regions of interest in panoramic radiographs were selected and the fractal dimension (FD) obtained from FA was calculated. MCW was defined as the cortical thickness of the inferior border of the mandible at the level of the mental foramen. MCI classified the endosteal edge of the mandibular cortex as C1: straight and sharp, C2: the presence lacunar resorption spaces, and C3: distinctly porous and severely eroded. The significance level was P < .05.Results: All FD and MCW values were significantly lower in the PKU patients. The prevalence of C1 was significantly lower and prevalence of C2 was significantly higher in the PKU group.Conclusions: The differences in FD and radiomorphometric indices between patients with PKU and healthy controls may indicate a potential impact of PKU on mandibular bone structure.","PeriodicalId":49010,"journal":{"name":"Oral Surgery Oral Medicine Oral Pathology Oral Radiology","volume":" ","pages":"242-247"},"PeriodicalIF":2.0,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142548480","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0