Oral Surgery Oral Medicine Oral Pathology Oral Radiology最新文献

A yellow submucosal nodule in the buccal mucosa. 口腔粘膜上的黄色粘膜下结节。

IF 2 3区医学

Oral Surgery Oral Medicine Oral Pathology Oral Radiology Pub Date : 2025-01-01 Epub Date: 2024-09-24 DOI: 10.1016/j.oooo.2024.08.021

Celia Bouazza, Ikrame Bouri, Gisele Mainville, Caroline Bissonnette, Catherine Laliberté, Mark Darling, Christina McCord, Adel Kauzman

引用次数: 0

Lack of knowledge, understanding, and delayed attitudes towards health-seeking behavior in oral cancer patients: a qualitative pilot study. 口腔癌患者对寻求健康行为的缺乏了解、理解和延迟态度：一项定性试点研究。

IF 2 3区医学

Oral Surgery Oral Medicine Oral Pathology Oral Radiology Pub Date : 2025-01-01 Epub Date: 2024-09-18 DOI: 10.1016/j.oooo.2024.08.024

Larissa Stefhanne Damasceno de Amorim Póvoa, Daniele Assis Souza, Francielle Silvestre Verner, Rafael Binato Junqueira, Sibele Nascimento de Aquino

{"title":"Lack of knowledge, understanding, and delayed attitudes towards health-seeking behavior in oral cancer patients: a qualitative pilot study.","authors":"Larissa Stefhanne Damasceno de Amorim Póvoa, Daniele Assis Souza, Francielle Silvestre Verner, Rafael Binato Junqueira, Sibele Nascimento de Aquino","doi":"10.1016/j.oooo.2024.08.024","DOIUrl":"10.1016/j.oooo.2024.08.024","url":null,"abstract":"Objective: This study aimed to explore coping strategies adopted by patients diagnosed with oral squamous cell carcinoma (OSCC) and investigate the reasons for delayed healthcare-seeking help STUDY DESIGN: Data were collected through semi-structured interviews based on the Semi-Structured Self-Regulatory Model (SRM) with participants diagnosed with advanced OSCC, between 2021 and 2023. The sample size was determined based on the saturation point. In this context, saturation refers to the point when no new issues emerge, signaling sufficient sample size. Interviews were audio-recorded, transcribed verbatim, coded, and analyzed using framework analysis.Results: The sample consisted of 15 patients, 13 male and 2 female, aged between 52 and 80 years (mean 64.5, SD ± 7.5). Four types of coping strategies causing delayed help-seeking emerged: 1) self-medication, 2) seeking medical appointments, 3) abandoning consultations (or treatment), and 4) consulting general dental practitioners. Participants believed that the disease could heal spontaneously and did not consider seeking health help immediately. Socio-economic factors and lack of knowledge on the part of healthcare professionals may have influenced the delay in the diagnosis CONCLUSION: Patients with advanced OSCC demonstrated inadequate disease awareness, oral cancer knowledge, misdiagnosis, and insufficient referrals to specialized treatments.","PeriodicalId":49010,"journal":{"name":"Oral Surgery Oral Medicine Oral Pathology Oral Radiology","volume":" ","pages":"64-72"},"PeriodicalIF":2.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142511180","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Letter to the editor regarding "Applications of artificial intelligence for surgical extraction in atomatology: a systematic review". 致编辑的信，内容涉及 "人工智能在口腔科手术取材中的应用：系统综述"。

IF 2 3区医学

Oral Surgery Oral Medicine Oral Pathology Oral Radiology Pub Date : 2025-01-01 Epub Date: 2024-10-11 DOI: 10.1016/j.oooo.2024.08.025

Pitchaipillai Sankar Ganesh, Naji Naseef Pathoor, Gopal Rajesh Kanna

引用次数: 0

The challenge of evidence-based practice in oral diagnostic sciences. 口腔诊断科学循证实践的挑战。

IF 2 3区医学

Oral Surgery Oral Medicine Oral Pathology Oral Radiology Pub Date : 2025-01-01 Epub Date: 2024-10-16 DOI: 10.1016/j.oooo.2024.10.074

Sarah G Fitzpatrick, Cesar A Migliorati

引用次数: 0

Response to comments on "applications of artificial intelligence for surgical extraction in stomatology: a systematic review". 对 "人工智能在口腔科手术取材中的应用：系统性综述 "评论的回复。

IF 2 3区医学

Oral Surgery Oral Medicine Oral Pathology Oral Radiology Pub Date : 2025-01-01 Epub Date: 2024-10-09 DOI: 10.1016/j.oooo.2024.10.001

Piaopiao Qiu, Huasheng Zhang, Rongkai Cao, Xueming Zhang

引用次数: 0

Hematolymphoid neoplasm mimicking endodontic lesions: case series and review of the literature. 模仿牙髓病变的血淋巴肿瘤：病例系列和文献综述。

IF 2 3区医学

Oral Surgery Oral Medicine Oral Pathology Oral Radiology Pub Date : 2025-01-01 Epub Date: 2024-08-05 DOI: 10.1016/j.oooo.2024.07.011

Wattawan Wongpattaraworakul, Tadkamol Krongbaramee, Emily A Lanzel, John W Hellstein, Fabricio B Teixeira

{"title":"Hematolymphoid neoplasm mimicking endodontic lesions: case series and review of the literature.","authors":"Wattawan Wongpattaraworakul, Tadkamol Krongbaramee, Emily A Lanzel, John W Hellstein, Fabricio B Teixeira","doi":"10.1016/j.oooo.2024.07.011","DOIUrl":"10.1016/j.oooo.2024.07.011","url":null,"abstract":"Hematolymphoid neoplasms originating in the periapical region of a tooth are rare occurrences. Their signs, symptoms, and radiographic findings can also mimic lesions of endodontic origin. History-taking and clinical examination provide clues to determine the possibility of a non-endodontic lesion, although the definitive diagnosis can only be rendered based on histologic examination. In our case series, we present four cases of hematolymphoid neoplasms that radiographically mimicked endodontic lesions. All the cases initially underwent endodontic treatment, but the lesions failed to resolve. In one case, the clinician suspected a diagnosis of lymphoma based on the patient's history. In the other cases, the clinicians' impression was that the lesions originated from endodontic issues. We present two cases of diffuse large B-cell lymphoma, a case of a plasma cell neoplasm, and a case of Langerhans cell histiocytosis, along with a literature review of three entities when found in the oral cavity as well as review of hematolymphoid neoplasm mimicking endodontic lesion previously reported in literature.","PeriodicalId":49010,"journal":{"name":"Oral Surgery Oral Medicine Oral Pathology Oral Radiology","volume":" ","pages":"e1-e12"},"PeriodicalIF":2.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142047404","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Diagnostic performance of ChatGPT-4.0 in histopathological description analysis of oral and maxillofacial lesions: a comparative study with pathologists.

IF 2 3区医学

Oral Surgery Oral Medicine Oral Pathology Oral Radiology Pub Date : 2024-11-28 DOI: 10.1016/j.oooo.2024.11.087

Maria Cuevas-Nunez, Valentina Ignacia Alvarez Silberberg, Maria Arregui, Bruno C Jham, Rosa Ballester-Victoria, Inessa Koptseva, María José Biosca Gómez de Tejada, Rodolfo Posada-Caez, Victor Gil Manich, Javier Bara-Casaus, Maria-Teresa Fernández-Figueras

{"title":"Diagnostic performance of ChatGPT-4.0 in histopathological description analysis of oral and maxillofacial lesions: a comparative study with pathologists.","authors":"Maria Cuevas-Nunez, Valentina Ignacia Alvarez Silberberg, Maria Arregui, Bruno C Jham, Rosa Ballester-Victoria, Inessa Koptseva, María José Biosca Gómez de Tejada, Rodolfo Posada-Caez, Victor Gil Manich, Javier Bara-Casaus, Maria-Teresa Fernández-Figueras","doi":"10.1016/j.oooo.2024.11.087","DOIUrl":"https://doi.org/10.1016/j.oooo.2024.11.087","url":null,"abstract":"Objective: To evaluate the diagnostic performance of ChatGPT-4.0 in histopathological diagnoses of oral and maxillofacial lesions and compare its performance with pathologists.Study design: A retrospective analysis of 102 histopathological descriptions was conducted. Data, including site, age and sex, were anonymized from the General University Hospital's Department of Pathology. ChatGPT-4.0 provided diagnoses, which were categorized as correct, similar, or different compared to pathologists' diagnoses. Descriptive statistics, Chi-squared tests, correlation, and regression analyses were used to assess accuracy and the influence of age and gender.Results: ChatGPT-4.0 correctly diagnosed 61 out of 102 cases, yielding an accuracy of 59.8%. The distribution of diagnostic scores did not significantly deviate from expectations (Chi-squared Statistic: 0.0, P = 1.0). A moderate negative correlation between age and diagnostic scores (r = -0.33) was observed, with age significantly predicting scores (P = .001). No significant difference was found between genders (P = .26). ChatGPT-4.0 performed worst with granuloma and inflammation cases (100% incorrect) and best with mucocele cases (93.3% correct).Conclusion: ChatGPT-4.0 shows moderate accuracy in histopathological diagnosis of oral and maxillofacial lesions, with performance varying by lesion type. Improvements are needed to enhance its clinical reliability.","PeriodicalId":49010,"journal":{"name":"Oral Surgery Oral Medicine Oral Pathology Oral Radiology","volume":" ","pages":""},"PeriodicalIF":2.0,"publicationDate":"2024-11-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142873182","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Histological assessment of extensive or unresectable central giant cell granulomas treated with denosumab - A case series.

IF 2 3区医学

Oral Surgery Oral Medicine Oral Pathology Oral Radiology Pub Date : 2024-11-28 DOI: 10.1016/j.oooo.2024.11.086

Vinod Patel, Mahesh Kumar, Andrew Schache, Keith D Hunter, Barbara Carey, Simon N Rogers, Mustansir Alibhai, Selvam Thavaraj

{"title":"Histological assessment of extensive or unresectable central giant cell granulomas treated with denosumab - A case series.","authors":"Vinod Patel, Mahesh Kumar, Andrew Schache, Keith D Hunter, Barbara Carey, Simon N Rogers, Mustansir Alibhai, Selvam Thavaraj","doi":"10.1016/j.oooo.2024.11.086","DOIUrl":"https://doi.org/10.1016/j.oooo.2024.11.086","url":null,"abstract":"Objective: The management of large central giant cell granuloma (CGCG) can pose a significant surgical challenge. In such circumstances, the use of denosumab has been proposed with the literature reporting varying degrees of success. Histopathological assessment of CGCG post-denosumab treatment remains unknown. The current case series aims to address this lack of information and supplement the literature and the debate with evidence.Study design: The current case series is a retrospective review of historic cases accumulated from 3 different hospitals. Patients treated with denosumab for large or unresectable GCGC who subsequently underwent either surgical debulk or resection post drug treatment with histological tissue for assessment were included.Results: A total of 4 patients were included in this study. All cases showed radiographic response. However histological assessment identified giant cells in 3 of the 4 cases, 2 of which showed clinical recurrence. All cases demonstrated irregular woven bone formation toward the periphery of the lesion suggesting partial response.Conclusions: The current case series provides some insight regarding the response of CGCG to denosumab and preliminary histopathological information toward the ongoing debate regarding the medical management of CGCG. (Oral Surg Oral Med Oral Pathol Oral Radiol YEAR;VOL:page range).","PeriodicalId":49010,"journal":{"name":"Oral Surgery Oral Medicine Oral Pathology Oral Radiology","volume":" ","pages":""},"PeriodicalIF":2.0,"publicationDate":"2024-11-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142873184","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Epigenetic regulation of HOXA3 and its impact on oral squamous cell carcinoma progression.

IF 2 3区医学

Oral Surgery Oral Medicine Oral Pathology Oral Radiology Pub Date : 2024-11-22 DOI: 10.1016/j.oooo.2024.11.088

Kanaka Sai Ram Padam, Dhanraj Salur Basavarajappa, Naveena A N Kumar, Srikanth Gadicherla, Sanjiban Chakrabarty, Keith D Hunter, Raghu Radhakrishnan

{"title":"Epigenetic regulation of HOXA3 and its impact on oral squamous cell carcinoma progression.","authors":"Kanaka Sai Ram Padam, Dhanraj Salur Basavarajappa, Naveena A N Kumar, Srikanth Gadicherla, Sanjiban Chakrabarty, Keith D Hunter, Raghu Radhakrishnan","doi":"10.1016/j.oooo.2024.11.088","DOIUrl":"https://doi.org/10.1016/j.oooo.2024.11.088","url":null,"abstract":"Objective: The role of homeobox A3 (HOXA3) in cancer progression is gaining prominence, however, to date, no studies have investigated its regulatory function in oral cancer. In this study, we explored the role of HOXA3 through epigenetic mechanisms.Methods: Clinical samples were collected from 25 potentially malignant oral lesions and 50 oral squamous cell carcinoma (OSCC) patients, categorized into low-stage and high-stage tumors. The promoter activity of HOXA3 was determined through cloning and luciferase assays. CpG methylation patterns across the gene were identified using methyl-capture sequencing. Gene expression was analyzed using RT‒qPCR. The Survminer R package was used to assess the clinical significance of 3' UTR methylation associated with overall survival. RNA‒RNA interactions were analyzed using RNAInter and TargetScan v8.0.Results: HOXA3 expression was upregulated in dysplasia and downregulated in advanced cancer stages, showing an inverse correlation with promoter methylation, suggesting epigenetic regulation by DNA methylation. Hypermethylation of the 3' UTR was associated with poor overall survival in advanced stages. Long noncoding RNAs and microRNAs may post-transcriptionally modulate HOXA3 in oral carcinogenesis.Conclusion: CpG-specific hypermethylation in the 3' UTR may serve as a potential biomarker in OSCC.","PeriodicalId":49010,"journal":{"name":"Oral Surgery Oral Medicine Oral Pathology Oral Radiology","volume":" ","pages":""},"PeriodicalIF":2.0,"publicationDate":"2024-11-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142808056","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Destructive mandibular mass in a 60-year-old female.

IF 2 3区医学

Oral Surgery Oral Medicine Oral Pathology Oral Radiology Pub Date : 2024-11-19 DOI: 10.1016/j.oooo.2024.11.083

Joshua Allen, Fawaz Alotaibi, Yousef Alshamrani, Abdulrahman Hesham, Ashley Flowers, D David Kim, Victoria Woo

引用次数: 0