Oral Surgery Oral Medicine Oral Pathology Oral Radiology最新文献

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Gingival enlargement in a child with difficulty walking. 行走困难儿童的牙龈肿大。
IF 1.9 3区 医学
Oral Surgery Oral Medicine Oral Pathology Oral Radiology Pub Date : 2026-04-14 DOI: 10.1016/j.oooo.2026.04.001
Sarah Wan-Lin Lim, Yu Jie Chin, Shani Ann Mani
{"title":"Gingival enlargement in a child with difficulty walking.","authors":"Sarah Wan-Lin Lim, Yu Jie Chin, Shani Ann Mani","doi":"10.1016/j.oooo.2026.04.001","DOIUrl":"https://doi.org/10.1016/j.oooo.2026.04.001","url":null,"abstract":"","PeriodicalId":49010,"journal":{"name":"Oral Surgery Oral Medicine Oral Pathology Oral Radiology","volume":" ","pages":""},"PeriodicalIF":1.9,"publicationDate":"2026-04-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147857196","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Introducing Dr Andres Pinto as the journal's new oral medicine section editor. 介绍安德烈斯·平托博士为该杂志新的口腔医学部分编辑。
IF 1.9 3区 医学
Oral Surgery Oral Medicine Oral Pathology Oral Radiology Pub Date : 2026-03-29 DOI: 10.1016/j.oooo.2026.03.010
Mark W Lingen
{"title":"Introducing Dr Andres Pinto as the journal's new oral medicine section editor.","authors":"Mark W Lingen","doi":"10.1016/j.oooo.2026.03.010","DOIUrl":"https://doi.org/10.1016/j.oooo.2026.03.010","url":null,"abstract":"","PeriodicalId":49010,"journal":{"name":"Oral Surgery Oral Medicine Oral Pathology Oral Radiology","volume":" ","pages":""},"PeriodicalIF":1.9,"publicationDate":"2026-03-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147786695","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Epidemiological analysis of odontogenic cysts and tumors: a 10-year retrospective study based on the 2022 WHO classification. 牙源性囊肿和肿瘤的流行病学分析:基于2022年WHO分类的10年回顾性研究
IF 1.9 3区 医学
Oral Surgery Oral Medicine Oral Pathology Oral Radiology Pub Date : 2026-03-26 DOI: 10.1016/j.oooo.2026.03.009
Omer Faruk Gurbuz, Dilek Menziletoglu, Bozkurt Kubilay Isık, Alparslan Esen
{"title":"Epidemiological analysis of odontogenic cysts and tumors: a 10-year retrospective study based on the 2022 WHO classification.","authors":"Omer Faruk Gurbuz, Dilek Menziletoglu, Bozkurt Kubilay Isık, Alparslan Esen","doi":"10.1016/j.oooo.2026.03.009","DOIUrl":"https://doi.org/10.1016/j.oooo.2026.03.009","url":null,"abstract":"<p><strong>Objective: </strong>This study aims to evaluate the epidemiological and clinico-pathological characteristics of odontogenic cysts and tumors in a Turkish subpopulation based on the 2022 WHO classification.</p><p><strong>Study design: </strong>A retrospective analysis was conducted on 1050 patients treated at a regional tertiary center over a 10-year period (2015-2025). Data regarding age, sex, histopathological diagnosis, and anatomical localization were statistically evaluated.</p><p><strong>Results: </strong>Of the 1050 cases, 94.2% (n = 989) were odontogenic cysts and 5.8% (n = 61) were odontogenic tumors. The mean age of the cohort was 41.90 ± 16.75 years, with cysts appearing in significantly older patients compared to tumors (p < .001). Odontogenic cysts showed a male predominance (57.5%), while tumors occurred more frequently in females (65.6%). The most frequent lesions were radicular cysts (76%) and odontomas (68.9%). The posterior mandible was the primary anatomical site for both categories (44.4% for cysts; 36.1% for tumors).</p><p><strong>Conclusion: </strong>While the findings generally align with the global literature and the 2022 WHO criteria, the high prevalence of inflammatory cysts and specific demographic variations underscore the influence of regional dynamics and access to dental care.</p>","PeriodicalId":49010,"journal":{"name":"Oral Surgery Oral Medicine Oral Pathology Oral Radiology","volume":" ","pages":""},"PeriodicalIF":1.9,"publicationDate":"2026-03-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147786319","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effectiveness of kinesiologic tape in the management of postoperative trismus, discomfort, and edema in mandibular fractures: a randomized controlled trial. 运动学胶带在治疗下颌骨折术后牙关、不适和水肿中的有效性:一项随机对照试验。
IF 1.9 3区 医学
Oral Surgery Oral Medicine Oral Pathology Oral Radiology Pub Date : 2026-03-21 DOI: 10.1016/j.oooo.2026.03.004
Akash Mandal, Sanjay S Rao, Rupinder Kaur
{"title":"Effectiveness of kinesiologic tape in the management of postoperative trismus, discomfort, and edema in mandibular fractures: a randomized controlled trial.","authors":"Akash Mandal, Sanjay S Rao, Rupinder Kaur","doi":"10.1016/j.oooo.2026.03.004","DOIUrl":"https://doi.org/10.1016/j.oooo.2026.03.004","url":null,"abstract":"<p><strong>Objective: </strong>This study compared kinesiologic taping (KT) with conventional elastic adhesive bandaging in managing postoperative morbidity following open reduction and internal fixation.</p><p><strong>Study design: </strong>In this prospective, randomized controlled trial conducted at KLE Dr Prabhakar Kore Hospital, 26 patients with unilateral mandibular fractures were allocated into two groups: Group 1 received an elastic adhesive bandage (n = 13) and Group 2 used KT (n = 13). Pain (Visual Analog Scale), facial swelling (standardized linear measurements), and maximum interincisal distance were recorded at baseline and on postoperative Days 2 and 5. Data were analyzed using repeated measures ANOVA and independent t tests (p < .05).</p><p><strong>Results: </strong>The KT group showed significantly lower pain scores and reduced facial edema at Days 2 and 5 compared with controls (P < .05). Trismus improved in both groups without significant intergroup differences. No adverse effects were observed.</p><p><strong>Conclusions: </strong>KT is a safe and effective adjunct for reducing early postoperative pain and edema after mandibular fracture fixation.</p>","PeriodicalId":49010,"journal":{"name":"Oral Surgery Oral Medicine Oral Pathology Oral Radiology","volume":" ","pages":""},"PeriodicalIF":1.9,"publicationDate":"2026-03-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147786303","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Letter to the editor on "Cannabis-related facial trauma: a 10-year review of facial trauma in Victoria, Australia". 致编辑关于“大麻相关面部创伤:澳大利亚维多利亚州面部创伤十年回顾”的信。
IF 1.9 3区 医学
Oral Surgery Oral Medicine Oral Pathology Oral Radiology Pub Date : 2026-03-20 DOI: 10.1016/j.oooo.2026.02.022
Vaibhav Sahni
{"title":"Letter to the editor on \"Cannabis-related facial trauma: a 10-year review of facial trauma in Victoria, Australia\".","authors":"Vaibhav Sahni","doi":"10.1016/j.oooo.2026.02.022","DOIUrl":"https://doi.org/10.1016/j.oooo.2026.02.022","url":null,"abstract":"","PeriodicalId":49010,"journal":{"name":"Oral Surgery Oral Medicine Oral Pathology Oral Radiology","volume":" ","pages":""},"PeriodicalIF":1.9,"publicationDate":"2026-03-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147786739","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Deep learning approach to identify histological features associated with lymph node metastasis following primary tumor excision in patients with tongue squamous cell carcinoma. 用深度学习方法识别舌鳞癌原发肿瘤切除后淋巴结转移的组织学特征。
IF 1.9 3区 医学
Oral Surgery Oral Medicine Oral Pathology Oral Radiology Pub Date : 2026-03-19 DOI: 10.1016/j.oooo.2026.03.006
Kohei Kawamura, Shin-Ichiro Hiraoka, Chonho Lee, Kaori Ohya, Ryo Akiyama, Shuji Uchida, Yutaka Itakura, Satoru Toyosawa, Susumu Tanaka
{"title":"Deep learning approach to identify histological features associated with lymph node metastasis following primary tumor excision in patients with tongue squamous cell carcinoma.","authors":"Kohei Kawamura, Shin-Ichiro Hiraoka, Chonho Lee, Kaori Ohya, Ryo Akiyama, Shuji Uchida, Yutaka Itakura, Satoru Toyosawa, Susumu Tanaka","doi":"10.1016/j.oooo.2026.03.006","DOIUrl":"https://doi.org/10.1016/j.oooo.2026.03.006","url":null,"abstract":"<p><strong>Objective: </strong>To assess whether a semi-automated deep learning (DL) detector that quantifies poorly differentiated nests on hematoxylin-eosin (HE) sections is associated with cervical lymph node (LN) metastasis in tongue squamous cell carcinoma (SCC), and to explore postoperative risk stratification in clinically node-negative early-stage disease.</p><p><strong>Study design: </strong>Retrospective single-center study of 115 tongue SCC patients (1998-2016) with ≥5-year follow-up. A Faster region-based convolutional neural network detector quantified poorly differentiated nests at the invasive front. Mean nest counts were compared between LN-positive and LN-negative cases and evaluated by receiver operating characteristic (ROC) analysis. The ROC cut-off was explored in an independent cohort of 20 cT1-T2 cN0 cases without elective neck dissection.</p><p><strong>Results: </strong>LN-positive cases had higher poorly differentiated nest counts than LN-negative cases. The mean count yielded an area under the curve of 0.67 for discriminating cervical LN metastasis confirmed at initial treatment or during follow-up. In the independent cohort, the cut-off (≥3.6 nests per case) showed 72.7% sensitivity and 55.6% specificity, with higher sensitivity but lower specificity than Yamamoto-Kohama mode of invasion.</p><p><strong>Conclusions: </strong>DL-based nest quantification on routine HE sections may aid postoperative risk stratification for cervical LN metastasis in tongue SCC.</p>","PeriodicalId":49010,"journal":{"name":"Oral Surgery Oral Medicine Oral Pathology Oral Radiology","volume":" ","pages":""},"PeriodicalIF":1.9,"publicationDate":"2026-03-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147678041","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Global HPV genotype distribution and coinfections in oropharyngeal squamous cell carcinoma: systematic review and meta-analysis. 口咽鳞状细胞癌的全球HPV基因型分布和共感染:系统回顾和荟萃分析。
IF 1.9 3区 医学
Oral Surgery Oral Medicine Oral Pathology Oral Radiology Pub Date : 2026-03-19 DOI: 10.1016/j.oooo.2026.03.005
Isaac Santos Araújo, Ricardo Anderson de Oliveira Vasconcelos, João Paulo Gonçalves de Paiva, Victor Samuel de Almeida Lopes, Alan Roger Santos-Silva, Márcio Ajudarte Lopes, Fabio de Abreu Alves, Ciro Dantas Soares
{"title":"Global HPV genotype distribution and coinfections in oropharyngeal squamous cell carcinoma: systematic review and meta-analysis.","authors":"Isaac Santos Araújo, Ricardo Anderson de Oliveira Vasconcelos, João Paulo Gonçalves de Paiva, Victor Samuel de Almeida Lopes, Alan Roger Santos-Silva, Márcio Ajudarte Lopes, Fabio de Abreu Alves, Ciro Dantas Soares","doi":"10.1016/j.oooo.2026.03.005","DOIUrl":"https://doi.org/10.1016/j.oooo.2026.03.005","url":null,"abstract":"<p><strong>Purpose: </strong>This study systematically reviewed and meta-analyzed the global prevalence and genotype distribution of human papillomavirus (HPV) in oropharyngeal squamous cell carcinoma (OPSCC).</p><p><strong>Materials and methods: </strong>Six databases and gray literature were searched and identified studies of biopsy-confirmed OPSCC with HPV detected by molecular methods. A meta-analysis was performed using random-effects generalized linear mixed models to calculate pooled prevalence estimates with 95% confidence intervals. Temporal trends were explored by meta-regression, and risk of bias was assessed using Joanna Briggs Institute tools.</p><p><strong>Results: </strong>A total of 183 studies with 34,627 OPSCC patients from 35 countries were included; of these, 17,443 were HPV-positive with available genotyping data. The meta-analysis showed that HPV16 was the predominant genotype (92.5% of single infections), followed by HPV33 (3.3%), HPV18 (2.8%), and HPV35 (2.8%). Coinfections were rare (1.3%), most frequently involving HPV16 with other high-risk genotypes such as HPV18, 33, and 31. Meta-regression revealed a temporal decline in HPV16 concurrent with a rise in non-HPV16 genotypes.</p><p><strong>Conclusion: </strong>HPV16 remains the predominant genotype in OPSCC worldwide, the contribution of other oncogenic types is increasing. These findings reinforce the importance of HPV genotyping to support surveillance and vaccination strategies and to improve understanding of HPV-driven OPSCC tumor biology.</p>","PeriodicalId":49010,"journal":{"name":"Oral Surgery Oral Medicine Oral Pathology Oral Radiology","volume":" ","pages":""},"PeriodicalIF":1.9,"publicationDate":"2026-03-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147678047","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Gingival lymphangioma circumscriptum in children: a misdiagnosed gingival lesion-insights from a multicenter case series. 儿童牙龈边缘淋巴管瘤:一个误诊的牙龈病变-来自多中心病例系列的见解。
IF 1.9 3区 医学
Oral Surgery Oral Medicine Oral Pathology Oral Radiology Pub Date : 2026-03-18 DOI: 10.1016/j.oooo.2026.03.007
Gerardo Gilligan, Andrea Romero, René Jara, Benjamin Martinez-Rondanelli
{"title":"Gingival lymphangioma circumscriptum in children: a misdiagnosed gingival lesion-insights from a multicenter case series.","authors":"Gerardo Gilligan, Andrea Romero, René Jara, Benjamin Martinez-Rondanelli","doi":"10.1016/j.oooo.2026.03.007","DOIUrl":"https://doi.org/10.1016/j.oooo.2026.03.007","url":null,"abstract":"<p><p>Lymphatic malformations are uncommon congenital anomalies resulting from abnormal lymphatic development and are considered hamartomatous rather than neoplastic lesions. Within the oral cavity, gingival involvement may pose a diagnostic challenge due to its clinical resemblance to common reactive or inflammatory conditions. This study reports four new cases of gingival lymphatic malformations diagnosed across 3 oral pathology centers in Argentina and Chile. Clinically, the lesions presented as small, localized gingival enlargements with a vesicular or lobulated surface, sometimes displaying translucent, yellowish, or violaceous areas, predominantly affecting interdental papillae. In all cases, the lesions were not clinically suspected to represent lymphatic malformations and were initially considered reactive gingival conditions. Histopathological examination consistently revealed dilated lymphatic vessels predominantly located within the superficial lamina propria, lined by flattened endothelial cells and containing lymphatic fluid with occasional erythrocytes, accompanied by a mild inflammatory infiltrate-findings consistent with solitary superficial microcystic lymphatic malformations. All cases were managed by complete surgical excision, resulting in satisfactory healing and no evidence of recurrence during follow-up. These cases expand the limited literature on gingival lymphatic malformations and emphasize the importance of considering this entity in the differential diagnosis of localized gingival lesions. Accurate recognition and complete removal are essential to ensure optimal clinical outcomes.</p>","PeriodicalId":49010,"journal":{"name":"Oral Surgery Oral Medicine Oral Pathology Oral Radiology","volume":" ","pages":""},"PeriodicalIF":1.9,"publicationDate":"2026-03-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147624484","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Evaluation of bone shells for 3D bone reconstruction of atrophic posterior mandible. A Randomized controlled clinical trial. 骨壳对萎缩后下颌骨三维骨重建的评价。随机对照临床试验。
IF 1.9 3区 医学
Oral Surgery Oral Medicine Oral Pathology Oral Radiology Pub Date : 2026-03-13 DOI: 10.1016/j.oooo.2026.02.020
Rami Richa, Nada M H Fahmy, Hagar Sherif Abdel Fattah, Hani Arakji
{"title":"Evaluation of bone shells for 3D bone reconstruction of atrophic posterior mandible. A Randomized controlled clinical trial.","authors":"Rami Richa, Nada M H Fahmy, Hagar Sherif Abdel Fattah, Hani Arakji","doi":"10.1016/j.oooo.2026.02.020","DOIUrl":"https://doi.org/10.1016/j.oooo.2026.02.020","url":null,"abstract":"<p><strong>Objective: </strong>. To evaluate the efficiency of using the bone shells combined with xenograft + PRF for Three-dimensional (3D) ridge reconstruction of the posterior atrophic mandible.</p><p><strong>Materials and methods: </strong>. This study was a randomized controlled trial on patients with posterior mandibular edentulism associated with the presence of vertical bone deficiency. 3D bone augmentation was performed on 13 randomly allocated patients with guided bone regeneration (control group), where the study group was composed of 13 patients who received the bone-modified shells technique. Implants were placed 6 months after bone augmentation for both groups. Clinically, healing, pain, and implant stability were evaluated. In addition to the radiographical evaluation of vertical bone height. The nature and maturation of augmented bone were evaluated histologically.</p><p><strong>Results: </strong>The early follow-up showed no statistically significant difference between the 2 groups in terms of wound dehiscence. Statistically significant difference in pain in the early healing phase in favor to control group. No statistical difference between the 2 groups in terms of bone quantity after 6months at the implant placement.</p><p><strong>Conclusion: </strong>The favorable clinical outcomes indicate that the combination of xenograft with an autogenous cortical shell may represent a viable option for three-dimensional bone augmentation with reduced donor-site morbidity. The cortical shell thickness used was sufficient to maintain the augmented alveolar contour and structural integrity, allowing predictable containment and uninterrupted incorporation of the xenograft coagulum.</p>","PeriodicalId":49010,"journal":{"name":"Oral Surgery Oral Medicine Oral Pathology Oral Radiology","volume":" ","pages":""},"PeriodicalIF":1.9,"publicationDate":"2026-03-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147786672","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Investigating the effectiveness of ibuprofen mucoadhesive gel on minor recurrent aphthous stomatitis: a randomized double-blind clinical trial. 研究布洛芬黏合剂凝胶治疗轻微复发性口腔溃疡的疗效:随机双盲临床试验。
IF 1.9 3区 医学
Oral Surgery Oral Medicine Oral Pathology Oral Radiology Pub Date : 2026-03-13 DOI: 10.1016/j.oooo.2026.02.018
Tahereh Molania, Majid Saeedi, Anahita Lotfizadeh, Reza Negarandeh, Abolfazl Hosseinnataj, Azam Haddadi, Abbas Abbasi, Maede Salehi
{"title":"Investigating the effectiveness of ibuprofen mucoadhesive gel on minor recurrent aphthous stomatitis: a randomized double-blind clinical trial.","authors":"Tahereh Molania, Majid Saeedi, Anahita Lotfizadeh, Reza Negarandeh, Abolfazl Hosseinnataj, Azam Haddadi, Abbas Abbasi, Maede Salehi","doi":"10.1016/j.oooo.2026.02.018","DOIUrl":"https://doi.org/10.1016/j.oooo.2026.02.018","url":null,"abstract":"<p><strong>Objective: </strong>Recurrent aphthous stomatitis (RAS) is the most common form of oral mucosal lesions. This preliminary study investigated the effectiveness of ibuprofen mucoadhesive gel on minor aphthous lesions.</p><p><strong>Study design: </strong>In this randomized double-blind clinical trial, 44 participants, 22 in each intervention and control groups, used mucoadhesive gels 6 times a day. On days 0 (baseline), 3, 5, and 7, the lesion diameter was measured. Pain intensity was recorded using a visual numerical scale (VNS). Independent t-test, Friedman, generalized estimating equation (GEE), Mann-Whitney, and Chi-square tests were used to analyze data. Data analysis was performed using SPSS 22.</p><p><strong>Results: </strong>Comparison of the difference in mean lesion diameter between the 2 groups on measurement days and the baseline showed significant results (P < .05). The reduction in lesion diameter was greater in the intervention group. The mean pain intensity of the intervention group on days 4 (1.31 ± 2.56), 5 (0.91 ± 1.00), and 6 (0.69 ± 0.39) was significantly lower than that of the control group on days 4 (3.91 ± 2.36), 5 (2.61 ± 2.36), and 6 (1.52 ± 1.60) (P < .05).</p><p><strong>Conclusion: </strong>The ibuprofen mucoadhesive gel resulted in a greater reduction in lesion diameter when comparing the results with the baseline and compared to the control group. Its analgesic effect was confined to days 4 to 6 of the study.</p><p><strong>Clinical trial registration number: </strong>Iranian Registry of Clinical Trials (IRCT20241208063987N1).</p>","PeriodicalId":49010,"journal":{"name":"Oral Surgery Oral Medicine Oral Pathology Oral Radiology","volume":" ","pages":""},"PeriodicalIF":1.9,"publicationDate":"2026-03-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147786747","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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