Oral Surgery Oral Medicine Oral Pathology Oral Radiology最新文献

Tyrosine kinase inhibitor as a cause of palatal pigmentation

IF 2 3区医学

Oral Surgery Oral Medicine Oral Pathology Oral Radiology Pub Date : 2025-03-14 DOI: 10.1016/j.oooo.2025.01.084

André Luis Santana de Freitas, Marcelo Sperandio, Rosane Rezende de Souza Giuliani, Alvaro Luiz Mendonça Pinheiro Barbosa, Tiago Tavares, Andresa Borges Soares, Fabricio Passador-Santos

引用次数: 0

Antimicrobial photodynamic therapy in the treatment of oral lesions: experience report and clinical protocol

IF 2 3区医学

Oral Surgery Oral Medicine Oral Pathology Oral Radiology Pub Date : 2025-03-14 DOI: 10.1016/j.oooo.2025.01.059

Giovanna Meneses, Maria Paula Siqueira de Melo Peres, Juliana Bertoldi Franco

{"title":"Antimicrobial photodynamic therapy in the treatment of oral lesions: experience report and clinical protocol","authors":"Giovanna Meneses, Maria Paula Siqueira de Melo Peres, Juliana Bertoldi Franco","doi":"10.1016/j.oooo.2025.01.059","DOIUrl":"10.1016/j.oooo.2025.01.059","url":null,"abstract":"<div><div>Antimicrobial photodynamic therapy (aPDT) is based on the application of a photosensitizing agent on the injured tissue followed by low-level laser therapy (LLLT) emission on the region. The interaction generates free radicals and oxidation of the plasma membrane of microorganisms, providing antimicrobia, antiviral and antifungal activity without harming healthy host cells. Is considered a noninvasive, local, painless procedure, which has the advantage of tissue biostimulating, helping to reduce the administration of systemic medications in immunosuppressed patients. The photosensitizing agent (methylene blue 0.01%) was applied over all lesions and, after 5 minutes, LLLT was used at 660 nm, on contact mode, point by point, with 100 mW, 178 J/cm 2, 6J, and 60s per point, with sessions every 24 hours depending on clinical evolution. Widely used in the treatment of oral lesions in adult and pediatric patients, in herpetic lesions, candidiasis, Paracoccidioidomycosis, osteonecrosis of the jaws, and osteoradionecrosis, with success.</div></div>","PeriodicalId":49010,"journal":{"name":"Oral Surgery Oral Medicine Oral Pathology Oral Radiology","volume":"139 5","pages":"Page e11"},"PeriodicalIF":2.0,"publicationDate":"2025-03-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143619939","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Nevoid basal cell carcinoma syndrome: clinical presentation, diagnosis, and management in a pediatric patient

IF 2 3区医学

Oral Surgery Oral Medicine Oral Pathology Oral Radiology Pub Date : 2025-03-14 DOI: 10.1016/j.oooo.2025.01.037

Fabiana Ferreira Alves, Ana Claudia Garcia Rosa, Basilio de Almeida Milani

{"title":"Nevoid basal cell carcinoma syndrome: clinical presentation, diagnosis, and management in a pediatric patient","authors":"Fabiana Ferreira Alves, Ana Claudia Garcia Rosa, Basilio de Almeida Milani","doi":"10.1016/j.oooo.2025.01.037","DOIUrl":"10.1016/j.oooo.2025.01.037","url":null,"abstract":"<div><div>Nevoid Basal Cell Carcinoma Syndrome (NBCCS) is a hereditary condition caused by mutations in the PTCH gene, leading to multiple basal cell carcinomas on the skin, odontogenic keratocysts, intracranial calcifications, and anomalies of the ribs and vertebrae. A 10-year-old girl presented with maxillary and mandibular unicystic radiolucent lesions, a family history of cutaneous tumors, and physical characteristics such as palmoplantar depressions, hypertelorism, and bifid ribs. Incisional biopsy of the maxillary lesions revealed cysts lined with keratinized odontogenic epithelium with palisaded basal layer cells, diagnosed as keratocysts. Based on clinical features and complementary exams, the final diagnosis was NBCCS. Treatment involved the enucleation of keratocysts and peripheral ostectomy. The patient is under constant follow-up. Genetic counseling is crucial in NBCCS. Due to its impacts on various organs, treatment requires a multidisciplinary team and continuous monitoring. Early diagnosis is essential for screening neoplasms and reducing the morbidity associated with basal cell carcinomas.</div></div>","PeriodicalId":49010,"journal":{"name":"Oral Surgery Oral Medicine Oral Pathology Oral Radiology","volume":"139 5","pages":"Page e7"},"PeriodicalIF":2.0,"publicationDate":"2025-03-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143619991","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Oral manifestations of congenital syphilis: a case report

IF 2 3区医学

Oral Surgery Oral Medicine Oral Pathology Oral Radiology Pub Date : 2025-03-14 DOI: 10.1016/j.oooo.2025.01.043

Paula Joaquim Bratfisch Lins, Fabiana Martins e Martins de Oliveira, Marina Gallottini

{"title":"Oral manifestations of congenital syphilis: a case report","authors":"Paula Joaquim Bratfisch Lins, Fabiana Martins e Martins de Oliveira, Marina Gallottini","doi":"10.1016/j.oooo.2025.01.043","DOIUrl":"10.1016/j.oooo.2025.01.043","url":null,"abstract":"<div><div>A 4-year-old girl presented for a dental appointment at the Special Care Dentistry Center, brought by her paternal grandmother complaining of dental hypersensitivity. The patient was born prematurely, with low birth weight, and congenital syphilis. She presents with deafness, prominent frontal bossing, and so far, has shown normal neuro-motor development. She has primary dentition with generalized enamel structure alterations, characterized by yellowish teeth, hypoplastic teeth, enamel prominences, and anterior open bite. Radiographic images and dental history revealed the congenital absence of mandibular second premolars and notched incisors. Interstitial keratitis, which completes the Hutchinson's triad, has not been investigated yet. The treatment plan includes preventive care, photobiomodulation protocol for dentin hypersensitivity, molar sealings, direct resin restorations for aesthetic purposes, and occlusal follow-up of permanent dentition. Congenital syphilis is a preventable disease, and its presence reflects a failure of the prenatal care delivery system, as well as syphilis control programs.</div></div>","PeriodicalId":49010,"journal":{"name":"Oral Surgery Oral Medicine Oral Pathology Oral Radiology","volume":"139 5","pages":"Page e8"},"PeriodicalIF":2.0,"publicationDate":"2025-03-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143619997","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Medication associated osteonecrosis: exploring the efficacy of sonodynamic therapy in a series of cases

IF 2 3区医学

Oral Surgery Oral Medicine Oral Pathology Oral Radiology Pub Date : 2025-03-14 DOI: 10.1016/j.oooo.2025.01.026

Larissa Araujo Agatti, Paulo de Camargo Moraes, Aguinaldo Garcez, Daniela Prata Tacchelli, Marcelo Sperandio, Victor Montalli

{"title":"Medication associated osteonecrosis: exploring the efficacy of sonodynamic therapy in a series of cases","authors":"Larissa Araujo Agatti, Paulo de Camargo Moraes, Aguinaldo Garcez, Daniela Prata Tacchelli, Marcelo Sperandio, Victor Montalli","doi":"10.1016/j.oooo.2025.01.026","DOIUrl":"10.1016/j.oooo.2025.01.026","url":null,"abstract":"<div><div>This study explores Sonodynamic Therapy (SDT) for treating oral osteonecrosis in 6 patients, after cancer therapies including bisphosphonates, monoclonal antibodies, and corticosteroids. These treatments previously led to complications like pain, recurrent infections, and reduced quality of life, affecting dietary habits and social interactions due to the odor of lesions. Osteonecrosis, linked to medication, diminishes bone blood supply either temporarily or permanently. Comprehensive patient evaluations, including medication histories and clinical imaging, preceded SDT treatment. SDT, an innovative approach, uses low-frequency, high-intensity ultrasound to activate sonosensitizers, producing reactive oxygen species (ROS) for noninvasive infection control. Remarkable improvements were observed in all patients, demonstrating SDTs broader clinical utility, especially in resource-limited settings. This research underscores SDTs efficacy in improving osteonecrosis patients’ conditions, suggesting the need for further investigation and potential adoption in clinical practices. The study indicates SDTs promise to enhance quality of life and support its broader clinical application and research.</div></div>","PeriodicalId":49010,"journal":{"name":"Oral Surgery Oral Medicine Oral Pathology Oral Radiology","volume":"139 5","pages":"Page e5"},"PeriodicalIF":2.0,"publicationDate":"2025-03-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143620127","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Tongue neuroma in a pediatric patient

IF 2 3区医学

Oral Surgery Oral Medicine Oral Pathology Oral Radiology Pub Date : 2025-03-14 DOI: 10.1016/j.oooo.2025.01.052

Mariana Israel Rocha, Karine Duarte da Silva, Juliani Santana de Oliveira, Kelly Machado de Andrade e Reyes, Ingrid Akemi Morita Kataguiri, Tatiane Marega, Silvana Ribeiro Roda

引用次数: 0

Management of odontogenic myxoma and carcinoma cases for oral rehabilitation

IF 2 3区医学

Oral Surgery Oral Medicine Oral Pathology Oral Radiology Pub Date : 2025-03-14 DOI: 10.1016/j.oooo.2025.01.055

Leonardo Das Neves Souza, Daniel Yuydi Kawakami, Gisele Lie Fukuoka, Carina Domaneschi, Érico Castaldin Fraga Moreira, Rodrigo Diniz Gomes, Roberto Chaib Stegun

{"title":"Management of odontogenic myxoma and carcinoma cases for oral rehabilitation","authors":"Leonardo Das Neves Souza, Daniel Yuydi Kawakami, Gisele Lie Fukuoka, Carina Domaneschi, Érico Castaldin Fraga Moreira, Rodrigo Diniz Gomes, Roberto Chaib Stegun","doi":"10.1016/j.oooo.2025.01.055","DOIUrl":"10.1016/j.oooo.2025.01.055","url":null,"abstract":"<div><div>This study describes the rehabilitation of 2 patients, one with mandibular odontogenic myxoma and the other with epithelial-myoepithelial carcinoma (EMC) of the salivary gland. The first patient faced complications in speech, eating, and aesthetics after a mandibular resection performed in 2012. The second underwent chemotherapy and radiotherapy treatment in 2021 and began oral rehabilitation in 2022. The patients were submitted to clinical and radiographic exams, revealing that both presented loss of Vertical Dimension of Occlusion (VDO). Additionally, the patient with myxoma lost the alveolar ridge due to surgical treatment and the rehabilitation was done by using conventional removable partial dentures (RPD). The patient with EMC had an absence of 11 teeth, and the rehabilitation was done using thermoplastic resin RPD. Both patients are followed up twice a year. This study highlights that treatment with RPD provides a functional and cost-effective option for oral structure injuries.</div></div>","PeriodicalId":49010,"journal":{"name":"Oral Surgery Oral Medicine Oral Pathology Oral Radiology","volume":"139 5","pages":"Page e10"},"PeriodicalIF":2.0,"publicationDate":"2025-03-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143619935","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Metastatic adenocarcinoma: a case report of multiple primary tumors in the oral cavity

IF 2 3区医学

Oral Surgery Oral Medicine Oral Pathology Oral Radiology Pub Date : 2025-03-14 DOI: 10.1016/j.oooo.2025.01.058

Juliana Meneses Montalvão Costa, Liliana Wolf Braun, Thais Lins Soares Leite, Luis Afonso Tochetto, Marco Antonio Trevizani Martins, Vinicius Coelho Carrard, Manoela Domingues Martins

{"title":"Metastatic adenocarcinoma: a case report of multiple primary tumors in the oral cavity","authors":"Juliana Meneses Montalvão Costa, Liliana Wolf Braun, Thais Lins Soares Leite, Luis Afonso Tochetto, Marco Antonio Trevizani Martins, Vinicius Coelho Carrard, Manoela Domingues Martins","doi":"10.1016/j.oooo.2025.01.058","DOIUrl":"10.1016/j.oooo.2025.01.058","url":null,"abstract":"<div><div>A 59-year-old male patient was referred to the oral medicine department because of persistent sialorrhea and dysphagia resulting from squamous cell carcinoma of the esophagus that was treated with radiotherapy in 2021. The patient was taking omeprazole 20 mg daily and denied smoking or alcohol consumption regularly. During evaluation, a hard asymptomatic nodule was identified on the right lateral border of the patient's tongue. An incisional biopsy revealed adenosquamous carcinoma, and the patient underwent partial glossectomy with supraomohyoid neck dissection. Two months later, the patient developed a hard submucosal nodule on the lower lip, which was diagnosed as conventional polymorphic adenocarcinoma. Metastatic lesions of polymorphic adenocarcinoma were also detected in the right temporal region, eyebrow, and upper and lower lips. Palliative chemotherapy was recommended, consisting of 8 cycles of carboplatin AUC 5 and paclitaxel 175 mg/m<sup>2</sup> administered every 21 days, followed by the FOLFOX (leucovorin, fluorouracil, and oxaliplatin) second-line chemotherapy protocol.</div></div>","PeriodicalId":49010,"journal":{"name":"Oral Surgery Oral Medicine Oral Pathology Oral Radiology","volume":"139 5","pages":"Page e11"},"PeriodicalIF":2.0,"publicationDate":"2025-03-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143619938","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Adenoid ameloblastoma with dentinoid: a case report

IF 2 3区医学

Oral Surgery Oral Medicine Oral Pathology Oral Radiology Pub Date : 2025-03-14 DOI: 10.1016/j.oooo.2025.01.071

Eduardo dos Santos Vidal, William Cezar da Silveira, Hélen Kaline Farias Bezerra, Camila Cerantula Moura, Leandro Eduardo Klüppel, Pablo Agustin Vargas, Heliton Gustavo de Lima

{"title":"Adenoid ameloblastoma with dentinoid: a case report","authors":"Eduardo dos Santos Vidal, William Cezar da Silveira, Hélen Kaline Farias Bezerra, Camila Cerantula Moura, Leandro Eduardo Klüppel, Pablo Agustin Vargas, Heliton Gustavo de Lima","doi":"10.1016/j.oooo.2025.01.071","DOIUrl":"10.1016/j.oooo.2025.01.071","url":null,"abstract":"<div><div>A 32-year-old Caucasian female presented with a friable, hemorrhagic intraoral nodule associated with impacted tooth 48, exhibiting a roseus coloration, soft consistency, and a sessile with a 2 cm extension, evolving over a 3-year period. Cone-beam computed tomography revealed intraosseous evidence of a hypodense region associated with tooth 48. In the axial section, bone cortex expansion and buccal/lingual fenestrations were noted. Initial diagnostic considerations included dentigerous cyst and ameloblastoma. An incisional biopsy confirmed the diagnosis as conventional ameloblastoma with an acanthomatous pattern. Following complete lesion removal, microscopic analysis revealed, in addition to the ameloblastoma component, duct-like structures, a cribriform architecture, and the presence of dentinoid material, supported by positive immunohistochemical stains (CK19, CK14, β-catenin) and low Ki-67 (<5%), confirming adenoid ameloblastoma with dentinoid. While studies have documented cases of this new entity in the gnathic bones, further characterization is crucial for understanding its etiopathogenesis and biological behavior.</div></div>","PeriodicalId":49010,"journal":{"name":"Oral Surgery Oral Medicine Oral Pathology Oral Radiology","volume":"139 5","pages":"Pages e13-e14"},"PeriodicalIF":2.0,"publicationDate":"2025-03-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143620825","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Large myofibroma in the mandible of an adult woman: a case report

IF 2 3区医学

Oral Surgery Oral Medicine Oral Pathology Oral Radiology Pub Date : 2025-03-14 DOI: 10.1016/j.oooo.2025.01.028

Caroline Alfaia-Silva, José Renato Brandão, Tulio Silva Rosa, Filipe Modolo Siqueira, Elena Riet Correa Rivero, Rogério de Oliveira Gondak, Ricardo Luiz Cavalcanti de Albuquerque-Júnior

{"title":"Large myofibroma in the mandible of an adult woman: a case report","authors":"Caroline Alfaia-Silva, José Renato Brandão, Tulio Silva Rosa, Filipe Modolo Siqueira, Elena Riet Correa Rivero, Rogério de Oliveira Gondak, Ricardo Luiz Cavalcanti de Albuquerque-Júnior","doi":"10.1016/j.oooo.2025.01.028","DOIUrl":"10.1016/j.oooo.2025.01.028","url":null,"abstract":"<div><div>The myofibroma is a benign mesenchymal neoplasm of perivascular myoid cells that forms a spectrum with myopericytoma. We report the case of a 39-year-old woman with a unilocular radiolucent lesion in the mandible, extending from the mesial of the left first molar to near the incisura. Computed tomography showed a well-defined hypodense lesion. Incisional biopsy revealed a biphasic proliferation of round to spindle-shaped cells, with various fascicular patterns and narrow blood vessels surrounded by tumor cells. The stroma was predominantly myxoid, with low mitotic activity. Adjacent to the lesion, densely collagenized fibrous connective tissue, peripheral nerve fibers, and fragments of mucoserous acini from salivary glands were observed. Immunohistochemistry was positive for SMA and podoplanin. The diagnosis of myofibroma was established, highlighting its histological morphology and adjacent characteristics. Intraosseous myofibroma requires meticulous clinical-histological-radiological investigation, combined with an immunohistochemical marker panel, aiding in its diagnosis. The patient is awaiting tumor removal.</div></div>","PeriodicalId":49010,"journal":{"name":"Oral Surgery Oral Medicine Oral Pathology Oral Radiology","volume":"139 5","pages":"Page e5"},"PeriodicalIF":2.0,"publicationDate":"2025-03-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143620129","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0