{"title":"Incorporating critical assessment of emerging artificial intelligence tools into oral and maxillofacial pathology residency training.","authors":"Sarah G Fitzpatrick, Ahmed S Sultan","doi":"10.1016/j.oooo.2026.03.003","DOIUrl":"https://doi.org/10.1016/j.oooo.2026.03.003","url":null,"abstract":"","PeriodicalId":49010,"journal":{"name":"Oral Surgery Oral Medicine Oral Pathology Oral Radiology","volume":" ","pages":""},"PeriodicalIF":1.9,"publicationDate":"2026-03-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147724423","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Antonia Taiane Lopes de Moraes, Mateus José Dutra, Fábio Muradás Girardi, Fábio Rocha Lima, Márcio Ajudarte Lopes, Ana Lia Anbinder, Pablo Agustin Vargas, Vivian Petersen Wagner
{"title":"Histological spectrum of lip basal cell Carcinomas: a retrospective study.","authors":"Antonia Taiane Lopes de Moraes, Mateus José Dutra, Fábio Muradás Girardi, Fábio Rocha Lima, Márcio Ajudarte Lopes, Ana Lia Anbinder, Pablo Agustin Vargas, Vivian Petersen Wagner","doi":"10.1016/j.oooo.2026.02.019","DOIUrl":"https://doi.org/10.1016/j.oooo.2026.02.019","url":null,"abstract":"<p><strong>Objective: </strong>To characterize the histopathological subtypes of basal cell carcinoma (BCC) in the lip region, emphasizing common and rare morphological features and determining the proportion of high-risk tumors at this site.</p><p><strong>Study design: </strong>This study analyzed histopathological records of BCCs located in the lip and labial commissure regions in 3 Brazilian dental institutions. Demographic and clinical data were collected. Histopathological evaluation was independently performed by 3 oral pathologists and 1 dermatopathologist, with consensus reached when necessary. Tumors were classified according to contemporary histopathological criteria and stratified by risk based on World Health Organization guidelines.</p><p><strong>Results: </strong>Among 68 lip BCCs, the upper lip was the most frequently affected site (52.9%). The nodular subtype was the most prevalent (52.9%) and predominantly classified as low risk. However, 45.6% of tumors were considered high risk, mainly due to aggressive variants, including micronodular and sclerodermiform patterns, and mixed histological subtypes. Ulcerated lesions tended to be high risk (68.4%; P = .07). Depth of invasion (mean 1.27 mm) showed a tendency toward greater infiltration in high-risk tumors (P = .05).</p><p><strong>Conclusion: </strong>Lip BCCs exhibit marked histopathological heterogeneity. Although low-risk nodular tumors predominate, a substantial proportion present high-risk features, reinforcing the importance of detailed histopathological assessment.</p>","PeriodicalId":49010,"journal":{"name":"Oral Surgery Oral Medicine Oral Pathology Oral Radiology","volume":" ","pages":""},"PeriodicalIF":1.9,"publicationDate":"2026-03-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147724408","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Lilibeth-Stephania Escoto-Vasquez, Sarah Monserrat Lomelí-Martínez, Julieta Sarai Becerra-Ruiz, Alan Mauricio Solís-Velázquez, Giselle Berenice Vela-Sancho, Hripsime V Apresyan, Javier Flores-Fraile, Artak Heboyan, Mario Alberto Alarcón-Sánchez
{"title":"Clinicopathological findings of oral cavity leishmaniasis: a systematic review.","authors":"Lilibeth-Stephania Escoto-Vasquez, Sarah Monserrat Lomelí-Martínez, Julieta Sarai Becerra-Ruiz, Alan Mauricio Solís-Velázquez, Giselle Berenice Vela-Sancho, Hripsime V Apresyan, Javier Flores-Fraile, Artak Heboyan, Mario Alberto Alarcón-Sánchez","doi":"10.1016/j.oooo.2026.02.021","DOIUrl":"https://doi.org/10.1016/j.oooo.2026.02.021","url":null,"abstract":"<p><strong>Objective: </strong>This systematic review seeks to examine and synthesize the available literature on the clinical and pathological features of leishmaniasis affecting the oral cavity.</p><p><strong>Study design: </strong>A systematic review was conducted in accordance with PRISMA guidelines and registered in PROSPERO (CRD420251070738). PubMed, Web of Science, and Scopus were searched up to January 11, 2025. Inclusion criteria covered case reports and series with histopathological confirmation. Clinical, pathological, diagnostic, and treatment data were extracted. Study quality was assessed using the Joanna Briggs Institute (JBI) tools.</p><p><strong>Results: </strong>Fifty-one studies (40 case reports, 11 case series) involving 132 patients were included. The mean age was 41.2 years, with 87.8% male. Leishmania infantum (16.6%) and L. braziliensis (6.1%) were the most reported species. Ulcerative lesions (37.8%) and nodules (8.3%) predominated, commonly affecting the upper lip, soft palate, and buccal mucosa. Histopathology was the primary diagnostic method (78.7%). Meglumine antimoniate (37.1%) was the most used treatment. Recurrence occurred in 25% of cases after an average of 16.4 months of follow-up.</p><p><strong>Conclusion: </strong>Oral leishmaniasis is an uncommon clinical entity with varied presentation, requiring a high index of suspicion for accurate diagnosis. This review offers essential information to support early recognition and appropriate management.</p>","PeriodicalId":49010,"journal":{"name":"Oral Surgery Oral Medicine Oral Pathology Oral Radiology","volume":" ","pages":""},"PeriodicalIF":1.9,"publicationDate":"2026-03-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147724449","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Rebeca Valeska Soares Pereira, Joana de Ângelis Alves Silva, Laís Regina Silva Pereira, Rodolfo Ramos Castelo Branco, Ana Cláudia Amorim Gomes Dourado, Emanuel Sávio de Souza Andrade
{"title":"Evaluation of Kinesio taping in the postoperative period of zygomatic fractures: a randomized clinical trial.","authors":"Rebeca Valeska Soares Pereira, Joana de Ângelis Alves Silva, Laís Regina Silva Pereira, Rodolfo Ramos Castelo Branco, Ana Cláudia Amorim Gomes Dourado, Emanuel Sávio de Souza Andrade","doi":"10.1016/j.oooo.2026.03.002","DOIUrl":"https://doi.org/10.1016/j.oooo.2026.03.002","url":null,"abstract":"<p><strong>Objective: </strong>To evaluate the effects of Kinesio Taping (KT) on postoperative edema, trismus, and pain after surgical treatment of unilateral zygomatic complex fractures.</p><p><strong>Study design: </strong>Eighteen patients with unilateral zygomatic fractures were randomly allocated to a control group (no taping) or a KT group. Taping was applied using a compressive technique during the first 72 hours and a lymphatic technique until postoperative day 7. Edema was assessed by linear facial measurements at 6 time points and by stereophotogrammetry at 3 time points. Trismus and pain were also evaluated.</p><p><strong>Results: </strong>No statistically significant between-group differences were observed for linear edema measurements. Both groups showed significant edema reduction after 72 hours. Volumetric analysis showed higher mean facial volumes in the control group, without statistical significance. The KT group demonstrated a numerically greater mean increase in maximal mouth opening (8.67 mm) compared with controls (6.30 mm). Pain scores were consistently lower in the taping group, without statistical significance. No adverse events were reported.</p><p><strong>Conclusions: </strong>KT was safe and well-tolerated but did not demonstrate statistically significant superiority over standard postoperative care for edema, trismus, or pain in this sample. Three-dimensional stereophotogrammetry proved to be a sensitive method for postoperative facial volume assessment.</p>","PeriodicalId":49010,"journal":{"name":"Oral Surgery Oral Medicine Oral Pathology Oral Radiology","volume":" ","pages":""},"PeriodicalIF":1.9,"publicationDate":"2026-03-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147786688","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Brian Maloney, Min Seo Jung, Jason Byrne, Brian Martin, Esther O'Regan, John Edward O'Connell
{"title":"Diagnostic discrepancies in the surgical management of oral epithelial dysplasia - an analysis of concordance between incisional biopsy and definitive resection specimens.","authors":"Brian Maloney, Min Seo Jung, Jason Byrne, Brian Martin, Esther O'Regan, John Edward O'Connell","doi":"10.1016/j.oooo.2026.03.001","DOIUrl":"https://doi.org/10.1016/j.oooo.2026.03.001","url":null,"abstract":"<p><p>The management of oral potentially malignant disorders is primarily guided by the degree of oral epithelial dysplasia (OED) present on incisional biopsy. Despite the universal use of this technique to inform treatment decisions, this method harbours limitations which can result in the under- or overestimating the degree of OED when compared with the fully excised specimen.</p><p><strong>Objectives: </strong>There is a paucity of published work examining the reliability of incisional biopsy for oral potentially malignant disorders, representing a clear gap in our understanding of the reliability of this diagnostic technique as a mainstay in our management of these conditions.</p><p><strong>Study design: </strong>The current study retrospectively examined the agreement between the histological findings on incisional biopsy and subsequently excised specimens in a cohort of patients with known OED in oral leukoplakia specimens in a single maxillofacial unit between 2021 and 2024.</p><p><strong>Results: </strong>Of 88 total specimens, there was slight overall agreement between the two techniques. On subgroup analysis, for non-PVL OED, agreement was moderate, but agreement for PVL type OED was poor. A total of 31% of specimens were discordant, 41% with a lower degree of OED on biopsy versus excised specimen. The greatest discordance arose for moderate OED. Three factors for discordance were identified.</p><p><strong>Conclusion: </strong>This study has contributed to the evidence base by highlighting the discrepancies related to OED grading between incisional biopsy and resection specimens. While incisional biopsy is a dependable method for the diagnosis of non-PVL OED, its use in PVL highlights significant limitations. Reducing discordances requires an understanding of the causative factors and close collaboration between pathologists and clinicians.</p>","PeriodicalId":49010,"journal":{"name":"Oral Surgery Oral Medicine Oral Pathology Oral Radiology","volume":" ","pages":""},"PeriodicalIF":1.9,"publicationDate":"2026-03-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147785705","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Sebastião Silvério Sousa-Neto, Anna Luíza Damaceno Araújo
{"title":"Response to: Caution regarding clinical interpretation of convolutional neural network performance in the histopathological differentiation of salivary gland tumors.","authors":"Sebastião Silvério Sousa-Neto, Anna Luíza Damaceno Araújo","doi":"10.1016/j.oooo.2026.02.015","DOIUrl":"https://doi.org/10.1016/j.oooo.2026.02.015","url":null,"abstract":"","PeriodicalId":49010,"journal":{"name":"Oral Surgery Oral Medicine Oral Pathology Oral Radiology","volume":" ","pages":""},"PeriodicalIF":1.9,"publicationDate":"2026-03-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147654743","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Hacer Eberliköse, Tuğçe Akın, Arif Yiğit Güler, Berin Tuğtağ Demir, Hakan Alpay Karasu
{"title":"Impact of botulinum toxin type A on mandibular bone parameters in bruxism: radiographic evidence from treated, untreated, and healthy individuals.","authors":"Hacer Eberliköse, Tuğçe Akın, Arif Yiğit Güler, Berin Tuğtağ Demir, Hakan Alpay Karasu","doi":"10.1016/j.oooo.2026.01.011","DOIUrl":"https://doi.org/10.1016/j.oooo.2026.01.011","url":null,"abstract":"<p><strong>Objective: </strong>This study investigates the effects of botulinum toxin type A (BoNT-A) injections on mandibular bone morphology in bruxism patients through the use of panoramic radiography.</p><p><strong>Study design: </strong>Sixty patients were assessed and categorized into three groups: bruxism with BoNT-A injection, bruxism without BoNT-A injection, and healthy controls. Morphological classifications (G0-G3), mandibular angle depth (AMD), antegonial notch depth (AND), and cortical thickness (CT) were evaluated at baseline and after a six-month period.</p><p><strong>Results: </strong>The BoNT-A group demonstrated substantial decreases in G2 and G3 categories and enhancements in cortical thickness relative to noninjected and control groups (P < .05). However, no significant alterations were detected in AND values.</p><p><strong>Conclusion: </strong>The data indicate that BoNT-A diminishes problematic mandibular bone apposition and facilitates cortical remodeling by decrease excessive occlusal stresses. Panoramic radiographs can function as an effective instrument for both diagnosing bruxism and assessing treatment results.</p>","PeriodicalId":49010,"journal":{"name":"Oral Surgery Oral Medicine Oral Pathology Oral Radiology","volume":" ","pages":""},"PeriodicalIF":1.9,"publicationDate":"2026-03-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147356808","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Probability, diagnostic reasoning, and the most likely diagnosis","authors":"Steven H. Yale, Halil Tekiner, Eileen S. Yale","doi":"10.1016/j.oooo.2025.10.025","DOIUrl":"10.1016/j.oooo.2025.10.025","url":null,"abstract":"","PeriodicalId":49010,"journal":{"name":"Oral Surgery Oral Medicine Oral Pathology Oral Radiology","volume":"141 3","pages":"Pages 421-422"},"PeriodicalIF":1.9,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145726991","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Information for Readers","authors":"","doi":"10.1016/S2212-4403(25)01363-X","DOIUrl":"10.1016/S2212-4403(25)01363-X","url":null,"abstract":"","PeriodicalId":49010,"journal":{"name":"Oral Surgery Oral Medicine Oral Pathology Oral Radiology","volume":"141 3","pages":"Page A7"},"PeriodicalIF":1.9,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146039963","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Denis Talis Reis DDS, MSc , Iara Vieira Ferreira DDS, MSc , Eva Beatriz Freitas Braga DDS , Francielle Silvestre Verner DDS, PhD , Sibele Nascimento de Aquino DDS, PhD
{"title":"Clinical decision-making regarding histopathologic submission of tooth-associated lesional tissue","authors":"Denis Talis Reis DDS, MSc , Iara Vieira Ferreira DDS, MSc , Eva Beatriz Freitas Braga DDS , Francielle Silvestre Verner DDS, PhD , Sibele Nascimento de Aquino DDS, PhD","doi":"10.1016/j.oooo.2025.09.016","DOIUrl":"10.1016/j.oooo.2025.09.016","url":null,"abstract":"<div><h3>Objective</h3><div>Analyze factors influencing dentists’ decisions to discard or submit tissues from tooth-associated lesions, such as those associated with impacted teeth and periapices, for histopathological analysis.</div></div><div><h3>Study design</h3><div>Cross-sectional study via online questionnaire with dentists, assessing practices regarding excised tissue management, sociodemographic and professional characteristics. Descriptive statistics, chi-square tests, Student’s t-tests, and logistic regression were used for analysis, with significance at <em>p</em> < .05.</div></div><div><h3>Results</h3><div>Among 348 dentists (mean age 30.95 ± 9.24 years), 65.8% were female, 58.05% held postgraduate degrees, and 67.53% worked in private clinics. Most participants (85.63%) reported not submitting tooth-associated lesions for histopathological examination. Significant associations with tissue submission included, during dental education: access to pathology laboratories, exposure to anatomopathological reports, and perception of sufficient training in oral pathology and oral medicine. In professional practice, prior experience with biopsy requisition forms and exposure to anatomopathological reports were significant. Logistic regression identified 2 significant predictors of tissue submission: perception of sufficient training in oral pathology and oral medicine during dental education, and exposure to anatomopathological reports in professional practice.</div></div><div><h3>Conclusions</h3><div>Although histopathology is crucial for diagnosis, tissue discard remains frequent. These findings highlight the importance of strengthening dental education and clinical training in management of excised tissues in dentistry.</div></div>","PeriodicalId":49010,"journal":{"name":"Oral Surgery Oral Medicine Oral Pathology Oral Radiology","volume":"141 3","pages":"Pages 379-386"},"PeriodicalIF":1.9,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145460455","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}