Josefina Martínez-Ramírez, Sibele Nascimento de Aquino, Hélen Kaline Farias Bezerra, Mario Fernando de Góes, Alan Roger Santos-Silva, Pablo Agustin Vargas, Márcio Ajudarte Lopes
{"title":"Unusual gingival reaction related to foreign body hydroxyapatite: a case report","authors":"Josefina Martínez-Ramírez, Sibele Nascimento de Aquino, Hélen Kaline Farias Bezerra, Mario Fernando de Góes, Alan Roger Santos-Silva, Pablo Agustin Vargas, Márcio Ajudarte Lopes","doi":"10.1016/j.oooo.2025.01.017","DOIUrl":"10.1016/j.oooo.2025.01.017","url":null,"abstract":"<div><div>A 56-year-old woman was referred for evaluation and management of 2 asymptomatic vestibular gingival lesions in the areas of both upper lateral incisors. These 2 teeth were missing, and the areas were rehabilitated with dental implants and crowns. The patient reported that was previously treated in another service with systematic antibiotics and antiseptic mouthwash without resolution. She denied tobacco and alcohol use and her medical history includes a stroke medicated with clopidogrel. Clinical examination revealed 2 nodular lesions with erythematous and whitish areas on the marginal gingiva, with approximately 1 cm each. Cone beam computed tomography revealed extraosseous hyperdense particles along the bilateral buccal cortical bone of the dental implants. Microscopic examination showed intense chronic inflammation associated with numerous birefringent structures with rectangular and triangular shapes immediately subjacent to the epithelium. Energy-dispersive X-ray analysis revealed calcium and phosphate as the main elements of the foreign body, allowing comparison with pure hydroxyapatite to confirm the similarity in composition. The case is especially unique due to the identification of an enlarged gingival reaction to hydroxyapatite.</div></div>","PeriodicalId":49010,"journal":{"name":"Oral Surgery Oral Medicine Oral Pathology Oral Radiology","volume":"139 5","pages":"Page e3"},"PeriodicalIF":2.0,"publicationDate":"2025-03-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143620133","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Núbia Rafaelle Oliveira de Meneses, Luciana Munhoz, Erika Antonia dos Anjos Ramos, Alice Souza Villar Cassimiro Fonseca, Lucila Massu Yoshizaki Akinaga Moreira, Daniela Miranda Richarte de Andrade Salgado, Claudio Costa
{"title":"Case report: extranodal T-cell lymphoma (natural killer) mimicking a dentoalveolar abscess","authors":"Núbia Rafaelle Oliveira de Meneses, Luciana Munhoz, Erika Antonia dos Anjos Ramos, Alice Souza Villar Cassimiro Fonseca, Lucila Massu Yoshizaki Akinaga Moreira, Daniela Miranda Richarte de Andrade Salgado, Claudio Costa","doi":"10.1016/j.oooo.2025.01.076","DOIUrl":"10.1016/j.oooo.2025.01.076","url":null,"abstract":"<div><div>T-cell lymphoma (natural killer) is a malignant neoplasm rarely developing extranodal and may mimic odontogenic alterations in the maxillofacial region. A pheoderma 41-year-old woman came to the dental service complaining of painful orofacial symptoms and fever. Clinical examination revealed intra- and extra-oral swelling on the left cheek, marked mobility, and endodontic involvement of the ipsilateral upper molars. The primary diagnostic hypothesis was an acute dentoalveolar abscess, with an initial approach of antibiotic therapy. After 2 weeks, the patients’ pain complaint was persistent, and rapid progression of the facial edema was observed. A computed tomography scan was carried out, which showed an image with soft tissue density, promoting discontinuity of the anterior and lateral walls of the left maxillary sinus. The pathological examination revealed a malignant neoplasm, whose histological type characterizes extranodal T-cell lymphoma (ENKL) in the left maxillary sinus. The proposed treatment for this condition includes radiotherapy and chemotherapy.</div></div>","PeriodicalId":49010,"journal":{"name":"Oral Surgery Oral Medicine Oral Pathology Oral Radiology","volume":"139 5","pages":"Pages e14-e15"},"PeriodicalIF":2.0,"publicationDate":"2025-03-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143620698","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Caroline Fernandes da Costa, Caroline de Almeida Reis, Jennifer Maia Alves da Silva, Julliany Taverny Sousa, Patrícia Teixeira de Oliveira, Joabe dos Santos Pereira, Lélia Maria Guedes Queiroz
{"title":"Amyloidosis associated with multiple myeloma: case report","authors":"Caroline Fernandes da Costa, Caroline de Almeida Reis, Jennifer Maia Alves da Silva, Julliany Taverny Sousa, Patrícia Teixeira de Oliveira, Joabe dos Santos Pereira, Lélia Maria Guedes Queiroz","doi":"10.1016/j.oooo.2025.01.063","DOIUrl":"10.1016/j.oooo.2025.01.063","url":null,"abstract":"<div><div>Amyloidosis is a debilitating disease with systemic or local manifestation characterized by progressive extracellular deposition of insoluble proteins that can affect multiple organs. A 72-year-old male patient, with a history of hyperthyroidism, dysphagia, and weight loss, was referred by the physician due to edema and erythema on the tongue. Upon extraoral examination, petechiae near the eyes and hemorrhagic discharge in the right eye were observed. Intraoral examination revealed macroglossia and normochromic nodular lesions on the tongue, as well as petechiae on the palate and buccal mucosa. With clinical suspicion of amyloidosis, an incisional biopsy was performed. Histopathological examination revealed extracellular deposits of homogeneous eosinophilic amorphous material, suggestive of amyloidosis. The diagnosis was confirmed through histochemical examination with Congo red stain. The patient was referred to the medical service for investigation of multifocal organ involvement, was diagnosed with multiple myeloma, and is currently undergoing chemotherapy treatment.</div></div>","PeriodicalId":49010,"journal":{"name":"Oral Surgery Oral Medicine Oral Pathology Oral Radiology","volume":"139 5","pages":"Page e12"},"PeriodicalIF":2.0,"publicationDate":"2025-03-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143620697","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Juliana Figueiredo da Roza, Carlos Augusto Aquino Negreiros, Letícia da Silva Soares Gomes, Sabrina Elora de Almeida Correa, Natasha Araújo Mota, Jeconias Câmara, Tatiana Nayara Libório-Kimura
{"title":"Psammomatoid juvenile ossifying fibroma in a male patient with crouzon syndrome","authors":"Juliana Figueiredo da Roza, Carlos Augusto Aquino Negreiros, Letícia da Silva Soares Gomes, Sabrina Elora de Almeida Correa, Natasha Araújo Mota, Jeconias Câmara, Tatiana Nayara Libório-Kimura","doi":"10.1016/j.oooo.2025.01.081","DOIUrl":"10.1016/j.oooo.2025.01.081","url":null,"abstract":"<div><div>A 16-year-old male patient, with Crouzon syndrome and severe bone deformity was referred to a hospital after an orthodontics evaluation, which detected a hyperdense circumscribed image in the maxilla during a facial computed tomography examination. The patient had anosmia and clinically a slight painless bulging in the anterior maxilla. An excisional biopsy with peripheral osteotomy was performed and the material was sent for histopathological analysis with under hypothesis of osteoma or fibrous dysplasia. Microscopically, there were benign fibro-osseous lesions characterized by hypercellular fibrous connective tissue, containing multiple ossicles with variable sizes and shapes, from spherical, oval to irregular and eosinophilic, with few basophilic areas similar to calcification, many with a brush border. Vital bone trabeculae were observed bordering the lesion and erythrocyte extravasation was compatible with psammomatoid juvenile ossifying fibroma. There was no need for further treatment and the patient remains under oral and maxillofacial follow-up for future orthognathic surgery.</div></div>","PeriodicalId":49010,"journal":{"name":"Oral Surgery Oral Medicine Oral Pathology Oral Radiology","volume":"139 5","pages":"Pages e15-e16"},"PeriodicalIF":2.0,"publicationDate":"2025-03-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143620702","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Daiana da Silva Ferreira, Ana Rita Vianna Potrich, Amanda de Farias Gabriel, Lauren Neumann Villarinho, Julia Souza Führ, Marco Antonio Trevizani Martins, Manoela Domingues Martins
{"title":"Medication-related osteonecrosis of the jaw: a case report","authors":"Daiana da Silva Ferreira, Ana Rita Vianna Potrich, Amanda de Farias Gabriel, Lauren Neumann Villarinho, Julia Souza Führ, Marco Antonio Trevizani Martins, Manoela Domingues Martins","doi":"10.1016/j.oooo.2025.01.079","DOIUrl":"10.1016/j.oooo.2025.01.079","url":null,"abstract":"<div><div>Medication-related osteonecrosis of the jaw (MROJ) represents a challenge for patients taking antiangiogenic and antiresorptive medications. Here we present a case involving a 55-year-old man with lupus and type 2 diabetes, treated with alendronate sodium. After multiple extractions, there was bone exposure accompanied by an infectious condition in the operated regions. In addition, he had ulcers and erythema on the oral mucosa. Surgical interventions of debridement of necrotic bone tissue, antimicrobial photodynamic therapy (aPDT) and photobiomodulation (FBM) were used as treatment, we addressed his MROJ. After carrying out the proposed treatment, the lesions are in remission but are still being monitored. Laser technology, increasingly favored for surgeries and therapies such as aPDT and FBM, was fundamental. Although this multidimensional approach shows promise, thorough studies are imperative to assess relapse risks and long-term outcomes. This study emphasizes the continued need to refine MROJ treatments, given their complexity and profound implications.</div></div>","PeriodicalId":49010,"journal":{"name":"Oral Surgery Oral Medicine Oral Pathology Oral Radiology","volume":"139 5","pages":"Page e15"},"PeriodicalIF":2.0,"publicationDate":"2025-03-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143620699","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Nara Rúbia Pereira de Siqueira, Filipe Moreira Biokino, Vanessa Milani, Douglas Rangel Goulart, Diego Antonio Costa Arantes, Elismauro Francisco de Mendonça, Rejane Faria Ribeiro-Rotta
{"title":"Screening of erythematous petechiae and macules as indicators of systemic diseases: a case report","authors":"Nara Rúbia Pereira de Siqueira, Filipe Moreira Biokino, Vanessa Milani, Douglas Rangel Goulart, Diego Antonio Costa Arantes, Elismauro Francisco de Mendonça, Rejane Faria Ribeiro-Rotta","doi":"10.1016/j.oooo.2025.01.065","DOIUrl":"10.1016/j.oooo.2025.01.065","url":null,"abstract":"<div><div>Oral mucosa alterations can be part of screening for various diseases. A 39-year-old white woman, with lower lip erythematous macules for 5 years, worsting in 2 months with bleeding upon minimal trauma and healing delay. History of 10 years of working sun overexposure, treated anemia, no chronic medication. Current blood tests are within normal limits. Labial mucosa, gingiva, dorsum of the tongue, buccal mucosa, and fingertips presented erythematous petechiae. Lower lip incisional biopsy reported capillary hemangioma. Clinical diagnosis pointed toward hereditary hemorrhagic telangiectasia, as the patient reported recurrent spontaneous epistaxis and her 18-year-old daughter exhibited similar symptoms. Differential diagnosis was considered for CREST syndrome. She was referred to a physician to investigate possible arteriovenous malformations involving the lungs, liver, or central nervous system. Lip lesions were successfully treated with ethanolamine. The dentist can play a decisive role in the diagnosis of systemic diseases if he thoroughly explores the whole patient's history.</div></div>","PeriodicalId":49010,"journal":{"name":"Oral Surgery Oral Medicine Oral Pathology Oral Radiology","volume":"139 5","pages":"Page e12"},"PeriodicalIF":2.0,"publicationDate":"2025-03-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143619868","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Yuri Kalinin, Vanessa Cristina de Branco Gonçalves, Ivan José Correia-Neto, Suellen Vieira do Nascimento, Lucas Lacerda de Souza
{"title":"Oral Kaposis sarcoma report of 4 cases","authors":"Yuri Kalinin, Vanessa Cristina de Branco Gonçalves, Ivan José Correia-Neto, Suellen Vieira do Nascimento, Lucas Lacerda de Souza","doi":"10.1016/j.oooo.2025.01.060","DOIUrl":"10.1016/j.oooo.2025.01.060","url":null,"abstract":"<div><div>Oral Kaposi's Sarcoma (KS) presents a significant diagnostic challenge and is an important indicator of HIV/AIDS. This study aims to present a case series involving 4 male patients with a mean age of 28.5 years (range 22-39). The patients exhibited reddish, ulcerated, and bleeding lesions on the hard palate and gingiva, along with disseminated lesions. Incisional biopsies revealed spindle cell proliferation and slit-like vascular spaces, with immunohistochemistry positive for CD34 and HHV-8 markers, confirming the diagnosis of KS. For 2 patients, oral KS was the initial sign of HIV infection, which was also indicated by increased viral loads and decreased CD4/T cell counts. All patients were referred for treatment and have been under follow-up for an average of 30.5 months (range 2-48). This highlights the importance of recognizing oral KS as an early indicator of HIV and advocates for a comprehensive, multidisciplinary management approach to systemic diseases.</div></div>","PeriodicalId":49010,"journal":{"name":"Oral Surgery Oral Medicine Oral Pathology Oral Radiology","volume":"139 5","pages":"Page e11"},"PeriodicalIF":2.0,"publicationDate":"2025-03-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143619940","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Central giant cell lesion in the maxilla: from differential diagnosis of brown tumor to death due to COVID-19","authors":"Thiago Macedo Marques, Livia Bino Marques","doi":"10.1016/j.oooo.2025.01.048","DOIUrl":"10.1016/j.oooo.2025.01.048","url":null,"abstract":"<div><div>A 28-year-old female patient, presented with a nodule in the right maxilla for approximately 60 days, which worsened following the extraction of teeth 16 and 17 due to a suspected dental focus lesion. Intraoral examination revealed a single tumor extending from the palate to the alveolar ridge, with an intact surface on the palate and ulcerated on the ridge. No cervical lymphadenopathy was observed on extrabuccal examination. The patient reported spontaneous pain, partially alleviated by analgesics. Laboratory tests indicated elevated levels of urea and creatinine. An incisional biopsy was performed, and histological analysis suggested a Central Giant Cell Lesion. The possibility of a Brown Tumor of Hyperparathyroidism was considered due to the laboratory findings, but it was not confirmed due to the patient's death from COVID-19 during hospitalization for dialytic therapy following the exacerbation of renal disease.</div></div>","PeriodicalId":49010,"journal":{"name":"Oral Surgery Oral Medicine Oral Pathology Oral Radiology","volume":"139 5","pages":"Page e9"},"PeriodicalIF":2.0,"publicationDate":"2025-03-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143619942","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Luís Otávio Pereira da Silva, Roberta Rayra Martins Chaves, Maurício Augusto Aquino de Castro, Wagner Henriques de Castro, Ricardo Santiago Gomez, Ricardo Alves Mesquita
{"title":"Ultrasound-guided fine-needle aspiration: effective diagnosis of a pleomorphic adenoma in the upper lip","authors":"Luís Otávio Pereira da Silva, Roberta Rayra Martins Chaves, Maurício Augusto Aquino de Castro, Wagner Henriques de Castro, Ricardo Santiago Gomez, Ricardo Alves Mesquita","doi":"10.1016/j.oooo.2025.01.044","DOIUrl":"10.1016/j.oooo.2025.01.044","url":null,"abstract":"<div><div>Fine-needle aspiration (FNA) is a highly accurate and cost-efficient method commonly employed for salivary gland issues, encompassing a spectrum from inflammation to tumors, which may be either neoplastic or not. A 25-year-old female patient presented with a 50-mm nodule, circumscribed, on the upper right lip, rubbery in consistency and smooth surface, with coloration similar to that of the mucosa, evolving over 6 years. Ultrasound-guided FNA was performed and material was assessed for liquid-based cytology (LBC). Examination of the LBC revealed the presence of individual or clustered cells with normochromic nuclei displaced to the periphery and eosinophilic cytoplasm with morphology resembling that of a plasma cell, suggestive of pleomorphic adenoma. An incisional biopsy was performed, and a diagnosis of the pleomorphic adenoma was made. The patient was treated by surgical approach and is without recurrence. The ultrasound-guided FNA is an ancillary tool for diagnosis of salivary gland diseases.</div></div>","PeriodicalId":49010,"journal":{"name":"Oral Surgery Oral Medicine Oral Pathology Oral Radiology","volume":"139 5","pages":"Page e8"},"PeriodicalIF":2.0,"publicationDate":"2025-03-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143619998","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Maria Renata Caballero, Lettieri Pinto, Victor Samuel de Almeida Lopes, Keila Martha Amorim Barroso, Paulo Rogerio Ferreti Bonan
{"title":"Mycobacterium fortuitum infection after cosmetic procedure with poly-l-lactic acid: a case report","authors":"Maria Renata Caballero, Lettieri Pinto, Victor Samuel de Almeida Lopes, Keila Martha Amorim Barroso, Paulo Rogerio Ferreti Bonan","doi":"10.1016/j.oooo.2025.01.031","DOIUrl":"10.1016/j.oooo.2025.01.031","url":null,"abstract":"<div><div>A 60-year female patient sought care at the dental diagnostic service of the Lauro Wanderley University Hospital with an infection caused by Mycobacterium fortuitum, a type of nontuberculosis mycobacterium and rapidly developed after the aesthetic procedure of filling with poly-l-lactic acid, better known commercially as Sculptra. At the extra-oral examination, the patient presented swelling on the right side of the face, near the labial commissure, without abnormalities intraorally. The patient did not present systemic diseases or report the use of alcohol, cigarettes, or illicit drugs. The infection was confirmed by ultrasonography, blood count, and culture test, and has been treated with an association of antibiotics, such as levofloxacin and ciprofloxacin, and accompanied by a specialized doctor.</div></div>","PeriodicalId":49010,"journal":{"name":"Oral Surgery Oral Medicine Oral Pathology Oral Radiology","volume":"139 5","pages":"Page e6"},"PeriodicalIF":2.0,"publicationDate":"2025-03-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143620011","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}