Ariadne Padilha de Andrade, Ana Claudia Luiz, Bruno Gaia, Maurício Gomes, Rodrigo N. Lopes, Vanessa Tilly, Thais Bianca Brandão
{"title":"A rare case of leiomyosarcoma on the floor of the mouth with prosthetic rehabilitation using implants: 2-year follow-up","authors":"Ariadne Padilha de Andrade, Ana Claudia Luiz, Bruno Gaia, Maurício Gomes, Rodrigo N. Lopes, Vanessa Tilly, Thais Bianca Brandão","doi":"10.1016/j.oooo.2025.01.023","DOIUrl":"10.1016/j.oooo.2025.01.023","url":null,"abstract":"","PeriodicalId":49010,"journal":{"name":"Oral Surgery Oral Medicine Oral Pathology Oral Radiology","volume":"139 5","pages":"Page e4"},"PeriodicalIF":2.0,"publicationDate":"2025-03-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143620124","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Isabela Lorrane Mota do Nascimento, Raquel D'Aquino Garcia Caminha, Mailon Cury Carneiro, Ana Cristina Xavier Neves, Alexandre Simões Garcia, Paulo Sergio da Silva Santos
{"title":"The consequences of late diagnosis and the importance of complementary examinations in oral squamous cell carcinoma","authors":"Isabela Lorrane Mota do Nascimento, Raquel D'Aquino Garcia Caminha, Mailon Cury Carneiro, Ana Cristina Xavier Neves, Alexandre Simões Garcia, Paulo Sergio da Silva Santos","doi":"10.1016/j.oooo.2025.01.019","DOIUrl":"10.1016/j.oooo.2025.01.019","url":null,"abstract":"<div><div>A 73-year-old female sought dental treatment for an erythematous ulcer in her alveolar mucosa, initially thought to be an odontogenic infection. After extracting teeth 17 and 18 with no improvement, Pemphigus Vulgaris was diagnosed and treated for 2 years with laser therapy and oral corticosteroids. Multiple erythematous ulcers with irregular nodular margins were present across the right hemiarch, in the vestibulo-palatal alveolar mucosa area, and in the anterior portion of the right hard palate. Another specialist performed an incisional biopsy, revealing aggressive Squamous Cell Carcinoma, staged as pT3 pN3b. The patient underwent partial maxillectomy, neck dissection, and radiotherapy. To reduce radiotherapy-induced oral symptoms, pre- and postneoplastic therapy evaluations were conducted. The importance of an early biopsy to avoid delayed diagnoses and mutilating therapies is highlighted, as is the need for active surveillance and complementary tests for a precise and swift diagnosis.</div></div>","PeriodicalId":49010,"journal":{"name":"Oral Surgery Oral Medicine Oral Pathology Oral Radiology","volume":"139 5","pages":"Page e3"},"PeriodicalIF":2.0,"publicationDate":"2025-03-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143620120","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ana Luiza Medeiros Cesar, Bruna Lavinas Sayed Picciani, Juliana Tristão Werneck, Maria Carolina de Lima Jacy Monteiro Barki, Eduarda Henrique Portugal, Abel Sobrinho de Freitas Vianna, Karla Bianca Fernandes da Costa Fontes
{"title":"High potency diode laser as a therapeutic alternative in oral vascular lesions: the comparison of 2 protocols","authors":"Ana Luiza Medeiros Cesar, Bruna Lavinas Sayed Picciani, Juliana Tristão Werneck, Maria Carolina de Lima Jacy Monteiro Barki, Eduarda Henrique Portugal, Abel Sobrinho de Freitas Vianna, Karla Bianca Fernandes da Costa Fontes","doi":"10.1016/j.oooo.2025.01.029","DOIUrl":"10.1016/j.oooo.2025.01.029","url":null,"abstract":"<div><div>An 11-year-old male patient presented 2 erythematous macules on the upper gum, above the central incisors, after using maxillary expansion 1 year ago. Given the positive diascopy, the diagnostic hypothesis was a vascular lesion. Two different protocols using photocoagulation with a high potency 980 nm diode laser (Thera Lase Surgery, DMC, SP, Brazil) were chosen for the treatment. There were 2 lesions in the attached gum: in tooth 11 a 1W and continuous mode were used, whereas in tooth 21, a 2W and pulsed mode were used. Consequently, within 14 days, an ulcer was observed only in the region of the former, and after 30 days, there was complete remission of the lesions in both regions; a better appearance on the left side was observed, though. It is concluded that photocoagulation with a high-potency diode laser is an effective option for oral vascular lesions, with the pulsed mode being preferable.</div></div>","PeriodicalId":49010,"journal":{"name":"Oral Surgery Oral Medicine Oral Pathology Oral Radiology","volume":"139 5","pages":"Page e5"},"PeriodicalIF":2.0,"publicationDate":"2025-03-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143620130","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Gabriela Fonseca Rocha, Heitor Abergoni da Silveira, Herberth Campos Silva, Fernando Chahud, Mariangela Ottoboni Brunaldi, Ana Terezinha Marques Mesquita, Jorge Esquiche León
{"title":"CK20-/MCPyV+ Merkel cell carcinoma: a detailed immunohistochemical and in situ hybridization study","authors":"Gabriela Fonseca Rocha, Heitor Abergoni da Silveira, Herberth Campos Silva, Fernando Chahud, Mariangela Ottoboni Brunaldi, Ana Terezinha Marques Mesquita, Jorge Esquiche León","doi":"10.1016/j.oooo.2025.01.013","DOIUrl":"10.1016/j.oooo.2025.01.013","url":null,"abstract":"<div><div>Merkel cell carcinoma (MCC) is an uncommon aggressive neoplasm of neural crest origin, usually arising in sun-exposed skin of the head and neck. By immunohistochemistry, CK20 and MCPyV positivity are found in about 80% of MCC cases. A 78-year-old male was referred and presented a tumor mass on the right maxilla 4 months ago. Computed tomography revealed an extensive osteolytic lesion in the maxillary sinus extending into the nasal cavity. Microscopy revealed extensive necrosis areas admixed by sheets of hyperchromatic basophilic round cells exhibiting a “salt and pepper” chromatin pattern, which showed immunopositivity for pan-CKAE1/3, EMA, CD56, CD99 (weak), CD138, S100 (focal), synaptophysin, Fli-1, INSM1, MCPyV, SATB2, Rb (intact), p53 (wild-type) and Ki-67 (40%). Relevantly, CK20 and TTF-1, as well as high-risk HPV and EBER (by ISH), were negative. This case illustrates that a detailed immunohistochemical study is essential to adequately classify high-grade neuroendocrine carcinomas, especially CK20-MCC.</div></div>","PeriodicalId":49010,"journal":{"name":"Oral Surgery Oral Medicine Oral Pathology Oral Radiology","volume":"139 5","pages":"Page e2"},"PeriodicalIF":2.0,"publicationDate":"2025-03-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143620179","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Beatriz Bastos Macêdo, Liciane Mariano dos Santos Menezes, Ananda Pereira Oliveira, Jéssica Vieira de Jesus Cardoso, Gleicy Gabriela Vitória Spinola Carneiro Falcão, Viviane Almeida Sarmento, Patrícia Miranda Leite
{"title":"Acute myeloid leukemia with important oral manifestation after dental extraction: case report","authors":"Beatriz Bastos Macêdo, Liciane Mariano dos Santos Menezes, Ananda Pereira Oliveira, Jéssica Vieira de Jesus Cardoso, Gleicy Gabriela Vitória Spinola Carneiro Falcão, Viviane Almeida Sarmento, Patrícia Miranda Leite","doi":"10.1016/j.oooo.2025.01.080","DOIUrl":"10.1016/j.oooo.2025.01.080","url":null,"abstract":"<div><div>Acute Myeloid Leukemia (AML) is the most prevalent leukemia in adults, characterized by the uncontrolled proliferation of hematopoietic stem cells. A 44-year-old woman, a smoker, presented with spontaneous pain in the region of the lower incisors. In dental care, she underwent tooth extraction. After 1 month, the patient presented complications due to hemorrhage and later exuberant progressive gingival hyperplasia. Evaluation revealed leukocytosis with increased blast count, confirming AML. Therapeutic interventions involved prophylactic and therapeutic antiviral treatment, antibiotics, and granulocyte colony-stimulating factor, but the patient deteriorated rapidly and died. After CT, there was remission of gingival hyperplasia. This case underscores the diagnostic challenges of AML, as it may present with initial unusual symptoms. Dental professionals should be aware of hematologic malignancies that can manifest with oral symptoms and this diagnosis is crucial to optimize patient outcomes.</div></div>","PeriodicalId":49010,"journal":{"name":"Oral Surgery Oral Medicine Oral Pathology Oral Radiology","volume":"139 5","pages":"Page e15"},"PeriodicalIF":2.0,"publicationDate":"2025-03-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143620700","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Marilia Nanni Vieira, Thaís Xavier Pereira da Silva, Dárcio Kitakawa, Felipe da Silva Peralta, Monica Ghislaine Oliveria Alves, Luis Felipe das Chagas e Silva de Carvalho
{"title":"Osteomyelitis in the mandibular torus: case report","authors":"Marilia Nanni Vieira, Thaís Xavier Pereira da Silva, Dárcio Kitakawa, Felipe da Silva Peralta, Monica Ghislaine Oliveria Alves, Luis Felipe das Chagas e Silva de Carvalho","doi":"10.1016/j.oooo.2025.01.083","DOIUrl":"10.1016/j.oooo.2025.01.083","url":null,"abstract":"<div><div>Female patient, 41 years old, without systemic comorbidities, attended the appointment complaining of an increase in volume in the right mandibular torus. Clinical examination revealed local edema associated with redness and areas of suppuration. With the prescription of antibiotic therapy, there was slight improvement, and occlusal radiography and computed tomography were requested. Computed tomography revealed osteolytic and destructive areas, with a moth-eaten appearance. Given the diagnostic hypotheses of osteosarcoma and osteomyelitis, an incisional biopsy and curettage were performed. Intraoperatively, an extremely osteolytic area with crumbling bone and suppuration was noted, possibly indicating acute infection. The pathological examination confirmed the diagnosis of acute osteomyelitis. After 1 month, the patient remained healthy without signs of infection. Considering the challenging management of the case, it is important to highlight that due to the moth-eaten radiographic appearance, a biopsy is necessary to rule out the possibility of malignant neoplasms such as osteosarcoma.</div></div>","PeriodicalId":49010,"journal":{"name":"Oral Surgery Oral Medicine Oral Pathology Oral Radiology","volume":"139 5","pages":"Page e16"},"PeriodicalIF":2.0,"publicationDate":"2025-03-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143620704","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Amanda Feitoza da Silva, Letícia Beatriz da Cruz Santos, Mariana Bitu Ramos-Pinto, Thalwylla Reiler Morato dos Reis Moreira, Ivan Correia da Silva-Filho
{"title":"Treatment of bilateral ankylosis of the temporomandibular joint in a pediatric patient: case report","authors":"Amanda Feitoza da Silva, Letícia Beatriz da Cruz Santos, Mariana Bitu Ramos-Pinto, Thalwylla Reiler Morato dos Reis Moreira, Ivan Correia da Silva-Filho","doi":"10.1016/j.oooo.2025.01.078","DOIUrl":"10.1016/j.oooo.2025.01.078","url":null,"abstract":"<div><div>Ankylosis of the temporomandibular joint (TMJ) is a pathology characterized by the replacement of the normal architecture of the TMJ by fibrous or bone tissue, where there is fusion of the anatomical components of the joint, with trauma being the main cause. Male patient, 14 years old, with a history of trauma from a motorcycle accident, attended the oral and maxillofacial outpatient clinic complaining of limited mouth opening and facial asymmetry. On physical examination, it was possible to observe a maximum interincisal opening (MIO) of 4 mm and on imaging examination, bilateral ankylosis of the temporomandibular joints was observed. The proposed treatment was interpositional gap arthroplasty with a temporal muscle flap on the right side and gap arthroplasty on the left side. The patient developed an MIO of 35 mm during follow-up 6 months after surgery. The surgical techniques performed are excellent alternatives for treating this pathology in children.</div></div>","PeriodicalId":49010,"journal":{"name":"Oral Surgery Oral Medicine Oral Pathology Oral Radiology","volume":"139 5","pages":"Page e15"},"PeriodicalIF":2.0,"publicationDate":"2025-03-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143620823","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Daniel Augusto Barnabé Nobre, Ana Maria Avelar Marques, Tania Mara Pimenta Amaral, Sílvia Ferreira de Sousa, Ricardo Alves Mesquita, Maria Cássia Ferreira de Aguiar
{"title":"Bullous lichen planus: case report","authors":"Daniel Augusto Barnabé Nobre, Ana Maria Avelar Marques, Tania Mara Pimenta Amaral, Sílvia Ferreira de Sousa, Ricardo Alves Mesquita, Maria Cássia Ferreira de Aguiar","doi":"10.1016/j.oooo.2025.01.067","DOIUrl":"10.1016/j.oooo.2025.01.067","url":null,"abstract":"<div><div>Lichen planus is a mucocutaneous disorder with different clinical patterns. Bullous lichen planus is a rare entity. A 62-year-old man was referred to Oral Medicine complaining of painful lesions on his tongue making eating difficult. Stress was associated with reported symptoms. Clinical examination showed on lateral edge of the tongue, radiating white plaques and ulcerations resulting from blisters with liquid content. In the posterior buccal mucosa, a white reticular plaque was observed. An incisional biopsy was performed on the left lateral edge of the tongue, and the diagnosis of lichen planus was made. The histopathological examination showed hyperkeratinized stratified squamous epithelium, showing areas of exocytosis, degeneration of the basal layer and Civatte bodies, and intense lymphocytic inflammatory infiltrate, arranged in a subepithelial band. Dexamethasone mouthwash 0.1 mg/mL was prescribed for 15 days. The lesion regressed after this period, recurring after the mouthwash was discontinued.</div></div>","PeriodicalId":49010,"journal":{"name":"Oral Surgery Oral Medicine Oral Pathology Oral Radiology","volume":"139 5","pages":"Page e13"},"PeriodicalIF":2.0,"publicationDate":"2025-03-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143619836","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Marcelle Bairral Ecard, Adriana Terezinha Neves Novellino Alves, Ana Flávia Schueler de Assumpção Leite, Silvia Paula de Oliveira, Marcos Alexandre Nunes, Fernando Luiz Dias, Simone de Queiroz Chaves Lourenço
{"title":"Early diagnosis after oral cancer treatment in a patient without risk factors: case report","authors":"Marcelle Bairral Ecard, Adriana Terezinha Neves Novellino Alves, Ana Flávia Schueler de Assumpção Leite, Silvia Paula de Oliveira, Marcos Alexandre Nunes, Fernando Luiz Dias, Simone de Queiroz Chaves Lourenço","doi":"10.1016/j.oooo.2025.01.068","DOIUrl":"10.1016/j.oooo.2025.01.068","url":null,"abstract":"<div><div>Man, 45 years old, leukoederma, denies smoking and alcohol consumption, history of adenomas and intestinal polyps, family medical history of breast cancer (mother) and lung cancer (uncle). Intraoral examination, heterogeneous leukoerythroplastic plaque was observed on right lingual belly. Incisional biopsy was performed using TAT (positive). Histopathological report of microinvasive squamous cell carcinoma. Patient treated by head and neck surgeon, with well-differentiated squamous cell carcinoma as histopathological report. One year of follow-up, a leukoplastic plaque with an erythematous center was observed in the same region as the diagnosed oral cancer. New incisional biopsy was performed using TAT (positive), with a histopathological diagnosis of severe epithelial dysplasia and sent for complete removal of the lesion. Histopathological report of epithelial hyperplasia without atypia. This case portrays the importance of monitoring patients diagnosed with oral squamous cell carcinoma and highlights that future investigations should be carried out in patients without a known risk factor.</div></div>","PeriodicalId":49010,"journal":{"name":"Oral Surgery Oral Medicine Oral Pathology Oral Radiology","volume":"139 5","pages":"Page e13"},"PeriodicalIF":2.0,"publicationDate":"2025-03-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143619837","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jefferson Lucas Mendes, Malena Josefhe Ferreira de Queiroz, Letícia Targino Campos, Cassiano Francisco Weege Nonaka, John Lennon Silva Cunha, Manuel Antônio Gordón-Núñez, Pollianna Muniz Alves
{"title":"Congenital granular cell epulis: a case report of paediatric tumor of newborn in mandible","authors":"Jefferson Lucas Mendes, Malena Josefhe Ferreira de Queiroz, Letícia Targino Campos, Cassiano Francisco Weege Nonaka, John Lennon Silva Cunha, Manuel Antônio Gordón-Núñez, Pollianna Muniz Alves","doi":"10.1016/j.oooo.2025.01.066","DOIUrl":"10.1016/j.oooo.2025.01.066","url":null,"abstract":"<div><div>Congenital granular cell epulis (CGCE) is a rare congenital growth of unknown histogenesis. Usually, CGCE develops on the maxillary alveolar ridge of a newborn, and that can lead to dysphagia and dyspnea. We report a case of a 47-day-old female neonate who presented with one exophytic lesion in the left mandibular alveolar ridge. Intraoral examination revealed a smooth-surfaced, pedunculated mass with normal coloration. Excisional biopsy was performed, and the histopathological findings revealed a tumor composed of sheets of round to polyhedral cells with granular cytoplasm and eccentrically placed hyperchromatic nuclei. These findings led to the diagnosis of CGCE. This lesion demonstrates an excellent prognosis, without being associated with any syndromes/genetic defects or malignant transformation. Healthcare professionals should be able to recognize and intervene in such rare entities.</div></div>","PeriodicalId":49010,"journal":{"name":"Oral Surgery Oral Medicine Oral Pathology Oral Radiology","volume":"139 5","pages":"Pages e12-e13"},"PeriodicalIF":2.0,"publicationDate":"2025-03-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143619869","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}