Victor Samuel de Almeida Lopes, Maria Renata Caballero Lettieri Pinto, Cláudia Roberta Leite Vieira de Figueiredo, Keila Martha Amorim Barroso, Ricardo Villar Beltrão, Paulo Rogerio Ferreti Bonan
{"title":"Peripheral fibromyxoma: a case report focusing on differential diagnosis","authors":"Victor Samuel de Almeida Lopes, Maria Renata Caballero Lettieri Pinto, Cláudia Roberta Leite Vieira de Figueiredo, Keila Martha Amorim Barroso, Ricardo Villar Beltrão, Paulo Rogerio Ferreti Bonan","doi":"10.1016/j.oooo.2025.01.082","DOIUrl":"10.1016/j.oooo.2025.01.082","url":null,"abstract":"<div><div>Myxomas can be categorized as benign odontogenic lesion of ectomesenchyme, with the central and peripheral variants, being the last one much more uncommon. This case reported a nodular asymptomatic growth affecting a 35-year-old black female, causing facial asymmetry and difficulty in occlusion on anterior maxilla. The lesion was peripheral confirmed by periapical X-ray and cone beam tomography. Differential diagnosis included non-neoplastic proliferative processes. An excisional biopsy was taken, and histopathological analysis indicated a neoplasm with intermediate myxoid and fibrous stroma and with stellate and ovoid cells associated with focal mineralization without odontogenic epithelium. Alcian Blue staining revealed myxoid composition. The final diagnosis was peripheral fibromyxoma. The patient is following up without recurrence after 6 months.</div></div>","PeriodicalId":49010,"journal":{"name":"Oral Surgery Oral Medicine Oral Pathology Oral Radiology","volume":"139 5","pages":"Page e16"},"PeriodicalIF":2.0,"publicationDate":"2025-03-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143620703","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Gustavo Rocha Vita, Guilherme Ribeiro de Queiroz, Tessa de Lucena Botelho, Claudio Maranhão Pereira
{"title":"Atypical clinical presentation of oral erosive lichen planus: case report","authors":"Gustavo Rocha Vita, Guilherme Ribeiro de Queiroz, Tessa de Lucena Botelho, Claudio Maranhão Pereira","doi":"10.1016/j.oooo.2025.01.057","DOIUrl":"10.1016/j.oooo.2025.01.057","url":null,"abstract":"<div><div>Lichen planus is a mucocutaneous disease that often affects the oral cavity (OLP). Its etiology is still unclear, but it has been considered an autoimmune disease. OLP can manifest in various forms, with the most common being the reticular. This is characterized by the presence of white lines on the buccal mucosa bilaterally. The erosive variant presents symptomatic debilitating lesions. Treatment is primarily carried out with systemic corticosteroids. The present case reports a 23-year-old patient with erosive OLP, with a 6-month evolution. For 5 months, the patient underwent various therapeutic protocols with corticosteroids and immunosuppressants, but without any resolution. In the reported case, despite the patient not presenting skin lesions, she was referred to a dermatologist due to the side effects that the medication was causing, combined with the morbidity of the OLP lesions affecting her quality of life. As of the present moment, despite medical follow-up, the patient remains uncontrolled.</div></div>","PeriodicalId":49010,"journal":{"name":"Oral Surgery Oral Medicine Oral Pathology Oral Radiology","volume":"139 5","pages":"Page e11"},"PeriodicalIF":2.0,"publicationDate":"2025-03-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143619937","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Maria Sofia Schreiber Peralta, Fabián Junior Mendéz Colmán, María Eugenia Ayala Pereira, María Cristina Gómez Amarilla, Elisa Noemi Oviedo, Rosvita Estefania Cantero Eisenkolbl, Maria Alejandra Portillo Martinez
{"title":"Pigmented Intradermal Melanocytic Nevus: A Case Report","authors":"Maria Sofia Schreiber Peralta, Fabián Junior Mendéz Colmán, María Eugenia Ayala Pereira, María Cristina Gómez Amarilla, Elisa Noemi Oviedo, Rosvita Estefania Cantero Eisenkolbl, Maria Alejandra Portillo Martinez","doi":"10.1016/j.oooo.2025.01.047","DOIUrl":"10.1016/j.oooo.2025.01.047","url":null,"abstract":"<div><div>Nevi or Moles are raised, localized lesions that are mostly dark in color, mainly due to sunlight. They have a high risk of malignant transformation, due to sun exposure or chronic trauma. We present a male patient, 42 years old, who comes for dental treatment. During the oral and facial evaluation, a raised lesion is observed in the frontal region to the right of the midline, with a slight increase in pigmentation, and slight discomfort upon exposure. Solar, at the patient's request, the excisional biopsy was performed and sent for histopathological analysis, the result was a pigmented intradermal melanocytic nevus with significant activity in the dermo-epidermal junction where atypical melanocytes arranged in isolation were noted. This demonstrates the importance of performing an oral and facial checkup looking for dermal alterations in addition to mucosal alterations, fulfilling the purpose that corresponds to the health area.</div></div>","PeriodicalId":49010,"journal":{"name":"Oral Surgery Oral Medicine Oral Pathology Oral Radiology","volume":"139 5","pages":"Page e9"},"PeriodicalIF":2.0,"publicationDate":"2025-03-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143619941","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"An unusual case: malignant melanoma in the oral cavity","authors":"Bárbara Campo DallOrto Martins, Sergio Lins de-Azevedo-Vaz, Rossiene Motta Bertollo, Daniela Nascimento Silva, Águida Cristina Gomes Henriques Leitão, Danielle Resende Camisasca, Liliana Aparecida Pimenta de Barros","doi":"10.1016/j.oooo.2025.01.033","DOIUrl":"10.1016/j.oooo.2025.01.033","url":null,"abstract":"<div><div>Malignant melanoma in the oral cavity is rare, with uncertain etiology, possibly associated with pre-existing melanosis, dental irritation, cigarette smoking, alcohol use, and formaldehyde exposure. A 59-year-old white female complained of a darkened lesion that appeared 7 years ago, which increased after the lower first molar extraction. Intraorally, a 2 cm darkened lesion with irregular borders and irregular surface was identified on the lower right alveolar ridge. Radiographically, a radiolucent image compatible with a tooth socket after extraction was observed. The incisional biopsy and microscopic analysis revealed the proliferation of atypical melanocytes with neoplastic characteristics invading the connective tissue arranged in sheets and cords depositing brownish pigment, consistent with melanin. The final diagnosis was malignant melanoma. The patient underwent surgical treatment with follow-up. Although rare, malignant oral melanoma should be considered as a differential diagnosis for blackened patches in the oral cavity.</div></div>","PeriodicalId":49010,"journal":{"name":"Oral Surgery Oral Medicine Oral Pathology Oral Radiology","volume":"139 5","pages":"Page e6"},"PeriodicalIF":2.0,"publicationDate":"2025-03-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143620009","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Camila Dayla Melo Oliveira, Erika Martins Pereira, Raísa Sales de Sá, Jennifer Sanzya Silva de Araújo, Aluísio Cruz de Sousa Neto, Milena Daniela Freire Corsini, Thalita Santana
{"title":"Unusual radiographic aspects of conventional ossifying fibroma: 2 cases reported","authors":"Camila Dayla Melo Oliveira, Erika Martins Pereira, Raísa Sales de Sá, Jennifer Sanzya Silva de Araújo, Aluísio Cruz de Sousa Neto, Milena Daniela Freire Corsini, Thalita Santana","doi":"10.1016/j.oooo.2025.01.021","DOIUrl":"10.1016/j.oooo.2025.01.021","url":null,"abstract":"<div><div>Conventional ossifying fibroma (COF) is a benign bone neoplasm that predominantly affects the jawbones. We report 2 cases of COF arising in the mandible that radiographically resembled odontogenic cysts. The first case is from a female 15-year-old patient presenting an expansive radiolucent lesion in the mandible, between the left second premolar e and first molar (vital teeth). The clinical hypothesis was a periodontal lateral cyst. The second case presented as a radiolucent lesion mimicking a periapical cyst in a 23-year-old male patient. The lesion was associated with the canine and first lower left premolar, both teeth were vital, however, the second premolar had undergone endodontic therapy. Clinical hypotheses included inflammatory lesions and central giant cell granuloma. Both lesions underwent surgical excision and microscopic analyses revealed cellular fibrous tissue with mineralized product, including osteoid, bone, and basophilic acellular spherules, with a final diagnosis of COF. Both patients are under follow-up with no recurrences.</div></div>","PeriodicalId":49010,"journal":{"name":"Oral Surgery Oral Medicine Oral Pathology Oral Radiology","volume":"139 5","pages":"Page e4"},"PeriodicalIF":2.0,"publicationDate":"2025-03-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143620122","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Aline Martins Candido de Oliveira, Luigi Lucas Rentes, Rodrigo dos Santos Pereira, Fabrizio Albieri
{"title":"Use of sclerosant solution for treatment of intraoral hemangioma: a case report","authors":"Aline Martins Candido de Oliveira, Luigi Lucas Rentes, Rodrigo dos Santos Pereira, Fabrizio Albieri","doi":"10.1016/j.oooo.2025.01.022","DOIUrl":"10.1016/j.oooo.2025.01.022","url":null,"abstract":"<div><div>Hemangioma is considered the most common benign vascular tumor during childhood, primarily affecting fair-skinned female patients. The aim of this study is to describe a case of hemangioma in a 29-year-old male patient with fair skin, evolving over 8 years on the right lateral border of the tongue. The intraoral clinical examination revealed a purplish stain with increased volume. The diagnosis was made through diascopy, and the treatment elected was local infiltration of sclerosing solution Ethamoline oleate in association with dexamethasone. In this case, it is noteworthy to emphasize the importance of considering this entity in the differential diagnosis of indolent intraoral stains of some duration, and it is vital that dentists maintain a high degree of clinical attention, given its potential for malignancy.</div></div>","PeriodicalId":49010,"journal":{"name":"Oral Surgery Oral Medicine Oral Pathology Oral Radiology","volume":"139 5","pages":"Page e4"},"PeriodicalIF":2.0,"publicationDate":"2025-03-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143620123","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Reuber Mendes Rocha, Alessah Carolyna de Andrade Fernandes, Angela Natalia Garnica Hilarión, Eleazar Mezaiko, Larissa Rosa Santana Rodrigues, Fernanda Paula Yamamoto-Silva, Brunno Santos de Freitas Silva
{"title":"Mandibular venolymphatic malformation identified with infrared thermography: a case report","authors":"Reuber Mendes Rocha, Alessah Carolyna de Andrade Fernandes, Angela Natalia Garnica Hilarión, Eleazar Mezaiko, Larissa Rosa Santana Rodrigues, Fernanda Paula Yamamoto-Silva, Brunno Santos de Freitas Silva","doi":"10.1016/j.oooo.2025.01.025","DOIUrl":"10.1016/j.oooo.2025.01.025","url":null,"abstract":"<div><div>This report describes an unusual case of venolymphatic malformation in the left mandibular angle of a 38-year-old male. The patient sought specialized attention due to a “facial growth upon physical exertion,” present for 2 years, painless, and static. During periods of rest, there was no facial asymmetry, but exertion revealed a normochromic, elastic, well-defined volumetric increase in the left mandible. Initially, ambulatory thermographic imaging was performed using an infrared thermography device, which showed a significant temperature alteration in that region after exertion. Magnetic resonance imaging confirmed an infiltrative lesion in the left masseter muscle, with subcutaneous extension and possible venous origin. The clinical diagnosis of venolymphatic malformation was established, and the patient was referred for follow-up with a vascular surgeon, remaining stable for the past 12 months. This report suggests that infrared thermography may represent an important adjunct in the diagnosis of maxillofacial vascular lesions.</div></div>","PeriodicalId":49010,"journal":{"name":"Oral Surgery Oral Medicine Oral Pathology Oral Radiology","volume":"139 5","pages":"Page e4"},"PeriodicalIF":2.0,"publicationDate":"2025-03-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143620126","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Larissa Santos Amaral Rolim, Helder Domiciano Dantas Martins, Eduarda Gomes Onofre de Araújo, Keila Martha Amorim Barroso, Ana Carolina Lyra de Albuquerque, Alexandre Rolim da Paz, Paulo Rogério Ferreti Bonan
{"title":"Multisystemic presentation of langerhans cell histiocytosis in pediatric patient: a case report of letterer-siwe disease","authors":"Larissa Santos Amaral Rolim, Helder Domiciano Dantas Martins, Eduarda Gomes Onofre de Araújo, Keila Martha Amorim Barroso, Ana Carolina Lyra de Albuquerque, Alexandre Rolim da Paz, Paulo Rogério Ferreti Bonan","doi":"10.1016/j.oooo.2025.01.008","DOIUrl":"10.1016/j.oooo.2025.01.008","url":null,"abstract":"<div><div>Letterer-Siwe disease is the most common and serious of these entities, affecting mainly infants up to 2 years of age. Here we report a case affecting a 1-year-old white male, presented with a complaint of nonhealing gingival lesion. Medical history revealed a supposed milk protein allergy, gastric reflux, anorexia, recent fever, and seborrheic dermatitis. On extraoral physical examination, palpable bilateral anterior and postauricular cervical lymph nodes were noted, along with abdominal distension, fever, and seborrheic dermatitis. Intraoral examination revealed bilateral gingival enlargement in the posterior tooth region. Subsequently, an incisional biopsy of the gingival lesion revealed ulcerative areas with intense mixed inflammatory infiltrate. Immunohistochemical evaluation confirmed positivity for CD1a, CD68, S100, Myeloperoxidase, CD20, and CD3, confirming the diagnosis of Langerhans cell histiocytosis. Due to multisystemic presentation, the diagnosis of Letterer-Siwe disease was confirmed, and the patient was referred for chemotherapeutic treatment under follow-up.</div></div>","PeriodicalId":49010,"journal":{"name":"Oral Surgery Oral Medicine Oral Pathology Oral Radiology","volume":"139 5","pages":"Page e1"},"PeriodicalIF":2.0,"publicationDate":"2025-03-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143620174","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Liliana Wolf Braun, Luiza Deitos Menti, Ana Sofia Rabello Fagherazzi, Luis Afonso Tochetto, Marco Antônio Trevizani Martins, Vinicius Coelho Carrard, Manoela Domingues Martins
{"title":"Oral granulocytic sarcoma as first sign of acute myeloid leukemia: a case report","authors":"Liliana Wolf Braun, Luiza Deitos Menti, Ana Sofia Rabello Fagherazzi, Luis Afonso Tochetto, Marco Antônio Trevizani Martins, Vinicius Coelho Carrard, Manoela Domingues Martins","doi":"10.1016/j.oooo.2025.01.010","DOIUrl":"10.1016/j.oooo.2025.01.010","url":null,"abstract":"<div><div>A 79-year-old male presented with asymptomatic gingival swelling that had developed over 1 month, referred by a dermatologist. The patient's medical history included hypertension, diabetes, treated lung and intestinal cancers, multiple basal cell carcinomas, and peripheral arterial diseases. He was a polypharmacy patient and a former smoker. Examination revealed left hemi-maxillary swelling with normochromic color and firm nodules of generalized gingiva extending to the hard palate associated with extraoral swelling. In addition, a firm left cervical lymph node was observed. Cranial computed tomography (CT) showed an infiltrative lesion with osteolysis. The leukogram, requested preoperatively for an oral biopsy, indicated an increase in the blast count, suggesting a hematological neoplasm. The patient was admitted for investigation, and an incisional biopsy confirmed granulocytic sarcoma. Furthermore, bone marrow biopsy and immunophenotyping revealed acute myeloid leukemia FLT3 positivity. Hematology physicians have proposed chemotherapy combined with radiotherapy. Unfortunately, the patient died 4 months postdiagnosis.</div></div>","PeriodicalId":49010,"journal":{"name":"Oral Surgery Oral Medicine Oral Pathology Oral Radiology","volume":"139 5","pages":"Page e1"},"PeriodicalIF":2.0,"publicationDate":"2025-03-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143620176","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Chronic osteomyelitis: diagnosis, treatment and follow-up with cone beam computed tomography","authors":"Bruna Lara França Lima, Elton Gonçalves Zenóbio, Cláudia Cardoso, Flávio Ricardo Manzi","doi":"10.1016/j.oooo.2025.01.086","DOIUrl":"10.1016/j.oooo.2025.01.086","url":null,"abstract":"<div><div>Osteomyelitis is an inflammatory and infectious condition that can present challenges in diagnosis and treatment planning. The present study reports a clinical case of a patient who presented signs and symptoms compatible with mandibular osteonecrosis after tooth extraction. In addition to clinical examination and anamnesis, cone beam computed tomography and histopathological examinations were performed, which led to the diagnosis of secondary chronic osteomyelitis. The treatment was performed in a conservative approach, with the use of antibiotic therapy, selective surgical debridement and application of low-power laser. For follow-up, new CT scans were performed 30 and 90 days after the beginning of treatment. The images showed absence of periosteal reaction and areas of complete and partial bone formation within boundaries of the lesion. Clinically, there was complete repair of the soft tissue and no edema, secretion or fistula, showing the efficiency of the treatment.</div></div>","PeriodicalId":49010,"journal":{"name":"Oral Surgery Oral Medicine Oral Pathology Oral Radiology","volume":"139 5","pages":"Page e16"},"PeriodicalIF":2.0,"publicationDate":"2025-03-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143620707","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}