Oral Surgery Oral Medicine Oral Pathology Oral Radiology最新文献

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Epithelioid hemangioendothelioma of the oral cavity: case report 口腔上皮样血管内皮瘤1例
IF 2 3区 医学
Oral Surgery Oral Medicine Oral Pathology Oral Radiology Pub Date : 2025-03-14 DOI: 10.1016/j.oooo.2025.01.027
Lara Maria Alencar Ramos Innocentini, Isabella Cristine dos Santos, Ana Carolina Fragoso Motta, Hilton Marcos Alves Hicz, Alan Grupioni Lourenço, Joel Del Bel Padua, Leandro Dorigan de Macedo
{"title":"Epithelioid hemangioendothelioma of the oral cavity: case report","authors":"Lara Maria Alencar Ramos Innocentini,&nbsp;Isabella Cristine dos Santos,&nbsp;Ana Carolina Fragoso Motta,&nbsp;Hilton Marcos Alves Hicz,&nbsp;Alan Grupioni Lourenço,&nbsp;Joel Del Bel Padua,&nbsp;Leandro Dorigan de Macedo","doi":"10.1016/j.oooo.2025.01.027","DOIUrl":"10.1016/j.oooo.2025.01.027","url":null,"abstract":"<div><div>A 49-year-old female was referred to a stomatologist due to complaints of enlargement and pain associated with a vascular lesion that had been monitored for 2 years. Her medical history revealed no systemic diseases. During the intraoral examination, a blue-purplish nodule was observed on the oral mucosa of the right lower lip and exhibited a fibrous region upon palpation with 1.0 cm in its greatest dimension. An incisional biopsy was performed, and histopathological examination revealed the presence of cords or nests of polygonal to slightly spindled epithelioid cells, with the formation of intracytoplasmic lumina, surrounding small vessels with perineural infiltration. Immunohistochemistry markers were positive for CD34, CD31, factor VIII-related antigen (FVIIIRAg), FLI1, D2-40, and ERG, confirming the diagnosis of epithelioid hemangioendothelioma (EHE). The patient was referred to a head and neck surgeon for complete removal of the EHE. She has been under observation for 2 years with no signs of recurrence.</div></div>","PeriodicalId":49010,"journal":{"name":"Oral Surgery Oral Medicine Oral Pathology Oral Radiology","volume":"139 5","pages":"Page e5"},"PeriodicalIF":2.0,"publicationDate":"2025-03-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143620128","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Surgical excision of large myoepithelioma in the palate 上颚大肌上皮瘤的手术切除
IF 2 3区 医学
Oral Surgery Oral Medicine Oral Pathology Oral Radiology Pub Date : 2025-03-14 DOI: 10.1016/j.oooo.2025.01.032
Fernanda Luiza Araújo de Lima Castro, Henrique Bemfica de Faria Freitas, Sérgio Antonucci Amaral, Renata Gonçalves Resende, Maria Cássia Ferreira Aguiar, Patrícia Carlos Caldeira, Júlio César Tanos Lacerda
{"title":"Surgical excision of large myoepithelioma in the palate","authors":"Fernanda Luiza Araújo de Lima Castro,&nbsp;Henrique Bemfica de Faria Freitas,&nbsp;Sérgio Antonucci Amaral,&nbsp;Renata Gonçalves Resende,&nbsp;Maria Cássia Ferreira Aguiar,&nbsp;Patrícia Carlos Caldeira,&nbsp;Júlio César Tanos Lacerda","doi":"10.1016/j.oooo.2025.01.032","DOIUrl":"10.1016/j.oooo.2025.01.032","url":null,"abstract":"<div><div>A 30-year-old female presented to the hospital with an extensive tumoral lesion on the palate, with an evolution of 20 years, causing dysphagia and difficulty in speaking. Incisional biopsy revealed a fragment of nonencapsulated neoplasm with proliferation of myoepithelial cells, forming cellular cords. The cells had large and eosinophilic cytoplasm and rounded nuclei displaced to the periphery, configuring a plasmacytoid morphology. The stroma of the lesion was composed of fibrous connective tissue, sometimes with a myxomatous appearance. The diagnosis was compatible with myoepithelioma. She was submitted to surgery under general anesthesia for conservative surgical enucleation of the lesion. To cover the raw area, a double-layer acellular dermal matrix was used, composed of bovine collagen internally and silicone externally, which was removed 3 weeks after surgery. After removal, a granulation tissue was observed, later giving way to the epithelial tissue of the palate. The patient is on regular follow-up with no abnormalities.</div></div>","PeriodicalId":49010,"journal":{"name":"Oral Surgery Oral Medicine Oral Pathology Oral Radiology","volume":"139 5","pages":"Page e6"},"PeriodicalIF":2.0,"publicationDate":"2025-03-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143620135","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Oral low-grade fibromyxoid sarcoma: a case report 口腔低级别纤维黏液样肉瘤1例
IF 2 3区 医学
Oral Surgery Oral Medicine Oral Pathology Oral Radiology Pub Date : 2025-03-14 DOI: 10.1016/j.oooo.2025.01.007
Cleiton Rone dos Santos Lima, Victor Hugo Lopes de Oliveira Moreira, Victor de Paula Coelho, Bruno Miranda Silva Lima, Elismauro Francisco de Mendonça, Diego Antonio Costa Arantes
{"title":"Oral low-grade fibromyxoid sarcoma: a case report","authors":"Cleiton Rone dos Santos Lima,&nbsp;Victor Hugo Lopes de Oliveira Moreira,&nbsp;Victor de Paula Coelho,&nbsp;Bruno Miranda Silva Lima,&nbsp;Elismauro Francisco de Mendonça,&nbsp;Diego Antonio Costa Arantes","doi":"10.1016/j.oooo.2025.01.007","DOIUrl":"10.1016/j.oooo.2025.01.007","url":null,"abstract":"<div><div>Low-grade fibromyxoid sarcoma is a rare malignant neoplasm of fibroblastic/myofibroblastic origin in the head and neck region. This lesion often arises in deep soft tissues with the potential for recurrence and late metastatic dissemination. A 23-year-old woman presented with a symptomatic swelling in the left posterior maxilla, evolving over 2 months, with an erythematous, ulcerated surface and evident telangiectasia. Computed tomography showed a hypodense osteolytic lesion located between tooth 27 and the maxillary tuberosity, with undefined borders and involvement of the left maxillary sinus. An incisional biopsy was performed, and histological analysis revealed a fibromyxoid neoplasm. Immunohistochemical staining was positive for AML, SATB2, Vimentin, and negative for SOX10, CD34, S100, Desmin. Considering both analyses, the final microscopic diagnosis was low-grade fibromyxoid sarcoma. The patient underwent surgical removal of the lesion, and after 12 months of clinical and radiographic follow-up, there are no signs of recurrence.</div></div>","PeriodicalId":49010,"journal":{"name":"Oral Surgery Oral Medicine Oral Pathology Oral Radiology","volume":"139 5","pages":"Page e1"},"PeriodicalIF":2.0,"publicationDate":"2025-03-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143620173","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Primordial cystic odontoma: a rare case associated with aborted tooth 原始囊性齿瘤:一例罕见的与流产牙相关的病例
IF 2 3区 医学
Oral Surgery Oral Medicine Oral Pathology Oral Radiology Pub Date : 2025-03-14 DOI: 10.1016/j.oooo.2025.01.009
Ana Luiza Oliveira Corrêa Roza, Stephanie Vargas de Freitas, Roberto Prado, Paula Paiva do Nascimento Izquierdo, Michelle Agostini, Aline Corrêa Abrahão, Mario José Romañach
{"title":"Primordial cystic odontoma: a rare case associated with aborted tooth","authors":"Ana Luiza Oliveira Corrêa Roza,&nbsp;Stephanie Vargas de Freitas,&nbsp;Roberto Prado,&nbsp;Paula Paiva do Nascimento Izquierdo,&nbsp;Michelle Agostini,&nbsp;Aline Corrêa Abrahão,&nbsp;Mario José Romañach","doi":"10.1016/j.oooo.2025.01.009","DOIUrl":"10.1016/j.oooo.2025.01.009","url":null,"abstract":"<div><div>An otherwise healthy 12-year-old girl was referred for evaluation upon an incidental radiographic finding during orthodontic treatment planning. Imaging exams revealed a 20 mm well-defined unilocular radiolucency containing a delicate peripheral radiopaque rim, closely related to the unformed crown of the lower third molar germ. An excisional biopsy was performed under local anesthesia. Grossly, a 10 mm fragment of a tooth germ was accompanied by a 10 mm round whitish mass of hard consistency and cystic eggshell appearance on the cut surface. Microscopic evaluation revealed a cyst lined by ameloblastic epithelium, surrounded by an outer layer of mineralized dentin and primitive dental papilla-like ectomesenchyme. The tooth germ revealed features consistent with an aberrant odontogenic process. The final diagnosis was primordial cystic odontoma (PCO) associated with an aborted third molar. We report an additional illustrative case of PCO, an ill-defined entity that should not be misinterpreted as other odontogenic lesions.</div></div>","PeriodicalId":49010,"journal":{"name":"Oral Surgery Oral Medicine Oral Pathology Oral Radiology","volume":"139 5","pages":"Page e1"},"PeriodicalIF":2.0,"publicationDate":"2025-03-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143620175","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A mass in the tongue of an 11-month-old baby 一个11个月大的婴儿舌头上的肿块
IF 2 3区 医学
Oral Surgery Oral Medicine Oral Pathology Oral Radiology Pub Date : 2025-03-14 DOI: 10.1016/j.oooo.2025.01.011
Isadora Pereira Gomes, Nathalia Rodrigues Gomes, Henrique Bemfica de Freitas Faria, Renata Gonçalves de Resende, Júlio César Tanos de Lacerda, Ricardo Alves de Mesquita, Ricardo Santiago Gomez
{"title":"A mass in the tongue of an 11-month-old baby","authors":"Isadora Pereira Gomes,&nbsp;Nathalia Rodrigues Gomes,&nbsp;Henrique Bemfica de Freitas Faria,&nbsp;Renata Gonçalves de Resende,&nbsp;Júlio César Tanos de Lacerda,&nbsp;Ricardo Alves de Mesquita,&nbsp;Ricardo Santiago Gomez","doi":"10.1016/j.oooo.2025.01.011","DOIUrl":"10.1016/j.oooo.2025.01.011","url":null,"abstract":"<div><div>An 11-month-old baby presented at the stomatology service with a tumor growth located in the tongue dorsum, which had been evolving for 10 months. Suspecting a congenital malformation, the lesion was surgically excised and sent for histopathological analysis. Microscopic examination revealed a mass characterized by the proliferation of mature neuroglial tissue interwoven with a homogeneous eosinophilic stroma, extending deeply into the tongue muscle. Many astrocytes, microglial cells, and oligodendrocytes were present. Immunohistochemical staining for GFAP, S-100, and vimentin showed strong positivity, while AML was also positive, and the ki67 proliferation index was &lt;1% in the neuroglial tissue. With these findings, the final diagnosis was of glial choristoma.</div></div>","PeriodicalId":49010,"journal":{"name":"Oral Surgery Oral Medicine Oral Pathology Oral Radiology","volume":"139 5","pages":"Pages e1-e2"},"PeriodicalIF":2.0,"publicationDate":"2025-03-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143620177","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Simultaneous presentation of peripheral ossifying fibroma and pyogenic granuloma: a case report 同时表现为周围骨化性纤维瘤和化脓性肉芽肿1例
IF 2 3区 医学
Oral Surgery Oral Medicine Oral Pathology Oral Radiology Pub Date : 2025-03-14 DOI: 10.1016/j.oooo.2025.01.087
Michele Di Benedetto, Lukas Mendes de Abreu, Kaique Alberto Preto, Raquel Molina Sanches, Vanessa Soares Lara, Paulo Sérgio da Silva Santos, Cássia Maria Fischer Rubira
{"title":"Simultaneous presentation of peripheral ossifying fibroma and pyogenic granuloma: a case report","authors":"Michele Di Benedetto,&nbsp;Lukas Mendes de Abreu,&nbsp;Kaique Alberto Preto,&nbsp;Raquel Molina Sanches,&nbsp;Vanessa Soares Lara,&nbsp;Paulo Sérgio da Silva Santos,&nbsp;Cássia Maria Fischer Rubira","doi":"10.1016/j.oooo.2025.01.087","DOIUrl":"10.1016/j.oooo.2025.01.087","url":null,"abstract":"<div><div>Peripheral Ossifying Fibroma (POF) and Pyogenic Granuloma (PG) are common reactive lesions in the oral cavity, presenting distinct histomorphological characteristics. We report a case of a 54-year-old female patient with a singular lesion on the left posterior gingiva of the mandible. The lesion had been evolving for 8 months and presented painful symptoms. Excisional biopsy was performed, and histopathological analysis revealed fibrous connective tissue with high cellularity, spindle-shaped cells, and mineralized tissue resembling trabecular bone, alongside indications of chronic periodontal inflammation and granulation tissue. The diagnosis was peripheral ossifying fibroma associated with pyogenic granuloma and chronic inflammatory periodontal disease. Such concurrent occurrence and interrelation are rarely documented in the literature. This case underscores the significance of accurate differential diagnosis and understanding the etiopathogenic foundations of these lesions to ensure proper clinical management.</div></div>","PeriodicalId":49010,"journal":{"name":"Oral Surgery Oral Medicine Oral Pathology Oral Radiology","volume":"139 5","pages":"Pages e16-e17"},"PeriodicalIF":2.0,"publicationDate":"2025-03-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143620708","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Aspergillosis in an immunocompromised patient with acute myelomonocytic leukemia 急性髓细胞白血病免疫功能低下患者的曲霉病
IF 2 3区 医学
Oral Surgery Oral Medicine Oral Pathology Oral Radiology Pub Date : 2025-03-14 DOI: 10.1016/j.oooo.2025.01.077
Beatriz Bastos Macêdo, Liciane Mariano dos Santos Menezes, Maria Eduarda Haerdy Monteiro, Edval Reginaldo Tenório Júnios, Viviane Almeida Sarmento, Patrícia Miranda Leite Ribeiro, Liliane Lins-Kusterer
{"title":"Aspergillosis in an immunocompromised patient with acute myelomonocytic leukemia","authors":"Beatriz Bastos Macêdo,&nbsp;Liciane Mariano dos Santos Menezes,&nbsp;Maria Eduarda Haerdy Monteiro,&nbsp;Edval Reginaldo Tenório Júnios,&nbsp;Viviane Almeida Sarmento,&nbsp;Patrícia Miranda Leite Ribeiro,&nbsp;Liliane Lins-Kusterer","doi":"10.1016/j.oooo.2025.01.077","DOIUrl":"10.1016/j.oooo.2025.01.077","url":null,"abstract":"<div><div>Aspergillosis is an opportunistic fungal disease that manifests in immunocompromised individuals and has a high associated mortality. A 33-year-old male patient diagnosed with acute myelomonocytic leukemia during hospitalization started chemotherapy and at D20 of the patient cycle evolved with a black lesion in the hard palate, associated with facial edema, perforation in the palate and severe dental mobility in the maxilla. Biopsy and culture of the removed fragments were performed. The histopathological report of the collected fragments included findings of hyphae suggestive of aspergillosis. The patient reported nosebleeds and rhinorrhea, in addition to hearing loss, and is being monitored with voriconazole medication and is preparing for surgery and a new cycle of chemotherapy. The case demonstrates the importance of clinical follow-up of patients undergoing cancer treatment for early diagnosis of infectious advents.</div></div>","PeriodicalId":49010,"journal":{"name":"Oral Surgery Oral Medicine Oral Pathology Oral Radiology","volume":"139 5","pages":"Page e15"},"PeriodicalIF":2.0,"publicationDate":"2025-03-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143620822","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Bilateral mandibular juvenile ossifying trabecular fibroma in a pediatric patient: a case report of a rare entity 小儿双侧青少年下颌骨骨化小梁纤维瘤1例:罕见病例报告
IF 2 3区 医学
Oral Surgery Oral Medicine Oral Pathology Oral Radiology Pub Date : 2025-03-14 DOI: 10.1016/j.oooo.2025.01.046
Maria Paula Novaes Camargo Manna, Yuri de Lima Medeiros, Lívia Marquesdos Santos, Zarife Tirapani Adum Resende, Priscila Faquini Macedo, Bruno Augusto Benevenuto de Andrade, Daniel Amaral Alves Marlière
{"title":"Bilateral mandibular juvenile ossifying trabecular fibroma in a pediatric patient: a case report of a rare entity","authors":"Maria Paula Novaes Camargo Manna,&nbsp;Yuri de Lima Medeiros,&nbsp;Lívia Marquesdos Santos, Zarife Tirapani Adum Resende,&nbsp;Priscila Faquini Macedo,&nbsp;Bruno Augusto Benevenuto de Andrade,&nbsp;Daniel Amaral Alves Marlière","doi":"10.1016/j.oooo.2025.01.046","DOIUrl":"10.1016/j.oooo.2025.01.046","url":null,"abstract":"<div><div>The purpose of this study was to report a rare case of bilateral mandibular trabecular juvenile ossifying fibroma (TJOF) in a pediatric patient. A 13-year-old male patient presented to the dentist with swelling of the right face. Cone beam computed tomography revealed hypodense areas associated with hyperdense islands and expansion of the cortical bone in the bilateral posterior mandibles. An incisional biopsy was performed. Histologic analysis revealed irregular trabeculae of immature bone and calcified bone structures in a hypercellular stroma with spindle cells. The cells were immunopositive for the SATB2 marker and negative for AE1/AE3 cytokeratin. The final diagnosis was TJOF. Enucleation, curettage, and peripheral osteotomy using a rapid prototyping biomodel of the tumors were performed. At the 12-month follow-up, a left-sided recurrence was noted, and another surgical approach was performed. Postoperative tomographic images suggested appropriate healing at the 24-month follow-up, demonstrating complete removal of the tumor.</div></div>","PeriodicalId":49010,"journal":{"name":"Oral Surgery Oral Medicine Oral Pathology Oral Radiology","volume":"139 5","pages":"Page e9"},"PeriodicalIF":2.0,"publicationDate":"2025-03-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143620012","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Rapidly growing pediatric rhabdomyosarcoma: clinical, tomographic and histological aspects 快速生长的小儿横纹肌肉瘤:临床、断层和组织学方面
IF 2 3区 医学
Oral Surgery Oral Medicine Oral Pathology Oral Radiology Pub Date : 2025-03-14 DOI: 10.1016/j.oooo.2025.01.039
Livian Isabel de Medeiros Carvalho, Eduarda Gomes Onofre de Araújo, Hélder Domiciano Dantas Martins, Keila Martha Amorim Barroso, Amanda Maria Medeiros de Araújo Luck, Alexandre Rolim de Paz, Paulo Rogério Ferreti Bonan
{"title":"Rapidly growing pediatric rhabdomyosarcoma: clinical, tomographic and histological aspects","authors":"Livian Isabel de Medeiros Carvalho,&nbsp;Eduarda Gomes Onofre de Araújo,&nbsp;Hélder Domiciano Dantas Martins,&nbsp;Keila Martha Amorim Barroso,&nbsp;Amanda Maria Medeiros de Araújo Luck,&nbsp;Alexandre Rolim de Paz,&nbsp;Paulo Rogério Ferreti Bonan","doi":"10.1016/j.oooo.2025.01.039","DOIUrl":"10.1016/j.oooo.2025.01.039","url":null,"abstract":"<div><div>An 8-year-old female exhibited swelling after a tooth extraction, prompted by severe mobility of deciduous teeth and a tissue mass. The extraoral examination displayed significant swelling on the right side of the face, causing noticeable asymmetry. An intraoral examination uncovered a lobulated, erythematous tumor-like lesion. Panoramic radiography showed a radiolucent area in the right maxillary region, indicating a “floating teeth” pattern and root resorption. Computed tomography revealed an ill-defined hypodense mass extending to the orbit, nasal fossa, and right maxillary sinus. An incisional biopsy identified a proliferation of atypical round and spindle cells within a variably myxoid or fibrous stroma. Immunohistochemistry tests for desmin, myogenin, and the MYOD1 gene were positive, confirming a diagnosis of rhabdomyosarcoma. Following the diagnosis, the patient underwent radiotherapy and chemotherapy. Eight months into treatment, there has been no recurrence of the lesion, and she remains under careful observation.</div></div>","PeriodicalId":49010,"journal":{"name":"Oral Surgery Oral Medicine Oral Pathology Oral Radiology","volume":"139 5","pages":"Page e7"},"PeriodicalIF":2.0,"publicationDate":"2025-03-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143619993","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Management of medication-induced gingival overgrowth in a hypertensive patient: a case report 高血压患者药物性牙龈增生的处理:1例报告
IF 2 3区 医学
Oral Surgery Oral Medicine Oral Pathology Oral Radiology Pub Date : 2025-03-14 DOI: 10.1016/j.oooo.2025.01.041
Leticia Beatriz da Cruz Santos, Amanda Feitoza da Silva, Claudia Rebecca Costa Cavalcante Silva, Matheus Santos Mafra Barbosa, Mariana Bitu Ramos-Pinto, Lais Christina Pontes de Espindola, Thalwylla Reiler Moratodos Reis Moreira
{"title":"Management of medication-induced gingival overgrowth in a hypertensive patient: a case report","authors":"Leticia Beatriz da Cruz Santos,&nbsp;Amanda Feitoza da Silva,&nbsp;Claudia Rebecca Costa Cavalcante Silva,&nbsp;Matheus Santos Mafra Barbosa,&nbsp;Mariana Bitu Ramos-Pinto,&nbsp;Lais Christina Pontes de Espindola,&nbsp;Thalwylla Reiler Moratodos Reis Moreira","doi":"10.1016/j.oooo.2025.01.041","DOIUrl":"10.1016/j.oooo.2025.01.041","url":null,"abstract":"<div><div>Gingival overgrowth can arise from inflammatory factors related to biofilm or specific medications, including anticonvulsants, immunosuppressants, and calcium channel blockers. We present a case of medication-induced gingival overgrowth associated with amlodipine. A 40-year-old male patient presented with complaints of altered gingival contour after 8 months of initiating amlodipine treatment for hypertension. Upon clinical examination, increased growth of gingival interdental papillae was observed, along with the presence of pseudopockets upon periodontal probing. Initial periodontal treatment was followed by gingivectomy and gingivoplasty. Post-treatment, the patient was referred to a cardiologist to evaluate the possibility of changing medication to prevent recurrence. After 60 days of follow-up, the periodontal condition was deemed satisfactory. Medication-induced gingival overgrowth is a common adverse effect in certain medication groups, and gingival plastic surgery may be necessary to restore physiological gingival contour, thereby improving patient function and aesthetics.</div></div>","PeriodicalId":49010,"journal":{"name":"Oral Surgery Oral Medicine Oral Pathology Oral Radiology","volume":"139 5","pages":"Page e8"},"PeriodicalIF":2.0,"publicationDate":"2025-03-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143619995","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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