上皮样肉瘤转移到口腔

IF 1.9 3区医学 Q2 DENTISTRY, ORAL SURGERY & MEDICINE

Oral Surgery Oral Medicine Oral Pathology Oral Radiology Pub Date : 2025-07-21 DOI:10.1016/j.oooo.2025.04.044

Khanh Trinh, Elizabeth Philipone

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引用次数: 0

摘要

上皮样肉瘤（ES）是一种罕见的间质恶性肿瘤，由Enzinger于1970年首次描述。该实体以其临床侵袭性行为和整体预后不良而闻名。ES通常出现在青少年和年轻人的四肢，在头颈部，尤其是口腔极为罕见。我们报告一例上皮样肉瘤转移到口腔（上颌牙龈和下颌骨）。肿瘤主要由上皮样细胞和分散的梭形细胞组成。这两个群体的细胞都表现出色素增多和多形性。肿瘤细胞MCK、CK8、EMA、vimentin、CD34呈阳性，S100、CD45、CD31呈阴性。

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Epithelioid sarcoma metastasis to the oral cavity

Epithelioid sarcoma (ES) is a rare malignant neoplasm of mesenchymal origin first described by Enzinger in 1970. This entity is known for its clinical aggressive behavior and overall poor prognosis. ES often presents in the extremities of adolescents and young adults and is exceedingly rare in the head and neck region, especially the oral cavity. We present a case of epithelioid sarcoma with metastasis to the oral cavity (maxillary gingiva and mandible). The tumor is composed of predominantly epithelioid cells admixed with scattered spindle cells. Both populations of cells display hyperchromasia and pleomorphism. The tumor cells are positive for MCK, CK8, EMA, vimentin, CD34, and negative for S100, CD45, and CD31.

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来源期刊

Oral Surgery Oral Medicine Oral Pathology Oral Radiology DENTISTRY, ORAL SURGERY & MEDICINE-

CiteScore

3.80

自引率

6.90%

发文量

1217

审稿时长

2-4 weeks

期刊介绍： Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology is required reading for anyone in the fields of oral surgery, oral medicine, oral pathology, oral radiology or advanced general practice dentistry. It is the only major dental journal that provides a practical and complete overview of the medical and surgical techniques of dental practice in four areas. Topics covered include such current issues as dental implants, treatment of HIV-infected patients, and evaluation and treatment of TMJ disorders. The official publication for nine societies, the Journal is recommended for initial purchase in the Brandon Hill study, Selected List of Books and Journals for the Small Medical Library.