International Journal of Biomedical Imaging最新文献

{"title":"Brain Tumour Detection Using VGG-Based Feature Extraction With Modified DarkNet-53 Model.","authors":"S Trisheela, Roshan Fernandes, Anisha P Rodrigues, S Supreeth, B J Ambika, Piyush Kumar Pareek, Rakesh Kumar Godi, G Shruthi","doi":"10.1155/ijbi/5535505","DOIUrl":"10.1155/ijbi/5535505","url":null,"abstract":"<p><p>The objective of AI research and development is to create intelligent systems capable of performing tasks and reasoning like humans. Artificial intelligence extends beyond pattern recognition, planning, and problem-solving, particularly in the realm of machine learning, where deep learning frameworks play a pivotal role. This study focuses on enhancing brain tumour detection in MRI scans using deep learning techniques. Malignant brain tumours result from abnormal cell growth, leading to severe neurological complications and high mortality rates. Early diagnosis is essential for effective treatment, and our research aims to improve detection accuracy through advanced AI methodologies. We propose a modified DarkNet-53 architecture, optimized with invasive weed optimization (IWO), to extract critical features from preprocessed MRI images. The model's presentation is assessed using accuracy, recall, loss, and AUC, achieving a 95% success rate on a dataset of 3264 MRI scans. The results demonstrate that our approach surpasses existing methods in accurately identifying a wide range of brain tumours at an early stage, contributing to improved diagnostic precision and patient outcomes.</p>","PeriodicalId":47063,"journal":{"name":"International Journal of Biomedical Imaging","volume":"2025 ","pages":"5535505"},"PeriodicalIF":3.3,"publicationDate":"2025-05-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12143945/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144250254","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Analysis of the Effect of Antenna-to-Head Distance for Microwave Brain Imaging Applications.","authors":"Farhana Parveen, Parveen Wahid","doi":"10.1155/ijbi/8872566","DOIUrl":"https://doi.org/10.1155/ijbi/8872566","url":null,"abstract":"<p><p>Wideband antennas are extensively used in many medical applications, which require the placement of the antenna on or near a human body. The performance of the antenna should remain compliant with the requirements of the target application when placed in front of the subject under investigation. Since the performance of an antenna varies when the distance from the subject is changed, the effect of varying the distance of a miniaturized wideband antipodal Vivaldi antenna from a numerical head model is analyzed in this work. The analyses can demonstrate whether the antenna performance and its effect on the head aptly comply with the requirements for the intended application of microwave brain imaging. It is observed that, when the antenna-head distance is increased, the background noise in the received signal is enhanced, whereas when the distance is reduced, the radiation-safety consideration on the head is affected. Hence, the optimum distance should provide a good compromise in terms of both signal receptibility by the antenna and radiation safety on the head. As the optimum antenna-to-head distance may vary with the change in antenna, measurement system, and the surrounding medium, this work presents a basic analysis procedure to find the appropriate antenna distance for the intended application.</p>","PeriodicalId":47063,"journal":{"name":"International Journal of Biomedical Imaging","volume":"2025 ","pages":"8872566"},"PeriodicalIF":3.3,"publicationDate":"2025-05-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12066184/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144006452","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Assessments of Medical Student's Knowledge About Radiation Protection and Different Imaging Modalities in Jeddah, Saudi Arabia.","authors":"Raghad Aljondi, Rahaf Alem, Rowa Aljondi, Abdulrahman Tajaldeen, Salem Saeed Alghamdi, Mohammed Majdi Toras","doi":"10.1155/ijbi/1528291","DOIUrl":"https://doi.org/10.1155/ijbi/1528291","url":null,"abstract":"<p><p><b>Introduction:</b> Doctors can play a significant role in attributing to patient safety concerning exposure to ionizing radiation. Therefore, healthcare professionals should have adequate knowledge about radiation risk and protection of different medical imaging examinations. This study aims to evaluate the knowledge about radiation protection (RP) and applications of different imaging modalities (IMs) among medical students in their clinical years and intern, in Jeddah, Saudi Arabia. <b>Materials and Methods:</b> A cross-sectional study based on an online questionnaire was performed in Jeddah, Saudi Arabia, on 170 medical students during January 2024; the study participants included clinical years medical students (from Years 4 to 6) and interns of both gender and basic year medical students, and specialists and consultants were excluded. For each participant, the percentage of correct answers was calculated for the knowledge RP and knowledge in IMs separately, and each participant will have two scores, RP knowledge score (RPKS) and IM knowledge score (IMKS). <b>Results:</b> A total of 170 medical students responded and completed the questionnaire. The overall levels of awareness and knowledge of the students was determined through calculations of their scores in answering the questionnaire; students in this study group have low average knowledge score in RP, which is 43, while they have moderate-high knowledge score in IMs, which is 68. Regarding the knowledge score, for the RPKS, the best participant scored 82, while the worst scored 0, whereas for IMKS, the best participant score 100, while the worst scored 0. However, according to the SD, participants generally differ between each other by 19 in RPKS and 31 in IMKS. <b>Conclusions:</b> The assessments of medical students' knowledge regarding radiation exposure in diagnostic modalities reveal a low level of confidence in their knowledge of ionizing radiation dose parameters. Furthermore, the mean scores on overall knowledge assessments indicate a need for improvement in RP knowledge for medical students. To address this gap, a comprehensive modification of the undergraduate medical curriculum's radiology component is required by enhancing active learning approaches and integrating radiation safety courses early in the medical curriculum. Medical education institutions could implement ongoing workshops, online modules, and certification programs to reinforce radiation safety principles.</p>","PeriodicalId":47063,"journal":{"name":"International Journal of Biomedical Imaging","volume":"2025 ","pages":"1528291"},"PeriodicalIF":3.3,"publicationDate":"2025-04-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12045688/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143989135","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparison of Anatomical and Indication-Based Diagnostic Reference Levels (DRLs) in Head CT Imaging: Implications for Radiation Dose Management.","authors":"Benard Ohene-Botwe, Samuel Anim-Sampong, Robert Saizi","doi":"10.1155/ijbi/6464273","DOIUrl":"10.1155/ijbi/6464273","url":null,"abstract":"<p><p><b>Introduction:</b> Many diagnostic reference levels (DRLs) in computed tomography (CT) imaging are based mainly on anatomical locations and often overlook variations in radiation exposure due to different clinical indications. While indication-based DRLs, derived from dose descriptors like volume-weighted CT dose index (CTDI_vol) and dose length product (DLP), are recommended for optimising patient radiation exposure, many studies still use anatomical-based DRL values. This study is aimed at quantifying the differences between anatomical and indication-based DRL values in head CT imaging and assessing its implications for radiation dose management. This will support the narrative when explaining the distinction between indication-based DRLs and anatomical DRLs for patients' dose management. <b>Methods:</b> Employing a retrospective quantitative study design, we developed and compared anatomical and common indication-based DRL values using a dataset of head CT scans with similar characteristics. The indications included in the study were brain tumor/intracranial space-occupying lesion (ISOL), head injury/trauma, stroke, and anatomical examinations. Data analysis was conducted using SPSS Version 29. <b>Results:</b> The findings suggest that using anatomical-based DLP DRL values for CT head examinations leads to underestimations in the median, 25th percentile, and 75th percentile values of head injury/trauma by 20.2%, 30.0%, and 14.5% in single-phase CT head procedures. Conversely, for the entire examination, using anatomical-based DLP DRL as a benchmark for CT stroke DRL overestimates median, 25th percentile, and 75th percentile values by 18.3%, 23.9%, and 13.5%. Brain tumor/ISOL DL<i>P</i> values are underestimated by 62.6%, 60.4%, and 71.8%, respectively. <b>Conclusion:</b>The study highlights that using anatomical DLP DRL values for specific indications in head CT scans can lead to underestimated or overestimated DL<i>P</i> values, making them less reliable for radiation management compared to indication-based DRLs. Therefore, it is imperative to promote the establishment and use of indication-based DRLs for more accurate dose management in CT imaging.</p>","PeriodicalId":47063,"journal":{"name":"International Journal of Biomedical Imaging","volume":"2025 ","pages":"6464273"},"PeriodicalIF":3.3,"publicationDate":"2025-03-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11944678/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143721830","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"CDSE-UNet: Enhancing COVID-19 CT Image Segmentation With Canny Edge Detection and Dual-Path SENet Feature Fusion.","authors":"Jiao Ding, Jie Chang, Renrui Han, Li Yang","doi":"10.1155/ijbi/9175473","DOIUrl":"10.1155/ijbi/9175473","url":null,"abstract":"<p><p>Accurate segmentation of COVID-19 CT images is crucial for reducing the severity and mortality rates associated with COVID-19 infections. In response to blurred boundaries and high variability characteristic of lesion areas in COVID-19 CT images, we introduce CDSE-UNet: a novel UNet-based segmentation model that integrates Canny operator edge detection and a Dual-Path SENet Feature Fusion Block (DSBlock). This model enhances the standard UNet architecture by employing the Canny operator for edge detection in sample images, paralleling this with a similar network structure for semantic feature extraction. A key innovation is the DSBlock, applied across corresponding network layers to effectively combine features from both image paths. Moreover, we have developed a Multiscale Convolution Block (MSCovBlock), replacing the standard convolution in UNet, to adapt to the varied lesion sizes and shapes. This addition not only aids in accurately classifying lesion edge pixels but also significantly improves channel differentiation and expands the capacity of the model. Our evaluations on public datasets demonstrate CDSE-UNet's superior performance over other leading models. Specifically, CDSE-UNet achieved an accuracy of 0.9929, a recall of 0.9604, a DSC of 0.9063, and an IoU of 0.8286, outperforming UNet, Attention-UNet, Trans-Unet, Swin-Unet, and Dense-UNet in these metrics.</p>","PeriodicalId":47063,"journal":{"name":"International Journal of Biomedical Imaging","volume":"2025 ","pages":"9175473"},"PeriodicalIF":3.3,"publicationDate":"2025-03-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11930385/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143693961","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cortical Morphology Alterations Mediate the Relationship Between Glymphatic System Function and the Severity of Asthenopia.","authors":"Yilei Chen, Jun Xu, Yingnan Kong, Yingjie Kang, Zhigang Gong, Hui Wang, Yanwen Huang, Songhua Zhan, Ying Yu, Xiaoli Lv, Wenli Tan","doi":"10.1155/ijbi/4464776","DOIUrl":"10.1155/ijbi/4464776","url":null,"abstract":"<p><p><b>Objectives</b>: This study is aimed at assessing glymphatic function by diffusion tensor image analysis along the perivascular space (DTI-ALPS) and its associations with cortical morphological changes and severity of accommodative asthenopia (AA). <b>Methods</b>: We prospectively enrolled 50 patients with AA and 47 healthy controls (HCs). All participants underwent diffusion tensor imaging (DTI) and T1-weighted imaging and completed the asthenopia survey scale (ASS). Differences in brain morphometry and the analysis along the perivascular space (ALPS) index between the two groups were compared. The correlation and mediation analyses were conducted to explore the relationships between them. <b>Results</b>: Compared to HCs, patients with AA exhibited significantly increased sulcal depth in the left superior occipital gyrus (SOG.L) and increased cortical thickness in the left superior temporal gyrus (STG.L), left middle occipital gyrus (MOG.L), left postcentral gyrus (PoCG.L), and left precuneus (PCUN.L). Additionally, patients with AA had a significantly lower ALPS index than HCs. The sulcal depth of the SOG.L was significantly positively correlated with the ASS score in patients with AA, and a positive correlation was found between the cortical thickness of the MOG.L and ASS score. The ALPS index was negatively associated with the sulcal depth of the SOG.L and cortical thickness of the MOG.L. Mediation analysis revealed that the sulcal depth of SOG.L and cortical thickness of MOG.L partially mediated the impact of the DTI-ALPS index on the ASS score. <b>Conclusion</b>: Our findings suggested that patients with AA exhibit impaired glymphatic function, which may contribute to the severity of asthenopia through its influence on cortical morphological changes. The ALPS index is anticipated to become a potential imaging biomarker for patients with AA. <b>Trial Registration:</b> Chinese Registry of Clinical Trials: ChiCTR1900028306.</p>","PeriodicalId":47063,"journal":{"name":"International Journal of Biomedical Imaging","volume":"2025 ","pages":"4464776"},"PeriodicalIF":3.3,"publicationDate":"2025-02-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11879604/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143558348","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Validity and Responsiveness of Measuring Facial Swelling With 3D Stereophotogrammetry in Patients After Bilateral Sagittal Split Osteotomy-A Prospective Clinimetric Study.","authors":"Margje B Buitenhuis, Reinoud J Klijn, Antoine J W P Rosenberg, Caroline M Speksnijder","doi":"10.1155/ijbi/9957797","DOIUrl":"10.1155/ijbi/9957797","url":null,"abstract":"<p><p><b>Introduction:</b> This study is aimed at determining the validity and responsiveness of three-dimensional (3D) stereophotogrammetry as a measurement instrument for evaluating soft tissue changes in the head and neck area. <b>Method:</b> Twelve patients received a bilateral sagittal split osteotomy (BSSO). 3D stereophotogrammetry, tape measurements, and a global perceived effect scale were performed within the first, second, and third postoperative weeks and at 3 months postoperatively. Distance measurements, mean and root mean square of the distance map, and volume differences were obtained from 3D stereophotogrammetry. Validity and responsiveness were assessed by correlation coefficients. <b>Results:</b> Significant correlations between distances from 3D stereophotogrammetry and tape measurements varied from 0.583 to 0.988, meaning moderate to very high validity. The highest correlations were found for the total sum of distances (<i>r</i> ≥ 0.922). 3D stereophotogrammetry parameters presented weak to high responsiveness, depending on the evaluated head and neck region. None of the parameters for 3D stereophotogrammetry significantly correlated with the global perceived effect scale outcomes for all measurement moments. <b>Conclusion:</b> 3D stereophotogrammetry has high to very high construct validity for the total sum of distances and weak to high responsiveness. 3D stereophotogrammetry seems promising for measuring soft tissue changes after surgery but is not interchangeable with subjective measurements.</p>","PeriodicalId":47063,"journal":{"name":"International Journal of Biomedical Imaging","volume":"2025 ","pages":"9957797"},"PeriodicalIF":3.3,"publicationDate":"2025-02-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11876518/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143558350","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Automatic Segmentation of the Cisternal Segment of Trigeminal Nerve on MRI Using Deep Learning.","authors":"Li-Ming Hsu, Shuai Wang, Sheng-Wei Chang, Yu-Li Lee, Jen-Tsung Yang, Ching-Po Lin, Yuan-Hsiung Tsai","doi":"10.1155/ijbi/6694599","DOIUrl":"10.1155/ijbi/6694599","url":null,"abstract":"<p><p><b>Purpose:</b> Accurate segmentation of the cisternal segment of the trigeminal nerve plays a critical role in identifying and treating different trigeminal nerve-related disorders, including trigeminal neuralgia (TN). However, the current manual segmentation process is prone to interobserver variability and consumes a significant amount of time. To overcome this challenge, we propose a deep learning-based approach, U-Net, that automatically segments the cisternal segment of the trigeminal nerve. <b>Methods:</b> To evaluate the efficacy of our proposed approach, the U-Net model was trained and validated on healthy control images and tested in on a separate dataset of TN patients. The methods such as Dice, Jaccard, positive predictive value (PPV), sensitivity (SEN), center-of-mass distance (CMD), and Hausdorff distance were used to assess segmentation performance. <b>Results:</b> Our approach achieved high accuracy in segmenting the cisternal segment of the trigeminal nerve, demonstrating robust performance and comparable results to those obtained by participating radiologists. <b>Conclusion:</b> The proposed deep learning-based approach, U-Net, shows promise in improving the accuracy and efficiency of segmenting the cisternal segment of the trigeminal nerve. To the best of our knowledge, this is the first fully automated segmentation method for the trigeminal nerve in anatomic MRI, and it has the potential to aid in the diagnosis and treatment of various trigeminal nerve-related disorders, such as TN.</p>","PeriodicalId":47063,"journal":{"name":"International Journal of Biomedical Imaging","volume":"2025 ","pages":"6694599"},"PeriodicalIF":3.3,"publicationDate":"2025-02-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11847612/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143484410","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Visualization of Small Vessels by Micro-Computed Tomography Using Titanium Dioxide Nanoparticles as a Novel Contrast Agent.","authors":"Taku Goto, Ruriko Tanabe, Hirotoshi Shibuya, Masaru Tamura, Shintaro Nomura","doi":"10.1155/ijbi/6688558","DOIUrl":"10.1155/ijbi/6688558","url":null,"abstract":"<p><p>Angiography by means of micro-computed tomography (m-CT) is extensively used for the diagnosis of vasculature disorders. To establish a connection between m-CT images and genuine histopathology findings, we developed two novel titanium dioxide nanoparticle (TiO₂-NP)-based perfusion contrast agents: TiNpCA-1 and TiNpCA-2. Three-dimensionally reconstructed m-CT images in mice perfused with these contrast agents showed high resolution and accuracy in various organs without deformation or dilation of vessels. Vessels < 20 <i> μ</i>m in diameter were clearly visualized by m-CT, and capillaries of 4 <i>μ</i>m in diameter were visualized by nano-CT. After perfusion, the contrast agents were kept in the vessels by the formation of an aggregate with ethanol. Histological samples were prepared from CT-scanned specimens. No perfusion-induced damage or abnormal structures were observed. The signals of the contrast agents were detected clearly, and the tissue histology was of adequate quality for pathological diagnosis. Agglomerates of TiO₂-NPs were present in both agents; their approximate sizes were 1.0 and 6.0 <i>μ</i>m in TiNpCA-1 and 1.5 <i>μ</i>m in TiNpCA-2. We considered that these agglomerates were trapped within capillaries at the beginning of perfusion. And at the end of perfusion, vessels of larger size were filled with agglomerates. These findings suggest a direct correlation between the signal intensity in m-CT imaging and the volume of contrast agent entering the vessels, indicating a quantitative aspect to the system. The low <i>K</i>-edge value of titanium (4.6 KeV) ensures that the signal intensity of the contrast agent remains unaffected at low energies (40 KeV). Lower energy levels improve the contrast-to-noise ratio. Consequently, using titanium dioxide as a contrast agent allows us to achieve a higher contrast-to-noise ratio while maintaining a favorable signal-to-noise ratio. Our results strongly support the notion that TiO₂-NPs as a contrast agents hold promise not only for investigating circulatory disorders in experimental pathology but also for uncovering new insights in anatomical physiology.</p>","PeriodicalId":47063,"journal":{"name":"International Journal of Biomedical Imaging","volume":"2025 ","pages":"6688558"},"PeriodicalIF":3.3,"publicationDate":"2025-01-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11824794/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143415826","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Qualitative and Quantitative Evaluation of the Image Quality of MDCT Multiphasic Liver Scans in HCC Patients.","authors":"Mohamed Zakaria El-Sayed, Mohammad Rawashdeh, Hend Galal Eldeen Mohamed Ali Hassan, Mohamed M El Safwany, Islam I E, Yasser I Khedr, Moustafa A Soula, Magdi A Ali","doi":"10.1155/ijbi/4163865","DOIUrl":"10.1155/ijbi/4163865","url":null,"abstract":"<p><p><b>Background:</b> The quality of CT images obtained from hepatocellular carcinoma (HCC) patients is complex, affecting diagnostic accuracy, precision, and radiation dose assessment due to increased exposure risks. <b>Objectives:</b> The study evaluated image quality qualitatively and quantitatively by comparing quality levels with an effective radiation dose to ensure acceptable quality accuracy. <b>Materials and Methods:</b> This study retrospectively reviewed 100 known HCC patients (Li-RADS-5) who underwent multidetector computed tomography (MDCT) multiphasic scans for follow-up of their health condition between January and October 2023. The evaluation involved quantitative and qualitative analyses of parameters such as SD, SNR, and CNR, as well as a qualitative assessment by two radiology consultants. The outcomes were compared, and the effective dose was calculated and compared with both quantitative and qualitative assessments of image quality. <b>Results:</b> ROC curve analysis revealed significant differences in CT image quality, with high to moderate specificity and sensitivity across all the quantitative parameters. However, multivariate examination revealed decreasing importance levels, except for CNR (<i>B</i>, 0.203; <i>p</i> = 0.001) and SD BG (<i>B</i>, 0.330; <i>p</i> = 0.002), which increased in <i>B</i>. The CNR and SD BG remained independent variables for CT image quality prediction, but no statistically significant relationship was found between the effective dose and image quality, either quantitatively or qualitatively. <b>Conclusion:</b> This study underscores the vital role of both quantitative and qualitative assessments of CT images in evaluating their quality for patients with HCC and highlights the predictive importance of CNR, SNR, and SD. These findings emphasize the value of these devices in assessing and predicting outcomes to minimize the effective dose.</p>","PeriodicalId":47063,"journal":{"name":"International Journal of Biomedical Imaging","volume":"2025 ","pages":"4163865"},"PeriodicalIF":3.3,"publicationDate":"2025-01-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11756936/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143048259","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}