{"title":"Isolated Solitary Asymptomatic Skeletal Muscle Relapse of High-Grade Lymphoma Detected on Surveillance <sup>18</sup>F- Fluorodeoxyglucose Positron Emission Tomography-Computed Tomography.","authors":"Punit Sharma","doi":"10.4103/ijnm.ijnm_49_23","DOIUrl":"10.4103/ijnm.ijnm_49_23","url":null,"abstract":"<p><p>While extranodal involvement of diffuse large B-cell lymphoma (DLBCL) is common, skeletal muscle involvement is extremely rare. Isolated skeletal muscle involvement in lymphoma is even rarer. We present here the case of a 26-year-old woman, who was diagnosed to have a solitary isolated skeletal muscle relapse of DLBCL on surveillance <sup>18</sup>F-fluorodeoxyglucose positron emission tomography-computed tomography, after completing first-line treatment, that was subsequently confirmed with biopsy.</p>","PeriodicalId":45830,"journal":{"name":"Indian Journal of Nuclear Medicine","volume":"38 4","pages":"396-397"},"PeriodicalIF":0.5,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10880861/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139933471","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Agreement between Thai Cardiovascular Risk Scores and Myocardial Perfusion Imaging: Exploring Associations and Clinical Implications.","authors":"Kitwiwat Phuangmali, Chanan Sukprakun","doi":"10.4103/ijnm.ijnm_61_23","DOIUrl":"10.4103/ijnm.ijnm_61_23","url":null,"abstract":"<p><strong>Purpose: </strong>This study aimed to assess the agreement between the Thai cardiovascular (CV) risk score or pretest probability (PTP), and myocardial perfusion imaging (MPI), and to explore the association between abnormal MPI results and higher Thai CV risk scores or PTP risk.</p><p><strong>Materials and methods: </strong>The study was conducted between March 2017 and December 2021, and included 128 patients. Myocardial perfusion gated single photon emission computed tomography imaging was performed on all patients, and agreement between the Thai CV risk score, PTP, and MPI was measured using weighted Cohen's kappa statistic. Logistic regression was used to calculate odds ratios (OR) and explore the association.</p><p><strong>Results: </strong>Fair agreement was observed between MPI and the Thai CV risk score (<i>κ</i> =0.269, <i>P</i> = 0.010), including patients with clinical chest pain (<i>κ</i> =0.367, <i>P</i> < 0.001). Subgroup analysis of patients with intermediate PTP revealed moderate agreement between MPI and the Thai CV risk score (<i>κ</i> =0.428, <i>P</i> = 0.002). Patients with intermediate (OR = 3.25, <i>P</i> = 0.010) or high (OR = 4.78, <i>P</i> = 0.001) Thai CV risk scores had significantly higher odds of having intermediate or high MPI results compared to those with low Thai CV risk scores.</p><p><strong>Conclusion: </strong>This study highlights the agreement between MPI and the Thai CV risk score and PTP. Higher Thai CV risk scores are associated with increased odds of abnormal MPI results. These findings provide valuable insights for clinical decision-making and patient management.</p>","PeriodicalId":45830,"journal":{"name":"Indian Journal of Nuclear Medicine","volume":"38 4","pages":"350-353"},"PeriodicalIF":0.5,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10880838/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139933437","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Prajwal Chauhan, Vijay Singh, Sumeet Kumar De, Mansi Gupta, Alok Nath, Manish Ora
{"title":"Extensive Pulmonary Cryptococcosis as a Presentation in an Immunocompetent Young Male: A Fluorodeoxyglucose Positron Emission Tomography/Computed Tomography Finding.","authors":"Prajwal Chauhan, Vijay Singh, Sumeet Kumar De, Mansi Gupta, Alok Nath, Manish Ora","doi":"10.4103/ijnm.ijnm_47_23","DOIUrl":"10.4103/ijnm.ijnm_47_23","url":null,"abstract":"<p><p>A 42-year-old male presented with a dry cough, breathlessness, and fever. He underwent a computed tomography that revealed large consolidation in the right lung. Biopsy revealed <i>Cryptococcus neoformans</i>. He was on antifungal for 4 months with no clinicoradiological improvement. <sup>18</sup>F- fluorodeoxyglucose positron emission tomography/computed tomography (<sup>18</sup>F-FDG PET/CT) showed consolidations in the right lung with multiple lung nodules. <sup>18</sup>F-FDG PET/CT ascertains the diagnosis of residual fungal infection and rules out extrapulmonary involvement.</p>","PeriodicalId":45830,"journal":{"name":"Indian Journal of Nuclear Medicine","volume":"38 4","pages":"394-395"},"PeriodicalIF":0.5,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10880851/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139935149","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Tejasvini Singhal, Parneet Singh, Girish Kumar Parida, Pramit Kumar, Sai Sradha P Patro, Kanhaiyalal Agrawal
{"title":"Aberrant Radioactive Iodine Uptake in Simple Ovarian Cyst: A Rare Finding.","authors":"Tejasvini Singhal, Parneet Singh, Girish Kumar Parida, Pramit Kumar, Sai Sradha P Patro, Kanhaiyalal Agrawal","doi":"10.4103/ijnm.ijnm_115_23","DOIUrl":"10.4103/ijnm.ijnm_115_23","url":null,"abstract":"<p><p>I-131 whole body scan and therapy play an important role in the follow-up of differentiated thyroid carcinoma patients for the detection of residual thyroid tissue and metastatic disease. However, various false-positive findings have been reported in the literature which can appear as metastases. Here, we present one such case, in which an I-131 posttherapy scan revealed false-positive radioactive iodine uptake which localized to a simple ovarian cyst.</p>","PeriodicalId":45830,"journal":{"name":"Indian Journal of Nuclear Medicine","volume":"38 4","pages":"387-389"},"PeriodicalIF":0.5,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10880847/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139933436","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Beware of the Coated Aorta in Fluorodeoxyglucose Positron Emission Tomography-Computed Tomography: A Specific Clue to the Diagnosis of Erdheim-Chester Disease in a Case of Brain and Orbital Lesions with Unknown Primary.","authors":"Koramadai Karuppusamy Kamaleshwaran, Elumalai Ramkumar","doi":"10.4103/ijnm.ijnm_63_23","DOIUrl":"10.4103/ijnm.ijnm_63_23","url":null,"abstract":"<p><p>Erdheim-Chester disease (ECD) is a systemic histiocytosis that can involve several organs, with severity ranging from occult to life-threatening. The disease was first described by William Chester in 1930 after working with the Austrian pathologist Jakob Erdheim. Even today, a correct diagnosis of ECD often takes years, given the rarity and variable manifestations of ECD. We present a case of a 63-year-old female presenting with multiple brain lesions, sent for fluorine-18 fluorodeoxyglucose positron emission tomography/computed tomography to find primary, and it showed hypermetabolic right occipital brain lesion, right orbital lesion, and soft tissue around the arch of the aorta (coated aorta), and final histopathology of the brain lesion confirmed histiocytosis ECD.</p>","PeriodicalId":45830,"journal":{"name":"Indian Journal of Nuclear Medicine","volume":"38 4","pages":"381-383"},"PeriodicalIF":0.5,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10880849/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139933440","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Predictive Value of Camera-based Donor Glomerular Filtration Rate Estimation on the Immediate Renal Allograft Outcome Following Live-related Renal Transplant: A Single-center Retrospective Study.","authors":"Sumeet Suresh Malapure, Sibi Oommen, Shivanand Bhushan, Mohan Varadanayakanahalli Bhojaraja, Shankar Prasad Nagaraju, Ravindra Prabhu Attur, Sucharitha Suresh, Dharshan Rangaswamy","doi":"10.4103/ijnm.ijnm_33_23","DOIUrl":"10.4103/ijnm.ijnm_33_23","url":null,"abstract":"<p><strong>Purpose of the study: </strong>The purpose of this study was to assess the association of measured glomerular filtration rate (mGFR) using camera-based method with early transplant outcomes.</p><p><strong>Methodology: </strong>Diethylenetriamine pentaacetate renograms of all voluntary kidney donors between January 2016 and December 2022 at Kasturba Hospital, Manipal, India, were retrieved for the study. Recipients' posttransplant biochemical parameters were collected and compared against donors with scaled mGFR >80 ml/min/1.73 m<sup>2</sup> (Group 1) and with mGFR between 60 and 80 ml/min/1.73 m<sup>2</sup> (Group 2). Donor-recipient pair age, anthropometric parameters, and their differences were also assessed against the immediate transplant outcome. Posttransplant immediate graft function was assessed by posttransplant nadir serum creatinine, day to achieve nadir serum creatinine, the incidence of slow graft or delayed graft function, and serum creatinine at 1-month posttransplantation. Recipients with serum creatinine of >2.5 mg/dl on posttransplant day 7 were taken as slow graft function.</p><p><strong>Results: </strong>A total of 161 donor-recipient pairs were analyzed in the study. In recipients who showed persistently high serum creatinine posttransplant, older donor age(p < 0.001), higher difference in body mass index among the donor-recipient pair (p= 0.03), and mGFR <80ml/min (p < 0.001) were significantly associated. Slow graft function was significantly more in Group II recipients, with donors having mGFR <80ml/min as compared to Group I with mGFR >80 ml/min (37.3% vs. 10.6%) (<i>P</i> < 0.001).</p><p><strong>Conclusions: </strong>Camera-based mGFR using Gates' formula is a reliable tool to predict inferior graft outcomes in the immediate posttransplant period. Kidneys from donors with mGFR of 60-80 mL/min/1.73 m<sup>2</sup> are likely to experience slow graft function in the immediate posttransplant period.</p>","PeriodicalId":45830,"journal":{"name":"Indian Journal of Nuclear Medicine","volume":"38 4","pages":"320-327"},"PeriodicalIF":0.5,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10880840/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139933474","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Serendipitous Diagnosis of Tertiary Hyperparathyroidism in a Case Purportedly thought to have Skeletal Metastases.","authors":"Rashi Goel, Jasim Jaleel, Nishikant Damle, Prateek Kaushik, Rahul Gupta, Seenu Vuthaluru, Lakshmi Radhakrishnan, Venkatesan Sampath Kumar, Madhavi Tripathi, Chandrasekhar S Bal","doi":"10.4103/ijnm.ijnm_12_23","DOIUrl":"10.4103/ijnm.ijnm_12_23","url":null,"abstract":"<p><p>Tertiary hyperparathyroidism (THPT) is characterized by over secretion of parathyroid hormone caused by long-standing secondary hyperparathyroidism. THPT can affect the bones as well as cause extraskeletal calcifications. The bony lesions often mimic multiple skeletal metastases or multiple myeloma. We report a case of a 48-year-old man with chronic kidney disease on dialysis, who presented with chief complaints of low back ache and swelling over the left clavicle. In view of clinical suspicion of malignancy with bony metastases, he underwent <sup>18</sup>F-fluorodeoxyglucose positron emission tomography/computed tomography and was subsequently found to have parathyroid adenomas, which were confirmed on <sup>99m</sup>Tc-methoxy-isobutyl-isonitrile scintigraphy.</p>","PeriodicalId":45830,"journal":{"name":"Indian Journal of Nuclear Medicine","volume":"38 4","pages":"392-393"},"PeriodicalIF":0.5,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10880846/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139933478","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Chronic Inflammatory Demyelinating Polyradiculoneuropathy as a Presentation of Plasmacytoma.","authors":"Hemant Rathore, Nirav Thaker","doi":"10.4103/ijnm.ijnm_44_23","DOIUrl":"10.4103/ijnm.ijnm_44_23","url":null,"abstract":"<p><p>Polyneuropathy, organomegaly, endocrinopathy, M protein elevation, and skin changes (POEMS) syndrome is one of the rare paraneoplastic disorders of the multiorgan association whose initialism describes the principal clinical features as polyneuropathy, organomegaly, endocrinopathy, M-protein elevation, and skin changes caused by an underlying plasma cell disorder, one of the major diagnostic criteria for which is the presence of an osseous lesion. We present a case of POEMS syndrome with nearly all signs and symptoms on clinical and hematological examinations, which was further investigated with MRI of the whole spine and 18F-fluorodeoxyglucose positron emission tomography/computed tomography scan, as the latter is a very useful imaging modality for evaluation of any paraneoplastic syndromes, including myeloproliferative disorders such as plasmacytoma or multiple myeloma, and lymphoproliferative or other malignancies.</p>","PeriodicalId":45830,"journal":{"name":"Indian Journal of Nuclear Medicine","volume":"38 4","pages":"379-380"},"PeriodicalIF":0.5,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10880843/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139935148","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}