A Perspective on Production and Quality Control of Iodine-123 Radiopharmaceutical for Applications in Nuclear Medicine.

The present work aims to provide a comprehensive analysis of the production methods for Iodine-123 (¹²³I), with a particular focus on recent advances in nuclear medicine in India and relevant future perspectives. ¹²³I, a radioisotope widely used in nuclear medicine for diagnostic imaging, plays a crucial role in the diagnosis and management of various medical conditions. It examines the historical background of ¹²³I production and their importance in the medical field, emphasizing the recent breakthroughs in the field of nuclear chemistry and radiopharmaceuticals. This work also explores the challenges associated with the production of these isotopes, including their short half-lives and complex production routes. In addition, the report highlights emerging technologies and methodologies that have shown promise for more efficient and cost-effective production of ¹²³I. Finally, the report provides an outlook on the future of radiopharmaceuticals (¹²³I and beyond) production, including the potential impact of new advancements on clinical applications and research endeavors.