Anushna S Babu, Dikhra Khan, Madhavi Tripathi, Rakesh Kumar
{"title":"A Rare Case of Early Visualization of Foregut Duplication Cyst in Meckel Scan.","authors":"Anushna S Babu, Dikhra Khan, Madhavi Tripathi, Rakesh Kumar","doi":"10.4103/ijnm.ijnm_153_23","DOIUrl":"https://doi.org/10.4103/ijnm.ijnm_153_23","url":null,"abstract":"<p><p>Enteric duplications are rare congenital anomalies, which can have varying presentations depending on the size, location, and type of mucosa present. Meckel scan, using technetium-<sup>99m</sup> pertechnetate (Tc-<sup>99m</sup> pertechnetate), is a useful modality for the detection of ectopic functioning gastric mucosa. Thoracic duplication cysts present as the initial photopenic area which is getting filled by Tc-<sup>99m</sup> pertechnetate in the delayed static images of Meckel scan. We report a rare case of foregut duplication cyst, where foregut duplication cyst is visualized earlier in Meckel scan.</p>","PeriodicalId":45830,"journal":{"name":"Indian Journal of Nuclear Medicine","volume":"39 6","pages":"445-448"},"PeriodicalIF":0.4,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12020966/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144045376","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Heterotopic Pancreas Masquerading as Omental Nodule on FAPI PET/CT.","authors":"Shrikant Vasantrao Solav, Shailendra Vasant Savale, Hemant Bhagwan Raundale, Vijaykumar Revansidha Keskar","doi":"10.4103/ijnm.ijnm_140_23","DOIUrl":"https://doi.org/10.4103/ijnm.ijnm_140_23","url":null,"abstract":"<p><p>Chylous ascites, attributed to various etiologies including malignancy, tuberculosis, ruptured lymphatics, and congenital lymphatic disorders, manifests as abdominal distension. Our patient presented with this condition, and an elevated CA 125 prompted further investigation. Flourine-18 fluorodeoxyglucose positron emission tomography/computed tomography (PET-CT) revealed a metabolically inactive omental nodule, while gallium 68 fibroblast activation protein inhibitor (Ga-68-FAPI) PET-CT demonstrated uptake in the same nodule and low-grade uptake in bilateral adnexae. Colloid liver scan ruled out chronic liver disease. Surprisingly, lymphoscintigraphy showed no lymphatic leak. Histological examination of the omental nodule confirmed heterotopic pancreas (HP) in the small bowel mesentery, with normal adnexae. This case report illuminates the diagnostic challenges entailed in HP and signifies a pioneering instance in the literature where evidence of HP was identified for the first time on Ga-68-FAPI PET-CT during the investigative process.</p>","PeriodicalId":45830,"journal":{"name":"Indian Journal of Nuclear Medicine","volume":"39 6","pages":"441-444"},"PeriodicalIF":0.4,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12020968/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144039810","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Sharjeel Usmani, Anjali Jain, Khulood Al Riyami, Hajar Almarzouqi, Vipin Velangadi Jayakrishan, Subash Kheruka, Rashid Al Sukati
{"title":"Inflammatory Mimicry: Epididymo-orchitis Masquerading as Malignancy on [18F]-FDG PET/CT Imaging.","authors":"Sharjeel Usmani, Anjali Jain, Khulood Al Riyami, Hajar Almarzouqi, Vipin Velangadi Jayakrishan, Subash Kheruka, Rashid Al Sukati","doi":"10.4103/ijnm.ijnm_92_24","DOIUrl":"https://doi.org/10.4103/ijnm.ijnm_92_24","url":null,"abstract":"<p><p>False positive findings in <sup>18</sup>F-fluorodeoxyglucose positron emission tomography-computed tomography (<sup>18</sup>F-FDG PET/CT) scans can present challenges in the accurate diagnosis and staging of various conditions. We report a case of a 52-year-old male with known adenocarcinoma of the stomach who underwent total gastrectomy and chemotherapy and was referred for <sup>18</sup>F-FDG PET/CT to rule out recurrence. <sup>18</sup>F-FDG PET/CT showed a large FDG-avid lesion involving the entire right testicle mimicking testicular cancer or lymphoma. Further evaluation with ultrasonography revealed epididymo-orchitis, possibly of granulomatous etiology. Orchitis, an inflammatory condition of the testicles, can cause misleading results in <sup>18</sup>F-FDG PET/CT imaging for cancer surveillance. Imagers should cautiously interpret PET/CT findings, considering clinical context, patient history, and additional imaging modalities to distinguish true malignancies from false positives.</p>","PeriodicalId":45830,"journal":{"name":"Indian Journal of Nuclear Medicine","volume":"39 6","pages":"466-468"},"PeriodicalIF":0.4,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12020974/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144001153","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"An Uncommon Breast Odyssey: A Rare Case of Carcinoma Breast with Mesenteric Metastasis.","authors":"Prakash Singh, Yogita Khandelwal, Kanishka Bharti, Shivam Singh","doi":"10.4103/ijnm.ijnm_5_24","DOIUrl":"https://doi.org/10.4103/ijnm.ijnm_5_24","url":null,"abstract":"<p><p>We present an unusual case of invasive ductal breast carcinoma in a postmenopausal female with a clinically node-negative disease that was incidentally found to have mesenteric metastatic deposits on <sup>18</sup>F-fluorodeoxyglucose positron emission tomography/computed tomography scan. Mesenteric metastasis from invasive breast carcinoma is rare, with <1% cases reported worldwide and limited availability of diagnostic and therapeutic protocols for carcinoma breast with mesenteric metastasis, this proved to be a challenging and intriguing case. To further accentuate the complexity, the primary tumor of this mesenteric metastasis was found to be invasive ductal carcinoma, which is even more infrequent, and <0.5% of cases have been reported till date.</p>","PeriodicalId":45830,"journal":{"name":"Indian Journal of Nuclear Medicine","volume":"39 6","pages":"463-465"},"PeriodicalIF":0.4,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12020967/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144050678","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Testicular Tuberculosis after Intravesical BCG for Urinary Bladder Cancer: A Role of FDG PET-CT.","authors":"R Arun Visakh, Senthil Raja, Thara Pratap, Renu Mariam Thomas, Vadavattathu Padmanabhan Gangadharan","doi":"10.4103/ijnm.ijnm_115_24","DOIUrl":"https://doi.org/10.4103/ijnm.ijnm_115_24","url":null,"abstract":"<p><p>Bacillus Calmette-Guërin (BCG) has been traditionally used as a vaccine against tuberculosis (TB), which contains live, attenuated strain of <i>Mycobacterium bovis</i>. However, intravesical BCG administration has been used as an immunological treatment of superficial bladder cancer. Complications after bladder instillation of BCG are rare. We report a case of carcinoma urinary bladder with histopathologically proven granulomatous epididymo-orchitis (TB) after treatment with intravesical BCG.</p>","PeriodicalId":45830,"journal":{"name":"Indian Journal of Nuclear Medicine","volume":"39 6","pages":"460-462"},"PeriodicalIF":0.4,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12020973/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144032304","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Prakash Singh, Yogita Khandelwal, Vineet Mishra, Bela Jain
{"title":"Intriguing Encounter: Unveiling Squamous Cell Carcinoma Lung with Rare Bilateral Renal and Pituitary Metastasis on [18F]-FDG PET/CT.","authors":"Prakash Singh, Yogita Khandelwal, Vineet Mishra, Bela Jain","doi":"10.4103/ijnm.ijnm_57_24","DOIUrl":"https://doi.org/10.4103/ijnm.ijnm_57_24","url":null,"abstract":"<p><p>Metastases from squamous cell carcinoma of the lung typically occur in the brain, liver, adrenal glands, bone, and regional lymph nodes. It is exceedingly uncommon to encounter multiple rare sites of metastasis from a single primary neoplasm. Herein, we describe a case of a 44-year-old male diagnosed with squamous cell carcinoma lung with pituitary and renal metastasis detected on <sup>18</sup>F-FDG (Fluorodeoxyglucose) PET/CT. <sup>18</sup>F-FDG PET/CT is the standard of care and is an integral part of the clinical staging of patients with lung cancer. According to published literature, the incidence of symptomatic pituitary and renal metastasis from squamous cell carcinoma lung is rare to find with incidences <1% and 5%, respectively. The revelation of rare sites of metastasis originating from primary squamous cell carcinoma lung, as reported in this case on FDG PET/CT, illuminates the exceptional rarity and intricacies in oncology. The exquisite sensitivity of FDG PET/CT enables the identification of occult metastasis in atypical anatomical locations, presenting a distinct advantage over conventional imaging modalities.</p>","PeriodicalId":45830,"journal":{"name":"Indian Journal of Nuclear Medicine","volume":"39 6","pages":"454-456"},"PeriodicalIF":0.4,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12020972/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144029752","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Advancing Nuclear Medicine through Discovery, Invention, and Innovation - Contribution of a Physicist and Scientist (Vikram Sarabhai Memorial Oration-2023).","authors":"Ashish Kumar Jha","doi":"10.4103/ijnm.ijnm_118_24","DOIUrl":"https://doi.org/10.4103/ijnm.ijnm_118_24","url":null,"abstract":"<p><p>The history of radiation science began with Wilhelm Rontgen's discovery of X-rays in 1895, followed closely by Henri Becquerel's discovery of radioactivity in 1896. Subsequent research focused on developing radioisotope technology and exploring its applications in medical diagnosis and treatment. The first recorded use of radioisotopes for tumor treatment was by William Dune in Marie Curie's laboratory. George D Heawse employed radioisotopes to study plant and animal physiology. Irene and Joliot Curie pioneered the production of artificial radioisotopes using alpha particle bombardment. Ernest O. Lawrence's invention of the cyclotron furthered the development of artificial isotopes. His brother John Lawrence treated the first patient with cyclotron-produced phosphorus-32. Glenn Seaborg's discovery of Tc-99m and I-131 led to the development of radioiodine therapy by Saul Hertz and many diagnostic procedures using Tc-99m. Bendit Casin invented the rectilinear scanner, a pioneering imaging device, while Hal Anger developed the gamma camera. Over time, the contributions of researchers, scientists, engineers, and physicians have advanced the field of nuclear medicine, resulting in state-of-the-art equipment such as positron emission tomography (PET)/magnetic resonance imaging (MRI), positron emission tomography (PET)/computed tomography (CT), single-photon emission computed tomography (SPECT)/computed tomography (CT), and many other innovative technologies.</p>","PeriodicalId":45830,"journal":{"name":"Indian Journal of Nuclear Medicine","volume":"39 6","pages":"421-427"},"PeriodicalIF":0.4,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12020969/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144014931","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Impact of Teleradiology on Oncological Interpretation of PET-CT Scans.","authors":"Arjun Kalyanpur, Neetika Mathur","doi":"10.4103/ijnm.ijnm_31_24","DOIUrl":"https://doi.org/10.4103/ijnm.ijnm_31_24","url":null,"abstract":"<p><strong>Background: </strong>Cancer is a prime cause of death globally and accounted for about 10 million deaths in 2020. The accurate determination of the extent of disease is crucial for treatment conceptualization and planning. The aim of the present study was to assess the role of teleradiology in the oncological interpretation of positron emission tomography-computed tomography (PET-CT) scans.</p><p><strong>Materials and methods: </strong>In this retrospective study, a total of 1137 PET-CT scans of a cohort of 1057 patients from hospitals in India, the US and Nepal were uploaded to the teleradiology cloud server and interpreted by board certified radiologists empanelled by a teleradiology service provider.</p><p><strong>Results: </strong>The telehealth model proposed in the study was seen to provide timely and quality reporting of all PET- CT studies with a mean turnaround time of 20.06 h 95% confidence interval (19.35-20.78).</p><p><strong>Conclusion: </strong>The early-stage diagnosis of cancer before it has progressed or metastasized is crucial for the immediate treatment conceptualization and plan and improves the prognosis for long-term survival of the patient. Teleradiology is an important tool in the field of oncology, providing rapid and accurate interpretation of imaging findings, essential for appropriate treatment planning.</p>","PeriodicalId":45830,"journal":{"name":"Indian Journal of Nuclear Medicine","volume":"39 6","pages":"436-440"},"PeriodicalIF":0.4,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12020965/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144014933","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Srishti Srivastava, Parag Jilhare, Aftab Hasan Nazar, Manish Ora, Sanjay Gambhir
{"title":"Isolated Muscular NK/T Cell Lymphoma: A Rare Presentation of Post-Transplant Lymphoproliferative Disorders.","authors":"Srishti Srivastava, Parag Jilhare, Aftab Hasan Nazar, Manish Ora, Sanjay Gambhir","doi":"10.4103/ijnm.ijnm_108_24","DOIUrl":"https://doi.org/10.4103/ijnm.ijnm_108_24","url":null,"abstract":"<p><p>Posttransplant lymphoproliferative disorders (PTLDs) represent a spectrum of malignancies occurring in transplant recipients under immunosuppression, often linked with Epstein-Barr Virus infection. PTLD has a varied presentation, and isolated muscular involvement is infrequent. Here, we present the case of a 47-year-old female renal transplant recipient presenting with acute left knee joint swelling, initially suggestive of an infective or inflammatory etiology. Biopsy revealed high-grade non-Hodgkin lymphoma of natural killer/T-cell lymphoma. F-18 Fluorodeoxyglucose positron emission tomography-computed tomography scan revealed metabolically active soft tissue mass lesions isolated to thigh muscles. The patient was on a modified chemotherapy regimen tailored to accommodate renal function. This case underscores the necessity for heightened vigilance in diagnosing PTLD, particularly considering its atypical presentations.</p>","PeriodicalId":45830,"journal":{"name":"Indian Journal of Nuclear Medicine","volume":"39 6","pages":"457-459"},"PeriodicalIF":0.4,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12020975/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144033946","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Differential Pattern of Brain Metabolism in Drug-naive versus Refractory OCD using [18F]-FDG PET/MRI Brain.","authors":"Shailesh Jha, Amarnath Jena, Prerana Rana, Achal Bhagat","doi":"10.4103/ijnm.ijnm_112_24","DOIUrl":"https://doi.org/10.4103/ijnm.ijnm_112_24","url":null,"abstract":"<p><p>Obsessive-compulsive disorder is among the most extensively researched mental health disorder. Various metabolic neuroimaging research findings are consistent but still nonconclusive. The major limitation is a homogeneous sample. There are research findings which have established the impact of treatment in changing brain metabolism. Therefore, it is important to highlight differential metabolic changes with respect to treatment staging and its outcome. It will also help to individualized neuromodulation protocol based on differential metabolic findings. This study highlights the distinct differential fluorodeoxyglucose metabolic changes among two distinct cases: drug-naïve and treatment-refractory.</p>","PeriodicalId":45830,"journal":{"name":"Indian Journal of Nuclear Medicine","volume":"39 6","pages":"449-453"},"PeriodicalIF":0.4,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12020964/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144050679","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}